Claims
- 1. An intermediate compound for preparing a penem derivative, represented by the following general formula:
- HS--R.sub.3
- wherein R.sub.3 is a bicycloheterocyclic group selected from the group consisting of: ##STR131## wherein R.sub.4 represents: a hydrogen,
- a halogen,
- an amino,
- a hydroxyl,
- an alkyl having from 1 to 4 carbon atoms,
- a cyclopropylmethyl,
- a cyclobutylmethyl,
- a 2-propen-1-yl,
- a 2-propyn-1-yl,
- a 2-halogenoethyl,
- a phenylmethyl,
- a 4-halogenophenylmethyl,
- a cyanomethyl,
- a carboxymethyl,
- an alkyloxycarbonylmethyl of from 1 to 4 carbon atoms in its alkyl moiety,
- an alkyloxycarbonylmethylcarbonylmethyl of from 1 to 4 carbon atoms in its alkyl moiety
- an acetylmethyl,
- a benzoylmethyl,
- a carbamoylmethyl or a 2-carbamoylethyl,
- an N-alkylcarbamoylmethyl or 2-(N-alkylcarbamoyl)ethyl of from 1 to 3 carbon atoms in its alkyl moiety,
- an N,N-dialkylcarbamoylmethyl or 2-(N,N-dialkylcarbamoyl)-ethyl of from 1 to 3 carbon atoms in its alkyl moiety, or
- an N-methyltetrazolyl-5-yl-thiomethyl, or
- a pharmaceutically acceptable salt thereof.
- 2. An intermediate compound as set forth in claim 1 wherein the salt is an alkali metal salt.
Priority Claims (2)
Number |
Date |
Country |
Kind |
60-131394 |
Jun 1985 |
JPX |
|
60-213420 |
Sep 1985 |
JPX |
|
Parent Case Info
This is a divisional, of application Ser. No. 038,640, filed Apr. 15, 1987 now abandoned, which is a CIP of Ser. No. 875,228 filed June 17, 1986, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4748162 |
Leanza et al. |
May 1988 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
210883 |
Feb 1987 |
EPX |
63-154691 |
Jun 1988 |
JPX |
Non-Patent Literature Citations (2)
Entry |
Chemical Abstracts vol. 110:75160a, Takemura et al., JP 63, 154,691 (1987). |
Chemical Abstract vol. 106:213640c, Sato et al., EP 210,883 (1987). |
Divisions (1)
|
Number |
Date |
Country |
Parent |
38640 |
Apr 1987 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
875228 |
Jun 1986 |
|