Prior to conducting a radiology study, a radiologist may examine one or more relevant prior imaging studies in order to establish proper context for the current study. Establishing context may be a non-trivial task, particularly in the case of cancer patients, whose histories may include related findings across multiple clinical episodes. Existing radiology equipment provides a patient's past studies along a basic timeline, which may enhance the difficulty of establishing proper context.
The exemplary embodiments may be further understood with reference to the following description and the related appended drawings, wherein like elements are provided with the same reference numerals. Specifically, the exemplary embodiments relate to methods and systems for visualization of complex patient histories of imaging studies.
Radiologists typically must familiarize themselves with a large number of prior studies in order to diagnose and treat patients in an effective manner. The use of prior studies is required in order to establish proper context for a current study. In particular, cancer patients may frequently undergo imaging studies, resulting in a large number of prior studies to be reviewed by a radiologist. The designation “radiologist” is used throughout this description to refer to the individual who is reviewing a patient's medical records, but it will be apparent to those of skill in the art that the individual may alternatively be any other appropriate user, such as a doctor, nurse, or other medical professional.
Prior art solutions typically display previous studies along a basic timeline.
At most, prior solutions may group all studies of the same type (e.g., all studies having the same modality and body part) along a more focused timeline. Timeline 120, on the left hand side of
The process of reviewing prior studies typically involves opening one or more prior reports, which typically include images and accompanying text in a narrative form. However, the generalized views presented by the prior art as shown in
The system 200 also includes exemplary modules, which may be modules of code that are stored in the memory 220 and executed by the processor 210 to perform functions that will be described below with reference to the method 300. These include an extraction module 250 extracting relevant information from the prior study data 240, a grouping module 260 grouping related studies in a predefined or user-specified manner, and an interface module 270 generating a graphical display enabling the radiologist to visualize study groupings in the manner that will be described in further detail below. Those of skill in the art will understand that the delineation of the performance of method 300 as by three separate modules is only exemplary and that the functions may alternately be performed by an integrated software application, or multiple applications having their functions delineated differently from the manner described herein.
In step 320, the extraction module 250 extracts from the patient's prior art studies contextual characteristics of the studies. Characteristics may include body part, reason for exam, modality, etc. The characteristics may be stored in, and the extraction module 250 may extract the characteristics from, both the metadata concerning the studies and the content of the reports, which, as noted above, may comprise text in a narrative format.
As noted above, metadata of the prior studies may commonly be stored in accordance with the DICOM standard. Various characteristics may be extracted from various DICOM attributes (or, as will be apparent to those of skill in the art, other metadata elements when data is stored in a format other than DICOM). For example, a study modality characteristic can be extracted directly from a DICOM attribute and may correspond to DICOM Modality field (0008, 0060). A body part of study characteristic can be extracted directly from a DICOM attribute and may correspond to DICOM Body Part Examined field (0018, 0015).
Some characteristics may be determined by extracting metadata and applying natural language processing (“NLP”), such as using the MetaMap NLP engine, to the extracted text. For example, a reason for exam characteristic can be determined by extracting text from the DICOM tag (0032, 1030) and using NLP techniques to extract diagnostic terms from the narrative text therein. Similarly, an anatomy of study characteristic may be determined by applying NLP techniques to extract a specific body part from narrative descriptions found in the Study Description DICOM tag (0008, 1030), the Protocol Name DICOM tag (0018, 1030), and the Series Description DICOM tag (0008, 103e). It will be apparent to those of skill in the art that the specific characteristics extracted from metadata discussed above are only exemplary, and that other characteristics may be extracted in other embodiments. Continuing with the exemplary embodiment in which metadata is in the DICOM standard, other useful tags may include Procedure Code, Requested Procedure Code, and Scheduled Procedure code.
As noted above, in addition to metadata, the content of the reports, including reason for exam and comparison studies, may be extracted from the narrative text of the prior studies. As described above, an NLP technique may be used to perform this extraction. NLP may be capable of determining sectional structure of the reports, including sections, paragraphs, and sentences. This may include using a maximum entropy classifier that assigns, to each end-of-sentence character (e.g., a period, an exclamation mark, a question mark, a colon, or a backslash-n) one of four labels:
1) The character marks the end of a sentence and the sentence is a section header
2) The character marks the end of a sentence and the sentence ends a paragraph
3) The character marks the end of a sentence and the sentence is neither a section header nor the last sentence of a paragraph
4) The character does not mark the end of a sentence
Section headers may be normalized with respect to five classes: technique, comparison, findings, impressions, and none. As used here, “normalized” means that entries in different reports, the format of which may vary from institution to institution or radiologist to radiologist (e.g., one institution might call the findings section “FINDINGS,” another might call it “FINDING,” while still another might call it “OBSERVATIONS,” etc.), are updated to fit into the standard classes noted above. Other than section headers, sentences may be grouped into paragraphs. The first sentence in each paragraph may be compared against a list of paragraph headers (e.g., “liver”, “spleen”, “lungs”, etc.), and sentences that match an entry in the list are marked as being paragraph headers. In addition to the above, diagnosis-related terms and anatomy-related terms may be extracted from a clinical history section, and dates of comparison studies may be extracted.
In step 330, the grouping module 260 receives the studies and extracted characteristics determined by the extraction module 250 in step 320. This may occur through any standard means for passing data from one computing routine to another. In step 340, the grouping module 260 groups one or more subsets of the studies for subsequent display based on the characteristics corresponding to the studies that comprise the one or more subsets. As will be described hereinafter, the characteristics may be used to group the studies into groups that are related to one another. The grouping may be in a manner that is preconfigured or user-specified. The following describes a variety of exemplary manners for grouping the studies, but it will be apparent to those of skill in the art that other groupings may be possible without departing from the broader principles described herein.
In one exemplary grouping, body part characteristics extracted from the studies may be mapped to organ systems within the human body. By performing such mapping, studies may be grouped by organ and subsequently presented to the radiologist in organ-based groupings. In another exemplary grouping, grouping may be made based on diagnostic terms extracted from “reason for exam” or “clinical history” sections of the reports. This may result in a grouping of prior studies that are related to a same basis for examination.
In another exemplary grouping, characteristics extracted from comparison sections of study reports may be used to group studies that were described as relevant to one another. For example, a comparison section of a report of a given prior study may contain dates of other prior studies that were used for comparison to the given prior study. It will be apparent to those of skill in the art that a prior study may be used and referenced in a report because there is some relationship between the current study and the prior study. Thus, these extracted characteristics may be used to group studies that have an explicit relationship to one another made in the reports.
In another embodiment, prior to grouping, body parts extracted from the reports may be normalized using an ontology such as Systematized Nomenclature of Medicine (“SNOMED”) or Unified Medical Language System (“UMLS”). For example, the knowledge from such an ontology may be used to determine that one study that has an extracted characteristic “kidney” should be grouped with another study having an extracted characteristic “renal”. Similarly, association relationships (e.g., “is-part-of” relationships) contained in such an ontology may be used to determine that two body parts are related and that studies having characteristics of the two body parts should be grouped together. For example, the relationships from such an ontology may be used to determine that a study that has an extracted characteristic “liver” should be grouped with another study having an extracted characteristic “abdomen”.
In another embodiment, a data-driven approach may be used to define a matrix and compare a feature vector of a current study with feature vectors of prior studies. Such a matrix could contain feature vectors from the current study and from prior studies. Each column of the matrix may represent a feature extracted from study metadata such as DICOM tags (e.g., modality, body part 1, body part 2, etc.), as well as words or phrases extracted from the report; each row in the matrix may represent extracted feature information for a single study. Statistical clustering techniques that are known in the art (e.g., using k-means) may then be applied to the various feature vectors to identify groups of studies that are similar.
In step 350, the interface module 270 receives the studies and one or more groupings thereof determined by the grouping module 260 in step 340. As noted above with reference to step 330, this may occur through any standard means for passing data from one computing routine to another. In step 360, the interface module 270 generates a visualization based on the one or more groupings identified by the grouping module 260 and provides the visualization to the radiologist by the user interface 230. In the common three-display embodiment of a user interface 230 described above, the interface module 270 may provide this visualization on the right-hand display.
The interface module 270 may display the grouped studies in a variety of specific manners. In one exemplary embodiment, the interface module 270 may provide to the user interface 230 a visualization showing study timelines in conjunction with an illustration of a human.
In another exemplary embodiment, the interface module 270 may provide to the user interface 230 a visualization showing study timelines grouped based on explicit references to prior studies. As noted above, this may be accomplished using information extracted from the Comparison sections of study reports.
In another exemplary embodiment, the interface module 270 may provide to the user interface 230 a visualization showing study timelines grouped by modality and body part. As noted above, this may be accomplished using information extracted from the Comparison sections of study reports.
As noted above, the visualization 600 shows the same studies as the visualization 500 of
In another exemplary embodiment, the interface module 270 may provide to the user interface 230 a visualization showing study timelines grouped by body part without regard to modality. As noted above, this may be accomplished using information extracted from the Comparison sections of study reports.
As noted above, the visualization 700 shows the same studies as the visualization 500 of
It will be apparent to those of skill in the art that the visualizations 400, 500, 600 and 700 described above are only exemplary, and that other criteria for study grouping may be used without deviating from the broader principles of the exemplary embodiments. The user interface 230 may also enable the radiologist to correct or update study associations using a “drag and drop” or other interface. For example, a radiologist viewing the visualization 600, including timeline 610 and ungrouped study 662, may elect to associate study 662 with timeline 610; it will be apparent to those of skill in the art that this will result in a timeline similar to timeline 710 of visualization 700. Additionally, the radiologist may interact with the user interface 230 to select one or more of the studies (e.g., a single study, a portion of a selected timeline, an entire selected timeline, a plurality of selected timelines, etc.) and launch the studies for interpretation.
The visualizations that may be provided by the exemplary embodiments may aid a radiologist in establishing clinical context for a current study in two ways. First, the study groupings themselves may enable the radiologist to gain an overall understanding of the patient's history by providing a general overview of the type of scans that have been conducted on the patient over a desired time interval. Second, because the studies may be presented to the radiologist in grouped subsets rather than wholesale as shown in
Those of skill in the art will understand that the above-described exemplary embodiments may be implemented in any number of manners, including as a software module, as a combination of hardware and software, etc. For example, the exemplary method 300 may be embodied in a program stored in a non-transitory storage medium and containing lines of code that, when compiled, may be executed by a processor. Additionally, it will be apparent to those of skill in the art that though this disclosure makes reference to specific types of medical imaging studies, the broader principles described herein may be equally applicable to any type of medical imaging study known to those of skill in the art. This may include x-ray studies or other types of radiographic studies, RF studies, CT studies, CR studies, magnetic resonance imaging (“MRI”) studies, ultrasound studies, position emission tomography (“PET”) studies or other types of nuclear imaging studies, photoacoustic studies, thermographic studies, echocardiographic studies, functional near-infrared spectroscope (“FNIR”) studies, or any other type of medical imaging study not expressly mentioned herein.
It will be apparent to those skilled in the art that various modifications may be made to the exemplary embodiments, without departing from the spirit or the scope of the invention. Thus, it is intended that the present invention cover modifications and variations of this invention provided they come within the scope of the appended claims and their equivalents.
Filing Document | Filing Date | Country | Kind |
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PCT/IB2015/052526 | 4/8/2015 | WO | 00 |
Number | Date | Country | |
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61980768 | Apr 2014 | US |