Patent Application
20230221696
The present application claims the benefit under 35 U.S.C. §§ 119(b), 119(e), 120, and/or 365(c) of PCT/EP2021/069470 filed Jul. 13, 2021, which claims priority to German Application No. DE 20 2020 104 037.5 filed Jul. 13, 2020, and to German Application No. DE 10 2020 119 924.4 filed Jul. 28, 2020.
The invention relates to a method for generating a maintenance program for operating a maintenance system on a bioreactor, in particular a bioreactor of a vehicle for transporting people, e.g., a rail vehicle.
Bioreactors are used, among others, to collect wastewater generated during the use of mobile toilet systems. For example, one or more bioreactors can be arranged in a rail vehicle and connected to one or more toilet systems of the rail vehicle to enable temporary disposal of wastewater produced during operation of the rail vehicle.
Conventional bioreactors have a solids tank with a filter basket into which wastewater with solid and liquid components is fed. The filter basket separates the solid from the liquid components. For this purpose, the filter basket has filter elements on the surrounding walls, such as the bottom and side walls, through which liquid elements can flow off and through which solid elements are collected. The solid elements collect at the bottom inside the filter basket separated from the liquid elements and form a filter cake. The liquid elements flow through the filter elements into the solids tank and from there into a liquid tank, which is in fluid communication with the solids tank.
It is known that the solid components in the filter basket settle as a filter cake. First, a filter cake is formed starting at a bottom side of the filter basket and then at the sides of the filter basket. As a result, water is inhibited by the filter cake from flowing into the solids tank. A filter cake with some permeability results in an efficient filtration process. However, an increasingly thick and impermeable filter cake can cause the filter basket to clog. This results in an inefficient filtering process, as the liquid hardly passes through the filter anymore. It is therefore necessary to clean the filter basket of solids at regular intervals to ensure adequate drainage of the water from the solids tank.
It is known to remove the filter cake to counteract this clogging. Often, the filter cake is removed as soon as the first effects of clogging appear. However, this has the disadvantage that inefficient filtration has already taken place. It is also known to check the amount of filter cake from time to time to determine if removal is necessary. However, this has the disadvantage that the check is carried out randomly, and the correct time, i.e., neither too early nor too late, for removal of the filter cake cannot be reliably determined in this way. In addition, it is not possible to reliably assess whether the filter cake is already so impermeable that it must be removed.
One problem with such cleaning processes, however, is that bioreactor systems are usually constructed as closed systems and it is, therefore, very difficult to determine the degree of contamination and the cause of insufficient filtration. Existing bioreactors in particular often do not have interfaces that can be used to read out the information required to determine the cause of a fault or the degree of contamination, or even data that is helpful for this purpose. This is particularly difficult if such a bioreactor is installed on board a vehicle, such as a rail vehicle, in order to clean the dirty water that accumulates there. In such applications, maintenance and assurance of the bioreactor's function is often desired decentrally and without its removal, but at the same time, due to the necessary compactness, access to the bioreactor and to data describing its condition is not possible or only possible at great efforts.
In addition, there are problems in carrying out cleaning, especially with regard to the configuration of the maintenance system and a definition of individual maintenance steps. The handling of the maintenance system is therefore very much subject to the individual operator and thus, for example, a cleaning result may depend on the skill of the respective operator. Furthermore, the characteristics of bioreactors may change during their lifetime, e.g., due to calcification, so that cleaning programs should generally be defined separately in order to achieve consistent maintenance results. In addition, fault conditions can occur that impede or even make it impossible to perform maintenance. Such imponderables must be reacted to in good time by taking adequate measures, such as adjusting an operating parameter of the maintenance system, in order to avoid insufficient cleaning results or even damage to the bioreactor or the maintenance system. However, this requires a high level of expertise on the part of the operating personnel as well as a substantive effort.
Another problem is the provision and maintenance of databases containing the relevant operating information for the maintenance system and at least the bioreactor to be maintained. Due to different bioreactor types, larger amounts of data result, which are not easy to keep track of. In addition, information about the maintenance to be carried out must be available in order to be able to carry out the respective required maintenance professionally at all. There are also dependencies between the individual pieces of information, which must be taken into account before maintenance is carried out by setting suitable operating parameter values for the maintenance system. For example, the amount of liquid used for cleaning should be adapted to the absorption capacity of the bioreactor in order to prevent the bioreactor from overflowing. Furthermore, care must be taken to ensure that the bioreactor is not excessively stressed in the course of maintenance, e.g., due to excessive pump pressure.
All in all, the specific features of mobile bioreactors described above make them extraordinarily complex, which makes professional and reliable maintenance difficult.
It is therefore an object of the present invention to simplify the maintenance of bioreactors, in particular to enable more efficient and reliable maintenance.
The invention solves this problem with a method for generating a maintenance program according to the claims.
A method for generating a maintenance program for the operation of a maintenance system on a bioreactor, in particular, a bioreactor of a vehicle for transporting persons, comprises at least the following steps, which are executed by an electronic data processing means associated with the maintenance system: Acquiring system characteristic data of the maintenance system; acquiring reactor characteristic data of the bioreactor, the reactor characteristic data being received at least in part from a communication interface of the bioreactor; and generating the maintenance program at least on the basis of the system characteristic data and the reactor characteristic data.
The maintenance of bioreactors is simplified in many ways by the provided method for generating a maintenance program. On the one hand, the operation of the maintenance system as such is simplified, because a maintenance program is provided which is specifically tailored to the operation of the maintenance system on a bioreactor on the basis of the system characteristics data and the reactor characteristics data. A complete and correspondingly tedious configuration of the maintenance system by operating personnel qualified for this purpose is thus no longer necessary. In particular, the time required for configuration is reduced, since the manual input of operating parameters can be partially or even completely eliminated. In addition, any configuration errors can be reliably avoided. This ensures a consistently high quality of maintenance.
Another advantageous aspect of the method provided is that there is no need to provide complex databases for different bioreactors and maintenance systems, which previously had to be created, stored, and maintained manually. Instead, it is now possible to dynamically generate a maintenance program as needed to obtain a maintenance program that is optimally matched to the current characteristics data. If necessary, this process can be repeated whenever a maintenance program is required or whenever there is a change in the system characteristics data and/or reactor characteristics data. Thus, it is not necessary for the maintenance system to be configured by a static maintenance program to operate a maintenance system in a fixed and permanent manner. Instead, a maintenance program can be generated immediately before maintenance is carried out and then used as the basis for maintenance.
It is of particular advantage if the reactor characteristics data is received from the bioreactor. In this way, it can be ensured that the maintenance program generated actually “fits” the respective bioreactor, i.e., is adapted to the respective bioreactor. This also provides the possibility of operating the maintenance system on different bioreactors without any problems, without having to reconfigure the maintenance system manually each time the bioreactor is changed. Instead, a new maintenance program can be generated, for example, automatically in each case and used as the basis for operating the maintenance system. In particular, this can be done completely automatically. If fully automatic generation of the maintenance program is not required or desired, additional inputs, such as manual inputs by the operating personnel, can be taken into account when generating the maintenance program. However, the operating effort can be considerably reduced compared to a conventional configuration of a maintenance system.
System characteristics data generally represent operationally relevant characteristics of the maintenance system. This can include both physical dimensions of the maintenance system and electronic operating information. Correspondingly, the reactor characteristics data represent general operation-relevant characteristics of the bioreactor, which can include both physical dimensions of the bioreactor and electronic operating information of the bioreactor.
Embodiments of the invention are defined in the dependent claims, the description, and the figures.
The system characteristics data and/or the reactor characteristics data can be stored at least partially in a respective digital library in which the characteristics data are structured in a predetermined format. The respective library can in principle be stored at any location. Preferably, however, it is stored close to or directly at the underlying element in order to be able to generate the maintenance program, if desired, as autonomously as possible, i.e., independently of lengthy data transmission paths. For example, a system characteristics data library may be stored at the maintenance system and a reactor characteristics data library may be stored at the bioreactor. However, it is also possible for both libraries to be stored at a common location, e.g., at the maintenance system.
As a “universal library,” a reactor characteristics data library can include the characteristics data for different types of bioreactors, so that the characteristics data required for a particular bioreactor type are always available. In order to keep such a library concise, the library can contain only those characteristics data that are relevant for maintenance operation.
According to one embodiment, the maintenance system has at least one system container that is connected to a plurality of system lines of the maintenance system, wherein the system characteristics data represent at least one predefined system characteristic value of the system container and/or the system lines. The system characteristics data can thus comprise characteristic values concerning physical dimensions of the maintenance system which are relevant for the operation of the maintenance system, in particular, fluid-carrying parts of the maintenance system. In this way, possible filling volumes and flow rates can be directly specified or calculated. Generally, such characteristic values are regarded as invariable in the sense of a fixed specification of the maintenance system. However, it is conceivable that, for example, a system line is replaced by another system line with a larger diameter and the relevant system characteristics data are changed accordingly. Preferably, the system characteristics data are stored at the maintenance system, e.g., in a non-volatile memory of the maintenance system. However, it is also possible to store the system characteristics data on an external memory, such as on a central server, and to retrieve it from there when the maintenance program is generated. Other storage locations, e.g., on a mobile operating device of the maintenance system, are also conceivable.
According to a further embodiment, the bioreactor has at least one reactor vessel which is connected to a plurality of reactor lines of the bioreactor, wherein the reactor characteristics data represent at least one predefined reactor characteristic value of the reactor vessel and/or the reactor lines, in particular, wherein the reactor characteristics data comprise reactor identification data which are uniquely assigned to the reactor characteristic value. The reactor identification data can be designed analogously to the system identification data, i.e., comprise characteristic values which concern physical dimensions of the bioreactor which are relevant for the maintenance of the bioreactor, in particular fluid-carrying parts of the bioreactor. In this way, possible filling volumes and flow rates can be directly specified or calculated. Generally, such characteristic values are regarded as invariable, just as in the case of the maintenance system. However, it is also conceivable that the dimensions of parts of the bioreactor change, e.g., in the course of a repair. The maintenance characteristics data can then be modified accordingly. Preferably, the reactor characteristics data are stored on the bioreactor, for example, in a non-volatile memory that is connectable to the communication interface of the bioreactor. However, it is also possible to partially store the reactor characteristics data on an external memory, such as a central server, and retrieve it from there when the maintenance program is generated. Storage locations other than those mentioned may also be suitable, depending on the design of the process. In general, the system and maintenance characteristic data are available in digital form and can accordingly be stored and updated flexibly.
As mentioned, the reactor characteristics data can include reactor identification data that is uniquely assigned to the reactor characteristic value. This allows that in case of a large number of different reactor characteristic values, which should not be stored at the bioreactor, e.g., for storage capacity reasons, and are instead stored at another location, e.g., at the maintenance system, with the reactor characteristic values being assigned to the reactor identification data. In this way, the reactor characteristic values need not be transferred from the bioreactor to the maintenance system. Instead, it is sufficient to transfer only the reactor identification data, wherein because of the unique association, the characteristic values can be immediately identified and taken into account in generating the maintenance program. In other words, the reactor characteristics data can have several components stored in different locations to make the procedure particularly efficient and safe.
According to one embodiment, the system characteristics data represent at least one system operating state value and/or the reactor characteristics data represent at least one reactor operating state value, in particular, wherein the system operating state value and/or the reactor operating state value indicates a deviation from a predefined operating state. A system operating state value indicates an operating condition of the maintenance facility that can be detected, for example, by a sensor system of the maintenance system. Examples of system operating state values are a current fill level of a system vessel, a temperature, a meter value or a pressure value. Correspondingly, a reactor operating state value indicates an operating status of the bioreactor.
In addition to operating state values that change regularly during operation, operating state values can also be included that usually have a predefined value or should at least lie within a predefined range. For example, the function of valves can be monitored and a deviation from a predefined operating behavior can be detected (e.g., monitoring of valve end positions, adjustment duration, or force required for adjustment). In this way, critical signs of wear or maintenance requirements can be detected in the sense of a system diagnosis in order to avoid a malfunction, especially in field operation conditions. This information can already be taken into account when generating the maintenance program, so that maintenance is adapted accordingly and/or the operator is informed about this.
Another example of a reactor operating state value is the heating rate achieved in a sanitizing unit. If the heating rate falls below a predefined threshold value or an unusual change over time is detected, excessive contamination or wear of the sanitizing unit can be concluded and suitable countermeasures can be taken, e.g., by extending the maintenance program compared with basic maintenance.
Generally, operating state values for the reactor and/or maintenance system may include condition values that monitor a maintenance success. For example, a reactor operating state value may indicate a throughput rate through the bioreactor achieved during a throughput test. If the throughput rate is insufficient, an additional cleaning may be initiated or another appropriate action, such as replacement of parts, may be taken.
It should, therefore, be understood that the maintenance program can be generated dynamically as a function of relevant operating characteristics and can accordingly be optimally adapted to the technical conditions. This makes maintenance highly efficient and reliable. Furthermore, it is possible that during the execution of the generated maintenance program, the system characteristics data and/or the reactor characteristics data are updated and form the basis for a further and renewed generation of the maintenance program. In particular, the maintenance program can be designed in such a way that certain parts of the system characteristics data and/or reactor characteristics data, e.g., certain operating state values, are recorded in order to take them into account in a further and renewed generation of the maintenance program. The method for generating the maintenance program can thus be designed recursively.
According to an embodiment, the generation of the maintenance program comprises an adaptation of a predefined maintenance program at least on the basis of the system characteristics data and the reactor characteristics data. The generation of the maintenance program can thus be made particularly efficient and safe, e.g., by only modifying those elements of a basic program which actually require adaptation depending on the currently recorded data. The predefined maintenance program can also be a maintenance program already generated with the method described herein.
According to an embodiment, the system characteristics data and/or the reactor characteristics data are updated, wherein the maintenance program is adapted or completely newly generated on the basis of the updated system characteristics data and/or reactor characteristics data. Modifications in the data can thus be dynamically taken into account when generating the maintenance program. It is to be understood that an adaptation of an existing maintenance program can be regarded as a generation of a maintenance program.
According to an embodiment, the system characteristics data and/or the reactor characteristics data are updated automatically on an event-related basis and/or at time intervals. For example, the data can be updated at regular time intervals to ensure that the maintenance program is always based on an up-to-date database and thus optimum maintenance results can be guaranteed. Depending on the updated data, it can first be checked whether an adjustment or a complete new generation of the maintenance program is required. This can also be done for event-related updates, e.g., in the case of an error message that calls maintenance operation into question. Unnecessary modification to the maintenance program can thus be avoided, while nevertheless necessary modifications can be identified and carried out as quickly as possible.
According to one embodiment, the maintenance program has a plurality of operating parameters that determine a maintenance program sequence, wherein generating the maintenance program comprises applying at least one calculation rule, and wherein the at least one calculation rule represents a predefined relation between at least the plurality of operating parameters, the system characteristics data, and the reactor characteristics data. For example, a maintenance program sequence may include a plurality of maintenance steps in which fluids, such as freshwater and acid, are pumped from the maintenance system into the bioreactor to clean the bioreactor. This usually also requires the resulting dirty water to be extracted. The necessary pumping and suction times can be calculated directly from the relevant characteristic values of the maintenance system and the bioreactor by a calculation rule. For example, the calculation rule may comprise one or more algebraic expressions specifying a mathematical relationship between the pumping and suction times on the one hand, and the constraints specified by the characteristic values on the other hand. The calculation rule can also be based on a machine learning model and thus also have a high degree of complexity compared to simple formulas. Manual and, therefore, potentially error-prone calculation and definition of operating parameters based on individual databases and empirical knowledge can be avoided in this way.
According to an embodiment, the method further comprises a collection of maintenance characteristics data for the maintenance program, wherein the maintenance program is generated based on the maintenance characteristics data. Maintenance characteristics data may be data directly relating to the desired or required maintenance, in particular, maintenance intervals or a cleaning program, e.g., a mechanical or chemical cleaning. In principle, the maintenance characteristics data can be included in a similar way as the system characteristics data and the reactor characteristics data. For example, the calculation rule may represent a predefined relation between at least the plurality of operating parameters, the system characteristics data, the reactor characteristics data, and the maintenance characteristics data. Further, the maintenance characteristics data may be updated in at least a similar manner as the system characteristics data and the reactor characteristics data.
The maintenance characteristics data can include a maintenance history of the bioreactor, wherein the maintenance history is preferably part of the reactor characteristics data. From the maintenance history, a necessary maintenance requirement can be determined directly, in the sense of a digital service booklet, so that this information can advantageously be considered in the generation of the maintenance program adapted with respect to the maintenance history. It is particularly advantageous if the maintenance history does not have to be administered in a separate database, for example, but is transferred as part of the reactor characteristics data, e.g., from the bioreactor to the electronic data processing means used to generate the maintenance program. Any inconsistencies between reactor characteristics data and maintenance characteristics data can thus be avoided. Preferably, the maintenance characteristics data are updated after or during the execution of a maintenance program, so that the performed maintenance can be automatically taken into account during a subsequent maintenance and generation of a maintenance program.
According to an embodiment, the maintenance system has a user interface, wherein the determination of the system characteristics data and/or the reactor characteristics data and/or maintenance characteristics data for the maintenance program comprises a determination of input data that are entered by a user of the maintenance system at the user interface. In this way, the generation of the maintenance program by an operator of the maintenance system can be supported. Although in general a fully automatic generation of the maintenance program is desired and may be adequate, in many cases it is nevertheless useful that individual aspects of the generation of the maintenance program are dependent on an input by the operator. The operator is thus granted a certain degree of control over the maintenance program, for example, with regard to the cleaning procedure to be used. For example, it is possible that the maintenance characteristics data and reactor characteristics data may result in a maintenance requirement that can be addressed by different types of cleaning programs or a sequence of cleaning steps to be determined. In such a case, as an alternative to automatic selection, the operating personnel themselves can decide which cleaning program type is to be carried out. The operator can then enter this information via the user interface. The user interface may comprise, for example, a graphical user interface provided on the maintenance system. However, the user interface can also be provided on a mobile operating device, such as a tablet or the like.
The determination of input data can also be exploited to minimize the effort required to generate the maintenance program. For example, data can be recorded separately that can generally be entered relatively easily by an operator, but whose fully automatic calculation is time-consuming and would require considerable additional information. An example of such data is the selection of a characteristics diagram or map to be used, which can form the basis for the generation of the maintenance program. The determination of input data is also useful if certain data only deviates from a standard case in exceptional cases and the exceptional case can be taken into account by the operating personnel without further ado. Determining input data can also take the form of queries in which an operator must confirm certain data, for example, for security reasons. For example, in the case of an unusual operating state value, it can be queried whether the maintenance program should still be generated. In this way, incorrect maintenance can be effectively avoided.
According to an embodiment, a cleaning program for cleaning the bioreactor is part of the maintenance program. The cleaning program may include, for example, mechanical and/or or chemical cleaning, as explained in more detail below. Alternatively or in addition to a cleaning program, a test program for testing components of the bioreactor may be part of the maintenance program. For example, a test program may include testing valves of the bioreactor. Further, a sanitizing unit may be tested by determining a heating rate. If the heating rate does not meet a predefined test condition, e.g., is below a threshold, a negative test result may be generated.
It is generally possible that the maintenance program contains control commands for the bioreactor. Corresponding control commands can be received, for example, via the communication interface on the bioreactor and processed by the bioreactor during the execution of the maintenance program. In this way, the bioreactor can actively participate in the maintenance. This enables smart maintenance concepts, e.g., to perform maintenance faster and more efficiently than before. For example, the maintenance program can have a command to operate a sanitizing unit of the bioreactor to heat an acid introduced for chemical cleaning of the bioreactor and in this way reduce the exposure time of the acid. The maintenance time can thus be reduced.
The generated maintenance program can provide that a report is generated containing a maintenance result. This ensures that the operating personnel is informed about the maintenance success, but also about any maintenance problems. Thus, even when the maintenance system is operated automatically by the maintenance program, the operator maintains control and a high quality of maintenance is still ensured. For example, an operator can perform a re-cleaning or a repair of the bioreactor if the report gives reason to do so. The maintenance program may also provide for the generation of interim reports to monitor the execution of the maintenance program.
According to an embodiment, the electronic data processing means is formed by an electronic data processing unit of the maintenance system, wherein the data processing unit is connected to at least a first interface and a second interface of the maintenance system, wherein the system characteristics data is received at least partially at the first interface, and wherein the reactor characteristics data is received at least partially at the second interface from the communication interface of the bioreactor. The data processing unit may be formed by a control unit of the maintenance system. Thus, the processing resources of the maintenance system can be kept lean overall so that cost increases can be avoided despite the functionality provided by the method.
The first interface and the communication interface may be formed as wired interfaces. Alternatively, the interfaces may include wireless units to enable a wireless communication link between the bioreactor and the maintenance system. In this way, reactor characteristics data may be received directly from the maintenance system. However, it is also conceivable that the reactor characteristics data may be received, for example, via a central server from the communication interface at the first interface. Thus, the reactor characteristics data do not have to be transmitted directly to the maintenance facility.
The second interface is preferably an interface that can be connected to an internal memory of the maintenance system, with the system characteristics data being stored in the internal memory. However, it is also possible for the second interface to have an interface for connecting the maintenance system to an external memory in which the system characteristics data are stored. The external memory can, for example, be part of a central server that can be connected to the second interface. For this purpose, the second interface can have a wireless unit, e.g., a mobile radio interface, so that the maintenance system can be connected to the central server via a mobile internet connection and the system characteristics data can be transmitted to the maintenance system quickly and reliably.
Local network connections are also conceivable. For example, the second interface can be connected via a wireless or wired local network to a mobile operating device in which the system characteristics data are stored. In principle, suitable connection types can be considered for a wireless connection, e.g., WLAN, Bluetooth, Zigbee, but also mobile radio standards such as 3G, 4G, and 5G. Wired connections can, for example, be designed according to a bus standard or the Ethernet standard. However, other forms of communication can also be considered for a wired connection. For example, a transmission protocol can be used that is based on two signal states according to the ASCII code (American Standard Code for Information Exchange) (e.g., “high” and “low”). In this way, the transmission can be designed to be particularly robust against external electromagnetic influences. Furthermore, one or more modems can be used to establish connections between the interfaces, e.g., a wired modem or a radio modem to establish a wireless connection.
It is possible to connect the maintenance system and the bioreactor via an ad hoc network. The establishment of a communication link can thus be carried out particularly conveniently, so that the maintenance of the bioreactor is further simplified.
The invention further relates to an apparatus for generating a maintenance program for the operation of a maintenance system on a bioreactor, in particular, a bioreactor of a vehicle for transporting persons, the apparatus comprising electronic data processing means associated with the maintenance system for carrying out the method according to any one of the preceding claims.
Apparatus features described in connection with method features may be realized individually or also jointly on the apparatus. For example, the apparatus may be formed by the maintenance system and may, in particular, comprise the aforementioned first and second interfaces. Likewise, the data processing means may be formed by a data processing unit of the maintenance system. However, it is also possible that the data processing means is formed at a central server and the generation of the maintenance program is not performed at the maintenance system but remotely. After generation, the maintenance program can be transferred to the maintenance system and executed there in order to operate the maintenance system.
The invention further relates to a computer program comprising instructions which, when the computer program is executed by an electronic data processing means, causes the electronic data processing means to execute the method according to any of the embodiments described above. Also, the invention relates to a storage medium in which the computer program is stored.
The invention further relates to a method of operating a maintenance system on a bioreactor, in particular, a bioreactor of a vehicle for transporting people, the method comprising operating the maintenance system by a maintenance program generated by a method according to any of the embodiments described above.
Features described in connection with embodiments of the method for generating the maintenance program may also be realized in the method for operating the maintenance system, in particular, each embodiment separately or in combinations of embodiments.
The invention further relates to a maintenance system for maintaining a bioreactor, in particular, a bioreactor of a vehicle for transporting people, wherein the maintenance system comprises an interface for transmitting data between the maintenance system and the bioreactor.
Features described in connection with embodiments of the method for generating the maintenance program may also be realized in the maintenance system, in particular, each embodiment separately or in combinations of embodiments. In particular, the maintenance system may include an interface, for example, the second interface described previously, for receiving reactor characteristics data from the bioreactor. Further, the same interface may be provided for sending control data to the bioreactor, although alternatively a separate interface may be provided for this purpose.
The invention further relates to a bioreactor having a communication interface for transmitting reactor characteristics data to a maintenance system, as more particularly described above. Further, a system comprising such a bioreactor and a maintenance system is disclosed. The maintenance system may be configured according to any of the described embodiments.
Embodiments of the invention are now described below with reference to the drawings. These are not necessarily intended to show the embodiments to scale; rather, where useful for explanation, the drawings are in schematized and/or slightly distorted form. With regard to additions to the gauges directly recognizable from the drawings, reference is made to the relevant prior art. It should be borne in mind that a wide variety of modifications and changes concerning the shape and detail of an embodiment can be made without departing from the general idea of the invention. The features of the invention disclosed in the description, in the drawings as well as in the claims may be essential for the further development of the invention both individually and in any combination. In addition, all combinations of at least two of the features disclosed in the description, the drawings and/or the claims fall within the scope of the invention. The general idea of the invention is not limited to the exact form or detail of the preferred embodiments shown and described below, or limited to any subject matter that would be limited as compared to the subject matter claimed in the claims. In the case of specified design ranges, values within the specified limits are also intended to be disclosed as limiting values and to be capable of being used and claimed as desired. For simplicity, identical reference signs are used below for identical or similar parts or parts with identical or similar function.
Further advantages, features, and aspects of the invention will be apparent from the following description and from the drawings. The drawings show in:
A maintenance system 1 can be designed as a mobile maintenance system, as shown in
The maintenance system 1 has connections via which it can be connected to the bioreactor 2. For example, in order to draw off liquid from the bioreactor 2, the maintenance system 1 has a first suction connection 20, which can be connected to the 1-inch connection 11 of the liquid tank 5 of the bioreactor 2 via a first suction line 22. Furthermore, the maintenance system 1 has a second suction connection 24, which can be connected to the 2-inch hose 9 of the bioreactor 2 via a second suction line 26, in order to suction or draw off liquid from the bioreactor 2, more specifically the solids tank 4, via the latter, in order to remove filter cake formed there. However, liquid can also be added to the bioreactor 2 via the 2-inch hose 9 for cleaning purposes, as will be described in more detail below The maintenance system 1 also has a high-pressure connection 28, which can be connected to the cleaning nozzle 10 via a high-pressure hose 30, and an electronic control connection 32, which can be connected to the control 12 of the bioreactor 2 via a signal line 34.
The maintenance system 1 further has a disposal connection 36, via which the maintenance system 1 can be connected to an external tank 38 or a sewer system, which is connected to an external vacuum source 39, for extracting liquid from the maintenance system 1. On the input side, the maintenance system 1 has a voltage connection 40 and a fresh water connection 42.
Inside the maintenance system 1 (
A warning light 56 is optionally provided on a top surface of the maintenance system 1, which is adapted to emit light in different colors for indicating a status, a fault, or the like of the maintenance system 1.
In
The pump 46 has a first pump port 64 and a second pump port 66, and the pump 46 is preferably configured as a rotary pump and can pump fluid from the first pump port 64 to the second pump port 66 as well as vice versa from the second pump port 66 to the first pump port 64.
A first line L1 extends from the first suction connection 20 in the direction of the first pump port 64. The first line L1 is connected to a first valve BV9, which in turn is connected to a second line L2. The first valve BV9 is designed as an electrically switchable ball valve and can be controlled by the electronic control unit 44. Other types of valves, such as switching valves, are also preferred. Now, it is important in the context of the invention that some of the valves are electrically switchable by the electronic control unit 44. A ball valve has the advantage that the flow through the valve is continuously adjustable. Moreover, in the embodiment shown, a first manual valve HH1 is placed in the first line L1, which allows manual opening and closing of the first line L1. A first capacitive sensor VF1 is also provided between the first valve BV9 and the first manual valve HH1, which senses the presence of fluid in the first line L1 and provides a signal representing the presence of fluid in the first line L1 to the electronic control unit 44.
Here, the second valve BV10 is connected to the first pump connection 64, more specifically to a first pump line PL1 that originates from the first pump connection 64. With reference to
The second suction connection 24 is connected to a third line L3, which is connected to a fourth line L4 via a third valve BV8. Again, a second manual valve HH2 is placed in the third line L3, which allows manual opening and closing of the third line L3. A second capacitive sensor VF2 is placed between the second manual valve HH2 and the third valve BV8, which also detects the presence of fluid there and provides a corresponding signal representing the presence of fluid to the electronic control unit 44. A first pressure sensor PT1 is also provided in the first line L1 and a second pressure sensor PT2 is provided in the third line L3, which detect pressure in the first and third lines L1, L3 and provide corresponding first and second pressure signals to the electronic control unit 44. The fourth line L4 is connected to the second pumping port 66 via a fourth valve BV5, more specifically to a second pumping line PL2. The second pump line PL2 connects the second pump port 66 to the fourth valve BV5.
According to the embodiment shown here, a bypass is also provided between the second line L2 and the fourth line L4, namely in the form of a bypass line BL which can be closed by a fifth valve BV7. The bypass line BL is used to allow not only the first suction port 24 to be connectable to the first pump port 64 via the first line L1 and the second line L2, but the first suction port 20 is also connectable to the second pump port 66 via the first line L1, the bypass line BL and the fourth line L4. In a corresponding manner, the second suction port 24 is also connectable to the second pump port 66 not only via the third and fourth lines L3, L4, but also via the third line L3, the bypass line BL, and the second line L2 and the first pump line PL1. Depending on the directions in which liquids should be pumped, this is advantageous.
If, for example, liquid is extracted from the bioreactor 2 in a first cleaning step, this is done via the second suction connection 24. For this purpose, the second manual valve HH2 is to be opened, at the same time the electronic control unit opens the third valve BV8 and the fourth valve BV4 and the pump conveys the extracted liquid from the second pump port 66 to the first pump port 64 in the first pump line PL1. The second valve BV10 is closed and liquid flows through the first pump line PL1 towards system D. In system D, the collection tank 50 is connected to the first pump line PL1 via a first collection tank valve BV82 and the acid tank 52 is connected to the first pump line PL1 via a first acid tank valve 85. Thus, in order to convey the extracted liquid from the second suction connection 24 into the collection tank 50, the electronic control unit 44 also opens the first collection tank valve 82. If liquid is now additionally to be extracted from the liquid tank 5 of the bioreactor 2 via the first suction connection 20, the first manual valve HH1 must be opened. The electronic control unit 44 then opens the first valve BV9, the fifth valve BV7 and the fourth valve BVS. In this way, the first suction connection 20 is connected to the second pump port 66. The pump 46 can then, in turn, pump from the second pumping port 66 to the first pumping port 64, thereby delivering the fluid extracted via the first suction port 20 to the collection tank 50 via the first collection tank valve 82.
The collection tank 5 is emptied into the disposal tank 38 or into the sewer system via a third manual valve HH50, which connects the collection tank 50 to the disposal connection 36.
In system D, in particular, differences exist between the mobile maintenance system 1 shown here and a stationary maintenance system. For example, a separate additional pump may be provided to empty the collection tank 50 and the acid tank 52, preferably in the form of a double pump. In addition, a further pump is preferably provided, again in the form of a double pump, for filling the acid tank 52 with acid and for filling the acid from the acid tank into the respective connected bioreactor. By means of the further pump, in this case, circulation of the liquid through the bioreactor can also be carried out. In addition, a stationary system can have an additional connection for providing freshwater for a catering service in the railcar, as well as another additional connection for providing freshwater for hand washing and/or toilet flushing. A branch line for this additional connection preferably branches off directly from the freshwater connection 42, so that no contamination can take place here.
Also connected to the fourth line L4 is a sixth valve BV6, which connects the fourth line L4 to a first measuring line ML1. The first measuring line ML1 leads on the one hand to the measuring unit 60, and on the other hand to an eighth valve BV1, which is connected to a first freshwater line FL1 via a first flow sensor FT1. The first fresh water line FL1 is connected to the freshwater connection 42 via a check valve 68 and thus receives freshwater from the freshwater connection 42. If, for example, freshwater is to be fed into the filter basket 8 of the bioreactor 2 via the second suction connection 24, the eighth valve BV1, the sixth valve BV6 and the third valve BV8 must then be opened for this purpose. Freshwater is already provided under a certain pressure via the freshwater connection 42, and can thus be fed directly into the bioreactor 2 with sufficient pressure. However, if freshwater under increased pressure is to be supplied to the cleaning nozzle 10 via the flushing connection 28, a ninth valve MV1, which is designed here as a solenoid valve, must first be opened for this purpose. The ninth valve MV1 connects the first freshwater line FL1 downstream of the first flow sensor FT1 to the high-pressure pump 48, which can then provide freshwater under high pressure to the flushing connection 28. The ninth valve MV1 and the high pressure pump 48 are also controlled by the electronic control unit 44.
The freshwater port 42 is further connected to the acid dosing unit 62 via a second freshwater line FL2. The acid dosing unit 62 includes a plurality of acid canister ports 70, and a plurality of base canister ports 80. The acid canister ports 70 are connected to acid canisters 72, and the base canister ports 80 are connected to base canisters 82. The acid and base canisters 72, 82 can be interchanged and are stored, for example, at the lower portion of the maintenance system 1. The second freshwater line FL2 leads to a tenth valve BV78, and from there to a second flow sensor FT60. Downstream of the second flow sensor FT60, a third pressure sensor PT60 and a first pH sensor QT60 are provided. The second flow sensor FT60, the third pressure sensor PT60, and the first pH sensor QT60 can be used to detect values of the fluid present in the first dosing line DL1. Downstream of the first pH sensor QT60, the first dosing line DL1 branches into an acid line S1, a second dosing line DL2, and a first base line B1. The first acid line S1 leads to an acid doser 74, which is designed here as an acid ejector and, in addition to liquid from the first dosing line DL1 or first acid line S1, also receives undiluted acid via a second acid line S2, which is connected to the acid canister connections 70. An eleventh valve MV71, which is designed as a solenoid valve, is inserted into the second acid line S2. It serves to seal off the acid canister connections 70 from the second acid line S2. Downstream of the acid doser 74, a twelfth valve BV60 is provided, which is again designed as a ball valve and is again controlled by the electronic control unit 44. The twelfth valve BV60 connects the acid doser 74 to a third acid line S3, which leads to a mixer 90. The mixer 90 may comprise, for example, a static mixer having a mixing element.
On the other side, the first base line B1 connects the second flow line DL2 to a base dosing unit 84, which is designed here as a base ejector. The base dosing unit 84 receives not only liquid via the first base line B1, but also undiluted base via a second base line B2. A thirteenth valve MV73 is placed in the second base line B2, which is formed as a solenoid valve, and is controlled by the electronic control unit 44. The thirteenth valve MV73 serves to seal off the base canister connections 80 from the second base line B2 or the base doser 84. Downstream of the base doser 84, a fourteenth valve BV62 is provided, which is again a ball valve and is controlled by the electronic control unit 44. The fourteenth valve BV62 connects the base doser 84 to a third base line B3, which also opens into the mixer 90. Thus, a fluid having a specific pH can be generated in the mixer 90 via this arrangement. Downstream of the mixer 90, the mixer 90 opens into a third dosing line DL3 in which a second pH sensor QT61 is inserted to provide a second pH signal to the electronic control unit 44. The third dosing line DL3 branches into a fourth dosing line DL4, which leads to the acid tank 52 or collection tank 55, and a fifth dosing line DL5, which leads back to system A. The fourth dosing line DL4 is connected to a second acid tank valve BV83 and a second collection tank valve BV80, so that liquid from the fourth dosing line DL4 can be selectively fed to the acid tank 52 or collection tank 50 via the second acid tank valve BV83 and the second collection tank valve BV80. This is particularly important if an aqueous acid solution is to be generated in the acid tank 52. To this end, the electronic control unit 44 controls the tenth valve BV78, the eleventh valve MV71, the twelfth valve BV60, the fourteenth valve BV62, and the thirteenth valve MV73 such that a liquid having a predetermined desired pH can be provided in the fourth dosing line DL2 and thus enter the acid tank 52.
Aqueous acid solution is used, in particular, to chemically clean the bioreactor 2 for removing lime deposits on it. For this purpose, aqueous acid solution must be fed from the acid tank 52 to the first and/or second suction ports 20, 24. This is effected by the pump 46, which is connected to the acid tank 52 in an appropriate manner. For example, if aqueous acid solution is to be provided to the first suction port 20, the electronic control unit 44 opens the first acid tank valve BV85, the fourth valve BV5, the fifth valve BV7, and the first valve BV9. Aqueous acid solution is then provided via the first pump line PL1, from the first pump port 64 to the second pump port 66 and via said valves to the first suction port 20. In a corresponding manner, aqueous acid solution can also be provided at the second suction port 24, in which case, in deviation from the aforementioned, the fifth and first valves BV7, BV9 do not have to be opened, but instead only the third valve BV3.
If an aqueous acid solution has been used to clean the bioreactor 2, it is also necessary to extract it again from the bioreactor 2. This is done via the first suction connection 20. If an aqueous acid solution is suctioned out of the bioreactor 2 via the suction connection 20, the first valve BV9, the fifth valve BV7, the fourth valve BV5 and the first acid tank valve BV85 are opened for this purpose. The pump 46 then pumps the aqueous acid solution from the second pump port 66 to the first pump port 64, and consequently into the acid tank 52.
If the aqueous acid solution in the acid tank 52 is to be neutralized, the electronic control unit 44 controls the acid dosing unit 62 accordingly to provide a liquid suitable for neutralizing the aqueous acid solution in the acid tank 52. It is also possible to achieve flow-through neutralization. For this purpose, aqueous acid solution is drawn from the acid tank 52 via the first acid tank valve 85 by means of the pump 46, pumped from the first pumping port 64 to the second pumping port 66, and from there via a return valve BV3 connecting the second pumping line PL2 or the second pumping port 66 to the acid metering unit 62. More specifically, a return line RL leads from the return valve BV3 to the second fresh water line FL2 and opens into it downstream of the tenth valve BV78 but upstream of the first flow meter 60. By means of the first pH sensor QT60, the pH of the aqueous acid solution thus recycled from the acid tank 52 can then be determined and the valves BV60, BV62 and a restriction BV61 can be controlled so that sufficient base is added to the aqueous acid solution provided through the recycle line RL3 to neutralize it. After the solution has been neutralized in the acid tank 52, it can be conveyed to the collection tank 50 by means of the pump 46.
To improve cleaning of the bioreactor 2 with aqueous acid solution, air can also be introduced into the aqueous acid solution via the first suction connection 20 in the form of bubbles. For this purpose, a compressor 92 is provided, which is connected to the first line L1 via a compressor line 93 and a compressor valve MV2, and can thus feed compressed air into the first line L1. The compressor 92 and the first compressor valve MV2 can also be controlled by the electronic control unit 44.
The measuring unit 60 is constructed and connected to the further elements as follows: The measuring unit 60 comprises a measuring chamber 96 with a first port 97, a second port 98 and a third port 44. The first port 97 is connected to the second pump line PL2 via a first measuring valve BV41, in particular, via a second measuring line ML2. The second port 98 is connected to the first measuring line ML1 via a second measuring valve BV40, and the third port 44 is also connected to the first measuring line ML1 via a third measuring valve BV43. A level sensor LT40 is further provided at the measuring chamber 96, which is connected to the electronic control unit 44 and can provide a measuring level signal thereto. The measuring unit 60 is used to test the permeability of the bioreactor 2 after cleaning has been performed. For this purpose, a predetermined volume of freshwater is first metered in the measuring chamber 96. This is preferably done by opening the eighth valve BV1 and the second measuring valve BV40. In this way, freshwater can flow through the second port 98 into the measuring chamber 96 until a predetermined volume is reached, which is determined by means of the measuring level signal.
After the predetermined volume has been metered in the measuring chamber 96, it can be supplied to the bioreactor 2 via the second suction port 24. For this purpose, the first measuring valve BV41 is opened, the liquid is pumped from the second pumping port 66 to the first pumping port 64, then further via the second valve BV10, the bypass line BL, the fifth valve BV7 as well as the third valve BV8 to the second suction port 24. Subsequently, a predetermined time is waited until the liquid has passed through the bioreactor 2. Subsequently, the liquid is extracted from the liquid tank 5 via the first suction connection 20 by opening the first valve BV9 and the second valve BV10, the liquid is pumped from the first pumping port 64 to the second pumping port 66 and then introduced into the measuring chamber 96 via the fourth valve BV5, the sixth valve BV6, and the third measuring valve BV43. There, the extracted fluid is measured again. If the volume difference between the supplied liquid and the extracted liquid does not exceed a predetermined threshold, the cleaning is okay. If the volume difference exceeds a predetermined threshold, the cleaning is not okay and a corresponding warning signal can be output, for example, via the warning light 56 and/or the human-machine interface 54. The comparison of whether or not the volume difference exceeds the predetermined threshold is preferably performed by the electronic control unit 44.
Referring now to
In step S10, freshwater is first introduced into the bioreactor 2 from the freshwater connection 42 via the second suction connection 24. For this purpose, the electronic control unit 44 switches the corresponding valves and controls the pump 46, as basically described above. In this first step S10, preferably about 50 liters of water are introduced into the bioreactor 2. This should take about 1 minute. In step S11, liquid is then extracted from the bioreactor 2 via the second suction connection 24 and pumped into the collection tank 50. For this purpose, the electronic control unit 44 also controls the corresponding valves and the pump 46. This is preferably carried out until the second capacitive sensor VF2 detects that there is no more liquid in the line L3. Step S12 is then optional and in this step liquid is extracted from the bioreactor via the first suction connection 20. This is not mandatory, but can be implemented to clean the bioreactor of this liquid. Subsequently, in step S13, liquid, preferably freshwater, is again preferably added to the bioreactor 2 via the second suction port 24. Liquid can also be added to the bioreactor 2 via the first suction port 20 in step S15. This both serves to flush up solids in the bioreactor 2. In step S16, additional mechanical cleaning is then preferably carried out by providing freshwater under high pressure via the flushing connection 28. For this purpose, the electronic control unit 44 controls the corresponding valves, namely, in particular, the ninth valve MV1 as well as the high-pressure pump 48. During this flushing with high pressure, preferably only 40% of the bioreactor volume is filled with water. Depending on the bioreactor 2, this can correspond to a volume of approximately 70 to 100 liters.
In step S17, liquid is then again extracted from the bioreactor 2 via the second suction connection 24, and in step S18, liquid is also extracted via the first suction connection 20. In both, step S17 and step S18, extraction or suctioning preferably continues until the first and second capacitive sensors VF1, VF2 detect that there is no liquid left in the first and third lines L1, L3, respectively. Steps S19 to S23 are then preferably repetitions of steps S14 to S18 and may be repeated as many times as necessary to achieve sufficient cleaning. However, it may be envisaged that higher filling levels of the bioreactor 2 are also allowed in the subsequent steps in which liquid is supplied via the flushing connection 28, for example 60, 70 or 80%. It can also be provided that in step S18 as well as in step S23, initially no suction is provided via the first suction connection 20, but that this liquid remains in the bioreactor 2. Only in the last step, before the process is terminated, suction is applied via the first suction connection 20 in order to completely empty the bioreactor 2, in particular, the liquid tank 5.
In step S30, an aqueous acid solution, which has already been provided in the acid tank 52, is supplied to the bioreactor 2 via the first suction connection 20. Subsequently, aqueous acid solution is also supplied to the bioreactor 2 via the second suction connection 24. This can also be done simultaneously with step S30. Alternatively, it is also possible to perform step S31 before step S30. Subsequently, after the aqueous acid solution has been supplied to the bioreactor 2, a waiting time takes place in step S32. This waiting time preferably is at least 5 minutes, preferably it is in the range of 5 minutes to 1 hour, preferably 20 minutes to 30 minutes. This is a sufficient time to clean lime deposits to a large extent. Subsequently or simultaneously, compressed air can also be introduced into the bioreactor 2 by means of the compressor 92 in step S33. The compressor 92 is also controlled by the electronic control unit 44 so that it provides an appropriate signal in step S33. In step S34, a circulation of aqueous acid solution through the bioreactor 2 can be carried out. For this purpose, aqueous acid solution is preferably introduced into the bioreactor 2 via the second suction connection 24 and extracted via the first suction connection 20. For this purpose, the electronic control unit 44 preferably opens the first valve BV9, the second valve BV10, the fourth valve BVS, and the third valve BV3. The pump 46 is driven to pump the fluid from the first pump port 64 to the second pump port 66. In this manner, circulation of the aqueous acid solution through the bioreactor 2 can be effected. During this circulation, air can additionally be introduced into the liquid in the form of bubbles, preferably by means of the compressor 92. The air bubbles in the liquid cause mechanical cleaning of the lines as well.
However, it is also possible to pass the aqueous acid solution that has been extracted from the bioreactor 2 via the first extraction port 20 through the acid dosing unit 62, for example, to dose additional acid.
In step S35, a pause is made and a certain time is waited. This time is again used to allow the aqueous acid solution to act in order to dissolve the lime deposits. It can be of a similar time range as mentioned above, preferably again in the range of 20 to 30 minutes. Then, in step S36, compressed air is preferably again introduced through the first suction connection 22, and in step S37, the aqueous acid solution is circulated in the bioreactor 2. Steps S35 to S37 may then follow this several times, so that several cycles of pause (step S35), introduction of compressed air (S36) and circulation of the aqueous acid solution in the bioreactor 2 (S37) are carried out. For example, five cycles of this can be performed.
Then, in step S38, the aqueous acid solution is extracted from the bioreactor 2 via the first suction connection 20 and supplied to the acid tank 52. This is effected by means of the pump 46 by opening the first valve BV9, the fifth valve BV7, the fourth valve BV5, and the first acid tank valve BV85. The pump 46 then pumps the aqueous acid solution from the second pump port 66 to the first pump port 64 and into the acid tank 52. For flushing the bioreactor of residual acid, freshwater is preferably introduced both at step S39 through the second suction connection 24 and at step S40 through the first suction connection 20. Optionally, freshwater is also introduced through the flushing port 28. This water thus supplied for flushing is preferably subsequently extracted in step S41 and step S42 via the first and second suction connection 20, 24 and pumped into the collection tank 50.
As an alternative to this neutralization in the acid tank 52, neutralization can also be carried out in the bioreactor 2 itself. This can save freshwater for rinsing.
For this purpose, the aqueous acid solution to be neutralized is preferably first suctioned out of the bioreactor 2 into the acid tank 52, preferably via the first suction connection 22. Freshwater is then preferably introduced into the bioreactor 2 in order to flush it a first time. This can be done either via the flushing connection 28 or via the second suction connection 24. The liquid then present in the bioreactor is acidic and must be further neutralized. The liquid can now be extracted via the first suction connection 20, and passed over the acid dosing unit, where it is mixed with base, and fed back into the bioreactor 2. This cycle or cycling can be repeated until a sufficiently neutral pH is achieved. Subsequently, the neutralized liquid can be suctioned out of the bioreactor 2, preferably via the first suction connection 22, and then either fed into the collection tank 50 or directly into a sewer drain. In this way, the bioreactor 2 is flooded with freshwater only once for rinsing, whereas it would have to be rinsed several times if the liquid used for rinsing had to be neutralized in the acid tank 52 after each rinse. This procedure is particularly efficient for mobile maintenance systems that have base canisters containing high doses of base. In stationary systems, on the other hand, diluted base is generally used in order to simplify the tubing or piping between the maintenance system and the bioreactor.
Simultaneously or subsequently, the aqueous acid solution in the acid tank 52 can be neutralized or first tested for its pH content. If the aqueous acid solution is extracted from the bioreactor 2 via the first suction connection 20, it is also conceivable not to pump it directly into the acid tank 52, but by opening the valves BV9, BV10, BV3 to feed it to the acid dosing unit 60 and from there via the second acid tank valve BV83 into the acid tank 52.
The individual steps described herein may also be performed in other sequences, in other combinations, or multiple times. This may be performed based on sensor data or parameters sensed by the electronic control unit 44. For example, the number of repetitions of a circulation of the aqueous acid solution (steps S35 to S37) may be carried out depending on the type of bioreactor read-out from the bioreactor by the electronic control unit 44. Further parameters which may have an influence on this are also the time lapsed since the last cleaning interval, the operating age of the bioreactor, and the like. Such data can be recorded, in particular, as part of the method described below for generating a maintenance program.
With reference to
The control unit 44 includes a processor or the like for executing program code to generate the maintenance program. The generated maintenance program can be executed by the control unit 44, as basically described above, generating and implementing corresponding control commands for operating the maintenance system 2 for this purpose.
As indicated above, the maintenance system 1 is equipped with a human-machine interface 54 adapted to display maintenance information and further to acquire input data that may be entered by an operator not shown.
A wireless interface 97 is provided on the bioreactor 2 for transmitting data, in particular, for sending reactor characteristics data and/or for receiving updates or control data. The wireless interface 97 can be used in addition or alternatively to the interface 95.
With reference to
First, the method is described in a first embodiment. In step S50, reactor characteristics data stored at the bioreactor 2 are transmitted from the bioreactor 2 to the maintenance system 1 via the interface 95 and received there at the interface 96. In an optional step S51, maintenance characteristics data is transmitted to the maintenance system 1 via the same transmission path. The maintenance characteristics data preferably comprises information about maintenance of the bioreactor 2 carried out in the past. In step S52, system characteristics data stored at the maintenance system 2, e.g., in the memory of the control unit 44, is acquired. In step S53, the control unit 44 generates a maintenance program based on the acquired reactor characteristics data, the system characteristics data and the optionally acquired maintenance characteristics data. In step 54, the maintenance program can be executed by the control unit 44, cf.
In the following, the method is described with reference to
Said interfaces 95, 96, 97, and 98 need not all be formed on the bioreactor 2 or the maintenance system 1. Rather, it is possible that only those interfaces are present that are required in the context of one of the described embodiments.
| Number | Date | Country | Kind |
|---|---|---|---|
| 20 2020 104 037.5 | Jul 2020 | DE | national |
| 10 2020 119 924.4 | Jul 2020 | DE | national |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/EP2021/069470 | 7/13/2021 | WO |
