Claims
- 1. A device for treating ischemic tissue comprising
an elongate shaft having proximal and distal ends, a lumen extending therebetween; a control structure operably connected to the shaft for actuation of the device by user activation; at least one injury effector adjacent the elongate shaft's distal end, and capable of inducing a mechanical or energy injury produced at a tissue site in response to actuation by the control structure; when the shaft's distal end is placed against a tissue surface; at least one therapeutic-substance delivery effector carried on the elongate shaft at the distal end thereof, said therapeutic-substance delivery effector having at least one therapeutic-substance delivery port through which therapeutic-substance can be delivered from the effector into tissue against which the effector is placed, each of said one or more injury-treatment effectors and said one or more therapeutic-substance delivery ports being spaced from one another at selected positions and adapted to be placed simultaneously against such tissues; and at least one therapeutic-substance source having a reservoir for storing a substance and in substance communication with said therapeutic-substance delivery ports, and responsive to said control structure to eject therapeutic-substance from said reservoir through said one or more ports into such tissue,
wherein, said control structure, when activated by a user, operates to actuate said injury-treatment effector, and additionally actuates said therapeutic-substance source to expel therapeutic-substance through said one or more ports to create one or more sites of therapeutic-substance infusion in the tissue at defined spaced-apart locations with respect to the created one or more sites of injury.
- 2. The device of claim 1 further comprising a third treatment effector for creating a treatment position marker.
- 3. The device of claim 2 wherein the third treatment effector is separate from the injury and therapeutic-substance delivery effectors.
- 4. The device of claim 2 wherein the marking effector is combined with either the injury, or therapeutic-substance delivery, or injury and therapeutic-substance delivery effectors.
- 5. The device of claim I wherein the injury and therapeutic-substance delivery effectors actuate simultaneously.
- 6. The device of claim 1 wherein the injury and therapeutic-substance delivery effectors actuate sequentially.
- 7. The device of claims 2, 3, or 4 wherein the injury, therapeutic-substance delivery, and position-marking effectors actuate simultaneously.
- 8. The device of claims 2, 3, or 4 wherein the injury, therapeutic-substance delivery, and position-marking effectors actuate sequentially.
- 9. The device of claims 2, 3, or 4 wherein the position-marking effector actuates independently from the injury effectors or therapeutic-substance delivery effectors.
- 10. The device of claim 1 wherein the therapeutic-substance-source is actuated independent of the actuation of the therapeutic-substance delivery effectors.
- 11. The device of claim 1 wherein the therapeutic-substance-source is actuated simultaneous to the actuation of the therapeutic-substance delivery effectors.
- 12. The device of claim 1 wherein the elongate shaft further comprises a steerable distal end.
- 13. The device of claim 1 further comprising an optical viewing port located at the elongate shaft's distal end in optical communication with an imaging device.
- 14. The device of claim 1 wherein the elongate shaft further comprises a contact sensor located on the elongate shaft's distal end.
- 15. The device of claim 1 wherein the elongate shaft further comprises a positioning aid located on the elongate shaft's distal end.
- 16. The device of claim 1 wherein the elongate shaft is a catheter.
- 17. The device of claim 1 wherein the elongate shaft is an endoscope.
- 18. The device of claim 1 wherein the elongate shaft is an open surgical hand held device.
- 19. A method of treating ischemic tissue comprising the steps of,
identifying target tissue regions of ischemic tissue, providing a device that can upon activation and by a single placement of the device, cause an injury to at least one site of target tissue different than at least one site of target tissue where a therapeutic-substance is delivered, placing the device against the identified target tissue, and, activating the device to cause injury to selected sites within the target tissue, and to cause therapeutic-substance to be delivered to regions in the target tissue at preselected sites away from the sites of injury.
- 20. A method for treating a target tissue comprising the steps of
identifying the target tissue producing one or more sites of injury within said region, where multiple sites of injury, if produced, are at known relative positions with respect to one another, and infusing therapeutic-substance into on or more sites different than the one or more sites of injury.
- 21. A method for treating ischemic tissue comprising the steps of
identifying a region of ischemic tissue within a patient's body producing one or more sites of injury within such region, where multiple sites, if produced, are at known relative positions with respect to one another, infusing therapeutic-substance into one or more sites different from such injury sites and at known positions away from such injury sites.
RELATED APPLICATION
[0001] This application claims priority to U.S. Provisional Patent Application Ser. No. 60/214,053 filed on Jun. 26, 2000 which is incorporated in its entirety herein by reference.
Provisional Applications (1)
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Number |
Date |
Country |
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60214053 |
Jun 2000 |
US |