Malonamide derivatives

Abstract

The invention relates to malonamide derivatives of formula

Description

Claims

1. A compound of the general formula I

2. A compound of claim 1, wherein A1 is CH2, A2 is CO, R1 is hydrogen or lower alkyl.

3. A compound of claim 2, selected from the group consisting of

4. A compound of claim 2, selected from the group consisting of

5. A compound of claim 2, selected from the group consisting of

6. A compound of claim 1, wherein A1 is CH2, A2 is O—CO and R1 is hydrogen or lower alkyl.

7. A compound of claim 6, selected from the group consisting of

8. A compound of claim 1, wherein A1 is CHCF3, A2 is CO and R1 is hydrogen or lower alkyl.

9. A compound of claim 8, which is

10. A pharmaceutical composition comprising a compound of formula I