The invention relates to a method and a packaging device for packaging discrete medicaments in pouches. Such packaging devices are typically used for packaging large amounts of pouches with a small selection of discrete medicaments, each to be administered at once to a patient.
The filled pouches are interconnected to form a long string. The state of the art packaging devices are very reliable in producing the large amounts of pouches at a high speed, whereby in practice one human operator can process many orders each having one or multiple interconnected pouches that are separated from the long string.
A disadvantage of the known packaging device is that when errors are detected by the packaging device that may affect the quality or the pharmaceutical content of the pouches, the operator needs to be warned to start an intervention. During the intervention the faulty pouches need to be traced back and discarded, which is very labor intensive. When there are small orders between large orders, there is a risk that the human operator misses it and that the small order erroneously remains attached to a large order.
It is an object of the present invention to provide a method and a packaging device for packaging discrete medicaments in pouches, in which a human intervention can be performed effectively and efficiently.
Alternatively, it is an object of the present invention to provide a method and a packaging device that facilitates the human handling of both small orders and large orders.
The invention provides a method for packaging discrete medicaments in pouches in a packaging device configured to form and fill the pouches in an elongated web,
When according to the method of the invention the elongated web is formed that is subsequently handled by an operator, the operator immediately sees from the fault indication or the fault symbol on an empty pouch that a faulty pouch is present. The operator can immediately trace back the faulty pouch and discard it, for example by counting forwards from the fault indication or the fault symbol.
In an embodiment the fault is a faulty pouch, and the printing of the fault indication or a fault symbol on the elongated web is performed upstream from the detected faulty pouch.
In an embodiment the transporting of the elongated web along the web trajectory is done by means of a web drive. In an embodiment the printing information on the elongated web is done by means of a printer at a print station.
In an embodiment the packaging device comprises a transport monitoring device, preferably comprising an encoder, for monitoring the transport of the elongated web along the web trajectory for the step of inspecting the elongated web to determine whether there is a fault related to an alignment of the elongated web.
In an embodiment the packaging device comprises an inspection station along the web trajectory for the step of inspecting the elongated web to determine whether there is a fault related to the elongated web.
In an embodiment the inspection station comprises one or more of an inspection camera, an inspection sensor, an inspection photo sensor, an inspection laser photo sensor, or an ultrasonic inspection sensor, and the inspecting comprises an inspection of the elongated web by said inspection camera, inspection sensor, inspection photo sensor, inspection laser photo sensor or ultrasonic inspection sensor.
In an embodiment the method further comprises applying a heat sealing in the elongated web to enclose the medicaments that have been fed to the elongated web.
In an embodiment the step of inspecting the elongated web to determine whether there is a fault related to the elongated web comprises sensing a faulty heat sealing.
In an embodiment the method further comprises applying a separation perforation line in the elongated web between pouches to be formed, and wherein the step of inspecting the elongated web to determine whether there is a fault related to the elongated web comprises detecting a faulty separation perforation line.
In an embodiment the method further comprises forming a tear notch, and wherein the step of inspecting the elongated web to determine whether there is a fault related to the elongated web comprises detecting a faulty tear notch.
In an embodiment the elongated web comprises a foil that forms a front side and a back side between which the medicaments are received.
In an embodiment thereof the foil is folded back onto itself, whereby the front side continues into the back side via a fold that forms a bottom edge of the elongated web.
In an embodiment the foil comprises a printable plastic.
In an embodiment the step of printing a fault indication or a fault symbol on the elongated web comprises printing the fault indication or fault symbol on the elongated web upstream from the fault.
The invention further provides a computer program product having a non-transitory computer readable medium with instructions saved thereon that, when executed by a processor, cause a packaging device to perform the method according to the invention.
The invention further provides a packaging device for packaging discrete medicaments in pouches, the packaging device comprising:
In an embodiment the fault is one or more of: a faulty pouch, a faulty seal, a faulty separation perforation, a faulty tear notch and a misalignment of the elongated web with respect to one of the stations.
In an embodiment the inspection station comprises one or more of an inspection camera, an inspection sensor, an inspection photo sensor, an inspection laser photo sensor, or an ultrasonic inspection sensor.
In an embodiment the packaging device further comprises a perforation station along the web trajectory to apply one or more separation perforation and/or tear lines in the elongated web.
In an embodiment thereof the packaging device further comprises a sealing station for sealing the pouches in the elongated web.
A second aspect provides a method for packaging discrete medicaments in pouches in a packaging device,
In the method according to the invention an order with is smaller than the minimal order size can easily be identified by the second amount of empty pouches.
In an embodiment the printer prints information on the empty pouches that is related to the empty status of the empty pouches.
The invention further provides a computer program product having a non-transitory computer readable medium with instructions saved thereon that, when executed by a processor, cause a packaging device to perform the method according to the second aspect.
The invention further provides a packaging device for packaging discrete medicaments in pouches, wherein the packaging device is configured to form and fill the pouches in an elongated web to contain the medicaments,
The various aspects and features described and shown in the specification can be applied, individually, wherever possible. These individual aspects, in particular the aspects and features described in the attached dependent claims, can be made subject of divisional patent applications.
The feeding device 1 comprises a frame 2 and a horizontally extending supporting disc 3 that supports multiple radially extending arrays 5 each having multiple canisters or feeder units 6. The feeding device 1 comprises an elongated collecting hopper 7 under the supporting disc 3 that is connected to a position control motor 4, such as a servo drive, on the frame 2 via a radially extending arm 9 to be rotated around a vertical axis. Each of the feeder units 6 can be filled with batches of different discrete medicaments. The feeder units 6 are configured to discharge individual discrete medicaments, which are collected by the collecting hopper 7 that is rotated under the discharging feeder unit 6 by means of the position control motor 4. In this manner a selection of discrete medicaments 10 is counted out and compiled to be administered to a patient at once. The collecting hopper 7 merges into a hopper outlet 8 to supply the selection of discrete medicaments 10 to a packaging device for packing each of the compiled selection of discrete medicaments 10 in pouches 150. The collecting hopper 7 comprises a (not shown) hopper release valve with an actuator at the hopper outlet 8 for controlled release of the compiled selection of discrete medicaments 10.
The packaging device 20 is shown in more detail in
The elongated web 100 comprises a printable, plastic foil 101 that is folded back onto itself, whereby the elongated web 100 comprises a front side 102 that continues into a back side 104 via a fold that forms a bottom edge 103. The front side 102 and the back side 103 both have a top edge 105 at the same height with respect to the bottom edge 103.
During the transport through the packaging device the elongated web 100 is provided with subsequent straight separation perforation lines 120 between the heat sealings 110. The separation perforation lines 120 extend as from the bottom edge 103 over more than half of the distance between the bottom edge 105 and the top edges 105. In this example the separation perforation lines 120 extend over more than 70% of the distance between the bottom edge 105 and the top edges 105, though that could vary in other systems depending on the size, type of foil used, etc. Thereby foil bridges 121 are formed between the separation perforation lines 120 and the top edges 105.
During the transport through the packaging device the elongated web 100 is provided with subsequent tear notches 122 that start at and extend transverse to the separation perforation lines 120. The tear notches 122 extend with respect to the bottom edge 103 at a height close to but below the top heat seal 113.
The elongated web 100 defines printable areas 117 on the front side 102 within the heat sealings 110. Behind the printable area 117 the elongated web 100 forms sealed off enclosures between the bottom edge 103 and the heat sealings 110 to contain and preserve the selection of discrete medicaments 10.
After transport through the packaging device 20 the elongated web 100 can be divided manually by tearing off the separation perforation lines 120, followed by tearing the foil bridges 121 to obtain a pouch 150 or a series of interconnected pouches 150. The separated pouches 150 can be opened manually by tearing off the top heat seal 113, which is initialized at the tear notch 122.
As shown in
The packaging device 20 comprises a transport monitoring device, in this example an encoder 72 having a monitoring wheel against the elongated web 100 to monitor the transport of the elongated web 100 in the transport direction T. The transport monitoring device may be part of the inspection station 70, or a separate device. The encoder 72 may be used as an additional or alternative inspection sensor to inspect the elongated web 100 in terms of misalignment or shifting of the position of the elongated web 100 with respect to the movement as imposed by the web drive 23.
As schematically shown in
The electronic controller 80 is programmed to perform a normal processing method, a fault detection method and a small order processing method.
For performing the normal processing method as schematically shown in
The electronic controller 80 is programmed to control the heat seal stamps 51 at the subsequent sealing station 50. In the previous cycle the heat seal stamps 51 had already made the front heat seal 111. The electronic controller 80 is programmed to actuate the heat seal stamps 51 to move in direction A against the elongated web 100 and back to complete the entire heat sealing 110 and to form the front heat seal 111 of the next selection of discrete medicaments that is fed by the hopper outlet 8. The electronic controller 80 is programmed to control the actuation of the perforation anvils 61 to move in direction B against the elongated web 100 and back to form the separation perforation line 120 and the tear notch 122 to define the pouch 150 that contains the selection of discrete medicaments and with the matching dedicated information on the printable area 117. The electronic controller 80 is programmed to detect faults in the formed pouches 150, and in absence thereof to continue the process to form a long string of interconnected pouches 150. These can be subsequently handled either by a human operator or another machine or robot.
The electronic controller 80 is programmed to power the web drive 23 while inspecting, examining or monitoring the transport of the elongated web 100 by means of the encoder 72 so as to detect related errors for example a misalignment of the elongated web 100 with respect to the movement as imposed by the web drive 23.
The electronic controller 80 is programmed to respond to errors originating from other devices or modules of the feeder device 1, such as the feeder units 6, the position control motor 4 and the collection hopper 7, for example the hopper release valve.
For performing the fault detection method as shown in
As shown in
As shown in
Information of the error may be stored in the memory of the controller 80 and/or presented to the human or robotic operator to indicate which pouches 150 are affected. The operator may for example be notified of the number of pouches 150b-150h between the ninth pouch 150j and the faulty first pouch 150a and/or the number of pouches 150a-150c that are affected.
For performing the small order processing method as shown in
The systems and methods according to aspects of the disclosed subject matter may also utilize a variety of special purpose computer and control systems, communications devices, networks and/or digital/logic devices for operation. Each may, in turn, be configurable to utilize a suitable computing/controller device that can be manufactured with, loaded with and/or fetch from some storage device, and then execute, instructions that cause the computing/controller device to perform a method according to aspects of the disclosed subject matter.
While the description refers to medicaments, tablets, etc., the devices and methods could be used for dispensing other types of solid discrete items for separation and packaging.
It is to be understood that the above description is included to illustrate the operation of the preferred embodiments and is not meant to limit the scope of the invention. From the above discussion, many variations will be apparent to one skilled in the art that would yet be encompassed by the spirit and scope of the present invention.
Filing Document | Filing Date | Country | Kind |
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PCT/NL2022/050360 | 6/22/2022 | WO |
Number | Date | Country | |
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Parent | 17353948 | Jun 2021 | US |
Child | 18572219 | US |