U.S. Ser. No. 07/432,044, Termine, filed Nov. 3, 1989. |
Black, et al., "Urinary excretion of the hydroxypyridinium cross links of collagen in patients with rheumatoid arthritis," Annals of the Rheumatic Diseases, 48:641-644 (1989). |
Seibel, et al., "Urinary Hydroxy-pyridinium Crosslinks Provide Indices of Cartilage and Bone Involvement in Arthritic Diseases," the Journal of Rheumatology, 16:964-970 (1989). |
Baldwin, et al., "Structure of cDNA clones coding for human type II procollagen: the a1 (II) chain is more similar to the a1(I) chain than two other a chains of fibrillar collagens," Biochemistry Journal, 262:521-528 (1989). |
Ala-Kokko, et al., "Structure of cDNA clones coding for the entire preproal(III) chain of human type III procollagen: Differences in protein structure from type I procollagen and conservation of codon preferences," Biochemistry Journal, 260:509-516 (1989). |
Seibel, "Komponenten der extrazllularen Gewebematrix als potentielle `Marker` des Bindegewebs-, Knorpel-und Knochenmetabolismus bei Erkrankungen des Bewegungsapparates," Zeitschrift fur Rheumatologie, 48:6-18 (1989). |
Dodge and Poole, "Immunohistochemical Detection and Immunochemical Analysis of Tpe II Collagen Degradation in Human Normal, Rheumatoid, and Osteoarthritic Articular Cartilages and in Explants of Bovine Articular Cartilage Cultured with Interleukin 1," Journal of Clinical Investigation, 83:647-661 (1989). |
Niemela, "Radioimmunoassays for Type III Procollagen Amino-Terminal Peptides In Humans," Clinical Chemistry, 31:1301-1304 (1985). |
Sangiorgi, et al., "Isolation and partial characterization of the entire human proa1(II) collagen gene," Nucleic Acids Research, 13:2207-2225 (1985). |
Loidl, et al., "Molecular cloning and carboxyl-propertide analysis of human type III procollagen," Nucleic Acids Research, 12:9383-9394 (1984). |
Wu and Eyre, "Identification of Hydroxypyridinium Cross-Linking Sites in Type II Collagen of Bovine Articular Cartilage," Biochemistry, 23:1850-1857 (1984). |
Pierard, et al., "Radioimmunoassay for the Amino-Terminal Sequences of Type III Procollagen in Human Body Fluids Measuring Fragmented Precursor Sequences," Analytical Biochemistry, 141:127-136 (1984). |
Rohde, et al., "Radioimmunoassay for type III procollagen peptide and its application to human liver disease," European Journal of Clinical Investigation, 9:451-459 (1979). |
Russell, R.G.G., et al., "Biochemical Markers of Bone Turnover in Paget's Disease," Metab. Bone Dis. & Rel. Res., 4 & 5:255-262 (1981). |
Drinkwater, B.L., et al., "Bone Mineral Density After Resumption of Menses in Amenorrheic Athletes," JAMA, 256:380-382 (1986). |
Drinkwater, B.L., et al., "Bone Mineral Content of Amenorrheic and Eumenorrheic Athletes," the New England Journal of Medicine, 311:5; 277-281 (1984). |
Fujimoto, D., "Evidence for Natural Existence of Pyridinoline Crosslink in Collagen," Biochemical and Biophysical Research Communications, 93:948-953 (1980). |
Yamauchi, M. et al., "A Comparative Study of the Distribution of the Stable Crosslink, Pyridinoline, in Bone Collagens from Normal, Osteoblastoma, and Vitamin D-Deficient Chicks," Biochemical and Biophysical Research Communications, 102:59-65 (1981). |
Kuboki, Y., et al., "Location of the Intermolecular Crosslinks in Bovine Dentin Collagen, Solubilization with Trypsin and Isolation of Cross-Link Peptides Containing Dihydroxylysinonorleucine and Pyridinoline," Biochemical and Biophysical Research Communications, 102:119-126 (1981). |
Gunja-Smith, Z. and Boucek, R.J., "Collagen cross-linking compounds in human urine," Biochemical Journal, 197:759-762 (1981). |
Tsuchikura, O., et al., "Pyridinoline Fluorescence in Cyanogen Bromide Peptides of Collagen," Biochemical and Biophysical Research Communications, 102:1203-1208 (1981). |
Tsuda, M., et al., "Pyridinoline is a Real Moiety of Collagen," Biochemical and Biophysical Research Communications, 104:1407-1412 (1982). |
Robins, S.P., "An enzyme-linked immunoassay for the collagen cross-link pyridinoline," Biochemical Journal, 207:617-620 (1982). |
Banes, A.J., et al., "Nonmineralized and Mineralized Compartments of Bone: the Role of Pyridinoline in Nonmineralized Collagen," Biochemical and Biophysical Research Communications, 113:975-981 (1983). |
Fujimoto, D., et al., "Analysis of Pyridinoline, a Cross-Linking Compound of Collagen Fibers, in Human Urine," J. Biochem., 94:1133-1136 (1983). |
Eyre, D.R., et al., "Cross-Linking in Collagen and Elastin," Ann. Rev. Biochem., 53;717-748 (1984). |
Light, N. and Bailey, A.J., "Collagen crosslinks: Location of pyridinoline in type I collagen," FEBS 2409, 182:503-508 (1985). |
Wu, J-J. and Eyre, D.R., "Fine Powdering Exposes the Mineral-Protected Collagen of Bone to Protease Digestion," Calcif. Tissue Int., 42:243-247 (1988). |
Fujimoto, D., et al., "Pyridinoline, A Non-Reducible Crosslink of Collagen. Quantitative Determination, Distribution, and Isolation of a Crosslinked Peptide," Chemical Abstracts 89(11):148, (Sep. 11, 1978). |
Black, D., et al., "Quantitative Analysis of the Pyridinium Crosslinks of Collagen in Urine Using Ion-Paired Reversed-Phase High-Performance Liquid Chromatography," Chemical Abstracts 108(21):354, (May 23, 1988). |
Fujimoto, D., et al., "Analysis of Pyridinoline, A Cross-Linking Compound of Collagen Fibers, in Human Urine," Chemical Abstracts 99(19):446-447, (Nov. 7, 1983). |
Macek, J., et al., "Determination of Collagen Degradation Products in Human Urine in Osteoarthrosis," Chemical Abstracts 108(3):299, (Jan. 18, 1988). |
Eyre, D.R., et al., "Quantitation of Hydroxypyridinium Crosslinks in Collagen by High-Performance Liquid Chromatography," Analytical Biochemistry, 137:380-388 (1984). |
Robins, S.R., et al., "Measurement of the cross linking compound, pyridinoline, in urine as an index of collagen degradation in joint disease," Annals of the Rheumatic Diseases, 45:969-973 (1986). |
Bernard, M.P., et al., "Nucleotide Sequences of Complementary Deoxyribonucleic Acids for the Proal Chain of Human Type I Procollagen. Statistical Evaluation of Structures that are Conserved During Evolution," Biochemistry, 22:5213-5223 (1983). |
Goldstein, D., et al., "Simultaneous Measurement of DOPA, DOPAC, and Catecholamines in Plasma by Liquid Chromatography with Electrochemical Detection," ESA Review, vol. II, No. 1, pp. 2-11 (1986). |
Chu, M-L., et al., "Human proa1(I) collagen gene structure reveals evolutionary conservation of a pattern of introns and exons," Nature 310(26):337-340 (1984). |
Robins, S.P., et al., "Measurement of Hydroxypyridinium Crosslinks of Collagen as an Index of Bone Matrix Degradation," An Abstract of a Paper, Lake Garda, Italy (1987). |
Kang, A.H. and Gross, J., "Amino Acid Sequence of Cyanogen Bromide Peptides from the Amino-Terminal Region of Chick Skin Collagen," Biochemistry 9:796-804 (1970). |
Highberger, J.H., et al., "The Amino Acid Sequence of Chick Skin Collagen a1-CB7," Biochemistry 14(13):2872-2881 (1975). |
Fietzek, P.P. and Kuhn, K., "The Covalent Structure of Collagen: Amino Acid Sequence of the N-Terminal Region of a2-CB5 from Rat Skin Collagen," FEBS Letters 36(3):289-291 (1973). |
Dixit, S.N., et al., "Covalent Structure of Collagen: Amino Acid Sequence of a2-CB5 of Chick Skin Collagen Containing the Animal Collagenase Cleavage Site," Biochemistry, 18:3416-3422 (1979). |
Dakkak, et al., "Modifications de l'hydroxyprolinurie peptidique au cours de la maladie de Paget et des osteomes," Ann. Biol. Clin. 37:195-200 (1979). |
Teitsson, et al., "Urinary excretion of pyridinium metabolites in a patient with Paget's Disease: new markers for collagen break-down," Abstracts, Scottish Society for Experimental Medicine, May 13, 1988. |
Eyre, et al., "Collagen cross-linking in human bone and articular cartilage: Age-related changes in the content of mature hydroxypyridinium residues," Biochem. J. 252:495-500 (1988). |
Whittle, et al., "Biochemical investigation of possible lesions in human aorta that predispose to dissecting aneurysms: pyridinoline crosslinks," Cardiovascular Research 21:161-168 (1987). |
Gunja-Smith, Z., "An Enzyme-Linked Immunosorbent Assay to Quantitate the Elastin Crosslink Desmosine in Tissue and Urine Samples," Analytical Biochemistry 147:258-264 (1985). |
Schuppan, et al., "Radioimmunoassay for the Carboxy-terminal Cross-linking Domain of Type IV (Basement Membrane) Procollagen in Body Fluids," J. Clin. Invest. 78:241-248 (Jul. 1986). |
Eyre, D., "Collagen Cross-Linking Amino Acids," In: Methods in Enzymology, vol. 144, pp. 115-139, Academic Press, Inc., 1987. |
Eyre, et al., "Identification of urinary peptides derived from cross-linking sites in bone collagen in Paget's Disease," Journal of Bone and Mineral Research, 3, Supp. 1 (Jun. 1988). |
Eyre, et al., "Reducible Crosslinks in Hydroxylysine-Deficient Collagens of a Heritable Disorder of Connective Tissue," Proc. Nat. Acad. Sci. USA 69(9):2594-2598 (Sep. 1972). |
Eyre, et al., "Evidence for a previously undetected sequence at the carboxy-terminus of the a1 chain of chicken bone collagen," Biochemical and Biophysical Research Communications 48(3):720-726 (1972). |
Eyre, et al., "The distribution of crosslinking aldehydes in a1 and a2 chains of chicken bone collagen," Biochimica et Biophysica Acta 278:206-210 (1972). |
Eyre, et al., "Evidence for intramolecular crosslinks in chicken bone collagen: the isolation of peptides containing allysine aldol," Biochimica et Biophysica Acta 295:301-307 (1973). |
Eyre, et al., "Analysis of a crosslinked peptide from calf bone collagen: evidence that hydroxylysyl glycoside participates in the crosslinks," Biochemical and Biophysical Research Communications 52(2): 633-671 (1973). |
Eyre, et al., "Isolation of crosslinked peptides from collagen of chicken bone," Biochem J. 135:393-403 (1973). |
Eyre, et al., "The hydroxypyridinium crosslinks of skeletal collagens: their measurement, properties and a proposed pathway of formation," Biochemical and Biophysical Research Communications 92(2): 403-410 (1980). |
Walters, et al., "Collagen Crosslinks in Human Dentin: Increasing Content of Hydroxypyridinium Residues with Age," Calcif. Tissue Int. 35:401-405 (1983). |
Wu, et al., "Identification of Hydroxypyridinium Cross-Linking Sites in Type II Collagen of Bovine Articular Cartilage," Biochemistry 23:1850-1857 (1984). |
Wu, et al., "Cartilage type IX collagen is cross-linked by hydroxypyridinium residues," Biochemical and Biophysical Research Communications 123(3):1033-1039 (1984). |
Eyre, et al., "Collagen type IX: evidence for covalent linkages to type II collagen in cartilage," FEB 220(2):337-341 (1987). |
Beardsworth, et al., "Changes with Age in the Urinary Excretion of Lysyl-and Hydroxylysylpyridinoline, Two New Markers of Bone Collagen Turnover," Journal of Bone and Mineral Research 5(7);671-676 (1990). |
Eyre, D.R., "Collagen: Molecular Diversity in the Body's Protein Scaffold," Science 207:1315-1322 (1980). |
Eyre, D.R., "Collagen Stability Through Covalent Crosslinking," in: Pearson, et al., eds. Advances in Meat Research, vol. 4, Collagen as a Food. New York: Van Nostrand Reinhold, 1987. |
Eyre, D.R., "Crosslink maturation in bone collagen," In: Veis, A., ed. the Chemistry and Biology of Mineralized Connective Tissues, Elsevier North Holland, Inc., 1981. |
Eyre, D.R., "Collagen cross-linking," In: Akeson, W.H. et al., eds., AAOS: Symposium on Heritable Disorders of Connective Tissue, St. Louis: C.V. Mosby, 1982, pp. 43-58. |
Eyre, et al., "Studies on the molecular diversity and cross-linking of cartilage collagen," In: Peyron, J.G., ed. Osteoarthritis: Current Clinical and Fundamental Problems, Paris, France: CIBA-GEIGY, 1984, pp. 117-122. |
Delmas, Pierre D., "Biochemical Markers of Bone Turnover for the Clinical assessment of Metabolic Bone Disease," Endocrinology and Metabolism Clinics of North America, 19(1) (Mar. 1990). |
Uebelhart, et al., "Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease" Bone and Mineral, 8:87-96 (1990). |
Uebelhart, et al. "Effect of Menopause and Hormone Replacement Therapy on the Urinary Excretion of Pyridinium Cross-Links," Journal of Clinical Endocrinology and Metabolism, 72(2):367-373 (1991). |
Black, D., Duncan, A. and Robins, S.P., "Quantitative analysis of the Pyridinium Crosslinks of Collagen in Urine Using Ion-Paired Reversed-Phase High-Performance Liquid Chromatography," Analytical Biochemistry 169:197-203 (1988). |
Davison, et al., "The Effects of Acetic Acid on Collagen Cross-Link," Connective Tissue Research 1:205-216 (1972). |
Fujimoto and Moriguchi, "Pyridinoline, a non-reducible crosslink of collagen," J. Biochem. 83:863-867 (1978). |
Macek and Adam, "Determination of collagen degradation products in human urine in osteoarthrosis," Z. Rheumatol. 46:237-240 (1987). |
Eyre, D.R., "Evidence for intramolecular cross-links in chicken bone collagen: Isolation of peptides containing allysine aldol," Chem. Abstracts, 78(13):81202c (1973). |
Kuhn, Klaus, "Chemical Properties of Collagen," In: Immunochemistry of the Extracellular Matrix, vol. I, pp. 1-29, CRC Press, Inc., 1982. |
Robins, "Cross-linking of collagen," Biochem. J. 215:167-173 (1983). |
Robins and Duncan, "Cross-linking of collagen," Biochem. J. 215:175-182 (1983). |
Robins and Duncan, "Pyridinium crosslinks of bone collagen and their location in peptides isolated from rat femur," Biochem. et Biophys. Acta 914:233-239 (1987). |
Henkel, Werner, Glanville, Robert W., and Oreifendorf, Dieter, "Characterisation of a type-I collagen trimeric cross-linked peptide from calf aorta and its cross-linked structure," Eur. J. Biochem 165:427-436, 1987. |
Kuivaniemi, et al., "Structure of a full-length cDNA clone for a prepro.alpha.(I) chain of human type I procollagen," Biochem. J. 252:633-640 (1987). |
Hanson, D.A., et al., "A specific immunoassay for monitoring human bone resorption: Quantitation of type I collagen cross-linked N-telopeptides in urine," Journal of Bone & Mineral Research 7(11):1251-1258 (1992). |
Bernard, M.P. et al., Nucleotide sequences of complementary deoxyribonucleic acids for the proa.sub.1 chain of human type I procollagen; statistical evaluation of structures that are conserved during evolution, Biochemistry 22:5213-5223 (1983). |
Del Pozo, A.M., et al., "Binding of 1-Anilinonsphthalene-8-Sulfonic Acid to Type I Collagen," Int. J. Peptide Protein Res. 28:329-358 (1983). |
Robins, S.P., Analysis of the Crosslinking Components in Collagen and Elastin, Methods of Biochemical Analysis 28:329-379 (1982). |
Fujimoto, D., Isolation and Characterization of a Fluorescent Material in Bovine Achilles Tendon Collagen, Biochemical and Biophysical Research Communications 76(4):1124-1129 (1977). |
Seibel, et al., "Urinary Hydroxy-pyridinium Crosslinks Provide Indices of Cartilage and Bone Involvement in Arthritic Diseases," The Journal of Rheumatology, 16(7):964-970 (1989). |
Click and Bornstein, Isolation and Characterization of the Cyanogen Bromide Peptides from the .alpha.1 and .alpha.2 Chains of Human Skin Collagen, Biochemistry 9(24):4699-4706 (1970). |
Kruger-Franke, M., et al., "Pyridinolinhaltige Kollagenbruchstucke im Urin bei Coxarthrose," Z. Rheumatol. 50:323-327 (1991). |
Dickson et al., Analysis of the promoter region and the N-propeptide domain of the human pro.alpha.2(I) collagen gene, Nucleic Acids Research 13(10):3427-3438 (1985). |
Abbiati et al., Monitoring of free and total urinary pyridinoline and deoxpyridinoline in healthy volunteers: sample relationships between 24-h and fasting early morning urine concentrations, Bone and Mineral, 21:9-19 (1993). |
Fujimoro, E., "Ultraviolet light-and ozone-induced changes in pyridinoline, a trisubstituted 3-hydroxypyridinium crosslink of collagen," Biochimica et Biophysica Acta 828:104-106 (1985). |
Sakura et al., "Photolysis of pyridinoline, a cross-linking amino acid of collagen, by ultraviolet light," Can. J. Biochem. 60:525-529 (1982). |
Sakura et al., "Electrochemical behavior of pyridinoline, a crosslinking amino acid of collagen," J. Biochem. 89:1541-1546 (1981). |
Koob et al., Detection and Photolysis of Hydroxypyridinium Crosslinks in Cartilage Collagen In Situ, Orthopaedic Transactions 7(2):251-252 (1983). |
Rosmalen et al., "Light sensitivity of deoxypyridinoline: implications for the collection of urine," J.B.M.R. 9(Suppl. 1):B421 (1994). |
Baurain et al., "Photolysis of desmosine and isodesmosine by ultraviolet light," Eur. J. Biochem 67:155-164 (1976). |
Blumsohn et al., "Effect of light and .gamma.-irradiation on pyridinolines and telopeptides of type I collagen in urine," Clinical Chemistry 41(8):1195-1197 (1995). |
Becker, U., Timpl, R., and Kuhn, K., "Carboxyterminal Antigenic Determinants of Collagen from Calf Skin: Localization within Discrete Regions of the Nonhelical Sequences," Eur. J. Biochem. 28:221-231 (1972). |
Lane et al., "Immunofluorescent Localization of Structural Collagen Types in Endochondral Fracture Healing," Orthopaedic Transactions, VI(2):236 (1982). |
Kuhn, K., "The Classical Collagens: Types I, II, and III," In: Structure and Function of Collagen Types (1987). |
Rauterberg, J., "The C-Terminal Non-Helical Portion of the Collagen Molecule," Clin. Ortho. Rel. Res. 97:196-212 (1973). |
Davril et al., "Photolysis of crosslinked peptides from elastin of porcine aorta," FEBS Letters, 98(1):128-134 (1979). |
Otter et al., Type I Collagen .alpha.-1 Chain C-Telopeptide: Solution Structure Determined by 600-MHz Proton NMR Spectroscopy and Implications for Its Role in Collagen Fibrillogenesis, Biochemistry, 27:3560-3567 (1988). |
van Hoek, et al., A Novel Polyclonal Antibody Against Deoxy-pyridinoline to be Used in a Radioimmunoassay, Second Workshop on Bisphosphonates, Davos, Switzerland, Apr. 14-16, 1994. |
Fuller, F. and Boedtker, H., "Sequence Determination and Analysis of the 3' Region of Chicken Pro-.alpha.1(I) and Pro-.alpha..sub.-- (I) Collagen Messenger Ribonucleic Acids Including the Carboxy-Terminal Propeptide Sequences," Biochemistry 20:996-1006 (1981). |
Rosmalen et al., Light Sensitivity of Deoxypyridinoline: Implications for the Collection of Urine, Presented at the Sixteenth Annual Meeting of the American Society of Bone and Mineral Research, Sep. 9-13, 1994. |
Gunja-Smith & Boucek, "Desmosines in human urine," Biochem. J. 193:915-918 (1981). |
Tellerova et al., "Determination of larger uinary peptides in osteoarthrosis by high-performance liquid chromatography," Scand J Rheumatology 15:52-56 (1986). |
Adam, M. and Z. Deyl, "Altered expression of collagen phenotype in osteoarthrosis," Clinica Chimica Acta., 133:25-32 (1983). |
Johnstone et al., Immunochemistry in Practice, Blackwell Scientific Publications, Oxford, U.K., 1987, pp. 48-65. |