Material for dentistry

BACKGROUND OF THE INVENTION
(a) Field of the Invention
The present invention relates to a material for dentistry in which a specific (meth)acrylate compound is blended.
(b) Description of the Related Prior Art
In recent years, many materials for dentistry comprising synthetic polymers have been developed, and some of them take the form of compositions each comprising monomers, a polymerization initiator and other components which can be polymerized and cured when used. Examples of such compositions include (1) crown restoration materials such as chemically polymerizable and photopolymerizable composite resins and quick-curing resins (fast-polymerizable resins), (2) adhesive and transitory adhesives, for example, between a composite resin and a tooth, between a metal and a tooth, and between teeth, (3) chemically polymerizable and photopolymerizable pit and fissure sealants, (4) artificial crown materials such as thermally polymerizable and photopolymerizable hard crown resins, (5) transitory crown materials such as polycarbonate crowns and fast-setting resins for crowns, (6) denture plate materials such as thermally polymerizable, cold polymerizable (inclusive of casting type) and injection-moldable acrylic resins and adhesive denture plate reins, (7) restoration materials such as denture plate lining agents and restoration fast-setting resins, and (8) impression materials such as agar, alginates, polysulfide rubbers, silicone rubbers and (meth)acrylic impression materials.
Among these materials, for example, as the composite resin or the hard crown resin, there is used a blend of at least one monofunctional monomer, at least one polyfunctional monomer, an inorganic filler and a radical polymerization initiator, and as the crown resin, the sealant or the adhesive, there is used a combination of at least one monofunctional monomer, at least one polyfunctional monomer and a radical polymerization initiator. Furthermore, a restoration material such as the denture plate, the denture plate lining agent and the restoring quick polymerizable resin is required to be colorless and transparent, to be easily colored, to be aesthetic and to be excellent in workability, and therefore as this kind of restoration material, there is used a mixture of a polymer component (which is in the state of a powder in most cases) such as polymethyl methacrylate (hereinafter referred to as "PMMA") and polyethyl methacrylate (hereinafter referred to as "PEMA"), at least one monofunctional monomer, at least one polyfunctional monomer and a radical polymerization initiator.
Examples of the above-mentioned monofunctional monomer component include methyl methacrylate (MMA), ethyl methacrylate (EMA), butyl methacrylate (BMA), 2-hydroxyethyl methacrylate (HEMA) and H.sub.2 C.dbd.C(CH.sub.3)COOC.sub.2 H.sub.4 OCOC.sub.2 H.sub.5. Examples of the polyfunctional monomer component include 1,6-hexanediol dimethacrylate (HD), ethylene glycol dimethacrylate (1G), triethylene glycol dimethacrylate (3G), bisphenol A diglycidyl dimethacrylate (Bis-GMA), trimethylolpropane trimethacrylate (TMPT) and dipentaerythritol pentaacrylate (2P5A).
In addition, in Japanese Laid-open Patent Publication No. 1987-178502, a material for dentistry is described which contains, as the main component, a diester compound represented by CH.sub.2 .dbd.CR.sub.1 COOR.sub.2 OCOR.sub.3 (wherein R.sub.1 is a hydrogen atom or an alkyl group, R.sub.2 is an alkylene group and R.sub.3 is an alkyl group).
However, the composite resin, the hard crown resin, the quick-curing crown resin, the sealant and the adhesive are required to be (1) free from a strong foul odor, since they are directly put in a mouth. Furthermore, they are required to be free from irritation to a skin and a mucous membrane, since they are often brought into contact with dental pulp in pits of teeth. In addition, they must maintain strength under circumstances in a mouth, since they remain in the mouth for a long period of time after curing, and from this viewpoint, (3) polymers having high water absorption properties are inconvenient.
Moreover, the restoration materials such as the denture plate and the denture plate lining agent are required to be (1) free from a strong foul odor and (2) free from irritation to a skin and a mucous membrane, since they are manipulated by hands of a dentist or a dental technician, or since they are directly brought into contact with an oral mucous membrane for the sake of molding.
However, the above-mentioned monomers inconveniently cannot meet all of these requirements (1) to (3).
For example, monomers such as MMA, EMA, BMA, HEMA, HD, 1G, 3G, TMPT and 2P5A cannot meet the above-mentioned requirements (1) and (2), and monomers such as H.sub.2 C.dbd.C(CH.sub.3)COOC.sub.2 H.sub.4 OCOC.sub.2 H.sub.5 and Bis-GMA cannot meet the above-mentioned requirements (3). Even if these monomers are combined, all of the aforesaid requirements cannot be satisfied. Therefore, the development of a composition by which these problems are solved is desired.
The diester compounds described in the above Japanese Laid-open Patent Publication No. 1987-178502 are excellent in point of less stimulation, but they have perceptibly high water absorption properties. In consequence, their strength tends to deteriorate when they are used as dental materials, and what is worse, they are liable to color.
In the case of the above restoration material, a monomer component is mixed with a polymer component at a suitable ratio, and the mixture is then placed in a predetermined mold or put in a mouth for the sake of molding. Afterward, the material is taken out therefrom, and then polymerized at room temperature or under heating, thereby obtaining the restoration material. However, in the course of this molding, it is important that the material takes the state of the so-called dough stage for a suitable period of time. In short, the composition which is free from a strong foul odor and less irritant and which has a suitable period for dough stage is demanded.
SUMMARY OF THE INVENTION
In view of such situations, the present inventors have intensively researched to solve the above-mentioned problems, and as a result, they have found that in a material for dentistry comprising a composition of monomers and a radical polymerization initiator which will be polymerized and cured when used, the monomer components are specific (meth)acrylate monomers which are less odorous and less stimulative, the water absorption of a polymer made therefrom is low, and a suitable period for dough stage is present. Thus, the present invention has been achieved on the basis of such a knowledge.
That is, the gist of the present invention resides in a material for dentistry which is prepared by blending one or more monomers selected from the group consisting of a (meth)acrylate compound represented by the general, formula (1) ##STR2## (wherein R.sub.1 is a hydrogen atom or a methyl group, R.sub.2 is an alkylene group having 1 to 15 carbon atoms, and R.sub.3 is an alkyl group having 1 to 15 carbon atoms), a (meth)acrylate compound represented by the general formula (2) ##STR3## (wherein R.sub.4 is a hydrogen atom or a methyl group, R.sub.5 is an alkylene group having 1 to 15 carbon atoms, and R.sub.6 is an alkyl group having 1 to 15 carbon atoms), a (meth)acrylate compound represented by the general formula (3) ##STR4## (wherein R.sub.7 is a hydrogen atom or a methyl group, R.sub.8 is an alkylene group having 1 to 15 carbon atoms, R.sub.9 is an alkylene group having 1 to 10 carbon atoms, and R.sub.10 is an alkyl group having 1 to 15 carbon atoms), and a (meth)acrylate dimer represented by the formula (4), ##STR5##
The material for dentistry containing the specific (meth)acrylate compound according to the present invention is less odorous and less irritant and has a lower water absorption as compared with conventional materials, and when used as the restoration material, it has a suitable period for dough stage. That is, in the direct treatment of the interior in the mouth of a patient by the use of the above-mentioned material, the patient can get rid of discomforts such as odor and irritation, and the curable material itself can be used for a long period of time even under severe wet conditions in the mouth, because of a less water absorption and thus an excellent dimensional stability, and because of an excellent strength, a high color stability and a good durability. In addition, the material of the present case leads to improvements of safety and sanitation for a dentist or a dental technician, and operational efficiency.
Therefore, it is fair to say that the material of the present invention has a extremely high practical value in the dental field.

BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is an IR chart of a methacrylate obtained in Synthesis Example 1,
FIG. 2 is an IR chart of a methacrylate obtained in Synthesis Example 2, and
FIG. 3 is an IR chart of D-MMA obtained in Synthesis Example 3.

DETAILED DESCRIPTION OF THE INVENTION
Now, the present invention will be described mainly about cases where a material of the present case is used as restoration materials. However, the material for dentistry of the present invention should not be limited to the restoration materials but can be suitably used as dental composite resins, crown resins, dental sealant, dental adhesives and the like.
Any compound represented by the general formula (1) can be used, so long as in the formula, R.sub.1 is a hydrogen atom or a methyl group, R.sub.2 is an alkylene group having 1 to 15 carbon atoms, and R.sub.3 is an alkyl group having 1 to 15 carbon atoms. However, considering desired requirements of the material for dentistry such as a low odor, a low irritation, a low water absorption and a high mechanical strength of an obtained polymer, and a proper period for dough stage which is necessary in the case that the material is used as the binary restoration material, R.sub.2 in the general formula (1) is an alkylene group having 1 to 15 carbon atoms but it may be a straight-chain methylene group or polymethylene group or a polymethylene group having a side chain. The R.sub.2 group preferably has 1 to 7 carbon atoms. Furthermore, for the same reason, the R.sub.3 in the general formula (1) is an alkyl group preferably having 1 to 7 carbon atoms. Accordingly, examples of the (meth)acrylate compound which can be particularly preferably used in the present invention are as follows: ##STR6##
The (meth)acrylate compound represented by the above-mentioned general formula (1) of the present invention can be prepared from a specific unsaturated carboxylic acid [CH.sub.2 .dbd.C(R.sub.1)--COOH] or its acid halide and an ether alcohol (HO--R.sub.2 --O--R.sub.3) by an esterification reaction or alternatively by an ester exchange reaction between the unsaturated carboxylates.
Similarly, considering the desired requirements of the material for dentistry, the alkyl group represented by the R.sub.4 in the general formula (2) preferably has 1 to 7 carbon atoms, more preferably 1 to 4 carbon atoms. For the same reason, the R.sub.5 in the general formula (2) is an alkylene group but it may be a straight-chain methylene group or polymethylene group or a polymethylene group having a side chain. The R.sub.5 group preferably has 1 to 10 carbon atoms, more preferably 1 to 7 carbon atoms. Furthermore, for the same reason, the R.sub.6 in the general formula (2) is an alkyl group preferably having 1 to 10 carbon atoms, more preferably 1 to 7. Accordingly, examples of the (meth)acrylate compound represented by the general formula (2) which can be particularly preferably used in the present invention are as follows: ##STR7##
The (meth)acrylate compound represented by the above-mentioned general formula (2) regarding the present invention can be prepared by an esterification reaction between a specific unsaturated carboxylic acid [CH.sub.2 .dbd.C(R.sub.4)--COOH] or its acid halide and a keto-alcohol [HO--R.sub.5 --C(O)--R.sub.6 ] or alternatively by an ester exchange reaction between unsaturated carboxylates.
Similarly, considering the desired requirements of the material for dentistry, each of R.sub.8 and R.sub.9 in the general formula (3) is an alkylene group but it may be a straight-chain methylene group or polymethylene group or a polymethylene group having a side chain. R.sub.8 group preferably has 1 to 10 carbon atoms, more preferably 1 to 6 carbon atoms. For the same reason, R.sub.9 group preferably has 1 to 7 carbon atoms, more preferably 1 to 4 carbon atoms. Furthermore, for the same reason as described above, R.sub.10 in the general formula (3) is an alkyl group preferably having 1 to 10 carbon atoms, more preferably 1 to 7. On this account, typical examples of the (meth)acrylate compound represented by the general formula (3) which can be particularly preferably used in the present invention are as follows: ##STR8##
The (meth)acrylate compound represented by the above-mentioned general formula (3) regarding the present invention can be prepared by an esterification reaction between a specific unsaturated carboxylic acid [CH.sub.2 .dbd.C(R.sub.7)--COO--R.sub.8 --OCO--R.sub.9 --COOH] and an alkyl alcohol (R.sub.10 --OH), or alternatively by another reaction such as a reaction of an unsaturated alcohol [CH.sub.2 .dbd.C(R.sub.7)--COO--R.sub.8 --OH] and an ester group-containing carboxylic acid (HOCO--R.sub.9 --COO--R.sub.10), a reaction of an unsaturated carboxylic acid [CH.sub.2 .dbd.C(R.sub.7)--COOH] and an ester group-containing alcohol (HO--R.sub.8 --OOC--R.sub.9 --COO--R.sub.10), a reaction in which the above-mentioned carboxylic acid is replaced with a carboxylic acid halide, or an ester exchange reaction between unsaturated carboxylates.
On the other hand, the methacrylate dimer represented by the general formula (4) regarding the present invention can be prepared by heating methyl methacrylate at a high temperature in the presence of a polymerization inhibitor or alternatively by fractionating a by-product formed at the time of the manufacture of methyl methacrylate.
In manufacturing the material for dentistry of the present invention, a combination of one or more kinds of monomers selected only from the above-mentioned group can be used, but it is also possible to blend another monomer component therewith, if necessary, which is polymerizable with the specific (meth)acrylate compound represented by the general formula (1), (2) or (3) or the specific methacrylate dimer represented by the formula (4), so long as the low odor and the low irritation can be maintained.
Typical examples of such another kind of monomer include 2-ethylhexyl (meth)acrylate, lauryl (meth)acrylate, tridecyl (meth)acrylate, stearyl (meth)acrylate, cyclohexyl (meth)acrylate, n-hexyl (meth)acrylate, tetrahydrofurfuryl (meth)acrylate, ethylene glycol di(meth)acrylate, diethylene glycol di(meth)acrylate, triethylene glycol, di(meth)acrylate, tetraethylene glycol di(meth)acrylate, pentaethylene glycol di(meth)acrylate, hexaethylene glycol di(meth)acrylate, heptaethylene glycol di(meth)acrylate, octaethylene glycol di(meth)acrylate, nonaethylene glycol di(meth)acrylate, 1,3-butylene glycol di(meth)acrylate, propylene glycol di(meth)acrylate, 1,3-butanediol di(meth)acrylate, 1,4-butanediol di(meth)acrylate, 1,5-pentanediol di(meth)acrylate, 1,6-hexanediol di(meth)acrylate, 1,7-heptanediol di(meth)acrylate, 1,8-octanediol di(meth)acrylate, 1,9-nonanediol di(meth)acrylate, 1,10-decanediol di(meth)acrylate, neopentyl glycol di(meth)acrylate, 2,2-bis(4-methacryloyloxyphenyl)propane, 2,2-bis(4-methacryloyloxyethoxyphenyl)propane, 2,2-bis(4-methacryloyloxypolyethoxyphenyl)propane, 2,2-bis[4-(3-methacryloyloxy-2-hydroxypropoxy)phenyl]propane, di(methacryloyloxyethyl)trimethylhexamethylenediurethane, tetramethylolmethane tri(meth)acrylate, trimethylolpropane tri(meth)acrylate, trimethylolethane tri(meth)acrylate and tetramethylolmethane tetra(meth)acrylate. They can be used singly or in combination. Above all, polyfunctional methacrylates such as ethylene glycol dimethacrylate, triethylene glycol dimethacrylate, 1,6-hexanediol dimethacrylate, 2,2-bis(4-methacryloyloxyethoxyphenyl)propane, neopentyl glycol dimethacrylate and trimethylolpropane trimethacrylate are preferable as the other copolymerizable monomer, components in view of mechanical strength of cured materials which will be obtained.
The blend ratio of the (meth)acrylate compound represented by the general formula (1), (2) or (3) or D-MMA to the above-mentioned other copolymerizable monomer component depends upon the degree of the irritation of the other copolymerizable monomer component, and usually it can be selected suitably, so long as odor and irritation are maintained at a low level. Nevertheless, the above-mentioned blend ratio is such that the amount of the (meth)acrylate compound represented by the general formula (1), (2) or (3) or D-MMA is preferably not less than 20% by weight, more preferably not less than 30% by weight.
In the case that the material for dentistry of the present invention is used as a restoration material, an organic polymer may be used which can be dissolved or swelled in the above-mentioned monomer. Typical examples of the organic polymer include polymethyl methacrylate (PMMA), polyethyl methacrylate (PEMA), MMA/EMA copolymer, MMA/BMA copolymer, polystyrene, polybutyl methacrylate, MMA/styrene copolymer, EMA/BMA copolymer, EMA/styrene copolymer, polyacrylonitrile, styrene/acrylonitrile copolymer, styrene/acrylonitrile/butadiene copolymer, polycarbonate resin, polyvinyl chloride, polyacrylates, polymethacrylates, polyester resins, polyethylene, resin, polypropylene resin, silicone resins and fluorine-containing resin. Above all, preferable are PMMA, PEMA, MMA/EMA copolymer, MMA/BMA copolymer, polystyrene, polybutyl methacrylate, MMA/styrene copolymer, EMA/BMA copolymer, EMA/styrene copolymer, and mixtures of these polymers and other polymers, because they have a particularly proper solubility.
Any particular restriction is not put on the molecular weight and the average particle diameter of this kind of polymer, but considering its solubility in the monomer component of the present invention and swell characteristics and mechanical strength of cured materials which will be obtained therefrom, the molecular weight of the polymer is preferably from 10,000 to 1,500,000, more preferably from 50,000 to 1,000,000, and the particle diameter of the polymer is preferably from 1 to 150 .mu.m, more preferably from 10 to 100 .mu.m.
The blend ratio of the polymer component to all the monomer components can be selected from an extensive range, but in view of the mechanical strength of the cured articles and the like, the amount of all the monomer components with respect to 10 parts by weight of the polymer component is preferably from 1 to 140 parts by weight (in other words, from 7.1 to 1,000 parts by weight with respect to 100 parts by weight of all the, monomers), more preferably from 2 to 110 parts by weight, most preferably from 4 to 85 parts by weight.
As a polymerization initiator used to obtain composite resins and restoration materials and as a curing agent used in the adhesive, there can be employed known compounds. In the case that heat curing is carried out, a substance which can thermally decompose and then initiate polymerization is used. Examples of such a substance include benzoyl peroxide, cumene hydroperoxide, t-butyl hydroperoxide, dicumyl peroxide, acetyl peroxide, lauroly peroxide and azobisisobutyronitrile. Furthermore, in the case that polymerization/curing is carried out at ordinary temperature, there can be used, for example, a combination of a peroxide and an amine, a peroxide and a sulfinic acid, or a peroxide and a cobalt compound. When the polymerization initiators are used in combination, the composition may be divided into two parts, and one part of the composition may be blended with the peroxide and the other part may be blended with the amine, the sulfinic acid or the cobalt compound. The amount of the above-mentioned curing agent is preferably from 0.01 to 15% by weight, more preferably from 0.05 to 10% by weight, most preferably from 0.1 to 7% by weight with respect to the amount of the total monomers.
In the case that polymerization/curing is carried out by means of the irradiation of ultraviolet light, or visible light, any of known photosensitizers can be used. Examples of the suitable photosensitizer include benzoin alkyl ethers such as benzoin methyl ether, benzoin ethyl ether and benzoin propyl ether, .alpha.-diketones such as benzil, biacetyl and camphorquinone, and benzophenones such as benzophenone and methoxybenzophenone. When the above-mentioned photocuring means is employed, a reducing agent can be used in addition to the photosensitizer. Examples of the suitable reducing agent include amines such as aminobenzoic acid ester, toluidine, benzylamine and amino methacrylate.
The amount of the photocuring agent to be used is preferably from 0.01 to 15% by weight, more preferably from 0.05 to 10% by weight, most preferably from 0.1 to 7% by weight.
In the present invention, an inorganic filler can be additionally blended with the above-mentioned monomers, polymer component and polymerization/curing agent. Typical examples of the inorganic filler include oxides, hydroxides, chlorides, sulfates, sulfites, carbonates, phosphates, silicates and borates of elements in the groups I, II, III and IV of the periodic table and transition metals, mixtures thereof, and composite salts thereof. Typical examples of the inorganic filler include silicon dioxide, quartz powder, aluminum oxide, titanium oxide, barium sulfate, talc, glass powder, glass beads, glass fiber, a glass filler containing a barium salt or a strontium salt, silica gel, colloidal silica, carbon fiber, zirconium oxide, tin oxide and ceramic powder. The filler may be an untreated filler, a filler the surface of which is treated with a silane coupling agent or a titanate coupling agent, a filler coated with a polymer, or a filler composite containing an organic material prepared by the process described in Japanese Laid-open Patent Publication No. 1985-81116.
The amount of the filler is preferably from 0.1 to 630% by weight (6.3 times), more preferably from 1 to 570% by weight, most preferably from 10 to 460% by weight with respect to the amount of the total monomers.
As a molding method, any of known molding techniques can be utilized which are compression molding, cast molding and injection molding.
In the material for dentistry of the present invention, a colorant, a polymerization inhibitor, an ultraviolet absorber, an oxidation stabilizer and the like can be further blended, if necessary.
The material for dentistry of the present invention can also be used as a dental material other than the restoration material.
For example, the material for dentistry can, be utilized as an adhesive or a sealant, which can be prepared from the (meth)acrylate compound represented by the general formula (1), (2) or (3) or D-MMA of the present invention, the same other monomer component copolymerizable with this compound as in the case of the above-mentioned restoration material, a polymerization initiator, and if necessary, a polymer, an inorganic filler, a colorant, a polymerization inhibitor, an ultraviolet absorber, an oxidation stabilizer and the like.
In addition, the material for dentistry of the present invention can also be utilized as a composite resin, a hard crown resin or a quick-curing crown resin, which can be prepared from the (meth)acrylate compound represented by the general formula (1), (2) or (3) or D-MMA of the present invention, the same other monomer component copolymerizable with this compound as in the case of the above-mentioned restoration material, a polymerization initiator, an inorganic filler, and the like. This inorganic filler is the same as used in the restoration material. If necessary, a polymer, a colorant, a polymerization inhibitor, an ultraviolet absorber, an oxidation stabilizer and the like can also be blended therewith.
Now, the present invention will be described in reference to examples.
The (meth)acrylate compound of the present invention 5 is not different at all from a conventional (meth)acrylate monomer for dentistry in point of reactivity except for being less odorous and less irritant.
Thus, in the following examples, reference will be made mainly to embodiments of restoration materials.
EXAMPLES 1 TO 8 AND COMPARATIVE EXAMPLES 1 to 4
As specific (meth)acrylate compounds represented by the general formula (1) according to the present invention, the following compounds were used, and an odor test, an irritation test and a polymer solubility test were then carried out. ##STR9##
Procedures of the respective tests will be briefly described hereinafter, and the results of the tests will be set forth together in Table 1.
Odor Test
Five unspecified testers aged 20 to 30 were selected, and the odor test was carried out in accordance with the following evaluation criterion by them. When the testers had different evaluations, the test was repeated again, until three or more of the testers had the same evaluation.
Evaluation Criterion
.largecircle.. . . faintly odorous
.DELTA.. . . weakly odorous
X. . . strongly odorous
Irritation Test
Five unspecified testers aged 20 to 30 were selected. One drop of a sample was dropped on the tongue tip of each tester, and after one minute, evaluation was made on the basis of the pain of the tongue tip in accordance with the following evaluation criterion.
Evaluation Criterion
.largecircle.. . . little painful
.DELTA.. . . slightly painful
X. . . very painful
Polymer Solubility Test
A polyethyl methacrylate powder having an average molecular weight of 230.times.10.sup.3 and an average particle diameter of 25 .mu.m was mixed with a (meth)acrylate compound used in the present invention so as to be a concentration of 20% by weight, and the mixture was then stirred. After 5 hours, evaluation was made in accordance with the following evaluation criterion by observing the state of each mixture.
Evaluation Criterion
S. . . soluble
SW. . . swelled
IS. . . insoluble
TABLE 1______________________________________ Irri- Polymer Odor tation Solubility Compound Test Test Test______________________________________Example 1 A .largecircle.-.DELTA. .DELTA. SExample 2 B .largecircle.-.DELTA. .largecircle. SExample 3 C .largecircle. .largecircle. SExample 4 D .largecircle. .largecircle. SWExample 5 E .DELTA. .largecircle. SExample 6 F .largecircle.-.DELTA. .DELTA. SExample 7 G .largecircle. .largecircle. SWExample 8 H .largecircle. .largecircle. SWComp. methyl X X SEx. 1 methacrylateComp. ethyl X X SEx. 2 methacrylateComp. iso-propyl X X SWEx. 3 methacrylateComp. iso-butyl X .DELTA. SWEx. 4 methacrylate______________________________________
EXAMPLES 9 TO 19
The same procedure as in Example 2 was effected except that mixtures of monomers were used as test compounds. The results are set forth in Table 2.
TABLE 2 (I)______________________________________ Mixture of Monomers I II______________________________________Example 9 Compound B cyclohexyl methacrylateExample 10 " lauryl methacrylateExample 11 " tridecyl methacrylateExample 12 " ethylene glycol dimethacrylateExample 13 " triethylene glycol dimethacrylateExample 14 " 1,6-hexanediol dimethacrylateExample 15 " 2,2-bis(4-metha- cryloyloxyethoxy- phenyl)propaneExample 16 " neopentyl glycol dimethacrylateExample 17 " trimethylolpropane trimethacrylateExample 18 " 1,6-hexanediol dimethacrylateExample 19 " 1,6-hexanediol dimethacrylate______________________________________
TABLE 2 (II)______________________________________ Mixing Weight Irri- Polymer Ratio Odor tation Solubility (I/II) Test Test Test______________________________________Example 9 70/30 .DELTA. .largecircle. SExample 10 " .largecircle. .largecircle. SExample 11 " .largecircle. .largecircle. SExample 12 " .largecircle. .largecircle. SExample 13 " .largecircle. .largecircle. SExample 14 " .largecircle. .largecircle. SExample 15 " .largecircle. .largecircle. SExample 16 " .largecircle. .largecircle. SExample 17 " .largecircle. .largecircle. SExample 18 50/50 .largecircle. .largecircle. SExample 19 40/60 .largecircle. .largecircle. S______________________________________
EXAMPLES 20 TO 26, COMPARATIVE EXAMPLES 5 AND 6
In each monomer solution shown in Table 3 was dissolved 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide, and the solution was then placed in a glass tube and the latter was sealed up. Afterward, the glass tube was heated at 60.degree. C. for 24 hours, and successively it was further heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for each cured product, performance was evaluated by the following procedure, and the results are set forth in Table 3.
Performance Evaluation of Cured Product
Indirect Tensile (Diametral) Strength
Each test piece was molded into the form of a 6.times.6 mm.phi. cylinder. An indirect tensile test was employed in which there was utilized the phenomenon that tensile stress was produced at right angles to compressive force by applying the compressive force in a diameter direction of the cylindrical test piece. The tensile strength was calculated in accordance with the following formula:
Tensile strength=(2.times.C)/(.pi..times.D.times.L)
C=compression load,
D=diameter of the test piece, and
L=length of the test piece.
Amount of Absorbed Water
Each test piece was molded into the form of a 10.times.1 mm.phi. cylinder. The test piece was immersed in water at 37.degree. C. for 7 days, and an amount of absorbed water per unit area of the test piece was then measured.
TABLE 3__________________________________________________________________________ Amount of Indirect Tensile Absorbed Water Monomer Solution Strength (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 20 Compound B 275 0.51Example 21 Compound D 230 0.45Example 22 Compound F 262 0.50Example 23 Compound A/Compound B = 280 0.55 30/70 (weight ratio)Example 24 Compound A/Compound B = 288 0.57 70/30Example 25 Compound B/1,6-hexane- 375 0.58 diol dimethacrylate = 50/50Example 26 Compound B/tri- 408 0.58 methylolpropane trimethacrylate = 50/50Comp. Ex. 5 butyl methacrylate 188 0.98Comp. Ex. 6 ##STR10## 270 1.02__________________________________________________________________________
EXAMPLES 27 TO 37
Each polymer powder shown in Table 4 was mixed with a monomer solution at a weight ratio of 30/70 in which 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide was dissolved, and the mixture was then placed in a glass tube. The latter was then sealed up and heated at 60.degree. C. for 24 hours and successively heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for the thus cured product, performance was evaluated by the same procedure as in Example 20. The results are set forth in Table 4.
TABLE 4__________________________________________________________________________ Indirect Amount of Tensile AbsorbedComposition of Powder-Solution Mixture Strength WaterPolymer Powder Monomer Solution (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 27 PMMA (*1) Compound A 301 0.59Example 28 PEMA (*2) " 270 0.55Example 29 methyl methacrylate/ " 285 0.57 ethyl methacrylate copolymer (*3)Example 30 methyl methacrylate/ " 265 0.58 butyl methacrylate copolymer (*4)Example 31 polystyrene (*5) " 286 0.52Example 32 polybutyl methacrylate " 250 0.56 [PBMA] (*6)Example 33 methyl methacrylate/ " 295 0.57 styrene copolymer (*7)Example 34 ethyl methacrylate/ " 255 0.56 butyl methacrylate copolymer (*8)Example 35 ethyl methacrylate/ " 280 0.54 styrene copolymer (*9)Example 36 PMMA/PEMA = 50/50 " 279 0.57 (weight ratio)Example 37 PEMA/PBMA = 50/50 " 242 0.56 (weight ratio)__________________________________________________________________________
Properties of Polymers
The abbreviations, MW, PS and CP mean an average molecular weight, an average particle diameter and a composition of each copolymer, respectively.
(*1) MW: 480.times.10.sup.3, PS: 15 .mu.m
(*2) MW: 230.times.10.sup.3, PS: 25 .mu.m
(*3) CP: 40/60, MW: 320.times.10.sup.3, PS: 20 .mu.m
(*4) CP: 40/60, MW: 60.times.10.sup.3, PS: 23 .mu.m
(*5) MW: 120.times.10.sup.3, PS: 30 .mu.m
(*6) MW: 360.times.10.sup.3, PS: 42 .mu.m
(*7) CP: 75/25, MW: 85.times.10.sup.3, PS:84 .mu.m
(*8) CP: 50/50, MW: 780.times.10.sup.3, PS: 12 .mu.m
(*9) CP: 50/50, MW: 520.times.10.sup.3, PS: 18 .mu.m
EXAMPLES 38 TO 40
Each PEMA powder having an average particle diameter shown in Table 5 (average molecular weight=230.times.10.sup.3) was mixed with a monomer mixture comprising compound B/1,6-hexanediol dimethacrylate=36/64 (weight ratio) at a weight ratio of 2:1, and for the resulting mixture, a period for dough stage was then measured by the following test procedure. The results are set forth in Table 5.
Test Procedure of Period for Dough Stage
Predetermined amounts of a polymer powder and a monomer solution are weighed in a weighing bottle (inner diameter 47 mm, height 2 cm), and after stirring for 20 seconds, the weighing bottle is covered with a lid of reinforced glass, followed by allowing the bottle to stand for 5 minutes. After stirring for 20 seconds again, the weighing bottle is covered with the reinforced glass lid and then allowed to stand for 5 minutes. The starting point of the period for dough stage is when it has been confirmed by touching the surface of the sample with a finger that the sample is not tacky any more. The sample is then separated from the wall surface of the weighing bottle by moving a metallic needle along the inside wall of the bottle. The end point of the period for dough stage is when the sample is inverted by piercing the stem of a spoon into the sample. A pot life is obtained from the formula of (the end point of the period for dough stage)-(the starting point of the period for dough stage).
TABLE 5______________________________________Average Diameter Period forof PEMA Powder Dough Stage (min)(.mu.m) End Start Pot Life______________________________________Example 38 95 77 24 53Example 39 84 69 22 47Example 40 78 46 20 26______________________________________
SYNTHESIS EXAMPLE 1 ##STR11##
In a 500-milliliter four-necked flask equipped with a condenser tube, a nitrogen-introducing pipe, a stirring rod and a thermocouple were placed 1 mole of methacrylic acid as an unsaturated carboxylic acid, 0.8 mole of thionyl chloride, a small amount of hydroquinone and 10 drops of DMF (dimethylformamide) as a catalyst, and they were then mixed and reacted for 15 hours in a water bath. Afterward, 0.8 mole of 4-hydroxy-2-butanone(.gamma.-ketobutanol) was added to the reaction solution, and reaction was then carried out at a temperature of from 40.degree. to 50.degree. C. for 3 hours. The reaction solution was dispersed in an excessive amount of water, and the resulting dispersion was then extracted with 400 ml of methylene chloride and the extract (the methylene chloride solution) was separated, washed with 300 ml of water twice, neutralized with sodium bicarbonate, washed, and acidified with hydrochloric acid. Anhydrous magnesium sulfate was added to the methylene chloride solution, and the solution was then dehydrated, followed by filtration. The solvent in the filtrate was vaporized under reduced pressure by the use of an aspirator, and finally the solvent was removed therefrom at 50.degree. C. for 30 minutes, so that the desired specific methacrylate compound was obtained.
In this case, the yield of the thus obtained compound was about 50 g. The IR chart of this compound is shown in FIG. 1. Other compounds represented by the general formula (2) could be synthesized by the same procedure as described above.
EXAMPLES 41 TO 45
The following compounds were used as specific (meth)acrylate compounds represented by the general formula (2) according to the present invention, and an odor test, an irritation test and a polymer solubility test were carried out in the same procedure as in Example 1. ##STR12##
The results are set forth in Table 6.
TABLE 6______________________________________ Irri- Polymer Odor tation Solubility Compound Test Test Test______________________________________Example 41 I .largecircle.-.DELTA. .largecircle.-.DELTA. SExample 42 J .largecircle.-.DELTA. .largecircle. SExample 43 K .largecircle. .largecircle. SExample 44 L .largecircle. .largecircle. SExample 45 M .largecircle. .largecircle. SComp. Ex. 1 methyl X X S methacrylateComp. Ex. 2 ethyl X X S methacrylateComp. Ex. 4 isobutyl X .DELTA. SW methacrylate______________________________________
EXAMPLES 46 TO 56
The same procedure as in Example 43 was effected except that compounds for tests were mixtures of monomers, and the results are set forth in Table 7.
TABLE 7 (I)______________________________________ Mixture of Monomers I II______________________________________Example 46 Compound K cyclohexyl methacrylateExample 47 " lauryl methacrylateExample 48 " tridecyl methacrylateExample 49 " ethylene glycol dimethacrylateExample 50 " triethylene glycol dimethacrylateExample 51 " 1,6-hexanediol dimethacrylateExample 52 " neopentyl glycol dimethacrylateExample 53 " 2,2-bis(4- methacryloxy- phenyl)propaneExample 54 " trimethylolpropane trimethacrylateExample 55 " 1,6-hexanediol dimethacrylateExample 56 " 1,6-hexanediol dimethacrylate______________________________________
TABLE 7 (II)______________________________________ Mixing Weight Irri- Polymer Ratio Odor tation Solubility (I/II) Test Test Test______________________________________Example 46 70/30 .largecircle.-.DELTA. .largecircle. SExample 47 " .largecircle. .largecircle. SExample 48 " .largecircle. .largecircle. SExample 49 " .largecircle. .largecircle. SExample 50 " .largecircle. .largecircle. SExample 51 " .largecircle. .largecircle. SExample 52 " .largecircle. .largecircle. SExample 53 " .largecircle. .largecircle. SExample 54 " .largecircle. .largecircle. SExample 55 50/50 .largecircle. .largecircle. SExample 56 40/60 .largecircle. .largecircle. S______________________________________
EXAMPLES 57 TO 62
In each monomer solution shown in Table 8 was dissolved 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide, and the solution was then placed in a glass tube and the latter was sealed up. Afterward, the glass tube was heated at 60.degree. C. for 24 hours, and successively it was further heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for each cured product, performance was evaluated by the same procedure as in Example 20, and the results are set forth in Table 8.
TABLE 8__________________________________________________________________________ Amount of Indirect Tensile Absorbed Water Monomer Solution Strength (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 57 Compound J 248 0.52Example 58 Compound K 260 0.48Example 59 Compound M 256 0.49Example 60 Compound J/Compound K = 267 0.58 30/70 (weight ratio)Example 61 Compound J/Compound K = 252 0.57 70/30 (weight ratio)Example 62 Compound K/1,6-hexane- 348 0.58 diol dimethacrylate = 50/50 (weight ratio)Comp. Ex. 5 isobutyl methacrylate 188 0.98Comp. Ex. 6 ##STR13## 270 1.02__________________________________________________________________________
EXAMPLES 63 TO 73
Each polymer powder shown in Table 9 was mixed with a monomer solution at a weight ratio of 30/70 in which 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide was dissolved, and the mixture was then placed in a glass tube. The latter was then sealed up and heated at 60.degree. C. for 24 hours and successively heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for the thus cured product, performance was evaluated by the same procedure as in Example 58. The results are set forth in Table 9.
In this connection, properties of the polymer powders used in these examples were the same as in Examples 27 to 37.
TABLE 9__________________________________________________________________________ Indirect Amount of Tensile AbsorbedComposition of Powder-Solution Mixture Strength WaterPolymer Powder Monomer Solution (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 63 PMMA (*1) Compound K 250 0.57Example 64 PEMA (*2) " 270 0.57Example 65 methyl methacrylate/ " 276 0.60 ethyl methacrylate copolymer (*3)Example 66 methyl methacrylate/ " 261 0.55 butyl methacrylate copolymer (*4)Example 67 polystyrene (*5) " 244 0.58Example 68 polybutyl methacrylate " 268 0.63 [PBMA] (*6)Example 69 methyl methacrylate/ " 250 0.60 styrene copolymer (*7)Example 70 ethyl methacrylate/ " 239 0.59 butyl methacrylate copolymer (*8)Example 71 ethyl methacrylate/ " 235 0.53 styrene copolymer (*9)Example 72 PMMA/PEMA = 50/50 " 252 0.59 (weight ratio)Example 73 PEMA/PBMA = 50/50 " 238 0.57 (weight ratio)__________________________________________________________________________
EXAMPLES 74 TO 76
Each PEMA powder having an average particle diameter shown in Table 10 (average molecular weight=230.times.10.sup.3) was mixed with a monomer mixture comprising Compound J/1,6-hexanediol dimethacrylate=36/64 (weight ratio) at a ratio of 2:1, and for the resulting mixture, a dough stage time was then measured by the same procedure as in Example 38. The results are set forth in Table 10.
TABLE 10______________________________________ Average Diameter of PEMA Powder Dough Stage Time (min) (.mu.m) End Start Pot Life______________________________________Example 74 84 64 13 51Example 75 52 45 15 30Example 76 25 31 16 15______________________________________
SYNTHESIS EXAMPLE 2 ##STR14##
In a 2,000-milliliter four-necked flask equipped with a cooling pipe, a nitrogen-introducing pipe, a stirring rod and a thermocouple was placed 115 g of the acrylic ester SA [CH.sub.2 .dbd.C(CH.sub.3)COOC.sub.2 H.sub.4 OCOC.sub.2 H.sub.4 COOH)] made by Mitsubishi Rayon Co., Ltd. as an unsaturated carboxylic acid, 500 ml of methanol, 2.5 g of concentrated hydrochloric acid and a small amount of hydroquinone, and they are mixed, Afterward, the mixture was allowed to stand at room temperature (abut 20.degree. C.) for 3 days. Next, 500 ml of water was added to the mixture to dilute it and then extracted with 200 ml of methylene chloride twice, and the extract was washed with 300 ml of water twice and with an aqueous saturated sodium hydrogen carbonate solution once, and dried over anhydrous magnesium sulfate, followed by filtration. The solution was concentrated under reduced pressure by the use of an aspirator, and finally, the solvent was distilled off at 50.degree. C for 30 minutes, so that the desired specific methacrylate compound was obtained. In this case, the yield of the thus obtained compound was about 100.1 g. The IR chart of this product is shown in FIG. 2.
Other compounds represented by the general formula (3) could be synthesized in accordance with the similar reaction by the use of a suitable unsaturated carboxylic acid and an alcohol.
EXAMPLES 77 TO 81
The following compounds were used as typical (meth)acrylate compounds represented by the general formula (3) according to the present invention, and an odor test, an irritation test and a polymer solubility test were carried out in the same procedure as in Example 1. ##STR15##
TABLE 11______________________________________ Irri- Polymer Odor tation Solubility Compound Test Test Test______________________________________Example 77 N .largecircle.-.DELTA. .largecircle.-.DELTA. SExample 78 P .largecircle. .largecircle. SExample 79 Q .largecircle. .largecircle. SWExample 80 R .largecircle. .largecircle. SExample 81 S .largecircle. .largecircle. SWComp. Ex. 1 methyl X X S methacrylateComp. Ex. 2 ethyl X X S methacrylateComp. Ex. 4 isobutyl X .DELTA. SW methacrylate______________________________________
EXAMPLES 82 TO 92
The same procedure as in Example 78 was effected except that compounds for tests were mixtures of monomers, and the results are set forth in Table 12.
TABLE 12 (I)______________________________________Mixture of Monomers______________________________________Example 82 Compound P cyclohexyl methacrylateExample 83 " lauryl methacrylateExample 84 " tridecyl methacrylateExample 85 " ethylene glycol dimethacrylateExample 86 " triethylene glycol dimethacrylateExample 87 " 1,6-hexanediol dimethacrylateExample 88 " neopentyl glycol dimethacrylateExample 89 " 2,2-bis(4-meth- acryloyloxyethoxy- phenyl)propaneExample 90 " trimethylolpropane trimethacrylateExample 91 " 1,6-hexanediol dimethacrylateExample 92 " 1,6-hexanediol dimethacrylate______________________________________
TABLE 12 (II)______________________________________ Mixing Weight Irri- Polymer Ratio Odor tation Solubility (I/II) Test Test Test______________________________________Example 82 70/30 .largecircle.-.DELTA. .largecircle. SExample 83 " .largecircle. .largecircle. SExample 84 " .largecircle. .largecircle. SExample 85 " .largecircle. .largecircle. SExample 86 " .largecircle. .largecircle. SExample 87 " .largecircle. .largecircle. SExample 88 " .largecircle. .largecircle. SExample 89 " .largecircle. .largecircle. SExample 90 " .largecircle. .largecircle. SExample 91 50/50 .largecircle. .largecircle. SExample 92 40/60 .largecircle. .largecircle. S______________________________________
EXAMPLES 93 TO 98
In each monomer solution shown in Table 13 was dissolved 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide, and the solution was then placed in a glass tube and the latter was sealed up. Afterward, the glass tube was heated at 60.degree. C. for 24 hours, and successively it was further heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for each cured product, performance was evaluated by the same procedure as in Example 20, and the results are set forth in Table 13.
TABLE 13__________________________________________________________________________ Amount of Indirect Tensile Absorbed Water Monomer Solution Strength (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 93 Compound N 260 0.73Example 94 Compound P 278 0.69Example 95 Compound S 254 0.62Example 96 Compound N/Compound P = 281 0.68 30/70 (weight ratio)Example 97 Compound N/Compound P = 275 0.67 70/30 (weight ratio)Example 98 Compound P/1,6-hexane- 345 0.75 diol dimethacrylate = 50/50 (weight ratio)Comp. Ex. 5 isobutyl methacrylate 188 0.98Comp. Ex. 6 ##STR16## 270 1.02__________________________________________________________________________
EXAMPLES 99 TO 109
Each polymer powder shown in Table 14 was mixed with a monomer solution at a weight ratio of 30/70 in which 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide was dissolved, and the mixture was then placed in a glass tube. The latter was then sealed up and heated at 60.degree. C. for 24 hours and successively heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for the thus cured product, performance was evaluated by the same procedure as in Example 94. The results are set forth in Table 14.
In this connection, properties of the polymer powders used in these examples were the same as in Examples 27 to 37.
TABLE 14__________________________________________________________________________ Indirect Amount of Tensile Absorbed Composition of Powder-Solution Mixture Strength Water Polymer Powder Monomer Solution (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 99 PMMA (*1) Compound P 264 0.68Example 100 PEMA (*2) " 299 0.66Example 101 methyl methacrylate/ " 304 0.71 ethyl methacrylate copolymer (*3)Example 102 methyl methacrylate/ " 270 0.65 butyl methacrylate copolymer (*4)Example 103 polystyrene (*5) " 258 0.70Example 104 polybutyl methacrylate " 286 0.75 (PBMA) (*6)Example 105 methyl methacrylate/ " 267 0.69 styrene copolymer (*7)Example 106 ethyl methacrylate/ " 280 0.68 butyl methacrylate copolymer (*8)Example 107 ethyl methacrylate/ " 261 0.62 styrene copolymer (*9)Example 108 PMMA/PEMA = 50/50 " 260 0.68 (weight ratio)Example 109 PEMA/PBMA = 50/50 " 268 0.66 (weight ratio)__________________________________________________________________________
EXAMPLES 110 TO 112
Each PEMA powder having an average particle diameter shown in Table 15 (average molecular weight=230.times.10.sup.3) was mixed with a monomer mixture comprising Compound P/1,6-hexanediol dimethacrylate=36/64 (weight ratio) at a ratio of 2:1, and for the resulting mixture, a period for dough stage was then measured by the same procedure as in Example 38. The results are set forth in Table 15.
TABLE 15______________________________________ Average Diameter Period for of PEMA Powder Dough Stage (min) (.mu.m) End Start Pot Life______________________________________Example 110 84 75 22 53Example 111 52 49 19 30Example 112 25 36 18 18______________________________________
SYNTHESIS EXAMPLE 3 ##STR17##
In a 1-liter stainless steel autoclave were placed 400 g of methyl methacrylate and 2 g of hydroquinone. Next, the atmosphere in the reactor was replaced with an N.sub.2 gas several times, and the reactor was then sealed up. Afterward, the reactor was heated at 225.degree. C. for 12 hours to carry out a thermal dimerization reaction.
The component having a boiling point of 107.degree. C. (7 mmHg) in the reaction product was fractionated, and as a result, 90.5 g of a colorless and transparent liquid was obtained. Properties of this component were as follows:
specific gravity: 1.0397 g/cm.sup.3 (25.degree. C.)
.eta..sup.25.sub.D : 1.4488
.eta.: 4.09 cp (25.degree. C.)
It was confirmed from a literature [J. Am. Chem. Soc., 78, 472 (1956)] that the above component was the desired D-MMA. The infrared absorption spectrum of the desired product is shown in FIG. 3.
EXAMPLE 113
A specific methacrylate dimer (D-MMA) of the present invention was used, and an odor test, an irritation test and a polymer solubility test were carried out in the same procedure as in Example 1.
The results are set forth in Table 16.
TABLE 16______________________________________ Irri- Polymer Odor tation Solubility Compound Test Test Test______________________________________Example 113 D-MMA .largecircle.-.DELTA. .largecircle.-.DELTA. SComp. Ex. 1 methyl X X S methacrylateComp. Ex. 2 ethyl X X S methacrylateComp. Ex. 4 isobutyl X .DELTA. SW methacrylate______________________________________
EXAMPLES 114 TO 124
The same procedure as in Example 113 was effected except that compounds for tests were mixtures of monomers, and the results are set forth in Table 17.
TABLE 17 (I)______________________________________Mixture of Monomers______________________________________Example 114 Compound D-MMA cyclohexyl methacrylateExample 115 " lauryl methacrylateExample 116 " tridecyl methacrylateExample 117 " ethylene glycol dimethacrylateExample 118 " triethylene glycol dimethacrylateExample 119 " 1,6-hexanediol dimethacrylateExample 120 " neopentyl glycol dimethacrylateExample 121 " 2,2-bis(4-meth- acryloxyethoxy- phenyl)propaneExample 122 " trimethylolpropane trimethacrylateExample 123 " 1,6-hexanediol dimethacrylateExample 124 " 1,6-hexanediol dimethacrylate______________________________________
TABLE 17 (II)______________________________________ Mixing Weight Stimu- Polymer Ratio Odor lation Solubility (I/II) Test Test Test______________________________________Example 114 70/30 .largecircle.-.DELTA. .largecircle. SExample 115 " .largecircle. .largecircle. SExample 116 " .largecircle. .largecircle. SExample 117 " .largecircle. .largecircle. SExample 118 " .largecircle. .largecircle. SExample 119 " .largecircle. .largecircle. SExample 120 " .largecircle. .largecircle. SExample 121 " .largecircle. .largecircle. SExample 122 " .largecircle. .largecircle. SExample 123 50/50 .largecircle. .largecircle. SExample 124 40/60 .largecircle. .largecircle. S______________________________________
EXAMPLES 125 TO 126
In each monomer solution shown in Table 18 was dissolved 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide, and the solution was then placed in a glass tube and the latter was sealed up. Afterward, the glass tube was heated at 60.degree. C. for 24 hours, and successively it was further heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for each cured product, performance was evaluated by the same procedure as in Example 20, and the results are set forth in Table 18.
TABLE 18__________________________________________________________________________ Amount of Indirect Tensile Absorbed Water Monomer Solution Strength (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 125 D-MMA 250 0.55Example 126 D-MMA/1,6-hexane- 350 0.59 diol dimethacrylate 50/50Comp. Ex. 5 isobutyl methacrylate 188 0.98Comp. Ex. 6 ##STR18## 270 1.02__________________________________________________________________________
EXAMPLES 127 TO 137
Each polymer powder shown in Table 19 was mixed with a monomer solution at a weight ratio of 30/70 in which 0.5% by weight (with respect to the monomer solution) of benzoyl peroxide was dissolved, and the mixture was then placed in a glass tube. The latter was then sealed up and heated at 60.degree. C. for 24 hours and successively heated at 100.degree. C. for 24 hours in order to carry out polymerization, thereby obtaining a cured product. Next, for the thus cured product, performance was evaluated by the same procedure as in Example 125. The results are set forth in Table 19.
In this connection, properties of the polymer powders 5 used in these examples were the same as in Examples 27 to 37.
TABLE 19__________________________________________________________________________ Indirect Amount of Tensile Absorbed Composition of Powder-Solution Mixture Strength Water Polymer Powder Monomer Solution (kgf/cm.sup.2) (mg/cm.sup.2)__________________________________________________________________________Example 127 PMMA (*1) D-MMA 252 0.60Example 128 PEMA (*2) " 272 0.60Example 129 methyl methacrylate/ " 278 0.65 ethyl methacrylate copolymer (*3)Example 130 methyl methacrylate/ " 263 0.58 butyl methacrylate copolymer (*4)Example 131 polystyrene (*5) " 246 0.61Example 132 polybutyl methacrylate " 270 0.66 (PBMA) (*6)Example 133 methyl methacrylate/ " 252 0.63 styrene copolymer (*7)Example 134 ethyl methacrylate/ " 241 0.62 butyl methacrylate copolymer (*8)Example 135 ethyl methacrylate/ " 237 0.58 styrene copolymer (*9)Example 136 PMMA/PEMA = 50/50 " 254 0.61 (weight ratio)Example 137 PEMA/PBMA = 50/50 " 240 0.60 (weight ratio)__________________________________________________________________________
EXAMPLES 137 TO 140
Each PEMA powder having an average particle diameter shown in Table 20 (average molecular weight=230.times.10.sup.3) was mixed with a monomer mixture comprising D-MMA/1,6-hexanediol dimethacrylate=36/64 (weight ratio) at a ratio of 2:1, and for the resulting mixture, a dough stage time was then measured by the same procedure as in Example 38. The results are set forth in Table 20.
TABLE 20______________________________________ Average Diameter Period for of PEMA Powder Dough Stage (min) (.mu.m) End Start Pot Life______________________________________Example 138 84 62 12 50Example 139 52 42 17 25Example 140 25 30 15 15______________________________________

Number	Date	Country
1-207880	Aug 1989	JPX
2-1373	Jan 1990	JPX
2-1374	Jan 1990	JPX
2-136351	May 1990	JPX

Number	Name	Date	Kind
4674980	Ibsen et al.	Jun 1987
4782100	Iwamoto et al.	Nov 1988

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