The present invention relates to the field of magnetic resonance imaging. More particularly, the present invention relates to a magnetic resonance imaging apparatus, and in particular a magnetic resonance imaging apparatus provided with a magnetic assembly capable of imposing a main magnetic field in an analysis zone.
Magnetic resonance imaging (MRI) is currently widely used to image, non-invasively, the interior of bodies and in particular human bodies. In particular, magnetic resonance imaging makes it possible to probe the hydrogen nuclei, and in particular their nuclear spin, of water molecules forming part of the body.
In this respect, an MRI apparatus is provided with a magnet intended to impose on the body a static magnetic field (called “main magnetic field”), under the effect of which the nuclear spins associated with the hydrogen nuclei contained in the water molecules forming part of this body polarize.
In particular, the magnetic moments associated with these spins are preferentially aligned along an axis called the z axis, determined by the orientation of the main magnetic field so as to create a magnetization of the body.
An MRI apparatus also comprises gradient coils configured to produce magnetic fields of small amplitude and varying in space when a current is applied thereto. More particularly, the gradient coils are designed to produce a magnetic field component that is aligned parallel to the main magnetic field, and which varies linearly in amplitude with the position along one of the axes x, y or z (with each pair of axes x, y and z being perpendicular).
Thus, the combined effects of the magnetic fields imposed by the gradient coils make it possible to spatially encode each of the positions of the body intended to be probed.
An MRI apparatus also comprises at least one radiofrequency (RF) coil intended to act as an RF receiver transmitter. In particular, the at least one radiofrequency coil is configured to emit RF energy pulses of a frequency equal to or close to the resonance frequency of the hydrogen nuclei spins and which is at least partially absorbed by these nuclei.
As soon as the RF emission is interrupted, the nuclear spins relax in order to return to their initial energy state and in turn emit a RF signal capable of being collected by at least one RF coil. This RF signal is then processed using a computer and reconstruction algorithms in order to obtain an image of the body.
The main magnetic field, generally comprised between 1.5 Tesla and 3 Tesla, makes it possible to achieve relatively reasonable signal-to-noise ratios and consequently to form images of the human body of sufficient quality and the duration of the order of one minute or more.
However, there are circumstances in which it is not possible to implement a main magnetic field of such an intensity. Portable MRI apparatuses are an example thereof. The latter generally comprise a permanent magnet or electromagnets of limited capacity, and cannot impose a main magnetic field with an intensity greater than 60 mT, or even greater than 200 mT, without adversely affecting the mass or bulk of the MRI apparatus considered.
This limitation in terms of main magnetic field intensity directly affects the performance of the MRI apparatus. The improvement in the uniformity of the main magnetic field may therefore be essential.
One aim of the present invention is to propose a magnetic resonance imaging apparatus enabling the analysis of different parts of the body regardless of their size without degrading the quality of the images that can be obtained on these various body parts.
An aim of the present invention is to propose a magnetic resonance imaging apparatus, advantageously implementing a main magnetic field of low intensity, provided with a magnetic assembly where the uniformity of the magnetic field created is improved with respect to the assemblies known from the prior art.
The aim of the invention is achieved by a magnetic resonance imaging apparatus that comprises:
According to an embodiment, the magnetic assembly comprises:
According to one embodiment, the magnetic assembly comprises a main part inserted between two secondary parts, the main part consisting of support plates, called main support plates, and both secondary parts being formed by support plates called secondary support plates, the opening of the main support plates, called first opening, has a first diameter, while the opening of the secondary support plates, called second opening, has a second diameter less than the first diameter.
According to one embodiment, the support plates comprise a non-magnetic material, advantageously, the non-magnetic material comprises aluminum, a plastic material, for example PMMA plexiglass.
According to one embodiment, the alignment means comprise threaded rods essentially parallel to the main axis and now secured to one another, the support plates.
According to one embodiment, each support plate is enclosed between two cover plates by gripping means, the two cover plates being configured to retain the magnets of the first plurality of magnets in the first cavities of the support plate under consideration, the gripping means advantageously comprising nuts cooperating with the threaded rods.
According to one embodiment, each support plate comprises an opening, called an alignment opening, so that the magnetic assembly comprises at least one alignment passage of square or rectangular cross-section formed by the alignment openings, and which extends parallel to the main axis; the magnetic assembly further comprising at least one alignment tube passing through the alignment passage, and having a shape in accordance with the cross-section of said passage, said at least one alignment tube being intended to fix the magnetic assembly to a trolley.
According to one embodiment, each support plate comprises a first plate and a second plate assembled against one another by a contact face, the first recesses each comprising two cavities formed from the contact face of one and/or the other of the first plate and the second plate.
According to one embodiment, the alignment means comprise at least one rail provided with alignment notches, each alignment notch holding a support plate, the notches being configured to maintain a predetermined spacing into two adjacent support plates.
According to one embodiment, the alignment means comprise an alignment element provided with a base topped by a cradle hole on a cylinder portion on an inner surface of which grooves are formed, each of the support plates being held in a groove specific to it.
According to one embodiment, each support plate comprises an outer tongue that extends radially to the annular section and which is inserted into a cavity formed at the bottom of the groove holding said support plate.
According to one embodiment, the annular parts are held together with the plurality of support plates by threaded rods, called auxiliary threaded rods.
According to one embodiment, the support plates comprise internal or external tabs wherein housings are formed that are able to house one or several permanent magnets.
According to one embodiment, the annular parts are arranged in the main housing.
According to one embodiment, the annular parts are arranged externally to the main housing, each annular part is inserted between two support plates.
According to one embodiment, said magnetic assembly further comprising a radiofrequency coil and gradient coils arranged in the main housing and mechanically integral with the magnetic assembly.
According to one embodiment, the radiofrequency coil and the gradient coils are removable.
Other characteristics and advantages of the invention will emerge from the following detailed description of the invention with reference to the appended figures, in which:
The invention relates to a magnetic resonance imaging apparatus that comprises:
The magnetic assembly is in particular intended to impose, on a body, a static magnetic field, under the effect of which the nuclear spins associated with the hydrogen nuclei contained in the water molecules partly forming this body polarize.
In particular, the magnetic assembly comprises a plurality of support plates, each having an annular section delimiting an opening, called support opening. More particularly, the support plates are assembled integrally with each other by alignment means, along a main axis, so that the support openings, aligned along the main axis, delimit a main housing of generally cylindrical shape. Each support plate further comprising a first plurality of permanent magnets, housed in first housings provided in the annular section, according to at least one annular Halbach array around the main axis. The assembly of support plates is in particular arranged to create a primary magnetic field in a zone, called analysis zone, of the main housing that presents a first uniformity.
The magnetic assembly also comprises annular parts arranged coaxially to the annular sections and secured to the support plates. Each annular part comprises a second plurality of magnets housed in second housings provided in said annular part. The annular parts are, in this respect, arranged so as to create a secondary magnetic field in the analysis zone so that the resultant of the primary magnetic field and of the secondary magnetic field, called the main field, in the analysis zone, has a second uniformity improved with regard to the first uniformity.
According to the terms of the present invention, it is understood that the analysis zone comprises a central section of the main housing. It is also understood that the analysis zone is at least delimited by the annular parts positioned at both ends, along the main axis, of the assembly formed by the annular parts.
“Uniformity of a magnetic field” is understood to mean a spatial variation of the magnetic field in the analysis zone. According to the present invention, the spatial variation of the magnetic field can in particular be characterized by the difference between the maximum magnetic field and the minimum magnetic field observed in the analysis zone. Thus, according to the principles of the present invention, the lower this difference, the better the uniformity.
The modular character of the imaging apparatus according to the present invention makes it possible to consider different first modules, each first module being adapted for the analysis of a particular section of a body. In particular, a first module can be considered for the analysis of the cranium and another first module suitable for analyzing a limb, in particular a leg.
In [
The magnetic assembly 1A in particular comprises a plurality of support plates 10. Each support plate 10 is generally planar in shape and comprises two main faces essentially parallel to one another. A support plate 10 may comprise a non-magnetic material, and in particular aluminum, or a plastic material, for example PMMA plexiglass.
As shown in [
The support plate 12 also comprises a plurality of through openings, also opening onto each of the two main faces, and forming housings, called first recesses 14. More particularly, the first recesses 14 are formed on the annular section 11 of the support plate 10 in question. In particular, and as shown in [
The magnetic assembly 1A also comprises a first plurality of permanent magnets 13. The choice of these magnets is left to the assessment of a person skilled in the art.
The magnets 13 are in particular housed individually in the first recesses in order to form an annular Halbach array. More particularly, still with reference to [
According to the present invention, the support plates 10 are assembled integrally with each other by alignment means. More particularly, the support plates 10 are assembled so that each support plate 10 has one of its main faces opposite a main face of a support plate 10 that is directly adjacent to it. Furthermore, a spacing E may be imposed between two adjacent support plates.
According to this configuration, the annular sections 11 delimit a housing, called main recess 16, of generally cylindrical shape around a main axis AA′ ([
All of the magnets of the first plurality of magnets 13, according to annular Halbach arrays, create a primary magnetic field in a zone, called analysis zone, of the main housing that presents a first uniformity.
Still according to this first embodiment, the magnetic assembly 1A also comprises cover plates 17 of generally planar shape and which also comprise an opening, called the covering opening, which can be circular.
In particular, each support plate 10 is associated with two cover plates 17 specific to it. In particular, each support plate 10 is clamped between two cover plates 17. More particularly, when the cover plates 17 enclose a given support plate 10, they are configured to retain the magnets 13 in the first recesses 14 of the support plate 10 under consideration.
The cover plates 17 may comprise a non-magnetic material, and in particular aluminum, or a plastic material, for example PMMA plexiglass.
It is understood, without it being necessary to specify it, that the covering opening has a shape and dimensions that are similar to those of the main opening. In other terms, the shape and dimensions of the covering opening do not cause the definition of the main housing as considered in the present invention.
The magnetic assembly 1A may comprise a main part 2 inserted between two secondary parts 3 and 4 ([
Still according to this first embodiment, the alignment means comprise threaded rods 15 essentially parallel to the main axis AA′ and holding the support plates 10 ([
The magnetic assembly 1A may also comprise at least one alignment passage, for example two alignment passages, which extends parallel to the main axis AA′, and of section (in a plane parallel to the main axis AA′) or rectangular. The alignment passage can in particular be formed by a succession of openings, called alignment openings, passing through the support plates 10 on the side. It is understood that the cover plates 17 also comprise alignment openings.
The magnetic assembly 1A can also comprise at least one alignment tube 50 passing through the alignment passage, and having a shape in accordance with the cross-section of said passage ([
The magnetic assembly 1A also comprises a plurality of annular parts 19 arranged coaxially to the annular sections 11, and secured to the support plates 10. For example, the annular parts 19 are held together and the plurality of support plates by threaded rods, called auxiliary threaded rods 21 ([
Saw a first variant of the first embodiment, the annular parts 19 are arranged in the main housing 16 ([
According to a second variant of the first embodiment shown in [
Each annular part 19 comprises two faces, called auxiliary faces, and parallel to the main faces of the support plates 10. Second recesses 20 are formed in each of the annular parts 19. More particularly, the second recesses of an annular part 19 open by one and the other of the auxiliary faces of the annular part under consideration.
The magnetic assembly 1A also comprises a second plurality of permanent magnets. The choice of these magnets is left to the assessment of a person skilled in the art.
Each permanent magnet of the second plurality of permanent magnets is individually housed in the second housing.
Furthermore, and according to the present invention, the annular parts 19 are arranged so as to create a secondary magnetic field in the analysis zone 22 so that the resultant of the primary magnetic field and of the secondary magnetic field, called main field, in the analysis zone, has a second improved uniformity with regard to the first uniformity.
The analysis zone 22 corresponds to an internal volume defined by the annular parts 19.
The arrangement of the magnets of the second plurality of permanent magnets can be determined by implementing a digital simulation method, and more particularly implementing a genetic algorithm. The person skilled in the art wishing to implement a genetic algorithm may in particular take up the principles described in the following article: S. Binia and S. S. Sathya, “SurveyBio inspired Optimization Algorithms”, International Journal of Soft Computing and Engineering, vol. 2, issue 2, pp. 137-151, May 2012.
According to an advantageous variant, the support plates 10 comprise internal 23 or external (not shown) tabs wherein housings capable of accommodating one or several permanent magnets are formed ([
The latter aspect also makes it possible to reduce the non-uniformity of the main magnetic field in the analysis zone.
More particularly, this second embodiment differs from the first embodiment in that the implementation of the cover plates is not considered. The spacing E between two adjacent support plates 10 is always considered in this second embodiment.
Thus, and according to this second embodiment, a support plate 10, as shown in [
In particular, the first plate 25 and the second plate 26 are assembled together by a contact face. In particular, the first plate 25 comprises a first contact face 25 A while the second plate 26 comprises a second contact face 26 A in contact with the first contact face 25 A.
The assembly of the first plate 25 with the second plate 26 may in particular implement a set of screws.
According to this second embodiment, each first recess 14 is formed by a first cavity 14A and a second cavity 14B formed respectively in the first plate and the second plate 26 ([
More particularly, the first cavity 14 A emerges by the first contact face A, while the second cavity 14B emerges by the second contact face 26 A.
It is understood that the face opposite the first contact face 25 A of the first plate 25 forms one of the main faces of the support plate, while the face opposite the second contact face 26 A of the second plate 26 forms the other of the main faces of said support plate.
According to a variant of the embodiments presented above, the alignment means comprise at least one rail 27 provided with alignment notches 28 ([
Advantageously, the alignment notches 28 are configured to maintain a predetermined spacing into two adjacent support plates 10. Furthermore, the rail 27 can be fixed to the support plates 10 with screws.
As shown in [
Advantageously, each support plate 10 comprises an external tongue 33 which extends radially to the annular section is inserted into a cavity 34 formed at the bottom of the groove holding said support plate.
The arrangements proposed in the present invention make it possible to ensure the overall cohesion of the magnetic assembly 1A. Indeed, the first plurality of magnets, as well as the second plurality of magnets, generates magnetic forces likely to lead to mechanical instability of said magnetic assembly. The implementation of the holding means as described in the present invention makes it possible to compensate for these effects.
Moreover, the consideration of the annular parts 19 makes it possible to compensate, at least in part, the inhomogeneities of the main magnetic field imposed in the analysis zone.
Regardless of the embodiment considered, and as shown by way of example in [
The gradient coils are configured to produce small-amplitude magnetic fields and vary in space when a current is applied thereto. More particularly, the gradient coils are designed to produce a magnetic field component that is aligned parallel to the main magnetic field, and which varies linearly in amplitude with the position along one of the axes x, y or z (with each pair of axes x, y and z being perpendicular). Thus, the combined effects of the magnetic fields imposed by the gradient coils make it possible to spatially encode each of the positions of the body intended to be probed.
The RF coil is intended to act as an RF transceiver. In particular, the RF coil is configured to emit RF energy pulses of a frequency equal to or close to the resonance frequency of the hydrogen nuclei spins and which is at least partially absorbed by these nuclei. As soon as the RF emission is interrupted, the nuclear spins relax in order to return to their initial energy state and in turn emit a RF signal capable of being collected by at least one RF coil. This RF signal is then processed using a computer and reconstruction algorithms in order to obtain an image of the body.
The imaging apparatus 1 according to the present invention forms a modular system. More particularly, the imaging apparatus 1 may comprise at least a first module 36 and a second module 37.
Each first module 36 from among F at least first module is in particular formed by the magnetic assembly 1A and a trolley 38. The trolley 38 may comprise castors.
The trolley 38 is in particular provided with a plate 39 on a face, called the upper face, of which the magnetic assembly 1A is attached. The trolley comprises two lateral walls 40 and 41 supporting, by one of their edge, called upper edge, the plate 39.
The two lateral walls 40 and 41 delimit, with the plate 39, a receiving space 42.
The second module 37 comprises a console, of essentially parallelepiped shape, supporting a set of electronic control elements of said apparatus, the console is in particular configured to be inserted into the receiving space 42. In this respect, the console can comprise casters allowing it to be inserted into the home space.
In particular, the lateral flanks 43 and 44 are in a sliding connection with, respectively, the side wall 40 and the side wall 41. In this respect, the apparatus may comprise A system of slide guides for sliding and locking the lateral flanks 43 and 44 against, respectively, the side wall 40 and the side wall 41. The slide system may in particular comprise one or two slides 45a, 45b. In this respect, one or two slides 45a, 45b are intended to cooperate with rails 46a and 46b arranged on both side walls 40 and 41. The rails 46a and 46b may also be provided with locking means making it possible to block the second module in the receiving space 42. Locking means may comprise shims 47a and 47b.
Finally, the imaging apparatus 1 also comprises connection means making it possible to connect the first module 36 and the second module 37. The connection means are in particular plug-in means which comprise a male plug 48 and a female plug 49 ([
Both modules of the console and the at least a first module comprise means for identifying, by the console, geometric and magnetic features of the magnetic assembly of said first module, the identification means being integrated into connection means of the console and of the first module. Identification means refers to means enabling the console to recognize the geometric and magnetic features of the magnetic assembly. This aspect in particular allows the console to recognize the configuration of the imaging apparatus.
Each of the male 48 and female 49 plugs, of complementary shape, may have a star shape ([
The identification function may involve digital means (for example a chip ID, e.g., RFID in the female plug and an ID reader in the second module), or analog means (for example a combination of resistors in the female plug, and an ammeter in the second module).
The male 48 and female 49 plugs comprise other ports associated with the RF coil controls and gradient coils.
Such a configuration makes the imaging apparatus 1 modular and makes it possible to consider different specific magnetic assemblies. In particular, it is possible according to the present invention to consider different magnetic assemblies, each magnetic assembly being intended to image a specific part of a body.
The invention relates to a method for manufacturing a magnetic assembly of an imaging apparatus 1 by magnetic resonance according to the present invention, said method comprising:
The method being characterized in that the number and the positioning the annular parts, as well as the amount of magnets forming each second plurality of magnets, are determined by the implementation of a genetic algorithm configured so that the resultant of the primary magnetic field and of the secondary magnetic field, called main field, in the analysis zone, has a second uniformity to be improved with respect to the first uniformity.
Of course, the invention is not limited to the described embodiments and variant embodiments may be envisaged without departing from the scope of the invention as defined by the claims.
Number | Date | Country | Kind |
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FR2113329 | Dec 2021 | FR | national |
Filing Document | Filing Date | Country | Kind |
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PCT/EP2022/084933 | 12/8/2022 | WO |