MEMANTINE FOR THE NORMALIZATION OF VISUAL ACUITY DEFICITS

Abstract

A method for the treatment of disturbance of visual function which comprises administering a pharmaceutically effective amount of memantine to a patient in need of treatment of said disturbance.

Description

DESCRIPTION OF THE DRAWING FIGURE

The FIGURE shows the visual acuity of rabbits treated with memantine or a placebo after a period of having elevated intraocular pressure (IOP).

Claims

1. A method for the treatment of disturbance of visual function which comprises administering a pharmaceutically effective amount of memantine to a patient in need of treatment of said disturbance.

2. The method according to claim 1, comprising local administration of memantine or a salt thereof to the eye.

3. The method according to claim 1, comprising administering memantine or a salt thereof in the form of a liquid preparation.

4. The method according to claim 3, comprising administering the memantine or a salt thereof in the form of an ophthalmic solution.

5. The method according to claim 4, wherein the ophthalmic solution is an aqueous ophthalmic solution.

6. The method according to claim 3, comprising administering memantine or a salt thereof in the form of an injection.

7. The method according to claim 5 comprising administering memantine or a salt thereof in the presence of a solubilizer.

8. The method according to claim 1 comprising systemically administering memantine or a salt thereof in the form of a solution.

9. The method according to claim 7 wherein said memantine or salt thereof is administered orally.

10. The method according to claim 1 comprising administering a pharmaceutical preparation containing memantine or a salt thereof in a concentration of 0.01-2.0 (W/V) %.

11. The method of claim 1 wherein said disturbance of visual function is a result of injury to the outer retina causing visual acuity deficits.

12. The method of claim 11 wherein said treatment results in an improvement in reading a Snellen Eye Chart of at least one line.