The present disclosure generally relates to subterranean wellbore operations and equipment and, more specifically, to mechanisms for transferring hydraulic control from a primary safety valve to an insert safety valve.
Subsurface safety valves (SSSVs) are well known in the oil and gas industry and provide one of many failsafe mechanisms to prevent the uncontrolled release of wellbore fluids should a wellbore system experience a loss in containment. Typically, subsurface safety valves comprise a portion of a tubing string set in place during completion of a wellbore. Although a number of design variations are possible for subsurface safety valves, the vast majority are flapper-type valves that open and close in response to longitudinal movement of a flow tube. Since subsurface safety valves provide a failsafe mechanism, the default positioning of the flapper is usually closed in order to minimize the potential for inadvertent release of wellbore fluids. The flapper can be opened through various means of control from the earth's surface in order to provide a flow pathway for production to occur.
In many instances, the flow tube can be regulated from the earth's surface using a piston and rod assembly that may be hydraulically charged via a control line linked to a hydraulic manifold or control panel. The term “control line” will be used herein to refer to a hydraulic line configured to displace the flow tube of a subsurface safety valve downward upon pressurization, or otherwise to become further removed from the exit of a wellbore. When sufficient hydraulic pressure is conveyed to a subsurface safety valve via the control line, the piston and rod assembly forces the flow tube downward, which causes the flapper to move into its open position upon overcoming forces that tend to keep the flapper closed (e.g., biasing springs, downhole pressure, and the like). When the hydraulic pressure is removed from the control line, the flapper can return to its default, closed position. A self-closing mechanism, such as a torsion spring, can also be present to promote closure of the flapper should a loss of hydraulic pressure occur.
Some subsurface safety valves can also employ a second hydraulic line configured to counterbalance the effects of the control line and to provide an additional means of regulating the flow tube. The term “balance line” will be used herein to refer to a hydraulic line configured to displace the flow tube of a subsurface safety valve upward upon pressurization, or otherwise to become less removed from the exit of a wellbore. A balance line, when present, can operate in a similar manner to a control line and be controlled from the earth's surface.
Depending on operational considerations, a subsurface safety valve may be placed hundreds to thousands of feet downhole. During downhole placement of a subsurface safety valve, numerous opportunities exist for inadvertent damage to occur to the control line and/or the balance line, including line severance, thereby rendering the line(s) inoperative for regulating the subsurface safety valve. Line damage can also occur after a subsurface safety valve has been set in place and is in operational use. In addition to issues associated with the control line and/or the balance line, subsurface safety valves may become damaged due to corrosion or scaling and no longer function properly. In the event of hydraulic failure or related damage to a subsurface safety valve, very expensive and time-consuming workover operations may be needed to replace the non-functioning valve.
The following figures are included to illustrate certain aspects of the present disclosure and should not be viewed as exclusive embodiments. The subject matter disclosed is capable of considerable modifications, alterations, combinations, and equivalents in form and function, as will occur to one having ordinary skill in the art and the benefit of this disclosure.
The present disclosure generally relates to subterranean wellbore operations and equipment and, more specifically, to mechanisms for transferring hydraulic control from a primary safety valve to an insert safety valve.
One or more illustrative embodiments incorporating the features of the present disclosure are presented herein. Not all features of a physical implementation are necessarily described or shown in this application for the sake of clarity. It is to be understood that in the development of a physical implementation incorporating the embodiments of the present disclosure, numerous implementation-specific decisions may be made to achieve the developer's goals, such as compliance with system-related, business-related, government-related and other constraints, which may vary by implementation and from time to time. While a developer's efforts might be time-consuming, such efforts would be, nevertheless, a routine undertaking for one having ordinary skill in the art and the benefit of this disclosure.
In the description herein, directional terms such as “above”, “below”, “upper”, “lower”, and the like, are used for convenience in referring to the accompanying drawings. In general, “above”, “upper”, “upward” and similar terms refer to a direction toward the exit of a wellbore, often toward the earth's surface, and “below”, “lower”, “downward” and similar terms refer to a direction away from the exit of a wellbore, often away from the earth's surface.
Control line port 204 may be provided in housing 202 for connecting a hydraulic control line (not shown in
Piston assembly 210 is arranged within piston bore 208 and is configured to translate axially therein. Piston assembly 210 includes piston head 212 that mates with and otherwise biases up stop 214 defined within piston bore 208 when piston assembly 210 is forced upwards. Up stop 214 may be a radial shoulder defined by housing 202 within piston bore 208, which has a reduced diameter and an axial surface configured to engage a corresponding axial surface of piston head 212. Up stop 214 may generate a mechanical metal-to-metal seal between the two components to prevent the migration of fluids (e.g., hydraulic fluids, production fluids, and the like) therethrough. Other configurations of up stop 214 that are configured to arrest axial movement of piston assembly 210 are also possible.
Piston assembly 210 may also include piston rod 216 that extends longitudinally from piston assembly 210 through at least a portion of piston bore 208. At a distal end of piston rod 216, it may be coupled to actuator sleeve 218 for affecting motion of flow tube 220. Flow tube 220 is movably arranged within safety valve 16. More particularly, actuator sleeve 218 may engage biasing device 222 (e.g., a compression spring, a series of Belleville washers, or the like) arranged axially between actuator sleeve 218 and actuation flange 224 that forms part of the proximal end of flow tube 220. As actuator sleeve 218 acts upon biasing device 222 with axial force, actuation flange 224 and flow tube 220 correspondingly move axially in the direction of the applied force (i.e., downward with increasing hydraulic pressure). Down stop 236 may be arranged within the piston bore 208 in order to limit the range of axial motion of piston assembly 210. A metal-to-metal seal may be created between piston assembly 210 and down stop 236 such that the migration of fluids (e.g., hydraulic fluids, production fluids, and the like) therethrough is generally prevented.
Safety valve 16 further includes flapper valve 226 that is selectively movable between open and closed positions to either prevent or allow fluid flow through internal flowpath 228 defined through the interior of safety valve 16. Flapper valve 226 is shown in
Upon hydraulic pressurization and downward movement of piston rod 216, flow tube 220 is also displaced downward, eventually overcoming the force associated with torsion spring 230 and any associated downhole fluid pressures. At this point, flapper valve 226 moves from its closed position to an open position (shown in phantom in
Safety valve 16 may further contain lower chamber 232 within housing 202. In some embodiments, lower chamber 232 may form part of piston bore 208, such as being an elongate extension thereof. Power spring 234, such as a coil or compression spring, may be arranged within lower chamber 232 and correspondingly biases actuation flange 224 and actuation sleeve 218 upwardly, which, in turn, also biases piston assembly 210 in the same direction. That is, power spring 234 also resists the hydraulic pressure applied from the hydraulic control line and helps to prevent flapper valve 226 from being opened inadvertently. Accordingly, expansion of the power spring 234 causes piston assembly 210 to move upwardly within piston bore 208. It should be noted that in addition to power spring 234, other types of biasing devices, such as a compressed gas with appropriate sealing mechanisms, may be employed similarly.
As mentioned above, a hydraulic control line may provide hydraulic pressurization to safety valve 16 at control line port 204. However, more than one hydraulic line may be present in certain types of safety valves. For example, referring again to
As depicted in
As discussed above, failure of control line 20 or balance line 22 can render safety valve 16 at least partially inoperable. Failure of control line 20 can be particularly detrimental, since failure of this line leads to an inability to maintain safety valve 16 in an open position. Similarly, failure of safety valve 16 itself (e.g., due to corrosion or scaling) may prevent effective hydraulic control from taking place. To address the foregoing issues associated with an inoperable safety valve, hydraulic communication with safety valve 16 may be discontinued and hydraulic control may be transferred to an insert (secondary) safety valve that is located above safety valve 16 within tubing string 14, as discussed herein. The insert safety valve may be placed or inserted within tubing string 14 after the primary safety valve 16 has failed, specifically within the internal flow pathway (bore) of nipple 24. Accordingly, the term “insert safety valve” will be used herein to refer to a secondary safety valve that is used to replace or otherwise supplement an inoperative primary safety valve. The terms “insert safety valve” and “secondary safety valve” may be used interchangeably herein. These safety valves are not considered to be a redundant backup of the primary safety valve, but are instead placed in-line to supplant a failed primary safety valve by establishing a new hydraulic flow pathway. Effective replacement of a primary safety valve with an insert safety valve can allow production of wellbore fluids to continue without conducting an expensive and time-consuming workover operation to withdraw tubing string 14 for valve repair or replacement. Advantageously, the disclosure herein allows existing control lines and balance lines to be used for regulating the insert safety valve, rather than utilizing one or more new lines and increasing the number of penetrations through a tubing hanger.
With reference again being made to
According to various embodiments of the present disclosure, nipple 24 is configured such that hydraulic control of the insert safety valve can be established using control line 20 and balance line 22, once hydraulic control of safety valve 16 has been discontinued. Nipple 24 may be further configured to promote shutting off hydraulic communication with safety valve 16. Once hydraulic control of the insert safety valve in nipple 24 has been established, operation of this valve may take place in a manner substantially similar to that originally used for operating safety valve 16. That is, opening and closing of the insert safety valve may take place through appropriately pressurizing and de-pressurizing control line 20 and balance line 22. Advantageously, the embodiments of the present disclosure allow both control line 20 and balance line 22 to be used in operating the insert safety valve, thereby maintaining the desirable features afforded by the use of dual hydraulic lines in safety valve 16. However, single-line insert safety valves may also be used in a related manner.
In order for hydraulic control to be transferred to the insert safety valve in the foregoing manner, control line 20 and balance line 22 are placed in latent fluid communication with nipple 24 (latent fluid communication not shown in
In some embodiments, nipple 24 may be configured such that over-pressurization of at least one of control line 20 or balance line 22 results in a switch to the latent hydraulic lines in nipple 24. Over-pressurization may occur between a normal maximum operating pressure of these lines and their failure or bursting pressure. Specifically, control line 20 and balance line 22 may each contain a pressure-actuated device that is in fluid communication with these lines and initially blocks hydraulic access to the latent hydraulic lines within nipple 24. Upon over-pressurizing at least one of control line 20 and balance line 22, the pressure-actuated device activates and promotes switching to the latent hydraulic lines within nipple 24. That is, upon activation of the pressure-actuated device, hydraulic fluid gains access to at least a portion of the latent hydraulic lines within nipple 24.
In a first configuration, discontinuation of hydraulic communication with safety valve 16 may occur through sequential over-pressurization of control line 20 and balance line 22. Either control line 20 or balance line 22 may be over-pressurized first to affect switching of the other, depending upon which line is presently operative and capable of being pressurized. The over-pressurization of a first line may actuate a switching mechanism within nipple 24 that shuts off hydraulic communication between the opposing line and safety valve 16 and also activates a latent hydraulic line within nipple 24. By subsequently over-pressurizing the opposing line, closure of the first line may be affected and the remaining latent hydraulic lines may be activated. The activated latent hydraulic lines in nipple 24 can then be used to regulate the operation of an insert safety valve placed therein. Provided that at least one of control line 20 or balance line 22 remains intact below nipple 24 and can be over-pressurized, both lines may be switched to discontinue hydraulic communication with safety valve 16 and to activate the latent hydraulic lines within nipple 24. Further details in this regard are provided below.
In the interest of clarity, the disposition of nipple 24 and safety valve 16 within a tubing string are not depicted in
Once switching mechanism 28 has been actuated and the lower portion of control line 20 has been shut off, control line 20 may once again be hydraulically pressurized from the earth's surface. Hydraulic pressurization of control line 20 at this juncture may allow at least a portion of the latent hydraulic lines within nipple 24 to be accessed. Further, in order to redirect hydraulic control of balance line 22 into nipple 24 and to shut off a lower portion of balance line 22, control line 20 may be over-pressurized in a similar manner to that described above. Specifically, upon over-pressurization of control line 20, both pressure-actuated device 21 and switching mechanism 26 actuate to shut off the portion of balance line 22 below nipple 24, as depicted in
Upon re-directing both control line 20 and balance line 22 to access latent hydraulic lines within nipple 24, thereby shutting off safety valve 16 in the process, an insert safety valve may be lowered into the wellbore and positioned within the bore of nipple 24. Suitable techniques for positioning an insert safety valve within nipple 24, such as through wireline, braided line, or coiled tubing deployment, will be familiar to one having ordinary skill in the art. Before or after placing the insert safety valve, safety valve 16 may be mechanically locked in an open position such that it is permanently bypassed within the tubing string, thereby turning its fluid control function over to the insert safety valve. The insert safety valve may be operated in a substantially similar manner to that of safety valve 16 by pressurizing and depressurizing control line 20 and balance line 22 in a desired way. In alternative embodiments, a single-line insert safety valve may be used as an alternative to a dual-line safety valve, and such valves may be inserted after actuating only a single line (such as in the configuration of
Although
In still another alternative, the operations described above in reference to
Pressure-actuated devices 21 and 23 suitable for use in the embodiments described herein are not considered to be particularly limited and may include both pressure-relief valves that are actuatable multiple times or single-use devices, such as rupture discs. Pressure-relief valves that are actuatable multiple times may allow the crossover hydraulic pressurization to be discontinued once control line 20 and balance line 22 have been switched, which may be advantageous in certain instances. In either case, pressure-actuated devices 21 and 23 prevent pressurization of crossover hydraulic lines 25 and 27 from occurring until a threshold pressure value has been exceeded in control line 20 or balance line 22, as described above.
Switching mechanisms 26 and 28 may include any structure that is responsive to hydraulic pressure within crossover hydraulic lines 25 and 27, thereby allowing control line 20 and balance line 22 to be shut off below nipple 24. Suitable switching mechanisms 26 and 28 allow control line 20 and balance line 22 to remain open during normal operational conditions but become permanently closed once a threshold hydraulic pressure has been exceeded in crossover hydraulic lines 25 and 27, even after these lines are no longer over-pressurized. In addition, suitable switching mechanisms 26 and 28 may allow latent hydraulic lines within nipple 24 to become functional by connecting them to control line 20 and balance line 22, so that an insert safety valve within nipple 24 can be operated hydraulically by appropriately pressurizing and depressurizing control line 20 and balance line 22.
In some embodiments, switching mechanisms 26 and 28 may comprise a valve that permanently closes upon pressurization of crossover hydraulic lines 25 and 27. Valves suitable for this purpose will be familiar to one having ordinary skill in the art. In related embodiments, switching mechanisms 26 and 28 may comprise a piston within crossover hydraulic lines 25 and 27. In such embodiments, the piston may displace upon over-pressurization and initiate blocking fluid flow in control line 20 or balance line 22 below nipple 24, thereby allowing an upper portion of the line to be subsequently over-pressurized as described above. The piston may be locked in place upon being displaced in order to affect permanent closure of control line 20 and balance line 22.
In other embodiments, switching mechanisms 26 and 28 may comprise a normal valve that is propped open under standard operational conditions but closes in response to pressurization of crossover hydraulic lines 26 and 28. Normal valves that may be propped open under standard operational conditions include, for example, poppet-controlled valves, and ball valves. The mechanism by which the valve is propped open and subsequently closed will be dependent upon the type of valve, and such suitable mechanisms will be familiar to one having ordinary skill in the art.
In other illustrative embodiments, switching mechanism 26 or 28 may provide temporary closure within control line 20 or balance line 22 when the opposing line is being over-pressurized, and complete closure may occur upon over-pressurizing the now-closed line to promote closure within the originally over-pressurized line. For example, over-pressurization of a first line (e.g., balance line 22) may affect temporary closure of the opposing line (e.g., control line 20) and actuate a returnable blocking mechanism (e.g., a spring-loaded piston) within the first line. Upon over-pressurization of the temporarily closed opposing line (e.g., control line 22), it may become permanently closed by locking its switching mechanism into place. Temporary closure of the first line (e.g., balance line 22) may also occur upon over-pressurization of the opposing line. Subsequently, the first line may be permanently closed through over-pressurization of that line to lock its switching mechanism into place. An advantage of this approach is that an inadvertently over-pressurized line need not necessarily be permanently taken out of service. Suitable valves and like switching mechanisms for affecting temporary line closure will again be familiar to one having ordinary skill in the art.
In still other embodiments, switching mechanisms 26 and 28 may comprise one or more hydraulic spools that are configured to move in one or more switching chambers within nipple 24 in response to increased hydraulic pressure within crossover hydraulic lines 25 and 27. Such hydraulic spools may be configured to divert hydraulic fluid from control line 20 and balance line 22 to latent hydraulic lines within nipple 24, such that an insert safety valve placed within nipple 24 can be hydraulically controlled. As discussed further hereinbelow, hydraulic spools may also be actuated through over-pressurization originating from sources other than within control line 20 or balance line 22.
Under normal operational conditions (
As shown in
Although
In related embodiments, over-pressurization of either control line 20 or balance line 22 may be used to affect simultaneous switching of both lines to nipple 24 as well as activation of latent hydraulic lines 52 and 52′. Specifically, as shown in
Unlike the nipple configuration of
Although
In yet another related embodiment, nipple 24 may be configured such that over-pressurization of either control line 20 or balance line 22 affects simultaneous switching of both lines to within nipple 24, but without employing crossover hydraulic lines between control line 20 and balance line 22. Unlike the nipple configurations of
Unlike
As discussed in more detail above in reference to
In the configurations described above (see
As in other nipple configurations described herein, control line 20 and balance line 22 are configured to be transferrable from a primary safety valve (again, not shown in
Upon pressurizing pressurization chambers 46 and 46′ via the wellbore pressure differential originating within the lower bore section, hydraulic spools 48 and 48′ rise in response to the increased hydraulic pressure, as shown in
Pressurization chambers 46 and 46′ reside within housing 42 and pistons 49 and 49′ are disposed therein. Seals 51a-51d define a series of flow chambers within pressurization chamber 46, and seals 51a′-51d′ define a corresponding series of flow chambers within pressurization chamber 46′. In the un-switched configuration of
Upon placing insert safety valve 55 in bore 44, a pressure rise occurs within the lower section of bore 44, and switching conduits 91 and 91′ communicate the hydraulic pressure to pressurization chambers 46 and 46′, respectively. Upon sufficiently pressurizing pressurization chambers 46 and 46′, pistons 49 and 49′ rise, and the associated flow chambers also move correspondingly (
Although
Embodiments disclosed herein include:
A. Wellbore systems whose hydraulic regulation may be transferred from a primary safety valve to an insert safety valve. The wellbore systems comprise: a tubing string comprising a nipple and a primary safety valve, the primary safety valve being disposed in the tubing string below the nipple; and a control line and a balance line in hydraulic communication with the primary safety valve and in latent hydraulic communication with one or more switching mechanisms in the nipple; wherein the one or more switching mechanisms in the nipple are actuable to shut off the hydraulic communication of the control line and the balance line below the nipple and to redirect, via one or more latent hydraulic lines, the hydraulic communication of the control line and the balance line to an insert safety valve positioned in a bore of the nipple.
B. A method for transferring hydraulic regulation in a wellbore system by over-pressurizing one or more of a control line or a balance line. The methods comprise: placing a tubing string comprising a nipple and a primary safety valve into a wellbore, the primary safety valve being disposed in the tubing string below the nipple and the primary safety valve having a control line and a balance line in hydraulic communication therewith; wherein the control line and the balance line are also in latent hydraulic communication with one or more switching mechanisms in the nipple; and actuating the one or more switching mechanisms by over-pressurizing the control line, the balance line or both the control line and the balance line to shut off the hydraulic communication below the nipple and to redirect, via one or more latent hydraulic lines, the hydraulic communication of the control line and the balance line to an insert safety valve positioned in a bore of the nipple.
C. A method for transferring hydraulic regulation in a wellbore system by pressurizing a nipple bore. The methods comprise: placing a tubing string comprising a nipple and a primary safety valve into a wellbore, the primary safety valve being disposed in the tubing string below the nipple and the primary safety valve having a control line and a balance line in hydraulic communication therewith; wherein the control line and the balance line are also in latent hydraulic communication with one or more switching mechanisms in the nipple; and actuating the one or more switching mechanisms by pressurizing the bore of the nipple to shut off the hydraulic communication below the nipple and to redirect, via one or more latent hydraulic lines, the hydraulic communication of the control line and the balance line to an insert safety valve positioned in a bore of the nipple.
Each of embodiments A-C may have one or more of the following additional elements in any combination:
Element 1: wherein the one or more switching mechanisms actuate upon over-pressurization of the control line, the balance line, or both the control line and the balance line.
Element 2: wherein the wellbore system further comprises: first and second crossover hydraulic lines extending between the control line and the balance line, the first and second crossover hydraulic lines being in hydraulic communication with the one or more switching mechanisms in the nipple; a first pressure-actuated device interposed between the control line and the balance line in the first crossover hydraulic line; and a second pressure-actuated device interposed between the control line and the balance line in the second crossover hydraulic line.
Element 3: wherein the one or more switching mechanisms comprise one or more hydraulic spools that are actuable to establish hydraulic communication between an upper portion of the control line and a first latent hydraulic line and between an upper portion of the balance line and a second latent hydraulic line.
Element 4: wherein a first switching mechanism switches the control line and a second switching mechanism switches the balance line.
Element 5: wherein a single switching mechanism switches the control line and the balance line simultaneously.
Element 6: wherein the wellbore system further comprises: a first branch line extending from the control line, the first branch line being in latent hydraulic communication with the at least one switching mechanism and having a first pressure-actuated device interposed between the control line and the at least one switching mechanism; and a second branch line extending from the balance line, the second branch line being in latent hydraulic communication with the at least one switching mechanism and having a second pressure-actuated device interposed between the balance line and the at least one switching mechanism.
Element 7: wherein the at least one switching mechanism comprises at least one hydraulic spool.
Element 8: wherein a single switching mechanism switches the control line and the balance line simultaneously.
Element 9: wherein the one or more switching mechanisms actuate upon establishing a pressure differential between a lower section of a bore of the nipple and an upper section of the bore of the nipple.
Element 10: wherein the one or more switching mechanisms comprise one or more hydraulic spools or pistons, the wellbore system further comprising: one or more switching conduits that establish hydraulic communication between the one or more switching mechanisms and the bore of the nipple.
Element 11: wherein a first switching mechanism switches the control line and a second switching mechanism switches the balance line.
Element 12: wherein a single switching mechanism switches the control line and the balance line simultaneously.
Element 13: wherein over-pressurizing the control line or the balance line actuates a first switching mechanism within a one of the control line or the balance line that is not over-pressurized.
Element 14: wherein the method further comprises: after actuating the first switching mechanism, over-pressurizing a one of the control line or the balance line that was not originally over-pressurized to actuate a second switching mechanism for a one of the control line or the balance line that was originally over-pressurized.
Element 15: wherein a single switching mechanism switches the control line and the balance line simultaneously upon over-pressurization of either line.
Element 16: wherein the one or more switching mechanisms comprise one or more hydraulic spools that, upon actuation, establish hydraulic communication between an upper portion of the control line and a first latent hydraulic line and between an upper portion of the balance line and a second latent hydraulic line.
Element 17: wherein the one or more switching mechanisms comprise one or more hydraulic spools or pistons, and one or more switching conduits establish hydraulic communication between the one or more switching mechanisms and the bore of the nipple.
By way of non-limiting example, exemplary combinations applicable to A-C include:
The wellbore system of A in combination with elements 1 and 4.
The wellbore system of A in combination with elements 1 and 5.
The wellbore system of A in combination with elements 1-4.
The wellbore system of A in combination with elements 1-3 and 5.
The wellbore system of A in combination with elements 6 and 7.
The wellbore system of A in combination with elements 6-8.
The wellbore system of A in combination with elements 9 and 10.
The wellbore system of A in combination with elements 9-11.
The wellbore system of A in combination with elements 9, 10 and 12.
The method of B in combination with elements 13 and 14.
The method of B in combination with elements 13, 14 and 17.
The method of B in combination with elements 13, 15 and 17.
The method of B in combination with elements 13 and 16.
The method of B in combination with elements 15 and 16.
The method of C in combination with elements 4 and 17.
The method of C in combination with elements 5 and 17.
Unless otherwise indicated, all numbers expressing quantities of ingredients, properties such as molecular weight, reaction conditions, and so forth used in the present specification and associated claims are to be understood as being modified in all instances by the term “about.” Accordingly, unless indicated to the contrary, the numerical parameters set forth in the specification and attached claims are approximations that may vary depending upon the desired properties sought to be obtained by the embodiments of the present disclosure. At the very least, and not as an attempt to limit the application of the doctrine of equivalents to the scope of the claim, each numerical parameter should at least be construed in light of the number of reported significant digits and by applying ordinary rounding techniques.
Therefore, the present disclosure is well adapted to attain the ends and advantages mentioned as well as those that are inherent therein. The particular embodiments disclosed above are illustrative only, as the present disclosure may be modified and practiced in different but equivalent manners apparent to those skilled in the art having the benefit of the teachings herein. Furthermore, no limitations are intended to the details of construction or design herein shown, other than as described in the claims below. It is therefore evident that the particular illustrative embodiments disclosed above may be altered, combined, or modified and all such variations are considered within the scope and spirit of the present disclosure. The disclosure illustratively disclosed herein suitably may be practiced in the absence of any element that is not specifically disclosed herein and/or any optional element disclosed herein. While compositions and methods are described in terms of “comprising,” “containing,” or “including” various components or steps, the compositions and methods can also “consist essentially of” or “consist of” the various components and steps. All numbers and ranges disclosed above may vary by some amount. Whenever a numerical range with a lower limit and an upper limit is disclosed, any number and any included range falling within the range are specifically disclosed. In particular, every range of values (of the form, “from about a to about b,” or, equivalently, “from approximately a to b,” or, equivalently, “from approximately a-b”) disclosed herein is to be understood to set forth every number and range encompassed within the broader range of values. Also, the terms in the claims have their plain, ordinary meaning unless otherwise explicitly and clearly defined by the patentee. Moreover, the indefinite articles “a” or “an,” as used in the claims, are defined herein to mean one or more than one of the element that it introduces.
Filing Document | Filing Date | Country | Kind |
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PCT/US2015/050765 | 9/17/2015 | WO | 00 |
Publishing Document | Publishing Date | Country | Kind |
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WO2017/048265 | 3/23/2017 | WO | A |
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Number | Date | Country | |
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20180202261 A1 | Jul 2018 | US |