Membrane-Acting Peptides

Information

  • Research Project
  • 10114789
  • ApplicationId
    10114789
  • Core Project Number
    R15GM140421
  • Full Project Number
    1R15GM140421-01
  • Serial Number
    140421
  • FOA Number
    PAR-18-714
  • Sub Project Id
  • Project Start Date
    9/15/2020 - 4 years ago
  • Project End Date
    8/31/2023 - a year ago
  • Program Officer Name
    FABIAN, MILES
  • Budget Start Date
    9/15/2020 - 4 years ago
  • Budget End Date
    8/31/2023 - a year ago
  • Fiscal Year
    2020
  • Support Year
    01
  • Suffix
  • Award Notice Date
    9/14/2020 - 4 years ago

Membrane-Acting Peptides

Membrane-Acting Peptides Bioactive peptides regulate many physiological processes, acting at some sites as endocrine or paracrine signals and at others as neurotransmitters or growth factors, have important and positive impacts on human health including antimicrobial, antifungal, antiviral, and antitumor activities. In this project, we will explore a new rationale design approach to membrane-acting peptides. We will: 1) design and develop new bioactive peptides based on on-membrane peptide assembly; 2) study the biological implications of peptides in vitro; 3) evaluate the pharmaceutical significance of promising peptides on disease cells and co-cultures.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R15
  • Administering IC
    GM
  • Application Type
    1
  • Direct Cost Amount
    300000
  • Indirect Cost Amount
    162600
  • Total Cost
    462600
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    859
  • Ed Inst. Type
    BIOMED ENGR/COL ENGR/ENGR STA
  • Funding ICs
    NIGMS:462600\
  • Funding Mechanism
    Non-SBIR/STTR RPGs
  • Study Section
    BBM
  • Study Section Name
    Biochemistry and Biophysics of Membranes Study Section
  • Organization Name
    STEVENS INSTITUTE OF TECHNOLOGY
  • Organization Department
    CHEMISTRY
  • Organization DUNS
    064271570
  • Organization City
    HOBOKEN
  • Organization State
    NJ
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    070305906
  • Organization District
    UNITED STATES