The present invention refers to a method, and to a device for the implementation of said method, for the objective characterization of the symptoms of Parkinson's disease.
The invention is part of the technical field of medicine, in particular neurology.
Parkinson's disease is the most frequent neurodegenerative disease after Alzheimer's disease. The diagnosis of Parkinson's disease is essentially clinical and currently based on the objective and anamnestic identification of the characteristic signs and symptoms of the disease and on the exclusion of any atypical symptoms.
There are specific diagnostic criteria, developed over the years, in order to standardize and systematize the diagnosis of Parkinson's disease.
These methods objectively characterize the symptoms of Parkinson's disease, but do not integrate movement, tremor, facial and vocal analysis data and, above all, do not provide real-time data to monitor the progress of the disease moment by moment.
Patients with Parkinson's disease can experience fluctuations in their motor status during the day going from an OFF phase, in which parkinsonian symptoms such as rigidity, tremor and bradykinesia emerge, to an ON phase in which these symptoms improve significantly. marked, and also to a phase characterized by involuntary movements called dyskinesias (DIS).
Object of the present invention is providing a method and a system, respectively in accordance with claims 1 and 2, suitable for characterizing the motor state of the patient.
The method for the objective characterization of the symptoms of Parkinson's disease, called characterization taking place through the analysis of the motor state of patients with said Parkinson's disease, in which said motor state may be in one of the following phases:
is characterized by using voice analysis, facial analysis, tremor analysis and movement analysis of said patient as parameters for detecting said symptoms, an algorithm being provided for using said detection parameters to determine the motor state of said patient.
The system for the objective characterization of the symptoms of Parkinson's disease includes:
According to a preferred embodiment, said camera, said recorder, said processing device, said display and the relative software are integrated in a palmtop/smartphone, whereby the electronic bracelet sends the combined data of movement and tremor analysis directly to said palmtop/smartphone, said palmtop/smartphone being provided with a display able to visualize the motor state of the patient: ON, OFF, DIS.
Preferred embodiments and non-trivial variants of the present invention form the subject of the dependent claims.
The advantage deriving from the use of the invention consists in the fact that it guarantees continuous monitoring 24 hours a day, integrating kinematics data with facial and voice analysis data.
It will be immediately obvious that innumerable variations and modifications (for example relating to shape, dimensions, arrangements and parts with equivalent functionality) can be made to what is described, without departing from the scope of the invention, as appears from the attached claims.
It is understood that all attached claims form an integral part of the present description.
The present invention will be better described by a preferred embodiment, given by way of non-limiting example, with reference to the attached drawings, in which:
With reference to
This system is used for the objective characterization of the symptoms of Parkinson's disease.
The operation of the system (1) is divided into the following steps.
Step 1—The electronic bracelet (2) continuously records the patient's movement (10) and tremor (11) data.
Step 2—When the patient perceives a state of OFF or marked dyskinesias (DIS), he uses the camera (3) to capture facial expressions and the recorder (4) to record his voice.
Step 3—The processing device (5) receives from the electronic bracelet (2), the camera (3) and the recorder (4) the combined data of movement (10), tremor (11), facial images (12) and item (13) and, through the motor state characterization algorithm, identifies the patient's motor state (14) and displays it on the display (6): ON, OFF, DIS.
According to a preferred embodiment (la) shown in
Number | Date | Country | Kind |
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102020000021382 | Sep 2020 | IT | national |
Filing Document | Filing Date | Country | Kind |
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PCT/IT2021/050160 | 5/25/2021 | WO |