Claims
- 1. A method for producing L-tryptophan, which comprises:
- culturing Coryneform glutamic acid-producing bacteria in a culture medium capable of producing L-tryptophan and then recovering the L-tryptophan accumulated in said culture medium,
- wherein said Coryneform glutamic acid-producing bacteria contain a plasmid capable of self-replicating cells of Coryneform glutamic acid-producing bacteria, said plasmid containing therein an antranilic acid phosphoribosyl transferase gene obtained from a Brevibacterium glutamic acid-producing bacteria.
- 2. The method according to claim 1, wherein said microorganism containing said plasmid is FERM-BP-275 or FERM-EP-276.
- 3. The method according to claim 1, wherein said microorganism is a Coryneform glutamic acid-producing bacteria resistant to a tryptophan antagonist.
- 4. The method according to claim 3, wherein said tryptophan antagonist is selected from the group consisting of 4-fluorotryptophan, 5-fluorotryptophan, 6-fluorotryptophan, 7-fluorotryptophan, 4-methyltryptophan, 5-methyltryptophan, 6-methyltryptophan, 7-methyltryptophan, napthylalanine, indoleacrylic acid, naphthylacrylic acid, .beta.-(2-benzothienyl)-alanine, styrylacetic acid, indole ad tryptopzan.
- 5. A Coryneform glutamic acid-producing bacterium selected from the group consisting of FERM-BP-275 and FERM-BO-276.
Priority Claims (1)
Number |
Date |
Country |
Kind |
58-71945 |
Apr 1983 |
JPX |
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Parent Case Info
This application is a continuation of application Ser. No. 06/948,396, filed on Dec. 30, 1986, now abandoned, which is a continuation of Ser. No. 06/602,330, filed Apr. 20, 1984, now abandoned.
Foreign Referenced Citations (3)
Number |
Date |
Country |
0058889 |
Sep 1982 |
EPX |
0124048 |
Nov 1984 |
EPX |
2098603 |
Nov 1982 |
GBX |
Non-Patent Literature Citations (1)
Entry |
Aiba, et al., Applied & Environmental Microbiology, vol. 43(2), pp. 289-297, 1982. |
Continuations (2)
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Number |
Date |
Country |
Parent |
948396 |
Dec 1986 |
|
Parent |
602330 |
Apr 1984 |
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