Claims
- 1. A method for the healing of wounds caused by corneal injury in a mammalian patient, which comprises administering to the mammalian patient in need thereof an effective wound healing amount of lactoferrin and lactoperoxidase as active ingredients, either alone or in admixture with at least one excipient.
- 2. The method according to claim 1, wherein said excipients are sodium chloride and sterile purified water.
- 3. The method according to claim 1, wherein said lactoferrin and lactoperoxidase are instilled into an eye of said patient.
- 4. The method according to claim 3, wherein eye drops are instilled which contain said lactoferrin and lactoperoxidase, in a concentration from 0.01 to 3.0 (W/W) %.
- 5. A method for the healing of wounds caused by corneal injury in a mammalian patient which comprises administering to the mammalian patient in need thereof an effective corneal wound healing amount of an active ingredient, said active ingredient for corneal wound healing consisting essentially of lactoferrin, either alone or in admixture with at least one excipient.
- 6. The method according to claim 5, wherein said excipients are sodium chloride and sterile purified water.
- 7. The method according to claim 5, wherein said lactoferrin is instilled into an eye of said patient.
- 8. The method according to claim 7, wherein eye drops are instilled which contain said lactoferrin in a concentration from 0.01 to 3.0 (W/W) %.
- 9. A method of for the healing of wounds caused by corneal disorders injury in a mammalian patient, which comprises administering to the mammalian patient in need thereof an effective wound healing amount of lactoperoxidase as an active ingredient, either alone or in admixture with at least one excipient.
- 10. The method according to claim 9, wherein said excipients are sodium chloride and sterile purified water.
- 11. The method according to claim 9, wherein said lactoperoxidase is instilled into an eye of said patient.
- 12. The method according to claim 11, wherein eye drops are instilled which contain said lactoperoxidase in a concentration from 0.01 to 3.0 (W/W) %.
- 13. A method of healing corneal injury caused by ulceration, inflammation or ophthalmological surgery comprising instilling into an eye of a mammalian patient in need thereof an effective healing amount of an active ingredient selected from the group consisting of lactoferrin, lactoperoxidase and a combination of lactoferrin and lactoperoxidase, either alone or in admixture with a pharmaceutically acceptable diluent.
- 14. The method according to claim 13, wherein said active ingredient is instilled in the form of eye drops, said eye drops containing said active ingredient in a concentration of 0.01 to 3.0 (W/W) %.
Priority Claims (1)
Number |
Date |
Country |
Kind |
2-308036 |
Nov 1990 |
JPX |
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Parent Case Info
This application is a Continuation of application Ser. No. 08/064,037, filed May 7, 1993, now abandoned, which is the United States national phase application of International Application No. PCT/JP91/01539 filed Nov. 8, 1991.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4726948 |
Pripels et al. |
Feb 1988 |
|
4745100 |
Gilbard et al. |
May 1988 |
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Foreign Referenced Citations (3)
Number |
Date |
Country |
2-48534 |
Feb 1990 |
JPX |
2052979 |
Feb 1981 |
GBX |
WO8707838 |
Dec 1987 |
WOX |
Non-Patent Literature Citations (3)
Entry |
Dorland's Illustrated Medical Dictionary, Twenty-fifth Edition, Publisher-W. B. Saunders Company, 1974, p. 319. |
Bannister et al, Enhanced Production Of Hydroxy Radicals By The Xanthine-Xanthine Oxidase Reaction In The Prsence Of Lactoferrin, Biochemica et Biophysica Acta, vol. 715, No. 1, (1982), pp. 116-120. |
Exp. Eye Res. vol. 34, (1982) abstract. |
Continuations (1)
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Number |
Date |
Country |
Parent |
64037 |
May 1993 |
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