Claims
- 1. A compound having the formula: ##STR25## wherein: X.sub.1 and X.sub.2 are H or .dbd.O, but both are not .dbd.O;
- X.sub.3 and X.sub.4 are H or .dbd.O, but both are not .dbd.O;
- A is H, alkyl group of C.sub.6 or less, --CH.sub.2 --CH.sub.2 --S--R.sub.1, or --CO--CH.sub.2 --S--R.sub.1, with the proviso that when X.sub.1 or X.sub.2 is .dbd.O, A is H;
- A' is H, alkyl group of C.sub.6 or less, --CH.sub.2 --CH.sub.2 --S--R.sub.2, or --CO--CH.sub.2 --S--R.sub.2, with the proviso that when X.sub.3 or X.sub.4 is .dbd.O, A' is H;
- Y is
- (a) --CH.sub.2 --S--R.sub.3, or H, when A is H or an alkyl group of C.sub.6 or less and A' is H or an alkyl group of C.sub.6 or less, or
- (b) H, with the proviso that Y must be selected from (a) when A is H or an alkyl group of C.sub.6 or less and A' is H or an alkyl group of C.sub.6 or less;
- Y' is
- (a) --CH.sub.2 --S--R.sub.4, or H, when A is H or an alkyl group of C.sub.6 or less and A' is H or an alkyl group of C.sub.6 or less, with the proviso that Y and Y' are not both H, or
- (b) H, with the proviso that Y' must be selected from (a) when A is H or an alkyl group of C.sub.6 or less and A' is H or an alkyl group of C.sub.6 or less;
- R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6 are independently selected from sulfur protecting groups;
- Q is H or a polar group;
- n is 0 to 2; and
- Z is --(W).sub.m --R', where W is --CH.sub.2 --, --CH.sub.2 --O--, --CH.sub.2 --CO--, or combinations thereof, m is 0 to 5, and R' is a conjugation group, with the provisos that when Z is attached to the carbon designated .alpha. there is either no X.sub.1 or no Q at .alpha., that when Z is attached to the carbon designated .beta. there is either no X.sub.3 or no Q at .beta., that when X.sub.1 is .dbd.O there is no Z at .alpha., and that when X.sub.3 is .dbd.O there is no Z at .beta..
- 2. The compound of claim 1 wherein said compound has the formula: ##STR26##
- 3. The compound of claim 1 wherein said compound has the formula: ##STR27##
- 4. The compound of claim 1 wherein said compound has the formula: ##STR28##
- 5. The compound of claim 1 wherein said compound has the formula: ##STR29##
CROSS REFERENCE TO RELATED APPLICATION
This application is a division of Ser. No. 07/589,449, filed Sep. 27, 1990, issued Dec. 24, 1991, as U.S. Pat. No. 5,075,099, which is a division of Ser. No. 07/201,134, filed May 31, 1988, issued Jan. 29, 1991, as U.S. Pat. No. 4,988,496.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
4914241 |
Hesse et al. |
Apr 1990 |
|
4987130 |
Tsushima et al. |
Jan 1991 |
|
5196550 |
Long, III et al. |
Mar 1993 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
188256 |
Jul 1986 |
EPX |
Non-Patent Literature Citations (3)
Entry |
Greene, Protective Groups in Organic Synthesis, Chapter 6, pp. 914-196, 1981. |
Yano et al., "4-Substituted 1,2-dithiolane derivatives," Jap. Pat. No. 61,103,880 (May 22, 1986) as abstracted in CA105:208855. |
Bal et al., Rocz. Chem. 50(5):961-6 as abstracted in CA86:29452, 1976. |
Divisions (2)
|
Number |
Date |
Country |
Parent |
589449 |
Sep 1990 |
|
Parent |
201134 |
May 1988 |
|