Claims
- 1. An apparatus for performing an activated clotting time test on a sample of blood containing platelets, said apparatus comprising a test cell, and wherein said test cell comprises an anticoagulant, a contact activator, and a predetermined amount of a platelet inactivating agent.
- 2. The apparatus of claim 1, wherein the anticoagulant is heparin.
- 3. The apparatus of claim 2, wherein the amount of heparin in said cell is between about 1 unit and about 4 units per milliliter of blood sample.
- 4. The apparatus of claim 1, wherein the contact activator is a particle having a negatively charged surface.
- 5. The apparatus of claim 3, wherein said particle is kaolin.
- 6. The apparatus of claim 4, wherein the amount of contact activator in said cell is between about 2 percent and about 15 percent.
- 7. The apparatus of claim 4, wherein said particle is diatomaceous earth.
- 8. The apparatus of claim 4, wherein said particle is powdered glass.
- 9. The apparatus of claim 4, wherein said particle is silica.
- 10. The apparatus of claim 1, wherein said platelet inactivating agent is selected from the group consisting of Abciximab, 4-[4-[4-(aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid, hydrochloride trihydrate, and acetylsalicylic acid.
CROSS-REFERENCE TO OTHER APPLICATIONS
This patent application is a divisional application of U.S. patent application Ser. No. 09/225,051, filed Jan. 4, 1999, now U.S. Pat. No. 6,221,672 and entitled “Method for Determining Platelet Inhibitor Response,” which is a continuation-in-part of U.S. patent application Ser. No. 08/640,277, filed Apr. 30, 1996, and entitled “Method For Determining Platelet Inhibitor Response”, now abandoned, all of which are specifically incorporated herein by reference.
US Referenced Citations (24)
Foreign Referenced Citations (2)
Number |
Date |
Country |
0 661 383 |
Dec 1994 |
DE |
WO 9325578 |
Dec 1993 |
WO |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
08/640277 |
Apr 1996 |
US |
Child |
09/225051 |
|
US |