Claims
- 1. A conductive polymer matrix comprising a molecule having binding specificity for a target molecule.
- 2. The conductive polymer matrix according to claim 1, wherein said molecule having binding specificity for a target molecule is an antibody, or an antigen binding fragment thereof.
- 3. The conductive polymer matrix according to claim 2, wherein said antibody is a monoclonal antibody.
- 4. The conductive polymer matrix according to claim 2, wherein said antibody binds to a CD34 determinant.
- 5. The conductive polymer matrix according to claim 1, wherein said molecule having binding specificity for a target molecule is selected from the group consisting of Fc receptor, Protein G, and avidin or avidin-related molecules.
- 6. A method for isolating a target molecule from a sample, said method comprising contacting said sample with a conductive polymer matrix, wherein said conductive polymer matrix comprises a molecule having binding specificity for a target molecule; binding of said target molecule to said molecule having binding specificity for said target molecule; and releasing said molecule having binding specificity for said target molecule from said conductive polymer matrix.
- 7. A method for isolating a target cell from a sample comprising a mixture of cells, said method comprising contacting said mixture of cells with a conductive polymer matrix, wherein said conductive polymer matrix comprises a molecule having binding specificity for a target molecule expressed on said target cell; binding of said target cell to said molecule having binding specificity for said target cell; and releasing said molecule having binding specificity for said target molecule from said conductive polymer matrix.
- 8. The method according to claim 7, wherein said method further comprises washing said polymer matrix to remove unbound material.
- 9. The method according to claim 7, wherein said conductive polymer matrix comprises an antibody.
- 10. The method according to claim 9, wherein said antibody is a monoclonal antibody.
- 11. The method according to claim 9, wherein said antibody binds to a CD34 determinant.
- 12. The method according to claim 7, wherein said target cell is a stem cell.
- 13. The method according to claim 7, wherein said conductive polymer matrix is formed using enzyme generated means.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a continuation of application U.S. Ser. No. 09/437,509, filed Nov. 10, 1999, which is a continuation of application U.S. Ser. No. 08/965,949, filed Nov. 7, 1997, now abandoned, which claims the benefit of provisional application U.S. Serial No. 60/030,725, filed Nov. 8, 1996.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60030725 |
Nov 1996 |
US |
Continuations (2)
|
Number |
Date |
Country |
Parent |
09437509 |
Nov 1999 |
US |
Child |
09981639 |
Oct 2001 |
US |
Parent |
08965949 |
Nov 1997 |
US |
Child |
09437509 |
Nov 1999 |
US |