Claims
- 1. A packaged medicinal product having extended shelf-life comprising:
(a) a medicinal preparation; and (b) a plastic container having a fluorinated barrier layer on a surface of the body wall, wherein the body of the container is fill with the medicinal preparation.
- 2. A packaged medicinal product according to claim 1, wherein the medicinal preparation is a liquid.
- 3. A packaged medicinal product according to claim 2, wherein the medicinal preparation comprises a highly potent ingredient.
- 4. A packaged medicinal product according to claim 3, wherein the highly potent ingredient is a prostaglandin.
- 5. A packaged medicinal product according to claim 1, wherein the container is made of materials comprising LDPE, HDPE or PP.
- 6. A packaged medicinal product according to claim 5, wherein the container is a small volume bottle.
- 7. A packaged medicinal product according to claim 6, wherein the medicinal preparation comprises a prostaglandin.
- 8. A packaged medicinal product according to claim 7, which is for ophthalmic use.
- 9. A method of packaging a medicinal preparation, said method comprising the steps of:
(a) providing a plastic container having a fluorinated barrier layer on a surface of its body wall; and (b) filling the container body with the medicinal preparation.
- 10. The method according to claim 9, wherein the medicinal preparation is a liquid.
- 11. The method according to claim 10, wherein the medicinal preparation comprises a highly potent ingredient.
- 12. The method according to claim 11, wherein the highly potent ingredient is a prostaglandin.
- 13. The method according to claim 9, wherein the container is made of materials comprising LDPE, PP, HDPE.
- 14. The method according to claim 13, wherein the container is a small volume bottle.
- 15. The method according to claim 14, wherein the medicinal preparation comprises a prostaglandin.
- 16. The method according to claim 15, wherein the medicinal preparation is for ophthalmic use.
- 17. A method of increasing the stability of a liquid medicinal preparation, said method comprising packaging the liquid medicinal preparation in a plastic container having a fluorinated barrier layer on a surface of the container body wall.
- 18. The method according to claim 17, wherein the plastic container is made of materials comprising LDPE, PP, HDPE.
- 19. The method according to claim 18, wherein the liquid medicinal preparation comprises a highly potent ingredient.
- 20. The method according to claim 19, wherein the highly potent ingredient is a prostaglandin.
- 21. The method according to claim 20, wherein the medicinal preparation is for ophthalmic use.
- 22. A method of preventing loss of an ingredient in a liquid medicinal preparation through the wall of a plastic container which contains the medicinal preparations, said method comprising packaging the medicinal preparation in the plastic container said container having has a fluorinated barrier layer on a surface of the container body wall.
- 23. The method according to claim 22, wherein the plastic container is made of materials comprising LDPE, PP, HDPE.
- 24. The method according to claim 22, wherein the liquid medicinal preparation comprises a highly potent ingredient.
- 25. The method according to claim 24, wherein the highly potent ingredient is a prostaglandin.
- 26. The method according to claim 25, wherein the medicinal preparation is for ophthalmic use.
- 27. The method according to claim 22, wherein the container has a fluorinated barrier layer on the inside surface of the container body wall.
- 28. A method of reducing transfer of an impurity into a liquid medicinal preparation upon storage, comprising packaging the liquid medicinal preparation in a plastic container said container having a fluorinated barrier layer on a surface of the container body wall.
- 29. The method according to claim 28, wherein the plastic container is made of materials comprising LDPE, PP, HDPE.
- 30. The method according to claim 28, wherein the liquid medicinal preparation comprises a highly potent ingredient.
- 31. The method according to claim 30, wherein the highly potent ingredient is a prostaglandin.
- 32. The method according to claim 31, wherein the medicinal preparation is for ophthalmic use.
- 33. The method according to claim 28, wherein the container has a fluorinated barrier layer on the inside surface of the container body wall.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application claims the benefit of provisional U.S. patent application Serial No. 60/406,848, filed Aug. 29, 2002.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60406848 |
Aug 2002 |
US |