Claims
- 1. A method for assessing a diabetic patient's relative risk of experiencing a diabetes-associated pathologic condition, said method comprising the steps of:
- (a) measuring the levels of (i) a first compound, characterized by having a .sup.31 P NMR shift of 6.63 at pH 7.5, an .sup.1 H-.sup.31 P coupling of 9.5 Hz and a pKa of 5.5, (ii) a second compound, characterized by having a .sup.31 P NMR shift of 6.74 at pH 7.5, an .sup.1 H-.sup.31 P coupling of 9.5 Hz and a pKa of 5.5, and (iii) sorbitol-3-phosphate in said patient's red blood cells;
- (b) comparing the sum of said levels of measured first and second compounds to said level of measured sorbitol-3-phosphate; and
- (c) determining on the basis of said comparison whether said diabetic patient has an increased or a decreased risk of experiencing said diabetes-associated pathologic condition.
Government Interests
Pursuant to 35 U.S.C. .sctn.202(c), it is hereby acknowledged that the U.S. Government has certain rights in the invention described herein, which was made in part with funds from the National Institute of Health.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4906468 |
Saltiel |
Mar 1990 |
|