Various embodiments concern acquisition of information indicating the condition of eyes, and/or the therapeutic relaxation of eyes. More particularly, various embodiments relate to determining pressures and/or stresses on the eyes, and/or opposing such pressures and/or stresses through adjusting the physical conditions of the eyes.
Stresses of various sorts in or on the eyes may be associated with certain medical conditions, and/or resultant symptoms of those conditions. For example, high intraocular pressure (sometimes abbreviated TOP) may be associated with glaucoma. While the intraocular pressure itself may or may not be the root cause of certain problems associated with glaucoma (e.g., progressive loss of vision), tracking intraocular pressure over time and/or acting to reduce intraocular pressure may avoid or reduce the severity of such problems. Similarly, physical damage to the optic nerve due to particular eye movements/positions may be associated with glaucoma, progressive deformation of the lens of the eye may be associated with extensive close-up focusing that applies long-term compressive stress to the lens, etc.
Approaches for determining such factors, e.g., intraocular pressure, stress to the optic nerve, compressive tension of the lens, etc., may depend on clinical equipment. For example, applanation tonometry may be utilized to measure intraocular pressure. Typically this may involve anesthetizing the eyes, applying a dye, and applying contact pressure to the eye to determine the amount of force necessary to flatten a portion of the cornea. The intraocular pressure then may be calculated from from that force. However, while such approaches may be effective they may not lend themselves to testing on a routine basis. For example, applanation tonometery may not be suitable for use by an individual patient who wishes to collect data daily, or at other specific intervals or times, in a non-clinical setting. If intraocular pressure monitoring is limited to a clinical setting, the intervals between data points may tend to be relatively long, e.g., weeks to months. Such monitoring may not reveal changes on shorter timescales, such as rapid increase or decrease, cyclical variation throughout the day, fluctuations due to particular activities, etc.
In addition, treatments for such stress-associated conditions, where treatments may exist at all, may depend on pharmaceutical intervention, and/or other interventions as may be considered aggressive (e.g., surgeries). Such treatments, while potentially effective, may present risks of side effects and/or other concerns.
This disclosure contemplates a variety of systems, apparatus, methods, and paradigms for determining various eye stresses, and/or for treating such eye stresses.
In one embodiment a method is provided that includes generating a base acoustic emission, acoustically communicating the base acoustic emission to a subject's eye, and acoustically receiving a return acoustic emission from the eye. The base acoustic emission and return acoustic emission are communicated to a processor, and are compared to identify an intraocular pressure descriptor for the eye. The processor then registers the intraocular pressure descriptor. The base acoustic emission may be communicated to the eye with a speaker of a head mounted display, the return acoustic emission may be received from the eye with a microphone of a head mounted display, and the processor may be in the head mounted display.
In another embodiment a method is provided that includes determining an intent eye configuration for a viewer, including the orientations of the left and right eyes, with that intent eye configuration corresponding with a reduction of the intraocular pressure of one or both eyes. The method includes determining an intent vergence depth for a visual target that corresponds with the intent eye configuration. Left and right stereo image fractions for the visual target are generated, and are displayed so as to enable resolution of the left and right stereo image fractions into the visual target by the viewer. The vergence depth of the left and right stereo image fractions is adjusted over time towards the intent vergence depth, such that responsive to resolving the left and right stereo image fractions the viewer's eyes are biased towards the intent eye configuration, so as to facilitate the reduction of intraocular pressure.
The method may include changing the vergence depth of the left and right stereo image fractions over time dynamically, proximate the intent vergence depth, such that in maintaining resolution of the left and right stereo image fractions by said viewer, the viewer's eyes are biased towards a dynamic eye configuration that is dynamically proximate the intent eye configuration. The method may include displaying the left and right stereo image fractions with a head mounted display, and changing the vergence depth of the left and right stereo image fractions with a processor of the head mounted display.
In another embodiment a method is provided that includes determining an intent eye configuration for a viewer's eyes that includes orientations of the left and right eyes, with the intent eye configuration corresponding to a reduction of intraocular pressure of. The method includes determining an intent vergence depth of a visual target corresponding with the intent eye configuration, determining an intent eye path of the visual target corresponding with the intent eye configuration, or both. Left and right stereo image fractions are generated for the visual target, and are displayed so as to enable a resolution of the left and right stereo image fractions by the viewer. The vergence depth of the left and right stereo image fractions may be changed over time towards the intent vergence depth, such that responsive to maintaining resolution of left and right stereo image fractions by the viewer the viewer's eyes are biased towards the intent eye configuration so as to facilitate reduction of the intraocular pressure; or the left and right stereo image fractions may be translated over time towards the intent eye path, such that responsive to maintaining resolution of left and right stereo image fractions by the viewer the viewer's eyes are biased toward the intent eye configuration so as to facilitate reduction of the intraocular pressure; or both.
The method may include changing the vergence depth of the left and right stereo image fractions over time dynamically about the intent vergence depth, such that responsive to maintaining resolution of left and right stereo image fractions the viewer's eyes are biased towards a dynamic eye configuration, that is dynamically proximate the intent eye configuration, so as to facilitate reduction of intraocular pressure. The method may include changing the target fraction path of the left and right stereo image fractions over time dynamically about the intent eye path, such that responsive to maintaining resolution of left and right stereo image fractions the viewer's eyes are biased towards a dynamic eye configuration, dynamically proximate the intent eye path, so as to facilitate reduction of intraocular pressure. The method may include displaying the left and right stereo image fractions with a head mounted display, and changing the vergence depth of the left and right stereo image fractions with a processor of said the mounted display, changing the target fraction path of the left and right stereo image fractions with the processor of the head mounted display, or both.
In another embodiment a method is provided that includes determining an intent eye configuration a viewer's eyes that includes the orientations of the eyes, wherein that intent eye configuration corresponds to the reduction of intraocular pressure. The method includes determining an intent vergence depth of a visual target corresponding with the intent eye configuration of said eyes, generating the visual target, displaying the visual target to the viewer, and translating the visual target such that responsive thereto the viewer's eyes bias towards the intent eye configuration so as to facilitate reduction of intraocular pressure. The method may include displaying the left and right stereo image fractions with a head mounted display, and translating the visual target with a processor of the head mounted display.
In another embodiment a method is provided that includes determining an intent eye configuration a viewer that includes an intent focus depth of the lenses of the viewer's eyes, with the intent eye configuration corresponding to a decrease in myopia. The method includes determining an intent focus depth of a visual target corresponding with the intent eye configuration, and determining the intent vergence depth of the visual target that corresponds with the intent focus depth. Left and right stereo image fractions are generated for the visual target, and are displayed with a vergence depth thereto so as to enable resolution of left and right stereo image fractions by the viewer. The vergence depth of the left and right stereo image fractions is changed over time towards the intent vergence depth, such that responsive to maintaining resolution of left and right stereo image fractions the viewer's eyes are biased towards the intent eye configuration, so as to facilitate the decrease in myopia.
The method may include determining an intent eye path of the visual target corresponding with the intent eye configuration, and determining an intent target path of the visual target corresponding with said intent eye path. The method may include displaying the left and right stereo image fractions with a target fraction position to enable resolution of left and right stereo image fractions by the viewer. The method may include changing the target fraction position of the left and right stereo image fractions over time towards the intent target path, such that responsive to maintaining resolution of the left and right stereo image fractions the viewer's eyes are biased towards the intent eye configuration, so as to facilitate a decrease in myopia.
The method may include displaying the left and right stereo image fractions with a head mounted display, changing the vergence depth of the left and right stereo image fractions with a processor of the head mounted display.
In another embodiment a method is provided that includes determining an intent eye configuration that corresponds to an intent test path for said eyes, determining an intent target path of a visual target corresponding with the intent eye configuration, and determining left and right intent display positions for left and right stereo image fractions for the visual target that correspond with with the intent eye configuration. Left and right stereo image fractions are generated for the visual target, and are displayed at display positions to enable resolution of the left and right stereo image fractions by the viewer. The display positions of the left and right stereo image fractions are changed over time towards the intent display positions, such that responsive to maintaining resolution of the left and right stereo image fractions the viewer's eyes are biased towards the intent eye configuration, so as to facilitate executing a test of said eyes. The method includes executing the test, and registering the test.
In another embodiment a method is provided that includes determining a first intent eye configuration for a viewer that includes a first intent eye configuration, corresponding to an intent test path for the eyes. The method includes determining a first intent target path of a first visual target corresponding with the first intent eye configuration, and determining first left and right intent display positions for first left and right stereo image fractions for the first visual target corresponding with the first intent eye configuration. The first first left and right stereo image fractions are generated for the first visual target and are displayed at first display positions so as to enable resolution of the first left and right stereo image fractions by the viewer. The method includes changing the first display positions of the first left and right stereo image fractions over time towards the first intent display positions, such that responsive to maintaining resolution of first left and right stereo image fractions the viewer's eyes are biased towards the first intent eye configuration so as to facilitate executing an acoustic test of said eyes.
The method includes generating a base acoustic emission, acoustically communicating the base acoustic emission to one of the eyes of the viewer, and acoustically receiving a return acoustic emission from the eye. The method includes comparing the base acoustic emission and the return acoustic emission so as to identify an intraocular pressure descriptor for the eye. The intraocular pressure descriptor is registered.
The method includes determining a second intent eye configuration for that includes second orientations of the left and right eyes, wherein the second intent eye configuration corresponds to reduction of intraocular pressure. The method includes determining a second intent vergence depth of a second visual target corresponding with the second intent eye configuration, determining a second intent eye path of the second visual target corresponding with the second intent eye configuration, or both. Left and right stereo image fractions are generated for the second visual target, and are displayed so as to enable resolution of the second left and right stereo image fractions by the viewer. The method includes changing the second vergence depth of the second left and right stereo image fractions over time towards the second intent vergence depth, such that responsive to maintaining resolution of second left and right stereo image fractions the viewer's eyes bias towards the second intent eye configuration, so as to facilitate reduction of intraocular pressure; or translating the second left and right stereo image fractions over time towards the second intent eye path, such that responsive to maintaining resolution of second left and right stereo image fractions the viewer's eyes bias toward the second intent eye configuration, so as to facilitate reduction of intraocular pressure; or both.
Various objects, features, and characteristics will become more apparent to those skilled in the art from a study of the following Detailed Description in conjunction with the appended claims and drawings, all of which form a part of this specification. While the accompanying drawings include illustrations of various embodiments, the drawings are not intended to limit the claimed subject matter.
The figures depict various embodiments described throughout the Detailed Description for the purposes of illustration only. While specific embodiments have been shown by way of example in the drawings and are described in detail below, the technology is amenable to various modifications and alternative forms. The intention is not to limit the technology to the particular embodiments described. Accordingly, the claimed subject matter is intended to cover all modifications, equivalents, and alternatives falling within the scope of the technology as defined by the appended claims.
The figures depict various embodiments described throughout the Detailed Description for the purposes of illustration only. While specific embodiments have been shown by way of example in the drawings and are described in detail below, the technology is amenable to various modifications and alternative forms. The intention is not to limit the technology to the particular embodiments described. Accordingly, the claimed subject matter is intended to cover all modifications, equivalents, and alternatives falling within the scope of the technology as defined by the appended claims.
As an initial and non-limiting summary, certain approaches are presented as examples herein.
With regard to evaluations, intraocular pressure may be determined acoustically, by sending an acoustic base signal towards an eye (without necessarily making physical contact between the emitter and the eye), and monitoring an acoustic return from the eye (again without necessarily making physical contact between the eye and the receiver). Comparison of the base and return signals may provide an indication of the intraocular pressure. For example, considering the eye as a fluid-filled sphere, the internal pressure, surface tension, etc. may affect the transformation (if any) of an acoustic emission that is sent towards the eye. In colloquial terms, the process may be considered as a form of sonar. Regardless of whether intraocular pressure is in itself a cause of damage associated with glaucoma or a symptom of glaucoma, variations in intraocular pressure may be revealing as to the current state and/or progress of glaucoma.
With regard to therapeutic intervention, disposing eyes in a “rest” or “neutral” configuration may address various stresses on the eyes. For example, certain eye orientations, eye motions, etc. may be associated with the application of physical stresses on the optic nerve and/or other eye structures; those stresses in turn may be associated with glaucoma and vision loss therefrom. In orienting the eyes in a neutral position, where such stresses may be to at least some extent avoided, damage to the eyes may be reduced or even counteracted. In colloquial terms, the eye may be allowed to rest for a time, and that rest may help to avoid or even reverse vision loss. For illustrative purposes, an analogy may be drawn to placing wrists in a neutral for some period to counteract carpal tunnel syndrome (though it is not suggested that the comparison is exact); providing the relevant physical structures with an opportunity to rest, even briefly, may be useful.
Somewhat similarly thereto, as another example tension in the muscles that orient the eyes may apply compression to the eyes, thus potentially increasing intraocular pressure which may in turn contribute to eye damage and loss of vision from glaucoma. In orienting the eyes to a neutral position, the muscles that orient the eyes may be encouraged to relax, again providing what might be colloquially referred to as a rest. Such relaxation may oppose elevated intraocular pressure, etc.
As another example, the muscles used to distort the lens of the eye so as to vary the focus thereof may cause permanent deformation of the lens, permanent shortening of the focusing muscles, and/or similar. Whether due to the lens becoming biased towards a particular focus (e.g., close up focusing), the muscles becoming incapable of fully relaxing, etc., the ability of the eye to focus throughout its full nominal range may become restricted. More concretely, if the eye is biased towards a focus on close objects, the eye's capability to focus on distant objects may be diminished (e.g., the eye may be said to be myopic). Again, by reconfiguring the eyes towards a different state—to continue the example above, encouraging the focusing muscles to act as though focusing on a distant target—myopia and/or other conditions may be opposed or even reversed. (It is noted that while a relatively straightforward presentation is made for a potential problem as may be addressed, in practice eye focus and/or other eye concerns may be more complex than is described herein for purposes of example. For instance, eye focus may involve not only the contraction of the ciliary muscle but also the suspensory ligaments, and/or other factors. A comprehensive structural and/or medical analysis of the eye is not presented herein.)
So as to achieve such eye relaxation, the eyes may be encouraged to act as though focusing on distant objects by presenting visual targets that exhibit a vergence associated with large distance, e.g., “at infinity” in a visual sense. Presenting suitable targets with suitable vergence may be accomplished conveniently through the use of a stereo display, such as a head mounted display (HMD). While real-world distance might at least in principle be utilized, presenting specific distances, specific variations in distance, specific positions within the visual field, etc. may not be practical when the real-world distance associated with a particular vergence is greater than may be achieved within a given room. Artificial visual targets with well-controlled vergence may exhibit advantages in therapeutic applications. In more colloquial terms, a head mounted display (such as a virtual reality headset, an augmented reality headset, etc.) may present a target that appears in terms of vergence to be at a distance of (for example) 6 meters even if the viewer is inside an office cube, room, or other enclosed space where no wall is more than 2 meters away, may present that target so as to appear to oscillate between (for example) 3.5 and 4.5 meters away, etc.
It is emphasized that the therapeutic techniques under consideration may be used relatively briefly; it is not required that relaxation therapy for eye motion, eye orienting muscle tension, eye focusing muscle tension, etc. must be, or even necessarily could be, carried out continuously. Rather, rest periods with reduced or at least differing stresses may be therapeutically useful.
The orientation of the acoustic emitter 0112 and acoustic receiver 0114 are not limited. Moreover, while the acoustic emitter 0112 and acoustic receiver 0114 are shown for simplicity as being two distinct components, in other arrangements it may be suitable for a single element to function both to send and to receive acoustic emissions. Further, while only two elements of a test system 0110 are shown, the test system 0110 is not limited only thereto. For example, a test system 0110 may include a processor, other instruments, a display, etc. As a more concrete example, a test system 0110 may be or include a smart phone or similar device, e.g., with a speaker as may function as an acoustic emitter, a microphone as may function as an acoustic receiver, an on-board processor, etc. As another example, a smart phone or similar may function as part of a test system 0110, with other elements also being part of the test system 0110, e.g., a dedicated “plug in” acoustic emitter 0112 and/or a dedicated “plug in” acoustic receiver 0114. Other arrangements also may be suitable.
Turning to
Now with reference to
Typically though not necessarily, the return acoustic emission 0118 as shown in
Notably however, certain transformations as may manifest between a given base acoustic emission 0116 and a resulting return acoustic emission 0118 may carry information regarding physical properties of the eye 0102. For example, given an eye of at least approximately known dimensions and configuration (e.g., a “typical” human eye), the intraocular pressure—the pressure of fluid therein—may affect the manner and degree of transformation between the base acoustic emission 0116 and the return acoustic emission 0118. For example, the physical tension of the surface of the eye 0102 may be at least in part a function of the internal fluid pressure within the eye 0102, e.g., higher internal fluid pressure may produce greater tension of the surface. As may be understood, the tension of a membrane such as a drum head may at least partially determine the pitch of sound produced when that membrane is struck; similarly the tension of the structure of the eye 0102 may impact the return acoustic emission 0118.
For example, if a return acoustic emission 0118 were to be shifted in pitch from a base acoustic emission 0116, that shift may be at least in part a function of the tension on the eye 0102, and thus may be a function of the intraocular pressure of that eye 0102. This is an example only; the potential variations in modification of a base acoustic emission 0116 in yielding a return acoustic emission 0118 may vary greatly, depending at least in part on the particulars of the base acoustic emission 0116 as well as on the particulars of the eye 0102 in question. As another example, some portion of the base acoustic emission 0116 may be conducted around the eye along the tensioned surface thereof, with the speed of such conduction being a function of the tension; in such case a lag time between emission of the base acoustic emission 0116 and the return of that portion of the return acoustic emission 0118 may be indicative of the tension of the eye surface, and/or thus indicative of the intraocular pressure of the eye 0102.
As yet another example, a resonant frequency of the eye may be at least in part a function of the intraocular pressure therein. Thus, varying the frequency of the base acoustic emission 0116 to find a point at which the return acoustic emission 0118 is consistent with the eye 0102 being addressed at a resonant frequency may be suitable. As a related note, while in
It is noted that a lack of change also may be considered. For example, if a base acoustic emission 0116 does not exhibit some particular change in a return acoustic emission 0118 for intraocular pressures above some threshold value, then observing that the return acoustic emission 0118 is not different in that respect from the base acoustic emission 0116 also may be relevant. Thus, a lack of change may be considered as well as a presence of change.
Other arrangements also may be considered, so long as in comparing the base acoustic emission 0116 and the return acoustic emission 0118 some descriptor of the intraocular pressure may be determined therefrom. It is noted that a “descriptor” of intraocular pressure as the term is used herein does not necessarily imply a measurement of intraocular pressure. For example, if a given comparison of a base acoustic emission 0116 and a return acoustic emission 0118 were to reveal that intraocular pressure were rising or falling, such an arrangement may be sufficient. Even an arrangement that reveals only that intraocular pressure is either remaining stable or not, without even indicating a direction of change, may be of use. While accurate and/or precise measurements of intraocular pressure are not excluded, so long as some therapeutically useful information may be discerned therefrom, the nature of the descriptor is not limited.
As a more concrete example, it may be suitable for a descriptor to be a simple numerical value, such as “6”. The value itself may not represent a measure of intraocular pressure; it may not be 6 “of anything”, just 6. However, if an increase of that value to 9 (for example) may indicate a change in intraocular pressure (whether an increase, a decrease, or even a change in unknown direction), then such a numerical value may be suitable as a descriptor for purposes herein.
In addition, with regard collectively to
Moving on to
Continuing in
Though not shown in
Continuing in
The base acoustic emission and return acoustic emission are compared 0230 in the processor. The precise nature of the comparison may depend at least in part on the particulars of the acoustic emissions, the anticipated difference(s) between the base and return acoustic emissions, etc. Typically though not necessarily some algorithm may be used to identify features of the return acoustic emission as differ from the base acoustic emission, and/or to correlate such differences, etc.
An intraocular pressure descriptor is determined 0232 from the comparison 0230 of the base and return acoustic emissions in the processor. As noted previously herein, the descriptor may be a measurement of intraocular pressure, and/or may be some non-measurement indication that intraocular pressure has or has not changed, has risen or fallen, etc. Thus the descriptor may be a pressure value, but alternately or in addition may include other information.
Still with reference to
Now with reference to
As may be seen, the eyes 302A and 302B are angled inward towards one another; this angling may be referred to as vergence. The vergence that a viewer must exhibit in order to resolve the visual inputs from their left and right eyes 0302A and 0303B is a function of the distance to whatever target the user is attempting to resolve. Thus, the amount of vergence may used by the brain as an indication of the distance to the target in question, and may be useful in depth perception. Typically such distance may be carried out at an unconscious level. In presenting target fractions 0350A and 0350B in appropriate positions on displays 0344A and 0344B in a stereo configuration, an appearance of depth may be produced for a virtual target 0352 that is much greater than the physical distance to the displays 0344A and 0344B.
Now with reference to
Turning to
As may be understood through a comparison of
In practice, human eyes do not function in a geometrically perfect or absolute manner, and thus the arrangements in
In addition, it is noted that presenting target fractions 0350A and 0350B as shown does not necessarily control eye position, per se. The user may consciously choose to track such target fractions 0350A and 0350B or not. Thus, no absolute link is proposed; presenting and/or moving target fractions 0350A and 0350B to a user does not compel that user to track those target fractions 0350A and 0350B or to adjust the orientation of the user's eyes 0302A and 0302B. However, the human visual system is such that targets may be made naturally eye-catching, e.g., by moving or animating target fractions 0350A and 0350B, by displaying target fractions 0350A and 0350B prominently against a blank, uniform, or otherwise visually uninteresting background, by changing the apparent depth of the combined virtual target 0352, etc. Thus a useful degree of bias may be provided to encourage a user to track the content of interest, so as to reorient the user's eyes 0302A and 0302B in a therapeutically positive manner. Such encouragement may not even be apparent to the user on a conscious level, e.g., humans tend to track moving objects reflexively. Given suitable content suitably presented, the reorientation of the user's eyes 0302A and 0302B may require little or no effort or positive action on the part of a user, aside from the choice to make use of the approach in the first place. In colloquial terms, the eyes may be said to behave automatically when presented with appropriate content.
It is noted that for explanatory purposes,
Related to such variations, particularly to vertical and/or horizontal motion within the user's field of view, it will be understood that the orientation of each eye 0302A and 0302B may be biased independently of one another to at least some degree. That is, with a virtual target 0352 centered in the field of view the inward vergence of each eye may be anticipated to be at least approximately equal in magnitude (though opposite in direction). However, for a virtual target to the left of center the right eye 0302B typically would be oriented leftward to a greater degree than would the left eye 0302A, and vice versa. Since human eyes typically tend to work together in a coordinated manner (e.g., to align both eyes with a target of interest) it may not be possible (or even necessarily desirable) to orient a user's eyes in a completely independent fashion. However, some degree of difference in orientation between left and right eyes 0302A and 0302B may be encouraged through suitable placement of target fractions 0350A and 0350B. In addition, to at least some degree such independence of orientation may be facilitated by blanking one or the other of the displays 0344A and 0344B so that the corresponding eye receives no input and thus has nothing on which to focus.
Thus with respect to
What precisely may constitute desirable and/or undesirable orientations and/or motions of human eyes in a therapeutic sense may vary. For example, certain orientations and/or motions of the eyes may cause, aggravate, or at least contribute to certain eye health concerns. As a more concrete example, the optic nerve and associated structures are disposed generally at the back of the eye. Certain positions, motions, and/or speeds of motions may apply static and/or dynamic physical stresses to the optic nerve. While individually such stresses may appear insignificant, with repetition such stresses may prove to be problematic. Damage to the optic nerve may occur in a process at least somewhat analogous with repetitive stress injuries such as carpal tunnel syndrome, e.g., any single motion or position may be innocuous but sufficient repetition over time without rest or therapy may result in significant, potentially lasting harm. There is at least some reason to suspect that at least some cases of glaucoma may be driven not by excessive intraocular pressure, or at least not by intraocular pressure alone, but by ongoing mechanical stress to the optic nerve. For example, such a cause may explain cases wherein the visual degradation typical of glaucoma may be present but intraocular pressure appears normal. Thus, therapy to avoid harmful orientations and/or motions, and/or to encourage beneficial orientations and/or motions, may be of use in addressing glaucoma in at least certain patients.
As another example, eye orientation is controlled by a series of muscles attached to the eye and the surrounding tissue. Contraction of such muscles causes the eyes to shift their orientation up, down, left, right, etc. However, as in other muscles in the human body, the contraction of one muscle does not inherently cause an opposing muscle to fully relax. Various body muscles may retain some degree of tension, even when not actively reorienting the structures to which those muscles are attached. This may be true of muscles that control eye orientation as well, in at least some cases. Thus, one, several, or all muscles responsible for eye orientation may be at least somewhat in tension even when the eye is nominally stationary. Such tension in the eye muscles may increase or at least contribute to the increase of the intraocular pressure, e.g., tension in muscles connected to the eye applies mechanical compression to the eye, increasing the pressure therein. (The effect may be at least somewhat analogous to squeezing a water filled balloon, though the structures and forces are not necessarily identical.) Given that increased intraocular pressure may be associated with glaucoma, the potential may exist for tension in the muscles controlling eye orientation to aggravate, contribute to, and/or cause glaucoma in at least some patients. Conversely, reducing tension in the muscles controlling eye orientation may be therapeutically useful in addressing glaucoma, in at least such patients. It is noted that in at least certain eye surgeries, temporarily severing certain muscles controlling the eye may reduce the intraocular pressure; in effect, removing (or at least reducing) the applied tension may reduce the internal pressure.
As another example regarding potential desirable and/or undesirable eye orientations and motions, the focal depth of the eye is adjusted by muscles surrounding the lens that, when contracted, change the shape of the lens. The orientation of the eye does not absolutely control the contraction of the lens shaping muscles. However, given a target at a certain apparent depth, there is a natural tendency to focus the eye to that depth. Thus, given stereo targets displayed at a suitable depth, a bias may be applied to the lens shaping muscles. For example, a virtual target is presented at a given apparent depth, the eye orienting muscles orient the eyes orient to a vergence suitable for that depth, and the lens shaping muscles act in coordination with the eye orienting muscles to shape the lens to a suitable form for focusing on an object at that depth. However, certain behaviors may cause potentially lasting changes to the eye, that may reduce the eye's ability to focus across a full range of depths. When a person looks at a close target, the eye shaping muscles contract strongly to deform the lens to exhibit a short focal length. If a person looks at close targets for long periods, the eye shaping muscles may develop a bias towards compression, potentially becoming less capable of fully relaxing (and thus of enabling focus on distant objects). Likewise, the lens itself may undergo a degree of lasting deformation, potentially becoming less capable of returning to a shape suited for focus on distant objects. In either case, distance vision may suffer.
It is noted that certain practices that are currently common may contribute towards issues referenced in the preceding examples. For example, use of a smart phone or similar device, wherein the screen is held close to the eyes, may require a high degree of vergence of the eyes and/or a high degree of compression of the eye lens by the lens shaping muscles. Similarly, the use of computer monitors also may require a high degree of vergence and/or lens compression (though perhaps not such a high degree as with a smart phone). In both cases, it may be common for large numbers of persons to use such devices for long periods of time, e.g., tying on a laptop computer for hours at a time, texting on a smart phone for hours, etc. While a certain and absolute causative link between such practices and various eye health conditions is not proposed herein, and is not required, the potential risks may be non-trivial in scope and/or severity.
As noted previously, typically muscle actions associated with vision, and coordination therebetween, may be unconscious, e.g., positive action may not be required on the part of a viewer to make the orienting muscles in their left and right eyes to coordinate so that both eyes exhibit suitable vergence for a target at a given depth, or to make lens shaping muscles contract, relax, etc. However, that very unconscious nature of such actions may in at least certain cases present difficulties. A muscle that does not require conscious control may in at least certain circumstances be resistant to conscious control. Deliberately selecting a specific configuration and/or degree of tension in the eye orienting muscles, lens shaping muscles, etc. may prove difficult for at least many patients. As a more concrete example, it may be challenging to align and/or focus the eyes to “infinity” when in a confined space such as an office cubicle or a small apartment room, wherein every object within the visual field is much closer than infinity, e.g., a few meters away or less.
Thus, while in the abstract it may be a simple matter of relaxing the appropriate muscles to avoid potential eye health issues, in practice “just relax” may be of limited usefulness without some supporting therapy. Likewise, in principle pharmaceutical agents exist that may assist in relaxing certain eye related muscles and/or other tissues, e.g., belladonna and/or extracts thereof may be used for such applications. However, the long term, regular use of such pharmaceutical agents may not be well understood, and even when well understood may present risks of significant side effects. (For example, belladonna may be toxic in certain doses, and the effects of routine use over long periods may not be well documented medically.)
However, to return to the arrangements in
Typically though not necessarily, therapy as considered herein may be at least broadly understood as opposing the factors as may be causing the difficulties. For mechanical-interference issues with the optic nerve bundle, therapy may include but is not limited to providing periods of reduced mechanical stress by orienting and/or moving the eyes in a manner that does not contribute to such mechanical interference and/or associated damage. For eye orienting muscle tension as may contribute to increased intraocular pressure, therapy may include but is not limited to relaxing tension in the relevant muscles by orienting the eyes in a “neutral” position as may facilitate low stress in and/or relaxation of those muscles. For lens compression as may contribute to myopia, therapy may include but is not limited to relaxing contraction of the lens shaping muscles so as to relieve tension therein and/or reduce applied forces to the lens, e.g., through presenting visual content at apparent (vergence based) distances that would correspond with a long focus of the eye lens. In certain cases therapy may include or be a form of training, e.g., leading a user in practicing non-damaging eye motions with regard to mechanical stress on the optic nerve, so as to encourage the user in making such motions habitual. However, these are examples only, and other arrangements also may be suitable.
In addition, it is noted that the precise conditions, orientations, motions, etc. may vary due to a number of factors, including the specific user, their particular medical concerns, etc., and are not limited herein. Likewise, the degree of benefit (if any) from a given therapeutic visual program may vary as well, and also are not limited herein. Similarly, the degree of efficacy, the duration of effect, the frequency and duration of therapy sessions, etc. may depend on a wide range of variables, and are not limited herein.
Turning now to
An arrangement as shown in
Moving on to
As may be seen, in
Now with reference to
Thus together,
Turning to
In
Display positions for left and right stereo target fractions are determined 0678 so as to be consistent with the intent eye orientation determination 0676 as described above. Given a particular configuration of the patient's eyes, where should target fractions be displayed to the patient viewing those target fractions in order to achieve or at least approach the intent eye orientation? Alternately, the matter might be considered as: what apparent depth should the target exhibit, and where in the viewer's visual fields should target fractions be presented to achieve that apparent depth? The target fraction display positions may vary from one patient to another just as may the intent eye orientation. In addition, other factors including but not limited to the particulars of the mechanism that will display the target fractions, e.g., different designs of head mounted displays may have screens of different sizes, at different distances, etc., and a system making use of a computer monitor may exhibit different optical geometries than a head mounted display, etc.
In colloquial and non-limiting terms, steps 0676 and 0678 may be understood as determining “what should the eyes do?” and “where should the content be placed to encourage the eyes do that?” Either or both determination may be applicable to multiple types of content, e.g., positioning a virtual fish or dolphin swimming in a virtual sea may be similar to positioning a virtual dragonfly flitting through a virtual forest, or a virtual aircraft in a virtual sky. The type, form, etc. of the target is not limited. Targets may be photorealistic, illustrative, or abstract, may be animated or static, color, grayscale, or black and white, may be of varying sizes and/or resolutions, etc. In addition, while certain examples herein may refer to targets presenting as real world elements, such as a fish, a dolphin, etc., other targets including but not limited to emojis, letters or numbers, etc. also may be suitable.
As a related matter, while only target content (what the viewer is supposed to look at to achieve therapeutic effects) is specifically addressed within
Continuing in
The left and right stereo target fractions are displayed 0682 to the viewer's left and right visual fields, respectively. For example, considering an arrangement such as that shown previously in
It is noted that, while target fraction display positions may have been determined 0678 already, it is not required that the target fractions be immediately displayed in the target fraction display positions (though this also is not prohibited). Rather, the target fractions may be adjusted 0684 towards the target fraction display positions, e.g., being first displayed 0682 in convenient and/or comfortable positions for the viewer and then being adjusted 0684 towards (and typically though not necessarily to) the desired target fraction display positions. In at least certain instances it may be uncomfortable or undesirable to immediately require the viewer to resolve a stereo target at an apparent depth, position, etc. as may be therapeutically useful; thus, the viewer may be “eased in” to, or at least towards, the desired eye configuration.
Similarly, while the target fractions may be maintained in therapeutically useful positions for some period of time (as may vary with the medical condition in question, the patient, etc.), it is not necessarily required that the target fractions be held precisely at the target fraction display positions at all times during therapy. Indeed, it may be useful in at least some cases to deliberately vary the apparent depth, position, etc. of the target being displayed. For example, with regard to the specific example of glaucoma related to eye orienting muscle tension in
While the arrangement in
Now with reference to
Beginning in
As noted not all methods necessarily will have all steps; for example depending on the particulars of execution, steps such as diagnosis may be considered, even though diagnosis is not explicitly shown in
Continuing in
An intent eye behavior profile is established 0776. The eye behaviors as may be included in carrying out a given therapeutic regimen and/or to reach a given therapeutic goal are defined, determined algorithmically, or through some other approach. For example, the eyes must be brought to center, then gradually moved to neutral orientation, then cycled slowly into and out of that neutral orientation, then put through pan and tilt motions, etc. Step 0676 of
Still in
While intent target behavior profiles may be tailored, individually generated for a given patient/condition, produced algorithmically in real time, etc., it may also be suitable for a given intent target behavior profile to be predetermined. For example, it may be that one or several “general purpose” presentations of a visual target may be suited for many or even all patients. Such general purpose presentations may be prepared in advance, e.g., being prerecorded and stored in processor memory, etc. Similarly, certain aspects may be predetermined while others are created in real time, for example a set of target motions may be prerecorded, while the target itself is selected or customized by a user, randomly generated, etc. (or vice versa). (It is noted that if an intent target behavior profile were prerecorded and widely used, such prerecording may occur well in advance of certain other steps that are numerically presented ahead of step 0778 in
Continuing in
The left and right stereo target fractions are displayed 0782, typically though not necessarily to left and right respective visual fields within a display (though presentation on two separate displays or other options also may be suitable), such that a viewer may view the left stereo target fraction with the left eye and the right stereo target fraction with the right eye, and so resolve the fractions as a combined target with an apparent depth. As noted with regard to
Continuing in
The intent target behavior profile is executed 0786 with the stereo target fractions. Thus, at least nominally, the stereo target fractions follow the “flight plan” of the intent target behavior profile. However, even once following the intent target behavior profile, deviation therefrom may be suitable; should it be found that the viewer is not visually tracking the target, the stereo target fractions may be adjusted off-profile should such action be useful in addressing the matter (e.g., making it easier for the viewer to track the target, attracting the viewer's attention, etc.). A detailed if-then loop for such adjustments is not explicitly presented herein.
Continuing in
As an aside, it is noted that, should eye tracking be performed, tracking eye behavior 0788 may be an ongoing process. Tracking thus may take place in parallel with certain other steps, e.g., in coordination with executing 0786 the intent target behavior profile. As noted, ordering of methods is not necessarily fixed to the specific arrangement illustrated for
Should eye tracking or other compliance data be obtained as part of the method (or is otherwise available), the compliance of the viewer's eye behavior may be evaluated 0790 against the intent eye behavior profile. Such evaluation may address the matter of whether the viewer's eyes moved and/or otherwise behaved as intended for the therapeutic session. Evaluation may vary in form and/or complexity. For example, a simple “fair/poor/good” standard may be utilized, an accuracy percentage may be determined, detailed information about how, when, and/or where the viewer's eyes did not move as anticipated/desired, etc.
Moving now to
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The term “establishing” various elements as used herein should be understood broadly. In establishing an image, standard, regimen, motion path, etc., such elements may be loaded into a processor from stored executable instructions, may be defined as rule sets, may be calculated based on data and/or instructions, may be the result of the professional judgment of a medical professional, may be selected by the user, etc. It is noted that such options are not necessarily exclusive, and a given embodiment may utilize more than one. The manner by which features referenced herein may be established is not limited.
Now with reference to
In
Continuing in
Left and right stereo target fractions are established 0880. The left and right stereo target fractions are displayed 0882 per the intent target behavior profile. Certain previous examples have noted that a visual target may be presented first elsewhere, e.g., in a convenient position/configuration and then adjusted towards the intent target behavior profile. However, as also noted, it may be suitable to display 0882 the target fractions at or at least approximately at the location(s) specified by the intent target behavior profile, without first being positioned “off plan” and then being adjusted. The arrangement in
The intent target behavior profile is executed 0886 with the stereo target fractions. To continue the simple example wherein the viewer is desired to look straight ahead, in such case executing 0886 the intent target behavior profile may include holding a suitable position for some predetermined length of time, until some action completes, until data is fully acquired, until the viewer or some other person gives a command, etc. However, the intent target behavior profile is not limited to such, and other (potentially much more complex) movements, positions, transformations, etc. for the stereo target fractions may be executed 0886.
An eye parameter is determined 0888. For example, a determination regarding (e.g., a measurement of) intraocular pressure may be made, an image of the eye may be taken, etc. As previously noted with regard to
Still with reference to
Now with reference to
In
Continuing in
It is noted that a variety of eye related therapeutic processes, apparatuses, etc. are presented herein as examples. While certain such are presented individually for purposes of clarity, combination thereof also may be suitable. For example, an arrangement as may be similar to that in
In addition, it is noted that some or all such processes and/or sub-processes may be carried out in an automated manner. For example, test preparation, testing, and/or treatment may be implemented through processor control, e.g., the activation of executable instructions instantiated on a processor. Systems likewise may be adaptive, responding to the user's performance, for example modifying, extending, reducing, adding, and/or removing functions based on test results, eye tracking, degree of adherence to a treatment regimen, etc. As a more concrete example, a system may respond to progression of glaucoma in a patient may respond by changing to a treatment regimen (e.g., eye focus, eye movement, etc.) that is more intensive, increasing treatment session length and/or frequency, or advising the patient to contact an eye care professional (or contact such a professional automatically). In addition, systems may interact more directly with patients, such as by monitoring for keywords or key phrases (“pressure in my eyes”), accepting commands through voice input or other avenues, etc. Any or all such functions may be carried out autonomously, without the need for direct routine involvement by eye care professionals. While involvement of an eye care professional or other caregiver is not excluded, neither may such involvement be required.
Now with reference to
In various embodiments, the processing system 1000 operates as a standalone device, although the processing system 1000 may be connected (e.g., wired or wirelessly) to other machines. In a networked deployment, the processing system 1000 may operate in the capacity of a server or a client machine in a client-server network environment, or as a peer machine in a peer-to-peer (or distributed) network environment.
The processing system 1000 may be a server, a personal computer (PC), a tablet computer, a laptop computer, a personal digital assistant (PDA), a mobile phone, a processor, a telephone, a web appliance, a network router, switch or bridge, a console, a hand-held console, a (hand-held) gaming device, a music player, any portable, mobile, hand-held device, or any machine capable of executing a set of instructions (sequential or otherwise) that specify actions to be taken by the processing system.
While the main memory 1006, non-volatile memory 1010, and storage medium 1026 (also called a “machine-readable medium) are shown to be a single medium, the term “machine-readable medium” and “storage medium” should be taken to include a single medium or multiple media (e.g., a centralized or distributed database, and/or associated caches and servers) that store one or more sets of instructions 1028. The term “machine-readable medium” and “storage medium” shall also be taken to include any medium that is capable of storing, encoding, or carrying a set of instructions for execution by the processing system and that cause the processing system to perform any one or more of the methodologies of the presently disclosed embodiments.
Still with reference to
Moreover, while embodiments have been described in the context of fully functioning computers and computer systems, those skilled in the art will appreciate that the various embodiments are capable of being distributed as a program product in a variety of forms, and that the disclosure applies equally regardless of the particular type of machine or computer-readable media used to actually effect the distribution.
Further examples of machine-readable storage media, machine-readable media, or computer-readable (storage) media include, but are not limited to, recordable type media such as volatile and non-volatile memory devices 1010, floppy and other removable disks, hard disk drives, optical disks (e.g., Compact Disk Read-Only Memory (CD ROMS), Digital Versatile Disks, (DVDs)), and transmission type media such as digital and analog communication links.
The network adapter 1012 enables the processing system 1000 to mediate data in a network 1014 with an entity that is external to the computing device 1000, through any known and/or convenient communications protocol supported by the processing system 1000 and the external entity. The network adapter 1012 can include one or more of a network adapter card, a wireless network interface card, a router, an access point, a wireless router, a switch, a multilayer switch, a protocol converter, a gateway, a bridge, bridge router, a hub, a digital media receiver, and/or a repeater.
The network adapter 1012 can include a firewall that can, in some embodiments, govern and/or manage permission to access/proxy data in a computer network, and track varying levels of trust between different machines and/or applications. The firewall can be any number of modules having any combination of hardware and/or software components able to enforce a predetermined set of access rights between a particular set of machines and applications, machines and machines, and/or applications and applications, for example, to regulate the flow of traffic and resource sharing between these varying entities. The firewall may additionally manage and/or have access to an access control list which details permissions including for example, the access and operation rights of an object by an individual, a machine, and/or an application, and the circumstances under which the permission rights stand.
As indicated above, the computer-implemented systems introduced here can be implemented by hardware (e.g., programmable circuitry such as microprocessors), software, firmware, or a combination of such forms. For example, some computer-implemented systems may be embodied entirely in special-purpose hardwired (i.e., non-programmable) circuitry. Special-purpose circuitry can be in the form of, for example, application-specific integrated circuits (ASICs), programmable logic devices (PLDs), field-programmable gate arrays (FPGAs), etc.
The foregoing description of various embodiments of the claimed subject matter has been provided for the purposes of illustration and description. It is not intended to be exhaustive or to limit the claimed subject matter to the precise forms disclosed. Many modifications and variations will be apparent to one skilled in the art. Embodiments were chosen and described in order to best describe the principles of the invention and its practical applications, thereby enabling others skilled in the relevant art to understand the claimed subject matter, the various embodiments, and the various modifications that are suited to the particular uses contemplated.
While embodiments have been described in the context of fully functioning computers and computer systems, those skilled in the art will appreciate that the various embodiments are capable of being distributed as a program product in a variety of forms, and that the disclosure applies equally regardless of the particular type of machine or computer-readable media used to actually effect the distribution.
Although the above Detailed Description describes certain embodiments and the best mode contemplated, no matter how detailed the above appears in text, the embodiments can be practiced in many ways. Details of the systems and methods may vary considerably in their implementation details, while still being encompassed by the specification. As noted above, particular terminology used when describing certain features or aspects of various embodiments should not be taken to imply that the terminology is being redefined herein to be restricted to any specific characteristics, features, or aspects of the invention with which that terminology is associated. In general, the terms used in the following claims should not be construed to limit the invention to the specific embodiments disclosed in the specification, unless those terms are explicitly defined herein. Accordingly, the actual scope of the invention encompasses not only the disclosed embodiments, but also all equivalent ways of practicing or implementing the embodiments under the claims.
The language used in the specification has been principally selected for readability and instructional purposes, and it may not have been selected to delineate or circumscribe the inventive subject matter. It is therefore intended that the scope of the invention be limited not by this Detailed Description, but rather by any claims that issue on an application based hereon. Accordingly, the disclosure of various embodiments is intended to be illustrative, but not limiting, of the scope of the embodiments, which is set forth in the following claims.
This application claims the benefit of U.S. Provisional Application Ser. No. 63/201,052 filed on Apr. 9, 2021, the contents of which are incorporated by reference for all intents and purposes.
Number | Date | Country | |
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63201052 | Apr 2021 | US |