Claims
- 1. A method of producing a 2-naphthamide derivative of formula (I), ##STR45## wherein R.sup.1 and R.sup.2 are each independently an unsubstituted or substituted aromatic hydrocarbon group, or an unsubstituted or substituted aromatic heterocyclic group; and R.sup.3 is an acyl group, an alkoxycarbonyl group, a substituted carbamoyl group, or an unsubstituted or substituted alkyl group, comprising the step of:
- allowing a compound of formula (VI), ##STR46## wherein R.sup.3 is the same as defined in formula (I), and R.sup.4 is an unsubstituted or substituted alkyl group having 1 to 6 carbon atoms, to react with an aminoethylpiperidine derivative of formula (III), ##STR47## wherein R.sup.1 and R.sup.2 are respectively the same as defined in formula (I).
- 2. The method as claimed in claim 1, wherein said compound of formula (VI) is prepared by allowing a dihydroxynaphthoic acid ester derivative of formula (IV), ##STR48## wherein R.sup.4 is the same as defined in formula (VI), to react with an alcohol derivative of formula (V),
- R.sup.3 --OH (V)
- wherein R.sup.3 is the same as defined in formula (I).
- 3. The method as claimed in claim 1, wherein R.sup.1 and R.sup.2 are each independently an unsubstituted or substituted aromatic hydrocarbon group.
- 4. The method as claimed in claim 3, wherein said unsubstituted or substituted aromatic hydrocarbon group represented by R.sup.1 or R.sup.2 an unsubstituted or substituted phenyl group.
- 5. The method as claimed in claim 1, wherein said substituted alkyl group represented by R.sup.3 is an alkyl group having 1 to 4 carbon atoms, with a substituent.
- 6. The method as claimed in claim 5, wherein said substituent of said alkyl group is an aromatic heterocyclic group.
- 7. The method as claimed in claim 6, wherein said aromatic heterocyclic group is a nitrogen-containing aromatic heterocyclic group.
- 8. The method as claimed in claim 7, wherein said nitrogen-containing aromatic heterocyclic group is a pyridyl group.
Priority Claims (3)
Number |
Date |
Country |
Kind |
7-160161 |
Jun 1995 |
JPX |
|
7-160162 |
Jun 1995 |
JPX |
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7-160163 |
Jun 1995 |
JPX |
|
Parent Case Info
This is a Division, of application Ser. No. 08/657,545 filed on Jun. 4, 1996, now U.S. Pat. No. 5,714,613.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4457935 |
Iwao et al. |
Jul 1984 |
|
5324728 |
Sekine et al. |
Jun 1994 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
0 492 178 |
Jul 1992 |
EPX |
Non-Patent Literature Citations (1)
Entry |
Hovorka et al. Tetrahedron vol. 48, No. 43, p. 9503-9516, 1992. |
Divisions (1)
|
Number |
Date |
Country |
Parent |
657545 |
Jun 1996 |
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