Claims
- 1. A method of treating neuronal diseases in warm-blooded animals which comprises administering to warm-blooded animals an amount of a 2-acylaminopropanol of the formula ##STR4## wherein R.sup.1 is phenyl or cyclohexyl, each of which may be substituted by 1 to 3 same or different substituents selected from the group consisting of alkyl, alkoxy, hydroxy and nitro, or wherein R.sup.1 is alkyl, and n is an integer of 0 to 16 or a pharmaceutically acceptable salt thereof effective for effecting an activity selected from the group consisting of accelerating biosynthesis of glucosphingolipids, accelerating neurite extension and accelerating synapse formation in warm-blooded animals which suffer from neuronal diseases.
- 2. The method of treating neuronal diseases according to claim 1, wherein n of the formula (I) is 6 to 16.
- 3. The method of treating neuronal diseases according to claim 1, wherein R.sup.1 of the formula (I) is a phenyl group.
- 4. The method of treating neuronal diseases according to claim 1, wherein the 2-acylaminopropanol represented by the formula (I) is a L-threo isomer.
- 5. The method of treating neuronal diseases according to claim 4, wherein the 2-acylaminopropanol is a L-threo isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, or a salt thereof.
- 6. The method of claim 1 wherein the daily amount of the compound of Formula I is 0.25 to 200 mg/kg.
Priority Claims (1)
Number |
Date |
Country |
Kind |
5-220518 |
Aug 1993 |
JPX |
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Parent Case Info
This is a continuation-in-part application of PCT Application No. PCT/JP94/01342 of Aug. 12, 1994, an English translation of which was filed on the same day, now abandoned, which is a continuation filed in the United States as application Ser. No. 08/464,683, filed on Aug. 5, 1995, now U.S. Pat. No. 5,707,649 issued on Jan. 13, 1998.
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Date |
Kind |
5041441 |
Radin et al. |
Aug 1991 |
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5707649 |
Inokuchi et al. |
Jan 1998 |
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Entry |
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Continuations (1)
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Number |
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Parent |
464683 |
Aug 1995 |
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