Claims
- 1. A compound of the formula ##STR8## where Z is halogen;
- R.sub.1 is phenyl or loweralkylphenyl; and
- R.sub.2 is loweralkyl or cycloalkyl;
- the 3aS-cis isomer or the 3aR-cis isomer thereof or a mixture of the two isomers including the racemic mixture, or a pharmaceutically acceptable acid addition salt thereof.
- 2. A pharmaceutical composition comprising a compound as defined in claim 1 in an amount effective for alleviating a memory dysfunction characterized by a cholinergic deficit or for alleviating pain and a suitable carrier therefor.
- 3. A method of treating a patient in need of relief from a memory dysfunction characterized by a cholinergic deficit which comprises administering to such a patient an effective amount of a compound as defined in claim 1.
- 4. A method of treating a patient in need of relief from pain which comprises administering to such a patient an effective amount of a compound as defined in claim 1.
Parent Case Info
This is a continuation of a prior application Ser. No. 443,682, filed Nov. 30, 1989 now U.S. Pat. No. 5,077,289.
US Referenced Citations (5)
Foreign Referenced Citations (2)
Number |
Date |
Country |
154864 |
Sep 1985 |
EPX |
298202 |
Jan 1989 |
EPX |
Non-Patent Literature Citations (5)
Entry |
Brossi, specification of SN166824. |
Yu, Heterocycles 27, 745 (1988). |
Yu, FEBS Letters 234, 127, 130 (1988). |
Atack, J. Pharm. Exp. Ther. 249 194-202. |
Fritz, Tetrahedron 26, 5821 (1970). |
Continuations (1)
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Number |
Date |
Country |
Parent |
443682 |
Nov 1989 |
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