Claims
- 1. A process which comprises contacting and catalytically reacting under essentially anhydrous conditions in the liquid phase an amide with a nitrile according to the equation:
- RCONH.sub.2 +R.sup.1 CN.revreaction.RCN+R.sup.1 CONH.sub.2
- where R and R.sup.1 are not the same and are each selected from
- (1) H, hydrocarbyl, a hydrocarbyl group substituted with: one or more of F, Cl, Br, I, amido, cyano, formyl, hydrocarbylcarbonyl, hydrocarbyloxy, hydrocarbyloxycarbonyl, hydrocarbylcarbonyloxy and dihydrocarbylamino, and
- (2) any of group (1) where one or more H atoms are substituted by a deuterium atom,
- said contacting and reaction being effected in the presence of a catalyst with the formula
- M.sub.m X.sub.a L.sub.b
- where M is selected from Pd and Pt, X contains zero to 10 C atoms, is selected from halogen, H, O, --CO, acyloxy, trihaloacetyloxy, hydroxy, dialkylamino, thio, thioacyl, nitro, tetraalkylboron and tetraalkylaluminum;
- where m is 1 or 2, a is zero, 2 or 4, and b is 0, 1, 2, 3, 4, or 6; when m=1 and a=zero, b is 2, 3 or 4; when m is 1 and a is 2, b is zero or an integer from 1 to 4; when m is 1 and a is 4, b is 4 or 6; when m is 2, a+b are a total of 6;
- where L has the formula TR.sup.2.sub.n, where T is selected from B, N, P, Bi, Al, As, Sb, Li, Na, K, Rb and Cs; each R.sup.2 is the same or different, contains zero to 10 C atoms and is independently selected from H, halogen, nitro, trihalomethyl, acyl, acyloxy, acylthio, hydrocarbyl, hydrocarbyloxy and dihydrocarbylamino; and if T is alkali metal, n is zero; if T is not alkali metal, n is 3 or 4;
- with the proviso that the catalyst can optionally additionally contain as a modifier a compound ZR.sup.2.sub.c where Z is selected from B, N, P, Bi, Al, As and Sb; R.sup.2 is as before defined and c is a number selected to satisfy the valence requirements of Z.
Parent Case Info
This is a continuation of application of Ser. No. 07/758,192 filed Sep. 11, 1991 which is a continuation of application Ser. No. 238,660 filed Aug. 31, 1988, both now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
2461842 |
Olin |
Feb 1949 |
|
4851546 |
Graham et al. |
Jul 1989 |
|
Non-Patent Literature Citations (2)
Entry |
Kirk-Othmer, Encyclopedia of Chemical Technology, Third Edition, vol. 5, John Wiley & Sons, New York, (1979), pp. 16-55. |
Vinokurov, et al., Journal of Organic Chemistry, U.S.S.R., vol. 23, No. 8, Part 2 (Jan. 20, 1988), p. 1602. |
Continuations (2)
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Number |
Date |
Country |
Parent |
758192 |
Sep 1991 |
|
Parent |
238660 |
Aug 1988 |
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