Claims
- 1. A method of preparing a monomer-dye compound, comprising the steps of:
- forming an aqueous solution comprising water and water-soluble reagents, said reagents comprising water-soluble hydrophilic monomer, water-soluble base, and water-soluble halotriazine dye;
- reacting said water-soluble dye with said water-soluble hydrophilic monomer to form a monomer-dye compound, wherein said monomer-dye compound is insoluble in said aqueous solution; and separating said monomer-dye compound from said solution comprising said water-soluble reagents.
- 2. The method of claim 1, wherein said separating step is accomplished by filtering.
- 3. The method of claim 2, further comprising during said filtering step, rinsing said monomer-dye compound with water.
- 4. The method of claim 3, further comprising during said filtering step, rinsing said monomer-dye compound with salt and water.
- 5. The method of claim 1, further comprising prior to said separating step the step of:
- adding salt to said aqueous solution.
- 6. The method of claim 1, wherein said water-soluble hydrophilic monomer is a hydroxy ester of acrylic or methacrylic acid.
- 7. The method of claim 1, wherein said hydrophilic monomer is 2-hydroxyethyl methacrylate.
- 8. The method of claim 1, wherein the amount of said hydrophilic monomer in said aqueous solution is about 10-65% by weight of the total weight of said reagents.
- 9. The method of claim 1, wherein equimolar amounts of said base and said dye are present in said solution during said forming step.
- 10. The method of claim 1, wherein the halotriazine dye is a dihalotriazine dye.
- 11. The method of claim 1, wherein said dye is a dichlorotriazine dye with at least one sulfonate functionality.
- 12. The method of claim 1, wherein filtering said dye-monomer compound from said aqueous solution and drying said monomer-dye compound will provide a monomer-dye compound having at least 50% purity as measure by High Pressure Liquid Chromatography.
- 13. A method of preparing a monomer-dye compound, comprising the steps of:
- forming an aqueous solution comprising water and water-soluble reagents, said reagents comprising water-soluble base, water-soluble hydrophilic monomer, and water-soluble vinyl-sulfone dye;
- reacting said water-soluble dye with said water-soluble hydrophilic monomer to form a monomer-dye compound, wherein said monomer-dye compound is insoluble in said aqueous solution; and separating said monomer-dye compound from said solution comprising said water-soluble reagents.
- 14. The method of claim 13, wherein said separating step is accomplished by filtering.
- 15. The method of claim 14, further comprising during said filtering step, rinsing said monomer-dye compound with water.
- 16. The method of claim 14, further comprising during said filtering step, rinsing said monomer-dye compound with salt and water.
- 17. The method of claim 13, further comprising prior to said separating step the step of:
- adding salt to said aqueous solution.
- 18. The method of claim 13, wherein said water-soluble hydrophilic monomer is a hydroxy ester of acrylic or methacrylic acid.
- 19. The method of claim 13, wherein said hydrophilic monomer is 2-hydroxyethyl methacrylate.
- 20. The method of claim 13, wherein the amount of said hydrophilic monomer in said aqueous solution is about 10-65% by weight of the total weight of said reagents.
- 21. The method of claim 13, wherein equimolar amounts of said base and said dye are present in said solution during said forming step.
- 22. The method of claim 14, wherein filtering said dye-monomer compound from said aqueous solution and drying said monomer-dye compound will provide a monomer-dye compound having at least 50% purity as measure by High Pressure Liquid Chromatography.
- 23. A monomer-dye compound formed by a method comprising the steps of:
- forming an aqueous solution comprising water and water-soluble reagents, said reagents comprising water-soluble hydrophilic monomer, water-soluble base, and water-soluble halotriazine dye;
- reacting said water-soluble dye with said water-soluble hydrophilic monomer to form a monomer-dye compound, wherein said monomer-dye compound is insoluble in said aqueous solution; and separating said monomer-dye compound from said solution comprising said water-soluble reagents.
- 24. A monomer-dye compound formed by a method comprising the steps of:
- forming an aqueous solution comprising water and water-soluble reagents, said reagents comprising water-soluble base, water-soluble hydrophilic monomer; and water-soluble vinyl-sulfone dye;
- reacting said water-soluble dye with said water-soluble hydrophilic monomer to form a monomer-dye compound, wherein said monomer-dye compound is insoluble in said aqueous solution; and separating said monomer-dye compound from said solution comprising said water-soluble reagents.
Parent Case Info
This application is a continuation-in-part of U.S. Ser. No. 08/603,383, filed Feb. 20, 1996, now abandoned, which is a continuation of U.S. Ser. No. 08/185,747, filed Jan. 24, 1994, now abandoned, which is a continuation-in-part of U.S. Ser. No. 07/966,232, filed Oct. 26, 1992, now abandoned, the entire contents of all three applications are incorporated by reference herein.
US Referenced Citations (22)
Foreign Referenced Citations (7)
Number |
Date |
Country |
A-0 072 353 |
Feb 1983 |
EPX |
A-0-396 376 |
Nov 1990 |
EPX |
A-0 595 575 |
May 1994 |
EPX |
62-265357 |
May 1986 |
JPX |
4-293010 |
Oct 1992 |
JPX |
A-1 400 892 |
Jul 1975 |
GBX |
A-92 11407 |
Jul 1992 |
WOX |
Non-Patent Literature Citations (2)
Entry |
"Analytical Evaluation of the Purity of Commercial Preparations of Cibacron Blue F3GA and Related Dyes" D. Hanggi and P. Carr; Anal. Biochem. vol. 149, pp. 91-104(Feb. 1985). |
English language translation of Seiko-Epson K.K., JP 4-293,010, pp. 1-16, Oct. 1992. |
Continuations (1)
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Number |
Date |
Country |
Parent |
185747 |
Jan 1994 |
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Continuation in Parts (2)
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Number |
Date |
Country |
Parent |
603383 |
Feb 1996 |
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Parent |
966232 |
Oct 1992 |
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