The present application claims priority to Chinese patent application No. 202211738761.8, filed on Dec. 30, 2022, the entire contents of which are incorporated herein by reference.
The present disclosure relates to the field of imaging, and more particularly, to medical imaging methods and devices.
Photon counting detectors have led human X-ray detection technology into a new era. Photon counting imaging can directly obtain energy levels of photons and the corresponding number of photons, thereby realizing multi-energy domain imaging, and broadening the prospect and development of the X-ray detection technology in the medical field.
However, under long-term irradiation the photon counting detector applied to the medical field causes the physical characteristics of a crystal of the photon counting detector and the charge response characteristics of a readout circuit of the photon counting detector to change, and causes the detector to generate a non-uniform counting response to incident X-rays, thereby affecting the imaging quality of medical images.
The present disclosure provides a medical imaging method and device, and an electronic apparatus, which can overcome the defect of the photon counting detector in the conventional art that the imaging quality of the medical image is affected by the photon counting detector under long-term irradiation.
A first aspect of the present disclosure provides a medical imaging method. The medical imaging method includes controlling, based on an emission cycle, a ray generator to emit a periodic imaging signal; emitting, based on a reset cycle, a reset signal for resetting, when the ray generator stops emitting the periodic imaging signal, a ray detector; controlling the reset ray detector to receive the periodic imaging signal; and performing, based on the received periodic imaging signal, image reconstruction to generate a medical image.
In the first aspect of the present disclosure, the medical imaging method further includes: determining a radiation intensity of the periodic imaging signal; and configuring, based on the radiation intensity, the reset cycle for the reset signal.
In the first aspect of the present disclosure, the reset cycle includes a reset time, and the configuring, based on the radiation intensity, the reset cycle for the reset signal includes: setting, when the radiation intensity is greater than or equal to a predetermined intensity threshold, the reset time of the reset cycle to be at a gap time following each emission of the periodic imaging signal.
In the first aspect of the present disclosure, the configuring, based on the radiation intensity, the reset cycle for the reset signal includes: setting, when the radiation intensity is less than the predetermined intensity threshold, the reset time of the reset cycle to be at a gap time following at least two consecutive emissions of the periodic imaging signal.
In the first aspect of the present disclosure, the ray generator includes a bulb tube. The controlling, based on the emission cycle, the ray generator to emit the periodic imaging signal includes: controlling, based on the emission cycle, the bulb tube to emit an imaging signal periodically, to generate the periodic imaging signal.
In the first aspect of the present disclosure, the ray generator includes a periodic shielding device, and a bulb tube configured to emit an image signal. The controlling, based on the emission cycle, the ray generator to emit the periodic imaging signal includes: controlling, based on the emission cycle, the periodic shielding device to shield the imaging signal emitted by the bulb tube periodically.
In the first aspect of the present disclosure, the medical imaging method further includes: determining, based on a predetermined first periodic pulse signal, the emission cycle; and determining, based on a predetermined second periodic pulse signal, the reset cycle, the second periodic pulse signal having an opposite phase to the first periodic pulse signal.
In the first aspect of the present disclosure, each of the first periodic pulse signal and the second periodic pulse signal is configured according to a user input, or automatically configured according to a user protocol.
In the first aspect of the present disclosure, the medical imaging method further includes: determining a radiation intensity of the periodic imaging signal; and adjusting, based on the radiation intensity, the emission cycle for the periodic imaging signal.
In the first aspect of the present disclosure, the adjusting, based on the radiation intensity, the emission cycle for the periodic imaging signal includes: adjusting, when the radiation intensity is greater than a preset intensity threshold, the periodic imaging signal to be emitted periodically at equal intervals; and adjusting, when the radiation intensity is less than or equal to the preset intensity threshold, the periodic imaging signal to be emitted periodically at varying intervals.
In the first aspect of the present disclosure, the performing, based on the received periodic imaging signal, the image reconstruction to generate the medical image includes: generating, based on the received periodic imaging signal, sparse sampling data; and reconstructing, by a reconstruction device, the sparse sampling data to generate the medical image.
In the first aspect of the present disclosure, the controlling the reset ray detector to receive the periodic imaging signal includes: determining, based on a predetermined first periodic pulse signal, a reception cycle for the periodic imaging signal; and controlling, based on the reception cycle, the reset ray detector to receive the periodic imaging signal.
A second aspect of the present disclosure provides a medical imaging device. The medical imaging device includes: a ray generator configured to emit, based on an emission cycle, a periodic imaging signal; a ray detector configured to receive the periodic imaging signal emitted by the ray generator; and a reset circuit connected to the ray detector, and configured to emit, based on a reset cycle, a reset signal for resetting, when the ray detector stops receiving the periodic imaging signal, the ray detector.
In the second aspect of the present disclosure, the medical imaging device further includes: a reconstruction device connected to the ray detector, and configured to perform, based on the received periodic imaging signal, image reconstruction to generate a medical image.
In the second aspect of the present disclosure, the ray generator is further configured to determine the emission cycle, and the reset circuit is further configured to determine the reset cycle.
In the second aspect of the present disclosure, the reset circuit is further configured to: set, when a radiation intensity of the periodic imaging signal is greater than or equal to a predetermined intensity threshold, a reset time of the reset cycle to be at a gap time following each emission of the periodic imaging signal; and set, when the radiation intensity is less than the predetermined intensity threshold, the reset time of the reset cycle to be at a gap time following at least two consecutive emissions of the periodic imaging signal.
In the second aspect of the present disclosure, the ray generator is further configured to: adjust, when a radiation intensity of the periodic imaging signal is greater than a preset intensity threshold, the periodic imaging signal to be emitted periodically at equal intervals; and adjust, when the radiation intensity is less than or equal to the preset intensity threshold, the periodic imaging signal to be emitted periodically at varying intervals.
In the second aspect of the present disclosure, the ray generator includes a bulb tube configured to emit, based on the emission cycle, the imaging signal periodically, to generate the periodic imaging signal.
In the second aspect of the present disclosure, the ray generator includes: a bulb tube configured to emit an image signal; and a periodic shielding device configured to shield, based on the emission cycle, the imaging signal emitted by the bulb tube periodically.
A third aspect of the present disclosure provides an electronic apparatus. The electronic apparatus includes a memory, a processor, and a computer program stored in the memory and executable on the processor. The computer program, when executed by the processor, causes the processor to perform the medical imaging method according to the first aspect.
A fourth aspect of the present disclosure provide a nonvolatile computer-readable storage medium having a computer program stored therein. The computer program, when executed by a processor, causes the processor to perform the medical imaging method according to the first aspect.
The present disclosure is further described below by way of exemplary embodiments, but the present disclosure is not therefore limited to the scope of the described embodiments.
Referring to
The imaging signal may be an X-ray, but is not limited to the X-ray. The imaging signal may be selected from a variety of rays for imaging according to actual imaging requirements. The ray generator emits the periodic imaging signal based on the emission cycle. Each emission cycle includes an emission time when the periodic imaging signal is emitted and a gap time when the emission of the periodic imaging signal is stopped. The emission cycle repeats to complete a medical imaging for a subject to be imaged.
In this embodiment, the problem of inconsistent charge response caused by a long period of continuous operation of the ray detector is avoided by periodically emitting the imaging signal, and the impact of residual charge on the ray detector is eliminated during the gap time when the emission cycle is stopped, thereby restoring the ray detector to its initial state.
In some embodiments, the determining the emission cycle in step S101 specifically includes: determining the emission cycle for the imaging signal based on a predetermined first periodic pulse signal.
The first periodic pulse signal is generated by a pulse generating circuit, and the first periodic pulse signal acts on the ray generator. The pulse generating circuit may be built in an internal circuit of the ray generator, or may be arranged outside the ray generator.
In an implementation, the first periodic pulse signal may be configured according to a user input, and parameters for the pulse characteristics of the first periodic pulse signal are configured by the pulse generating circuit. The pulse characteristics include: a pulse shape, a pulse width, or a duty cycle of the pulse. A user may directly select one or more of the above pulse characteristics for parameter configuration.
In an implementation, the first periodic pulse signal may be automatically configured according to a user protocol. The user protocol is determined before performing the medical imaging of the subject to be imaged. The user protocol includes an integration time per field of view for each ray detector to acquire the periodic imaging signal, a current value, and a voltage value, etc., configured at the ray generator. The pulse generating circuit selects the parameters for the pulse characteristics that adaptively match the user protocol, and then the pulse generating circuit generates a corresponding periodic pulse signal according to the parameters for the pulse characteristics. Specifically, a single pulse duration of the first periodic pulse signal is obtained according to the integration time per field of view, and it is determined whether a value of the current parameter setting exceeds a threshold value for switching the pulse period scheme according to a bulb tube voltage value and a bulb tube current value.
It should be noted that, referring to
In some embodiments, the ray generator includes a bulb tube. The controlling, based on the emission cycle, the ray generator to emit the periodic imaging signal in step S101 specifically includes: controlling the bulb tube to periodically emit an imaging signal based on the emission cycle to generate the periodic imaging signal.
In an implementation, the bulb tube is controlled by the first periodic pulse signal to periodically emit the imaging signal to generate the periodic imaging signal. When the pulse level of the first periodic pulse signal is high, the bulb tube is controlled to emit the periodic imaging signal once. When the pulse level of the first periodic pulse signal is low, the bulb tube is controlled to stop emitting the periodic imaging signal.
In some embodiments, the ray generator includes a periodic shielding device and a bulb tube. The controlling, based on the emission cycle, the ray generator to emit the periodic imaging signal in step S101 specifically includes: controlling the periodic shielding device to periodically shield the imaging signal emitted by the bulb tube based on the emission cycle.
In an implementation, the bulb tube is controlled to emit the imaging signal, and the periodic shielding device is controlled by the first periodic pulse signal to periodically shield the imaging signal emitted by the bulb tube to generate the periodic imaging signal. When the pulse level of the first periodic pulse signal is high, the periodic shielding device is controlled not to shield the periodic imaging signal emitted by the bulb tube. When the pulse level of the first periodic pulse signal is low, the periodic shielding device is controlled to shield the periodic imaging signal emitted by the bulb tube.
Referring to
The reset signal is generated by a reset circuit, and the reset signal acts on the ray detector to reduce the residual charge on the ray detector. Generally, the ray detector may gradually return to the initial state after stopping receiving the imaging signal, and a recovery time is as long as tens of minutes. Therefore, the recovery of the ray detector to the initial state may be further accelerated by the reset signal. The reset circuit emits the reset signal based on the reset cycle. Each reset cycle includes a reset time when the reset signal is emitted and a stop time when the emission of the reset signal is stopped. The reset cycle repeats to complete the medical imaging of the subject to be imaged.
During the action of the reset signal, the ray detector does not receive the periodic imaging signal and does not generate imaging data, thus avoiding a negative impact of the reset signal on the imaging data of the ray detector, which makes an imaging result of a medical image inaccurate, and thus affects a subsequent use of the medical image. The ray detector is reset after receiving the reset signal, so that the responsiveness of the ray detector to the imaging signal is restored to the initial state.
In some embodiments, the reset signal may include a reset pulse signal or an interference energy signal. The interference energy signal includes but is not limited to: any one or more of thermal energy, electromagnetic wave, ultraviolet light, visible light, or infrared light. When the reset signal is the reset pulse signal, the reset circuit may be built in an internal circuit of the ray detector. When the reset signal is the interference energy signal, the reset circuit may be arranged outside the ray detector.
In some embodiments, the reset circuit applies the reset signal to the ray detector during an intermittent time when the ray generator stops emitting the periodic imaging signal, or applies the reset signal to the ray detector during an intermittent time when the ray detector stops receiving the periodic imaging signal, thereby accelerating the recovery process of the ray detector.
Taking the photon counting CT equipment as an example,
In some embodiments, the determining the reset cycle in step S102 specifically includes: determining the reset cycle for the reset signal based on a predetermined second periodic pulse signal. The second periodic pulse signal has an opposite phase to the first periodic pulse signal. The second periodic pulse signal is generated by the pulse generating circuit, and the second periodic pulse signal acts on the reset signal.
In an implementation, the second periodic pulse signal may be set to have an opposite phase to the first periodic pulse signal, but have the same parameters for other pulse characteristics as the first periodic pulse signal.
In an implementation, the second periodic pulse signal may be configured according to a user input, and the parameters for the pulse characteristics of the second periodic pulse signal are configured by the pulse generating circuit. The pulse characteristics include: a pulse shape, a pulse width, or a duty cycle of the pulse.
In an implementation, the second periodic pulse signal may be automatically configured according to a user protocol. The user protocol is determined before the medical imaging of the subject to be imaged. The user protocol includes an integration time per field of view for each ray detector to acquire the periodic imaging signal, a current value, and a voltage value, etc., configured at the ray generator. The pulse generating circuit selects the parameters of the pulse characteristics that adaptively match the user protocol, and then the pulse generating circuit generates a corresponding periodic pulse signal according to the parameters of the pulse characteristics. Specifically, a single pulse duration of the first periodic pulse signal is obtained according to the integration time per field of view, and it is determined whether a value of the current parameter setting exceeds a threshold value for switching the pulse period scheme according to a bulb tube voltage value and a bulb tube current value.
In some embodiments, the determining the reset cycle for the reset signal in step S102 specifically includes: determining a radiation intensity of the periodic imaging signal, and configuring the reset cycle for the reset signal based on the radiation intensity.
In an implementation, the ray intensity of the periodic imaging signal may be determined based on the periodic imaging signal acquired in real time. Specifically, real-time acquisition can be performed in the following ways. Firstly, the periodic imaging signal received by the ray generator is acquired in real time. Secondly, the ray intensity is determined based on a current intensity of the periodic imaging signal emitted by the ray generator, and the stronger the current intensity is, the stronger the ray intensity of the imaging signal is, and vice versa. Different ray intensities act on the ray detector, causing the ray detector to generate a deteriorated response for different lengths of time. The stronger the ray intensity, the easier it is for the ray detector to reach an undesirable state where the deteriorated response is generated. Therefore, when the ray intensity becomes stronger, the reset time and emission frequency of the reset signal need to be increased.
In an implementation, the ray intensity of the periodic imaging signal may be determined according to a user protocol. The user protocol is determined before the medical imaging of the subject to be imaged. The user protocol includes a current value, and a voltage value, etc., configured at the ray generator. The ray intensity of the periodic imaging signal may be determined according to the current configured at the ray generator.
In an implementation, the configuring, based on the radiation intensity, the reset cycle for the reset signal specifically includes the following steps.
When the radiation intensity is greater than or equal to a predetermined intensity threshold, the reset time of the reset cycle is configured to be at a gap time following each emission of the periodic imaging signal. The intensity threshold may be configured according to an actual application scenario. It can further be understood that, referring to
When the radiation intensity is less than the predetermined intensity threshold, the reset time of the reset cycle is configured to be at a gap time following at least two consecutive emissions of the periodic imaging signal. It can be further understood that, referring to
In some embodiments, the emission cycle of the periodic imaging signal may also be adjusted according to the ray intensity.
When the ray intensity is greater than a predetermined intensity threshold, the periodic imaging signal is configured to be emitted periodically at equal intervals. That is, the emission time for each emitting the periodic imaging signal in
When the ray intensity is less than or equal to the predetermined intensity threshold, the periodic imaging signal is configured to be periodically emitted at varying intervals. That is, the emission time for each emitting the periodic imaging signal in
In this embodiment, by matching the reset cycle for the reset signal with the emission cycle for the periodic imaging signal, the ray detector can be restored from the state where the deteriorated response is generated in time without affecting the imaging result, and the imaging quality of the medical image can be improved.
Referring to
In some embodiments, the ray detector generates sparse sampling data based on the received periodic imaging signal, and the sparse sampling data is reconstructed by a reconstruction device to generate the medical image. The reconstruction device may be integrated with the ray detector, or separated to the ray detector. And the reconstruction device may be implemented as hardware, for example, at least part of an application specific integrated circuit, or software, for example, program instructions executable by at least one processor.
In some embodiments, the ray detector may receive the periodic imaging signal based on a reception cycle. Referring to
In some embodiments, the reception cycle for the periodic imaging signal is determined based on a predetermined first periodic pulse signal. The first periodic pulse signal is generated by the pulse generating circuit, and the first periodic pulse signal acts on the ray generator.
In some embodiments, a sparse sampling reconstruction algorithm is a technology that uses an energy attenuation of the imaging signal to calculate and image. The traditional reconstruction algorithm needs to use complete projection data of the imaging signal to obtain an ideal reconstruction result, while the sparse sampling reconstruction algorithm does not need to obtain complete projection data of the imaging signal. The algorithms used for the reconstruction of the sparse sampling data in the reconstruction device include, but are not limited to, a K-space weighted image contrast (KWIC) reconstruction scheme, a projection window sharing reconstruction technology, a compressed sensing sparse reconstruction technology, or a deep learning neural network reconstruction technology.
According to the above medical imaging method, the impact of the charge accumulation of the ray detector on the imaging quality of the medical image can be eliminated by periodically emitting the imaging signal based on an emission cycle. In addition, the reset signal is emitted to reset the state of the ray detector during the imaging interval of the periodic imaging signal, so as to accelerate the recovery of the ray detector, thereby improving the efficiency and quality of the medical imaging and ensuring the stability of the medical imaging device.
An exemplary system to which the above-described medical imaging method is applied is described in detail below with reference to
The user inputs imaging requirements of the subject to be imaged into the pulse generating circuit. The pulse generating circuit selects parameters for the pulse characteristics that adaptively match the imaging requirements, and the pulse generating circuit generates corresponding first periodic pulse signal and second periodic pulse signal based on the parameters for the pulse characteristics.
The first periodic pulse signal acts on the ray generator and the ray detector, respectively. Under the action of the first periodic pulse signal, the ray generator emits the periodic imaging signal based on the emission cycle, and the ray detector receives the periodic imaging signal based on the reception cycle. The emission cycle and the reception cycle match each other to avoid missing the imaging signal and affecting the accuracy and completeness of imaging of the medical image.
The second periodic pulse signal acts on the reset circuit. Under the action of the second periodic pulse signal, the reset circuit emits the reset signal to a detection crystal of the ray detector based on the reset cycle, so as to eliminate the residual charge on the detection crystal and accelerate the recovery of the ray detector to the initial state.
The reset signal and the periodic imaging signal are alternately emitted to the ray detector, and the reset circuit emits the reset signal only during the gap time when the ray generator stops emitting the periodic imaging signal. The specific reset cycle for the reset signal may be configured based on the periodic imaging signal. The stronger the intensity of the periodic imaging signal, the longer the reset time of the reset signal, and the higher the reset frequency of the reset signal. The weaker the intensity of the periodic imaging signal, the shorter the reset time of the reset signal, and the lower the reset frequency of the reset signal.
In step S201, a ray generator is controlled to emit a periodic imaging signal based on an emission cycle.
In this step, the ray generator emits the periodic imaging signal based on the emission cycle. The emission cycle is determined based on a first periodic pulse signal generated by a pulse generating circuit. As described above, the first periodic pulse signal may be configured according to a user input, or may be automatically configured according to a user protocol.
In step S202, the reset signal is emitted based on a reset cycle. The reset signal is used to reset a ray detector when the ray generator stops emitting the periodic imaging signal.
In this step, the reset signal is emitted by, for example, a reset circuit in accordance with a reset cycle. The reset cycle is determined based on a second periodic pulse signal generated by the pulse generating circuit. As described above, the second periodic pulse signal may be configured according to a user input, or may be automatically configured according to a user protocol.
In step S203, the reset ray detector is controlled to receive the periodic imaging signal, and image reconstruction is performed based on the received periodic imaging signal.
For details of the steps of the medical imaging method in this embodiment, reference may be made to the description made above with respect to the medical imaging method shown in
In some embodiments, the reset circuit 93 is further configured to: set, when a radiation intensity of the periodic imaging signal is greater than or equal to a predetermined intensity threshold, a reset time of the reset cycle to be at a gap time following each emission of the periodic imaging signal; and set, when the radiation intensity is less than the predetermined intensity threshold, the reset time of the reset cycle to be at a gap time following at least two consecutive emissions of the periodic imaging signal. The ray generator 92 is further configured to: adjust, when a radiation intensity of the periodic imaging signal is greater than a preset intensity threshold, the periodic imaging signal to be emitted periodically at equal intervals; and adjust, when the radiation intensity is less than or equal to the preset intensity threshold, the periodic imaging signal to be emitted periodically at varying intervals.
As for the device embodiment, since it substantially corresponds to the method embodiment, reference may be made to a partial description of the method embodiment. The above-described device embodiments are merely illustrative. The units described as separate components may or may not be physically separate, and the components shown as units may or may not be physical units. That is, they may be located in one place, or may be distributed on a plurality of network units. Some or all of these modules may be selected according to actual needs to achieve the purpose of the solution of the present disclosure. A person of ordinary skill in the art may understand and implement the embodiments without any creative effort.
As shown in
The bus 103 includes a data bus, an address bus, and a control bus.
The memory 102 may include a volatile memory, such as a random-access memory (RAM) 1021 and/or a cache memory 1022, and may further include a read-only memory (ROM) 1023.
The memory 102 may also include a program tool 1025 (or a utility) having at least one set of program modules 1024. The program modules 1024 include, but are not limited to: an operating system, one or more applications, other program modules, and program data. Each or some combination of these examples may include an implementation of a network environment.
The processor 101 executes various functional applications and data processing by running computer programs stored in the memory 102, such as the method according to any of the above embodiments.
The electronic apparatus 100 may also communicate with one or more external apparatuses 104 through an input/output (I/O) interface 105. Moreover, the modularized electronic apparatus 100 may also communicate with one or more networks (e.g., a local area network (LAN), a wide area network (WAN), and/or a public network, such as the Internet) through a network adapter 107. As shown, the network adapter 107 communicates with other modules of the model-generated electronic apparatus 100 via the bus 103. It should be understood that, although not shown in the figures, other hardware and/or software modules may be used in conjunction with the model-generated electronic apparatus 100, including but not limited to: a microcode, a device driver, a redundant processor, an external disk drive array, a redundant array of independent disks (RAID), a tape drive, and a data backup storage system, etc.
It should be noted that although several units/modules or sub-units/modules of the electronic apparatus are mentioned in the above detailed description, this division is only exemplary and not mandatory. Indeed, according to embodiments of the present disclosure, the features and functions of two or more units/modules described above may be embodied in one unit/module. Conversely, the features and functions of one unit/module described above may be further divided to be embodied by a plurality of units/modules.
The embodiments of the present disclosure also provide a computer-readable storage medium, having a computer program stored therein. The computer program, when executed by a processor, implements the method according to any of the above embodiments.
More specifically, the readable storage medium may include, but is not limited to: a portable disk, a hard disk, a random-access memory, a read-only memory, an erasable programmable read-only memory, an optical storage device, a magnetic storage device, or any suitable combination of the above.
In an implementation, the embodiments of the present disclosure may also be implemented in the form of a program product including a program code. When the program product is run on a terminal device, the program code is configured to cause the terminal device to execute the method according to any of the above embodiments.
The program code for executing the present disclosure may be written in any combination of one or more programming languages. The program code may be executed entirely on the user's device, partly on the user's device, as a stand-alone software package, partly on the user's device and partly on a remote device, or entirely on the remote device.
Although specific embodiments of the present disclosure have been described above, a person skilled in the art will understand that these are only examples and the protection scope of the present disclosure is defined by the appended claims. The person skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present disclosure, but these changes and modifications all fall within the protection scope of the present disclosure.
Number | Date | Country | Kind |
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202211738761.8 | Dec 2022 | CN | national |