Patent Application
20240425531
This invention relates to a method for preparing cyclic silazane compounds.
Nitrogen-containing organoxysilane compounds are useful as silane coupling agents, surface treating agents, resin additives, paint additives and the like.
Known nitrogen-containing organoxysilane compounds include organoxysilane compounds having a primary amino group such as aminopropyltrimethoxysilane, organoxysilane compounds having a secondary amino group such as N-phenylaminopropyltrimethoxysilane, and organoxysilane compounds having a tertiary amino group such as dimethylaminopropyltrimethoxysilane. Of these, the organoxysilane compounds having a secondary amino group, referred to as “secondary aminosilane compounds,” hereinafter, can be subjected to intramolecular cyclization between the amino group and the alkoxysilane site in the molecule into cyclic silazane compounds.
The cyclic silazane compounds have the advantage that the amount of alcohol produced during hydrolysis can be reduced as compared with corresponding secondary aminosilane compounds. Since the cyclic silazane compounds do not possess active hydrogen on nitrogen, compositions obtained by mixing them with resins having a functional group capable of reacting with an amino group are stable unless they are brought into contact with alcohols or water. The cyclic silazane compounds are useful in this sense.
It is known that the Si—N structure in the cyclic silazane compounds is so reactive that it quickly reacts with airborne moisture and hydroxy groups in compounds, resulting in ring-opening. Thus, the cyclic silazane compounds can be used, for example, as surface treating agents in that they quickly react with reactive hydroxy groups on the metal surface.
When the cyclic silazane compounds are used as surface treating agents, any of various functions can be imparted to the article to be treated, depending on the type of substituent group on nitrogen. For example, it is possible to impart hydrophobic properties when cyclic silazane compounds have a hydrocarbon group such as butyl, octyl or phenyl, hydrophilic properties when cyclic silazane compounds have a hydrophilic functional group such as amino, and crosslinking ability when cyclic silazane compounds have an alkoxysilyl group.
Also, cyclic silazane compounds are fully hydrolyzable because they quickly react with airborne moisture. With the progress of hydrolytic condensation, a cured coating can be formed.
For the synthesis of cyclic silazane compounds, Patent Documents 1 and 2 propose a method comprising the steps of distilling a secondary aminosilane compound in the presence of a catalytic amount of an acidic or basic compound for inducing intramolecular cyclization to produce an alcohol, and removing the alcohol out of the system under reduced pressure.
For example, intramolecular cyclization reaction is carried out in the presence of sodium methoxide as the basic compound in Patent Document 1, and in the presence of sodium amide or sodium methoxide as the basic compound in Patent Document 2.
Also, Patent Document 3 proposes intramolecular cyclization of a secondary aminosilane compound in the presence of a catalytic amount of an acidic compound and a silylamine compound such as hexamethyldisilazane. This is an efficient synthesis method capable of restraining reverse reaction by letting the silylamine compound trap the alcohol resulting from intramolecular cyclization.
In the methods of Patent Documents 1 and 2, the equilibrium relationship between the secondary aminosilane compound and the cyclic silazane compound is varied by physically removing the alcohol. These methods, however, have the problem that the efficiency of alcohol removal is reduced as the reaction scale is increased. It takes a longer time until the cyclic silazane compound is formed. The conversion rate from the secondary aminosilane compound to the cyclic silazane compound is insufficient. In addition, to isolate the target compound, cyclic silazane compound, it is necessary to separate the cyclic silazane compound and the reactant, secondary aminosilane compound by distillation purification. There arise problems that the isolation yield is insufficient and the distillation purification takes a time. Because of long-term heating in the presence of an acidic or basic catalyst, the methods cannot be applied to those compounds which are unstable under acidic or basic conditions.
In particular, the method of Patent Document 2 uses a solid metal amide compound (e.g., sodium amide or potassium amide) which is highly reactive and must be carefully handled. Such reagents are less soluble in ordinary organic solvents with a possibility that a satisfactory conversion rate is not reached within a short time. The metal amide compound readily reacts with airborne moisture and is decomposed into a metal hydroxide and ammonia. The metal hydroxide causes to decompose the cyclic silazane compound whereas ammonia will react with the cyclic silazane compound and the secondary aminosilane compound to form higher molecular weight compounds. There is a possibility that yield and purity are reduced. Moreover, while the metal amide compound reacts with the alcohol which is produced along with formation of cyclic silazane during the reaction, it is decomposed into a metal alkoxide and ammonia. The formation of ammonia similarly invites a possibility that yield and purity are reduced.
In the method of Patent Document 3, the equilibrium relationship between the secondary aminosilane compound and the cyclic silazane compound is varied by causing a silylamine compound to react with the alcohol for chemical transformation. To increase the formation rate of the cyclic silazane compound, however, the reaction product of the silylamine compound and the alcohol must be removed from the reaction solution. This raises a problem like Patent Document 1.
Because of long-term heating under acidic conditions, the method cannot be applied to those compounds which are unstable under acidic conditions. Since the reaction product of silylamine compound and alcohol which is produced with the progress of reaction can react with the cyclic silazane compound, there is a problem that the desired cyclic silazane compound cannot be obtained or its purity is reduced.
An object of the invention, which has been made under the above-mentioned circumstances, is to provide a method for preparing cyclic silazane compounds at a high conversion rate within a short time.
Making extensive investigations to attain the above object, the inventors have found that a cyclic silazane compound is efficiently produced in a short time by subjecting a secondary aminosilane compound to intramolecular cyclization in the presence of an equivalent or more amount of a basic compound selected from organometallic compounds and organometallic amide compounds. The invention is predicated on this finding.
The invention provides the following.
1. A method for preparing a cyclic silazane compound comprising the step of subjecting an organoxysilane compound having a secondary amino group, represented by the general formula (1):
2. The method for preparing a cyclic silazane compound according to 1 wherein the metal is at least one element selected from lithium, sodium, potassium and magnesium.
3. A cyclic silazane compound having an alkoxysilyl group, represented by the general formula (3):
According to the preparation method of the invention, cyclic silazane compounds can be readily prepared at a high conversion rate in a short time. Even cyclic silazane compounds having the structure which is difficult to synthesize by the prior art methods can be synthesized.
The resulting cyclic silazane compounds find a variety of applications depending on the substituent group on nitrogen.
Now the invention is described in detail.
The invention provides a method for preparing a cyclic silazane compound having the general formula (2), referred to as “Compound (2),” hereinafter, comprising the step of subjecting an organoxysilane compound having a secondary amino group, represented by the general formula (1), referred to as “Compound (1),” hereinafter, to intramolecular cyclization in the presence of an equivalent or more amount of a basic compound selected from organometallic compounds and organometallic amide compounds.
Herein m is 0, 1 or 2.
In general, when Compound (1) is converted to Compound (2), an alcohol is produced. If the alcohol produced is left in the reaction system, the alcohol will react with Compound (2) to form Compound (1). That is, Compound (1) and Compound (2) are in equilibrium relationship as shown by the following scheme.
According to the invention, Compound (1) is subjected to intramolecular cyclization in the presence of a basic compound whereby the alcohol resulting from Compound (1) is converted to a metal alkoxide (R1O−) to inhibit the reverse reaction from Compound (2) to Compound (1). The equilibrium is thus biased toward the formation of Compound (2), ensuring that Compound (2) is obtained.
Herein m is 0, 1 or 2.
In formula (1), R1 and R2 are each independently a C1-C10, preferably C1-C6, more preferably C1-C3 unsubstituted monovalent hydrocarbon group.
The monovalent hydrocarbon groups R1 and R2 may be straight, branched or cyclic and examples thereof include straight alkyl groups such as methyl, ethyl, n-propyl, n-butyl, n-pentyl, n-hexyl, n-heptyl, n-octyl and decyl; branched alkyl groups such as isopropyl, isobutyl, sec-butyl, tert-butyl, neopentyl, thexyl and 2-ethylhexyl; cyclic alkyl groups such as cyclopentyl and cyclohexyl; alkenyl groups such as vinyl, allyl, propenyl, butenyl, pentenyl and octenyl; aryl groups such as phenyl and tolyl; and aralkyl groups such as benzyl and phenethyl.
Of these, methyl and ethyl are preferred from the aspect of availability of reactants.
R3 is a C1-C10, preferably C1-C6, more preferably C1-C3 monovalent hydrocarbon group which may contain an amino or alkoxysilyl group. Examples of the monovalent hydrocarbon group are as exemplified above for R1. Of these, propyl, butyl, octyl, octenyl and phenyl are preferred from the aspect of availability of reactants.
Examples of the amino-containing monovalent hydrocarbon group R3 include aminoalkyl groups such as aminoethyl, aminopropyl and aminooctyl: alkylaminoalkyl groups such as methylaminoethyl, ethylaminoethyl, butylaminoethyl, and tert-butylaminoethyl; dialkylaminoalkyl groups such as dimethylaminoethyl, diethylaminoethyl, morpholinoethyl, piperazinoethyl, and methylpiperazinoethyl: aminoalkylaminoalkyl groups such as aminoethylaminoethyl; and bis(trialkylsilyl)aminoalkyl groups such as bis(trimethylsilyl)aminoethyl.
Of these, aminoalkyl groups are preferred from the aspect of availability of reactants, with aminoethyl being more preferred.
Examples of the alkoxysilyl-containing monovalent hydrocarbon group R3 include trialkoxysilylalkyl groups such as trimethoxysilylpropyl, triethoxysilylpropyl, trimethoxysilylmethyl, triethoxysilylmethyl, trimethoxysilyloctyl, triethoxysilyloctyl, trimethoxysilylethylphenylmethyl, and triethoxysilylethylphenylmethyl; alkyldialkoxysilylalkyl groups such as methyldimethoxysilylpropyl and methyldiethoxysilylpropyl; and dialkylalkoxysilylalkyl groups such as dimethylmethoxysilylpropyl and dimethylethoxysilylpropyl.
Of these, trimethoxysilylpropyl and triethoxysilylpropyl are preferred from the aspect of availability of reactants, and trimethoxysilylpropyl, triethoxysilylpropyl, trimethoxysilylmethyl and triethoxysilylmethyl are preferred from the aspect of product usefulness.
Examples of Compound (1) include
The basic compound used in the inventive preparation method is selected from organometallic compounds and organometallic amide compounds.
Examples of the organometallic compounds include organolithium reagents such as n-butyllithium, tert-butyllithium, and phenyllithium; and organomagnesium reagents, typically Grignard reagents such as isopropylmagnesium chloride, sec-butylmagnesium chloride, tert-butylmagnesium chloride, and thexylmagnesium chloride.
Examples of the organometallic amide compounds include lithium amides such as lithium diisopropylamide, lithium isopropyl-tert-butylamide, lithium di(tert-butyl)amide, and lithium hexamethyldisilazide: sodium amides such as sodium diisopropylamide, sodium isopropyl-tert-butylamide, sodium di(tert-butyl)amide, and sodium hexamethyldisilazide: potassium amides such as potassium hexamethyldisilazide; and magnesium amides such as chloromagnesium diisopropylamide, chloromagnesium hexamethyldisilazide, and bromomagnesium hexamethyldisilazide.
Either one or a mixture of two or more of organometallic compounds and organometallic amide compounds may be used. The organometallic compounds and organometallic amide compounds may be used alone or in admixture as the basic compound.
Of the foregoing basic compounds, tert-butylmagnesium chloride, sodium hexamethyldisilazide and chloromagnesium hexamethyldisilazide are preferred from the aspects of reactivity and ease of handling.
A commercially available basic compound may be used as purchased or a basic compound prepared immediately before the reaction may be used. It is recommended to use a basic compound prepared immediately before the reaction, from the aspect of preventing the compound from deactivation. For the preparation of the basic compound, any well-known methods may be used. For example, the organometallic compound may be prepared by mixing a metal such as lithium or magnesium with an alkyl halide and inducing a metal-halogen exchange reaction. On the other hand, the organometallic amide compound may be prepared by mixing a metal, metal hydride or organometallic compound with an amine compound.
In the inventive preparation method, the basic compound may be used in the form of a solution. The solvent used herein is not particularly limited as long as it does not react with Compound (1) and Compound (2) and does not deactivate the basic compound. Examples include aromatic hydrocarbon solvents such as toluene and xylene, and ether solvents such as diethyl ether, tetrahydrofuran, cyclopentyl methyl ether, 4-methyltetrahydropyran, and methyl tert-butyl ether, which may be used alone or in admixture. In particular, tetrahydrofuran, cyclopentyl methyl ether, and 4-methyltetrahydropyran are preferred from the aspects of reactivity and yield.
Although the amount of the solvent used is not particularly limited, it is preferred from the aspects of economy and reactivity to use 100 to 3,000 g, more preferably 300 to 1,000 g of the solvent per 1.0 mole of Compound (1).
An (iso) paraffin compound such as hexane, octane, isooctane, decane, dodecane or isododecane may be used along with the solvent. Since the (iso) paraffin compound renders the reaction solution less polar, a salt formed with the progress of reaction is more likely to precipitate.
The amount of the basic compound used in the inventive preparation method is preferably 1.0 to 2.0 moles per 1.0 mole of Compound (1). From the aspect of reactivity, the amount is more preferably 1.0 to 1.5 moles, even more preferably 1.0 to 1.2 moles.
The reaction temperature, though not particularly limited, is preferably −10° C. to 150° C., more preferably 0 to 100° C.
The reaction time, though not particularly limited, is preferably 1 to 40 hours, more preferably 1 to 20 hours.
It is noted that the reaction is preferably carried out in an inert gas atmosphere such as nitrogen or argon in order to prevent Compound (1), Compound (2) and the basic compound from hydrolysis.
The reaction may be further promoted by causing the metal alkoxide (R1O−) produced in the course of reaction to further react with another compound.
Examples of the compound capable of reacting with the metal alkoxide include 2-chloropyridine, 2-bromopyridine, 2-chloropyrazine, 2-bromopyrazine, methyl 2-chlorobenzoate, ethyl 2-chlorobenzoate, 2-chloronitrobenzene, 4-chloronitrobenzene, 2-bromonitrobenzene, and 4-bromonitrobenzene.
When the compound capable of reacting with the metal alkoxide is used, the amount of the compound is preferably 1 to 1.5 moles, more preferably 1.05 to 1.2 moles relative to the metal alkoxide, though not particularly limited.
According to the inventive preparation method, an alkoxysilyl-containing cyclic silazane compound having the formula (3), referred to as “Compound (3),” hereinafter, is obtainable. Since Compound (3) has an aminomethylalkoxysilyl structure in its molecule, which is extremely more reactive than an aminopropylalkoxysilyl structure, it is extremely highly hydrolyzable and expected to find application to fast-curing materials and the like.
Herein R1, R2 and m are as defined above, and n is 0, 1 or 2.
In formula (3), R4 and R5 are each independently a C1-C6, preferably C1-C3 unsubstituted monovalent hydrocarbon group. Examples of the monovalent hydrocarbon group are as exemplified above for R1, but of 1 to 6 carbon atoms. Inter alia, alkyl groups of 1 to 3 carbon atoms are preferred, with methyl and ethyl being more preferred.
Examples of Compound (2), inclusive of Compound (3), obtained from the inventive preparation method include
Through the series of reactions, there is obtained a mixture containing Compound (2), the salt resulting from the basic compound, and the solvent, or sometimes such a mixture further containing Compound (1).
The desired Compound (2) may be isolated and purified from the mixture by any method selected from purifying methods for ordinary organic synthesis such as filtration, distillation, vacuum stripping, various chromatography processes, and treatment with adsorbents.
Inter alia, purification by distillation is preferred because the desired compound is obtained in high purity. More preferably, the salt resulting from the metal compound is filtered off before distillation.
Examples and Comparative Examples are given below for further illustrating the invention although the invention is not limited thereto.
In Examples and Comparative Examples, the conversion rate is determined by performing gas chromatography (GC) analysis and calculating according to the following formula from the area values of reactant and product.
(area value of Compound 3)/(area value of Compound 1+area value of Compound 3)×100
Herein Me stands for methyl (the same holds true, hereinafter).
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with a 40 wt % tetrahydrofuran (THF) solution of 24.1 g (0.0526 mol) of sodium hexamethyldisilazide, and cooled at 5° C. To the flask, 17.1 g (0.0500 mol) of bis(trimethoxysilylpropyl)amine was added dropwise over 20 minutes, followed by 5 minutes of stirring at the temperature. A gas chromatography (GC) analysis of the reaction solution revealed that 2,2-dimethoxy-N-trimethoxysilylpropyl-1-aza-2-silacyclopentane was formed at a conversion rate of 99%.
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with a 30 wt % methyltetrahydropyran (MTHP) solution of 85.7 g (0.116 mol) of chloromagnesium hexamethyldisilazide, and heated at 60° C. To the flask, 34.1 g (0.100 mol) of bis(trimethoxysilylpropyl)amine was added dropwise over 1 hour, followed by 1 hour of aging at the temperature. The reaction solution was then aged at 100° C. for 1 hour. A GC analysis of the reaction solution revealed that 2,2-dimethoxy-N-trimethoxysilylpropyl-1-aza-2-silacyclopentane was formed at a conversion rate of 93%.
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with a 18 wt % THF solution of 76.2 g (0.117 mol) of tert-butylmagnesium chloride, and heated at 60° C. To the flask, 34.1 g (0.100 mol) of bis(trimethoxysilylpropyl)amine was added dropwise over 1 hour, followed by 1 hour of aging at the temperature. The reaction solution was then aged under reflux for 1 hour. A GC analysis of the reaction solution revealed that 2,2-dimethoxy-N-trimethoxysilylpropyl-1-aza-2-silacyclopentane was formed at a conversion rate of 85%.
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen and charged with a 40 wt % THF solution of 58.1 g (0.0127 mol) of sodium hexamethyldisilazide. To the flask, 31.0 g (0.124 mol) of N-butyl(trimethoxysilylpropyl)amine was added dropwise over 1 hour. The reaction solution was then stirred at 60° C. for 2 hours. A GC analysis of the reaction solution revealed that 2,2-dimethoxy-N-butyl-1-aza-2-silacyclopentane was formed at a conversion rate of 92%.
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen and charged with a 40 wt % THF solution of 58.1 g (0.0127 mol) of sodium hexamethyldisilazide. To the flask, 22.4 g (0.100 mol) of aminoethylaminopropyltrimethoxysilane was added dropwise over 1 hour. The reaction solution was then stirred at 60° C. for 2 hours. A GC analysis of the reaction solution revealed that 2,2-dimethoxy-N-(aminoethyl)-1-aza-2-silacyclopentane was formed at a conversion rate of 60%.
Herein Et stands for ethyl (the same holds true, hereinafter).
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with a 40 wt % THE solution of 73.0 g (0.159 mol) of sodium hexamethyldisilazide, and cooled at 5° C. To the flask, 72.1 g (0.145 mol) of (triethoxysilyloctyl) (triethoxysilylpropyl)amine was added dropwise over 1 hour. The reaction solution was stirred at the temperature for 1 hour. A GC analysis of the reaction solution revealed that 2,2-diethoxy-N-triethoxysilyloctyl-1-aza-2-silacyclopentane was formed at a conversion rate of 88%.
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with a 40 wt % THF solution of 126.1 g (0.2752 mol) of sodium hexamethyldisilazide, and cooled at 5° C. To the flask, 99.3 g (0.250 mol) of (triethoxysilylmethyl) (triethoxysilylpropyl)amine was added dropwise over 1 hour. The reaction solution was stirred at the temperature for 1 hour.
A GC analysis of the reaction solution revealed that 2,2-diethoxy-N-triethoxysilylmethyl-1-aza-2-silacyclopentane was formed at a conversion rate of 97%. Also, the reaction solution was filtered and then distilled, obtaining 54.0 g of 2,2-diethoxy-N-triethoxysilylmethyl-1-aza-2-silacyclopentane as a fraction having a boiling point of 105° C./0.4 kPa. The compound was analyzed by IR and 1H-NMR spectroscopy, with the results shown in
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with a 30 wt % MTHP solution of 85.7 g (0.116 mol) of chloromagnesium hexamethyldisilazide, and heated at 60° C. To the flask, 39.7 g (0.100 mol) of (triethoxysilylpropyl) (triethoxysilylmethyl)amine was added dropwise over 1 hour. The reaction solution was aged at 100° C. for 1 hour. A GC analysis of the reaction solution revealed that 2,2-diethoxy-N-triethoxysilylmethyl-1-aza-2-silacyclopentane was formed at a conversion rate of 98%.
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with a 30 wt % MTHP solution of 85.7 g (0.116 mol) of chloromagnesium hexamethyldisilazide, and heated at 60° C. To the flask, 31.3 g (0.100 mol) of (trimethoxysilylpropyl) (trimethoxysilylmethyl)amine was added dropwise over 1 hour. The reaction solution was aged at 100° C. for 1 hour. A GC analysis of the reaction solution revealed that 2,2-dimethoxy-N-trimethoxysilylmethyl-1-aza-2-silacyclopentane was formed at a conversion rate of 100%. Also, the reaction solution was filtered and then distilled, obtaining 47.0 g of 2,2-dimethoxy-N-trimethoxysilylmethyl-1-aza-2-silacyclopentane as a fraction having a boiling point of 109° C./0.8 kPa. The compound was analyzed by IR and 1H-NMR spectroscopy, with the results shown in
A three-necked glass flask equipped with a thermometer, reflux condenser, and distillation column was purged with nitrogen and charged with 170.5 g (0.500 mol) of bis(trimethoxysilylpropyl)amine and 0.27 g (0.0050 mol) of sodium methoxide. The reaction solution was heated under 0.6 kPa and kept under reflux for 5 hours while collecting methanol in a low-temperature trap. On GC analysis of the reaction solution, the conversion rate was 51%.
A four-necked glass flask equipped with a stirrer, thermometer, and reflux condenser was purged with nitrogen, charged with 170.5 g (0.500 mol) of bis(trimethoxysilylpropyl)amine and 0.82 g (0.0025 mol) of dodecylbenzenesulfonic acid, and heated at 130° C. To the flask, 89.7 g (0.500 mol) of N-trimethylsilyl-N-methylaniline was added dropwise over 1 hour, followed by 2 hours of aging at the temperature. On GC analysis of the reaction solution at this point of time, the conversion rate was 75%.
The reaction solution was transferred to a three-necked glass flask equipped with a thermometer, reflux condenser, and distillation column. The solution was aged for 2 hours while withdrawing a low-boiling fraction, trimethylmethoxysilane. On GC analysis of the reaction solution, the conversion rate was 85%.
A three-necked glass flask equipped with a thermometer, reflux condenser, and distillation column was purged with nitrogen and charged with 99.3 g (0.250 mol) 99.4 g (0.250 mol) of (triethoxysilylmethyl) (triethoxysilylpropyl)amine and 0.17 g (0.0025 mol) of sodium ethoxide. The reaction solution was heated under 0.5 kPa and kept under reflux for 5 hours while collecting ethanol in a low-temperature trap. On GC analysis of the reaction solution, the conversion rate was 33%. Part of the reactant was decomposed into low-boiling compounds.
A four-necked glass flask equipped with a stirrer, thermometer, reflux condenser, and distillation column was purged with nitrogen, charged with 39.7 g (0.100 mol) of (triethoxysilylmethyl) (triethoxysilylpropyl)amine, 0.33 g (0.0010 mol) of dodecylbenzenesulfonic acid, and 44 g of toluene, and heated under reflux at 130° C. To the flask, 17.9 g (0.100 mol) of N-trimethylsilyl-N-methylaniline was added dropwise over 1 hour. As trimethylethoxysilane was formed, it was withdrawn along with toluene. On GC analysis of the reaction solution, the conversion rate was 8%. There were found disiloxane compounds resulting from reaction of trimethylethoxysilane (produced with the progress of reaction) with the reactant, (triethoxysilylmethyl) (triethoxysilylpropyl)amine or the product, 2,2-diethoxy-N-triethoxysilylmethyl-1-aza-2-silacyclopentane.
A comparison of Examples 1 to 3 with Comparative Examples 1 and 2 reveals that a high conversion rate is reached within a short time according to the preparation method of the invention. Specifically, in Comparative Example 1 wherein the cyclization rate is so low, the desired cyclic silazane compound and the reactant must be separated by distillation purification. In Comparative Example 2, the additional step of removing the low-boiling fraction resulting from reaction must be taken before a high conversion rate can be reached.
A comparison of Examples 7 and 8 with Comparative Examples 3 and 4 reveals that the preparation method of the invention is successful in obtaining the desired compound at a satisfactory conversion rate whereas the prior art methods reach a very low conversion rate or accompany side reactions.
The cyclic silazane compounds obtained in Examples 8 and 9 have an aminomethylalkoxysilyl structure in the molecule, which is known to have an extremely higher reactivity than an aminopropylalkoxysilyl structure. Owing to extremely high hydrolysis, the cyclic silazane compounds are expected to find application to fast-curing materials.
| Number | Date | Country | Kind |
|---|---|---|---|
| 2021-158830 | Sep 2021 | JP | national |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/JP2022/033658 | 9/8/2022 | WO |
