Adams et al., "The Biochemistry of the Nucleic Acids," .sctn.7.2.1, 259-260; 11th Ed., (1992). |
Sproat and Lamond, "2'-0-Methyloligoribonucleotides:synthesis and applications," pp. 49-86, from Eckstein, "Oligonucleotides and Analogues: A Practical Approach," Chapter 3, (1991). |
Uhlmann et al., Chemical Reviews, 90(4):558 (1990). |
Blommers et al., "An approach to the structure determination of nucleic acid analogues hybridized to RNA . . . ," Nucl. Acid. Res., 22(20):4187-4194 (1994). |
Boiziau et al., "Antisense 2'-O-alkyl oligoribonucleotides are efficient inhibitors of reverse transcription," Nucl. Acid. Res., 23(1):64-71 (1995). |
Bonham et al., "An assesment of the antisense properties of RNase H-competent and steric-blocking oligomers," Nucl. Acid. Res., 23(7):1197-1203 (1995). |
Conrad et al., "Enzymatic synthesis of 2'-modified nucleic acids: indentification of important phosphate . . . ," Nucl. Acid. Res., 23(11):1845-1853 (1995). |
Cotten et al., "2'-O-methyl,2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides . . . ," Nucl. Acid. Res., 19(10):2629-2635 (1991). |
Dominski et al., "Identification and Characterization by Antisense Oligonucleotides of Exon and Intron . . . ," Mol. Cell. Biol., 14(11):7445-7454 (1994). |
Ecker et al., "Rational screening of oligonucleotide combinatorial libraries for drug discovery," Nucl. Acid. Res., 21(8):1853-1856 (1993). |
Johansson et al., "Target-specific arrest of mRNA translation by antisense 2'-O-alkyloligoribonucleotides," Nucl. Acid. Res., 22(22):4591-4598 (1994). |
Kawasaki et al., "Synthesis and Biophysical Studies of 2'-dRIBO-2'-F Modified Oligonucleotides,," Presentation/Seminar--ISIS Pharmaceuticals (Jan. 1991). |
Kean et al., "Interactions of oligonucleotide analogs containing methylphosphonate internucleotide linkages . . . ," Nucl. Acid. Res., 22(21):4497-4503 (1994). |
Keller et al., "Synthesis and hybridization properties of oligonucleotides containing 2'-O-modified ribonucleotides," Nucl. Acid. Res., 21(19):4499-4505 (1993). |
Larrouy et al., "RNase H is responsible for the non-specific inhibition of in vitro translation by 2'-O-alkyl . . . ," Nucl. Acid. Res., 23(17):3434-3440 (1995). |
Shibahara et al., "Site-directed cleavage of RNA," Nucl. Acid. Res., 15(11):4403-4415 (1987). |
Wang et al., "Relative stabilities of triple helices composed of combinations of DNA, RNA and 2'-O-methyl-RNA . . . ," Nucl. Acid. Res., 23(7):1157-1164 (1995). |
Bobst et al., "Effect of the Methylation of the 2'-Hydroxyl Groups in Polyadenylic Acid on its Structure in Weakly Acidic and Neutral Solutions and on its Capability to Form Ordered Complexes with Polyuridylic Acid", J. Mol. Biol., 46:221-234 (1969). |
Burd et al., "Conserved Structures and Diversity of Functions of RNA-Binding Proteins", Science, 265:615-621 (1994). |
Chiang et al., "Antisense Oligonucleotides Inhibit Intercellular Adhesion Molecule 1 Expression by Two Distinct Mechanisms", J. Biol. Chem., 266(27):18162-18171 (1991). |
Corey, "48000-fold Acceleration of Hybridization by Chemically Modified Oligonucleotides", J. Am. Chem. Soc., 117(36):9373-9374 (1995). |
Cummins et al., "Characterization of Fully 2'-modified Oligoribonucleotide Hetero- and Homoduplex Hybridization and Nuclease Sensitivity", Nucleic Acids Research, 23(11):2019-2024 (1995). |
Dean et al., "Inhibition of Protein Kinase C-.alpha. Expression in Human A549 Cells by Antisense Oligonucleotides Inhibits Induction of Intercellular Adhesion Molecule 1 (ICAM-1) mRNA by Phorbol Esters", J. Biol. Chem., 269(23):16416-16426 (1991). |
Ecker et al., "Pseudo-Half-Knot Formation with RNA", Science, 257:958-961 (1992). |
Goodchild, "Conjugates of Oligonucleotides and Modified Oligonucleotides: A Review of Their Synthesis and Properties", Bioconjugate Chemistry, 1(3):165-187 (1990). |
Hou et al., "Inhibition of tRNA Aminoacylation by 2'-O-Methyl Oligonucleotides", Biochemistry, 35(48):15340-15348 (1996). |
Inoue et al., "Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H", FEBS Letter, 215(2):327-330, 1987. |
Inoue et al., "Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides", Nucleic Acids Research, 15(15):6131-6148 (1987). |
Iribarren et al., "2'-O-Alkyl oligoribonucleotides as antisense probes", Proc. Natl. Acad. Sci, USA, 87:7747-7751 (1990). |
Knorre et al., "Oligonucleotides Linked to Reactive Groups", Oligodeoxynucleotides, Chpt. 8, pp. 173-196 (1989). |
Lammond et al., "Antisense oligonucleotides made of 2'-O-alkylRNA: their properties and applications in RNA biochemistry", FEBS Letter, 325(1, 2):123-126 (1993). |
Leslie et al., "Structure of the Single-stranded Polyribonucleotide Poly(2'-O-methylcytidylic Acid)", J. Mol. Biol., 119:399-414 (1978). |
Lesnik et al., "Oligodeoxynucleotides Containing 2'-O-Modified Adenosine: Synthesis and Effects on Stability of DNA:RNA Duplexes", Biochemistry, 32(30):7832-7838 (1993). |
Markiewicz et al., "The modified nucleosides of tRNAs. II. Synthesis of 2'-O-methylcytidylyl (3'-5') cytidine", Nucleic Acids Research, 2(6):951-960 (1975). |
Meinkoth et al., "Hybridization of Nucleic Acids Immobilized on Solid Supports", Analytical Biochemistry, 138:267-284 (1984). |
Miller et al., "Effects of a Trinucleotide Ethyl Phosphotriester, G.sup.m p(Et)G.sup.m p(Et)U, on Mammalian Cells in Culture", Biochemistry, 16(9):1988-1996 (1977). |
Monia et al, "Evaluation of 2'-Modified Oligonucleotides Containing 2'-Deoxy Gaps as Antisense Inhibitors of Gene Expression", J. Biol. Chem., 268(19):14514-14522 (1993). |
Ohtsuka et al., "Studies on Transfer Ribonucleic Acids and Related Compounds. XLI..sup.1) Synthesis of tRNA Fragments containing Modified Nucleosides", Chem. Pharm. Bull., 31(2):513-520 (1983). |
Pilet et al., "Structural Parameters of Single and Double Stranded Helical Polyribonucleotides", Biochem. Biophys. Res. Comm., 52(2):517-523 (1973). |
Sproat et al., "Highly efficient chemical synthesis of 2'-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases", Nucleic Acids Research, 17(9):3373-3386 (1989). |
Suzuki, "SPKK, a new nucleic acid-binding unit of protein found in histone", EMBOJ, 8:797-804 (1989). |
Thibaudeau et al., "How Does the Electronegativity of the Substituent Dictate the Strength of the Gauche Effect?", J. Am. Chem. Soc., 116(9):4038-4043 (1994). |
Wei et al., "Hybridization properties of oligodeoxynucleotide pairs bridged by polyarginine peptides", Nucleic Acids Res., 24(4):655-661 (1996). |
Yamaguchi et al., "Chemical synthesis of the 5'-terminal part bearing cap structure of messenger RNA of cytoplasmic polyhedrosis virus (CPV): m.sup.7 G.sup.5, pppAmpG and m.sup.7 G.sup.5, pppAmpGpU", Nucleic Acids Res., 12(6):2939-2954 (1984). |
"Role of the Ribose 2'-Hydroxyl Groups for the Stabilization of the Ordered Structures of Ribonucleic Acid", J. Am. Chem. Soc., 91(16): 4603-4604 (1969). |
Meinkoth et al, Hybridization of Nucleic Acids Immobilized on Solid Supports, Analytical Biochemistry 138, 267-284 (1984). |
Winnacker, E.-L., "From Genes To Clones", VCH Verlagsgesellschaft, Weinheim, FRG, 1987, pp. 33-34. |