"A Survey of Compounds From the Antiradiation Drug Development Program of the U.S. Army Medical Research and Development Command," Walter Reed Army Institute of Research, Washington, DC, Sep. 1979. |
Corn, B. W., Liber, H. L., and Little, J. B., "Differential Effects of Radical Scavengers on X-Ray-Induced Mutation and Cytotoxicity in Human Cells," Radiation Research 109, 100-108 (1987). |
Nygaard, O. F. and Simic, M. G., excerpt from Radioprotectors and Anticarcinogens, 73-85, (1983). |
Grdina, D. J., Dale, P. and Weichselbaum, R., "Protection Against AZT-Induced Mutagenesis at the HGPRT Locus in a Human Cell Line by WR-151326," submitted for publication in Jan. 1991 to The International Journal of Radiation Oncology, Biology, Physics; presented at the Seventh International Conference on Chemical Modifiers for Cancer Treatment, Clearwater, Florida, Feb. 2-5, 1991. (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38; NIH/NCI grant CA-37435, U.S. Bioscience Inc. and the Center for Radiation Therapy.). |
Milas, L., Hunter, N. and Stephens, L. C. and Peters, L. J., "Inhibition of Radiation Carcinogenesis in Mice by S-2(3-Aminopropylamino)-Methylphosphorothioic Acid," Cancer Research, vol. 44, 5567-5569, Dec. 1984. (Supported in part by grants CA-06294 and CA-16672, provided by the National Cancer Institute, Department of Health and Human Services.). |
Grdina, D. J., Carnes, B. A., Grahn, D. and Sigdestad, C. P., "Protection Against Late Effects of Radiation by S-2-(3-Aminopropylamino)-Ethylphosphorothioic Acid," submitted to Cancer Research, vol. 51, 4125-4130 (1991). (Supported by the U.S. Department of Energy, under contract W-31-109-ENG-38; by NIH/NCI grant CA-37435 and by the Center for Radiation Therapy.). |
Brown, J. M., "Sensitizers and Protectors and Radiotherapy," Cancer, 2222-22228, May 1 Supplement, 1985. |
Constine, L. S., Zagars, G., Rubin, P. and Kligerman, M., "Protection by WR-2721 of Human Bone Marrow Function Following Irradiation," Int. J. Radiation Oncology Biol. Phys. vol. 12, 1505-1508, (1986). |
Mahoney, F., "Summary Statement", Radiation Study Section, Feb. 1986. |
Grdina, D. J., Nagy, B., Hill, C. K. and Sigdestad, C. P., "Protection Against Radiation-Induced Mutagenesis in V79 Cells by 2-[(Aminopropyl)amino] Ethanethiol Under Conditions of Acute Hypoxia," Radiation Research vol. 117, 251-258 (1989). |
"Summary Statement," Radiation Study Section, Jan. 1989. Maisin, J. R., Mattelin, G. and Lambiet-Collier, M., Chemical Protection Against the Long-Term Effects of a Single Whole-Body Exposure of Mice to Ionizing Radiation, Radiation Research 71, 119-131 (1977). |
Kataoka, Y., Basic, I., Perrin, J. and Grdina, D. J., "Anti-mutagenic effects of radioprotector WR-2721 against fission-spectrum-neutrons and Co-gamma rays in mice," Int. J. Radiation Oncology Biol Phys., vol. 61, 387-392 (1992). (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38; NIH/NCI CA-37435 and the Center for Radiation Therapy in Chicago, Illinois). |
Fry, R. J. M., "Radiation Carcinogenesis: Radioprotectors and Photosensitizers," Radioprotectors and Anticarcinogens, 417-436, (1983). (Supported by the Office of Health and Environmental Research, U.S. Department of Energy, under contract W-7405-eng-26 with the Union Carbide Corporation.). |
Held, K. D., "Models for Thiol Protection of DNA in Cells," Pharmac. Ther., vol. 39, 123-131, (1988). (Supported in part by PHS grants CA42167 awarded by the National Cancer Institute, DHHS). |
Grdina, D. J. and Sigdestad, C. P., "Radiation Protectors: The Unexpected Benefits," Drug Metabolism Reviews, 20(1), 13-42, (1989). (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-103-ENG-38 and Public Health Service grant CA37435 awarded (D. J. G.) by the National Cancer Institute, Department of Human Services; and the U.S. Army Medical Research and Development Command, Fort Detrick, Maryland, under contracts DAMD17-86-C-6229 and DAMD17-C-7218 (C. P. S). |
"1990 AACR Abstract Form" Temporary Abst. No. 247, of the paper Antimutagenic and Anticarcinogenic Effects of Aminothiols: Applications to the Clinic and Workplace. (Supported in part by U.S. Department of Energy contract W-31-109-ENG-38; NIH-NCI CA-37435 and the Center for Radiation Therapy in Chicago, Illinois). |
"Abstracts," 3rd International Conference on Anticarcinogenesis & Radiation Protection, Oct. 15-21, 1989. |
"Abstracts," twenty-eighth Plenary Meeting of the Committee on Space Research, Jun. 26-Jul. 6, 1990. |
Kataoka, Y., Basic, I., Perrin, J. and Gridina, D. J., "Antimutagenic effects of radioprotector WR-2721 against fission-spectrum neutrons .sup.60 Co gamma-rays in mice," Int. J. Radiat. Biol., (1992). (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38; NIH/NCI CA-37435 and the Center for Radiation Therapy in Chicago, Illinois). |
Zhang, X., Lai, P. and Taylor, Y., "Differential Radioprotection of Cultured Human Diploud Fibroblasts and Fibrosarcoma Cells by WR1065," International Journal of Radiation Oncology, Biology, Physics, vol. 21, Supp. 1 (1991). |
Corn, B. W., Liber, H. L. and Little, J. B., "Differential Effects of Radical Scavengers on X-Ray-Induced Mutations and Cytotoxicity in Human Cells," Radiation Research 109, 100-108, (1987). |
Grdina, D. J., Kataoka, Y., Basic, I. and Perrin, J., "The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes and administered prior to or following irradiation," Carcinogenesis, 13, 811-814 (1992). (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38; NIH/NCI CA-37435 and the Center for Radiation Therapy in Chicago, Illinois). |
Grdina, D. J., Carnes, B. A., Grahn, D. and Sigdestad, C. P., "Protection against Late Effects of Radiation by S-2-(3-Aminopropylamino)-ethylphosphorothioic Acid," Cancer Research vol. 51, 4125-4130, Aug. 15, 1991. Supported by the U.S. Department of Energy under contract W-31-109-ENG-38, by NIH/NCI grant CA-37435 and by the Center for Radiation Therapy.). |
Carnes, B. A and Grdina, D. J., "In vivo protection by the aminothiol WR-2721 against neutron-induced carcinogenesis," Int. J. Radiat. Biol. 61, 567-576 (1992). (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38; NIH/NCI CA-37435 and the Center for Radiation Therapy in Chicago, Illinois). |
Grdina, D. J., Wright, B. J. and Carnes, B. A., "Protection by WR-151327 against Late-Effect Damage from Fission-Spectrum Neutrons," Radiation Research 127, (1991). (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38, the Center of Radiation Therapy and NIH-NCI grant CA-37435.). |
Kataoka, Y., Basic, I., Perrin, J. and Grdina, D. J., "Anti-mutagenic effects of radioprotector WR-2721 against fission-spectrum-neutrons and .sup.60 Co gamma-rays in mice," Int. J. Radiat. Biol., (1991). (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38; NIH/NCI CA-37435 and the Center for Radiation Therapy in Chicago, Illinois). |
Smoluk, G. D., Fahey, R. C., Calabro-Jones, P. M., Aguilera, J. A. and Ward, J. F., "Radioprotection of Cells in Culture by WR-2721 and Derivatives: Form the Drug Responsible for Protection," Cancer Research vol. 48, 3641-3647, Jul. 1, 1988. (Supported by grant CA-39582 from the National Cancer Institute). |
Holwitt, E. A., Koda, E. and Swenberg, C. E., "Enhancement of Toposomerase I-Mediated Unwinding of Supercoiled DNA by the Radioprotector WR-33278," Radiation Research 124, 107-109, (1990). |
Grdina, D. J., Dale, P. and Weichselbaum, R., "Protection Against AZT-Induced Mutagenesis at the HGPRT Locus in a Human Cell Line by WR-151326," submitted to The International Journal of Radiation Oncology, Biology, Physics for publication; presented at the Seventh International Conference on Chemical Modifiers of Cancer Treatment, Clearwater, Florida, Feb. 2-5, 1991. (Supported in part by the U.S. Department of Energy, Office of Health and Environmental Research, under contract W-31-109-ENG-38, NIH-NCI grant CA-37435, U.S. Bioscience Inc. and the Center for Radiation Therapy.). |
Milas, L., Hunter, N., Stephens, L. C. and Peters, L. J., "Inhibition of Radiation Carcinogenesis in Mice by S-2-(3-Aminopropylamino)ethylphosphorothioic Acid," Cancer Research, vol. 44, 5567-5569, Dec. 1984. (Supported in part by grants CA-06294 and CA-16672 awarded by the National Cancer Institute, Department of Health and Human Services.). |
Benova, D., "Antimutagenic Properties of WR 2721 and of a Radioprotective Mixture, ATP-AET-Serotonin, With Regard to X Ray Induced Reciprocal Translocations in Mouse Spermatogonia," Int. J. Radiation Oncology Biol. Phys., vol. 13, 117-119 (1987). |
Linnane, A. W., Zhang, C., Baumer, A. and Nagley, P., "Mitochondrial DNA Mutation and the Ageing Process: Bioenergy and Pharmacological Intervention," Mutation Research, vol. 275, 195-208 (1992). |
"Preface: Aging of the 25th Chromosome," Mutation Research, vol. 275, 113-114 (1992). |
Minnunni, M., Wolleb, U., Mueller, O., Pfeifer, A., Aeschbacher, H. U., "Natural Antioxidants as Inhibitors of Oxygen Species Induced Mutagenicity," Mutation Research, vol. 269, 193-200 (1992). |
Holmes, G. E., Bernstein, C. and Bernstein H., "Oxidative and Other DNA Damages as the Basis of Aging: A Review," Mutation Research, vol. 275, 305-315 (1992). |
Rosin, M. P. and Stich, H. F., "The Inhibitory Effect of Cysteine on the Mutagenic Activities of Several Carcinogens," Mutation Research, vol. 54, 73-81 (1978). |
Wei, Y. H., "Mitochondrial DNA Alterations as Ageing-Associated Molecular Events," Mutation Research, vol. 275, 145-153 (1992). |
Applegate, L. A., Lautler, D. and Tyrrell, R. M., "Endogenous Glutathoine Levels Modulate the Frequency of Both Spontaneous and Long Wavelength Ultraviolet Induced Mutations in Human Cells," Carcinogenesis, vol. 13, No. 9, 1557-1560 (1992). |
Kirkwood, T. B. L. "DNA, mutations, and aging," Mutation Research, vol. 219, 1-7 (1989). |
Nagy, B., Dale, P. and Grdina, D., "Protection Against cis-Diammine-dichloroplatinum Cytotoxicity and Mutagenicity In V79 Cells by 2-[(Aminopropyl)amino]ethanethiol," Cancer Research, vol. 46, 1132-1135 (Mar. 1986). |
Nagy, B. and Grdina, D., "Protective Effects of 2-[(Aminopropyl)amino]Ethanethiol Against Bleomycin and Nitrogen Mustard-Induced Mutagenicity in V79 Cells," The International Journal of Radiation Oncology, Biology, Physics, vol. 12, 1475-1478 (Aug. 1986). |
Grdina, D. J. and Meechan, P. J., "Effects of the Radioprotector WR-1065 on Normal Human Skin Fibroblast Cells in Culture", Radiation Research Meeting, Mar. 19-25, 1993. |
Grdina, D. J., Constantinou, A. and Shigematsu, N., "Inhibition of Topoisomerase II Activity in Repair-Proficient CHO K1 Cells by WR-1065", Radiation Research Meeting, Mar. 19-25, 1993. |
Kataoka, Y., Shigematsu, N., O'Conner, T., Ward, W. and Grdina, D. J., "Captopril Protects Against Mutagenesis at the HPRT Locus in .sup.60 Co y-Ray-Irradiated CHO-AA8 Cells", Radiation Research Meeting, Mar. 19-25, 1993. |
Van Beek, M. Doak, R., Sigdestad, C., and Grdina, D. J., "Pathological Effects of the Radiation Protector WR-151327 in Mice", Radiation Research, 124, 79-84 (1990). |
Grdina, D. J., Nagy, B., Hill, C., Wells, R. and Peraino, C., "The radioprotector WR-1065 reduces radiation-induced mutations at the hypoxanthing-guanine phophoribosyl transferase locus in V79 cells", Carcinogenesis, vol. 6, No. 6, pp. 929-931, 1985. |