Claims
- 1. A method of treating or ameliorating an indication of the invention in an animal, including a human, comprising administering an effective amount of a compound of the formula I:
- 2. The method of claim 1, wherein the compound administered is 1,5-dicyclohexyl-3-(2-phenyl-2-oxoethyl)imidazolium salt.
- 3. The method of claim 11, wherein the compound administered is 1,5-dicyclohexyl-3-(2-cyanomethyl)imidazolium salt.
- 4. A compound of the formula Ia
- 5. The compound of claim 4, wherein at least one of R1 and R2 is other than hydrogen.
- 6. The compound of claim 4, wherein M is cyclohexyl.
- 7. The compound of claim 4, wherein Ar is phenyl.
- 8. The compound of claim 4: 1,5-dicyclohexyl-3-(2-phenyl-2-oxoethyl)imidazolium salt.
- 9. The compound of claim 4: 1,5-dicyclohexyl-3-(2-cyanomethyl)imidazolium salt.
- 10. A pharmaceutical composition comprising the compound of claim 4 and a pharmaceutically acceptable carrier.
- 11. A compound of the formula II
- 12. The compound of claim 11, wherein Ar is phenyl.
- 13. The compound of claim 11, wherein M is alkyl.
- 14. The compound of claim 11, wherein R1 and R2 are hydrogen.
- 15. The compound of claim 11: 3-(2-phenyl-2-oxoethyl)-1-methyl-2-aminoimidazolium salt.
- 16. A pharmaceutical composition, comprising a compound of claim 11 and a pharmaceutically acceptable carrier.
- 17. A compound of the formula III
- 18. The compound of claim 17, wherein M is vinyl.
- 19. The compound of claim 17: 1-vinyl-3-aminoimidazolium salt.
- 20. A pharmaceutical composition, comprising a compound of claim 17 and a pharmaceutically acceptable carrier.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a continuation-in-part of co-pending U.S. patent application Ser. No. 09/905,188, filed Jul. 13, 2001, which claims the priority of U.S. Provisional Application Serial No. 60/218,273, filed Jul. 13, 2000; 60/296,435, filed Jun. 6, 2001; 60/259,242, filed Jan. 2, 2001, and 60/259,431, filed Dec. 29, 2000.
[0002] This application is also a continuation-in-part of co-pending U.S. patent Application Ser. No. 10/038,112, filed Dec. 31, 2001, which claims the priority of U.S. Provisional Application Nos. 60/307,418, filed Jul. 24, 2001; 60/296,257, filed Jun. 6 2001; and 60/259,426, filed Dec. 29, 2000.
Provisional Applications (7)
|
Number |
Date |
Country |
|
60296435 |
Jun 2001 |
US |
|
60218273 |
Jul 2000 |
US |
|
60259242 |
Jan 2001 |
US |
|
60259431 |
Dec 2000 |
US |
|
60307418 |
Jul 2001 |
US |
|
60296257 |
Jun 2001 |
US |
|
60259426 |
Dec 2000 |
US |
Continuation in Parts (2)
|
Number |
Date |
Country |
Parent |
09905188 |
Jul 2001 |
US |
Child |
10354952 |
Jan 2003 |
US |
Parent |
10038112 |
Dec 2001 |
US |
Child |
10354952 |
Jan 2003 |
US |