Claims
- 1. In a method for preparing optically active N-acetylindoline-2-carboxylic acid wherein N-acetylindoline-2-carboxylic acid and an optically active resolving agent provided in the form of an optically active .alpha.-amino-.epsilon.-caprolactam are dissolved in an inert solvent, and wherein a diastereomeric N-acetylindoline-2-carboxylic acid-resolving agent salt is precipitated from the solution formed therefrom by fractional crystallization and wherein said salts are separated and liberated to optically active free acids by treatment with stronger acids,
- the improvement wherein said inert solvent is water.
- 2. In a method for preparing optically active N-acetylindoline-2-carboxylic acid wherein N-acetylindoline-2-carboxylic acid, optically active resolving agent provided in the form of an optically active .alpha.-amino-.epsilon.-caprolactam and a base are dissolved in an inert solvent, and wherein a diastereomeric N-acetylindoline-2-carboxylic acid-resolving agent salt is precipitated from the solutiion formed therefrom by fractional crystallization and wherein said salts are separated and liberated to optically active free acids by treatment with stronger acids,
- the improvement wherein said inert solvent is water.
Priority Claims (1)
Number |
Date |
Country |
Kind |
59-144185 |
Jul 1984 |
JPX |
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Parent Case Info
This application is a continuation, of application Ser. No. 752,900, filed 7/8/85 now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4374847 |
Gruenfeld |
Feb 1983 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
0116468 |
Jul 1983 |
JPX |
0067271 |
Apr 1984 |
JPX |
Continuations (1)
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Number |
Date |
Country |
Parent |
752900 |
Jul 1985 |
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