Claims
- 1. A method for reducing excess extracellular fluid in a subject undergoing hemodialysis comprising administering a V-1 receptor agonist to the subject in an effective amount and thereby maintaining blood pressure during hemodialysis in order to facilitate reducing excess extracellular fluid in the subject.
- 2. A method for stabilizing high blood pressure between hemodialysis treatments in a subject undergoing hemodialysis by reducing excess extracellular fluid by the method of claim 1.
- 3. A method for inhibiting interdialytic hypertension by regulating blood pressure by the method of claim 2.
- 4. A method for inhibiting intradialytic hypotension by regulating blood pressure by the method of claim 1.
- 5. The method of claim 1, wherein the V-1 receptor agonist is arginine vasopressin.
- 6. The method of claim 1, wherein the V-1 receptor agonist is lysine vasopressin.
- 7. The method of claim 1, wherein the V-1 receptor agonist is terlipressin.
- 8. The method of claim 1, wherein the V-1 receptor agonist is octapressin
- 9. The method of claim 1, wherein the V-1 receptor agonist is ornipressin
- 10. The method of claim 1, wherein the V-1 receptor agonist is an organic molecule selected from the group consisting of 3-beta-(2-thienyl)-L-alanine)-8-lysine-vasopressin, N-alpha-glycyl-glycyl-glycyl-[8-lysine]-vasopressin, and 1-deamino-6-carba-[8-arginine]-vasopressin.
- 11. The method of claim 1, wherein the effective amount of the V-1 receptor agonist is in a range of about 0.05 milliunits/kg/minute−2.0 milliunits/kg/hr.
- 12. The method of claim 1, wherein the effective amount of the V-1 receptor agonist is about 0.3 milliunits/kg/minute.
- 13. The method of claim 1, wherein the subject is a human, non-human primate, rabbit, sheep, rat, dog, cat, pig, or mouse.
Parent Case Info
[0001] This patent application claims the benefit of the filing date of U.S. Ser. No. 60/450,609, filed Feb. 26, 2003, the contents of all of the foregoing application are incorporated by reference in their entireties into the present patent application.
[0002] Throughout this application various publications are referenced. The disclosures of these publications in their entireties are hereby incorporated by reference into this application in order to more fully describe the state of the art to which this invention pertains.
Provisional Applications (1)
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Number |
Date |
Country |
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60450609 |
Feb 2003 |
US |