The present invention relates to a medical energy irradiating apparatus for irradiating a living tissue with energy to treat or diagnose the living tissue. More particularly, the present invention relates to a medical energy irradiating apparatus including a temperature sensor disposed in an insert portion to be inserted into a living body for accurately measuring the temperature of the living body, which it is being irradiated with an energy during treatment or diagnosis, without the need for thrusting into the living body.
There have been known in the art medical energy irradiating apparatus having an elongate insert portion to be inserted into a living body through a body cavity or a small incision. When the insert portion is inserted into the living body, the insert portion irradiates a living tissue including an affected region with an energy such as a laser beam, a microwave, a radio wave, an ultrasonic wave, or the like to thermally modify, necrose, coagulate, cauterize, or evaporate the tissue of the affected region or a surrounding tissue including the affected region.
The medical energy irradiating apparatus generally directly apply the energy to the surface layer of a living tissue or the affected region positioned closely thereto. The medical energy irradiating apparatus are also used to treat, with heat, an affected region positioned deeply in a living tissue, such as a prostatic hypertrophy, a prostatic cancer, or a prostatitis.
For example, International Publication No. WO93/04727 discloses a technique proposing a process of applying a laser beam to solidify or contract some tissue of a cancer or a prostate. According to this technique, a coolant is introduced into a balloon to prevent the surface of a urethra held in contact with the balloon from being heated, while only the cancer or the prostate located inside is being heated. However, since the laser beam is applied from a fixed laser beam irradiator, the laser beam needs to be applied at a low output level to prevent the surface of a urethra from being heated. Hence, the laser beam needs to be applied for a long period of time. International Publication No. WO93/04727 reveals a balloon catheter having a thermocouple disposed in the balloon to be located in an intermediate position in a prostatic urethra for monitoring the temperature of a urethral tissue. The thermocouple is disposed within the balloon and held out of direct contact with the urethra, and the coolant is circulated through the balloon. Therefore, the temperature measured by the thermocouple does not appear to be accurately representative of the temperature of the prostatic urethra. U.S. Pat. No. 5,964,791 discloses a process of thrusting into a prostate with a temperature sensor to accurately measure the temperature of the urethra (direct measuring process).
U.S. Pat. No. 6,579,286 discloses, as an example of heat treatment device, a laser beam irradiating apparatus for guiding a laser beam into a urethra to treat a prostatic hypertrophy. The laser beam irradiating apparatus has a laser beam irradiation portion that is continuously movable to change the direction of the applied laser beam at all times. However, since the laser beam irradiating apparatus is arranged to concentrate the laser beam on a target region, the target region is heated to a high temperature while holding a surrounding tissue around the target region at a lower temperature. Even if the target region is positioned deeply in the living tissue, therefore, any damage to the living tissue that is located between the laser beam irradiator and the target region is minimized.
A therapeutic procedure for treating a prostatic hypertrophy with the laser beam irradiating apparatus will be described below. First, the doctor inserts the insert portion of the laser beam irradiating apparatus into the urethra of the patient. The insert houses therein a laser beam irradiator having a reflecting surface for reflecting a laser beam which is generated by a laser beam generator, guided by an optical fiber, and emitted from the tip end of the optical fiber. The insert portion also houses therein an endoscope, and inlet outlet pipes for a coolant for cooling the laser beam irradiator. Then, the doctor positions the laser beam irradiator while observing the urethra with the endoscope in the insert through an observation window disposed in the insert, and then applies the laser beam to a target region in the patient.
The heat treatment device referred to above needs to measure the temperature of a treated region in order to monitor the treatment in progress. The temperature of the treated region (the target region to be irradiated with the laser beam) positioned deeply in the living body can be measured by a process of thrusting into the living tissue with a temperature sensor to directly measure the temperature of the deep region (direct measuring process) or a process of bringing a temperature sensor into contact with the surface layer of the living body near the treated region to accurately measure the temperature of the surface layer of the living body and estimating the temperature of the deep region based on the measured temperature.
Though the direct measuring process is able to accurately measure the temperature of the treated region, it is disadvantageous in that it invites side effects such as hemorrhage and infectious disease because the living body is injured by being pierced with the temperature sensor, resulting in an increased number of days that the patient needs to stay in the hospital. For this reason, there has been a demand for a technique to accurately measure the temperature of the surface of the living body while it is being treated by an energy irradiation, thereby increasing the accuracy to estimate the temperature of a deep living tissue.
Problems that arise regarding the accurate measurement of the temperature of the surface of the living body will be described below. Conventional Temperature sensors have a temperature measuring element such as a thermistor and two leads connected thereto, which are placed in a tangle-free manner in a protective tube. However, the protective tube makes the insert portion to be inserted into the living body thick, posing an increased burden on the patient. The leads that are employed tend to cause the thermistor to be installed in different positions, making it impossible to measure accurate temperatures.
It may be proposed to place the temperature measuring element and the leads within the insert portion. If the temperature measuring element is placed in the insert portion of an energy treatment device where a coolant is circulated in the insert portion for cooling an energy emission unit and the living body contacted by the insert portion, then the coolant affects the temperature measuring element. Consequently, there has been desired a temperature sensor less susceptible to the coolant and is yet capable of accurately measuring the surface temperature of a living body.
One solution would be to attach the temperature measuring element and the leads to the outer surface of the insert. However, this approach needs to meet the following requirements:
1. The temperature measuring element will not be affected by the coolant.
2. The temperature measuring element will be installed easily and accurately in a desired position.
3. When the temperature measuring element and the leads are attached, the leads will not be damaged and will keep electrically connected to the temperature measuring element.
4. The insert portion will not have protrusions on its surface, which would otherwise be liable to damage the living body when the insert portion is inserted into the living body.
5. The temperature measuring element will not be directly affected by the energy that is applied to the living body.
It is therefore an object of the present invention to provide a medical energy irradiating apparatus of a structure that is simple and inexpensive to manufacture and capable of accurately measuring the temperature of a living tissue when the doctor treats a prostatic hypertrophy or a prostatic cancer with heat, using the medical energy irradiating apparatus.
To achieve the above object, a medical energy irradiating apparatus includes an insert portion for being inserted into a living body, a temperature sensor disposed on the insert portion, and an energy irradiating for applying an energy to a living tissue of the living body. The temperature sensor includes a single flexible thin-film substrate, at least first and second conductors disposed on the thin-film substrate, and a temperature measuring unit. The temperature measuring unit is disposed on the insert portion.
Preferably, the temperature measuring unit includes substantially plate-like first and second electrodes disposed on the thin-film substrate and electrically coupled respectively to the first and second conductors, and a substantially plate-like temperature measuring element. The first and second electrodes are electrically coupled to the temperature measuring element.
Preferably, the temperature measuring element has a first surface disposed on the first electrode, the first electrode being fixed and electrically coupled to the temperature measuring element, and wherein the temperature measuring element has a second surface opposite to the first surface, the second electrode being disposed on the second surface, the second electrode being electrically coupled to the temperature measuring element.
Preferably, the single flexible thin-film substrate is curved to dispose the second electrode on a second surface opposite to a first surface of the temperature measuring element.
Preferably, the thin-film substrate is disposed along a longitudinal direction on an outer surface of the insert portion.
Preferably, the medical energy irradiating apparatus further includes a covering tube covering a portion of an outer surface of the insert portion and thermally shrunk over the insert portion and the temperature sensor to press the temperature measuring element and the second electrode against each other.
Preferably, the temperature sensor further includes a thin metal film shielding the temperature measuring element against light.
Preferably, the thin metal film is disposed on the thin-film substrate, and the thin-film substrate with the metal film disposed thereon is folded to cover the temperature measuring element.
Preferably, the medical energy irradiating apparatus further includes an energy irradiating window for applying an energy therethrough to a living tissue of the living body. The temperature measuring unit being disposed on said energy irradiating window.
Preferably, the insert portion includes a hollow cylinder, the hollow cylinder having an opening defined in a side wall thereof and serving as the energy irradiating window.
Preferably, the medical energy irradiating apparatus further includes an optically transparent glass applied to the hollow cylinder in covering relation to the opening.
Preferably, the medical energy irradiating apparatus further includes an optically transparent synthetic resin film applied to the hollow cylinder in covering relation to the opening.
Preferably, the optically transparent synthetic resin film prepares scale, which is for operator to measure tissue surface.
Preferably, the medical energy irradiating apparatus further includes at least an outer tube covering the opening portion.
Preferably, the thin-film substrate has depth markers for the user to read a length by which the insert portion is inserted into the living body.
Preferably, the temperature sensor further includes maximum surface temperature estimating means for estimating a maximum temperature of a surface of the living tissue, which is irradiated with the energy, based on a temperature measured by the temperature sensor.
Preferably, the temperature sensor further includes deep region temperature estimating means for estimating a deep region temperature in the living tissue, which is irradiated with the energy, based on a temperature measured by the temperature sensor.
Preferably, the temperature sensor further includes control means for controlling the energy applied to the living tissue based on a temperature measured by the temperature sensor.
Preferably, the energy includes laser.
Preferably, the medical energy irradiating apparatus further includes irradiating means disposed in the insert and having a reflecting surface for reflecting the laser beam through the energy irradiating window to the living tissue, moving means for reciprocating moving the irradiating means in a longitudinal direction of the insert, angle changing means for changing an angle through which the energy is applied to the living tissue by the irradiating means, and decision means for determining whether the irradiating means is correctly controlled to move reciprocating by the moving means based on a temperature measured by the temperature sensor.
According the present invention, there is also provided a medical energy irradiating apparatus including an insert for being inserted into a living body, an energy irradiating window defined in a side wall of the insert for applying a generated energy therethrough to a living tissue of the living body, and a plurality of temperature sensors disposed in respective different positions on an outer surface of the insert. Each of the temperature sensors includes a single flexible thin-film substrate, at least first and second conductors disposed on the thin-film substrate, and a temperature measuring unit.
The medical energy irradiating apparatus according to the present invention is capable of accurately measuring the temperature of a living tissue as it is treated with heat, though the medical energy irradiating apparatus is simple in structure and inexpensive to manufacture. Therefore, the doctor who operates the medical energy irradiating apparatus can correctly monitor the temperature of the living tissue as it is treated with heat to cure a prostatic hypertrophy, for example, and hence can treat the living tissue with greater safety.
These and other objects of the invention will be seen by reference to the description, taken in connection with the accompanying drawing, in which:
The present invention will be described below as being applied to a medical energy irradiating apparatus for treating, with heat, a prostatic hypertrophy. However, the principles of the present invention are not limited to such a medical energy irradiating apparatus for treating, with heat, a prostatic hypertrophy. A laser beam will be described as an example of energy used for treating, with heat, a prostatic hypertrophy. However, the energy is not limited to a laser beam, but an electromagnetic wave such as a microwave, a radio wave, or the like, or an elastic wave such as an ultrasonic wave, a sound wave, or the like may be used as the energy.
The laser beam that can be used may include a divergent beam, a parallel beam, or a convergent beam. An optical system for converting a laser beam into a convergent beam may be disposed in the path of the laser beam. Though the laser beam is not limited to any particular laser beams insofar as they can reach a deep region in a living body, the laser beam should preferably have a wavelength ranging from 500 to 2600 nm, more preferably from 750 to 1300 nm or from 1600 to 1800 nm. The laser beam may be generated by a gas laser such as an He—Ne laser or the like, a solid-state laser such as an Nd-YAG laser or the like, or a semiconductor laser such as a GaAlAs laser or the like.
[Medical Energy Irradiating Apparatus (
As shown in
The insert portion 103 houses therein a laser beam irradiation portion 20 that is reciprocating movable in the longitudinal direction of the insert portion 103. A laser beam is guided by an optical fiber 12 extending through the applicator 110 and emitted from the distal end of the optical fiber 12. The laser beam emitted from the optical fiber 12 is reflected by the laser beam irradiation portion 20 and applied through a laser beam irradiating window defined in a side wall of the insert portion 103 to a target region T-1 to be irradiated in a living tissue T.
The laser beam irradiation portion 20 is coupled through a reciprocating movable member 23 (see
The drive unit 150 has a cam mechanism (not shown) for converting rotary motion of a motor 188 into reciprocating motion. Therefore, when the motor 188 is energized, its rotary motion is converted by the cam mechanism into reciprocating motion that is transmitted to the reciprocating movable member 23, which moves the laser beam irradiation portion 20 in the longitudinal direction of the insert portion 103.
The applicator 110 has a plurality of lumens (not shown) defined longitudinally therein and communicating with the insert portion 103 for circulating a coolant. The lumens are connected respectively to a coolant supply tube 185 and a coolant return tube 186 which extend from a coolant circulator 104. The coolant is supplied through the coolant supply tube 185 to the insert portion 103 to cool the laser beam irradiation portion 20 for thereby preventing the laser beam irradiation portion 20 from being overheated, and also to cool the surface of the body cavity U, which is held in contact with the insert portion 103 through the wall of the insert portion 103, for thereby preventing a correct body tissue, which is heated by the applied laser beam, from being damaged.
The coolant circulator 104 supplies the coolant at a preset rate through the applicator 110 to the insert portion 103 based on a control signal from a controller 106. A coolant temperature regulator 105 that is coupled to the coolant circulator 104 heats or cools the coolant in the coolant circulator 104 to regulate the temperature of the coolant based on a control signal from a controller 106. The motor 188 is energized to rotate a preset rotational speed based on a control signal from a controller 106.
The controller 106 has a console 108 serving as an input unit, a display 107 for displaying input information and apparatus information, a control unit (not shown) for controlling various parts of the controller 106, a memory (not shown) for storing various items of information, and an input/output unit (not shown) for inputting and outputting various items of information.
The coolant is supplied from the coolant circulator 104 through the coolant supply tube 185 to the insert portion 103, the motor 188 is rotated, and a laser beam generator 102 is operated to treat, with heat, a prostatic target region T-1 (target point) to be irradiated with a laser beam.
A laser beam generated by the laser beam generator 102 is transmitted through the optical fiber 12 to the laser beam irradiation portion 20 in the insert portion 103, which reflects the laser beam through the laser beam irradiating window to the target region T-1. At this time, the laser beam irradiation portion 20 is reciprocating moved axially in the insert portion 103 in periodic cycles at a frequency ranging from 2 to 10 Hz, preferably 3 to 9 Hz, periodically changing the angle of irradiation. Since all the paths along which the reflected laser beam travels cross the target region T-1 at all times, the target region T-1 is continuously irradiated with the laser beam and generates a large amount of heat. Therefore, the target region T-1 is kept at a high temperature and can effectively be treated with heat. On the other hand, the surface layer of-the body cavity U is intermittently irradiated with the laser beam, generating a small amount of heat, and is cooled by the coolant supplied to the insert portion 103. Consequently, the surface layer of the body cavity U is protected from and hence is not susceptible to the heat of the laser beam.
[Insert Portion (
The insert portion 103 will be described in greater detail below.
The insert portion 103 includes an elongate hollow cylinder 14 made of a hard pipe material such as stainless steel or the like, with an opening 15 defined in a side wall of the hollow cylinder 14. A graduated window seal is applied over the opening protion 15, providing a laser beam irradiating window 17. A temperature sensor 11 is mounted on the hollow cylinder 14. As shown in
The insert portion 103 houses therein a pair of walls 40, 41 spaced laterally from each other, defining an inner space therebetween in the insert portion 103. The insert portion 103 also houses therein the laser beam irradiation portion 20 with the reflecting surface 21, the reciprocating movable member 23, a monorail pipe 25, nonparallel grooves 42, an endoscope 6, and coolant lumens. The reciprocating movable member 23 supports the laser beam irradiation portion 20. The monorail pipe 25 has the reciprocating movable member 23, which is reciprocating movable in the longitudinal direction of the insert portion 103. The nonparallel grooves 42 are defined in the respective walls 40, 41 for changing the angle of the laser beam irradiation portion 20 so that the laser beam reflected by the laser beam irradiation portion 20 is applied to the target region at all times. The endoscope 6 observes the living tissue. The laser beam irradiation portion 20 is rotatably supported on a pair of pivots 27 fixed to respective left and right sides of the reciprocating movable member 23 that is fixed to the distal end of the optical fiber 12. The laser beam irradiation portion 20 has a pair of lugs 26 mounted on respective left and right sides thereof and slidably fitted respectively in the nonparallel grooves 42 defined in the walls 40, 41. The nonparallel grooves 42 extend out of parallel with the longitudinal axis of the insert portion 103.
Major components of the insert portion 103 will be described below.
[Laser Beam Irradiating Window (
The graduated glass strip 19A or 19B is produced by pressing a thin glass sheet into an arcuately curved glass strip with heat, and making scale (graduation) 18A on the surface of the arcuately curved glass strip. The scale 18A is used to determine a position to be irradiated with a laser beam. The scale 18A is formed by printing or the like, at a position not obstructing the path of the laser beam and in a color that is not liable to absorb the laser beam.
The glass with scale (graduation) strip 19A or 19B is fixed in position over the opening 15. An adhesive is applied to an end of the glass with scale strip 19A, and the glass with scale strip 19A is fitted into the opening 15 from above and bonded to the hollow cylinder 14, as indicated at (1) in (a) of
The temperature sensor 11 is fixed in the position shown in
The opening 15 is sealed with the window seal with scale 18. The window seal with scale 18, which is coated with an adhesive on its reverse side, is applied and bonded from above to the hollow cylinder 14 over the opening 15, as shown in
[Structure of the Temperature Sensor (FIGS. 7A through 7C)]
As shown in
[First Feature of the Temperature Sensor (thickness)]
According to a first feature of the temperature sensor 11, the temperature measuring element 11-1 includes a thin thermistor to make the temperature sensor 11 as thin as possible. The temperature measuring element 11-1 is in the form of a rectangular parallelepiped and has upper and lower surfaces serving as electrically coupling surfaces. The temperature measuring element 11-1 can have its temperature accurately measured by measuring the electric resistance between the upper and lower surfaces thereof. The upper and lower surfaces of the temperature measuring element 11-1 are held in contact with the electrodes 11-4B, 11-4A, which are in the form of flat plates. For example, the components of the temperature sensor 11 have thicknesses as follows: The thickness of the thin-film substrate 11-3 is in the range from 10 to 20 μm. The thickness of the conductors 11-6 is in the range from 10 to 20 μm. The thickness of the thin-film substrate 11-4 is in the range from 10 to 20 μm. The thickness of the temperature measuring element 11-1 is about 150 μm. The thickness of the laser beam shield plates 11-5A, 11-5B is in the range from 5 to 10 μm. Therefore, the thickness of the temperature sensor 11, i.e., the thickness of the temperature measuring unit, is about 200 μm.
In
[Second Feature of the Temperature Sensor (pressing electrode: FIGS. 8A through 8D)]
A pressing electrode according to a second feature of the temperature sensor 11 will be described below. Prior to describing the pressing electrode, a process of assembling the temperature measuring unit of the temperature sensor 11 will first be described below with reference to
The temperature sensor 11 is assembled as shown in
As can be understood from the above process of manufacturing the temperature sensor 11, the second feature of the temperature sensor 11 is that the electrode 11-4B and the temperature measuring element 11-1 are electrically coupled to each other, but not bonded to each other by a conductive adhesive. Therefore, when the temperature sensor 11 is bonded to the hollow cylinder 14, the temperature sensor 11 can be adjusted in length and any damage to the temperature sensor 11 can be reduced.
Specifically, when the temperature sensor 11 with the temperature measuring unit, which is of a flat shape as shown in
According to the present invention, inasmuch as the temperature measuring element 11-1 and the electrode 11-4B are not bonded to each other by a conductive adhesive, the electrode 11-4B held in contact with the temperature measuring element 11-1 can be moved relatively thereto under developed tensile stresses. Consequently, the temperature measuring unit can be arcuately curved along the arcuate surface of the hollow cylinder 14. Since the developed tensile stresses are reduced, the temperature sensor 11 is prevented from being broken by its length adjusting function even when the temperature sensor 11 is bonded to the arcuate outer surface of the hollow cylinder 14.
As described above, one of the two electrodes held in contact with the temperature sensor 11 is brought into contact with the temperature sensor 11 by folding over the thin-film substrate 11-3. Thus, the temperature sensor 11 can easily and accurately be installed in position on the arcuately curved surface of the hollow cylinder 14.
However, because the electrode 11-4B and the temperature measuring element 11-1 of the temperature sensor 11 on the outer surface of the hollow cylinder 14 are not bonded to each other, their contacting surfaces may possibly be spaced from each other when the temperature sensor 11 is in use. If the contacting surfaces of the electrode 11-4B and the temperature measuring element 11-1 are spaced from each other, then the temperature sensor 11 will not function properly. To avoid this drawback, after the temperature sensor 11 is bonded to the outer surface of the hollow cylinder 14, the outer tube 16 is placed over the hollow cylinder 14 and then thermally shrunk to press the temperature sensor 11 in position, as described above with reference to
[Reflecting Surface (
The reflecting surface 21 of the laser beam irradiation portion 20 disposed in the insert portion 103 will be described below. The reflecting surface 21 constitutes part of the laser beam irradiation portion 20, and has a smooth surface for reflecting the laser beam emitted from the distal end of the optical fiber 12 through the laser beam irradiating window 17 to the target region T-1.
[Monorail Pipe (
As shown in
The cleaning liquid may be a liquid such as sterilized water or sterilized physiological saline. The cleaning liquid is introduced under pressure from the cleaning unit (not shown) into the monorail pipe 25 to remove dirty deposits from the front window 32, and supplied through a cleaning liquid passage in the insert portion 103 to the front window 32 to remove dirty deposits on the front window 32.
The cleaning liquid may be replaced with a cleaning gas such as compressed air, a nitrogen gas, an oxygen gas, a carbon dioxide gas, or the like.
[Reciprocating Movable Member (
The reciprocating movable member 23 serves to change the direction of the applied laser beam depending on the irradiating position thereof when the reciprocating movable member 23 moves on the monorail pipe 25 in the directions indicated by the arrows, i.e., in the longitudinal directions of the applicator 110, e.g., from the position (a) to the position (b) to the position (c) to the position (b) to the position (a). Therefore, the direction of the applied laser beam and the irradiating position thereof can continuously be changed to control the laser beam to irradiate the target position at all times.
The reciprocating movable member 23 supports the laser beam irradiation portion 20 for reciprocating movement therewith. The reciprocating movable member 23 is positioned on one end of the laser beam irradiation portion 20, and the lugs 26 are positioned on the opposite end of the laser beam irradiation portion 20. The laser beam irradiation portion 20 is mounted on the reciprocating movable member 23 by the pivots 27 for free angular movement with respect to the reciprocating movable member 23 for thereby allowing the angle of the reflecting surface 21 to be changed with respect to the reciprocating movable member 23. The lugs 26 are fitted in the respective nonparallel grooves 42 that are defined in the inner surfaces of the walls 40, 41 disposed in the insert portion 103.
The reciprocating movable member 23 is coupled to the drive unit 150 (see
[Direction of the Applied Laser Beam (
As shown in
The laser beam reflected by the laser beam irradiation portion 20 is applied to the target region T-1 (target point) of the prostate T at all times when the reciprocating movable member 23 is in the positions P1 through P3. Therefore, the laser beam continuously irradiates the target region T-1, and intermittently irradiates other tissue regions such as the surface layer of the body cavity U. The target region T-1 that is continuously irradiated with the laser beam generates a large amount of heat and reaches a desired high temperature, whereas the surface layer of the body cavity U, which is intermittently irradiated with the laser beam, generates a small amount of heat and is not heated to a high temperature. Consequently, only the target region T-1 and its surrounding regions are selectively heated by the laser beam for treatment with heat.
The laser beam irradiation portion 20 for reflecting the laser beam is reciprocating moved on and along the monorail pipe 25 in periodic cycles at a frequency ranging from 2 to 10 Hz, preferably 3 to 9 Hz, in the longitudinal direction of the insert portion 103 while changing its angle.
[Nonparallel Grooves (
Structural details of the nonparallel grooves 42 will be described below with reference to
As shown in
Coolant outlet lumens 51, 52 for returning the coolant from the distal end of the insert portion 103 to the coolant circulator 104 are disposed between the circumferential wall of the hollow cylinder 14 and the walls 40, 41.
The position of the nonparallel grooves 42 at the position in
Likewise, the position of the nonparallel grooves 42 at the position in
Consequently, the laser beam reflected by the laser beam irradiation portion 20 is concentrated on the target region T-1 at all times based on the different vertical positions of the nonparallel grooves 42.
[Temperature Control System (
A temperature control system of the medical energy irradiating apparatus will be described below.
Operation of the control circuit will be described below. The console 207 includes a keyboard or the like. The user enters from the console 207 a signal for starting various processes for displaying a maximum surface temperature, displaying a deep region temperature, determining an incorrect irradiation timing, and controlling a laser beam output level. When the CPU 201 receives a command for executing the various processes, the CPU 201 operates according to the control program stored in the ROM 202 to receive measured values of the surface temperature from the temperature sensor 11 in the insert portion 103, store the measured values in the RAM 204, and control the laser beam generator 206 and the display 203 based on the measured values for displaying a maximum surface temperature, displaying a deep region temperature, determining an incorrect irradiation timing, and controlling a laser beam output level.
[Process of Estimating Maximum Cavity Wall Temperature (
A process of estimating a maximum cavity wall temperature upon laser beam irradiation from measured values of the surface temperature, which are produced by the temperature sensor 11 in the insert portion 103 when the doctor treats an affected region with the medical energy irradiating apparatus 10, will be described below.
First, measuring conditions will be described below. The temperature sensor 11 is disposed at a circumferential end of the laser beam irradiating window 17 shown in
Tmax=Tcool+α(Tu−Tcool) (1)
the maximum cavity wall temperature Tmax can be estimated from the surface temperature Tu upon laser beam irradiation according to the equation (1).
Based on the above experimental results, a control program for calculating the maximum cavity wall temperature Tmax from the surface temperature Tu upon laser beam irradiation is produced and stored in the ROM 202.
In step S301, Tcool and a are set. In step S302, the surface temperature Tu is measured. In step S303, the maximum cavity wall temperature Tmax is calculated according to the equation (1). In step S304, the measured surface temperature Tu and the calculated maximum cavity wall temperature Tmax are displayed on the display. If a next measuring cycle is to be performed in step S305, then control goes back to step S302, and the above process is repeated. If the present measuring cycle is to be finished in step S305, then control goes to step S306, putting the process to an end.
[Process of Estimating Deep Region Temperature (
A process of estimating a deep region temperature in a living body upon laser beam irradiation from measured values of the surface temperature, which are produced by the temperature sensor 11 in the insert portion 103 when the doctor treats an affected region with the medical energy irradiating apparatus 10, will be described below.
First, measuring conditions will be described below. The temperature sensor 11 is disposed at a circumferential end of the laser beam irradiating window 17 shown in
A process that is the same as the process described above with reference to
Tp=Tu0+β(Tu−Tu0) (2)
the deep region temperature Tp can be estimated from the surface temperature Tu upon laser beam irradiation according to the equation (2).
Based on the above experimental results, a control program for calculating the deep region temperature Tp from the surface temperature Tu upon laser beam irradiation is produced and stored in the ROM 202. FIG. 16 shows a process carried out by the CPU 201 according to the control program. The process is started when the doctor enters an execution command and initial values for executing the control program from the console when the doctor treats an affected region with the medical energy irradiating apparatus.
In step S401, Tu0 and β are set. In step S402, the surface temperature Tu is measured. In step S403, the deep region temperature Tp is calculated according to the equation (2). In step S404, the measured surface temperature Tu and the calculated deep region temperature Tp are displayed on the display. If a next measuring cycle is to be performed in step S405, then control goes back to step S402, and the above process is repeated. If the present measuring cycle is to be finished in step S405, then control goes to step S406, putting the process to an end.
[Monitoring of Reciprocating Motion Timing (
A process of monitoring irradiation timing upon laser beam irradiation from measured values of the surface temperature, which are produced by the temperature sensor 11 in the insert portion 103 when the doctor treats an affected region with the medical energy irradiating apparatus 10, will be described below.
First, measuring conditions will be described below. The temperature sensor 11 is disposed at a circumferential end of the laser beam irradiating window 17 shown in
[Detection of a Laser Beam Output Level]
The output level of a laser beam emitted from the laser beam generator can be measured from the range of temperature changes shown in
Based on the above experimental results, a control program for determining whether the irradiation timing is correct or not from the surface temperature Tu upon laser beam irradiation is produced and stored in the ROM 202.
In step S501, the surface temperature Tu is measured for a certain period of time. In step S502, the measured surface temperature Tu is displayed. In step S503, the number of periodic temperature changes is measured in the above period of time from the measured values of the surface temperature Tu, and it is checked whether or not the measured number of periodic temperature changes agrees with a preset number of periodic temperature changes. If the measured number of periodic temperature changes agrees with the preset number of periodic temperature changes, then control goes to step S506 in which correct reciprocating motion timing is displayed. Then, control goes to step S507 to put the process to an end. If the measured number of periodic temperature changes does not agree with the preset number of periodic temperature changes, then control goes to step S505 in which incorrect reciprocating motion timing is displayed. Then, control goes to step S507 to put the process to an end.
[Control of a Laser Beam Output Level (
A process of controlling a laser beam output level upon laser beam irradiation based on measured values of the surface temperature, which are produced by the temperature sensor 11 in the insert portion 103 when the doctor treats an affected region with the medical energy irradiating apparatus 10, will be described below.
First, measuring conditions will be described below. The temperature sensor 11 is disposed at a circumferential end of the laser beam irradiating window 17 shown in
In step S601, a temperature rise pattern Tutarget(t) of the surface temperature upon laser beam irradiation is determined. Specifically, the doctor selects a desired one of a plurality of preset temperature rise patterns, and the CPU 201 determines the temperature rise pattern based on a selection signal entered by the doctor. In step S602, an initial laser beam output level is set. In step S603, the target region is irradiated with a laser beam having the initial laser beam output level. In step S604, the surface temperature Tu(t) upon laser beam irradiation is measured. In step S605, the measured surface temperature Tu(t) is compared with the temperature rise pattern Tutarget(t). If Tutarget(t)<Tu(t) in step S605, then control goes to step S606 in which the laser beam output level P is changed to P−ΔP, after which control goes to step S609. If Tutarget(t)=Tu(t) in step S605, then control goes to step S607 in which the laser beam output level P is not changed, but maintained, after which control goes to step S609. If Tutarget(t)>Tu(t) in step S605, then control goes to step S608 in which the laser beam output level P is changed to P+ΔP, after which control goes to step S609. If a next output level controlling cycle is to be performed in step S609, then control goes back to step S603, and the above process is repeated. If the present output level controlling cycle is to be finished in step S609, then control goes to step S610, putting the process to an end.
[Another Embodiment (
In the above embodiment, the single temperature sensor 11 is disposed in the insert portion 103 as shown in
The medical energy irradiating apparatus according to the present invention should preferably be used to treat a prostate with heat to cure a prostatic disease such as a prostatic hypertrophy, a prostatic cancer, or the like while reducing damage to a correct living tissue, such as the urethra, the rectum, or the like, that is positioned closely to the prostate.
As described above, the temperature measuring unit of the temperature sensor according to the present invention has the electrodes disposed on the upper and lower surfaces of the temperature measuring element, the thin-film substrates disposed on the upper and lower surfaces of the electrodes, and the laser beam shield plates disposed on the upper and lower surfaces of the thin-film substrates. The electrode 11-4A is bonded to the temperature measuring element by the conductive adhesive, and the electrode 11-4B is not bonded to the temperature measuring element by the conductive adhesive. When the temperature sensor is bonded to the hollow cylinder of the insert, the temperature measuring unit is curved along the surface of the hollow cylinder, tending to develop tensile stresses in the electrode 11-4B. At this time, the electrode 11-4B, which is not bonded to the temperature measuring element, is positionally displaced depending on the developed tensile stresses, allowing the temperature sensor to be adjusted in length. Consequently, the temperature sensor is prevented from being broken or damaged. Therefore, the medical energy irradiating apparatus according to the present invention is capable of accurately measuring the temperature of a living tissue as it is treated with heat, though the medical energy irradiating apparatus is simple in structure and inexpensive to manufacture. Therefore, the doctor who operates the medical energy irradiating apparatus can correctly monitor the temperature of the living tissue as it is treated with heat to cure a prostatic hypertrophy, for example, and hence can treat the living tissue with greater safety.
While preferred embodiments of the invention have been described using specific terms, such description is for illustrative purposes only, and it is to be understood that changes and variations may be made without departing from the spirit of scope of the following claims.
Number | Date | Country | Kind |
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2004-106089 | Mar 2004 | JP | national |