Claims
- 1. A method comprising:
delivering a prepolymer composition to a vascular site in a blood vessel; introducing an activator to said vascular site; wherein said introducing at least partially polymerizes said prepolymer composition in situ thereby embolizing said blood vessel.
- 2. A method according to claim 1, wherein:
said activator comprises at least one type of electromagnetic radiation chosen from gamma rays, X-rays, ultraviolet waves, light waves, infrared waves, and radio waves.
- 3. A method according to claim 1, wherein:
said activator comprises a magnetic field.
- 4. A method according to claim 1, wherein:
said activator comprises a composition.
- 5. A method according to claim 1, wherein:
said activator comprises ultrasound energy.
- 6. An apparatus comprising:
a catheter to deliver a prepolymer to a vascular site in a blood vessel wherein said prepolymer is adapted to at least partially polymerize in situ by introducing an activator thereby embolizing said blood vessel, wherein said catheter is adapted to at least partially adhere to said polymerized prepolymer.
- 7. An apparatus according to claim 6, wherein:
said catheter is adapted to introduce said activator.
- 8. An apparatus according to claim 7, further comprising
a fiber optic to introduce light waves to said vascular site.
- 9. An apparatus according to claim 7, further comprising
a heating element to introduce infrared waves to said vascular site.
- 10. An apparatus according to claim 7, further comprising
a heating fluid to introduce a temperature change to said vascular site.
- 11. An apparatus according to claim 6, wherein:
said activator is not introduced by said catheter.
- 12. An apparatus according to claim 11, further comprising
an instrument to deliver focused ultrasound to said vascular site.
- 13. An apparatus according to claim 11, further comprising
an instrument to deliver eddy currents to said vascular site.
- 14. An apparatus according to claim 11, further comprising
an instrument to deliver a magnetic field to said vascular site.
- 15. An apparatus according to claim 11, further comprising
an instrument to deliver electromagnetic radiation to said vascular site.
- 16. A composition comprising:
a prepolymer, wherein said prepolymer is adapted to at least partially polymerize in situ by introducing an activator thereby embolizing a vascular site in a blood vessel.
- 17. A composition according to claim 16, wherein:
said prepolymer comprises a light-activated cross-linking material.
- 18. A composition according to claim 16, wherein:
said prepolymer comprises a heat-activated cross-linking material.
- 19. A composition according to claim 16, wherein:
said prepolymer is contained within microbeads.
- 20. A composition according to claim 19, wherein:
said microbeads comprise magnetic particles.
- 21. A composition according to claim 20, wherein:
said magnetic particles adapted to heating by at least one external field chosen from a electromagnetic field, radio waves, and an microwaves.
- 22. A composition according to claim 19, wherein:
said microbeads comprise a catalyst to polymerize said prepolymer.
- 23. A composition comprising:
a first material, said first material adapted to at least partially polymerize in situ thereby embolizing a blood vessel, a second material, said second material adapted to initiate said polymerization, wherein said first material is at least one form chosen from a solution, a gel, and a foam.
- 24. A composition according to claim 23, wherein:
said second material comprises a catalyst.
- 25. A composition according to claim 24, wherein:
said catalyst comprises an acid or base.
- 26. A composition according to claim 24, wherein:
said catalyst comprises plasticizers.
- 27. A composition comprising:
a prepolymer adapted to at least partially polymerize in situ thereby embolizing a blood vessel, wherein said prepolymer has a temperature above said blood vessel, such that introducing said prepolymer to a vascular site of said blood vessel polymerizes said prepolymer.
- 28. A composition comprising:
a prepolymer, and a radio opaque agent comprising at least one metal, whereby said agent absorbs electromagnetic radiation thereby heating said prepolymer to at least partially polymerize said prepolymer thereby embolizing a blood vessel.
- 29. A composition according to claim 28, wherein:
said agent comprises tantalum powder.
- 30. An apparatus comprising:
a catheter to deliver a prepolymer to a vascular site in a blood vessel; and a fiber opticwherein said fiber optic is detachably connected to said catheter, whereby said prepolymer is adapted to at least partially polymerize in situ by introducing light waves from said fiber optic.
- 31. An apparatus comprising:
a catheter; a heating element; and a temperature sensing element, wherein said temperature sensing element provides temperature feedback to avoid at least partially polymerizing a prepolymer delivered by said catheter.
- 32. An apparatus according to claim 31, wherein:
said heating element is positioned within said catheter.
- 33. An apparatus according to claim 32, wherein
said temperature sensing element is positioned within said catheter, distally to said heating element.
- 34. An apparatus comprising:
a catheter comprising (i) an inner dissolved polymer stream, and (ii) an outer flush stream, wherein said flush steam is adapted to remove a solvent from said dissolved polymer to cause said dissolved polymer to precipitate.
- 35. An apparatus according to claim 34, wherein said flush stream is further adapted to maximize an interface between said dissolved polymer and said flush steam distal to said catheter.
- 36. A composition comprising:
a liquid embolic solution; and fibers, said fibers are adapted to anchor said liquid embolic solution to a vascular site in a blood vessel.
- 37. An apparatus comprising:
a catheter; and a detachable catheter tip, wherein said catheter tip can be detached by an operator through a mechanically activated or heat activated detachment link.
- 38. A composition comprising:
a liquid embolic solution; and a blood-soluble gas, wherein said composition forms a foam for delivery of said liquid embolic solution to a vascular site in a blood vessel.
- 39. A composition according to claim 38, wherein said gas is carbon dioxide.
- 40. An apparatus comprising:
a catheter comprising a first channel for delivery of a dissolved polymer to a vascular site in a blood vessel, and a second channel for delivery of a material adapted to accelerate precipitation of said dissolved polymer.
- 41. A composition according to claim 40, wherein said second channel delivers said material inside the dissolved polymer to begin precipitation from within the dissolved polymer.
- 42. A composition according to claim 40, wherein said second channel delivers said material outside the dissolved polymer to diffuse a solvent out of the dissolved polymer.
- 43. A method comprising:
delivering a first material to a vascular site in a blood vessel to promote cell adhesion; delivering a second material to said vascular site to fill at least a portion of a volume of said vascular site; delivering a third material to said vascular site to protect said vascular site, whereby said second material fills said volume between said first material and said second material.
Parent Case Info
[0001] Applicant claims the right to priority under 35 U.S.C. §119(e) based on Provisional Patent Application No. 60/287,029 entitled “NOVEL METHOD AND APPARATUS FOR DELIVERING MATERIALS TO THE BODY,” filed Apr. 26, 2001, and which is expressly incorporated herein by reference in its entirety.
Provisional Applications (1)
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Number |
Date |
Country |
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60287029 |
Apr 2001 |
US |