Claims
- 1. A method of treating a disease state characterized by alterations to the mucin levels in a patient, the method comprising enterally administering to the patient a nutritional composition which has a protein source including amino acids wherein threonine comprises at least 5.5% by weight of the amino acids.
- 2. The method of claim 1 wherein threonine comprises at least 6% by weight of the amino acids.
- 3. The method of claim 1 wherein the protein source comprises sweet whey protein.
- 4. The method of claim 3 wherein the sweet whey protein is hydrolyzed.
- 5. The method of claim 1 wherein the nutritional composition further comprises a lipid source and a carbohydrate source.
- 6. The method of claim 5 wherein the lipid source comprises a mixture of medium chain triglycerides and long chain triglycerides.
- 7. The method of claim 6 wherein the lipid source comprises about 30% to about 80% by weight of medium chain triglycerides.
- 8. A method for maintaining the synthesis of mucins in a patient, the method comprising enterally administering to the patient a nutritional composition which has a protein source including amino acids wherein threonine comprises at least 5.5% by weight of the amino acids.
- 9. The method of claim 8 wherein the protein source comprises sweet whey protein.
- 10. The method of claim 9 wherein the sweet whey protein is hydrolyzed.
- 11. The method of claim 8 wherein the nutritional composition further comprises a lipid source and a carbohydrate source.
- 12. The method of claim 11 wherein the lipid source comprises a mixture of medium chain triglycerides and long chain triglycerides.
- 13. The method of claim 12 wherein the lipid source comprises about 30% to about 80% by weight of medium chain triglycerides.
- 14. A method for maintaining the synthesis of mucins in a patient, the method comprising enterally administering to the patient a nutritional composition which includes a protein source containing a therapeutically effective amount of threonine, a carbohydrate source and a lipid source including a mixture of medium chain triglycerides and long chain triglycerides.
- 15. The method of claim 14 wherein the amount of threonine comprises at least 5.5% by weight of amino acids of the protein source.
- 16. The method of claim 14 wherein the protein source comprises sweet whey protein.
- 17. The method of claim 14 wherein the sweet whey protein is hydrolyzed.
- 18. The method of claim 14 wherein the lipid source comprises about 30% to about 80% by weight of medium chain triglycerides.
- 19. The method of claim 14 wherein the protein source provides about 10% to about 20% of the energy of the nutritional composition.
- 20. A method of treating a disease state characterized by alterations to the mucin levels in a patient, the method comprising enterally administering to the patient a nutritional composition that has a protein source including amino acids wherein threonine comprises at least 7.4% by weight of the amino acids.
- 21. The method of claim 20 wherein threonine comprises at least 14% by weight of the amino acids.
- 22. The method of claim 20 wherein the protein source comprises a sweet whey protein.
- 23. The method of claim 20 wherein the protein source comprises a caseino-glyco-macropeptide.
- 24. A method for maintaining the synthesis of mucins in a patient, the method comprising enterally administering to the patient a nutritional composition which has a protein source including amino acids wherein threonine comprises at least 7.4% by weight of the acids.
- 25. The method of claim 24 wherein threonine comprises at least 14% by weight of the amino acids.
- 26. The method of claim 24 wherein the protein source comprises a sweet whey protein.
- 27. The method of claim 24 wherein the protein source comprises caseino-glyco-macropeptide.
- 28. A method for increasing the synthesis of mucins, the method comprising supplementing a diet of a patient by adding a therapeutically effective amount of threonine to the diet.
- 29. The method of claim 28 wherein the amount of threonine is at least 0.2mM.
- 30. The method of claim 28 wherein the amount of threonine is at least 0.8mM.
- 31. The method of claim 22 wherein the amount of threonine ranges from about 0.2mM to about 0.8mM.
- 32. A method for increasing the synthesis of mucins in a patient, the method comprising administering to the patient a nutritional composition which has a protein source containing theronine at least 30% of a daily recommended amount of threonine.
- 33. The method of claim 32 wherein the amount of threonine comprises at least 60% of the daily recommended amount of threonine.
- 34. The method of claim 32 wherein the amount of threonine comprises at least 100% of the daily recommended amount of threonine.
- 35. A method of treating intestinal inflammation in a patient, the method comprising administering to the patient a therapeutically effective amount of threonine.
- 36. The method of claim 35 wherein the threonine is provided as a nutritional supplement.
- 37. The method of claim 36 wherein the nutritional supplement contains threonine in an amount of at least 0.2mM.
- 38. The method of claim 36 wherein the nutritional supplement contains a protein source including amino acids and wherein the threonine is at least 5.5% by weight of amino acids.
- 39. The method of claim 36 wherein the nutritional supplement contains a sweet whey protein.
- 40. A method of treating intestinal bacterial infection in a patient, the method comprising administering a nutritional composition to the patient wherein the nutritional composition contains a therapeutically effective amount of threonine.
- 41. The method of claim 40 wherein the threonine is provided as a nutritional supplement.
- 42. The method of claim 41 wherein the nutritional supplement contains threonine in an amount of at least 0.2mM.
- 43. The method of claim 41 wherein the nutritional supplement contains a protein source including amino acids and wherein the threonine is at least 5.5% by weight of amino acids.
- 44. The method of claim 41 wherein the nutritional supplement contains a sweet whey protein.
- 45. A method of reducing oxidative stress due to acute intestinal inflammation, the method comprising administering a therapeutically effective amount of threonine.
- 46. The method of claim 45 wherein the threonine is part of a nutritional composition.
- 47. The method of claim 46 wherein the nutritional composition contains threonine in an amount of at least 0.2mM.
- 48. The method of claim 46 wherein the nutritional composition contains a protein source including amino acids and wherein the threonine is at least 5.5% by weight of amino acids.
- 49. The method of claim 48 wherein the nutritional composition contains a sweet whey protein.
Parent Case Info
[0001] The present application is a continuation-in-part application of U.S. patent application Ser. No. 09/498,905 filed on Feb. 4, 2000.
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
09498905 |
Feb 2000 |
US |
Child |
09774814 |
Jan 2001 |
US |