Claims
- 1. A method of preventing cancer in a subject at risk for developing cancer comprising administering to said subject a pharmaceutical composition comprising a therapeutically effective amount of a pharmaceutically acceptable prodrug of a benzi ridazole having the formula:
- 2. A method according to claim 1 wherein the composition comprises a pharmaceutically acceptable prodrug of 2-methoxycarbonylarninobenzimidazole.
- 3. A method according to claim 1 wherein the therapeutically effective amount is from 500 mg/kg body weight to 6000 mg/kg body weight of the benzir nidazole.
- 4. A method according to claim 1 wherein the cancer is colon cancer.
- 5. A method according to claim 1 wherein the cancer is pancreatic cancer.
- 6. A method according to claim 1 wherein the cancer is breast cancer.
- 7. A method according to claim 1 wherein the cancer is lung cancer.
- 8. A method according to claim 1 wherein the cancer is leukemia.
- 9. A method according to claim 1 wherein the cancer is sarcoma.
- 10. A method according to claim 1 wherein the prodrug is micronized.
- 11. A method of inhibiting metastasis of a cancer susceptible to treatment in a subject at risk for metastasis of cancer comprising adminriistering to said subject a pharmaceutical composition comprising a therapeutically effective amount of a pharmaceutically acceptable prodrug of a benzimidazole having the formula:
- 12. A method according to claim 11 wherein the composition comprises a pharmaceutically acceptable prodrug of 2-methoxycarbonylaimnnobenziniidazole.
- 13. A method according to claim 11 wherein the therapeutically effective amount is from 500 mg/kg body weight to 6000 mg/kg body weight of the benzimidazole.
- 14. A method according to claim 11 wherein the cancer is colon cancer.
- 15. A method according to claim 11 wherein the cancer is pancreatic cancer.
- 16. A method according to claim 11 wherein the cancer is breast cancer.
- 17. A method according to claim 11 wherein the cancer is lung cancer.
- 18. A method according to claim 11 wherein the cancer is leukemia.
- 19. A method according to claim 11 wherein the cancer is sarcoma.
- 20. A method according to claim 11 wherein the prodrug is micronized.
CROSS REFERENCE TO RELATED APPLICATIONS
[0001] The present application is a continuation of U.S. Ser. No. 09/374,717, filed Aug. 13, 1999.
Continuations (1)
|
Number |
Date |
Country |
Parent |
09374717 |
Aug 1999 |
US |
Child |
10198334 |
Jul 2002 |
US |