Patent Grant
11885857
The present invention pertains to a cage in a magnetic resonance device (MRD) with a fastening/attenuating system and methods thereof.
Magnetic resonance is used in a variety of applications to analyze and image matter, including nuclear magnetic resonance (NMR) spectroscopy, electron spin resonance (ESR) spectroscopy, nuclear quadrupole resonance (NQR), and magnetic resonance imaging (MRI). The principle is that when exposed to a uniform magnetic field, the subatomic particles in an atom will align with the magnetic field. A short electromagnetic burst disturbs the alignment, producing signals from the subatomic particles. The multitude of signals can tell an investigator about the composition, structure, and location of a sample. A more uniform magnetic field will produce less noise and more precise results. In order to produce a high quality image, the magnetic field used must be extremely stable and uniform.
The use of simple permanent magnet structures, such as C-magnet and H-magnet configurations, is not enough to achieve a sufficiently uniform magnetic field. In order to achieve such uniformity, elements correcting the inhomogeneity of the magnetic field are added, according to the principle of the fields' superposition. Coils, magnetic parts, or other means of enabling correction of the principal field are added in order to obtain a homogeneous field in the zone of interest. The precise location of these contributory components is crucial.
U.S. Pat. No. 5,959,454 to Westphal et. al. discloses a magnet arrangement for an NMR tomography system, in particular for skin and surface examinations, which contains a one-sided NMR system having two ring magnets and a cylindrical magnet. Their respective locations provide a certain degree of uniformity.
U.S. Pat. No. 6,191,584 presents a permanent magnet for NMR image detection which contains a magnetic structure having a yoke and magnetic poles, so shaped as to delimit or enclose a cavity.
U.S. Pat. No. 6,946,939 discloses a packaging plate for an interlocking magnetic circuit package comprised of multiple permanent magnets.
The ability to adjust the position and attenuation of contributory magnetic fields allows for a more precise calibration of the field in the area of interest. Therefore, a cage in a magnetic resonance device with a fastening and attenuating system still meets a long-felt need.
It is one object of the invention to disclose a cage with a fastening system in an MRD (magnetic resonance device), the cage with fastening system comprising a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; and, a plurality of P face walls, where P is an integer greater than or equal to 2; and a plurality of fastening rods; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces.
It is another object of the invention to disclose a cage in a magnetic resonance device; it is characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; and a plurality of fastening screws; wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls.
It is another object of the invention to disclose a cage in a magnetic resonance device; it is characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening rods; and, a plurality of fastening screws; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces, and further wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls.
It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls defined by at least one anchoring latches suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; and a plurality of fastening screws; wherein each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein the fastening belt physically interconnects at least a portion of the circumference of the cage.
It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening rods; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces; and further wherein the fastening belt physically interconnects at least a portion of the circumference of the cage
It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening screws; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls; and further wherein each of the fastening belt physically interconnects at least a portion of the circumference of the cage.
It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening rods; a plurality of fastening screws; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces; wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls; and further wherein each of the fastening belt physically interconnects at least a portion of the circumference of the cage.
It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls defined by at least one anchoring latches suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein the fastening belt physically interconnects at least a portion of the circumference of the cage; and further wherein each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
It is another object of the invention to disclose a cage in a magnetic resonance device, characterized by shaped internal and/or external cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
It is another object of the invention to disclose a cage in a magnetic resonance device, wherein the fastening means are configured in a manner it characterized by shaped cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
It is another object of the invention to disclose a cage with a fastening/attenuating system in an MRD and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; and a plurality of Q main magnets, where Q is an integer greater than or equal to 2, at least one of the main magnets is attached to at least one pole piece; the main magnet and/or the pole piece positioned, when cage is assembled, in a three-dimensional configuration ensuring application of highest homogeneous magnetic gradient by the magnets; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of R separating/adjusting rods (SAPs), where R is an integer greater than or equal to 1, each of said SAPs oriented substantially north-south relative to the poles of said main magnets and crossing the end cover, the end cup, potentially a preset gap between the end cover and the end gap, the main magnet and the pole piece, with at least one of said SAPs being fastenable, maneuverable or otherwise adjustable by means of a controlled adjusting mechanism located adjacent to at least one end of said SAP; wherein by fastening, maneuvering or otherwise adjusting said SAP by means of the controlled adjusting mechanism, the three-dimensional configuration of the either main magnet and/or pole piece is adjusted providing a homogeneous, stable and uniform magnetic field therein.
It is another object of the invention to disclose a cage with a fastening/attenuating system in an MRD as defined above, characterized by a shaped internal and/or external cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
It is another object of the invention to disclose a cage with a fastening/attenuating system in an MRD as defined above, characterized by a a shaped cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls and a plurality of fastening rods; and (b) passing a plurality of fastening rods through at least one of the side magnets and at least one of the pole pieces and fastening them in an effective measure, such that the rods physically interconnects at least one pair of side walls.
It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; and, a plurality of fastening screws; and (b) physically interconnecting one of the face walls the fastening screws with one of the side walls.
It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; and a plurality of fastening rods; and plurality of fastening screws; and (b) passing a plurality of fastening rods through at least one of the side magnets and at least one of the pole pieces and fastening them in an effective measure, such that the rods physically interconnects at least one pair of side walls; while physically interconnecting one of the face walls the fastening screws with one of the side walls.
It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls defined by at least one anchoring latches suitable to be securely accommodated within the shaped recess; and, a plurality of fastening screws; and (b) physically interconnecting one of the face walls' anchoring latches with one of the side walls.
It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; and at least one fastening belt, optionally fastened and secured by means of ratchet; and (b) physically interconnecting at least a portion of the circumference of the cage by the fastening belt.
It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; at least one fastening belt, optionally fastened and secured by means of ratchet; and a plurality of fastening rods; and (b) passing a plurality of the fastening rods through at least one of the side magnets and at least one of the pole pieces and fastening them in an effective measure, such that the rods physically interconnects at least one pair of side walls while physically interconnecting at least a portion of the circumference of the cage by the fastening belt.
It is another object of the invention to disclose a method of attenuating the magnetic field within a sample cavity in a fastened cage of an MRD, the method comprising steps of (a) assembling a plurality of pole pieces; a plurality of main magnets; at least one of the main magnets is attached to at least one pole piece, the main magnet and/or the pole piece positioned, when cage is assembled, in a three-dimensional configuration ensuring application of highest homogeneous magnetic gradient by the magnets; a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of face walls; a plurality of R separating/adjusting rods (SAPs), where R is an integer greater than or equal to 1, each of the SAPs oriented substantially north-south relative to said main magnets and crossing the end cover, the end cup, potentially a preset gap between the end cover and the end gap, the main magnet and the pole piece, and (b) fastening, maneuvering or otherwise adjusting at least one of said SAPs by means of a controlled adjusting mechanism located adjacent to at least one end of the SAP; such that the three-dimensional configuration of the either main magnet and/or pole piece is adjusted providing a homogeneous, stable and uniform magnetic field therein.
In order to understand the invention and to see how it may be implemented in practice, a plurality of embodiments is adapted to now be described, by way of non-limiting example only, with reference to the accompanying drawings, in which
The following description is provided so as to enable any person skilled in the art to make use of the invention and sets forth the best modes contemplated by the inventor of carrying out this invention. Various modifications, however, will remain apparent to those skilled in the art, since the general principles of the present invention have been defined specifically to provide a cage in an MRD with a fastening/attenuating system and methods thereof. Therefore, the invention is not limited by that which is illustrated in the figures and described in the specification, but only as indicated in the accompanying claims, with the proper scope determined only by the broadest interpretation of said claims.
The term ‘magnetic resonance device’ (MRD) applies hereinafter to any Magnetic Resonance Imaging (MRI) device, any Nuclear Magnetic Resonance (NMR) spectroscope, any Electron Spin Resonance (ESR) spectroscope, any Nuclear Quadrupole Resonance (NQR) or any combination thereof.
The term ‘tolerance’ refers hereinafter to the interval between the corner-magnets and the cage walls, enabling displacement of the walls.
The term ‘about’ refers hereinafter to ±20% of the defined measure. The term ‘plurality’ if not otherwise specified, applies hereinafter to any integer greater than or equal to one.
The term ‘adjust’ applies hereinafter to a change of the magnet's parameters before or after assembly, to optimize the magnetic field uniformity.
The term ‘pole-piece’ applies hereinafter to an element of high permeability material used to shape the uniformity of the magnetic flux from a permanent magnet. It is in the scope of the present invention wherein the pole-magnet pieces are selected from metal alloying material, and especially from steel material.
It is in the scope of the invention wherein the term pole-piece also refers to attenuable or otherwise adjustable pole pieces, adapted to ensure a homogeneous, stable and uniform magnetic field within the diagnostic zone, interchangeably descried below as a confined volume, sample cavity etc. Hence for example, toroidal and disk-shaped rings, cubes or any other constructions can be incorporated adjacent to or within pole pieces, and extruded from ferromagnetic metals, non-ferromagnetic metals, non-metallic substances or magnetic materials.
According to an embodiment of the invention which is presented in a non-limiting manner, a steel pole piece, formed as a right solid cylindrical section approximately equal in diameter to the main magnet, is positioned in face-to-face with main magnet and main magnet face. The entire assembly is positioned within a right cylindrical or polygonal steel sleeve or cage which is closed off by a cylindrical or polygonal steel end cap. A second permanent magnet assembly is placed within the sleeve or cage in face-to-face relationship with an identical, mirror image permanent magnet assembly having substantially identical components and construction and spaced apart from the second magnet assembly to form an air gap therebetween. A steel sleeve extends to enclose the magnet assemblies and the air gap. A pair of removable side walls allows access to the air gap when removed from sleeve or cage. Permanent magnet assemblies opposite in polarity create a magnetic flux field across the air gap. A centrally located segment of the air gap is identified as a diagnostic zone across which the magnetic flux is at its most powerful and uniform.
The term ‘side-magnets’ applies hereinafter to permanent magnets arranged around the sides of pole-pieces. It is in the scope of the invention wherein at least a portion of side-magnets are superconductors or ferromagnets.
It is thus one embodiment of the present invention to provide an efficient cage of an MRD for providing a homogeneous, stable and uniform magnetic field therein, characterized by an outside shell. A fastening system, integrated within the cage, is disclosed and shown in alternative configurations (1A and 1B) in
Rods (100) are at least partially made of materials selected in a non-limiting manner from a group consisting of metals, especially stainless steel, polymers, composite materials and mixtures thereof. It is in the scope of the invention wherein the rods are an elongated members characterized by a shaped cross-section, the shape is selected in a non-limiting manner form a group consisting of rectangular, polygonal, rounded, twisted round, curved, having a crescent form, recess, niche, bores or notches, screws and a combination thereof.
It is still in the scope of the present invention wherein at least one of the cage's walls is interconnected with an adjacent wall via a lip-containing connection defining a tolerance enabling the cage's wall to displace, and to prevent leakage of the cage's magnetic field.
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in
Fastening belt (400) is at least partially made of materials selected in a non-limiting manner from a group consisting of metals, especially stainless steal, polymers, composite materials and mixtures thereof. The fastening belt is constructed from flexible or non flexible materials. The belt may be narrow or wide. A net comprising a plurality of belts, e.g., some of them incorporated within others, is a useful option.
According to another embodiment of the invention, a cage in an MRD with a fastening/attenuating system (11) is disclosed and shown in
It is also in the scope of the invention wherein a set of two or more fastening abutments (300) and/or at least one fastening belt (400) physically interconnects at least a portion of the circumference of the cage. Also in the scope of the invention is a cage in an MRD with a fastening/attenuating system (11) with at least one anchoring latch suitable to be securely accommodated within a shaped recess as defined above.
Reference is now made to
According to another embodiment of the invention, a cage in an MRD with a fastening/attenuating system (12) is disclosed and shown in
Hence for example, recess 130 is a disk groove adapted to place disk 140. The disk, located in a recess positioned adjacent to the measuring volume (130), and/or in an opposite location (131), is either made of continuous and homogeneous/heterogeneous composition (see 140 for example), or otherwise provided with one or more bores (See 142) adapted to contain one or more attenuating means (143) of various shapes, sizes and compositions. Additionally or alternatively, pole piece 45 comprises one or more lateral recesses, such as a groove positioned adjacent to the measuring volume (132), and/or a groove located in the opposite direction (133). Grooves 132 and/or 133 adapted to contain rings of any size, shape and composition, such as rectangular (polygonal) cross-section (144), cylindrical or ellipsoidal cross-section (145), etc.
By fastening, maneuvering or otherwise adjusting the SAP by means of the controlled attenuating mechanism, the three-dimensional configuration of the main magnet and/or pole piece is adjusted, providing both (i) a homogeneous, stable and uniform magnetic field therein and (ii) a relatively large sample cavity confined by the cage, within which a sample is introduced.
In another embodiment of the present invention a method of obtaining an integratably fastened cage is disclosed, comprising a step of incorporating at least one internal (integrated) fastening means as defined above, e.g., fastening rods, fastening screws, anchoring latches etc.
In another embodiment of the present invention a method of obtaining a non-integrated fastened cage is disclosed, comprising a step of incorporating at least one external (non-integrated) fastening means as defined above, e.g., a fastening belt.
In another embodiment of the present invention a method of obtaining an integratably sensitively-attenuated cage of an MRD is disclosed. The method comprises steps of (a) providing an MRD as defined above; (b) incorporating a plurality of SAPs within the cage, and optionally further incorporating either or both (i) at least one internal (integrated) attenuating means as defined above, e.g., fastening rods, fastening screws, anchoring latches etc., and (ii) at least one external (non-integrated) fastening means as defined above, e.g., a fastening belt; and (c) fastening, maneuvering or otherwise adjusting the SAP or SAPs by means of a controlled-attenuating mechanism thus providing a homogeneous, stable and uniform magnetic field in sample cavity confined by the cage, within which a sample is introduced.
This application claims priority from U.S. Provisional Application No. 61/221,571, filed 30 Jun. 2009.
| Number | Name | Date | Kind |
|---|---|---|---|
| 3534251 | Edward | Oct 1970 | A |
| 4612505 | Zijlstra | Sep 1986 | A |
| 4698611 | Vermilyea | Oct 1987 | A |
| 4758813 | Holsinger | Jul 1988 | A |
| 4899109 | Tropp | Feb 1990 | A |
| 4931733 | Hanawa | Jun 1990 | A |
| 5235284 | Tahara | Aug 1993 | A |
| 5343151 | Cory | Aug 1994 | A |
| 5359310 | Pissanetzky | Oct 1994 | A |
| 5539316 | Sukumar | Jul 1996 | A |
| 5565834 | Hanley | Oct 1996 | A |
| 5635889 | Stelter | Jun 1997 | A |
| 5664569 | Damadian | Sep 1997 | A |
| 5760585 | Dorri | Jun 1998 | A |
| 5959454 | Westphal | Sep 1999 | A |
| 6081120 | Shen | Jun 2000 | A |
| 6147578 | Panfil | Nov 2000 | A |
| 6157278 | Katznelson | Dec 2000 | A |
| 6177795 | Zhu | Jan 2001 | B1 |
| 6191584 | Trequattrini | Feb 2001 | B1 |
| 6411187 | Rotem | Jun 2002 | B1 |
| 6452388 | Reiderman | Sep 2002 | B1 |
| 6535092 | Hurley | Mar 2003 | B1 |
| 6600401 | Zuk | Jul 2003 | B2 |
| 6646530 | Manfred | Nov 2003 | B2 |
| 6687526 | Martin | Feb 2004 | B2 |
| 6707363 | Abele | Mar 2004 | B1 |
| 6751496 | Su | Jun 2004 | B2 |
| 6799366 | Tsuda | Oct 2004 | B2 |
| 6838964 | Knight | Jan 2005 | B1 |
| 6897750 | Neuberth | May 2005 | B2 |
| 6946939 | Doi | Sep 2005 | B2 |
| 7034530 | Ahluwalia | Apr 2006 | B2 |
| 7116198 | Abele | Oct 2006 | B1 |
| 7148689 | Huang | Dec 2006 | B2 |
| 7205764 | Anderson | Apr 2007 | B1 |
| 7400147 | Rapoport | Jul 2008 | B2 |
| 7423431 | Amm | Sep 2008 | B2 |
| 7529575 | Rezzonico | May 2009 | B2 |
| 7551954 | Green | Jun 2009 | B2 |
| 7719279 | Rapoport | May 2010 | B2 |
| 7800368 | Vaughan | Sep 2010 | B2 |
| 7812607 | Damadian | Oct 2010 | B2 |
| 8089281 | Zhai | Jan 2012 | B2 |
| 8319496 | Eryaman | Nov 2012 | B2 |
| 8405479 | Cleveland | Mar 2013 | B1 |
| 8807084 | Rapoport | Aug 2014 | B2 |
| 8851018 | Rapoport | Oct 2014 | B2 |
| 8896310 | Rapoport | Nov 2014 | B2 |
| 8969629 | Takasuka | Mar 2015 | B2 |
| 8969829 | Wollenweber | Mar 2015 | B2 |
| 9100111 | Behrendt | Aug 2015 | B2 |
| 9157975 | Dale | Oct 2015 | B2 |
| 9159479 | Rotem | Oct 2015 | B2 |
| 9448294 | Rapoport | Sep 2016 | B2 |
| 9696269 | Fordham | Jul 2017 | B2 |
| 10094896 | Rapoport | Oct 2018 | B2 |
| 10996297 | Rapoport | May 2021 | B2 |
| 20010013779 | Marek | Aug 2001 | A1 |
| 20020050895 | Zuk | May 2002 | A1 |
| 20050030028 | Clarke | Feb 2005 | A1 |
| 20050043612 | Saint-Jalmes | Feb 2005 | A1 |
| 20050151539 | Aoki | Jul 2005 | A1 |
| 20070068862 | Sisemore | Mar 2007 | A1 |
| 20070096737 | Rapoport | May 2007 | A1 |
| 20070108850 | Chertok | May 2007 | A1 |
| 20070249928 | Blezek | Oct 2007 | A1 |
| 20070265520 | Posse | Nov 2007 | A1 |
| 20070273378 | Trequattrini | Nov 2007 | A1 |
| 20080001601 | Sellers | Jan 2008 | A1 |
| 20080246476 | Rapoport | Oct 2008 | A1 |
| 20080259560 | Lvovsky | Oct 2008 | A1 |
| 20090072939 | Shen | Mar 2009 | A1 |
| 20090085700 | Lian | Apr 2009 | A1 |
| 20090120615 | Icoz | May 2009 | A1 |
| 20090259560 | Bachenheimer | Oct 2009 | A1 |
| 20110090033 | Sankar | Apr 2011 | A1 |
| 20110162652 | Rapoport | Jul 2011 | A1 |
| 20110186049 | Rapoport | Aug 2011 | A1 |
| 20110234347 | Rapoport | Sep 2011 | A1 |
| 20110304333 | Rapoport | Dec 2011 | A1 |
| 20120071745 | Rapoport | Mar 2012 | A1 |
| 20120073511 | Rapoport | Mar 2012 | A1 |
| 20120077707 | Rapoport | Mar 2012 | A1 |
| 20120119742 | Rapoport | May 2012 | A1 |
| 20120124806 | Rapoport | May 2012 | A1 |
| 20130079624 | Rapoport | Mar 2013 | A1 |
| 20130109956 | Rapoport | May 2013 | A1 |
| 20130237803 | Rapoport | Sep 2013 | A1 |
| 20130328559 | Rapoport | Dec 2013 | A1 |
| 20130328560 | Rapoport | Dec 2013 | A1 |
| 20130328563 | Rapoport | Dec 2013 | A1 |
| 20140050827 | Rapoport | Feb 2014 | A1 |
| 20140051973 | Rapoport | Feb 2014 | A1 |
| 20140051974 | Rapoport | Feb 2014 | A1 |
| 20140051976 | Rapoport | Feb 2014 | A1 |
| 20140099010 | Rapoport | Apr 2014 | A1 |
| 20140103927 | Rapoport | Apr 2014 | A1 |
| 20140117989 | Rapoport | May 2014 | A1 |
| 20140128725 | Rapoport | May 2014 | A1 |
| 20140139216 | Rapoport | May 2014 | A1 |
| 20140142914 | Rapoport | May 2014 | A1 |
| 20140152302 | Rapoport | Jun 2014 | A1 |
| 20140152310 | Rapoport | Jun 2014 | A1 |
| 20140158062 | Rapoport | Jun 2014 | A1 |
| 20140230850 | Rapoport | Aug 2014 | A1 |
| 20140257081 | Rapoport | Sep 2014 | A1 |
| 20140266203 | Rapoport | Sep 2014 | A1 |
| 20140300358 | Rapoport | Oct 2014 | A1 |
| 20140378821 | Rapoport | Dec 2014 | A1 |
| 20140378825 | Rapoport | Dec 2014 | A1 |
| 20150059157 | Rapoport | Mar 2015 | A1 |
| 20150059655 | Rapoport | Mar 2015 | A1 |
| 20150061680 | Leskowitz | Mar 2015 | A1 |
| 20150065788 | Rapoport | Mar 2015 | A1 |
| 20150077105 | Rapoport | Mar 2015 | A1 |
| 20150137812 | Rapoport | May 2015 | A1 |
| 20150168519 | Rapoport | Jun 2015 | A1 |
| 20150253397 | Rapoport | Sep 2015 | A1 |
| 20150253400 | Rapoport | Sep 2015 | A1 |
| 20150253401 | Rapoport | Sep 2015 | A1 |
| 20160022123 | Katznelson | Jan 2016 | A1 |
| 20160032712 | Frosell | Feb 2016 | A1 |
| 20190250226 | Rapoport | Aug 2019 | A1 |
| Number | Date | Country |
|---|---|---|
| 2863080 | Aug 2013 | CA |
| 102136337 | Jul 2011 | CN |
| 0921527 | Jun 1999 | EP |
| 0921537 | Jun 1999 | EP |
| 1619667 | Jan 2006 | EP |
| 272863 | Oct 1927 | GB |
| 863272 | Mar 1961 | GB |
| 2005074608 | Aug 2005 | WO |
| 2007052275 | May 2007 | WO |
| 2011001429 | Jan 2011 | WO |
| 2014141251 | Sep 2014 | WO |
| Entry |
|---|
| European Patent Office Invitation Pursuant to Rule 137(4) EPC and Article 94(3) EPC issued in App. No. EP12151115 dated May 19, 2022, 5 pages. |
| Extended European Search Report for Application No. EP19179551.7, dated Jan. 7, 2020, 9 pages. |
| Belov, A. et al. Passive Shimming of the Superconducting Magnet for MRI, IEEE Transactions on Applied Superconductivity, Jun. 1995, vol. 5, No. 2, 679-681. |
| Liming Hong and Donglin Zu, Shimming Permanent Magnet of MRI Scanner, Piers Online, 2007, vol. 3, No. 6, 859-864. |
| McGinley et al., A permanent MRI magnet for magic angle imaging having its field parallel to the poles, Journal of Magnetic Resonance, 2016, 271; 60-67. |
| R Prost and L F Czervionke, How does an MR scanner operate? American Journal of Neuroradiology, Aug. 1994, 15 (7) 1383-1386. |
| Yingying Yao, Yong-Kwon Choi and Chang-Seop Koh, The Optimal Design of Passive Shimming Elements for High Homogenous Permanent Magnets Utilizing Sensitivity Analysis, Journal of Electrical Engineering & Technology, 2006, vol. 1, No. 4, pp. 461-465. |
| Z. Ren et al. “Study On Shimming Method for Open Permanent Magnet of MRI”, Progress in Electromagnetics Research M, vol. 6, 23-34, 2009. |
| Supplementary Partial European Search Report for Application No. EP10779325.2, dated Jul. 9, 2013. (3 pages). |
| Partial European Search Report for Application No. EP12151115.8, dated Jul. 31, 2013. (3 pages). |
| Notice of Allowance for U.S. Appl. No. 13/338,633, dated Jul. 30, 2014 (pp. 1-8). |
| Keith Wachowicz, “Evaluation of Active and Passive Shimming in Magnetic Resonance Imaging”, Research and Reports in Nuclear Medicine.1-12, 2014. |
| Office Action for U.S. Appl. No. 13/381,124 dated Aug. 3, 2015. (6 pages). |
| International Search Report and Written Opinion dated Nov. 9, 2010 in corresponding International Application No. PCT/IL2010/00519. (7 pages). |
| International Preliminary Report on Patentability dated Sep. 28, 2011 in corresponding International Application No. PCT/IL2010/000519. (7 pages). |
| Aspect Imaging Ltd., “Mechanical Clutch for MRI”, co-pending U.S. Appl. No. 14/611,379, filed Feb. 2, 2015. |
| Aspect Imaging Ltd., “Foamed Patient Transport Incubator”, co-pending U.S. Appl. No. 14/531,289, filed Nov. 3, 2014. |
| Aspect Imaging Ltd., “Incubator Deployable Multi-Functional Panel”, co-pending U.S. Appl. No. 14/619,557, filed Feb. 11, 2015. |
| Aspect Imaging Ltd., “Shutting Assembly for Closing an Entrance of an MRI Device”, co-pending U.S. Appl. No. 14/540,163, filed Nov. 13, 2014. |
| Aspect Imaging Ltd, “MRI—Incubator's Closure Assembly”, co-pending U.S. Appl. No. 14/539,442, filed Nov. 12, 2014. |
| Aspect Imaging Ltd. “MRI Thermo-Isolating Jacket”, co-pending U.S. Appl. No. 14/623,039, filed Feb. 16, 2015. |
| Aspect Imaging Ltd. “MRI RF Shielding Jacket”, co-pending U.S. Appl. No. 14/623,051, filed Feb. 16, 2015. |
| Aspect Imaging Ltd., “Incubator's Canopy with Sensor Dependent Variably Transparent Walls and Methods for Dimming Lights Thereof”, co-pending U.S. Appl. No. 14/453,909, filed Aug. 7, 2014. |
| Rapoport, Uri, “RF Shielding Conduit in an MRI Closure Assembly”, co-pending U.S. Appl. No. 14/574,785, filed Dec. 18, 2014. |
| Indian Examination Report for Application No. IN206/DELNP/2012, dated Aug. 13, 2019, 7 pages. |
| Aspect Imaging Ltd., “Means for Operating an MRI Device Within a RF-Magnetic Environment”, co-pending U.S. Appl. No. 14/596,320, filed Jan. 14, 2015. |
| Aspect Imaging Ltd., “Means and Method for Operating an MRI Device Within a RF-Magnetic Environment”, copending U.S. Appl. No. 14/596,329, filed Jan. 14, 2015. |
| Office Action dated Feb. 27, 2020 for U.S. Appl. No. 16/129,953 (pp. 1-7). |
| Office Action dated Jun. 22, 2020 for U.S. Appl. No. 16/129,953 (pp. 1-9). |
| Notice of Allowance dated Jan. 1, 2021 for U.S. Appl. No. 16/129,953 (pp. 1-5). |
| Aspect Imaging Ltd., “System and Method for Generating Invasively Hyperpolarized Images”, co-pending U.S. Appl. No. 14/556,682, filed Dec. 1, 2014. |
| Aspect Imaging Ltd., “System and Method for Generating Invasively Hyperpolarized Images”, co-pending U.S. Appl. No. 14/556,654, filed Dec. 1, 2014. |
| Aspect Imaging Ltd., “MRI With Magnet Assembly Adapted for Convenient Scanning of Laboratory Animals With Automated RF Tuning Unit”, co-pending U.S. Appl. No. 14/581,266, filed Dec. 23, 2014. |
| Aspect Imaging Ltd., “Capsule for a Pneumatic Sample Feedway”, co-pending U.S. Appl. No. 14/626,391, filed Feb. 19, 2015. |
| Aspect Imaging Ltd., Temperature-Controlled Exchangeable NMR Probe Cassette and Methods Thereof, co-pending U.S. Appl. No. 14/504,890, filed Oct. 2, 2014. |
| Aspect Imaging Ltd., “Nmr Extractable Probe Cassette Means and Methods Thereof”, co- pending U.S. Appl. No. 14/504,907, filed Oct. 2, 2014. |
| Aspect Imaging Ltd., CT/MRI Integrated System for the Diagnosis of Acute Strokes and Methods Thereof, copending U.S. Appl. No. 14/598,517, filed Jan. 16, 2015, 43 pages. |
| Aspect Imaging Ltd., RF Automated Tuning System Used in a Magnetic Resonance Device and Methods Thereof, co-pending U.S. Appl. No. 14/588,741, filed Jan. 2, 2015. |
| Aspect Imaging Ltd., “A Method for Manipulating the MRI's Protocol of Pulse-Sequences”, co-pending U.S. Appl. No. 14/070,695, filed Nov. 4, 2013. |
| Aspect Imaging Ltd., “Cage in an MRD with a Fastening/Attenuating System”, co-pending U.S. Appl. No. 14/527,950, filed Oct. 30, 2014. |
| EPO Communication pursuant to Article 94(3) issued in App. No. EP19179551.7, dated Aug. 31, 2023, 10 pages. |
| Number | Date | Country | |
|---|---|---|---|
| 20220091205 A1 | Mar 2022 | US | |
| 20230148452 A9 | May 2023 | US |
| Number | Date | Country | |
|---|---|---|---|
| 61221571 | Jun 2009 | US |
| Number | Date | Country | |
|---|---|---|---|
| Parent | 13381124 | US | |
| Child | 13338633 | US |
| Number | Date | Country | |
|---|---|---|---|
| Parent | 16129953 | Sep 2018 | US |
| Child | 17307604 | US | |
| Parent | 14527950 | Oct 2014 | US |
| Child | 16129953 | US | |
| Parent | 13338633 | Dec 2011 | US |
| Child | 14527950 | US |
