Levitzki, A. and A. Gazit, “Tyrosine Kinase Inhibition: An Approach to Drug Development”, Science 267:1782-1788, Mar. 24, 1995. |
Waters, B. et al., “Protein tyrosine phosphorylation in streptomycetes”, FEMS Microbiology Letters 120: 187-190, 1994. |
Natsume et al., “Calcium Signal Modulators Inhibit Aerila Mycelium Formation in Streptomyces alboniger”, J. Antibiotics 45: 1026-1028, 1992. |
Altschul, S.F., Gish, W., Miller, W., Myers, E. and Lipman, D. 1990, “Basic local alignment tool”, J. Mol. Biol. 215:403-410. |
Av-Gay, Y. and Davies, J. 1997, “Components ofeukaryotic-like protein signaling pathways in Mycobacterium tuberculosis ”, Microbial & Comparative Genomics 2:63-73. |
Georgiou, G., Lin, S-C., and Sharma, M., 1992, Surface-active compounds from microorganisms, Biotechnology, 10: 60-65. |
Gerrard, J., Lloyd, R., Barsby, T., Haden, P., Kelly, M and Anderson, R., 1997, Massetolides A-H, antimycobacterial cyclic depsipeptides produced by two Pseudomonads isolated from marine habitats. J. Nat. Prod., 60:223-229. |
Huncck, S. and Yoshimura, I., 1996 “Identification of lichen substances”, Springer-Verlag, Berlin. |
Lane, D., 1991, 16S/23S rRNA sequencing, p. 115-175 In Stackebrandt, E. and Goodfellow, M., (ed.), “Nucleic acid techniques in bacterial systematics”, John Wiley and Sons, Chichester. |
Lauterwein, M., Oethinger, M., Belsner, K., Peters, T. and Maree, R. 1995, “In vitro activities of the lichen secondary metabolites vulpinic acid, (+)-usnic acid and (−) -usnic acid against acrobic and anacrobic microorganisms”, Antimicrobial Agents and Chemotherapy, 39: 2541-2543. |
Stachelhaus, T., Schneider, A. and Marahiel, M., 1996, “Engineered biosynthesis of peptide antbiotics”, Biochemical Pharmacology, 52: 177-186. |
Toraya, T., Maoka, T., Tsuji, H. and Kobayashi, M., 1995, “Purification and structural determination of an inhibitor of starfish oocyte maturation from a Bacillus species”, Applied and Environmental Micro, 5: 1799-1804. |
Hong et al., “Effects of protein kinase inhibitors on in vitroprotein phosphorylation and cellular differentiation of Streptomyces griseus”, Mol. Gen. Genetics 236: 347-354, 1993. |
Kennelly et al., “Fancy Meeting You Here!, A Fresh Look at ‘Prokaryotic’ Protein Phosphorylation”, J. Bacteriol, 178: 4759-4764, 1996. |
Karin et al., “Transciptional control by protein phosphorylation: signal transmission from cell surface to nucleus”, Current Biology 5: 747-757, 1995. |
Ray, L.B., “Signals and Communication,” Science 268: 183, 1995. |
Casey, P.J., “Protein Lipidation in Cell Signaling”, Science 268: 224-225, 1995. |
Burbulys et al., “Initiation of Sporulation in B. subtilis Is controlled by a Multicomponent Phosphrelay” Cell 64: 545-552. |
Stock et al., “Protein Phosphorylation and Regulation of Adaptive Responses in Bacteria”, Micriobiol. Reviews 53: 450-490, 1989. |
South et al., “Tyrosine Kinase activity in Pseudomonas aeruginosa”, Molecular Microbiol. 12: 903-910, 1994. |
Chow et al., “Protein tyrosine phosphorylation in Mycobacterijm tuberculosis”, FEMS Microbiol. Lett. 124: 203-208, 1990. |
Li et al., “Cloning, Purification and Properties of a Phosphotyrosine Protein Phosphatase from Streptomyces coelicolor A3(2)”, J. Bacteriol. 178: 136-142, 1996. |
Frasch et al., “Tyrosine Kinase in Myxococcus xanthus, a Multicellular Prokaroyte”, preprint of article submitted to J. Bacteriol, 1996. |
Zhang, C-C., “Bacterial Signalling Involving Eukaryotic-type Protein Kinases” Molecular Microbiol. 20:91-5, 1996. |
Zhang et al., “Identification of a Putative Eukaryotic-Like Protein Kinase Family in the Developmental Bacterium Myxococcus xanthus” J. Bacteriol. 174: 5450-5453, 1992. |
Meydan et al., “Inhibition of acute lymphoblastic leukemia by a Jak-2 inhibitor”, Nature 379: 645-648, 1996. |
Leukemia-fighting drug found to work in mice, Vancouver Sun, Feb. 15, 1996, p. A11. |
Clark et al., “Integrins and Signal Transduction: The Road Taken”, Science 268: 233-234, 1995. |
Machyl-Rosen, D., “Localization of Protein Kinases by Anchoring Proteins: A Theme in Signal Transduction”, Science 268, 1995. |
De Franco et al., “Tyrosine Phosphatases and Antibody Response”, Science 268: 263-264, 1995. |