Claims
- 1. A method for collecting data pertinent to predictors of heart arrhythmias, said method comprising the steps of:creating an atrioventricular block in the heart of an animal test subject; inducing a myocardial infarction in the heart of the animal test subject; selecting a portion of the myocardium of the animal test subject wherein hyperinnervation is effective for increasing the likelihood of an arrhythmia; stimulating myocardial hyperinnervation in the selected portion of the myocardium of the animal test subject; detecting electrical signals in the heart; detecting an occurrence of the arrhythmia; and recording the electrical signals that had been detected in the heart during at least a period of time prior to the detection of the occurrence of the arrhythmia.
- 2. The method of claim 1, wherein the step of recording the electrical signals is performed to also record electrical signals detected during the arrhythmia.
- 3. The method of claim 1, wherein the step of detecting the occurrence of the arrhythmia is performed to detect ventricular tachycardia.
- 4. The method of claim 1, wherein the step of detecting the occurrence of the arrhythmia is performed to detect ventricular fibrillation.
Parent Case Info
This application is a division of U.S. Ser. No. 09/307,230, filed on May 7, 1999. This application is also related to U. S. Ser. No. 09/884,520, filed Jun. 18, 2001, which is also a divisional application of U.S. Ser. No. 09/307,230, filed May 7, 1999.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
5147294 |
Smith et al. |
Sep 1992 |
A |
5203326 |
Collins |
Apr 1993 |
A |
5921940 |
Verrier et al. |
Jul 1999 |
A |
Foreign Referenced Citations (4)
Number |
Date |
Country |
0047013 |
Mar 1982 |
EP |
0547734 |
Jun 1993 |
EP |
0547734 |
Jun 1993 |
EP |
WO 9907354 |
Feb 1999 |
WO |
Non-Patent Literature Citations (3)
Entry |
PCT International Search Report re PCT/US00/12367, mailed Aug. 11, 2000. |
Malkin, Robert A. et al., The Effect of Inducing Ventricular Fibrillation with 50-hz Pacing Versus T Wave Stimulation on the Ability to Defibrillate, PACE, 21:1093-1097 (May 1998). |
Schwartz, P.J., et al. “Autonomic Mechanisms in Ventricular Fibrillation Induced by Myocardial Ischemia During Exercise in Dogs with Healed Myocardial Infarction. An Experimental Preparation for Sudden Cardiac Death.” PubMed Abstract of Circulation Apr.; 69(4): 790-800 )1984. |