Method of detecting toxic substance

Information

  • Patent Application
  • 20040248126
  • Publication Number
    20040248126
  • Date Filed
    May 27, 2004
    20 years ago
  • Date Published
    December 09, 2004
    19 years ago
Abstract
Biology-based processes for detecting toxic substances are provided. The processes comprise detecting mRNA that is expressed in the presence of toxic substances by a cell comprising a yeast gene as followed, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof.
Description


FILED OF THE INVENTION

[0001] This invention relates to biology-based processes for detecting toxic substances, and specifically to processes for detecting toxic substances which comprises detecting mRNA that is transcribed in the presence of test materials by a particular gene from yeast.



BACKGROUND ART

[0002] Environmental chemical fate search has been conducted every year for 24 years from 1974 through 1998 by Environment Agency, and revealed that about 40% of 775 chemical substances that have been searched so far are emitted into the environment. Chemical substances that are industrially produced at the present in Japan are estimated about 50,000, and the production scale and the kinds of chemical substances are increasing year by year. It is known that chemical substances that are accidentally produced by water treatment with chlorine and incineration pollute the environment. Although such facts allow us to predict that there are a large number of chemical substances that have been accumulated in the environment, it is extremely difficult to search and examine individually the all chemical substances.


[0003] Conventional bioassays (approaches to evaluate the harmful effects on biological materials on the basis of their responses) wherein inhibited growth and particular biological responses in individuals and cells of fishes, daphnia and shellfish are used as indicators make it possible to determine the presence or absence of the toxicity of chemical substances in the environment, but neither possible to evaluate the characters nor origins of the toxicity. The evaluation methods based on the activity of nitrite-forming bacteria or nitrate-forming bacteria (Japanese Patent Publication (kokai) No. 123705/1994, Japanese Patent Publication (kokai) No. 2000-206087) and the activity of iron bacteria have been proposed, and devices such as Acute toxiciants monitor (Fuji Electric Corporate Research and Development, Ltd. Japan) are marketed in Japan. In foreign countries, the devices for evaluation based on emission intensity of luminous bacteria are commercially available (MICROTOX, azur, Co., USA; LUMIS, drlange, Co. Germany). However, those devices still involve conventional bioassays, and never provide any detailed information of toxic chemical substances.


[0004] In Japan, the risk control of chemical substances is reconsidered every time a chemical substance pollution is newly found, and official regulations and self-imposed regulations are combined to organize the system for risk control. However, any system has not been yet organized that could quickly respond to the present complicated and diversified conditions including accidental productions and environmental emission of toxic chemical substance as typified by trihalomethane and dioxin. Animal experiments as used in the method for evaluation of toxic substance of “Law Concerning Examination and Manufacture, etc. of Chemical Substances” are expensive and time-consuming, and are not accepted across the world. Although, as such, the control system has been continuously discussed, it has not been successfully accomplished because there is no way to dissolve the problem. Thus, a method for detect readily chemical substances occurring in the environment is desired.



DISCLOSURE OF THE INVENTION

[0005] The inventors of the present application found that a toxic substance induces the expression of mRNA from particular yeast genes, and accomplished the present invention.


[0006] Specifically, the invention of the present application relates a process for detecting a toxic substance, which comprises detecting mRNA that is expressed in the presence of a test material by a cell comprising a yeast gene that is selected from a group consisting of the following, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof:


[0007] YBR072W, YCR102C, YCR107W, YDL218W, YDL243C, YDR453C, YDR533C, YFL014W, YFL056C, YFL057C, YGR110W, YJR155W, YKL071W, YKR076W, YLL060C, YLR460C, YMR090W, YNL331C, YNL332W, YNL335W, YOL150C, YOL165C, YPL171C, YPR167C, YBL048W, YBL064C, YBL107C, YBR008C, YBR173C, YBR256C, YBR296C, YDL021W, YFL022C, YFL024C, YFL061W, YGL121C, YGL158W, YGR043C, YHR029C, YHR112C, YHR139C, YHR179W, YHR209W, YIR030C, YJR010W, YJR048W, YKL001C, YKL107W, YKR075C, YKR097W, YLL056C, YLR297W, YLR303W, YML087C, YMR096W, YNL274C, YOL151W, YOR226C, YOR338W, YOR391C, YPL280W, YDR406W, YJL153C, YLR346C, YOR049C, YOR153W, YPL088W, YAL034C, YDL124W, YDL174C, YDR476C, YGL156W, YGR035C, YGR157W, YGR213C, YGR281W, YGR284C, YHL047C, YHR043C, YHR044C, YHR054C, YJR073C, YKL165C, YLR008C, YMR315W, YNL211C, YOL031C, YOL101C, YOR303W, YAL005C, YAR031W, YBL005W-A, YBL022C, YBL041W, YBL049W, YBL075C, YBL078C, YBR062C, YBR169C, YBR294W, YCL020W, YCL035C, YCL043C, YCL050C, YCL057W, YCR012W, YCR013C, YCR060W, YDL007W, YDL027C, YDL097C, YDL110C, YDL126C, YDL169C, YDR070C, YDR155C, YDR158W, YDR204W, YDR210W, YDR214W, YDR258C, YDR313C, YDR368W, YDR435C, YER012W, YER037W, YER091C, YER103W, YFL044C, YFR003C, YFR010W, YFR020W, YFR024C, YFR044C, YFR053C, YGL006W, YGL048C, YGL062W, YGL141W, YGL157W, YGL163C, YGL180W, YGL184C, YGR010W, YGR028W, YGR032W, YGR048W, YGR124W, YGR135W, YGR142W, YGR161C, YGR192C, YGR197C, YGR201C, YGR212W, YGR231C, YGR244C, YGR254W, YGR268C, YHL030W, YHR016C, YHR018C, YHR055C, YHR087W, YHR166C, YIL160C, YIR017C, YJL034W, YJL048C, YJL052W, YJL144W, YJL163C, YJR009C, YJR069C, YJR074W, YJR130C, YJR149W, YKL065C, YKL073W, YKL103C, YKL142W, YKL210W, YKL218C, YKR011C, YKR018C, YKR046C, YKR049C, YLL024C, YLL026W, YLR027C, YLR080W, YLR107W, YLR121C, YLR132C, YLR133W, YLR155C, YLR158C, YLR161W, YLR195C, YLR217W, YLR328W, YLR336C, YLR345W, YLR370C, YLR423C, YML004C, YML092C, YML128C, YML130C, YML131W, YMR040W, YMR118C, YMR214W, YMR251W, YMR297W, YMR322C, YNL036W, YNL055C, YNL071W, YNL094W, YNL134C, YNL155W, YNL160W, YNL239W, YNL241C, YOL005C, YOR020C, YOR027W, YOR037W, YOR059C, YOR120W, YOR134W, YOR152C, YOR173W, YOR289W, YOR362C, YPL240C, YPR030W, YAL008W, YAL023C, YAL060W, YAL062W, YAR009C, YBL101C, YBR006W, YBR046C, YBR052C, YBR053C, YBR056W, YBR099C, YBR137W, YBR139W, YBR149W, YBR170C, YBR177C, YBR203W, YBR207W, YBR212W, YBR239C, YBR284W, YBR293W, YCL018W, YCL033C, YCL040W, YCL049C, YCR062W, YCR067C, YCR082W, YDL010W, YDL020C, YDL024C, YDL054C, YDL095W, YDL100C, YDL115C, YDL144C, YDL198C, YDL223C, YDL245C, YDL246C, YDR001C, YDR032C, YDR058C, YDR072C, YDR127W, YDR168W, YDR169C, YDR188W, YDR231C, YDR261C, YDR264C, YDR272W, YDR293C, YDR304C, YDR330W, YDR403W, YDR411C, YDR427W, YDR436W, YDR497C, YDR511W, YDR516C, YDR519W, YDR545W, YEL012W, YEL030W, YER004W, YER009W, YER021W, YER035W, YER053C, YER079W, YER094C, YER096W, YER125W, YER158C, YER163C, YER175C, YER177W, YER178W, YER185W, YFL006W, YFL010C, YFL016C, YFL029C, YFL030W, YFL031W, YFL032W, YFL038C, YFL041W, YFR004W, YFR047C, YFR050C, YFR052W, YGL011C, YGL013C, YGL037C, YGL047W, YGL053W, YGL091C, YGL094C, YGL127C, YGL150C, YGL199C, YGL207W, YGL248W, YGR008C, YGR037C, YGR055W, YGR101W, YGR130C, YGR154C, YGR194C, YGR221C, YGR232W, YGR248W, YGR253C, YGR256W, YHL008C, YHR027C, YHR053C, YHR057C, YHR111W, YHR138C, YHR161C, YHR164C, YHR169W, YHR174W, YHR176W, YHR199C, YIL010W, YIL034C, YIL041W, YIL045W, YIL087C, YIL107C, YIL142W, YIL155C, YIR034C, YIR036C, YIR037W, YIR038C, YIR039C, YJL001W, YJL031C, YJL035C, YJL053W, YJL057C, YJL066C, YJL068C, YJL082W, YJL099W, YJL102W, YJL151C, YJL152W, YJL161W, YJL164C, YJL171C, YJL172W, YJL210W, YJL219W, YJR008W, YJR045C, YJR046W, YJR106W, YJR117W, YJR137C, YKL007W, YKL026C, YKL035W, YKL091C, YKL104C, YKL117W, YKL145W, YKL146W, YKL151C, YKL152C, YKL153W, YKL193C, YKL195W, YKL213C, YKL215C, YLL028W, YLL039C, YLL058W, YLR054C, YLR103C, YLR120C, YLR136C, YLR149C, YLR152C, YLR178C, YLR259C, YLR299W, YLR324W, YLR327C, YLR348C, YLR350W, YLR356W, YLR362W, YLR387C, YLR429W, YML054C, YML070W, YML100W, YML117W, YML125C, YMR004W, YMR008C, YMR009W, YMR020W, YMR067C, YMR089C, YMR097C, YMR102C, YMR105C, YMR107W, YMR152W, YMR180C, YMR184W, YMR191W, YMR219W, YMR271C, YMR275C, YMR295C, YMR314W, YMR316W, YNL006W, YNL007C, YNL012W, YNL044W, YNL045W, YNL074C, YNL092W, YNL093W, YNL104C, YNL115C, YNL156C, YNL231C, YNL234W, YNL237W, YNL281W, YNL305C, YNL333W, YNR010W, YNR019W, YNR033W, YNR059W, YNR068C, YNR069C, YOL032W, YOL036W, YOL047C, YOL071W, YOL082W, YOL083W, YOL117W, YOL119C, YOL126C, YOL131W, YOL153C, YOL162W, YOL163W, YOL164W, YOR019W, YOR035C, YOR036W, YOR099W, YOR117W, YOR124C, YOR130C, YOR132W, YOR157C, YOR185C, YOR197W, YOR259C, YOR261C, YOR273C, YOR288C, YOR332W, YOR336W, YOR347C, YPL017C, YPL087W, YPL106C, YPL109C, YPL149W, YPL154C, YPL196W, YPL206C, YPL222W, YPR023C, YPR024W, YPR026W, YPR067W, YPR103W, YPR108W, YPR151C, YAL012W, YBR029C, YBR222C, YCL009C, YCL027W, YCL064C, YCR098C, YDL222C, YDR055W, YDR077W, YDR502C, YEL001C, YEL042W, YER026C, YER106W, YGR136W, YGR138C, YHR137W, YHR142W, YIL023C, YIL153W, YJL073W, YJR004C, YJR054W, YKL039W, YKL086W, YKL163W, YKR091W, YLR109W, YLR194C, YLR250W, YMR095C, YMR189W, YNL106C, YNL169C, YNL322C, YOR181W, YOR198C, YOR208W, YOR247W, YPL089C, YAL038W, YAL053W, YBR023C, YBR214W, YBR295W, YCR048W, YDL072C, YDL204W, YDR085C, YDR098C, YDR259C, YDR380W, YDR388W, YDR391C, YDR432W, YDR481C, YDR510W, YER069W, YGL022W, YGL126W, YGL209W, YGL255W, YGR189C, YGR282C, YHL035C, YHR030C, YIL022W, YIL024C, YIL117C, YIL123W, YIL140W, YIL154C, YJL088W, YJL108C, YJL149W, YJL159W, YJL186W, YJR148W, YKL096W, YLR180W, YLR273C, YLR300W, YLR307W, YLR378C, YLR391W, YMR094W, YMR104C, YMR276W, YMR296C, YNL190W, YNL208W, YNL300W, YNR064C, YOL013C, YOL058W, YOR248W, YOR355W, YPL052W, YPL163C, YPR079W, YAR028W, YBR146W, YBR183W, YCL038C, YCR071C, YDL008W, YDR019C, YDR031W, YDR115W, YDR486C, YER038C, YER130C, YFL054C, YGL136C, YGR146C, YGR207C, YHL040C, YIL167W, YJL020C, YKR039W, YLR031W, YLR205C, YMR072W, YMR140W, YMR173W, YMR195W, YMR226C, YNL037C, YNR002C, YOL143C, YOR136W, YOR215C, YOR382W, YOR383C, YPL054W, YPL271W, YPR127W, YAL044C, YAL054C, YAR010C, YAR027W, YAR071W, YBL001C, YBL043W, YBL057C, YBR014C, YBR024W, YBR035C, YBR068C, YBR111C, YBR116C, YBR147W, YBR168W, YBR246W, YBR273C, YCR004C, YCR021C, YCR037C, YCR088W, YDL022W, YDL128W, YDL238C, YDR003W, YDR009W, YDR033W, YDR084C, YDR104C, YDR270W, YDR315C, YDR340W, YDR357C, YDR358W, YDR396W, YDR405W, YDR410C, YDR434W, YDR482C, YDR487C, YDR520C, YDR534C, YDR539W, YEL011W, YEL065W, YEL066W, YER039C, YER044C, YER067W, YER080W, YER107C, YFL020C, YFL028C, YFL043C, YFR015C, YGL001C, YGL008C, YGL068W, YGL073W, YGL104C, YGL113W, YGL154C, YGL167C, YGL229C, YGL242C, YGL249W, YGL253W, YGR052W, YGR060W, YGR065C, YGR106C, YGR111W, YGR220C, YGR257C, YHL023C, YHL048W, YHR004C, YHR037W, YHR071W, YHR092C, YHR190W, YIL007C, YIL033C, YIL070C, YIL088C, YIL111W, YIR002C, YIR016W, YIR035C, YIR043C, YJL012C, YJL083W, YJL089W, YJL116C, YJL131C, YJL132W, YJL196C, YJR061W, YJR086W, YJR142W, YJR161C, YKL008C, YKL013C, YKL041W, YKL067W, YKL138C, YKL139W, YKL150W, YKL175W, YKR006C, YKR014C, YKR070W, YLL023C, YLR023C, YLR093C, YLR118C, YLR142W, YLR225C, YLR241W, YLR251W, YLR252W, YLR270W, YML030W, YML110C, YMR021C, YMR027W, YMR148W, YMR181C, YMR262W, YMR272C, YMR298W, YNL011C, YNL130C, YNL214W, YNL259C, YOL129W, YOR042W, YOR052C, YOR137C, YOR149C, YOR165W, YOR270C, YOR285W, YOR367W, YPL018W, YPL156C, YPL186C, YPL203W, YPL216W, YPL255W, YPR006C, YPR073C, YPR098C, YBR050C, YBR145W, YBR299W, YDR518W, YEL020C, YFL062W, YGL039W, YGL134W, YJL217W, YJR159W, YLR126C, YNL249C, YNL284C, YNL336W, YOL157C, YOR344C, YOR381W, YPL265W, YPR124W, YBR074W, YBR109C, YBR126C, YBR201W, YCR005C, YDL248W, YDR041W, YDR105C, YDR268W, YDR452W, YEL075C, YER046W, YER050C, YER136W, YER159C, YGL250W, YGR019W, YGR042W, YGR053C, YGR066C, YGR247W, YGR255C, YGR295C, YHL044W, YHR145C, YIL058W, YIL065C, YIL083C, YIL098C, YIL172C, YJL030W, YJL185C, YJL213W, YJR029W, YJR099W, YJR122W, YJR125C, YKL190W, YKR020W, YLL025W, YLL051C, YLR043C, YLR090W, YLR100W, YLR108C, YLR290C, YML068W, YMR051C, YMR139W, YMR178W, YMR193W, YNL015W, YNL079C, YNL122C, YNL223W, YNL285W, YNL293W, YNR007C, YNR035C, YNR061C, YOL016C, YOL104C, YOR220W, YOR221C, YOR374W, YPL123C, YPR077C, YPR107C, YPR147C, YBR093C, YBR196C, YEL041W, YEL047C, YER023W, YER119C, YFL055W, YGR209C, YIL124W, YKL187C, YLL055W, YMR318C, YOL152W, YAL007C, YBR067C, YBR115C, YBR285W, YBR292C, YDL043C, YDL123W, YDL131W, YDL168W, YDL212W, YDR056C, YDR132C, YDR154C, YDR183W, YDR216W, YDR253C, YDR295C, YDR494W, YDR513W, YEL072W, YER045C, YER061C, YER181C, YFL052W, YFL058W, YFR030W, YGL089C, YGL096W, YGL114W, YGL193C, YGL202W, YGL204C, YGL259W, YGR006W, YGR070W, YGR088W, YHL034C, YHL036W, YHR048W, YHR104W, YHR163W, YIL060W, YIL136W, YIR024C, YJL036W, YJL045W, YJL060W, YJL101C, YJL155C, YJR085C, YJR109C, YJR156C, YKL070W, YKL161C, YKL221W, YKR071C, YLL009C, YLL050C, YLR092W, YLR145W, YLR156W, YLR163C, YLR220W, YLR280C, YLR311C, YLR390W, YML116W, YMR034C, YMR038C, YMR081C, YMR250W, YNL240C, YNL260C, YNL277W, YNR074C, YOL044W, YOL084W, YOL147C, YOL159C, YOR184W, YOR228C, YOR255W, YPL223C, YPR160W, YDL182W, YBR047W, YBR054W, YBR291C, YDR069C, YER124C, YER131W, YGR044C, YIL094C, YKR007W, YMR240C, YNR050C, YOR007C, YAL015C, YBL065W, YBR105C, YBR182C, YBR186W, YBR244W, YBR272C, YCL069W, YDL025C, YDL059C, YDL085W, YDL113C, YDL244W, YDR018C, YDR054C, YDR202C, YDR223W, YDR350C, YDR353W, YDR374C, YDR512C, YEL052W, YEL070W, YER098W, YFR017C, YGL046W, YGL067W, YGL098W, YGL117W, YGL146C, YGL240W, YGR011W, YGR067C, YGR133W, YGR153W, YGR223C, YHR116W, YHR124W, YIL097W, YIL168W, YJL103C, YJL221C, YJR036C, YJR095W, YKL085W, YKL133C, YKL162C, YKL188C, YKL217W, YKR061W, YKR105C, YLL062C, YLR174W, YLR216C, YLR247C, YLR260W, YLR267W, YLR389C, YML007W, YMR041C, YMR177W, YMR253C, YNL009W, YNL117W, YNL128W, YNL183C, YNR073C, YOL133W, YOL158C, YOR133W, YOR225W, YOR227W, YPL161C, YPL166W, YPL202C, YPL224C, YPR015C, YPR086W, YPR201W, YAL061W, YAL067C, YAR007C, YBL033C, YBL056W, YBL086C, YBR026C, YBR073W, YBR101C, YBR117C, YBR123C, YBR213W, YBR269C, YBR280C, YCR036W, YDL132W, YDL149W, YDL200C, YDL234C, YDL242W, YDR099W, YDR177W, YDR256C, YDR392W, YDR394W, YDR531W, YEL071W, YER014W, YER042W, YER090W, YER184C, YFL059W, YFR042W, YFR046C, YFR049W, YGL026C, YGL058W, YGL185C, YGL227W, YGL252C, YGL254W, YGR089W, YGR112W, YGR134W, YGR276C, YHL019C, YHR012W, YHR017W, YHR028C, YHR106W, YHR109W, YHR156C, YIL036W, YIL046W, YIL143C, YIL152W, YIL159W, YIL164C, YJL071W, YJL094C, YJL154C, YJR056C, YJR072C, YJR110W, YJR139C, YKL025C, YKL034W, YKL064W, YKL171W, YKL196C, YKR012C, YKR068C, YKR069W, YLL001W, YLL057C, YLL061W, YLR064W, YLR070C, YLR099C, YLR144C, YLR157C, YLR160C, YLR164W, YLR364W, YLR421C, YML032C, YML042W, YML112W, YML118W, YMR114C, YMR115W, YMR258C, YNL181W, YNL191W, YNL212W, YNL213C, YNL250W, YNL265C, YNL312W, YNR032W, YOL038W, YOL049W, YOL064C, YOR088W, YOR155C, YOR257W, YOR265W, YOR377W, YOR386W, YPL031C, YPL113C, YPL124W, YPL151C, YPL249C, YPL260W, YPL274W, YPR048W, YPR061C, YPR093C, YPR125W, YPR158W, YPR168W, YPR169W, YPR174C, YPR180W, YPR193C, YPR200C, YAL014C, YAL017W, YAL049C, YBL019W, YBL058W, YBR001C, YBR013C, YBR018C, YBR037C, YBR045C, YBR051W, YBR063C, YBR128C, YBR129C, YBR204C, YBR241C, YBR255W, YBR281C, YCL044C, YCL055W, YCR014C, YCR019W, YCR024C, YCR105W, YDL065C, YDL089W, YDL143W, YDL173W, YDL193W, YDL197C, YDL206W, YDL230W, YDL233W, YDR040C, YDR071C, YDR078C, YDR109C, YDR140W, YDR194C, YDR212W, YDR221W, YDR257C, YDR271C, YDR287W, YDR294C, YDR316W, YDR329C, YDR338C, YDR369C, YDR421W, YDR425W, YDR485C, YDR488C, YDR504C, YDR505C, YDR506C, YDR515W, YEL005C, YEL037C, YEL044W, YER017C, YER048C, YER052C, YER078C, YER089C, YER092W, YER100W, YER162C, YER182W, YFL021W, YFL042C, YFR045W, YFR051C, YFR056C, YGL040C, YGL041C, YGL045W, YGL057C, YGL093W, YGL105W, YGL125W, YGL166W, YGL181W, YGL183C, YGL215W, YGL216W, YGL221C, YGL223C, YGR007W, YGR029W, YGR155W, YGR156W, YGR186W, YGR198W, YGR210C, YGR211W, YGR237C, YGR250C, YGR258C, YGR266W, YGR270W, YGR274C, YGR277C, YHL021C, YHL037C, YHL038C, YHR082C, YHR083W, YHR134W, YHR160C, YHR171W, YHR180W, YHR205W, YIL062C, YIL072W, YIL075C, YIL099W, YIL108W, YIL165C, YIL170W, YIR009W, YIR018W, YIR031C, YIR032C, YJL032W, YJL049W, YJL128C, YJL165C, YJR044C, YJR052W, YJR090C, YJR091C, YJR103W, YJR104C, YJR153W, YKL059C, YKL079W, YKL090W, YKL094W, YKL192C, YKL209C, YKR052C, YKR102W, YKR106W, YLL054C, YLR025W, YLR097C, YLR200W, YLR226W, YLR248W, YLR266C, YLR392C, YLR427W, YML013W, YML029W, YML041C, YML051W, YML078W, YML079W, YML088W, YML099C, YMR056C, YMR068W, YMR091C, YMR110C, YMR160W, YMR186W, YMR255W, YNL005C, YNL026W, YNL039W, YNL063W, YNL064C, YNL077W, YNL083W, YNL147W, YNL176C, YNL194C, YNL253W, YNL257C, YNL261W, YNL264C, YNL276C, YNR006W, YNR034W, YNR047W, YNR051C, YNR071C, YOL065C, YOL067C, YOR005C, YOR008C, YOR022C, YOR023C, YOR058C, YOR069W, YOR087W, YOR138C, YOR229W, YOR256C, YOR267C, YPL005W, YPL020C, YPL022W, YPL105C, YPL147W, YPL150W, YPL152W, YPL164C, YPL168W, YPL180W, YPL188W, YPL194W, YPR025C, YPR047W, YPR049C, YPR066W, YPR081C, YPR134W, YPR140W, YPR148C, YPR155C, YPR172W, YPR185W, YAL018C, YAR064W, YBR012C, YBR076W, YBR287W, YDR043C, YDR250C, YDR373W, YFR014C, YGL191W, YGR180C, YHR136C, YJL026W, YJL037W, YLR038C, YNL058C, YOR031W, YGR087C, YIL166C, YHR008C, YIL129C, YGL256W, YJR030C, YMR077C, YBR264C, YPL177C, YKR040C, YGL056C, YDR128W, YGR139W, YBL101W-A, YOR253W, YOL026C, YDR278C, YHR095W, YCL042W, YNL200C, YPL221W, YLR415C, YMR058W, YPR037C, YER072W, YML028W, YOR325W, YAL039C, YMR112C, YJR107W, YGL088W, YJR058C, YNL142W, YDR090C, YMR071C, YBL093C, YGR293C, YML055W, YDL017W, YDL210W, YGL055W, YCL025C, YDR080W, YDL181W, YNR030W, YJL017W, YIL127C, YDR281C, YDR366C, YFR026C, YJL212C, YPL215W, YEL019C, YBR132C, YHL018W, YNL196C, YPL038W, YAR047C, YPL262W, YHL006C, YPL225W, YBR124W, YOR148C, YKR053C, YBL044W, YER029C, YLR360W, YCL056C, YCR007C, YGR239C, YNL256W, YPR146C, YLR377C, YKL097C, YBR066C, YLR338W, YDL229W, YBR253W, YJR027W, YKL198C, YBL030C, YBR031W, YBR118W, YBR162C, YBR221C, YCR024C-A, YCR106W, YDL046W, YDR012W, YDR133C, YDR134C, YDR276C, YDR342C, YDR343C, YEL027W, YEL034W, YGR038W, YGR243W, YGR279C, YHR094C, YHR105W, YHR175W, YHR181W, YIL056W, YIL162W, YJL059W, YJL097W, YJL158C, YJR105W, YKL051W, YKL056C, YKL097W-A, YKL100C, YKL141W, YKR066C, YLR134W, YLR258W, YLR339C, YML058W, YMR083W, YMR203W, YNL209W, YNL307C, YOL030W, YOR178C, YPL028W, YPR028W, YPR113W, YPR149W, YPR150W, YPR183W, YAL016W, YBL099W, YBL100C, YBR011C, YBR096W, YBR100W, YBR127C, YBR283C, YBR286W, YCL008C, YCL058C, YCR030C, YCR034W, YCR069W, YDL015C, YDL023C, YDL061C, YDL086W, YDR038C, YDR039C, YDR050C, YDR151C, YDR178W, YDR233C, YDR284C, YDR298C, YDR345C, YDR359C, YDR382W, YDR385W, YDR400W, YDR407C, YDR538W, YEL024W, YEL033W, YEL063C, YER057C, YER081W, YER120W, YFL011W, YGL012W, YGL206C, YGR022C, YGR026W, YGR082W, YGR107W, YGR172C, YGR191W, YGR204W, YGR260W, YHL005C, YHL046C, YHR025W, YHR026W, YHR123W, YHR126C, YHR143W, YIL011W, YIL015W, YIL018W, YIL157C, YIR041W, YJL016W, YJL121C, YJL133W, YJL138C, YJL191W, YJR018W, YJR047C, YJR077C, YJR119C, YJR121W, YJR123W, YJR143C, YJR145C, YKL060C, YKL147C, YKL148C, YKL157W, YKL164C, YKL169C, YKR033C, YLL041C, YLL064C, YLR041W, YLR044C, YLR056W, YLR058C, YLR081W, YLR089C, YLR110C, YLR177W, YLR264W, YLR284C, YLR304C, YLR340W, YLR354C, YLR372W, YLR388W, YML022W, YMR007W, YMR011W, YMR015C, YMR092C, YMR101C, YMR156C, YMR205C, YMR215W, YMR261C, YMR323W, YNL069C, YNL135C, YNL195C, YNR076W, YOL039W, YOL073C, YOL086C, YOL120C, YOL156W, YOL161C, YOR002W, YOR009W, YOR010C, YOR085W, YOR108W, YOR128C, YOR129C, YOR142W, YOR161C, YOR176W, YOR230W, YOR298W, YPL004C, YPL036W, YPL048W, YPL057C, YPL059W, YPL061W, YPL135W, YPL179W, YPL218W, YPL220W, YPL246C, YPL272C, YPR063C, YPR080W, YPR181C, YBR290W, YCR010C, YCR091W, YDL107W, YDL129W, YDR066C, YDR529C, YFL026W, YGL018C, YGL059W, YNL144C, YOR003W, YAL037W, YAR023C, YBR003W, YBR020W, YBR044C, YBR091C, YBR185C, YBR282W, YCR015C, YCR038C, YCR043C, YDL119C, YDL146W, YDL220C, YDR057W, YDR123C, YDR125C, YDR222W, YDR225W, YDR277C, YDR286C, YDR347W, YDR408C, YDR438W, YDR479C, YDR483W, YEL039C, YEL057C, YEL073C, YER066W, YER076C, YER084W, YER121W, YER189W, YFL017C, YFL046W, YFR006W, YFR008W, YGL115W, YGL208W, YGL214W, YGL218W, YGR021W, YGR023W, YGR024C, YGR064W, YGR076C, YGR096W, YGR108W, YGR174C, YGR182C, YGR236C, YGR288W, YHL042W, YHR195W, YHR210C, YIL006W, YIL012W, YIL028W, YIL050W, YIL057C, YIL089W, YIL102C, YIL113W, YIL122W, YJL100W, YJL169W, YJL199C, YJR039W, YJR050W, YJR101W, YKL003C, YKL016C, YKL061W, YKL093W, YKL121W, YKL160W, YKL170W, YKL194C, YKR034W, YKR067W, YLR006C, YLR016C, YLR030W, YLR036C, YLR112W, YLR125W, YLR128W, YLR204W, YLR211C, YLR233C, YLR257W, YLR288C, YLR326W, YLR334C, YLR395C, YLR408C, YLR414C, YLR444C, YML050W, YML107C, YML120C, YMR031C, YMR053C, YMR073C, YMR162C, YMR204C, YMR206W, YMR284W, YNL010W, YNL025C, YNL127W, YNL139C, YNL217W, YOL116W, YOL118C, YOR053W, YOR100C, YOR103C, YOR122C, YOR150W, YOR187W, YOR251C, YOR312C, YOR327C, YOR348C, YOR352W, YOR388C, YOR394W, YPL001W, YPL033C, YPL066W, YPL148C, YPL230W, YPL275W, YPL276W, YPR005C, YPR014C, YPR192W, YPR194C, YBR005W, YER025W, YFL027C, YGL080W, YGL205W, YHL028W, YHR185C, YIL076W, YJL166W, YLR046C, YMR035W, YMR238W, YMR252C, YNL192W, YNL202W, YOL108C, YOR385W, YPR165W, YAR033W, YBL038W, YBR009C, YBR010W, YBR151W, YCL067C, YCR096C, YDL137W, YDL192W, YDR073W, YDR086C, YDR224C, YDR377W, YDR378C, YER015W, YGL187C, YHR162W, YJL167W, YJL216C, YKR009C, YLR165C, YMR197C, YNL157W, YOL002C, YOL109W, YOR180C, YPL010W, YPL233W, YBR036C, YDR297W, YGR149W, YGR224W, YNL043C, YPL067C, YPL170W, YCR046C, YDR387C, YFL050C, YGL051W, YHR132C, YIL112W, YJL141C, YKR098C, YLR052W, YLR206W, YML129C, YNL203C, YNR014W, YOL043C, YOL096C, YPR184W, YAL028W, YAL055W, YAR062W, YBL095W, YBL102W, YBR122C, YBR157C, YBR161W, YBR251W, YBR298C, YCR039C, YCR083W, YDL018C, YDL067C, YDL078C, YDL091C, YDL215C, YDL216C, YDR022C, YDR067C, YDR079W, YDR181C, YDR186C, YDR196C, YDR262W, YDR306C, YDR319C, YER188W, YGL004C, YGL035C, YGR036C, YGR062C, YGR120C, YGR131W, YGR141W, YGR167W, YGR287C, YHL024W, YHR080C, YHR097C, YIL077C, YJL046W, YJL070C, YJL096W, YJL113W, YJL146W, YJL180C, YJR019C, YJR049C, YKR058W, YLL005C, YLR078C, YLR151C, YLR271W, YLR295C, YLR351C, YLR375W, YMR023C, YMR025W, YMR135C, YMR210W, YMR267W, YMR278W, YMR293C, YNL073W, YNR037C, YNR040W, YNR072W, YOR028C, YOR316C, YOR328W, YOR363C, YPL039W, YPL040C, YPL099C, YPL107W, YPL134C, YPL138C, and YPL140C.


[0008] The base sequences of those yeast genes and the amino acid sequences of the corresponding protein are disclosed in public databases such as MIPS in Germany: Munich Information Center for Protein Sequence, and SGD in USA: Saccharomyces Genome Database, and are known via the internet.


[0009] In addition to the yeast genes as described above, genes that are homologous to the yeast genes and are derived from other species may be used in the invention. In this context, “a gene(s) that is (are) homologous to the yeast genes” means genes that comprise a base sequence having a homology of 50% or more, preferably 80% or more to the base sequences of yeast genes, and that encode a protein having the same functions as the proteins encoded by the yeast genes.


[0010] Cells as used herein may be either eukaryotic or prokaryotic cells as long as they comprise the genes as described above. Preferred cells are yeast cells.


[0011] Methods for detecting mRNA have been previously known, and any one of those methods may be used in the present invention.


[0012] As an embodiment of the invention, mRNA is detected through reverse transcription-PCR. Reverse transcription-PCR is well known in the art. See, for example, NAKABEPPU Yusaku, et al.: Cell Technology, suppl. Tips series, Modified PCR Tips, Shujunsha Co.Ltd., 1999, pp25-43. For example, the invention comprises:


[0013] (1) adding a test material to the cell, and incubating the mixture;


[0014] (2) extracting mRNA from the cell;


[0015] (3) preparing cDNA from the mRNA via reverse transcription using labeled nucleotides; and


[0016] (4) hybridizing the cDNA as used as probe with the gene as described above.


[0017] Incubation of cells may be conducted using usual media and usual temperatures. Test materials comprising a chemical substance to be tested are added to the medium, and the cells are incubated further for several hours. Concentrations of the test materials are selected to not lead to cell death. Test materials may comprise one or more chemical substances.


[0018] For methods of extraction of mRNA, it is well known that a polynucleotide having a poly T structure which is immobilized on the surface of magnetic beads or latex beads is used to trap the mRNA, and then the mRNA is washed and eluted with spine column in view of the fact that a poly A chain is attached to the 3′ terminus of mRNA, which is readily conducted using a commercially available kit such as Oligotex-dT30<Super>mRNA Purification Kit, Takara. The mRNA is reverse-transcribed with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides. As such, labeled cDNAs that are introduced with fluorescence-labeled nucleotides during the reverse transcription are obtained. Reverse transcriptases and nucleotides that are labeled with Cy3-dUTP or Cy5-dUTP are also commercially available (for example, Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL). Fluorescence-labeled cDNAs are detected with a fluorophotometer.


[0019] RT-PCR is a procedure for detection and quantitative determination of an intended RNA in a form of the amplified cDNA, which comprises reverse-transcribing mRNA into cDNA with a reverse transcriptase, and conducting PCR using the cDNA as a starting material as well as specific primer sets and a thermostable DNA polymerase.


[0020] In the present step, a microarray containing the gene as described above (DNA tip) may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections, which is a preferred embodiment of the present invention.


[0021] As another embodiment of the invention, the mRNA is detected by northern blotting. Northern blotting is well-known in the art (OGATA Nobukuni, NOJIMA Hiroshi: Genetic Engineering Keywords Book, revised 2nd ed., Yodosha, cojp, 2000, pp299-301). For example, the process comprises


[0022] (1) adding a test material to the cell, and incubating the mixture;


[0023] (2) extracting mRNA from the cell; and


[0024] (3) hybridizing the mRNA with the gene as described above.


[0025] Procedures of northern blotting comprises electrophoresing the RNA, transferring the pattern to a filter, and hybridizing it with a specific probe labeled with an isotope, thereby analyzing the presences and the amount of the mRNA in a sample as well as the length of the same.


[0026] In the present step, a microarray containing the gene as described above (DNA tip) may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections.


[0027] In further another embodiment of the present invention, the detection of mRNA is conducted by detecting the production of a polypeptide encoded by the yeast gene as described above. The production of a polypeptide may be detected for example using an antibody directed to the polypeptide.


[0028] Toxic substances to be detected according to the present invention include arsenic, cadmium, mercury, 4-nitroquinolin-N-oxide, 2,4,5-trichlorophenol, y-hexachlorocyclohexane, manganese ethylenebis(dithiocarbamate), 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile, tetramethylthiuram disulfide, Zinc N,N′-ethylenebis(dithiocarbamate), gingerol, acrolein, and dimethylsulfoxide, all of which are mutagenic.


[0029] The following examples are presented for purpose of further illustration of the invention, and such examples are not intended to be limiting the invention in any respect.







EXAMPLES


Example 1

[0030] Yeast (Saccharomyces cereuisiae S288C (α SUC2mal mel gap2 CUP1)) were incubated at 25° C. on YPD medium (yeast extract 1%, polypepton 2%, glucose 2%). One of toxic chemical substances was added to the cells at logarithmic growth phase, and the cells were further incubated for two hours. Cells were cultured without any chemical substance in the same condition, and were used as control. Concentrations of the chemical substances were defined to inhibit the growth of the yeast but not lead to death.
1Chemical SubstancesConcentrations (1) Na2As0.3mM (2) CdCl20.3mM (3) HgCl20.7mM (4) PbCl22mM (5) 4-nitroquinolin-N-oxide0.2μM (6) 2,4,5-trichlorophenol16μM (7) γ-hexachlorocyclohexane1.3mM (8) manganese ethylenebis(dithiocarbamate)2ppm (9) 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile10μM(10) Tetramethylthiuram disulfide75μM(11) zinc N,N′-ethylenebis(dithiocarbamate)2ppm(12) 8-methyl-N-vanillyl-6-nonenamide0.82mM(13) gingerol1.36mM(14) acrolein0.20mM(15) dimethylsulfoxide1.41M(16) Roundup (trademark, herbicide) 1)1500-fold dilution(17) sodium dodecylbenzosulfonate0.02%(18) sodium lauryl sulfate0.01%1) N-(phosphomethyl) glycinate ammonium 41.0%, surfactant 59.0%


[0031] After completion of the incubation, the culture was centrifuged to collect the cells. To the cells, sodium acetate buffer (50 mM sodium acetate, 10 mM EDTA, 1% SDS) was added, and the mixture was shaken at 65° C. for five minutes, followed by returning to room temperature, and obtaining the supernatant, of which the procedures were repeated two times. To the supernatant, ½ amount of a solution of phenol/chloroform was added, and the mixture was centrifuged to give a supernatant, which was added with an equal amount of chloroform, and the mixture was centrifuged to give a supernatant. To the supernatant, an equal amount of isopropanol containing 0.3 M sodium acetate was added, and the mixture was allowed to stand at room temperature for 30 minutes, after which the mixture was centrifuged to give a sediment of the whole RNAs. Seventy % ethanol was added to the sediment, and the mixture was again centrifuged to give a sediment, which was then dried and dissolved in water. mRNA was isolated from the whole RNAs as followings. In view of the fact that a poly A chain is attached to the 3′ terminus of mRNA, a polynucleotide having a poly T structure which was immobilized on the surface of latex beads was used to trap the mRNA, and then the mRNA was washed and eluted with spine column (Oligotex-dT30<Super>mRNA Purification Kit, Takara). Reverse transcription of the mRNA was conducted with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides to give cDNAs that were introduced with Cy3-dUTP or Cy5-dUTP during the reverse transcription.


[0032] The labeled cDNAs were dissolved in TE buffer (10 mM Tris-HCl/1 mM EDTA, pH8.0), and the solution was dropped on the DNA chip containing the whole genes of yeast (DNA Chip Research Inc. Japan) so that the cDNAs were hybridized on the DNA chip at 65° C. for over 12 hours. The fluoresces intensity of the DNA chip was read with a scanner, and the ratio relative to the fluorescence intensity resulting from the absence of chemical substance was estimated as the following, which is shown in Tables 1 to 9:
1ThelevelofexpressedmRNAinthepresenceofchemicalsubstanceThelevelofexpressedmRNAintheabsenceofchemicalsubstance2TABLE 1Unknown protein yeast genesyeastThe level of expressed mRNA in the presence of chemical substance/genes(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)YCR102C3.43.22.41.10.70.41.14.99.861.5YDL218W3.51.22.61.40.70.91.11.572.512.6YDR533C3.44.93.51.81.32.21.75.47.312.7YGR110W1.63.12.25.90.90.91.71.56.44.8YKL071W8.33.85.42.81.118.63.724.7162.2109.2YLR460C2.12.12.01.11.30.61.18.113.931.6YMR090W6.99.52.33.50.73.82.73.916.76.1YOL150C4.13.79.90.91.05.22.43.710.88.3YBL048W2.07.92.32.81.32.01.91.27.24.4YBL107C1.41.10.41.51.21.12.11.91.03.1YFL024C1.01.11.10.71.12.03.30.90.50.5YGL121C2.65.01.44.20.99.84.73.07.015.0YHR029C2.81.81.81.81.02.72.02.713.68.6YHR209W2.81.10.84.51.83.25.02.02.96.4YKL107W2.42.50.50.81.12.01.10.928.28.3YKR075C1.50.72.74.51.21.51.42.00.20.6YLL056C2.12.33.02.01.10.61.01.358.88.8YLR297W2.42.13.51.71.30.81.11.32.15.5YOR338W1.81.80.51.71.62.61.32.20.63.5YOR391C2.12.00.91.21.31.62.02.818.818.1YPL280W1.71.91.92.01.41.91.82.349.814.0YLR346C4.42.02.14.51.45.55.61.38.66.6YOR049C2.50.912.81.41.38.44.20.91.11.9YAL034C1.11.82.81.11.01.51.81.03.03.3YDR476C0.71.86.01.20.53.11.51.31.73.4YGR035C1.60.61.20.61.33.31.10.91.10.5YGR284C1.02.04.01.41.21.42.21.14.31.8YHR054C1.70.92.21.01.02.91.61.82.67.7YLR008C0.90.50.70.91.32.72.01.00.40.7YMR315W4.31.81.74.22.92.02.42.6YNL211C1.21.00.81.01.07.43.11.10.81.1YOL031C0.91.91.01.71.21.02.52.12.31.4YOL101C0.90.80.41.71.60.50.70.90.10.3YAR031W1.51.11.11.71.12.91.61.22.71.6YBL049W2.911.82.12.91.11.71.95.25.2YBR062C1.31.70.41.21.41.91.51.95.42.2YCR013C1.31.45.01.11.11.81.60.70.81.3YDL027C1.22.01.71.71.22.12.91.52.02.3YDL110C1.51.41.12.10.81.72.51.83.02.3YDL169C1.71.71.11.31.12.62.11.37.34.7YDR070C2.26.43.63.50.96.21.41.913.96.0YDR210W1.11.00.91.02.01.21.51.40.51.0YDR214W1.34.04.51.31.11.71.51.55.52.4YDR435C1.21.11.21.41.22.52.11.20.82.1YER037W2.02.10.81.11.33.22.61.01.05.5YFL044C1.01.50.82.31.61.31.61.45.23.7YFR003C1.21.50.81.61.02.21.41.48.33.1YFR020W1.00.91.21.00.91.41.10.93.73.5YFR044C0.91.33.81.10.92.11.20.82.12.2YGR010W1.21.60.91.20.81.21.71.613.68.9YGR142W2.76.215.31.31.30.91.41.536.812.2YGR161C2.02.25.43.81.01.41.41.32.03.8YGR212W1.51.71.51.31.21.01.13.8YGR268C1.12.32.02.51.11.11.01.14.11.6YHR016C0.81.51.71.51.83.70.82.82.0YHR087W1.22.78.62.80.74.23.41.24.13.9YJL048C1.72.52.02.90.91.50.71.51.23.8YJL144W1.91.62.21.61.21.71.71.314.68.9YJL163C1.21.91.71.50.92.82.30.714.52.5YJR074W1.01.42.02.00.71.21.81.33.73.1YKL065C1.92.01.31.71.02.33.81.83.13.9YKR011C1.11.60.91.61.22.32.72.04.74.4YKR018C0.71.11.70.70.91.71.00.73.91.7YKR046C1.97.82.81.80.61.91.30.83.92.0YKR049C1.64.21.03.20.93.02.41.32.23.2YLR132C1.01.10.31.11.21.11.10.74.52.5YLR161W0.90.80.80.70.91.21.30.81.01.5YLR217W0.92.02.10.71.41.41.51.03.28.2YLR328W1.31.21.30.90.94.85.41.10.91.2YML128C1.53.34.14.10.55.12.81.15.13.1YMR040W3.12.90.92.81.72.85.11.71.41.4YMR251W1.31.31.80.62.21.63.11.73.111.6YMR322C2.04.31.52.91.41.81.72.121.310.3YNL094W0.91.41.11.01.42.91.22.03.52.6YNL134C2.36.04.50.91.71.41.53.26.15.9YNL155W1.11.21.10.91.43.01.31.75.82.7YOR059C1.21.20.40.91.41.12.21.37.64.6YOR152C4.52.53.42.90.84.53.21.210.05.0YOR173W0.72.36.32.00.93.54.91.45.23.7YOR289W1.61.51.02.01.24.26.12.42.41.7YPR030W1.71.41.41.01.21.31.20.92.52.4YAL008W1.42.42.02.40.71.61.91.31.81.5YBR053C1.01.62.42.41.62.74.11.22.92.1YBR099C1.01.47.21.81.00.50.91.53.412.9YBR137W1.12.21.43.50.92.42.72.02.21.8YBR203W1.41.41.62.40.90.60.91.31.11.8YCL049C1.91.31.41.21.62.32.11.02.01.9YCR082W1.41.20.71.21.31.31.51.54.32.3YDL054C1.32.22.71.11.21.20.90.73.52.1YDL115C1.41.00.51.80.81.51.81.66.63.6YDL144C0.80.91.21.51.01.81.00.93.61.2YDL223C0.71.15.02.50.90.81.00.33.81.5YDR032C1.72.23.52.51.42.72.82.43.12.9YDR330W0.81.51.20.81.22.31.31.13.92.6YDR411C0.92.81.81.21.60.82.00.90.71.0YDR511W1.31.70.92.31.02.01.51.72.52.2YDR545W0.61.20.60.71.41.01.20.61.80.7YER004W1.01.51.91.41.51.21.41.14.52.9YER035W1.41.61.61.91.50.91.91.21.21.4YER079W1.11.61.92.00.81.51.91.45.33.4YER158C1.20.90.93.10.80.71.20.92.11.6YER163C1.12.41.21.60.82.01.51.45.43.4YER175C0.91.21.32.20.90.82.31.11.911.5YFL006W0.82.81.61.01.41.21.01.03.21.7YFL010C1.04.81.31.01.31.91.51.03.11.4YFL032W0.41.51.60.80.90.61.10.40.50.6YGL037C1.52.76.52.10.91.32.91.22.11.6YGL047W1.01.91.62.31.31.51.71.14.55.7YGL053W1.51.51.22.52.02.73.71.23.32.4YGL199C1.11.71.71.00.70.71.30.70.1YGR101W1.01.31.21.11.20.91.50.84.01.4YGR130C0.90.70.61.61.40.91.30.92.01.5YGR154C1.82.92.20.51.21.42.01.725.29.1YGR221C0.92.20.91.40.93.01.21.10.7YHR138C2.81.82.22.81.53.83.01.45.34.6YHR199C1.92.03.22.01.21.11.11.08.66.0YIL041W1.01.22.11.30.51.00.80.91.81.4YIL087C1.31.93.41.61.44.11.81.12.41.8YJL057C1.51.21.61.71.51.42.71.57.36.1YJL066C0.91.21.22.50.81.41.60.82.02.1YJL082W1.40.82.41.11.70.20.40.91.42.9YJL151C1.02.43.21.21.32.21.40.80.51.6YJL152W0.91.51.81.31.61.51.20.70.31.0YJL161W1.72.21.54.61.18.03.61.43.12.1YJL171C2.30.72.81.41.02.71.40.91.01.7YJR008W1.61.51.21.71.42.22.91.11.81.9YKL151C1.23.11.72.51.02.05.61.03.33.5YKL153W1.11.42.00.71.02.91.10.70.81.4YKL195W0.80.50.41.11.92.52.11.23.62.1YLR054C2.01.50.42.41.31.21.11.12.71.1YLR149C1.41.93.42.30.81.41.61.16.25.2YLR152C0.71.31.10.91.12.11.41.20.61.1YLR324W0.71.20.91.01.31.21.01.03.11.4YLR350W1.21.93.22.3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level of expressed mRNA in the absence of chemical 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.91.01.00.71.10.90.90.28YKL169C0.71.01.30.82.60.91.10.45YKR033C0.30.40.90.91.10.61.00.90.28YLL064C1.01.11.31.11.21.61.21.00.68YLR041W1.10.40.30.51.30.50.70.90.69YLR177W0.91.11.51.00.51.31.11.51.25YMR007W0.90.81.31.21.81.12.51.00.30YMR156C1.10.71.01.20.71.31.21.10.40YMR215W1.10.40.20.50.70.20.70.71.59YNL195C2.90.61.61.51.46.40.80.90.32YOL073C1.70.81.60.81.61.71.21.20.54YOR129C1.10.60.20.50.60.30.60.45.22YOR161C4.60.50.70.91.42.00.71.20.82YPL004C1.70.91.31.01.12.01.22.24.52YPL246C1.10.80.90.71.21.11.20.90.98YPL272C1.10.71.11.10.62.50.91.20.25YPR063C1.00.70.81.01.01.21.00.91.41YDL129W0.60.90.50.80.51.40.60.80.69YDR066C0.60.81.41.30.91.41.11.10.57YGL059W1.41.02.01.21.61.71.41.40.49YNL144C1.71.41.01.10.11.72.42.80.51YAL037W0.50.81.11.20.80.60.90.90.55YAR023C1.01.21.11.03.11.60.91.10.62YCR015C1.10.90.61.20.91.11.11.20.58YCR043C1.00.60.81.61.20.81.01.11.25YDL146W1.41.01.41.01.71.81.01.20.62YDR057W1.00.70.91.21.11.70.71.10.70YDR222W1.00.50.81.30.50.60.70.80.52YDR286C1.10.91.41.30.82.11.11.40.90YDR438W1.10.81.21.31.01.21.61.20.48YDR479C1.01.01.21.41.62.11.11.50.51YEL057C0.70.81.51.51.01.80.91.00.44YEL073C1.10.51.01.12.81.01.30.80.38YER084W0.80.70.92.61.50.80.90.30YER121W1.20.70.61.30.94.61.21.80.73YER189W0.70.80.70.90.90.80.80.80.43YFL017C1.11.00.71.10.61.81.51.81.21YFL046W1.30.80.71.31.01.11.41.60.68YFR008W0.70.90.81.10.81.51.01.01.26YGL214W0.40.80.61.10.90.81.00.80.61YGL218W0.10.81.30.91.10.71.01.00.53YGR021W0.60.90.91.20.82.11.01.00.58YGR024C1.00.70.51.41.01.20.81.31.61YGR064W1.70.80.92.11.01.30.80.90.50YGR182C0.90.70.72.20.42.01.01.71.95YGR236C1.00.91.21.20.77.91.51.90.30YHL042W0.70.61.31.21.11.91.10.90.37YIL012W0.90.60.41.11.10.91.00.90.28YIL028W1.10.51.01.10.91.11.31.00.27YIL057C0.80.60.91.50.811.11.13.60.26YIL089W0.70.60.71.40.61.31.41.30.31YIL102C0.60.71.00.80.61.21.00.18YIL113W2.50.81.31.20.91.61.41.30.48YIL122W2.11.00.71.01.61.40.90.90.35YJL100W1.50.91.41.21.21.41.51.10.38YJL169W0.40.50.71.00.90.61.10.90.35YJL199C1.00.80.91.90.93.71.01.00.59YJR039W1.80.71.50.61.21.51.31.30.24YJR101W1.20.50.50.90.51.21.01.12.04YKL061W1.10.70.81.20.61.51.31.60.92YKL121W1.60.81.01.20.81.61.61.10.31YKL160W1.40.91.61.50.81.61.52.22.19YLR016C1.00.70.80.90.71.31.01.31.15YLR030W0.20.81.51.20.62.11.01.00.29YLR036C0.80.70.71.30.61.41.01.41.07YLR112W0.50.50.70.80.40.41.00.80.39YLR125W1.10.50.81.30.71.61.21.20.29YLR128W1.40.71.21.40.91.51.21.20.25YLR204W1.60.81.11.81.02.51.21.31.26YLR211C0.80.71.11.23.61.91.31.30.35YLR257W1.21.01.00.91.01.71.82.65.20YLR326W6.60.50.41.10.70.90.81.00.33YLR334C0.80.80.92.22.50.70.81.00.30YLR408C0.70.81.12.10.91.11.21.20.79YLR414C1.20.61.01.02.10.93.93.62.21YLR444C1.10.60.51.11.30.70.90.90.50YML050W1.20.80.91.91.01.50.81.10.42YML107C0.90.70.61.31.01.31.21.50.67YMR031C0.80.71.01.00.71.60.91.31.26YMR204C0.70.71.11.21.51.10.91.10.31YMR206W1.81.01.21.40.32.21.01.20.17YNL010W1.10.90.71.20.91.21.01.74.53YNL127W1.01.01.71.01.51.40.91.40.36YNL217W0.71.01.00.90.51.01.32.12.35YOL118C1.40.61.73.01.00.50.91.00.24YOR053W1.30.60.91.21.01.31.21.20.77YOR352W1.11.01.21.30.72.51.31.70.59YOR394W1.90.91.30.90.91.71.61.10.51YPL033C0.70.60.71.10.80.40.90.80.23YPL066W1.01.10.90.70.71.21.31.30.77YPR014C0.50.70.71.00.90.80.91.10.29YBR005W0.81.71.90.91.11.72.94.61.00YFL027C1.30.61.10.31.41.25.15.21.74YGL080W0.81.00.71.60.91.71.32.91.70YMR252C1.40.81.11.11.12.11.52.20.86YOR385W1.20.62.80.80.81.24.65.91.17YAR033W1.50.91.51.30.92.01.13.01.15YBR151W0.90.91.10.81.03.01.42.41.83YHR162W1.31.21.52.01.11.41.32.73.64YLR165C1.40.91.21.40.51.61.12.10.78YNL157W1.30.91.61.51.01.01.92.31.41YOL002C0.81.10.20.50.61.71.52.15.33YPL233W0.90.61.01.00.41.01.91.90.48YGR149W1.81.22.61.02.41.32.01.70.71YNL043C0.70.92.11.21.60.82.71.60.68YPL067C0.91.40.90.71.51.12.91.70.40YPL170W1.10.91.11.41.21.62.21.41.05YGL051W1.41.01.51.20.82.61.41.91.06YIL112W1.41.21.11.31.82.41.21.30.45YLR052W1.11.00.81.21.02.40.70.90.77YNL203C1.10.91.22.71.25.61.31.70.21YNR014W4.40.91.54.91.02.41.11.00.31YAL028W1.01.01.51.62.21.71.01.00.30YBL095W1.20.81.01.00.42.21.31.90.72YBR157C0.60.60.50.90.21.91.30.80.69YDL091C1.51.01.31.51.92.41.11.60.47YDL216C0.70.91.21.11.01.81.01.60.42YDR067C0.90.91.21.51.52.41.31.40.76YDR186C0.71.11.10.80.82.31.10.90.50YDR196C1.30.71.21.00.72.71.21.91.54YDR262W1.60.80.91.71.53.81.01.41.11YDR306C2.10.91.21.11.22.41.01.50.77YDR319C1.31.01.30.82.02.12.21.23YER188W1.20.91.11.10.32.51.01.10.61YGL004C1.00.81.30.90.62.21.11.40.48YGR141W0.60.61.00.72.62.11.11.30.65YHR080C0.71.22.00.90.92.31.11.30.49YHR097C0.70.81.30.92.72.01.71.40.24YIL077C1.31.61.31.30.92.41.31.10.75YJL046W4.20.91.31.31.02.51.01.30.68YLL005C0.90.81.11.71.02.11.11.20.44YLR151C1.10.50.71.30.72.41.01.40.30YLR271W1.30.81.21.21.03.01.51.80.78YMR025W1.20.91.21.81.12.41.01.50.42YMR135C1.11.01.31.01.42.31.51.31.06YMR210W0.80.91.01.01.02.20.81.50.56YNR040W1.20.60.81.50.72.11.11.00.30YPL039W0.90.91.11.10.62.41.11.10.52YPL099C0.80.91.11.30.52.11.01.70.92YPL107W1.10.70.81.70.71.81.01.10.59YPL138C0.50.90.61.32.72.60.81.10.38


[0033]

3





TABLE 2








Mitochondria-located protein genes
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YJR048W
1.3
0.9
2.2
1.4
0.8
0.5
0.3
0.9
0.5
1.5


YOR226C
1.3
2.2
1.7
1.1
1.3
1.2
1.2
1.2
1.3
5.9


YDL174C
0.9
1.8
0.9
1.3
0.5
1.7
3.6
0.8
0.5
1.7


YBL022C
0.4
0.8
1.2
0.7
1.2
1.2
1.0
0.4
2.8
1.2


YCL057W
0.6
1.5
2.3
0.5
1.1
1.8
1.4
1.8
4.2
2.1


YDR258C
1.6
2.3
2.8
1.4
1.3
2.4
3.9
1.9
4.9
13.3


YGR028W
1.4
3.5
1.0
1.8
0.9
1.5
2.1
1.4
1.7
2.0


YGR244C
1.0
1.2
1.6
1.6
0.8
2.6
3.9
1.8
1.4
1.1


YKL142W
1.8
2.7
3.1
1.4
0.7
3.4
6.9
2.3
5.8
5.9


YNL055C
1.1
1.8
5.5
2.0
0.9
2.6
1.2
0.7
1.1
1.0


YNL071W
0.9
0.9
1.7
1.5
0.6
1.3
1.4
0.9
1.1
1.2


YOR020C
1.4
2.1
1.7
1.7
1.5
2.3
1.7
1.7
5.8
2.6


YOR037W
1.0
1.5
0.6
1.4
1.5
1.6
2.5
1.5
1.3
1.0


YDL198C
1.4
1.0
2.1
1.4
0.7
0.8
1.0
1.1
1.9
2.7


YDR231C
1.1
1.6
1.0
1.5
1.1
2.2
1.7
1.3
1.5
1.4


YER178W
0.8
0.9
3.6
1.0
0.7
2.5
1.6
0.8
1.7
1.3


YFL016C
0.8
1.0
1.6
0.9
1.3
1.3
1.4
0.7
6.4
2.9


YGR008C
2.1
3.0
1.7
3.2
0.9
2.9
3.7
1.9
3.1
2.4


YIL155C
1.0
0.7
1.4
3.7
1.3
1.4
2.2
1.0
2.5
2.9


YJL102W
1.1
0.7
0.4
0.8
1.3
1.6
0.6
0.9
3.1
2.2


YJR045C
0.5
1.9
3.9

0.5
1.2
1.0
0.8
3.2
3.0


YLR259C
0.7
1.0
3.1
1.6
1.1
0.9
1.8
0.8
1.8
2.6


YLR348C
1.1
4.5
1.2
1.2
0.9
1.9
0.9
0.9
2.1
1.3


YML054C
1.5
1.8
1.3
3.4
1.3
1.8
1.2
1.5
4.1
1.8


YMR089C
0.8
1.1
0.9
0.9
0.8
1.2
1.2
1.3
5.6
2.5


YMR152W
0.9
1.1
1.8
0.9
0.8
7.5
0.8
0.8
2.7
1.3


YNL104C
1.1
1.3
3.0
0.9
0.8
0.8
0.6
0.9
1.1
2.0


YOR130C
0.8
1.7
1.4
1.0
1.8
1.6
1.3
0.8
2.0
1.7


YPR024W
0.7
1.0
1.3
1.0
1.3
1.0
1.4
0.7
3.0
1.7


YPR067W
1.6
1.2
1.7
0.9
1.3
1.3
1.5
1.4
3.5
3.4


YBR029C
0.7
0.2
1.8
1.0
1.4
0.8
0.4
0.7
2.0
1.1


YCL009C
0.6
0.9
2.0
0.5
0.7
1.8
1.3
1.1
0.9
1.6


YER026C
0.8
0.6
3.3
1.0
1.2
2.5
1.6
0.8
0.9
1.5


YLR109W
0.8
2.9
6.0
0.9
1.3
2.1
2.6
0.9
2.4
2.7


YMR189W
0.7
0.8
1.9
2.8
0.4
1.9
0.8
0.4
0.7
0.9


YNL169C
0.7
1.4
1.4
1.2
0.7
1.4
0.7
0.8
1.1
1.1


YER069W
1.3
0.8
3.3
1.4
1.5
1.3
1.0
1.5
0.8
10.4


YIL022W
0.8
0.7
1.1
1.6
0.8
1.2
0.7
0.8
1.1
1.3


YBR146W
0.9
0.8
0.7
1.5
1.3
2.6
1.5
1.0
0.9
1.1


YDR019C
1.4
0.5
1.7
4.0
0.9
4.8
1.4
0.7
0.4
0.7


YGR207C
1.5
1.1
1.0
1.1
1.5
2.8
1.7
1.9
2.1
2.6


YMR072W
1.1
1.0
1.4
1.0
1.7
2.4
1.4
1.0
3.0
1.2


YNL037C
1.4
1.8
1.7
1.1
1.7
2.8
2.8
1.0
0.6
3.2


YOR136W
1.0
0.9
3.5
1.0
1.5
3.9
3.2
1.1
0.3
3.4


YPL271W
1.2
3.2
4.1
1.2
1.4
3.3
1.2
0.9
0.6
1.2


YAL044C
1.5
1.1
1.0
3.0
0.8
2.2
1.0
0.8
0.4
0.6


YAL054C
1.2
1.1
1.4
1.6
1.1
2.2
1.1
1.1
8.9
4.1


YBR024W
1.0
1.0
1.1
2.4
1.0
2.2
1.9
1.4
1.3
1.4


YDR405W
0.9
1.1
4.7
1.0
1.1
2.4
1.2
0.9
0.6
1.0


YGL068W
1.0
0.6
1.1
1.4
0.9
2.6
1.5
0.9
0.7
0.8


YGR220C
1.1
0.6
0.9
1.1
1.3
2.1
1.4
1.5
0.8
1.5


YHR037W
0.7
0.9
1.3
1.6
0.9
1.8
1.2
1.0
0.9
2.2


YIL070C
1.2
1.0
0.8
1.4
1.3
2.3
1.6
1.1
0.3
0.6


YIL111W
1.6
1.0
1.8
2.7

2.6
3.2
1.2
1.6
1.1


YKL138C
1.2
0.9
0.6
0.9
1.3
2.3
1.9
1.7
1.1
2.1


YKL150W
1.1
2.0
3.0
1.4
1.4
2.3
2.4
1.3
1.1
1.3


YKR006C
1.0
0.7
1.2
1.2
1.4
2.4
1.6
1.2
1.0
1.5


YLR142W
4.4
2.7
1.1
6.1
1.3
3.1
1.2
2.1
3.1
4.4


YML110C
1.1
0.8
1.9
1.6
0.8
2.6
2.0
1.4
2.7
2.2


YNL284C
1.1
0.7
0.3
1.4
1.8
1.0
2.8
1.6
0.9
1.9


YDR268W
0.8
1.5
0.4
1.2
2.2
1.0
2.4
1.0
1.0
2.0


YMR193W
1.4
1.2
0.5
1.9
2.2
1.7
2.7
1.7
0.8
1.1


YOR374W
1.3
4.5
7.3
3.9
0.9
1.4
1.9
0.9
2.3
5.9


YER061C
0.9
0.9
1.2
2.5
0.8
0.4
0.9
0.7
0.3
0.7


YIL136W
1.1
1.0
1.2
2.5
1.0
1.0
1.8
1.1
3.4
1.7


YLL009C
1.0
1.2
0.6
1.9
1.5
1.2
1.7
1.0
1.3
1.7


YLR163C
1.0
0.9
0.7
1.4
1.6
1.3
1.7
1.4
2.6
2.9


YBR291C
2.0
0.9
1.0
1.5
0.9
1.1
0.9
2.2
0.9
1.0


YIL094C
1.5
0.4
0.8
0.7
1.4
1.2
1.3
3.6
0.3
0.4


YAL015C
1.2
1.1
1.7
1.9
1.1
0.7
1.2
1.1
4.0
2.7


YJR095W
1.2
20.5
1.9
6.7
1.2
1.5
2.0
0.9
0.5
6.3


YKL085W
1.4
2.3
1.6
1.2
1.2
1.9
1.5
1.2
1.9
3.0


YMR177W
1.4
0.8
1.1
1.0
1.6
0.8
1.0
1.2
2.4
3.8


YPL224C
1.0
2.2
1.3
2.5
0.6
1.3
2.2
1.3
3.2
4.2


YER014W
1.0
0.9
0.9
0.6
0.8
4.0

1.2
3.5
1.1


YFR049W
1.5
1.5
1.8
1.2
1.3


1.3
2.6
1.5


YGR112W
1.0
2.9
1.1
1.3
0.9
1.1
1.3
1.3
2.6
1.3


YLL001W
0.9
0.7
1.2
1.2
0.6
1.0
0.8
1.0
3.5
2.4


YML042W
0.9
1.4
1.5
2.2
1.0
0.9
0.8
1.6
3.8
2.4


YNL213C
1.7
11.6
0.9
1.5
1.3
1.2
1.4
1.8
3.0
1.5


YOR386W
1.0
0.8
1.3
1.5
1.2
3.3
1.8
1.0
4.1
3.0


YBR037C
0.8
0.8
1.3
2.4
0.7
1.2
1.2
1.0
3.0
1.9


YCR024C
1.1
1.0
1.5
0.8
0.8
2.9
1.0
1.2
2.5
1.7


YDR194C
0.7
0.9
0.5
1.0
1.0
1.0
1.3
1.4
2.8
2.2


YER017C
0.8
1.1
1.4
1.3
1.0
0.5
1.1
0.5
2.7
1.8


YGL125W
1.0
3.2
4.3
0.7
0.9

1.7
0.8
2.1
2.1


YGR029W
1.1
1.4
1.0
1.0
0.8
0.6
1.6
1.7
2.7
1.1


YHL038C
1.0
1.2
1.4
0.8
1.3
0.8
1.2
1.1
4.0
1.7


YKL192C
1.1
1.0
3.7
1.1
1.1
1.8
1.1
0.9
3.5
1.6


YKR052C
0.9
1.1
2.6
2.6
1.0
0.5
1.9
1.1
1.9
3.6


YML078W
1.2
1.9
2.5
1.5
0.7
1.4
1.3
1.4
2.6
2.2


YMR056C
1.1
1.3
1.7
1.0
1.1
0.9
1.4
1.2
1.8
1.1


YNL005C
1.1
1.0
0.6
1.2
1.2
1.7
1.3
1.5
2.0
2.0


YPR047W
1.0
1.0
0.9
1.5
0.9
1.0
1.8
1.2
2.1
1.9


YPR134W
1.1
1.1
0.8
1.7
1.5
0.6
1.5
1.4
1.8
2.3


YGL191W
1.7
1.6
1.4
1.8
0.9
1.6
1.0
1.6
1.1
1.3


YLR038C
2.3
1.1
0.6
2.1
1.8
1.2
1.0
1.4
0.4
0.9


YHR008C
1.3
5.4
4.8
1.8
0.6
1.0
0.7
0.9
1.7
2.4


YPR037C
1.2
2.3
1.6
1.3
0.8
0.9
1.2
1.1
1.5
1.3


YAL039C
1.1
2.2
1.7
1.0
1.1
0.8
1.0
1.2
1.6
2.2


YDL181W
1.3
1.8
1.9
1.8
1.7
1.2
1.1
0.6
0.7
0.8


YPL215W
1.1
1.9
1.0
1.5
0.8
0.7
0.7
1.1
1.7
1.2


YPL262W
1.0
1.7
3.8
1.2
0.6
1.6
1.3
1.0
1.4
5.8


YNL256W
0.7
1.6
0.6
0.6
1.0
0.5
0.6
0.9
0.8
0.6


YBL030C
1.0
0.9
4.5
0.9
0.7
1.1
0.9
0.8
0.4
0.9


YBR221C
0.8
0.7
3.2
1.5
1.3
1.7
1.5
0.8
1.0
1.3


YKL141W
1.6
1.1
4.7
1.7
1.5
1.2
0.5
0.8
0.8
0.5


YKR066C
0.9
1.4
5.5
0.7
1.0
0.9
0.5
0.7
0.7
2.4


YMR083W
1.4
1.7
2.6
1.1
1.5
1.8
1.7
1.1
0.4
1.1


YMR203W
0.8
0.7
3.0
1.4
0.6
1.1
0.8
0.7
0.7
1.2


YBL099W
0.8
0.9
3.1
1.4
1.0
0.9
0.9
0.8
0.9
0.7


YDR178W
2.0
2.0
3.4
2.2
0.9
2.1
0.6
0.9
0.9
0.8


YDR298C
1.3
1.2
2.6
1.3
1.3
1.2
1.0
1.2
1.0
1.6


YEL024W
1.3
0.9
3.8
1.1
1.3
1.1
0.7
1.0
0.7
0.6


YGR082W
1.0
0.9
2.2
1.0
0.9
1.1
0.9
0.8
0.6
0.9


YJL133W
1.0
1.0
2.0
0.9
0.9
0.5
0.5
0.9
0.6
1.4


YJR077C
1.1
1.1
2.0
1.6
0.9
0.9
0.7
0.8
0.4
0.7


YJR121W
0.9
1.1
3.3
1.0
0.8
1.5
1.0
0.7
0.8
1.3


YKL148C
0.9
0.8
3.7
0.7
0.8
0.5
0.6
0.8
1.7
1.7


YLL041C
1.1
0.5
4.6
1.0
1.6
1.2
0.3
0.8
0.7
0.8


YLR304C
0.7
0.6
5.0
0.7
0.6
1.9
0.6
0.6
0.1
2.2


YOR142W
1.0
1.2
3.4
1.0
1.4
1.6
1.0
0.8
1.1
1.5


YOR176W
0.7
2.6
2.7
0.9
1.0
0.9
0.5
1.0
1.0
0.5


YPL135W
0.9
1.2
2.5
1.2
1.6
1.3
1.2
1.0
0.5
2.8


YDR529C
1.8
1.0
0.9
3.2
1.2
0.8
0.5
1.3
0.5
0.6


YGL018C
1.1
1.0
1.8
3.0
1.1
0.4
1.1
0.8
0.5
1.4


YBR003W
0.9
0.8
1.0
1.9
0.7
1.2
1.1
0.9
1.0
1.3


YBR044C
0.8
1.4
0.7
1.9
1.4
1.0
1.5
1.1
0.8
1.2


YBR091C
1.1
1.0
0.6
3.0
1.1
0.7
1.0
1.5
0.7
1.6


YBR185C
1.2
1.0
1.3
2.0
0.8
1.2
1.2
1.1
0.9
1.6


YBR282W
1.0
1.0
0.5
2.3
1.0
1.4
1.2
1.4
1.0
0.9


YDR347W
1.1
0.8
0.9
3.5
0.8
1.2
1.2
1.2
0.8
1.6


YEL039C
1.1
0.7
1.3
5.1
0.9
1.5
0.6
1.1
1.2
1.2


YGR076C
1.3
1.6
0.6
2.3
0.9
1.2
1.7
1.9
1.2
1.8


YGR174C
1.1
1.6
0.6
2.4
1.0
1.4
1.0
1.6
1.8
0.7


YKL003C
1.1
0.7
0.8
1.8
1.0
1.0
1.4
1.2
1.5
2.2


YKL016C
1.5
1.3
0.7
1.7
1.5
0.8
1.5
1.6
1.3
1.8


YKL170W
1.0
0.8
0.5
1.9
1.3
1.5
1.5
1.2
0.9
1.1


YKL194C
0.9
0.7
0.8
1.6
1.8
1.4
2.1
1.1
1.3
1.4


YLR395C
1.8
1.3
2.2
1.9
0.7
0.4

1.0
1.0
0.9


YML120C
1.1
1.2
1.9
1.9
0.6
0.6
0.8
0.9
1.3
1.5


YOR100C
1.3
1.4
1.6
1.7
1.0
1.2
1.6
1.0
2.0
2.6


YOR150W
1.7
1.2
1.0
1.9
0.8
0.9
1.2
1.1
0.8
1.8


YOR187W
1.0
0.5
1.9
2.0
0.6
1.7
1.5
0.7
0.6
0.8


YJL166W
2.1
1.5
1.6
1.3
1.6
0.7
0.8
1.4
1.3
1.2


YMR035W
1.2
1.7
1.5
1.7
0.8
1.5
2.3
1.4
1.7
1.6


YBL038W
1.0
0.9
0.5
1.8
0.9
0.7
8.0
1.6
1.4
1.5


YDR377W
1.3
1.1
1.3
1.4
1.9
1.3
1.1
1.3
1.0
0.9


YGL187C
1.5
0.8
1.6
1.8
1.3
1.1
0.6
0.7
0.6
0.6


YCR046C
1.0
1.2
1.2
1.6
1.0
0.8
1.2
0.9
1.9
1.4


YML129C
1.1
0.9
0.9
1.2
1.7
1.7
1.8
1.2
1.4
2.2


YOL096C
1.1
1.0
1.2
1.6
1.2
1.3
1.7
1.0
1.3
1.4


YBR122C
0.9
0.9
0.3
1.1
1.5
1.1
2.0
1.3
1.1
1.4


YBR251W
1.0
0.9
1.0
1.2
1.3
2.0
1.4
1.3
0.5
1.1


YCR083W
1.1
2.8
1.5
1.8
1.6
2.4
1.8
1.5
1.8
1.8


YDL067C
1.8
1.0
1.6
1.3
2.0
0.9
0.8
1.1
0.9
0.9


YDR079W
1.3
1.1
0.8
1.1
1.2
1.7
1.3
2.6
0.9
0.8


YGR062C
0.9
1.0
0.7
1.4
0.7
0.9
1.3
0.8
1.0
1.4


YJL096W
1.0
1.0
0.8
1.3
1.9
1.0
1.7
1.3
1.0
1.4


YJL180C
0.9
1.6
1.1
1.3
1.5
1.3
1.6
1.0
1.4
1.4


YLR295C
1.4
1.1
1.1
1.7
2.2
1.1
1.1
1.2
1.4
1.2


YMR023C
1.4
1.3
0.5
1.9
1.7
1.1
1.9
1.4
1.5
2.6


YMR267W
0.8
1.8
0.7
0.9
1.0
1.4
1.2
1.5
0.4
0.8


YNL073W
0.8
1.4
0.9
1.7
0.6
0.5
1.1
1.0
0.9
1.8


YOR316C
0.7
2.5
1.5
1.5
1.0
0.9
1.4
0.8
1.6
2.0


YPL040C
1.1
1.0
0.8
1.7
0.8
1.1
0.8
1.1
0.2
1.2


YPL134C
1.5
1.0
1.6
1.6
1.4
1.2
1.2
1.3
0.6
0.8











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YJR048W
1.0
0.8
0.4
2.5
0.6
1.5
1.2
1.2
1.19


YOR226C
1.5
0.6
0.9
2.7
1.0
0.7
1.0
0.7
0.58


YDL174C
0.9
2.8
5.9
1.1
0.6
5.1
2.2
4.0
0.63


YBL022C
1.1
0.9
2.6
1.0
1.5
1.0
0.9
0.7
0.76


YCL057W
1.6
1.0
3.8
1.0
2.8
1.5
0.9
1.1
0.76


YDR258C
1.7
1.8
5.2
1.5
0.6
1.0
1.3
1.3
0.87


YGR028W
1.1
1.5
2.6
1.2
1.0
2.2
1.5
2.6
0.91


YGR244C
1.8
1.9
2.6
1.2
2.0
2.6
1.9
3.1
1.12


YKL142W
2.0
1.9
3.3
2.3
1.3
3.3
2.4
3.6
1.68


YNL055C
1.9
1.7
2.4
0.9
1.1
2.6
1.2
1.7
4.10


YNL071W
1.6
1.3
2.5
0.8
1.1
1.1
1.0
1.2
1.61


YOR020C
2.5
0.8
3.0
1.6
1.5
1.4
1.4
1.7
1.66


YOR037W
1.2
1.2
2.1
1.0
0.9
1.4
1.2
1.6
0.61


YDL198C
2.5
1.2
2.0
1.7
1.2
1.4
1.5
1.1
1.19


YDR231C
1.3
1.1
2.4
1.5
1.0
3.0
1.2
1.3
0.92


YER178W
2.5
1.3
2.4
0.9
1.8
1.0
1.1
0.9
2.18


YFL016C
1.2
1.0
2.8
0.8
0.8
0.6
1.2
0.9
1.25


YGR008C
2.6
2.0
3.4
1.3
1.5
2.3
1.7
4.2
3.03


YIL155C
1.3
1.4
2.0
1.3
1.4
3.8
1.1
1.4
0.51


YJL102W
0.7
0.8
2.6
1.5
1.5
0.6
1.0
1.1
0.22


YJR045C
1.4
1.0
2.3
0.5
2.3
0.8
0.7
0.9
3.78


YLR259C
3.0
0.7
2.5
0.8
2.1
1.3
0.8
1.0
2.09


YLR348C
1.3
0.9
1.9
1.0
2.4
1.1
1.1
1.0
0.64


YML054C
1.4
1.8
2.8
2.1
1.1
7.8
1.1
1.6
0.25


YMR089C
1.3
0.8
2.3
0.9
1.8
1.1
0.9
1.1
0.69


YMR152W
1.2
1.3
1.9
1.1
0.6
1.0
1.5
0.9
0.71


YNL104C
2.1
1.1
2.1
0.9
2.5
1.5
0.9
0.9
1.69


YOR130C
0.6
0.9
2.1
1.3
1.0
0.8
1.5
1.1
0.51


YPR024W
0.9
0.8
2.5
0.7
1.0
1.6
1.1
0.8
0.84


YPR067W
1.8
1.0
3.0
1.6
1.3
0.8
1.0
1.0
0.66


YBR029C
0.7
1.3
1.7
0.9
3.5
0.9
0.6
0.8
1.56


YCL009C
1.5
1.7
1.6
0.7
6.5
0.9
1.1
0.8
0.68


YER026C
0.9
1.7
1.9
1.1
4.0
1.4
1.7
3.2
4.48


YLR109W
1.5
1.6
3.2
2.3
3.9
1.8
1.1
1.2
3.86


YMR189W
8.2
0.6
0.9
1.6
5.6
0.9
1.0
0.8
0.88


YNL169C
0.8
1.0
1.7
0.9
3.4
0.8
1.1
1.3
1.05


YER069W
1.5
0.8
1.4
1.3
2.4
1.1
1.1
0.9
0.25


YIL022W
1.0
0.9
1.2
0.6
2.9
1.1
0.8
0.7
0.52


YBR146W
1.2
1.0
1.7
1.2
1.0
2.9
1.0
1.2
1.61


YDR019C
1.8
0.7
1.0
1.6
1.8
1.8
1.2
1.6
2.48


YGR207C
1.4
1.1
1.0
2.2
0.6
1.8
1.2
1.8
1.49


YMR072W
1.9
0.8
2.1
1.2
0.8
1.7
0.9
1.9
2.06


YNL037C
1.4
1.3
1.9
1.3
0.9
1.4
0.9
1.3
2.05


YOR136W
1.4
1.2
1.5
0.9
1.2
1.3
0.8
1.3
3.20


YPL271W
1.7
0.8
1.2
1.3
0.8
1.4
1.2
1.3
1.34


YAL044C
1.4
0.6
1.1
1.4
0.7
1.0
1.4
1.8
4.07


YAL054C
1.3
1.0
1.8
1.3
0.9
2.5
1.5
1.4
0.24


YBR024W
1.3
1.1
1.7
1.9
0.8
2.3
1.0
1.2
1.14


YDR405W
1.0
1.2
1.3
1.1
2.5
1.3
1.3
0.9
0.44


YGL068W
1.0
1.1
1.0
0.9
0.6
1.8
1.8
1.0
3.35


YGR220C
1.1
0.9
1.1
1.5
1.1
2.3
0.9
1.1
1.42


YHR037W
1.7
1.1
1.1
1.1
1.1
2.0
1.0
1.4
1.15


YIL070C
1.0
0.8
0.7
1.3
1.0
2.4
0.7
1.1
1.69


YIL111W
2.1
0.9
1.7
1.5
1.1
2.5
1.9
3.9
1.52


YKL138C
1.2
0.8
0.8
1.6
0.6
2.5
1.0
1.3
1.29


YKL150W
1.9
1.2
1.8
1.4
0.9
6.1
1.2
2.7
2.20


YKR006C
1.2
0.8
0.9
1.6
0.9
2.3
0.8
1.1
1.39


YLR142W
3.8
0.8
1.2
2.1
1.6
3.4
1.9
3.2
0.28


YML110C
1.7
1.1
1.8
1.4
1.3
2.3
1.1
1.6
2.01


YNL284C
1.3
0.7
1.0
1.5
0.8
2.4
1.0
1.5
1.26


YDR268W
1.1
0.7
1.0
1.4
1.0
1.6
1.1
1.2
0.47


YMR193W
1.6
0.6
0.9
1.5
0.8
3.7
1.1
1.7
0.93


YOR374W
2.6
1.5
1.7
1.1
2.5
2.5
1.2
2.4
1.24


YER061C
2.2
0.7
0.9
1.0
0.8
1.8
1.2
1.2
0.84


YIL136W
4.8
0.9
1.7
1.7
1.5
4.5
1.3
3.2
0.95


YLL009C
3.5
0.7
0.9
1.4
1.1
2.8
0.9
1.2
1.66


YLR163C
2.2
0.7
1.4
1.3
1.2
1.4
0.9
1.1
0.55


YBR291C
1.1
0.9
1.0
1.7
0.5
1.5
0.9
1.3
1.19


YIL094C
1.8
1.0
0.7
1.0
0.5
0.9
0.9
1.0
2.26


YAL015C
1.4
1.0
1.2
1.6
0.7
2.0
1.1
1.2
0.61


YJR095W
0.6
0.7
0.8
1.3
0.8
0.8
1.3
0.9
0.23


YKL085W
1.8
0.8
1.5
1.0
0.5
1.7
0.9
1.3
2.16


YMR177W
1.4
0.6
0.5
1.2
0.8
0.5
0.9
0.9
0.55


YPL224C
0.8
1.1
1.3
1.4
1.0
2.5
1.3
1.9
0.64


YER014W
0.9
1.1
1.5
1.2
2.3
0.8
1.0
0.9
0.43


YFR049W
1.7
1.2
1.4
1.2
0.7
0.9
1.3
1.0
0.83


YGR112W
1.3
0.7
1.1
1.1
1.2
2.8
0.9
1.2
0.31


YLL001W
0.9
0.7
1.7
1.2
0.9
1.3
0.9
1.3
0.70


YML042W
2.5
1.0
1.2
1.4
1.7
4.8
1.0
0.9
0.29


YNL213C
1.5
0.8
0.9
1.8
1.0
1.7
0.9
1.2
0.70


YOR386W
1.4
1.2
2.4
0.9
1.3
1.2
2.1
1.7
0.46


YBR037C
1.5
0.7
1.2
1.2
1.0
2.7
1.6
1.3
0.60


YCR024C
1.4
0.8
0.9
1.3
1.0
1.2
0.9
1.0
0.32


YDR194C
1.2
0.6
1.2
0.8
1.1
0.8
0.6
0.8
2.19


YER017C
0.9
1.0
1.5
1.1
2.1
1.0
0.9
1.0
0.43


YGL125W
1.6
1.0
1.4
1.0
1.9
1.2
1.2
1.1
0.27


YGR029W
1.2
0.6
1.0
2.0
0.4
1.1
1.1
1.3
0.71


YHL038C
0.8
1.6
1.3
0.6
0.8
0.5
0.9
0.6
1.95


YKL192C
1.1
1.2
1.7
1.5
1.2
2.1
1.0
0.8
1.57


YKR052C
1.3
0.9
1.2
1.1
0.5
2.5
0.8
1.5
1.15


YML078W
2.4
1.2
1.7
1.7
1.0
1.8
1.3
1.6
1.98


YMR056C
1.6
0.9
0.9
1.1
0.7
2.4
1.0
1.1
0.72


YNL005C
1.2
0.9
1.5
1.3
1.0
1.6
0.9
1.5
1.52


YPR047W
1.1
0.9
1.3
1.0
0.8
2.8
1.0
1.5
0.39


YPR134W
1.3
0.9
1.1
1.5
0.7
2.4
1.0
1.2
0.65


YGL191W
1.6
0.9
1.1
1.6
0.7
1.8
1.2
1.7
2.35


YLR038C
1.4
0.6
0.5
1.6
0.7
2.1
1.2
2.1
1.52


YHR008C
2.1
0.7
1.2
1.6
1.7
2.2
0.9
1.0
1.04


YPR037C
0.9
0.9
1.0
1.6
4.1
1.8
1.2
1.7
0.80


YAL039C
1.1
1.4
1.6
1.2
3.3
2.2
1.4
1.1
0.39


YDL181W
0.8
0.9
0.9
1.1
0.4
1.1
1.5
1.4
0.85


YPL215W
1.1
0.7
0.7
1.2
0.6
1.4
1.0
1.1
1.10


YPL262W
1.4
1.1
1.5
1.2
0.6
1.4
1.1
1.2
0.79


YNL256W
0.6
0.6
1.3
0.7
0.9
0.4
0.6
0.6
1.09


YBL030C
1.1
0.9
0.5
0.8
1.8
1.0
1.0
1.1
3.12


YBR221C
1.2
1.3
1.7
0.8
1.1
1.5
0.9
1.0
3.62


YKL141W
1.2
0.8
0.8
1.4
0.6
2.8
0.9
1.8
2.84


YKR066C
1.3
0.9
0.6
1.5
0.6
1.3
0.9
1.1
1.25


YMR083W
1.6
0.7
0.9
0.8
1.3
1.3
0.9
1.1
2.52


YMR203W
2.3
0.7
1.1
0.7
1.2
0.9
0.8
0.7
1.62


YBL099W
2.1
1.0
0.9
0.6
1.0
0.9
0.7
1.2
3.49


YDR178W
2.0
1.3
1.5
1.5
0.7
3.0
1.2
2.3
2.27


YDR298C
1.2
1.1
1.2
1.5
0.8
2.0
1.1
1.6
2.69


YEL024W
0.9
0.8
0.6
1.1
0.6
2.1
1.1
1.5
1.59


YGR082W
1.3
0.8
0.5
0.9
1.2
1.3
0.9
0.8
1.47


YJL133W
1.2
0.8
0.8
0.7
0.9
0.6
0.8
0.7
0.91


YJR077C
1.6
1.0
0.9
0.7
1.5
0.7
1.0
0.8
1.79


YJR121W
0.9
0.8
1.0
0.7
0.9
1.2
1.1
1.4
3.99


YKL148C
1.5
0.8
0.8
0.8
0.6
1.1
0.8
1.0
0.54


YLL041C
1.3
0.8
1.0
1.2
0.4
3.1
1.1
1.7
1.75


YLR304C
1.6
1.0
0.5
0.7
1.6
1.8
0.5
0.7
2.39


YOR142W
1.5
0.8
1.4
0.8
1.1
0.8
0.9
1.0
1.31


YOR176W
1.4
1.3
1.5
0.8
0.8
1.4
1.2
2.1
1.23


YPL135W
1.3
1.1
1.2
1.1
1.5
1.2
1.5
1.7
1.50


YDR529C
0.8
0.6
0.7
1.5
0.5
1.8
1.0
2.3
3.11


YGL018C
1.1
1.0
1.3
1.2
1.1
1.5
0.8
1.0
0.36


YBR003W
1.3
0.8
1.2
0.8
0.7
2.0
1.1
1.3
1.06


YBR044C
1.1
0.8
1.2
0.9
0.9
1.4
0.9
1.3
0.57


YBR091C
0.7
0.8
1.2
1.7
0.9
0.9
1.0
1.0
0.87


YBR185C
1.2
0.7
1.0
1.7
1.0
1.7
0.8
1.3
0.89


YBR282W
0.9
0.8
1.3
1.4
1.1
1.5
0.9
1.2
1.36


YDR347W
0.8
0.8
1.3
1.5
1.0
1.7
0.9
1.2
1.33


YEL039C
1.7
0.6
0.5
1.4
0.4
3.5
0.7
1.1
1.59


YGR076C
1.7
1.0
1.4
2.3
0.5
2.3
0.9
1.5
0.97


YGR174C
1.3
0.9
1.5
1.6
0.7
3.2
1.3
2.3
1.05


YKL003C
1.7
0.7
1.3
2.0
1.0
2.3
1.0
1.2
0.90


YKL016C
1.3
1.0
1.3
1.6
0.7
1.8
1.0
1.7
2.08


YKL170W
0.7
0.8
0.9
1.3
0.8
2.1
1.1
1.4
1.27


YKL194C
1.6
0.6
1.1
1.4
0.8
1.2
1.1
1.1
0.52


YLR395C
1.5
0.6
0.5
1.7
0.4
1.2
1.2
2.3
1.76


YML120C
1.3
0.9
1.2
0.8
0.5
1.5
1.0
1.6
0.74


YOR100C
1.4
0.8
1.0
1.4
4.3
2.8
0.9
0.8
0.32


YOR150W
1.0
0.8
1.0
1.6
0.8
1.6
0.9
1.3
1.11


YOR187W
1.4
0.8
0.7
0.6
1.3
1.6
0.8
1.3
3.12


YJL166W
1.4
0.7
0.8
1.9
0.5
2.3
1.7
4.0
2.31


YMR035W
1.5
0.5
1.4
1.3
1.1
1.5
2.2
2.4
0.96


YBL038W
0.7
0.7
1.0
2.3
0.7
1.8
1.2
1.9
1.56


YDR377W
1.4
0.9
0.7
1.4
0.6
1.8
1.2
2.5
3.00


YGL187C
0.7
0.8
0.7
0.9
0.3
1.4
0.9
2.4
2.73


YCR046C
1.5
1.1
1.5
1.3
1.4
2.8
1.3
1.0
0.63


YML129C
1.2
0.8
1.0
1.4
1.1
2.9
1.3
1.3
1.04


YOL096C
1.2
1.2
1.4
1.4
1.0
2.3
1.2
1.2
0.64


YBR122C
1.2
0.7
0.8
1.2
0.7
1.9
0.9
1.5
1.53


YBR251W
1.5
1.1
1.0
1.6
0.8
3.0
0.9
1.4
1.13


YCR083W
1.8
1.1
1.8
2.4
1.0
3.1
1.3
1.3
0.98


YDL067C
1.4
1.0
0.6
1.4
0.7
1.8
1.2
1.7
1.85


YDR079W
1.3
1.1
1.3
1.5
0.6
2.6
1.1
1.3
1.06


YGR062C
1.6
1.0
1.5
1.2
0.5
1.8
0.9
1.1
0.54


YJL096W
1.2
1.0
0.7
2.1
1.0
2.2
1.1
1.2
1.21


YJL180C
1.4
0.8
1.2
1.4
0.6
2.0
0.9
1.4
1.08


YLR295C
1.3
0.5
0.8
1.2
0.5
2.4
0.9
1.5
1.07


YMR023C
0.8
0.7
1.1
1.6
0.7
2.1
1.1
1.4
0.48


YMR267W
1.0
0.8
0.7
1.0
0.9
2.6
0.9
1.3
0.94


YNL073W
1.1
0.7
1.2
0.7
0.7
1.8
0.8
1.0
0.52


YOR316C
2.4
1.1
1.6
1.0
1.5
2.2
0.8
1.0
0.93


YPL040C
0.9
0.9
1.0
1.1
1.1
2.7
0.8
1.1
0.33


YPL134C
1.7
0.8
1.0
1.4
1.1
3.3
1.3
1.3
0.70










[0034]

4





TABLE 3








DNA repair protein genes
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YFL014W
3.4
5.1
5.7
11.0
1.0
9.3
5.5
3.4
13.1
5.8


YGL163C
0.9
0.8
0.6
4.3
1.5
0.9
1.0
1.4
5.8
2.3


YKL145W
0.8
1.4
1.2
1.0
1.4
2.1
1.6
1.5
3.5
2.7


YIL153W
0.8
1.4
1.3
2.9
1.0
0.9
1.6
0.5
4.3
1.1


YIR002C
0.8
1.1
0.5
0.6
1.2
2.2
1.3
1.2
1.7
1.4


YAL015C
1.2
1.1
1.7
1.9
1.1
0.7
1.2
1.1
4.0
2.7


YBR073W
0.7
1.0
0.9
0.7
1.2
0.7
0.6
1.1
2.5
1.8


YDL200C
1.4
2.0
1.2
1.8
1.1
0.6
1.7
1.5
2.4
1.8


YGL058W
1.1
1.1
0.6
0.7
1.0
1.0
0.0
1.3
3.7
1.8


YIL143C
0.9
0.8
1.1
0.9
0.8
1.4
0.8
0.9
7.1
3.5


YML032C
0.8
0.9
1.1
0.7
1.0
0.9
0.8
0.9
3.0
1.1


YNL250W
0.9
2.2
0.8
1.2
0.8
0.8
1.2
1.3
4.2
2.3


YOR386W
1.0
0.8
1.3
1.5
1.2
3.3
1.8
1.0
4.1
3.0


YBL019W
0.9
9.1
0.7
1.2
1.0
1.0
1.2
1.2
2.6
1.4


YDR369C
1.1
1.1
2.4
1.1
1.0
0.6
0.4
1.0
2.4
1.8


YEL037C
0.9
2.0
0.9
1.0
0.5
0.6
0.8
0.8
2.6
1.2


YER162C
1.0
1.2
1.0
1.1
0.9
0.7
0.5
0.9
2.8
1.6


YGR258C
0.7
0.9
0.7
0.7
1.5
2.2
1.5
0.8
2.5
1.5


YJR052W
1.1
1.0
1.1
1.0
1.0
1.4
1.2
1.7
4.5
2.3


YOR005C
1.2
1.8
1.0
0.8
1.3
1.3
1.4
1.3
2.4
1.5


YPL022W
0.7
0.8
0.7
1.2
0.8
5.2
0.8
1.0
2.1
1.6


YPL164C
1.1
0.7
1.1
1.0
1.2
1.7
0.9
1.0
2.1
2.0


YPL194W
0.9
1.4
0.4
1.1
1.3
1.1
1.5
1.3
9.6
3.1


YPR025C
1.1
0.8
0.6
0.6
1.6
0.9
1.4
1.3
1.9
1.7


YGR180C
3.1
1.1
1.9
1.0
2.0
0.6
0.5
1.0
1.4
1.5


YEL019C
1.1
1.6
0.3
0.7
0.9
1.5
1.2
0.9
0.7
0.7


YLR288C
1.2
0.8
1.6
1.8
1.7
1.2
1.3
1.5
0.8
1.3


YMR284W
1.1
1.0
0.5
2.0
0.8
0.8
0.8
1.1
1.6
1.8


YMR035W
1.2
1.7
1.5
1.7
0.8
1.5
2.3
1.4
1.7
1.6


YOL043C
1.1
0.9
0.8
1.7
1.2
0.8
1.0
0.9
1.0
1.8


YGR231C
1.0
1.2
0.7
1.0
1.3
1.9
2.1
1.1
3.2
2.3


YHR164C
0.9
1.3
0.9
0.7
0.9
1.4
0.8
1.1
1.3
3.1


YJR046W
1.0
1.2
1.2
1.5
0.8
2.0
0.9
0.9
6.0
2.4


YLR103C
0.8
1.5
1.1
0.4
1.0
1.1
1.3
1.4
0.8
0.5


YMR072W
1.1
1.0
1.4
1.0
1.7
1.6
1.4
1.0
3.0
1.2


YDR054C
1.3
1.0
0.7
1.4
0.7
1.9
1.1
1.5
2.9
3.2


YAR007C
0.7
1.9
0.8
0.5
1.5
1.6
0.8
1.1
4.1
1.7


YGL058W
1.1
1.1
0.6
0.7
1.0
1.5
0.0
1.3
3.7
1.8


YIL036W
0.9
1.3
1.3
1.8
0.9
1.8
1.4
1.1
3.6
2.7


YNL213C
1.7
11.6
0.9
1.5
1.3
1.7
1.4
1.8
3.0
1.5


YNL312W
0.9
1.0
1.6
0.7
1.4
1.7
0.5
1.2
3.7
2.5


YNL261W
1.0
1.3
0.6
1.3
0.7
1.3
1.0
1.1
2.3
1.5


YGR180C
3.1
1.1
1.9
1.0
2.0
1.0
0.5
1.0
1.4
1.5


YJL026W
2.5
2.4
2.9
1.0
1.7
1.0
0.5
1.2
1.0
1.1


YDL017W
0.8
2.3
1.2
1.3
1.2
1.1
1.1
1.2
0.8
1.8


YML058W
1.9
1.2
5.8
1.9
0.6
1.3
0.6
0.7
1.1
1.2


YLR233C
1.1
0.9
2.0
2.0
1.2
0.8
0.8
1.1
0.6
0.5


YMR284W
1.1
1.0
0.5
2.0
0.8
1.2
0.8
1.1
1.6
1.8


YGL163C
0.9
0.8
0.6
4.3
1.5
0.9
1.0
1.4
5.8
2.3


YGL127C
1.0
1.9
1.3
1.7
1.3
0.6
1.0
0.9
1.2
1.5


YMR072W
1.1
1.0
1.4
1.0
1.7
2.4
1.4
1.0
3.0
1.2


YGL249W
1.4
0.8
0.5
0.8
1.1
2.5
1.2
0.9
0.3
2.4


YBR272C
0.8
1.8
1.3
1.0
1.1

1.9
1.1
1.7
2.7


YDL059C
2.6
5.1
1.4
1.7
1.2
1.2
1.1
1.2
10.5
7.8


YAR007C
0.7
1.9
0.8
0.5
1.5
0.6
0.8
1.1
4.1
1.7


YBR073W
0.7
1.0
0.9
0.7
1.2
0.7
0.6
1.1
2.5
1.8


YML032C
0.8
0.9
1.1
0.7
1.0
0.9
0.8
0.9
3.0
1.1


YNL250W
0.9
2.2
0.8
1.2
0.8
0.8
1.2
1.3
4.2
2.3


YCR014C
0.8
1.0
0.8
0.6
1.2
1.1
1.1
1.0
2.4
1.0


YDR369C
1.1
1.1
2.4
1.1
1.0
0.6
0.4
1.0
2.4
1.8


YIL072W
0.8
3.1
1.1
2.6
1.5
1.2
1.7
1.4
2.9
2.1


YOR005C
1.2
1.8
1.0
0.8
1.3
1.3
1.4
1.3
2.4
1.5


YPL164C
1.1
0.7
1.1
1.0
1.2
1.7
0.9
1.0
2.1
2.0


YPL194W
0.9
1.4
0.4
1.1
1.3
1.1
1.5
1.3
9.6
3.1


YGR180C
3.1
1.1
1.9
1.0
2.0
0.6
0.5
1.0
1.4
1.5


YEL019C
1.1
1.6
0.3
0.7
0.9
1.5
1.2
0.9
0.7
0.7


YML058W
1.9
1.2
5.8
1.9
0.6
0.6
0.6
0.7
1.1
1.2


YLR288C
1.2
0.8
1.6
1.8
1.7
1.2
1.3
1.5
0.8
1.3


YMR284W
1.1
1.0
0.5
2.0
0.8
0.8
0.8
1.1
1.6
1.8


YMR096W
1.7
1.7
1.1
0.8
1.0
2.2
1.9
2.0
3.3
3.7


YGL091C
2.0
1.8
1.0
1.7
0.8
1.6
1.3
1.8
10.8
6.0











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YFL014W
5.0
4.3
15.2
7.3
6.3
14.2
1.5
8.8
2.14


YGL163C
0.4
0.9
3.1
1.6
1.8
1.0
0.9
0.8
0.26


YKL145W
1.8
1.3
2.7
1.0
1.3
1.2
1.1
1.5
2.29


YIL153W
1.0
1.0
1.2
1.0
2.8
1.3
0.9
0.7
0.32


YIR002C
0.8
1.3
1.2
1.1
1.1
1.4
1.1
1.2
0.58


YAL015C
1.4
1.0
1.2
1.6
0.7
2.0
1.1
1.2
0.61


YBR073W
0.5
0.9
1.4
1.0
1.3
0.8
0.7
0.8
0.63


YDL200C
1.2
1.1
1.1
1.8
0.7
1.8
0.9
1.6
0.79


YGL058W
0.8
1.3
1.0
1.3
1.3
0.6
1.1
0.7
1.07


YIL143C
1.5
0.9
1.7
1.0
1.3
1.1
0.9
0.9
0.56


YML032C
1.0
0.9
1.8
1.0
1.7
1.2
1.0
1.0
0.66


YNL250W
1.0
1.4
1.3
1.6
1.3
1.4
1.0
1.0
0.31


YOR386W
1.4
1.2
2.4
0.9
1.3
1.2
2.1
1.7
0.46


YBL019W
1.0
0.8
0.9
1.1
0.6
1.9
0.8
1.1
0.38


YDR369C
1.1
0.9
0.1
0.7
1.2
0.6
0.8
0.7
1.88


YEL037C
1.0
1.1
2.0
1.0
1.6
0.5
1.0
0.8
0.82


YER162C
0.5
0.4
0.8
0.8
1.0
1.0
1.2
0.9
0.45


YGR258C
0.3
0.9
1.9
1.2
1.1
1.2
1.0
0.9
0.37


YJR052W
1.1
1.1
1.8
1.4
1.4
1.4
1.0
1.3
0.36


YOR005C
1.2
0.9
2.1
1.2
0.8
1.4
1.1
1.0
0.29


YPL022W
0.8
0.7
1.4
0.9
0.9
1.0
0.9
0.9
0.72


YPL164C
1.1
0.9
1.0
0.9
1.3
1.4
1.0
1.0
0.25


YPL194W
0.9
0.9
1.4
1.1
1.4
0.9
1.0
0.8
0.22


YPR025C
0.9
0.7
1.1
1.3
1.1
1.3
1.1
1.5
0.87


YGR180C
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90


YEL019C
1.2
1.0
1.0
1.7
1.5
0.3
0.8
0.9
0.27


YLR288C
1.4
0.6
0.7
1.2
0.9
1.5
1.2
1.3
0.31


YMR284W
1.1
0.6
1.0
1.2
0.7
1.3
1.1
1.3
0.54


YMR035W
1.5
0.5
1.4
1.3
1.1
1.5
2.2
2.4
0.96


YOL043C
1.2
0.8
0.9
1.5
0.6
2.5
1.0
1.0
0.38


YGR231C
1.6
1.3
3.9
2.2
1.3
2.5
1.0
1.5
1.74


YHR164C
0.6
1.2
2.0
1.3
2.2
1.1
0.8
1.0
0.44


YJR046W
0.6
0.9
3.0
1.0
1.1
0.8
0.7
0.7
0.45


YLR103C
0.9
1.6
3.0
1.0
0.8
1.5
1.1
1.4
1.32


YMR072W
1.9
0.8
2.1
1.2
0.8
1.7
0.9
1.9
2.06


YDR054C
1.9
1.0
2.5
1.1
1.6
1.4
0.8
1.4
1.18


YAR007C
0.9
0.9
1.7
1.4
1.2
0.9
0.8
1.0
1.03


YGL058W
0.8
1.3
1.0
1.3
1.3
0.6
1.1
0.7
1.07


YIL036W
1.2
1.2
1.9
1.1
0.8
1.3
1.1
1.3
0.66


YNL213C
1.5
0.8
0.9
1.8
1.0
1.7
0.9
1.2
0.70


YNL312W
1.4
0.9
0.7
1.1
0.8
0.8
1.2
1.1
2.05


YNL261W
0.8
0.8
0.8
1.4
0.7
1.1
0.8
1.0
0.91


YGR180C
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90


YJL026W
1.3
1.0
1.2
1.0
1.1
1.6
1.4
2.1
3.74


YDL017W
0.8
0.8
0.9
1.3
1.3
1.0
0.8
1.0
0.38


YML058W
3.3
0.9
1.4
1.1
2.5
1.3
1.3
1.5
2.14


YLR233C
0.8
0.9
1.0
1.1
1.1
1.1
1.0
1.2
0.43


YMR284W
1.1
0.6
1.0
1.2
0.7
1.3
1.1
1.3
0.54


YGL163C
0.4
0.9
3.1
1.6
1.8
1.0
0.9
0.8
0.26


YGL127C
1.0
1.4
1.7
1.0
1.5
1.3
1.0
1.2
0.54


YMR072W
1.9
0.8
2.1
1.2
0.8
1.7
0.9
1.9
2.06


YGL249W
0.6
0.8
0.8
1.9
0.7
1.4
1.0
1.0
0.20


YBR272C
1.1
0.5
1.3
1.0
0.5
1.7
1.1
1.2
0.52


YDL059C
2.0
1.3
1.7
4.7
0.7
1.5
0.8
0.9
0.63


YAR007C
0.9
0.9
1.7
1.4
1.2
0.9
0.8
1.0
1.03


YBR073W
0.5
0.9
1.4
1.0
1.3
0.8
0.7
0.8
0.63


YML032C
1.0
0.9
1.8
1.0
1.7
1.2
1.0
1.0
0.66


YNL250W
1.0
1.4
1.3
1.6
1.3
1.4
1.0
1.0
0.31


YCR014C
0.8
0.7
1.2
1.0
0.7
1.5
1.0
0.9
0.34


YDR369C
1.1
0.9
0.1
0.7
1.2
0.6
0.8
0.7
1.88


YIL072W
1.8
1.1
1.4
2.0
1.4
1.4
1.0
1.1
0.23


YOR005C
1.2
0.9
2.1
1.2
0.8
1.4
1.1
1.0
0.29


YPL164C
1.1
0.9
1.0
0.9
1.3
1.4
1.0
1.0
0.25


YPL194W
0.9
0.9
1.4
1.1
1.4
0.9
1.0
0.8
0.22


YGR180C
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90


YEL019C
1.2
1.0
1.0
1.7
1.5
0.3
0.8
0.9
0.27


YML058W
3.3
0.9
1.4
1.1
2.5
1.3
1.3
1.5
2.14


YLR288C
1.4
0.6
0.7
1.2
0.9
1.5
1.2
1.3
0.31


YMR284W
1.1
0.6
1.0
1.2
0.7
1.3
1.1
1.3
0.54


YMR096W
1.5
1.4
8.4
4.7
28.9
2.2
2.2
1.0
0.62


YGL091C
2.1
1.2
2.5
3.1
0.7
1.0
1.4
1.8
0.96










[0035]

5





TABLE 4








Energy system protein genes
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YCR107W
12.1
2.6
1.8
1.6
0.7
1.5
1.5
15.6
196.6
34.0


YDL243C
14.5
2.7
2.4
1.0
1.1
2.2
1.6
11.8
64.2
29.6


YFL056C
19.0
2.3
2.3
1.5
0.9
0.6
1.4
18.5
162.3
31.3


YFL057C
20.9
5.9
1.5
1.8
0.9
1.2
1.8
18.0
51.8
46.1


YJR155W
7.6
3.7
1.4
2.5
0.7
1.4
1.7
10.6
38.2
18.8


YNL331C
8.6
3.6
1.3
1.0
1.6
1.8
1.9
13.1
42.6
36.3


YOL165C
10.1
4.5
1.8
0.9
0.9
1.7
1.4
17.8
46.9
23.3


YPL171C
15.2
4.1
3.5
2.2
1.1
1.3
1.7
20.5
60.0
50.6


YDL021W
5.1
1.7
2.4
3.7
1.7
6.5
5.9
2.7
2.5
7.4


YGR043C
2.6
3.7
3.2
7.9
0.9
16.3
6.5
2.6
10.9
8.4


YHR179W
3.3
2.3
2.6
0.7
1.2
3.7
1.9
3.3
3.6
5.8


YJR048W
1.3
0.9
2.2
1.4
0.8
0.5
0.3
0.9
0.5
1.5


YKR097W
1.6
2.4
1.3
3.3
1.1
1.7
3.7
2.5
1.9
3.3


YML087C
1.8
1.6
0.8
2.5
0.9
0.9
1.1
1.3
1.9
4.9


YPL088W
3.3
1.3
0.6
2.5
1.5
7.1
3.7
1.9
0.6
2.8


YDL174C
0.9
1.8
0.9
1.3
0.5
1.7
3.6
0.8
0.5
1.7


YCR012W
1.2
1.5
5.1
1.2
1.1
2.5
1.4
0.8
1.4
1.5


YFR053C
1.8
1.4
3.0
2.2
0.9
3.2
2.1
2.8
0.6
1.1


YGL062W
0.6
1.3
1.1
0.6
0.9
1.0
1.3.
0.8
1.6
2.5


YGR192C
1.4
1.0
3.8
1.0
1.1
1.7
1.7
1.1
0.9
1.3


YGR244C
1.0
1.2
1.6
1.6
0.8
2.6
3.9
1.8
1.4
1.1


YGR254W
1.2
1.3
3.8
1.3
1.2
1.9
1.5
1.4
0.8
1.2


YIL160C
0.8
2.4
2.3
3.5
1.0
1.6
1.1
1.2
3.2
3.8


YJL052W
1.6
0.9
4.0
1.8
0.7
2.4
2.1
1.5
1.6
2.0


YJR009C
1.1
1.7
5.6
1.0
1.2
1.6
1.6
1.1
1.1
1.3


YLR345W
1.4
1.4
1.4
1.2
1.2
1.6
1.2
1.4
4.5
4.0


YMR118C
1.3
2.9
1.4
1.6
1.2
2.0
1.0
1.0
9.3
1.4


YNL071W
0.9
0.9
1.7
1.5
0.6
1.3
1.4
0.9
1.1
1.2


YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4


YPL240C
0.7
1.4
2.4
0.9
1.3
1.2
1.4
1.2
3.5
2.6


YAL060W
1.1
1.8
3.2
2.7
1.2
4.2
3.3
0.9
0.6
2.5


YCL040W
0.9
5.6
10.1
2.0
0.5
3.5
2.9
0.7
0.9
3.0


YDR001C
1.0
2.2
2.6
1.0
1.1
2.2
1.5
0.9
2.2
3.0


YDR231C
1.1
1.6
1.0
1.5
1.1
2.2
1.7
1.3
1.5
1.4


YER178W
0.8
0.9
3.6
1.0
0.7
2.5
1.6
0.8
1.7
1.3


YGR008C
2.4
3.0
1.7
3.2
0.9
2.9
3.7
1.9
3.1
2.4


YGR256W
1.2
1.5
2.3
0.8
0.9
6.2
1.4
2.2
3.4
2.5


YHL008C
0.9
0.5
1.0
1.6
0.8
0.8
0.7
0.9
1.6
1.7


YHR174W
1.1
1.4
3.3
1.2
1.3
1.5
1.6
1.2
1.0
1.5


YIL045W
1.7
1.4
1.9
2.2
1.3
1.7
1.6
1.1
2.1
3.2


YKL035W
1.0
0.9
4.8
1.2
0.8
1.2
0.6
1.0
0.8
1.2


YKL152C
1.4
1.3
1.9
0.9
1.3
1.6
1.5
1.0
0.9
1.5


YML054C
1.5
1.8
1.3
3.4
1.3
1.8
1.2
1.5
4.1
1.8


YML100W
0.8
2.7
10.6
1.4
0.9
2.8
2.2
0.7
1.7
1.4


YML125C
0.8
0.9
0.7
0.7
0.9
1.3
1.0
1.3
2.6
1.6


YMR089C
1.0
1.1
0.9
0.9
0.8
1.2
1.2
1.3
5.6
2.5


YMR105C
2.0
3.0
5.0
4.2
0.9
2.8
2.8
1.1
0.6
2.9


YNL237W
1.3
1.3
1.5
1.0
1.5
4.6
4.9
1.1
0.9
2.1


YOL126C
1.1
0.8
1.0
1.6
0.7
1.5
1.4
0.9
0.8
2.4


YOR347C
0.9
0.9
2.1
2.2
0.7
0.9
0.9
0.8
0.5
0.9


YPR026W
0.9
1.2
5.0
1.3
0.8

1.3
1.0
0.9
3.1


YAL038W
1.0
1.0
3.0
1.4
1.4
1.3
0.9
1.1
0.1
1.1


YDR380W
0.8
0.8
0.8
1.7
1.1
0.4
0.5
0.2
0.2
0.3


YLR273C
1.5
1.0
1.3
2.4

1.2
1.2
1.3
2.8
2.4


YGR207C
1.5
1.1
1.0
1.1
1.5
2.8
1.7
1.9
2.1
2.6


YNL037C
1.4
1.8
1.7
1.1
1.7
2.8
2.8
1.0
0.6
3.2


YOR136W
1.0
0.9
3.5
1.0
1.5
3.9
3.2
1.1
0.3
3.4


YPL271W
1.2
3.2
4.1
1.2
1.4
3.3
1.2
0.9
0.6
1.2


YAL054C
1.2
1.1
1.4
1.6
1.1
2.2
1.1
1.1
8.9
4.1


YEL011W
2.0
1.6
1.7
6.3
1.1
2.8
2.7
0.9
2.5
1.6


YFR015C
1.2
0.8
3.2
2.1
1.2
3.0
7.3
0.7
0.3
1.8


YGL253W
0.8
1.0
3.2
0.7
1.3
2.4
1.7
1.1
0.3
1.4


YIL111W
1.9
1.0
1.8
2.7

2.6
3.2
1.2
1.6
1.1


YKL150W
1.1
2.0
3.0
1.4
1.4
2.3
2.4
1.3
1.1
1.3


YPR006C
1.9
1.5
0.5
1.9
2.0
2.4
2.8
1.5
1.5
3.9


YBR145W
1.5
0.7
2.8
0.9
1.1
11.5
58.8
1.0
0.1
1.1


YBR299W
2.0
0.9
1.1
3.5
1.6
0.8
3.6
2.2
1.1
5.3


YEL020C
1.0
1.5
0.8
2.9
1.5
1.3
2.4
1.2
1.4
1.1


YGL134W
1.2
1.3
0.5
0.8
1.4
1.2
2.3
1.4
1.1
1.4


YOL157C
1.0
1.1
1.3
2.5
1.4
0.9
2.7
1.4
2.3
4.8


YBR126C
0.8
1.9
5.6
1.2
0.7
2.9
2.3
0.6
1.7


YCR005C
1.2
1.9
2.0
1.2
0.9
1.6
4.4
1.2
1.5
1.5


YIL172C
1.1
1.1
1.6
1.7

1.3
2.5
1.6
2.8
7.1


YOR221C
0.8
1.0
0.9
1.1
1.7
0.8
2.1
0.9
1.4
1.7


YBR196C
0.8
0.6
3.9
1.4
0.8
0.8
1.4
1.1
0.3
0.9


YEL047C
1.3
1.9
3.2
1.2
0.8
0.6
1.3
1.0
2.7
2.3


YMR318C
1.8
2.4
2.2
0.7
1.2
2.1
0.8
3.6
2.3
4.8


YER061C
0.9
0.9
1.2
2.5
0.8
0.4
0.9
0.7
0.3
0.7


YJL045W
1.8
2.2
1.6
5.3
0.7
0.6
0.7
0.9
9.7
1.6


YLL009C
1.0
1.2
0.6
1.9
1.5
1.2
1.7
1.0
1.3
1.7


YPR160W
1.4
3.8
3.6
3.3
0.7
4.5
1.8
0.9
0.9
1.3


YDL085W
1.2
1.9
1.2
2.0
1.2
1.2
1.4
1.0
7.8
3.4


YJL221C
1.1
1.0
1.1
1.3
0.9
6.6
2.5
1.8
2.7
4.4


YKL085W
1.5
2.3
1.6
1.2
1.2
1.9
1.5
1.2
1.9
3.0


YLR174W
1.2
1.5
1.7
2.1
0.9
0.9
1.6
1.1
2.5
8.3


YNL009W
1.1
1.9
2.0
1.4
1.4
1.1
1.2
1.1
1.4
3.3


YNL117W
0.9
4.7
1.7
0.8
0.8

1.1
1.7
12.8
4.4


YAL061W
1.7
2.4
3.3
3.8
1.0
1.0
2.0
0.8
5.5
1.4


YBR117C
0.8
1.6
1.5
1.4
0.9
2.3
1.0
0.7
5.9
1.5


YEL071W
1.1
1.6
2.6
0.4
1.3
1.9
2.0
1.2
3.6
2.8


YGR112W
1.0
2.9
1.1
1.3
0.9
1.1
1.3
1.3
2.6
1.3


YLR164W
1.0
2.4
0.3
1.0
1.2
1.2
1.1
1.2
5.3
2.0


YNR032W
1.0
1.5
1.0
2.1
1.5
1.0
1.1
1.0
6.2
2.4


YPL031C
0.9
2.0
1.4
0.8
1.5
1.8
1.6
1.0
5.7
1.4


YPR048W
1.3
2.0
0.9
1.1
0.9
0.6
0.9
1.5
4.0
2.1


YBL058W
0.9
1.5
0.5
1.1
1.6
0.9
1.5
1.2
2.6
2.1


YBR001C
0.9
1.4
1.1
1.4
0.9
1.1
0.9
1.3
2.3
2.1


YCR105W
2.2
1.2
1.2
3.0
0.9
1.0
1.0
1.4
2.0
3.9


YIR031C
0.9
1.6
0.6
0.6
1.6
1.7
1.4
1.0
2.6
1.0


YGL191W
2.3
1.6
1.4
1.8
0.9
1.6
1.0
1.6
1.1
1.3


YLR038C
2.6
1.1
0.6
2.1
1.8
1.2
1.0
1.4
0.4
0.9


YGR087C
1.0
15.0
1.7
0.6
1.0
1.1
1.0
0.8
0.2
0.9


YGL256W
0.9
5.3
1.1
1.3
0.7
0.7
0.5
1.0
0.4
1.2


YDL181W
1.4
1.8
1.9
1.8
1.7
1.2
1.1
0.6
0.7
0.8


YPL262W
1.1
1.7
3.8
1.2
0.6
1.6
1.3
1.0
1.4
5.8


YLR377C
1.1
2.6
1.8
1.2
1.0
0.7
0.9
0.7
1.8
1.6


YBR221C
0.8
0.7
3.2
1.5
1.3
1.7
1.5
0.8
1.0
1.3


YKL141W
1.6
1.1
4.7
1.7
1.5
1.2
0.5
0.8
0.8
0.5


YLR134W
0.9
0.6
2.3
0.8
1.3
2.5
1.1
0.8
0.1
0.7


YLR258W
1.7
1.0
4.2
3.5
0.9
1.8
1.8
0.9
0.8
1.3


YOR178C
1.4
1.3
4.8
2.3
1.0
2.7
0.9
0.9
0.2
1.7


YBL099W
0.8
0.9
3.1
1.4
1.0
0.9
0.9
0.8
0.9
0.7


YDR050C
1.9
1.3
2.3
1.8
0.9
1.7
1.5
1.3
0.4
1.3


YDR178W
2.0
2.0
3.4
2.2
0.9
2.1
0.6
0.9
0.9
0.8


YDR298C
1.3
1.2
2.6
1.3
1.3
1.2
1.0
1.2
1.0
1.6


YEL024W
1.5
0.9
3.8
1.1
1.3
1.1
0.7
1.0
0.7
0.6


YJL121C
1.0
0.5
1.9
0.8
1.0
1.1
0.7
1.0
0.1
0.4


YJR121W
1.2
1.1
3.3
1.0
0.8
1.5
1.0
0.7
0.8
1.3


YKL060C
1.7
0.8
2.5
1.0
1.6
1.3
1.2
1.1
0.3
0.8


YKL148C
0.9
0.8
3.7
0.7
0.8
0.5
0.6
0.8
1.7
1.7


YLL041C
1.5
0.5
4.6
1.0
1.6
1.2
0.3
0.8
0.7
0.8


YLR044C
0.8
0.6
2.2
0.9
1.7
1.5
1.3
0.7
0.0
1.2


YLR284C
0.9
1.0
3.8
1.9
1.6
0.9
0.8
1.2
0.9
0.9


YLR304C
0.7
0.6
5.0
0.7
0.6
1.9
0.6
0.6
0.1
2.2


YLR354C
1.2
2.5
2.3
1.5
1.6
1.5
1.1
1.4
0.4
0.9


YMR205C
0.5
0.7
2.3
0.8
1.2
1.2
0.9
0.7
0.3
0.8


YMR261C
0.8
1.6
3.6
0.8
0.9
0.6
1.3
0.7
1.6
1.3


YMR323W
0.8
1.1
2.9
1.1
0.7
0.4
1.1
0.8
0.5
1.3


YOL086C
1.1
0.5
2.2
1.1
1.9
1.7
1.9
0.8
0.1
1.2


YOR142W
1.3
1.2
3.4
1.0
1.4
1.6
1.0
0.8
1.1
1.5


YPL061W
0.4
1.4
5.0
1.3
1.6
1.7
0.5
0.8
1.3
0.7


YDL107W
1.3
1.3
1.0
2.2
1.0
1.3
1.8
1.8
1.2
1.8


YDR529C
1.8
1.0
0.9
3.2
1.2
0.8
0.5
1.3
0.5
0.6


YGL018C
1.5
1.0
1.8
3.0
1.1
0.4
1.1
0.8
0.5
1.4


YBR185C
1.5
1.0
1.3
2.0
0.8
1.2
1.2
1.1
0.9
1.6


YEL039C
1.1
0.7
1.3
5.1
0.9
1.5
0.6
1.1
1.2
1.2


YGR174C
1.1
1.6
0.6
2.4
1.0
1.4
1.0
1.6
1.8
0.7


YKL016C
1.5
1.3
0.7
1.7
1.5
0.8
1.5
1.6
1.3
1.8


YLR395C
1.8
1.3
2.2
1.9
0.7
0.4

1.0
1.0
0.9


YML120C
1.1
1.2
1.9
1.9
0.6
0.6
0.8
0.9
1.3
1.5


YMR073C
1.1
1.1
1.2
1.5
0.8
0.9
1.0
1.1
1.2
1.2


YOR388C
1.0
1.6
1.3
4.7
1.3
1.4
1.0
0.7
0.1
1.4


YPL275W
0.6
1.5
1.3
5.1
1.2
1.0
1.1
1.0
0.2
1.2


YPL276W
1.2
1.5
1.6
3.0
1.5
1.1
1.2
0.9
−0.2
1.8


YGL205W
1.0
0.9
0.7
0.8
1.1
1.6
0.8
1.2
0.5
0.6


YJL166W
2.1
1.5
1.6
1.3
1.6
0.7
0.8
1.4
1.3
1.2


YNL202W
0.7
1.3
1.2
1.7
0.9
2.0
0.9
1.2
1.3
1.1


YDR377W
1.3
1.1
1.3
1.4
1.9
1.3
1.1
1.3
1.0
0.9


YGL187C
1.5
0.8
1.6
1.8
1.3
1.1
0.6
0.7
0.6
0.6


YJL216C
1.1
4.7
2.2
0.9
0.8

1.5
1.9
1.5
1.3


YKR009C
1.0
1.2
1.5
0.9
1.0
1.8
1.0
0.9
2.4
2.1


YCR046C
1.0
1.2
1.2
1.6
1.0
0.8
1.2
0.9
1.9
1.4


YML129C
1.1
0.9
0.9
1.2
1.7
1.7
1.8
1.2
1.4
2.2


YPR184W
1.2
1.4
5.7
2.2
0.9
1.5
1.3
0.7
1.9
3.2


YDL067C
1.8
1.0
1.6
1.3
2.0
0.9
0.8
1.1
0.9
0.9


YDL078C
0.7
1.1
1.2
0.8
1.3
1.1
1.7
1.0
1.1
1.0


YDR079W
1.3
1.1
0.8
1.1
1.2
1.7
1.3
2.6
0.9
0.8


YGR062C
0.9
1.0
0.7
1.4
0.7
0.9
1.3
0.8
1.0
1.4


YKR058W
1.3
0.9
1.4
1.9
0.8
1.4
1.4
1.5
1.3
1.2


YLR295C
1.5
1.1
1.1
1.7
2.2
1.1
1.1
1.2
1.4
1.2


YMR267W
0.8
1.8
0.7
0.9
1.0
1.4
1.2
1.5
0.4
0.8











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YCR107W
23.0
0.9
4.0
8.3
4.8
3.1
1.3
1.1
0.59


YDL243C
19.6
1.1
4.1
12.0
4.2
3.0
1.8
1.5
0.76


YFL056C
68.3
1.0
4.7
7.8
5.0
3.4
1.0
1.1
0.55


YFL057C
27.7
1.0
4.1
23.4
3.1
3.9
1.6
1.3
0.71


YJR155W
15.4
1.0
5.7
9.4
2.6
5.6
1.3
1.4
0.64


YNL331C
21.8
0.9
3.1
7.5
2.3
4.0
1.7
1.3
0.58


YOL165C
17.6
0.8
3.7
9.1
3.0
1.8
1.6
1.0
0.69


YPL171C
37.0
1.4
2.4
9.3
1.4
1.2
2.4
1.5
0.47


YDL021W
4.7
2.4
5.3
3.7
0.7
7.3
1.9
3.2
0.47


YGR043C
3.6
3.3
6.9
4.1
3.0
13.7
1.6
4.8
0.66


YHR179W
2.0
2.2
2.6
5.8
2.7
1.0
1.9
1.6
2.69


YJR048W
1.0
0.8
0.4
2.5
0.6
1.5
1.2
1.2
1.19


YKR097W
0.8
1.8
17.5
2.1
2.5
2.2
1.1
1.5
0.16


YML087C
1.6
0.8
1.5
2.1
0.3
2.0
0.7
0.8
0.52


YPL088W
1.1
3.6
4.8
1.6
3.2
4.3
9.1
8.3
0.69


YDL174C
0.9
2.8
5.9
1.1
0.6
5.1
2.2
4.0
0.63


YCR012W
1.8
1.2
4.1
0.9
1.4
1.4
0.8
1.3
4.48


YFR053C
1.5
1.7
3.0
0.6
0.6
3.0
1.4
2.2
4.17


YGL062W
0.7
1.6
4.5
1.2
2.7
1.5
1.1
0.9
0.77


YGR192C
2.3
2.2
3.4
1.0
1.9
1.1
1.1
1.3
7.49


YGR244C
1.8
1.9
2.6
1.2
2.0
2.6
1.9
3.1
1.12


YGR254W
1.3
1.7
3.1
0.6
2.4
1.4
1.3
1.2
7.01


YIL160C
2.4
1.0
2.3
1.5
5.6
8.8
2.4
3.0
0.27


YJL052W
4.3
2.4
5.6
1.3
2.3
2.3
1.2
1.9
6.19


YJR009C
1.1
1.5
2.7
1.0
2.1
1.5
1.1
1.3
5.86


YLR345W
2.5
1.6
3.5
1.5
1.0
1.2
1.2
1.4
2.65


YMR118C
0.7
0.8
4.2
0.9
0.9
8.1
0.8
1.0
0.38


YNL071W
1.6
1.3
2.5
0.8
1.1
1.1
1.0
1.2
1.61


YNL241C
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68


YPL240C
1.0
0.8
2.9
0.7
1.2
0.7
0.8
1.0
4.83


YAL060W
2.4
0.8
2.2
0.9
0.9
3.2
1.1
1.8
2.39


YCL040W
8.2
2.3
5.6
0.7
3.4
3.1
1.4
1.7
1.98


YDR001C
0.7
1.1
2.8
1.0
4.4
1.9
1.1
1.6
0.75


YDR231C
1.3
1.1
2.4
1.5
1.0
3.0
1.2
1.3
0.92


YER178W
2.5
1.3
2.4
0.9
1.8
1.0
1.1
0.9
2.18


YGR008C
2.6
2.0
3.4
1.3
1.5
2.3
1.7
4.2
3.03


YGR256W
2.7
1.5
3.9
1.1
2.7
5.3
1.1
0.8
0.94


YHL008C
1.4
0.8
1.8
1.0
1.8
0.9
0.8
0.9
0.40


YHR174W
1.4
1.5
3.6
0.6
2.0
1.1
1.0
1.2
7.34


YIL045W
1.2
1.5
2.0
1.6
0.6
2.9
1.1
1.8
0.37


YKL035W
2.1
1.0
2.0
0.6
1.0
1.5
1.0
1.9
2.54


YKL152C
1.7
1.5
2.7
1.0
1.8
2.0
1.1
1.7
3.28


YML054C
1.4
1.8
2.8
2.1
1.1
7.8
1.1
1.6
0.25


YML100W
3.2
1.2
3.8
1.2
1.8
2.2
1.0
1.5
0.88


YML125C
1.0
1.0
2.2
1.6
1.9
0.7
1.2
0.9
2.21


YMR089C
1.3
0.8
2.3
0.9
1.8
1.1
0.9
1.1
0.69


YMR105C
3.0
1.7
3.3
1.0
0.9
2.0
1.6
2.6
1.21


YNL237W
1.5
1.8
3.2
1.3
1.6
4.4
1.3
1.1
0.21


YOL126C
1.8
1.1
2.6
1.2
1.4
2.5
1.6
2.4
0.59


YOR347C
1.4
1.2
1.8
0.9
2.0
1.4
1.7
1.3
1.31


YPR026W
1.6
1.2
2.3
1.5
3.1
2.5
0.9
1.3
0.26


YAL038W
1.0
1.2
1.8
0.5
3.1
0.9
1.0
1.0
7.02


YDR380W
0.4
0.4
0.4
0.6
2.4
0.2
0.8
0.8
1.04


YLR273C
1.4
0.9
1.7
1.3
2.6
1.5
1.0
1.0
0.20


YGR207C
1.4
1.1
1.0
2.2
0.6
1.8
1.2
1.8
1.49


YNL037C
1.4
1.3
1.9
1.3
0.9
1.4
0.9
1.3
2.05


YOR136W
1.4
1.2
1.5
0.9
1.2
1.3
0.8
1.3
3.20


YPL271W
1.7
0.8
1.2
1.3
0.8
1.4
1.2
1.3
1.34


YAL054C
1.3
1.0
1.8
1.3
0.9
2.5
1.5
1.4
0.24


YEL011W
3.7
1.5
1.5
1.5
0.4
2.4
1.4
2.5
0.89


YFR015C
3.9
0.4
2.5
3.1
0.4
2.4
1.3
1.2
0.66


YGL253W
1.0
1.2
1.5
0.5
0.8
0.4
0.7
0.8
4.63


YIL111W
2.1
0.9
1.7
1.5
1.1
2.5
1.9
3.9
1.52


YKL150W
1.9
1.2
1.8
1.4
0.9
6.1
1.2
2.7
2.20


YPR006C
2.4
1.1
1.8
1.2
0.7
1.6
1.8
2.1
0.46


YBR145W
1.1
1.0
2.0
2.2
1.2
3.6
1.7
2.0
2.17


YBR299W
2.4
1.2
0.7
1.4
0.6
3.9
1.0
1.1
0.32


YEL020C
1.3
0.8
1.2
1.0
1.4
2.1
1.2
1.3
0.31


YGL134W
1.1
0.9
0.7
1.1
0.5
1.7
0.9
1.3
0.53


YOL157C
1.2
1.2
1.4
1.2
1.1
3.5
1.4
1.3
0.41


YBR126C
1.1
1.3
2.1
0.7
1.0
1.7
1.5
1.3
1.96


YCR005C
2.1
0.5
0.7
0.8
0.7
0.7
1.6
1.7
2.38


YIL172C
1.0
1.4
2.0
1.3
1.4
2.8
1.1
1.2
0.42


YOR221C
1.1
0.8
1.0
1.1
1.0
1.4
0.9
1.2
0.39


YBR196C
2.3
1.0
1.4
0.5
1.9
1.1
0.8
1.0
6.60


YEL047C
4.2
1.2
1.6
1.1
1.0
1.3
0.9
1.0
1.02


YMR318C
3.6
0.8
1.8
1.7
1.5
1.1
1.1
1.1
3.17


YER061C
2.2
0.7
0.9
1.0
0.8
1.8
1.2
1.2
0.84


YJL045W
2.3
1.1
1.6
1.2
3.4
2.4
0.9
0.9
0.42


YLL009C
3.5
0.7
0.9
1.4
1.1
2.8
0.9
1.2
1.66


YPR160W
4.4
2.1
2.2
1.1
1.4
5.3
1.0
2.9
1.42


YDL085W
2.7
0.8
1.7
1.2
0.7
4.5
0.9
0.9
0.23


YJL221C
0.8
1.1
1.4
1.1
1.1
3.3
1.1
1.4
0.41


YKL085W
1.8
0.8
1.5
1.0
0.5
1.7
0.9
1.3
2.16


YLR174W
1.3
1.3
1.8
1.7
0.8
4.6
0.9
1.2
0.41


YNL009W
1.3
0.9
1.3
1.3
2.7
3.3
1.2
2.3
0.45


YNL117W
1.4
0.7
1.3
2.0
2.6
1.6
1.1
0.9
0.24


YAL061W
4.1
1.1
1.4
0.7
0.6
1.1
1.4
1.2
0.88


YBR117C
0.4
0.8
2.1
0.9
1.0
12.0
0.7
0.7
0.49


YEL071W
2.1
0.9
1.6
1.2
1.6
1.2
1.1
1.2
1.13


YGR112W
1.3
0.7
1.1
1.1
1.2
2.8
0.9
1.2
0.31


YLR164W
3.2
0.7
1.0
1.5
0.7
11.0
1.5
1.2
0.31


YNR032W
1.4
0.6
1.3
1.4
0.9
1.0
1.2
1.3
0.71


YPL031C
1.4
0.8
1.6
0.9
0.7
2.0
1.4
1.2
0.49


YPR048W
1.0
0.8
0.6
1.2
0.6
0.8
0.7
0.8
0.75


YBL058W
1.3
0.8
1.6
1.3
1.8
1.8
1.0
1.4
1.42


YBR001C
1.0
1.0
2.0
1.2
1.8
1.4
1.0
1.6
0.61


YCR105W
2.3
0.9
1.9
1.9
3.1
1.3
1.3
1.1
0.36


YIR031C
1.2
0.8
1.0
1.2
0.8
0.7
0.9
0.8
0.44


YGL191W
1.6
0.9
1.1
1.6
0.7
1.8
1.2
1.7
2.35


YLR038C
1.4
0.6
0.5
1.6
0.7
2.1
1.2
2.1
1.52


YGR087C
0.8
1.2
1.2
0.7
3.5
0.6
1.0
0.6
1.88


YGL256W
1.0
0.9
0.8
0.9
1.0
0.7
0.7
0.8
0.90


YDL181W
0.8
0.9
0.9
1.1
0.4
1.1
1.5
1.4
0.85


YPL262W
1.4
1.1
1.5
1.2
0.6
1.4
1.1
1.2
0.79


YLR377C
0.6
0.6
1.2
2.9
0.8
2.7
0.9
1.4
0.14


YBR221C
1.2
1.3
1.7
0.8
1.1
1.5
0.9
1.0
3.62


YKL141W
1.2
0.8
0.8
1.4
0.6
2.8
0.9
1.8
2.84


YLR134W
1.1
1.2
1.5
0.6
1.7
0.5
0.6
0.8
3.47


YLR258W
1.2
0.9
1.4
1.2
0.6
1.7
1.0
2.0
1.36


YOR178C
4.1
1.7
1.0
1.0
1.1
1.7
1.0
1.5
0.56


YBL099W
2.1
1.0
0.9
0.6
1.0
0.9
0.7
1.2
3.49


YDR050C
2.0
1.4
2.0
1.2
1.9
1.3
1.1
2.3
6.26


YDR178W
2.0
1.3
1.5
1.5
0.7
3.0
1.2
2.3
2.27


YDR298C
1.2
1.1
1.2
1.5
0.8
2.0
1.1
1.6
2.69


YEL024W
0.9
0.8
0.6
1.1
0.6
2.1
1.1
1.5
1.59


YJL121C
1.1
0.6
0.7
0.9
1.0
0.6
1.1
1.0
1.00


YJR121W
0.9
0.8
1.0
0.7
0.9
1.2
1.1
1.4
3.99


YKL060C
2.1
1.3
1.2
0.8
1.6
1.5
1.2
1.7
6.01


YKL148C
1.5
0.8
0.8
0.8
0.6
1.1
0.8
1.0
0.54


YLL041C
1.3
0.8
1.0
1.2
0.4
3.1
1.1
1.7
1.75


YLR044C
1.1
1.4
1.7
0.5
2.2
0.6
0.9
0.9
5.16


YLR284C
1.5
0.6
0.8
1.3
1.0
4.5
2.9
8.1
0.84


YLR304C
1.6
1.0
0.5
0.7
1.6
1.8
0.5
0.7
2.39


YLR354C
1.7
1.2
1.0
0.9
2.4
1.3
1.0
1.5
4.53


YMR205C
1.0
1.1
1.3
0.5
0.9
0.9
0.6
0.5
4.75


YMR261C
0.8
0.9
1.6
0.6
0.8
1.6
0.7
1.1
0.78


YMR323W
2.5
1.2
1.8
1.2
37.3
0.6
1.1
0.6
1.04


YOL086C
2.6
1.3
1.7
0.6
1.6
1.4
1.1
1.3
4.19


YOR142W
1.5
0.8
1.4
0.8
1.1
0.8
0.9
1.0
1.31


YPL061W
1.1
1.0
1.1
0.6
1.7
1.0
1.6
2.6
3.23


YDL107W
1.0
1.0
1.2
1.5
1.0
2.0
1.1
1.5
0.51


YDR529C
0.8
0.6
0.7
1.5
0.5
1.8
1.0
2.3
3.11


YGL018C
1.1
1.0
1.3
1.2
1.1
1.5
0.8
1.0
0.36


YBR185C
1.2
0.7
1.0
1.7
1.0
1.7
0.8
1.3
0.89


YEL039C
1.7
0.6
0.5
1.4
0.4
3.5
0.7
1.1
1.59


YGR174C
1.3
0.9
1.5
1.6
0.7
3.2
1.3
2.3
1.05


YKL016C
1.3
1.0
1.3
1.6
0.7
1.8
1.0
1.7
2.08


YLR395C
1.5
0.6
0.5
1.7
0.4
1.2
1.2
2.3
1.76


YML120C
1.3
0.9
1.2
0.8
0.5
1.5
1.0
1.6
0.74


YMR073C
0.9
0.8
1.2
2.0
0.9
1.5
0.8
1.2
0.69


YOR388C
1.3
0.7
1.1
1.3
4.0
0.8
1.0
0.9
0.21


YPL275W
0.9
0.6
1.0
1.0
1.4
0.9
1.0
1.0
0.28


YPL276W
−0.4
0.6
0.9
0.9
1.0
0.6
1.1
0.8
0.22


YGL205W
0.4
1.1
1.0
1.0
2.0
4.1
3.9
9.1
0.24


YJL166W
1.4
0.7
0.8
1.9
0.5
2.3
1.7
4.0
2.31


YNL202W
1.2
0.9
1.8
1.0
1.4
4.2
2.4
3.3
0.47


YDR377W
1.4
0.9
0.7
1.4
0.6
1.8
1.2
2.5
3.00


YGL187C
0.7
0.8
0.7
0.9
0.3
1.4
0.9
2.4
2.73


YJL216C
1.1
1.0
1.1
1.1
1.2
1.5
1.2
2.0
0.25


YKR009C
1.2
1.0
1.8
1.0
1.0
4.6
1.9
2.5
0.27


YCR046C
1.5
1.1
1.5
1.3
1.4
2.8
1.3
1.0
0.63


YML129C
1.2
0.8
1.0
1.4
1.1
2.9
1.3
1.3
1.04


YPR184W
3.6
1.4
2.5
1.3
1.5
3.1
1.0
1.7
0.37


YDL067C
1.4
1.0
0.6
1.4
0.7
1.8
1.2
1.7
1.85


YDL078C
1.7
0.8
1.0
0.8
0.5
2.2
1.1
2.0
1.65


YDR079W
1.3
1.1
1.3
1.5
0.6
2.6
1.1
1.3
1.06


YGR062C
1.6
1.0
1.5
1.2
0.5
1.8
0.9
1.1
0.54


YKR058W
1.5
0.9
0.7
1.3
0.5
2.6
0.8
1.6
0.73


YLR295C
1.3
0.5
0.8
1.2
0.5
2.4
0.9
1.5
1.07


YMR267W
1.0
0.8
0.7
1.0
0.9
2.6
0.9
1.3
0.94










[0036]

6





TABLE 5








Transport facilitation protein genes
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YBR008C
3.0
2.4
4.9
0.7
0.9
1.0
0.9
2.8
54.6
21.1


YBR296C
7.0
4.3
2.2
2.5
1.4
1.4
0.2
1.1
0.4
1.8


YDR406W
0.8
1.2
3.1
1.1
1.0
5.9
1.8
0.6
1.1
1.7


YOR153W
1.6
0.9
5.1
1.1
1.0
7.4
2.6
0.5
3.2
1.2


YGR281W
1.2
1.0
1.3
2.2
0.6
1.9
0.9
0.7
2.7
1.4


YHL047C
0.6
4.4
1.0
1.0
1.2
8.4
16.8
1.5
1.2
11.9


YBR294W
6.3
14.4
0.9
2.6
1.4
1.2
1.1
1.0
5.2
5.2


YGL006W
2.5
1.3
1.3
2.6
1.0
1.0
1.3
0.9
3.0
1.2


YGR197C
1.1
2.4
2.5
1.0
0.7
0.5
1.3
0.8
16.7
3.2


YJL034W
0.7
1.7
3.0
0.8
1.2
1.1
1.3
1.5
2.8
1.1


YNL055C
1.1
1.8
5.5
2.0
0.9
2.6
1.2
0.7
1.1
1.0


YBR052C
1.6
1.6
1.5
2.6
1.4
2.1
3.0
1.3
2.3
2.5


YBR207W
0.8
1.7
0.8
2.0
1.7
1.6
4.3
0.9
1.7
2.2


YBR293W
1.9
3.1
1.0
1.8
0.8
0.9
0.9
0.9
5.5
2.4


YDL198C
1.4
1.0
2.1
1.4
0.7
0.8
1.0
1.1
1.9
2.7


YDL245C
1.0
2.4
1.6
2.2
1.3
1.1
1.2
1.2
0.4
2.8


YDR497C
0.7
0.5
0.6
1.3
0.7
0.6
0.5
0.6
0.4
0.8


YER053C
1.6
1.8
1.9
1.7
0.6
2.8
2.8
1.3
1.3
3.9


YFL041W
0.7
1.6
1.4
1.2
1.2
2.0
3.4
1.0
0.8
5.1


YGR055W
2.5
5.7
12.0
0.7
1.3
1.1
0.6
1.1
5.0
2.4


YJL219W
1.2
2.5
3.1
1.6
1.2
1.5
0.9
1.5
4.0
2.3


YJR106W
0.9
3.8
1.5
1.1
0.9
1.2
1.0
0.9
2.0
1.6


YKL146W
0.8
1.3
1.3
0.9
1.0
1.3
0.9
0.8
4.6
2.8


YLL028W
0.6
0.9
4.6
0.5
0.9
1.7
1.0
0.7
1.2
2.3


YLR348C
1.1
4.5
1.2
1.2
0.9
1.9
0.9
0.9
2.1
1.3


YOL119C
2.6
4.8
1.5
2.3
1.5
0.9
2.2
2.0
5.0
7.4


YOL163W
1.5
3.2
2.1
3.3
0.9
0.5
0.9
1.1
7.5
6.2


YOR035C
1.2
1.2
0.3
1.2
1.0
1.9
1.3
1.0
1.3
1.7


YOR130C
0.8
1.7
1.4
1.0
1.8
1.6
1.3
0.8
2.0
1.7


YOR273C
0.7
1.0
1.7
1.0
1.1
0.4
0.4
0.6
0.6
0.5


YOR332W
1.1
1.0
1.0
1.0
0.9
1.8
0.9
1.5
1.8
1.1


YCR098C
1.6
3.0
1.7
2.0
1.4
1.6
1.2
1.0
1.4
2.4


YGR138C
1.1
1.6
1.0
1.2
0.8
0.8
0.7
1.0
0.5
1.0


YBR295W
1.4
1.5
3.3
1.1
0.8

1.6
0.9
1.2
3.3


YGL255W
0.7
0.9
0.9
0.8
1.4
1.1
1.0
0.7
0.3
5.0


YHL035C
0.7
1.3
0.9
1.9
0.9
4.1
1.7
1.1
0.6
4.6


YIL022W
0.8
0.7
1.1
1.6
0.8
1.2
0.7
0.8
1.1
1.3


YLR378C
0.7
0.9
2.6
0.5
1.0
1.2
0.7
0.5
1.1
0.7


YCL038C
1.6
1.6
1.4
1.6
1.2
3.2
1.5
1.2
1.1
0.9


YFL054C
1.6
1.1
1.4
2.2
1.3
2.4
1.1
1.5
2.0
2.3


YHL040C
1.6
4.9
1.5
0.4
1.1
7.3
4.0
1.5
1.1
11.3


YKR039W
1.4
3.5
1.3
1.7
1.0
2.8
1.0
1.0
1.9
2.0


YPL271W
1.2
3.2
4.1
1.2
1.4
3.3
1.2
0.9
0.6
1.2


YBR068C
1.1
1.0
1.9
2.5
1.4
1.9

1.0
0.8
2.5


YCR037C
0.7
1.0
0.8
0.8
1.3
1.8
1.0
0.7
0.6
0.6


YDL128W
0.8
1.1
2.1
1.0
1.0
2.3
0.9
0.8
0.5
0.7


YDR270W
0.7
1.5
1.4
1.3
1.0
2.2
1.7
1.2
2.9
3.6


YEL065W
0.3
3.8
1.2
0.4
1.4
2.3
4.3
0.9
0.1
4.9


YGL008C
0.6
0.7
3.1
0.9
0.8
1.9
1.4
0.7
0.0
0.4


YGL104C
0.8
2.0
2.1
1.8
1.0
2.1
1.2
0.8
4.6
2.1


YGL167C
0.9
0.7
1.6
1.3
1.2
2.0
1.2
0.8
1.3
1.1


YGR065C
0.8
1.5
2.6
1.1
1.2
2.4
2.4
1.0
1.2
2.6


YHR092C
2.3
1.0
7.5
2.5
1.4
1.7
0.5
1.5
0.2
0.9


YIL088C
0.9
2.1
2.1
1.3
1.6
2.2
1.7
0.8
1.0
1.7


YNL259C
1.6
3.5
1.1
1.2
1.1
3.9
3.8
1.5
1.6
2.1


YOR270C
0.7
0.5
2.0
0.8
0.8
1.8
1.0
0.6
0.4
0.9


YPL265W
0.7
0.4
2.3
1.1
1.0
2.3
8.9
2.3
0.2
1.2


YPR124W
0.2
0.4
0.3
1.4
2.0
2.0
2.9
2.7
0.2
1.5


YER119C
0.7
2.1
1.8
0.7
0.8
1.3
0.8
0.6
5.8
1.2


YFL055W
2.0
6.7
1.3
2.5
1.5
1.1
1.4
1.3
23.9
6.5


YLL055W
2.6
19.0
4.8
1.7
1.0
1.4
1.7
1.4
19.1
14.0


YHL036W
2.2
4.8
3.4
2.0
1.3
1.3
1.0
1.2
9.0
4.4


YHR048W
2.5
1.4
1.4
1.7
1.0
0.8
0.8
1.9
4.5
2.7


YKL221W
1.3
0.7
2.0
1.0
1.0
0.9
1.3
1.2
7.3
2.7


YLR092W
5.0
5.6
1.4
0.6
1.3
1.0
1.3
1.5
12.7
5.8


YML116W
4.1
1.3
1.5
1.4
1.2
0.9
1.4
2.2
1.4
3.1


YBR291C
2.0
0.9
1.0
1.5
0.9
1.1
0.9
2.2
0.9
1.0


YCL069W
0.9
4.5
0.9
0.8
0.9

1.4
1.3
1.2
6.9


YJR095W
1.2
20.5
1.9
6.7
1.2
1.5
2.0
0.9
0.5
6.3


YKL188C
1.3
0.7
1.9
2.4
1.0
0.8
1.1
0.7
2.5
2.8


YKL217W
1.8
2.4
1.0
2.1
1.1
1.2
1.6
1.1
0.9
4.1


YKR105C
0.8
0.9
0.9
1.5
1.0
1.2
1.0
1.3
1.0
5.2


YOL158C
0.7
4.0
2.4
0.9
1.2
2.0
1.6
0.7
1.7
6.1


YPL224C
1.0
2.2
1.3
2.5
0.6
1.3
2.2
1.3
3.2
4.2


YPR201W
33.2
0.9
1.1
1.0
1.2
1.9
0.8
0.9
8.3
5.6


YAL067C
2.7
12.1
1.5
1.4
0.7
1.2
0.8
1.1
7.6
2.9


YDL149W
0.8
2.0
1.2
1.6
1.5
1.0
0.7
1.2
3.2
2.0


YJL094C
1.0
1.7
1.3
2.0
1.4
1.3
1.7
0.8
5.4
2.9


YLL061W
3.6
2.8
9.2
0.4
0.8
0.8
0.9
1.4
3.7
5.5


YPL274W
0.8
4.2
3.8
0.8
0.6
1.1
0.7
0.9
4.1
3.6


YBR241C
0.9
9.3
2.6
0.9
0.9
1.5
1.4
0.7
29.8
2.2


YDL206W
0.9
1.7
1.8
1.4
1.1
5.7
2.0
1.1
1.6
1.5


YDR040C
0.7
1.4
3.7
0.8
1.0
1.7
0.7
0.8
2.0
1.2


YFR045W
1.1
1.6
1.1
1.1
1.0
1.0
0.6
1.0
2.2
1.0


YIL170W
1.1
1.0
2.5
2.2
0.9
8.8
0.5
1.2
5.7
3.2


YKL192C
1.1
1.0
3.7
1.1
1.1
1.8
1.1
0.9
3.5
1.6


YKL209C
1.0
1.0
1.3
0.8
1.2
3.3
0.9
1.4
2.4
1.6


YKR106W
1.3
0.8
2.1
1.4
1.2
1.6
0.9
1.3
10.5
7.4


YMR056C
1.1
1.3
1.7
1.0
1.1
0.9
1.4
1.2
1.8
1.1


YPL147W
1.0
0.8
2.3
1.2
1.2
1.1
1.0
0.9
2.4
2.4


YIL166C
1.9
12.5
2.1
1.2
1.0
1.9

1.3
2.5
2.9


YMR058W
0.3
5.1
2.1
0.3
0.8
2.6
1.8
0.8
0.2
1.4


YNL142W
0.7
2.4
2.5
0.8
1.3
0.9
1.1
0.8
0.9
0.6


YDL210W
1.2
2.2
2.7
1.1
0.9
1.3
0.8
1.1
1.2
1.4


YCL025C
1.1
4.6
2.5
1.7
0.9
0.9
0.7
0.7
0.3
0.3


YJL212C
0.8
3.2
3.1
0.5
1.2
1.1
0.7
0.7
1.1
1.3


YBR132C
0.9
1.9
2.4
1.8
0.8
1.2
1.1
0.8
0.8
1.1


YBL030C
1.0
0.9
4.5
0.9
0.7
1.1
0.9
0.8
0.4
0.9


YCR024C-A
0.8
0.9
3.2

0.9
1.2
0.8
0.8
0.2
0.7


YDR342C
2.8
1.1
12.2
5.7
1.6
1.1
0.8
1.2
0.2
2.2


YDR343C
1.2
1.0
20.6
4.6
1.3
1.3
0.7
1.2
0.3
2.1


YEL027W
1.2
0.6
3.4
1.1
1.0
1.1
0.8
0.9
0.9
1.1


YHR094C
0.7
1.2
5.3
1.6
1.1
1.6
0.8
1.2
0.3
1.2


YHR175W
0.8
2.0
2.4
1.5
0.9
1.0
1.6
0.9
0.6
2.0


YIL056W
1.1
0.9
6.2
1.4
1.2
1.0
0.6
0.7
1.2
1.6


YMR203W
0.8
0.7
3.0
1.4
0.6
1.1
0.8
0.7
0.7
1.2


YBL099W
0.8
0.9
3.1
1.4
1.0
0.9
0.9
0.8
0.9
0.7


YBR127C
0.8
0.7
2.2
1.1
1.4
1.1
0.9
1.1
0.6
1.3


YDR038C
0.6
1.3
3.1
0.9
0.9
1.8
0.7
0.9
1.4
0.9


YDR039C
0.6
1.6
3.2
0.9
1.3
1.1
0.8
0.6
1.8
1.0


YDR298C
1.3
1.2
2.6
1.3
1.3
1.2
1.0
1.2
1.0
1.6


YDR345C
0.8
0.9
5.6
2.6
1.3
1.2
1.1
1.2
0.2
1.1


YEL063C
0.7
0.8
2.4
1.3
1.2
1.3
0.7
0.6
0.8
1.7


YFL011W
1.2
0.7
3.7
3.3
1.3
1.0
0.8
0.8
0.3
1.6


YGR082W
1.0
0.9
2.2
1.0
0.9
1.1
0.9
0.8
0.6
0.9


YGR191W
0.8
0.7
1.6
1.5
0.8
1.1
0.7
0.7
0.1
0.7


YGR260W
0.6
0.7
3.4
0.8
0.8
0.9
0.9
0.5
0.3
0.4


YHR026W
0.9
1.0
1.9
1.0
1.1
1.3
0.9
1.6
1.1
0.9


YJR077C
1.1
1.1
2.0
1.6
0.9
0.9
0.7
0.8
0.4
0.7


YJR121W
0.9
1.1
3.3
1.0
0.8
1.5
1.0
0.7
0.8
1.3


YLR081W
1.3
0.8
2.8
3.6
1.0
0.9
0.7
0.9
0.1
2.2


YMR011W
1.3
1.0
9.4
5.5
0.9
0.6
0.8
1.1
0.0
0.7


YOL156W
1.1
0.7
2.5
1.1
1.2
1.2
1.0
1.0
2.3
2.1


YPL036W
0.5
0.8
2.8
0.9
1.3
0.7
0.3
0.5
0.1
0.3


YGR096W
1.5
1.0
1.1
4.6
1.2
1.7
0.9
1.0
0.8
0.8


YIL006W
1.0
1.1
1.4
2.9
0.8
0.3
0.8
0.6
0.9
1.1


YKL016C
1.5
1.3
0.7
1.7
1.5
0.8
1.5
1.6
1.3
1.8


YKR067W
0.8
2.6
1.5
2.5
1.3
1.8
2.0
0.8
1.6
2.3


YMR162C
0.8
1.1
1.1
2.0
0.9
1.0
0.8
0.8
0.7
1.0


YOR348C
1.1
0.7
1.2
2.0
0.9
0.7
0.8
0.8
0.5
0.4


YPR192W
0.9
1.1
0.9
5.0
1.2
0.9
0.9
0.6
0.7
1.3


YPR194C
2.2
1.4
0.5
2.9
1.3
1.5
0.7
1.0
0.5
0.6


YDR086C
1.3
1.0
1.2
1.4
1.0
0.8
2.0
1.9
0.6
0.8


YGR224W
0.9
1.2
1.2
1.2
1.4
0.8
0.4
0.6
0.9
0.9


YDR387C
0.8
0.9
1.2
2.2
0.9
1.2
1.3
0.7
1.4
2.0


YFL050C
0.7
1.0
1.1
2.2
1.0
0.9
0.8
0.9
0.5
1.6


YBR298C
1.1
1.0
1.6
2.3
1.4
0.4
1.7
0.5
0.3
1.1


YLR295C
1.4
1.1
1.1
1.7
2.2
1.1
1.1
1.2
1.4
1.2


YNR072W
1.1
1.5
0.5
0.7
1.0
0.9
1.5
0.9
0.7
1.8


YOR316C
0.7
2.5
1.5
1.5
1.0
0.9
1.4
0.8
1.6
2.0


YOR328W
1.0
1.0

1.0
1.0
2.9


YPL134C
1.5
1.0
1.6
1.6
1.4
1.2
1.2
1.3
0.6
0.8











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YBR008C
9.4
0.8
2.0
4.1
0.8
3.1
2.0
1.2
0.37


YBR296C
1.5
1.6
2.0
2.3
1.7
0.3
3.8
4.0
0.54


YDR406W
1.4
3.9
7.7
0.5
0.8
5.5
2.7
5.6
0.53


YOR153W
1.0
4.0
11.8
0.3
3.6
1.6
2.5
3.1
1.91


YGR281W
0.7
2.4
12.9
0.9
2.1
1.1
2.8
3.1
1.04


YHL047C
1.0
2.6
3.8
0.5
1.1
2.3
1.2
1.2
0.74


YBR294W
1.2
1.0
3.1
1.3
1.0
0.9
1.0
0.9
0.18


YGL006W
0.8
0.9
4.5
0.9
1.1
1.7
2.4
4.1
1.37


YGR197C
1.1
1.2
2.4
1.5
1.0
1.5
1.7
1.9
0.37


YJL034W
1.3
1.6
6.1
0.6
7.9
0.6
1.1
1.0
4.58


YNL055C
1.9
1.7
2.4
0.9
1.1
2.6
1.2
1.7
4.10


YBR052C
1.7
1.3
2.1
1.5
0.7
3.1
1.8
3.1
2.77


YBR207W
1.1
0.9
2.2
0.9
1.4
1.4
1.2
1.4
1.39


YBR293W
1.1
1.0
3.0
1.4
3.1
1.6
1.0
0.9
0.94


YDL198C
2.5
1.2
2.0
1.7
1.2
1.4
1.5
1.1
1.19


YDL245C
1.5
1.0
2.0
1.2
1.8
1.5
1.0
1.1
0.28


YDR497C
0.7
0.9
2.7
0.6
10.1

1.6
1.8
1.45


YER053C
2.4
.1.7
4.1
1.3
1.1
2.8
1.2
2.3
1.83


YFL041W
0.9
1.1
1.8
1.0
0.9
1.4
1.1
0.9
0.89


YGR055W
1.5
0.9
1.9
1.2
2.1
0.6
0.7
0.7
1.42


YJL219W
2.3
1.1
4.0
1.1
2.6
1.4
1.6
1.2
0.91


YJR106W
1.6
0.9
3.5
0.9
1.2
1.9
1.2
1.3
0.29


YKL146W
0.9
1.1
2.7
1.0
1.5
1.3
1.0
0.9
0.42


YLL028W
0.7
1.3
4.1
0.7
3.1
0.6
1.2
1.2
1.02


YLR348C
1.3
0.9
1.9
1.0
2.4
1.1
1.1
1.0
0.64


YOL119C
3.4
0.9
1.6
2.4
4.7
2.8
1.4
1.0
0.37


YOL163W
1.6
1.0
2.4
1.2
1.0
1.4
0.8
0.8
0.30


YOR035C
1.0
1.1
2.5
0.9
3.8
1.8
1.6
2.1
0.52


YOR130C
0.6
0.9
2.1
1.3
1.0
0.8
1.5
1.1
0.51


YOR273C
1.5
0.8
2.6
0.5
0.8
0.6
3.2
3.1
1.20


YOR332W
1.5
1.0
2.2
1.1
1.2
1.2
1.3
1.7
3.58


YCR098C
1.3
1.3
1.4
1.1
11.0
0.8
1.7
1.6
0.22


YGR138C
0.7
0.6
0.6
0.9
4.5
0.7
0.7
0.7
1.24


YBR295W
1.1
0.9
1.8
1.1
4.8
1.4
1.3
1.2
0.27


YGL255W
0.5
0.7
0.2
1.0
2.6
0.5
0.6
0.5
1.36


YHL035C
0.9
1.4
1.1
0.8
3.1
2.4
1.1
1.2
0.77


YIL022W
1.0
0.9
1.2
0.6
2.9
1.1
0.8
0.7
0.52


YLR378C
1.0
1.2
1.6
0.4
5.9
0.4
0.9
0.7
1.23


YCL038C
2.0
1.3
1.9
1.3
2.0
1.8
1.4
1.5
1.04


YFL054C
1.7
1.2
2.3
0.9
1.4
1.3
1.7
1.4
1.06


YHL040C
1.7
2.0
2.0
1.1
3.4
1.0
1.4
1.0
0.69


YKR039W
1.9
1.5
1.3
1.2
1.7
1.9
0.9
1.1
0.40


YPL271W
1.7
0.8
1.2
1.3
0.8
1.4
1.2
1.3
1.34


YBR068C
0.8
0.8
2.2
1.8
1.6
5.5
1.1
1.3
1.99


YCR037C
0.8
0.7
1.3
0.8
1.0
1.1
1.4
0.9
0.74


YDL128W
1.2
0.9
1.6
0.7
1.1
1.0
0.9
1.0
2.80


YDR270W
1.0
1.0
1.8
1.0
1.4
1.1
0.9
0.7
0.38


YEL065W
0.6
1.7
0.8
0.4
2.2
2.6
0.7
0.6
2.10


YGL008C
0.7
2.4
1.9
1.2
1.0
2.1
1.1
1.0
4.08


YGL104C
1.8
1.1
2.0
1.0
0.9
1.7
1.3
1.3
0.58


YGL167C
0.8
1.1
1.5
0.8
1.3
1.3
1.4
1.4
1.41


YGR065C
1.1
0.5
0.8
1.3
1.2
1.1
0.7
0.7
0.68


YHR092C
1.5
1.0
0.5
1.6
0.2
1.2
0.9
1.3
6.09


YIL088C
1.8
0.9
1.5
1.2
1.2
1.8
1.2
1.4
1.89


YNL259C
1.6
0.7
1.1
1.4
0.7
1.7
2.6
2.4
1.22


YOR270C
1.5
0.7
1.3
0.7
1.1
0.8
0.9
0.9
3.49


YPL265W
1.8
0.9
1.1
1.1
1.2
2.0
0.5
0.4
1.42


YPR124W
2.0
0.8
0.6
0.4
1.1
2.4
1.0
1.3
2.57


YER119C
2.2
0.7
1.6
1.0
2.3
0.8
1.0
0.9
0.32


YFL055W
2.7
0.9
1.3
1.5
0.7
1.4
1.4
1.0
0.23


YLL055W
3.6
0.7
1.5
1.3
0.7
2.8
1.1
1.3
0.47


YHL036W
2.3
1.2
1.5
1.2
0.9
1.1
1.0
1.0
0.60


YHR048W
2.0
0.9
1.1
1.7
0.9
1.4
0.7
0.9
0.26


YKL221W
1.9
0.7
1.6
1.4
1.1
1.3
0.8
0.9
0.27


YLR092W
3.1
1.0
1.8
1.4
0.9
1.2
1.0
1.1
0.24


YML116W
4.3
0.5
0.8
2.0
1.9
1.0
1.0
1.0
0.94


YBR291C
1.1
0.9
1.0
1.7
0.5
1.5
0.9
1.3
1.19


YCL069W
1.0
0.9
0.8
1.3
1.4
0.9
1.0
1.0
0.25


YJR095W
0.6
0.7
0.8
1.3
0.8
0.8
1.3
0.9
0.23


YKL188C
1.1
1.2
1.2
2.1
1.4
2.7
1.1
1.5
0.27


YKL217W
1.6
0.8
1.2
1.2
2.2
3.0
1.7
3.3
0.29


YKR105C
0.0
0.8
2.5
1.2
1.5
0.7
0.8
1.0
0.26


YOL158C
0.7
0.9
1.4
1.0
0.9
1.2
1.4
1.7
1.30


YPL224C
0.8
1.1
1.3
1.4
1.0
2.5
1.3
1.9
0.64


YPR201W
2.2
0.7
1.1
1.8
0.8
0.9
0.8
0.9
0.29


YAL067C
1.2
1.0
1.1
1.3
2.4
1.6
1.0
1.0
0.33


YDL149W
1.2
0.7
1.5
1.2
1.8
1.4
0.8
1.0
0.33


YJL094C
1.1
1.2
2.6
1.0
1.0
1.8
2.1
2.0
0.84


YLL061W
1.7
0.7
0.9
1.3
1.4
1.0
0.6
0.7
0.33


YPL274W
2.0
0.5
0.6
0.9
1.5
1.1
0.7
0.6
0.41


YBR241C
1.4
1.4
1.4
0.9
1.6
0.7
1.0
1.2
1.25


YDL206W
0.6
1.0
1.3
1.0
1.1
3.1
1.0
1.1
0.35


YDR040C
0.8
0.9
1.8
0.9
0.8
1.4
1.4
1.6
1.25


YFR045W
1.4
1.0
1.1
1.0
1.1
0.6
0.9
0.8
0.84


YIL170W
1.7
0.7
1.9
1.1
2.3
1.8
1.6
1.5
0.48


YKL192C
1.1
1.2
1.7
1.5
1.2
2.1
1.0
0.8
1.57


YKL209C
0.8
0.9
1.4
1.1
1.0
1.1
1.1
1.0
0.30


YKR106W
1.8
0.8
1.4
1.7

2.8
0.9
0.8
0.16


YMR056C
1.6
0.9
0.9
1.1
0.7
2.4
1.0
1.1
0.72


YPL147W
1.3
0.9
1.5
1.0
2.4
2.5
1.5
3.6
0.33


YIL166C
1.8
0.9
1.5
1.1
1.3
0.7
1.2
0.9
0.26


YMR058W
0.8
0.8
0.4
0.3
0.5
0.4
0.6
0.5
1.66


YNL142W
0.9
1.2
0.9
0.8
0.3
1.0
1.0
0.9
0.44


YDL210W
0.6
0.8
1.2
1.1
1.9
0.9
1.1
0.9
0.20


YCL025C
1.0
1.1
0.5
0.7
0.8
0.6
0.6
0.6
1.98


YJL212C
0.9
0.4
1.0
0.8
0.3
0.5
0.6
0.5
0.59


YBR132C
1.9
1.0
1.4
1.1
1.5
1.3
1.1
1.3
0.43


YBL030C
1.1
0.9
0.5
0.8
1.8
1.0
1.0
1.1
3.12


YCR024C-A
1.5
1.0
0.5
0.8
1.3
1.5
0.9
1.4
4.02


YDR342C
2.9
1.0
0.6
0.9
0.5
2.4
1.0
2.2
5.23


YDR343C
2.3
1.0
0.8
0.8
0.5
2.8
1.1
2.3
5.81


YEL027W
0.9
0.9
0.7
1.4
1.5
1.6
1.0
1.4
4.75


YHR094C
0.6
0.9
0.7
0.6
2.7
0.9
1.4
1.4
4.82


YHR175W
1.1
1.4
1.2
0.7
1.3
2.3
1.3
1.2
1.01


YIL056W
0.7
1.0
1.5
1.0
0.5
0.9
1.5
1.2
0.71


YMR203W
2.3
0.7
1.1
0.7
1.2
0.9
0.8
0.7
1.62


YBL099W
2.1
1.0
0.9
0.6
1.0
0.9
0.7
1.2
3.49


YBR127C
1.1
0.9
0.9
0.6
1.3
1.4
0.8
1.0
4.59


YDR038C
0.9
0.7
2.0
0.8
0.8
1.4
1.3
1.5
1.32


YDR039C
0.9
0.8
1.8
0.9
1.2
1.4
1.1
1.6
1.39


YDR298C
1.2
1.1
1.2
1.5
0.8
2.0
1.1
1.6
2.69


YDR345C
1.5
1.4
1.2
0.8
0.8
1.0
1.3
1.8
5.65


YEL063C
0.8
1.1
1.1
0.8
1.3
1.0
0.7
0.7
1.12


YFL011W
2.1
0.9
0.8
0.8
1.7
1.2
0.8
1.0
1.25


YGR082W
1.3
0.8
0.5
0.9
1.2
1.3
0.9
0.8
1.47


YGR191W
1.6
0.7
1.0
0.7
1.5
0.7
0.8
0.8
1.58


YGR260W
1.3
0.6
0.5
0.7
1.8
1.0
0.9
0.9
1.71


YHR026W
1.4
0.7
0.7
1.3
2.4
1.2
0.9
1.1
3.40


YJR077C
1.6
1.0
0.9
0.7
1.5
0.7
1.0
0.8
1.79


YJR121W
0.9
0.8
1.0
0.7
0.9
1.2
1.1
1.4
3.99


YLR081W
2.6
1.0
0.6
1.0
0.7
1.2
0.7
0.9
1.46


YMR011W
1.5
0.8
0.4
0.6
0.6
1.2
1.3
1.6
4.95


YOL156W
1.1
0.9
1.7
0.9
1.9
0.9
0.9
0.9
0.53


YPL036W
0.8
0.5
0.3
0.6
1.0
0.7
0.4
0.5
3.66


YGR096W
0.8
0.8
1.1
1.2
0.9
0.8
0.8
1.0
0.49


YIL006W
1.0
0.9
0.8
1.0
1.5
1.7
0.8
0.9
0.28


YKL016C
1.3
1.0
1.3
1.6
0.7
1.8
1.0
1.7
2.08


YKR067W
1.3
1.0
1.3
1.3
1.3
2.0
0.8
1.0
0.58


YMR162C
1.7
0.7
0.9
1.0
1.0
0.8
0.8
1.1
0.32


YOR348C
1.1
0.7
1.1
1.2
1.6
1.7
0.9
0.9
0.18


YPR192W
0.7
0.5
1.1
0.7
1.7
2.6
1.6
0.9
0.28


YPR194C
0.7
0.7
1.0
1.0
0.4
0.8
1.0
0.9
0.27


YDR086C
1.1
0.7
0.7
1.5
2.1
1.3
1.4
1.9
2.60


YGR224W
0.8
0.6
0.8
0.9
1.1
1.0
2.8
1.3
0.27


YDR387C
2.0
0.9
1.3
0.9
1.4
2.7
1.2
1.1
0.86


YFL050C
1.2
0.9
1.2
1.0
1.4
2.3
0.8
1.0
0.36


YBR298C
1.5
1.1
0.8
0.9
0.2
2.1
0.9
0.8
0.88


YLR295C
1.3
0.5
0.8
1.2
0.5
2.4
0.9
1.5
1.07


YNR072W
1.4
1.0
1.5
1.0
1.8
2.1
1.3
1.0
0.26


YOR316C
2.4
1.1
1.6
1.0
1.5
2.2
0.8
1.0
0.93


YOR328W
1.1
1.8

0.8
3.3
2.1


0.19


YPL134C
1.7
0.8
1.0
1.4
1.1
3.3
1.3
1.3
0.70










[0037]

7





TABLE 6








Stress protein genes
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YBR072W
18.5
17.4
18.4
10.5
1.2
32.2
6.6
2.1
29.4
43.4


YFL014W
3.4
5.1
5.7
11.0
1.0
9.3
5.5
3.4
13.1
5.8


YLL060C
12.5
4.2
2.3
2.6
0.9
1.4
2.0
5.8
13.0
23.2


YAL005C
0.6
1.6
7.0
0.9
1.2
1.6
1.2
0.9
3.9
1.8


YBL075C
1.3
4.3
3.1
1.6
1.1
0.8
1.3
0.8
60.3
6.7


YBR169C
1.0
2.1
3.9
1.9
0.8
4.9
2.5
0.9
7.0
4.3


YCL035C
2.0
2.3
1.5
1.7
1.5
5.1
2.7
1.4
1.9
2.3


YCR060W

0.7
0.9

0.8
3.3
2.4
1.2
0.7
1.1


YDR155C
1.1
1.5
3.2
1.8
0.8
1.5
1.2
1.4
1.3
1.3


YDR258C
1.6
2.3
2.8
1.4
1.3
2.4
3.9
1.9
4.9
13.3


YER103W
0.7
2.1
5.2
2.1
1.1
1.7
1.0
0.9
20.3
9.0


YKL210W
0.5
1.7
2.7
0.7
0.8
1.4
1.0
0.9
3.5
2.9


YLL024C
0.5
1.6
5.3
0.8
0.7
1.0
1.1
0.7
2.8
2.4


YLL026W
1.8
2.9
7.7
1.7
0.9
1.9
2.9
1.4
11.4
6.6


YNL160W
2.1
3.7
10.6
2.0
1.3
5.8
2.4
1.2
3.5
2.7


YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4


YOR027W
0.7
2.4
4.4
0.8
1.0
1.6
1.3
0.9
3.5
4.0


YPL240C
0.7
1.4
2.4
0.9
1.3
1.2
1.4
1.2
3.5
2.6


YDR293C
0.9
0.9
1.2
1.4
0.6
0.9
0.9
0.6
1.2
1.2


YDR436W
0.9
0.9
1.1
1.4
0.7
1.1
1.2
0.9
3.5
1.1


YDR519W
1.3
3.2
1.7
1.6
0.7
1.3
1.9
1.4
0.5
1.2


YEL030W
0.7
0.9
1.9
1.1
0.4
0.6
0.9
0.7
2.3
2.5


YER125W
0.6
1.1
1.5
0.9
1.4
0.7
0.8
0.7
0.6
1.2


YFL016C
0.8
1.0
1.6
0.9
1.3
1.3
1.4
0.7
6.4
2.9


YFR052W
1.1
1.6
1.3
1.5
1.4
3.2
2.2
1.5
3.7
3.0


YHR057C
1.1
1.2
0.7
0.9
1.3
1.3
1.3
1.0
2.6
1.2


YIR037W
1.4
2.2
2.0
2.3
0.6
2.7
1.8
1.3
6.2
3.8


YIR038C
1.3
3.5
4.6
2.0
0.7
2.5
2.0
1.3
4.6
4.5


YJR045C
0.5
1.9
3.9

0.5
1.2
1.0
0.8
3.2
3.0


YLL039C
1.1
1.0
1.7
1.2
0.9
1.5
1.1
1.1
3.4
1.5


YLR259C
0.7
1.0
3.1
1.6
1.1
0.9
1.8
0.8
1.8
2.6


YML070W
0.9
1.7
2.5
1.9
1.4
2.2
3.1
1.3
4.5
3.9


YPL106C
0.6
1.7
2.4
1.1
1.2
1.6
1.1
1.2
4.9
1.8


YPR026W
0.9
1.2
5.0
1.3
0.8

1.3
1.0
0.9
3.1


YDR077W
1.2
1.0
3.5
2.1
0.8
1.0
0.7
0.8
0.7
0.7


YKL163W
1.1
1.4
3.4
1.9
0.6
1.1
0.9
0.8
0.7
1.6


YLR109W
0.8
2.9
6.0
0.9
1.3
2.1
2.6
0.9
2.4
2.7


YOR208W
1.3
1.0
1.2
2.9
1.4
1.8
1.1
1.0
1.5
2.0


YDR098C
0.8
1.4
1.0
0.8
1.5
1.1
.1.5
1.2
3.7
1.5


YHR030C
2.1
0.8
0.6
2.9
1.8
0.9
1.8
1.5
0.6
2.5


YJL159W
1.0
1.3
2.8
1.1
1.0
1.8
0.9
0.8
0.5
1.2


YMR173W
1.5
3.6
3.0
0.9
1.1
5.0
2.4
2.3
2.7
8.2


YCR021C
5.2
1.4
4.2
8.6
0.9
2.2
0.9
0.8
2.2
1.0


YDL022W
0.9
2.6
6.9
1.5
0.7
2.1
1.5
0.8
1.2
1.8


YDR033W
1.1
1.3
4.6
1.5
1.1
6.7
0.8
1.0
0.3
1.0


YFL020C
1.0
1.1
1.9
1.2
1.1
2.0
1.4
0.7
1.3
1.4


YGL073W
1.0
2.1
0.9
1.0
1.7
1.9
1.3
0.8
1.9
2.4


YIL033C
0.8
1.3
3.3
1.3
0.7
2.0
1.1
0.7
2.4
1.3


YMR021C
1.0
0.7
0.9
1.1
1.6
2.2
2.5
1.3
0.6
1.3


YBR126C
0.8
1.9
5.6
1.2
0.7
2.9
2.3
0.6
1.7


YBR067C
1.6
2.5
2.8
0.9
1.1
1.1
1.1
1.1
1.7
1.0


YDR513W
2.2
2.5
2.3
2.6
0.9
2.1
1.6
1.6
4.6
3.1


YGR088W
1.3
1.2
7.7
2.4
1.0
1.3
0.8
0.8
1.5
3.2


YHR104W
1.0
4.1
15.7
1.9
1.1
1.2
1.5
1.1
4.8
2.3


YKL161C
4.2
0.8
0.9
2.2
1.4
2.0
2.0
1.9
1.4
1.7


YPL223C
4.8
20.0
1.2
5.1
0.9
1.5
1.1
1.2
29.4
16.5


YBR054W
1.9
1.8
5.4
1.7
0.8
1.1
0.6
2.1
0.4
1.2


YAL015C
1.2
1.1
1.7
1.9
1.1
0.7
1.2
1.1
4.0
2.7


YDL025C
1.7
5.0
3.5
1.5
0.6
0.6
1.0
1.1
3.6
4.5


YML007W
0.9
0.8
0.9
1.3
1.0
0.5
1.1
1.9
2.1
2.5


YER042W
3.0
2.2
3.1
1.0
1.1
1.6
1.1
1.7
6.8
2.1


YOL064C
1.4
2.1
1.1
0.6
0.9
1.4
1.2
1.0
8.7
2.7


YGL181W
0.9
0.9
1.2
1.1
1.1
1.9
1.3
1.2
2.7
2.3


YJL128C
0.8
1.4
0.4
0.8
1.2
1.3
1.8
0.9
2.0
1.7


YJL165C
1.0
0.8
1.3
1.6
1.1
0.5
0.8
0.7
2.8
1.0


YJR090C
0.8
1.0
0.6
0.8
1.2
1.2
0.8
0.8
1.9
1.2


YMR186W
0.6
1.4
2.0
0.9
1.3
1.3
1.2
0.8
2.6
1.3


YNL064C
0.9
1.8
1.8
1.1
0.9
0.8
0.6
1.4
2.4
1.8


YOR008C
0.7
0.8
1.4
1.1
1.4
1.1
0.8
0.8
1.9
1.0


YPL194W
0.9
1.4
0.4
1.1
1.3
1.1
1.5
1.3
9.6
3.1


YBL093C
1.0
2.0
0.4
1.4
1.0
0.8
1.3
1.6
0.7
1.1


YKR053C
0.9
2.0
1.0
1.2
1.0
1.1
1.7
0.9
0.8
1.8


YJL158C
0.9
0.6
2.8
1.5
1.4
0.5
0.4
0.7
0.2
0.5


YER057C
1.2
2.0
3.0
1.8
0.8
1.6
1.4
1.0
0.6
1.4


YHL046C
1.1
1.7
2.1
1.3
0.9
0.8
1.3
1.0
1.0
2.1


YIL011W
0.7
0.5
3.9
0.6
1.1
0.7
0.6
0.7
0.0
0.5


YKL164C
0.6
1.1
2.5
0.9
1.1
1.4
0.8
0.8
0.4
0.7


YNR076W
1.3
1.3
2.5
1.0
1.2
1.2
1.2
1.0
1.3
2.5


YOL161C
1.2
1.1
2.4
1.4
0.9
1.0
0.9
0.8
0.7
2.0


YOR009W
0.9
0.8
3.2
0.7
0.8
0.9
0.6
0.7
0.4
0.5


YOR010C
0.7
0.7
3.2
0.6
1.2
0.5
0.4
0.5
0.6
0.7


YPL059W
1.2
0.9
2.6
1.3
1.2
1.3
0.7
1.4
2.0
1.3


YBR044C
0.8
1.4
0.7
1.9
1.4
1.0
1.5
1.1
0.8
1.2


YEL039C
1.1
0.7
1.3
5.1
0.9
1.5
0.6
1.1
1.2
1.2


YGL115W
0.9
0.6
1.2
2.0
1.2
1.2
1.4
1.0
1.2
1.2


YLR006C
0.7
0.7
0.9
6.2
1.6
0.9
1.1
0.9
1.1
1.1


YPR005C
1.3
0.8
1.5
3.8
1.0
0.8
1.2
1.2
2.8
2.0


YHL028W
0.7
0.8
1.4
0.5
1.1
1.8
2.1
0.4
0.2
0.4


YCR083W
1.1
2.8
1.5
1.8
1.6
2.4
1.8
1.5
1.8
1.8


YPL140C
0.9
1.3
0.9
1.0
0.8
0.3
1.4
1.1
0.9
0.9











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YBR072W
6.3
16.3
38.5
5.8
4.9
23.1
1.8
2.2
0.59


YFL014W
5.0
4.3
15.2
7.3
6.3
14.2
1.5
8.8
2.14


YLL060C
14.1
1.1
1.8
10.6
1.5
3.6
1.9
2.3
0.57


YAL005C
1.0
1.2
5.0
0.4
1.6
0.7
0.8
0.5
5.23


YBL075C
1.6
1.1
8.0
1.1
2.6
2.2
1.2
0.7
1.17


YBR169C
2.2
1.7
7.2
1.1
1.6
2.4
1.3
1.6
1.10


YCL035C
2.1
1.5
2.8
2.5
1.9
5.5
2.6
4.2
1.74


YCR060W
1.2
1.7
8.6
1.7

3.3
1.2
1.7
1.04


YDR155C
3.8
1.4
3.3
1.0
2.5
1.6
1.2
2.5
4.99


YDR258C
1.7
1.8
5.2
1.5
0.6
1.0
1.3
1.3
0.87


YER103W
1.8
1.9
9.0
0.9
3.2
1.2
1.4
0.6
2.10


YKL210W
1.4
1.3
2.9
0.8
1.0
0.9
0.7
1.1
2.29


YLL024C
1.6
1.0
4.8
0.4
1.3
0.5
0.5
0.6
5.12


YLL026W
1.7
1.9
8.1
0.8
0.9
1.6
1.7
2.5
2.56


YNL160W
5.4
1.4
6.0
1.3
0.7
4.0
1.0
1.0
1.77


YNL241C
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68


YOR027W
1.3
1.3
5.1
0.8
1.4
0.6
0.9
0.8
1.52


YPL240C
1.0
0.8
2.9
0.7
1.2
0.7
0.8
1.0
4.83


YDR293C
1.1
0.9
2.3
0.8
1.7
1.6
1.4
1.3
1.12


YDR436W
2.0
0.9
2.7
1.2
0.8
1.4
0.9
1.2
0.53


YDR519W
1.2
1.7
2.5
1.3
2.0
1.5
1.8
2.4
2.01


YEL030W
1.7
0.9
2.7
0.7
0.8
0.8
0.9
0.6
1.28


YER125W
1.0
0.7
1.9
0.7
0.8
1.0
1.0
1.0
1.48


YFL016C
1.2
1.0
2.8
0.8
0.8
0.6
1.2
0.9
1.25


YFR052W
0.9
1.8
3.8
3.3
1.4
2.7
1.2
1.9
1.62


YHR057C
1.6
1.1
1.9
1.9
1.2
2.2
1.6
1.3
1.07


YIR037W
3.0
1.3
2.4
2.3
1.0
4.0
1.7
2.9
1.97


YIR038C
3.4
1.1
2.5
2.5
1.2
6.0
2.8
2.0
1.11


YJR045C
1.4
1.0
2.3
0.5
2.3
0.8
0.7
0.9
3.78


YLL039C
1.1
1.0
2.2
1.4
3.0
1.1
1.6
2.1
3.60


YLR259C
3.0
0.7
2.5
0.8
2.1
1.3
0.8
1.0
2.09


YML070W
1.5
1.3
3.3
1.3
0.9
2.6
1.2
1.3
1.03


YPL106C
1.3
1.1
3.1
0.9
1.1
0.5
0.5
0.5
3.34


YPR026W
1.6
1.2
2.3
1.5
3.1
2.5
0.9
1.3
0.26


YDR077W
6.8
0.8
1.0
0.3
6.1
1.0
1.4
1.1
4.77


YKL163W
1.3
0.9
1.5
0.5
16.8
3.0
0.8
1.0
2.01


YLR109W
1.5
1.6
3.2
2.3
3.9
1.8
1.1
1.2
3.86


YOR208W
1.2
1.2
1.5
1.3
4.4
1.9
1.6
1.6
0.56


YDR098C
1.4
1.3
1.2
1.5
2.2
0.8
1.0
1.2
1.59


YHR030C
1.5
0.7
1.0
1.1
3.4
1.4
2.0
1.8
1.05


YJL159W
1.2
1.0
1.7
0.6
5.3
1.0
1.4
0.9
2.45


YMR173W
3.2
1.4
2.0
2.3
2.5
1.2
1.9
1.8
1.37


YCR021C
0.6
0.5
0.9
1.6
0.5
0.6
0.7
0.8
1.36


YDL022W
2.8
1.2
1.5
0.8
0.9
1.1
1.0
1.4
1.79


YDR033W
0.7
1.0
0.7
1.0
0.8
1.0
0.7
1.0
5.78


YFL020C
1.2
1.3
1.4
1.0
1.4
0.9
1.5
0.9
0.70


YGL073W
0.8
0.8
1.5
1.2
0.9
1.1
2.5
1.2
0.66


YIL033C
1.8
1.1
2.5
0.7
1.0
2.0
1.0
1.2
1.18


YMR021C
0.9
0.8
1.4
1.3
1.0
2.0
3.3
3.4
1.14


YBR126C
1.1
1.3
2.1
0.7
1.0
1.7
1.5
1.3
1.96


YBR067C
3.1
1.0
0.9
0.7
3.3
2.5
0.5
0.4
1.76


YDR513W
2.0
0.9
1.8
2.0
1.3
3.8
1.3
3.2
3.10


YGR088W
3.9
1.1
1.2
1.3
0.7
5.6
0.9
2.0
0.75


YHR104W
2.6
1.0
1.2
1.5
1.6
1.3
1.9
1.9
1.57


YKL161C
3.1
0.9
1.3
1.4
1.3
1.1
1.4
1.9
0.45


YPL223C
1.8
0.9
2.3
2.5
1.5
19.0
1.0
1.3
0.31


YBR054W
1.8
0.7
1.5
1.0
0.6
0.4
0.7
0.7
3.02


YAL015C
1.4
1.0
1.2
1.6
0.7
2.0
1.1
1.2
0.61


YDL025C
1.5
0.9
1.2
1.7
1.0
1.7
1.0
1.4
0.56


YML007W
1.3
1.1
1.7
1.2
1.0
1.4
1.0
1.4
1.54


YER042W
1.8
1.1
1.4
5.2
1.0
1.9
0.7
1.1
1.80


YOL064C
1.0
0.9
2.0
0.9
1.0
1.7
1.2
1.3
1.32


YGL181W
1.2
1.0
2.8
1.0
1.5
1.3
1.0
1.3
0.98


YJL128C
0.6
1.0
1.7
0.8
1.2
0.9
1.0
1.0
0.42


YJL165C
1.7
0.9
1.5
0.9
1.0
1.5
1.3
1.8
0.87


YJR090C
0.4
0.8
2.2
1.0
1.6
0.8
1.1
1.0
0.60


YMR186W
1.1
1.0
2.4
0.6
1.3
0.6
0.7
1.1
6.64


YNL064C
0.9
0.8
1.1
0.8
0.7
0.3
0.7
0.7
3.79


YOR008C
1.0
0.7
0.9
0.9
0.9
1.2
0.8
1.3
1.75


YPL194W
0.9
0.9
1.4
1.1
1.4
0.9
1.0
0.8
0.22


YBL093C
1.3
1.1
2.1
1.0
0.5
0.9
1.4
1.3
1.47


YKR053C
0.5
0.7
0.7
1.3
0.3
0.9
2.8
2.4
0.35


YJL158C
1.9
1.1
0.4
0.5
1.7
0.6
1.4
1.4
3.48


YER057C
1.8
1.5
1.0
1.4
1.7
2.8
1.1
1.8
2.03


YHL046C
0.4
1.1
1.4
1.4
1.0
1.4
0.9
0.9
0.55


YIL011W
2.5
0.6
0.5
0.5
0.9
1.0
0.8
0.8
0.57


YKL164C
1.0
0.8
0.9
0.3
1.2
1.1
0.8
0.8
2.75


YNR076W
1.4
0.7
0.9
0.8
1.1
0.8
1.5
0.8
0.42


YOL161C
1.5
1.3
1.2
0.9
1.1
1.6
1.1
1.0
0.89


YOR009W
1.4
0.4
0.4
0.7
0.6
0.8
0.9
0.8
0.36


YOR010C
1.2
0.5
0.5
0.4
0.6
1.1
1.4
0.6
0.61


YPL059W
1.6
0.8
0.7
1.3
1.0
2.1
1.8
1.3
1.35


YBR044C
1.1
0.8
1.2
0.9
0.9
1.4
0.9
1.3
0.57


YEL039C
1.7
0.6
0.5
1.4
0.4
3.5
0.7
1.1
1.59


YGL115W
1.0
0.9
0.7
1.2
0.7
1.7
0.8
1.2
2.46


YLR006C
1.5
0.7
0.8
1.0
0.9
0.8
1.6
1.0
0.40


YPR005C
0.4
0.6
0.7
1.3
2.7
0.8
1.0
1.1
0.24


YHL028W
0.7
1.5
2.1
1.3
0.6
2.6
1.6
2.5
0.62


YCR083W
1.8
1.1
1.8
2.4
1.0
3.1
1.3
1.3
0.98


YPL140C
0.8
0.8
0.9
1.1
0.7
1.8
0.9
1.4
0.46










[0038]

8





TABLE 7








Metabolism protein genes
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YCR107W
12.0
2.6
1.8
1.6
0.7
1.5
1.5
15.6
196.6
34.0


YDL243C
14.4
2.7
2.4
1.0
1.1
2.2
1.6
11.8
64.2
29.6


YFL014W
3.4
7.2
5.7
11.0
1.0
9.3
5.5
3.4
13.1
5.8


YFL056C
19.0
2.3
2.3
1.5
0.9
0.6
1.4
18.5
162.3
31.3


YFL057C
20.9
5.8
1.5
1.8
0.9
1.2
1.8
18.0
51.8
46.1


YJR155W
10.6
3.7
1.4
2.5
0.7
1.4
1.7
10.6
38.2
18.8


YNL331C
8.6
3.6
1.3
1.0
1.6
1.8
1.9
13.1
42.6
36.3


YNL332W
1.1
1.5
1.1
2.0
1.6
1.1
2.1
1.5
3.3
2.1


YOL165C
10.1
4.5
1.8
0.9
0.9
1.7
1.4
17.8
46.9
23.3


YPR167C
5.3
5.8
1.9
0.8
1.4
2.6
1.2
5.5
76.6
9.0


YBR256C
3.0
1.4
0.6
1.3
1.6
2.0
2.1
2.3
18.1
6.8


YBR296C
7.0
11.2
2.2
2.5
1.4
1.4
0.2
1.1
0.4
1.8


YDL021W
4.8
1.7
2.4
3.7
1.7
6.5
5.9
2.7
2.5
7.4


YFL061W
1.5
1.4
2.1
3.0
1.0
0.5
1.2
1.2
3.2
9.9


YGR043C
2.5
4.7
3.2
7.9
0.9
16.3
6.5
2.6
10.9
8.4


YHR112C
1.8
3.1
0.7
1.4
1.3
2.9
3.4
1.7
10.5
4.4


YIR030C
1.4
1.0
0.9
1.3
0.9
0.5
1.2
1.4
5.4
2.1


YJR010W
9.1
7.3
4.9
0.8
1.1
2.5
1.4
3.1
30.0
11.1


YKL001C
6.8
21.4
5.6
1.8
0.8
0.9
1.1
3.4
10.3
3.4


YKR097W
1.3
2.4
1.3
3.3
1.1
1.7
3.7
2.5
1.9
3.3


YLR303W
7.3
9.8
12.1
1.1
1.1
3.0
3.6
5.3
18.6
5.6


YNL274C
1.4
18.7
2.6
1.9
0.7
4.2
2.0
2.3
6.3
5.3


YOL151W
6.7
3.8
9.1
1.3
1.3
8.4
4.4
6.7
22.8
17.0


YOR226C
1.3
2.2
1.7
1.1
1.3
1.2
1.2
1.2
1.3
5.9


YJL153C
1.3
1.7
1.7
17.6
0.7
0.8
2.3
1.3
3.9
2.5


YOR153W
1.6
0.9
5.1
1.1
1.0
7.4
2.6
0.5
3.2
1.2


YPL088W
3.3
1.3
0.6
2.5
1.5
7.1
3.7
1.9
0.6
2.8


YDL124W
2.1
8.5
5.7
1.7
0.7
3.4
2.9
2.1
3.3
5.3


YDL174C
0.9
1.8
0.9
1.3
0.5
1.7
3.6
0.8
0.5
1.7


YGL156W
1.3
2.5
1.8
2.2
1.4
2.1
2.1
1.4
5.6
2.4


YGR157W
1.0
0.9
5.2
0.8
1.2
1.0
0.8
0.7
3.3
2.0


YHR043C
1.3
1.8
1.2
1.7
0.9
2.2
2.9
3.0
1.2
1.0


YHR044C
1.3
1.3
1.7
1.5
1.2
3.3
2.6
2.0
1.1
1.1


YJR073C
1.1
2.4
2.7
2.7
0.6
2.2
2.9
1.0
6.8
2.8


YOR303W
1.1
2.2
0.5
1.0
1.2
1.8
1.2
1.6
0.9
5.2


YBR294W
6.3
12.0
0.9
2.6
1.4
1.2
1.1
1.0
5.2
5.2


YCL043C
0.6
3.7
2.5
0.7
0.9
1.3
1.0
0.8
1.6
1.2


YCL050C
1.0
1.1
1.9
0.7
1.4
1.2
1.2
1.2
3.0
2.9


YCR012W
1.1
1.5
5.1
1.2
1.1
2.5
1.4
0.8
1.4
1.5


YDR158W
1.1
0.5
1.8
0.8
1.3
1.0
0.8
1.2
1.1
1.7


YDR204W
0.9
2.3
3.0
1.4
1.0
2.2
2.2
1.1
5.7
3.7


YDR313C
1.2
1.2
1.2
1.4
1.3
1.4
1.5
1.2
4.7
2.6


YDR368W
2.0
2.2
2.2
1.8
1.0
3.0
2.1
1.7
3.8
3.8


YER091C
3.6
3.9
30.7
1.3
0.9
2.3
2.1
0.9
5.8
1.4


YFR053C
1.7
1.4
3.0
2.2
0.9
3.2
2.1
2.8
0.6
1.1


YGL062W
0.6
1.3
1.1
0.6
0.9
1.0
1.3
0.8
1.6
2.5


YGL157W
0.7
0.9
1.8
0.9
1.5
5.4
3.3
1.4
0.6
1.8


YGL184C
4.6
15.9
57.4
1.3
1.1
1.0
1.2
1.9
37.9
66.8


YGR032W
1.0
1.4
1.0
1.3
0.7
1.9
0.8
0.6
0.5
0.7


YGR124W
0.5
0.6
1.7
0.7
1.2
1.1
0.7
1.0
2.2
1.3


YGR192C
1.4
1.0
3.8
1.0
1.1
1.7
1.7
1.1
0.9
1.3


YGR244C
1.0
1.2
1.6
1.6
0.8
2.6
3.9
1.8
1.4
1.1


YGR254W
1.2
1.3
3.8
1.3
1.2
1.9
1.5
1.4
0.8
1.2


YHR018C
1.0
1.0
1.5
1.4
1.7
1.1
0.8
1.0
1.4
4.4


YIL160C
0.8
2.4
2.3
3.5
1.0
1.6
1.1
1.2
3.2
3.8


YIR017C
3.5
8.6
2.5
1.9
0.8
1.9
1.5
1.2
5.2
3.4


YJL052W
1.5
0.9
4.0
1.8
0.7
2.4
2.1
1.5
1.6
2.0


YJR009C
1.1
1.7
5.6
1.0
1.2
1.6
1.6
1.1
1.1
1.3


YJR130C
1.1
0.6
0.8
0.9
1.4
2.0
1.3
1.3
5.2
3.8


YJR149W
1.0
1.8
1.4
2.3
0.8
1.0
1.7
1.0
1.4
1.0


YKL218C
2.1
1.0
2.2
1.8
1.2
3.6
1.6
1.7
3.4
2.7


YLR027C
1.0
1.5
2.3
0.8
0.9
2.0
1.4
0.7
1.6
2.7


YLR133W
0.9
1.6
1.4
0.7
1.0
2.2
1.3
0.7
6.1
2.3


YLR155C
1.4
1.1
2.4
1.8
1.7
1.6
2.0
1.0
3.0
1.8


YLR158C
1.4
1.2
2.1
1.7
1.7
1.5
2.0
1.1
2.7
s


YLR195C
0.8
0.9
1.0
0.8
1.0
0.8
1.1
1.0
0.6
0.7


YLR345W
1.4
1.4
1.4
1.2
1.2
1.6
1.2
1.4
4.5
4.0


YML004C
0.8
1.6
2.5
1.0
0.7
1.7
2.1
1.9
3.9
2.2


YML131W
11.2
4.3
7.7
1.9
0.7
2.0
3.0
6.1
11.1
17.7


YNL071W
0.9
0.9
1.7
1.5
0.6
1.3
1.4
0.9
1.1
1.2


YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4


YOR120W
1.8
5.4
2.8
3.2
1.4
3.4
2.7
2.0
3.3
3.0


YAL023C
0.4
1.5
1.0
0.7
1.0
0.6
0.8
0.6
0.3
0.4


YAL060W
1.1
1.8
3.2
2.7
1.2
4.2
3.3
0.9
0.6
2.5


YAL062W
0.8
1.5
1.4
1.1
1.0
1.2
1.1
0.8
1.4
0.7


YBR006W
1.3
1.6
2.6
1.5
1.3
3.1
3.3
1.0
4.5
2.7


YBR056W
1.4
1.7
1.4
2.3
1.4
2.3
5.5
1.4
3.0
3.3


YBR149W
1.1
2.0
2.7
1.7
1.4
2.8
3.1
1.5
1.7
1.9


YBR284W
0.9
1.5
2.8
4.8
1.3
1.9
1.0
0.9
6.5
3.2


YCL018W
1.2
2.7
2.4
1.4
0.8
2.3
2.3
1.3
2.1
4.3


YCL040W
0.9
7.1
10.1
2.0
0.5
3.5
2.9
0.7
0.9
3.0


YDL010W
1.7
0.8
0.6
0.7
1.2
1.1
1.9
1.1
2.2
1.3


YDL024C
1.6
1.5
1.2
2.2
1.0
1.7
0.9
1.7
4.2
3.4


YDL095W
0.5
1.3
1.0
0.8
0.8
1.0
0.8
0.7
1.2
0.7


YDL245C
1.0
2.4
1.6
2.2
1.3
1.1
1.2
1.2
0.4
2.8


YDL246C
1.2
1.5
1.3
1.1
1.1
1.4
2.1
2.4
4.4
3.6


YDR001C
0.8
2.2
2.6
1.0
1.1
2.2
1.5
0.9
2.2
3.0


YDR058C
1.2
2.2
0.8
2.7
0.7
1.0
1.4
1.9
2.4
1.7


YDR072C
1.3
1.3
1.7
1.2
0.9
1.5
0.9
0.7
0.6
0.7


YDR127W
0.8
0.9
1.5
0.7
1.2
0.8
0.9
0.7
0.6
1.3


YDR261C
1.2
1.2
1.9
0.7
1.3
1.4
0.8
0.9
1.7
1.0


YDR272W
1.0
4.0
0.8
1.8
0.7
2.3
1.7
2.1
2.5
1.9


YDR497C
0.7
0.5
0.6
1.3
0.7
0.6
0.5
0.6
0.4
0.8


YDR516C
1.2
1.5
7.8
2.1
1.3
1.8
3.9
1.3
1.8
5.2


YER053C
1.6
1.8
1.9
1.7
0.6
2.8
2.8
1.3
1.3
3.9


YER096W
1.1
2.3
2.0
2.0
1.3
1.2
0.9
1.0
7.5
3.5


YER178W
0.8
0.9
3.6
1.0
0.7
2.5
1.6
0.8
1.7
1.3


YFL030W
1.6
6.0
3.1
2.0
1.1
1.3
0.6
1.6
24.5
4.9


YFL031W
0.5
1.3
2.1
0.7
1.0
0.3
0.9
0.7
1.0
0.7


YFR047C
1.3
4.0
2.7
2.6
1.2
2.0
2.0
1.0
3.0
1.5


YGL248W
1.3
1.3
0.9
0.7
1.3
2.7
1.6
0.8
0.2
2.9


YGR037C
1.0
1.2
2.2
0.8
1.0
1.1
1.4
1.4
1.7
1.4


YGR055W
2.5
5.7
12.0
0.7
1.3
1.1
0.6
1.1
5.0
2.4


YGR194C
0.9
1.0
1.3
2.1
0.8
1.9
2.2
1.2
2.4
2.1


YGR256W
1.2
1.5
2.3
0.8
0.9
6.2
1.4
2.2
3.4
2.5


YHR111W
1.4
1.3
0.8
1.9
1.5
1.3
1.6
1.3
4.5
4.2


YHR174W
1.1
1.4
3.3
1.2
1.3
1.5
1.6
1.2
1.0
1.5


YHR176W
1.8
2.0
1.1
1.4
1.0
2.3
1.4
1.3
6.3
6.4


YIL045W
1.7
1.4
1.9
2.2
1.3
1.7
1.6
1.1
2.1
3.2


YIL107C
1.5
0.8
1.1
1.5
0.8
1.0
1.6
1.3
3.5
3.5


YIL155C
1.0
0.7
1.4
3.7
1.3
1.4
2.2
1.0
2.5
2.9


YIR034C
1.2
1.1
2.5
0.6
1.1
1.3
0.8
1.7
3.2
3.5


YIR036C
1.0
1.7
2.6
1.8
0.9
0.7
1.0
1.0
3.3
1.9


YJL031C
1.6
1.2
0.5
1.3
1.7
1.6
2.3
1.8
4.7
3.6


YJL068C
1.2
2.7
3.4
1.6
0.7
1.1
1.2
1.1
6.5
3.1


YJL099W
1.2
1.2
0.3
1.3
1.9
2.0
1.8
1.0
3.1
3.1


YJL172W
0.8
2.1
1.8
1.5
0.9
3.8
1.0
0.7
0.7
1.9


YJL219W
1.2
2.5
3.1
1.6
1.2
1.5
0.9
1.5
4.0
2.3


YJR137C
2.7
2.9
4.6
0.8
0.6
1.5
0.8
1.6
9.0
4.8


YKL035W
1.0
0.9
4.8
1.2
0.8
1.2
0.6
1.0
0.8
1.2


YKL091C
1.2
1.3
1.4
2.6
1.0
2.2
1.9
1.3
2.3
3.2


YKL104C
1.0
1.0
1.6
1.2
1.4
0.9
2.3
1.1
1.4
1.8


YKL152C
1.3
1.3
1.9
0.9
1.3
1.6
1.5
1.0
0.9
1.5


YKL213C
0.9
0.8
1.0
1.3
0.7
1.0
1.0
1.1
4.8
2.1


YKL215C
0.6
1.1
1.3
0.8
1.0
2.1
1.1
1.1
1.3
1.9


YLL058W
1.0
3.8
1.4
0.9
0.8
1.4
1.5
0.9
3.5
3.6


YLR299W
1.2
1.9
1.5
1.3
0.6
0.9
0.8
1.0
4.9
2.3


YLR348C
1.1
4.5
1.2
1.2
0.9
1.9
0.9
0.9
2.1
1.3


YML054C
1.5
1.8
1.3
3.4
1.3
1.8
1.2
1.5
4.1
1.8


YML070W
0.9
1.7
2.5
1.9
1.4
2.2
3.1
1.3
4.5
3.9


YML100W
0.8
2.7
10.6
1.4
0.9
2.8
2.2
0.7
1.7
1.4


YMR008C
0.7
0.9
1.4
1.0
1.1
1.7
0.9
0.5
0.3
0.6


YMR020W
1.3
1.0
0.9
1.7
1.4
1.6
2.7
1.2
2.3
2.9


YMR105C
1.9
3.0
5.0
4.2
0.9
2.8
2.8
1.1
0.6
2.9


YMR271C
1.6
1.6
1.3
2.0
1.1
4.2
3.4
1.8
8.0
4.4


YNL012W
1.3
1.3
1.8
0.8
1.3
1.7
2.0
1.8
3.3
3.2


YNL045W
0.8
1.3
2.0
1.3
1.1
2.2
1.8
0.7
1.3
1.1


YNL104C
1.1
1.3
3.0
0.9
0.8
0.8
0.6
0.9
1.1
2.0


YNL231C
1.5
0.8
0.8
0.5
2.1
1.8
2.5
1.5
2.2
1.3


YNR019W
1.0
1.3
1.6
1.2
0.8
1.3
0.8
0.7
1.8
1.9


YNR033W
0.6
0.8
0.8
1.0
1.3
1.6
1.2
1.1
3.6
4.2


YNR059W
1.1
0.9
0.2
1.4
1.4
0.8
1.6
1.3
1.8
1.4


YOL126C
1.0
0.8
1.0
1.6
0.7
1.5
1.4
0.9
0.8
2.4


YOL153C
1.0
1.2
2.1
3.9
1.2
1.9
3.3
1.0
2.5
3.2


YOR099W
0.8
1.3
2.1
1.3
1.5
0.9
1.0
0.9
0.6
0.7


YOR130C
0.8
1.7
1.4
1.0
1.8
1.6
1.3
0.8
2.0
1.7


YOR336W
0.7
1.4
0.7
1.0
1.3
1.7
1.2
0.8
1.7
1.5


YOR347C
0.9
0.9
2.1
2.2
0.7
0.9
0.9
0.8
0.5
0.9


YPL017C
1.0
2.5
0.8
1.0
1.3
1.5
1.4
1.3
3.0
6.7


YPR026W
0.9
1.2
5.0
1.3
0.8

1.3
1.0
0.9
3.1


YAL012W
1.1
6.5
10.4
0.8
0.6
1.6
0.6
0.7
4.7
3.9


YBR029C
0.7
0.2
1.8
1.0
1.4
0.8
0.4
0.7
2.0
1.1


YBR222C
0.6
1.2
1.3
0.8
0.7
1.3
1.0
0.6
0.7
1.0


YCL009C
0.6
0.9
2.0
0.5
0.7
1.8
1.3
1.1
0.9
1.6


YCL064C
0.6
0.6
0.8
0.8
1.4
3.3
13.4
2.4
1.7
5.2


YCR098C
1.6
3.0
1.7
2.0
1.4
1.6
1.2
1.0
1.4
2.4


YDR502C
1.2
2.8
2.4
1.2
1.5
1.5
0.9
0.9
1.6
0.9


YER026C
0.8
0.6
3.3
1.0
1.2
2.5
1.6
0.8
0.9
1.5


YHR137W
0.7
1.0
2.4
1.7
1.0
0.7
0.4
0.4
0.2
0.9


YMR189W
0.7
0.8
1.9
2.8
0.4
1.9
0.8
0.4
0.7
0.9


YNL106C
1.0
1.4
0.8
1.5
0.8
1.0
0.9
0.8
0.7
1.4


YNL169C
0.7
1.4
1.4
1.2
0.7
1.4
0.7
0.8
1.1
1.1


YNL322C
0.8
0.9
1.9
0.8
1.4
1.1
0.9
0.7
0.7
0.8


YAL038W
1.0
1.0
3.0
1.4
1.4
1.3
0.9
1.1
0.1
1.1


YBR023C
0.5
0.8
1.3
1.1
0.8
0.5
0.7
0.5
0.3
0.4


YCR048W
0.5
1.1
1.0
0.6
0.9
0.2
0.9
0.8
0.8
0.5


YDR380W
0.8
0.8
0.8
1.7
1.1
0.4
0.5
0.2
0.2
0.3


YER069W
1.3
0.8
3.3
1.4
1.5
1.3
1.0
1.5
0.8
10.4


YGL022W
0.5
0.8
1.4
0.3
1.0
0.9
0.7
0.4
0.9
0.4


YGL126W
0.6
1.3
1.4
0.8
1.1
1.6

0.7
1.6
0.7


YGL209W
1.2
1.6
1.1
2.6
0.7
1.0
1.0
1.1
0.6
0.4


YGR282C
1.3
0.7
4.6
1.9
1.0
2.2
1.1
1.0
0.8
0.8


YIL154C
0.8
1.3
1.9
0.8
0.9
1.1
1.3
0.6
2.4
1.0


YJL088W
0.9
0.8
2.2
0.5
0.9
2.8

1.3
3.2
4.1


YJR148W
0.7
1.4
2.0
3.5
0.6
2.0
2.1
0.6
0.7
3.0


YLR180W
1.3
1.4
2.4
1.0
0.8
1.2
0.6
0.9
0.8
0.9


YLR273C
1.4
1.0
1.3
2.4

1.2
1.2
1.3
2.8
2.4


YLR300W
0.9
0.8
0.8
1.0
0.8
1.1
0.5
0.8
0.0
0.5


YLR307W
0.9
0.4
0.7
3.3
1.4
1.2
1.5
1.2
0.6
0.7


YMR296C
0.6
0.7
1.2
2.6
0.4
0.4
0.6
0.5
0.4
0.6


YOL058W
0.8
0.5
1.7
0.9
1.2
0.8
0.4
1.6
0.1
15.7


YBR183W
1.8
1.5
2.0
2.9
0.9
2.5
1.7
1.0
0.4
2.0


YDR019C
1.4
0.5
1.7
4.0
0.9
4.8
1.4
0.7
0.4
0.7


YIL167W
3.3
1.6
2.0
1.0
1.0
7.7
1.2
1.9
6.9
12.7


YKR039W
1.4
3.5
1.3
1.7
1.0
2.8
1.0
1.0
1.9
2.0


YNL037C
1.4
1.8
1.7
1.1
1.7
2.8
2.8
1.0
0.6
3.2


YNR002C
1.3
1.6
1.0
2.0
1.2
2.3
1.2
1.0
3.9
1.6


YOL143C
1.0
1.4
1.2
1.2
0.9
3.5
1.3
1.2
0.8
1.0


YOR136W
1.0
0.9
3.5
1.0
1.5
3.9
3.2
1.1
0.3
3.4


YAL044C
1.5
1.1
1.0
3.0
0.8
2.2
1.0
0.8
0.4
0.6


YAL054C
1.2
1.1
1.4
1.6
1.1
2.2
1.1
1.1
8.9
4.1


YAR071W
1.6
0.8
1.0
0.7
1.6
2.0
0.3
1.4
0.3
0.3


YBL001C
1.1
1.5
1.0
1.6
1.0
2.4
1.3
1.0
1.5
0.9


YBR014C
1.1
1.2
0.8
0.9
1.4
2.0
1.4
1.2
1.3
0.8


YBR035C
1.1
1.0
1.7
1.1
1.3
2.3
1.5
1.5
2.2
1.5


YBR068C
1.1
1.0
1.9
2.5
1.4
1.9

1.0
0.8
2.5


YBR111C
1.0
0.9
1.0
1.7
1.3
3.0
2.2
1.7
1.9
1.9


YCR037C
0.7
1.0
0.8
0.8
1.3
1.8
1.0
0.7
0.6
0.6


YDL022W
0.9
2.6
6.9
1.5
0.7
2.1
1.5
0.8
1.2
1.8


YDR009W
1.4
0.8
1.5
1.0
1.2
2.4
1.4
1.2
1.3
2.0


YDR410C
0.8
2.0
1.3
0.9
1.1
2.5
1.4
0.9
1.2
1.5


YDR487C
2.2
0.9
1.3
1.1
1.3
2.3
1.3
1.8
2.7
2.3


YEL011W
2.0
1.6
1.7
6.3
1.1
2.8
2.7
0.9
2.5
1.6


YFR015C
1.2
0.8
3.2
2.1
1.2
3.0
7.3
0.7
0.3
1.8


YGL001C
1.0
1.0
1.4
1.1
1.5
2.8
1.4
1.1
0.8
0.8


YGL104C
0.8
2.0
2.1
1.8
1.0
2.1
1.2
0.8
4.6
2.1


YGL154C
1.3
1.4
1.5
0.9
1.0
1.7
0.7
1.2
2.0
1.4


YGL253W
0.8
1.0
3.2
0.7
1.3
2.4
1.7
1.1
0.3
1.4


YGR060W
0.7
0.6
0.9
0.7
1.9
2.5
0.5
1.0
0.5
0.4


YHR037W
0.7
0.9
1.3
1.6
0.9
1.8
1.2
1.0
0.9
2.2


YHR092C
2.3
1.0
7.5
2.5
1.4
1.7
0.5
1.5
0.2
0.9


YHR190W
0.8
3.9
1.2
1.2
1.8
1.7
1.9
1.2
2.4
1.9


YIL033C
0.8
1.3
3.3
1.3
0.7
2.0
1.1
0.7
2.4
1.3


YIR035C
1.4
1.8
0.9
1.6
0.7
2.1
1.3
1.3
0.7
1.2


YJL132W
1.0
0.7
0.8
1.6
1.3
2.0
1.7
1.0
1.6
1.4


YJL196C
0.9
0.9
2.5
1.3
1.1
2.0
0.7
0.7
1.1
0.9


YJR142W
1.2
0.6
1.1
1.1
1.3
2.4
1.7
1.0
0.6
0.8


YKL067W
1.1
1.9
2.1
1.4
1.9
2.2
2.6
1.2
0.9
1.6


YLR142W
4.4
2.7
1.1
6.1
1.3
3.1
1.2
2.1
3.1
4.4


YML110C
1.1
0.8
1.9
1.6
0.8
2.6
2.0
1.4
2.7
2.2


YMR272C
0.7
1.0
1.6
0.7
1.1
2.6
1.0
0.8
0.4
0.6


YNL130C
0.6
0.7
2.4
0.7
0.8
2.4
1.3
0.8
1.7
2.4


YPR006C
1.9
1.5
0.5
1.9
2.0
2.4
2.8
1.5
1.5
3.9


YBR050C
2.4
1.9
1.9
3.1
1.0
4.1
2.6
1.7
5.8
3.2


YBR145W
1.5
0.7
2.8
0.9
1.1
11.5
58.8
1.0
0.1
1.1


YBR299W
1.8
0.9
1.1
3.5
1.6
0.8
3.6
2.2
1.1
5.3


YEL020C
1.0
1.5
0.8
2.9
1.5
1.3
2.4
1.2
1.4
1.1


YGL039W
0.8
1.4
2.1
1.3
1.3
1.7
4.2
1.3
0.7
2.8


YGL134W
0.9
1.3
0.5
0.8
1.4
1.2
2.3
1.4
1.1
1.4


YJR159W
1.4
2.3
1.3
1.7
0.9
1.4
2.3
2.7
5.2
2.8


YOL157C
1.0
1.1
1.3
2.5
1.4
0.9
2.7
1.4
2.3
4.8


YOR344C
1.1
1.1
0.4
0.7
1.9
2.0
2.4
1.4
0.3
0.9


YPL265W
0.7
0.4
2.3
1.1
1.0
2.3
8.9
2.3
0.2
1.2


YBR126C
0.8
1.9
5.6
1.2
0.7
2.9
2.3
0.6
1.7


YCR005C
1.1
1.9
2.0
1.2
0.9
1.6
4.4
1.2
1.5
1.5


YDR452W
1.1
1.1
1.3
0.8
1.2
2.0
1.9
1.0
1.4
1.3


YGR019W
1.2
0.8
1.4
1.7
0.8
2.4
2.4
1.2
2.9


YGR255C
0.9
1.4
1.4
1.5
1.3
3.2
1.8
1.0
2.5
1.8


YIL098C
1.4
1.6
0.5
2.0
1.7
1.7
2.2
1.6
1.9
1.9


YIL172C
1.1
1.1
1.6
1.7

1.3
2.5
1.6
2.8
7.1


YLR100W
0.8
1.4
1.3
1.9
1.8
1.8
2.3
1.0
0.9
1.0


YOR221C
0.8
1.0
0.9
1.1
1.7
0.8
2.1
0.9
1.4
1.7


YPL123C
1.2
0.8
1.8
3.0
0.8
1.9
2.7
1.2
4.2
2.3


YBR093C
2.9
1.2
1.7
1.3
1.1
0.6
0.3
1.7
0.1
0.5


YBR196C
0.8
0.6
3.9
1.4
0.8
0.8
1.4
1.1
0.3
0.9


YER023W
0.8
0.6
1.2
1.2
0.8
1.3
0.7
0.9
1.1
0.6


YFL055W
2.0
6.7
1.3
2.5
1.5
1.1
1.4
1.3
23.9
6.5


YIL124W
0.9
0.8
2.8
1.6
0.9
1.2
1.3
0.9
1.0
0.7


YMR318C
1.4
2.4
2.2
0.7
1.2
2.1
0.8
3.6
2.3
4.8


YBR067C
1.6
2.5
2.8
0.9
1.1
1.1
1.1
1.1
1.7
1.0


YBR115C
0.6
0.7
1.4
0.4
0.7
0.9
1.1
1.3
0.8
1.6


YDL131W
1.1
0.9
1.8
1.0
1.0
0.9
0.7
2.2
0.8
2.7


YDL168W
2.3
2.0
2.1
0.9
1.2
1.4
1.1
1.7
8.2
4.7


YDR216W
1.3
1.1
2.0
2.6
0.8
1.3
1.0
1.0
2.5
2.7


YDR253C
5.7
6.4
1.4
3.2
0.9
0.8
1.0
1.7
14.8
6.3


YDR513W
2.2
2.5
2.3
2.6
0.9
2.1
1.6
1.6
4.6
3.1


YER061C
0.9
0.9
1.2
2.5
0.8
0.4
0.9
0.7
0.3
0.7


YFL052W
1.3
0.8
0.7
2.3
1.5
2.1
1.4
1.3
0.6
1.2


YFL058W
1.2
1.7
1.1
1.4
1.1
2.0
0.9
1.7
3.2
2.4


YFR030W
3.1
5.5
8.5
0.5
0.8
1.8
1.1
1.7
24.1
9.0


YGL202W
0.8
0.7
2.2
0.7
0.7
0.7
0.6
1.0
1.3
1.7


YGR070W
1.1
1.0
2.0
1.5
1.4

1.4
1.8
1.1
1.5


YHL036W
2.2
4.8
3.4
2.0
1.3
1.3
1.0
1.2
9.0
4.4


YHR104W
1.0
4.1
15.7
1.9
1.1
1.2
1.5
1.1
4.8
2.3


YJL045W
1.8
2.2
1.6
5.3
0.7
0.6
0.7
0.9
9.7
1.6


YJL060W
1.8
2.6
9.6
1.0
1.4
1.3
1.3
0.8
5.3
2.8


YJL155C
2.1
5.0
0.8
2.4
0.8
0.8
2.0
1.5
3.8
2.8


YJR109C
0.8
0.7
1.4
0.9
0.7
0.9
0.8
1.0
1.8
4.3


YJR156C
1.6
3.2
2.4
1.8
0.9
0.9
1.3
1.5
3.4
2.8


YLR092W
5.0
7.5
1.4
0.6
1.3
1.0
1.3
1.5
12.7
5.8


YMR081C
3.5
1.4
2.0
5.8
1.7
1.1
0.9
1.7
0.3
2.2


YMR250W
0.9
5.1
5.6
1.3
0.6
4.5
3.0
0.9
6.1
2.4


YNL277W
5.7
10.3
5.3
0.6
1.1
1.7
1.4
2.2
55.0
10.9


YOR184W
1.1
0.9
2.1
2.1
1.0
0.6
1.2
0.7
0.9
0.7


YPR160W
1.4
3.8
3.6
3.3
0.7
4.5
1.8
0.9
0.9
1.3


YDL182W
0.8
0.7
1.3
0.8
1.3
1.0
1.0
2.9
0.8
2.4


YBR291C
2.0
0.9
1.0
1.5
0.9
1.1
0.9
2.2
0.9
1.0


YIL094C
1.5
0.4
0.8
0.7
1.4
1.2
1.3
3.6
0.3
0.4


YNR050C
1.7
0.5
1.2
0.6
1.3
0.9
1.0
2.2
0.4
0.7


YDL244W
1.1
3.5
1.8
1.6
0.9
1.3
1.7
1.8
2.5
3.7


YDR054C
1.3
1.0
0.7
1.4
0.7
1.0
1.1
1.5
2.9
3.2


YDR353W
0.9
1.6
3.4
1.6
0.6
0.9
1.0
1.1
2.0
5.1


YEL070W
1.4
0.9
1.6
3.4
1.3
1.2
1.3
1.2
1.9
13.0


YIL168W
2.8
1.4
1.0
1.2
1.4
0.7
1.3
1.6
7.8
19.3


YJL221C
1.1
1.0
1.1
1.3
0.9
6.6
2.5
1.8
2.7
4.4


YJR095W
1.2
20.5
1.9
6.7
1.2
1.5
2.0
0.9
0.5
6.3


YKL085W
1.4
2.3
1.6
1.2
1.2
1.9
1.5
1.2
1.9
3.0


YKL188C
1.3
0.7
1.9
2.4
1.0
0.8
1.1
0.7
2.5
2.8


YKL217W
1.8
2.4
1.0
2.1
1.1
1.2
1.6
1.1
0.9
4.1


YKR061W
2.0
0.9
0.5
1.9
1.2
1.2
1.4
1.5
1.5
2.6


YLR174W
1.2
1.5
1.7
2.1
0.9
0.9
1.6
1.1
2.5
8.3


YLR260W
1.1
1.5
1.5
2.4
1.2
1.0
1.2
1.2
2.6
3.2


YNL009W
1.1
1.9
2.0
1.4
1.4
1.1
1.2
1.1
1.4
3.3


YNL117W
0.9
4.7
1.7
0.8
0.8

1.1
1.7
12.8
4.4


YNL183C
0.9
3.5
6.4
1.3
0.7
1.2
1.3
0.9
4.8
4.3


YNR073C
1.1
1.4
0.8
2.7
1.4
1.7
2.2
1.5
2.5
16.8


YPL161C
1.0
1.7
1.1
1.1
0.8
0.7
1.3
1.8
1.2
2.7


YAL061W
1.7
2.4
3.3
3.8
1.0
1.0
2.0
0.8
5.5
1.4


YAL067C
2.7
7.5
1.5
1.4
0.7
1.2
0.8
1.1
7.6
2.9


YBL033C
1.3
1.9
2.4
1.0
1.1
0.4
0.9
1.4
6.6
4.2


YBL086C
0.8
0.5
1.0
0.6
1.3
0.7
1.0
1.1
3.3
1.4


YBR117C
0.8
1.6
1.5
1.4
0.9
2.3
1.0
0.7
5.9
1.5


YBR213W
1.0
1.6
1.0
0.5
1.1
2.4
1.3
1.3
11.4
2.3


YCR036W
1.3
1.2
1.3
1.3
1.5
1.4
1.5
1.1
2.6
1.5


YDL132W
0.8
1.2
1.1
0.7
1.3
0.9
1.4
1.0
3.8
2.4


YER014W
1.0
0.9
0.9
0.6
0.8
4.0

1.2
3.5
1.1


YER042W
3.0
2.2
3.1
1.0
1.1
1.6
1.1
1.7
6.8
2.1


YER090W
1.0
1.1
2.0
0.7
1.3
0.7
0.9
1.4
3.7
2.5


YGL026C
0.7
9.3
1.9
0.6
1.2
1.7
0.9
0.8
3.7
1.5


YGL252C
1.1
2.4
1.4
0.7
1.3
0.8
1.4
1.2
2.7
1.7


YGL254W
1.2
1.1
0.8
0.6
1.1
0.7
1.3
1.4
3.1
1.8


YGR276C
0.9
0.8
0.3
1.3
1.5
0.7
1.9
1.5
4.5
2.2


YHR106W
0.9
1.7
1.7
1.5
1.7
1.3
1.2
1.0
2.8
2.5


YIL046W
1.5
2.7
1.6
0.7
1.4
0.9
1.0
1.0
10.7
2.5


YJL071W
1.0
1.5
1.3
1.6
1.4
1.0
1.3
1.1
2.8
2.2


YJR139C
1.4
2.6
2.9
1.1
1.2
1.8
1.3
1.1
4.1
1.9


YKR069W
3.4
6.3
5.0
3.1
0.7
0.5
1.0
1.2
10.9
9.0


YLL061W
3.6
2.8
9.2
0.4
0.8
0.8
0.9
1.4
3.7
5.5


YLR070C
1.0
1.3
1.4
1.1
0.7
1.1
1.3
1.0
3.5
1.6


YLR099C
2.0
2.2
1.4
0.8
0.9
0.4
0.2
1.2
3.6
1.1


YLR157C
1.1
1.1
3.4
1.1
1.3
1.9
1.9
1.5
5.1
1.8


YLR160C
1.2
1.4
3.9
1.1
1.3
1.8
1.9
2.0
4.8
1.8


YLR164W
1.0
2.4
0.3
1.0
1.2
1.2
1.1
1.2
5.3
2.0


YML042W
0.9
1.4
1.5
2.2
1.0
0.9
0.8
1.6
3.8
2.4


YOL049W
0.9
1.1
1.3
0.9
1.4
0.6
1.1
1.0
3.0
1.9


YOL064C
1.4
2.1
1.1
0.6
0.9
1.4
1.2
1.0
8.7
2.7


YOR377W
0.6
0.6
0.6
1.0
1.4
1.6
1.6
1.0
3.8
1.1


YPL031C
0.9
2.0
1.4
0.8
1.5
1.8
1.6
1.0
5.7
1.4


YPL113C
1.4
1.7
0.4
2.4
1.3
1.0
1.9
1.4
5.5
2.0


YPL274W
0.8
4.2
3.8
0.8
0.6
1.1
0.7
0.9
4.1
3.6


YPR048W
1.3
2.0
0.9
1.1
0.9
0.6
0.9
1.5
4.0
2.1


YBR001C
0.9
1.4
1.1
1.4
0.9
1.1
0.9
1.3
2.3
2.1


YBR018C
0.9
1.1
1.9
2.9
0.9
0.7
1.4
0.6
1.3
1.7


YBR204C
1.0
1.0
1.5
1.8
1.1
0.9
1.7
1.1
1.8
1.9


YBR241C
0.9
9.3
2.6
0.9
0.9
1.5
1.4
0.7
29.8
2.2


YCR105W
2.2
1.2
1.2
3.0
0.9
1.0
1.0
1.4
2.0
3.9


YDR287W
1.1
8.4
1.9
1.2
1.2
1.6
1.2
1.2
2.5
1.8


YDR294C
0.7
1.1
1.9
1.2
0.9
0.7
1.0
1.0
2.0
2.9


YER052C
1.1
1.0
3.6
1.1
0.6
0.6
0.5
1.0
2.7
2.4


YFL021W
0.8
1.4
2.4
1.7
1.1
0.8
0.8
0.6
2.7
1.2


YGL040C
0.7
1.2
1.4
0.9
1.3
2.0
1.1
1.0
2.1
1.9


YGL125W
1.0
3.2
4.3
0.7
0.9

1.7
0.8
2.1
2.1


YGR007W
1.3
1.7
0.7
1.6
0.6
0.8
1.2
1.1
2.2
2.3


YGR155W
1.3
4.4
1.2
0.6
1.3
1.6
1.1
1.4
2.4
1.7


YIL099W
0.9
1.6
1.5
0.4
0.8

101.4
1.0
2.2
1.8


YIL170W
1.1
1.0
2.5
2.2
0.9
8.8
0.5
1.2
5.7
3.2


YIR031C
0.8
1.6
0.6
0.6
1.6
1.7
1.4
1.0
2.6
1.0


YIR032C
1.1
1.9
1.3
2.6
1.0
0.6
1.0
1.2
2.6
2.3


YJL128C
0.8
1.4
0.4
0.8
1.2
1.3
1.8
0.9
2.0
1.7


YJR090C
0.8
1.0
0.6
0.8
1.2
1.2
0.8
0.8
1.9
1.2


YJR103W
1.1
3.8
1.2
1.6
0.7
0.6
0.6
0.8
1.8
3.0


YJR153W
1.1
1.7
1.1
0.8
0.9
0.4
1.3
0.9
2.4
1.6


YKL192C
1.1
1.0
3.7
1.1
1.1
1.8
1.1
0.9
3.5
1.6


YLR025W
1.2
5.1
0.7
1.1
1.9
1.5
1.7
1.5
2.4
1.5


YML051W
1.0
1.4
1.8
0.9
1.0
0.7
0.9
0.9
2.0
1.5


YML099C
0.6
1.0
1.1
1.3
1.0
0.5
1.0
0.7
2.2
1.7


YMR056C
1.1
1.3
1.7
1.0
1.1
0.9
1.4
1.2
1.8
1.1


YNL257C
0.7
1.0
0.9
0.8
0.9
2.0
1.1
1.1
2.1
1.4


YNL264C
1.0
2.4
1.3
1.0
0.8
1.4
1.5
1.1
3.3
1.3


YNR071C
1.4
1.0
0.9
3.2
1.1
0.9
1.4
1.2
3.1
7.0


YOL065C
1.0
1.7
1.6
1.3
0.8
1.3
1.9
1.0
2.1
1.8


YOL067C
0.8
0.9
0.9
1.4
0.7
0.3
0.7
1.0
2.1
1.3


YPL147W
1.0
0.8
2.3
1.2
1.2
1.1
1.0
0.9
2.4
2.4


YDR043C
2.8
1.1
1.2
6.9
1.7
1.4
1.3
1.2
1.0
2.7


YGR180C
3.1
1.1
1.9
1.0
2.0
0.6
0.5
1.0
1.4
1.5


YJL026W
2.5
2.4
2.9
1.0
1.7
1.4
0.5
1.2
1.0
1.1


YGR087C
1.0
15.0
1.7
0.6
1.0
1.1
1.0
0.8
0.2
0.9


YGL256W
0.9
5.3
1.1
1.3
0.7
0.7
0.5
1.0
0.4
1.2


YAL039C
1.1
2.2
1.7
1.0
1.1
0.8
1.0
1.2
1.6
2.2


YJR107W
1.0
3.1
1.5
1.8
0.7
1.5
1.3
1.3
1.4
0.9


YNL142W
0.7
2.4
2.5
0.8
1.3
0.9
1.1
0.8
0.9
0.6


YDL210W
1.2
2.2
2.7
1.1
0.9
1.3
0.8
1.1
1.2
1.4


YGL055W
1.1
1.8
0.3
2.5
1.5
1.6
0.6
1.4
0.2
0.7


YCL025C
1.1
4.6
2.5
1.7
0.9
0.9
0.7
0.7
0.3
0.3


YBR132C
0.9
1.9
2.4
1.8
0.8
1.2
1.1
0.8
0.8
1.1


YHL018W
0.8
1.5
0.5
0.5
0.9
0.4
1.2
0.8
0.8
0.6


YPL038W
0.8
1.5
0.2
1.1
1.4
0.5
1.0
1.2
0.9
0.7


YKR053C
0.9
2.0
1.0
1.2
1.0
1.1
1.7
0.9
0.8
1.8


YNL256W
0.7
1.6
0.6
0.6
1.0
0.5
0.6
0.9
0.8
0.6


YLR377C
1.1
2.6
1.8
1.2
1.0
0.7
0.9
0.7
1.8
1.6


YBR253W
1.3
4.4
0.4
1.1
1.4
1.3
1.4
1.8
1.8
1.5


YBL030C
1.0
0.9
4.5
0.9
0.7
1.1
0.9
0.8
0.4
0.9


YBR221C
0.8
0.7
3.2
1.5
1.3
1.7
1.5
0.8
1.0
1.3


YDR342C
2.8
1.1
12.2
5.7
1.6
1.1
0.8
1.2
0.2
2.2


YDR343C
1.2
1.0
20.6
4.6
1.3
1.3
0.7
1.2
0.3
2.1


YEL034W
0.9
0.6
3.3
0.9
1.4
0.9
0.4
0.9
0.8
1.0


YHR094C
0.7
1.2
5.3
1.6
1.1
1.6
0.8
1.2
0.3
1.2


YIL162W
1.3
1.5
6.8
2.4
1.2
1.0
1.2
1.6
0.8
3.7


YJR105W
0.6
0.7
3.0
0.8
0.7
0.3
0.5
0.8
0.9
0.5


YLR134W
0.8
0.6
2.3
0.8
1.3
2.5
1.1
0.8
0.1
0.7


YLR258W
1.5
1.0
4.2
3.5
0.9
1.8
1.8
0.9
0.8
1.3


YML058W
1.9
1.2
5.8
1.9
0.6
0.6
0.6
0.7
1.1
1.2


YMR083W
1.4
1.7
2.6
1.1
1.5
1.8
1.7
1.1
0.4
1.1


YOR178C
1.4
1.3
4.8
2.3
1.0
2.7
0.9
0.9
0.2
1.7


YPL028W
0.7
0.9
2.6
0.9
1.0
1.2
1.3
0.9
1.2
0.8


YPR113W
1.1
0.8
3.7
1.3
2.0
1.1
1.2
0.9
0.4
0.8


YPR183W
0.9
1.5
3.5
0.8
0.9
1.2
1.2
1.0
0.9
0.6


YBR011C
1.3
1.8
2.5
1.1
0.9
2.0
1.1
1.3
2.2
1.0


YCR034W
0.8
0.4
2.5
0.9
0.9
0.3
0.3
0.9
0.1
0.2


YDR050C
1.6
1.3
2.3
1.8
0.9
1.7
1.5
1.3
0.4
1.3


YDR178W
2.0
2.0
3.4
2.2
0.9
2.1
0.6
0.9
0.9
0.8


YDR284C
0.8
1.5
3.0
2.9
0.8
1.8
1.4
0.9
0.9
1.0


YDR345C
0.8
0.9
5.6
2.6
1.3
1.2
1.1
1.2
0.2
1.1


YDR400W
1.0
2.0
2.2
0.7
1.0
1.1
0.6
1.4
1.1
1.4


YEL063C
0.7
0.8
2.4
1.3
1.2
1.3
0.7
0.6
0.8
1.7


YER081W
1.6
1.9
2.7
1.4
1.1
1.1
0.5
0.6
1.8
1.1


YER120W
0.9
1.1
2.5
0.8
0.8
1.5
0.9
0.6
0.8
0.9


YFL011W
1.2
0.7
3.7
3.3
1.3
1.0
0.8
0.8
0.3
1.6


YGL012W
1.0
0.8
3.0
1.2
1.5
1.6
0.9
0.8
0.3
0.9


YGR191W
0.8
0.7
1.6
1.5
0.8
1.1
0.7
0.7
0.1
0.7


YGR204W
0.5
1.1
2.7
1.3
0.6
0.6
0.8
0.4
0.9
2.3


YHR025W
0.6
0.8
2.4
0.6
0.9
0.8
0.8
0.8
0.2
0.4


YHR123W
0.7
1.2
1.8
1.0

1.0
0.9
0.8
0.8
1.1


YJL121C
1.0
0.5
1.9
0.8
1.0
1.1
0.7
1.0
0.1
0.4


YJR077C
1.1
1.1
2.0
1.6
0.9
0.9
0.7
0.8
0.4
0.7


YJR143C
0.6
0.6
2.1
0.8
1.6
0.6
0.5
0.7
0.1
0.3


YKL060C
1.6
0.8
2.5
1.0
1.6
1.3
1.2
1.1
0.3
0.8


YKL148C
0.9
0.8
3.7
0.7
0.8
0.5
0.6
0.8
1.7
1.7


YKL157W
0.7
1.0
2.3
1.3
1.5
1.5
1.9
1.1
1.7
1.9


YLR044C
0.8
0.6
2.2
0.9
1.7
1.5
1.3
0.7
0.0
1.2


YLR056W
1.0
0.6
2.5
0.8
1.6
1.2
0.8
0.9
0.0
0.5


YLR058C
0.9
0.8
5.5
2.6
0.7
0.9
0.5
0.3
0.2
0.1


YLR081W
1.3
0.8
2.8
3.6
1.0
0.9
0.7
0.9
0.1
2.2


YLR089C
0.9
1.2
2.1
0.9
0.8
1.5
1.6
0.7
0.5
0.8


YLR284C
0.9
1.0
3.8
1.9
1.6
0.9
0.8
1.2
0.9
0.9


YLR304C
0.7
0.6
5.0
0.7
0.6
1.9
0.6
0.6
0.1
2.2


YLR354C
1.1
2.5
2.3
1.5
1.6
1.5
1.1
1.4
0.4
0.9


YLR372W
0.7
0.3
1.7
0.8
1.4
0.5
0.2
0.9
0.0
0.1


YML022W
0.9
0.6
2.0
1.1
1.3
0.8
0.6
1.1
0.3
0.6


YMR011W
1.3
1.0
9.4
5.5
0.9
0.6
0.8
1.1
0.0
0.7


YMR015C
0.7
0.7
1.9
0.9
1.7
1.3
0.4
0.7
0.1
0.3


YMR205C
0.5
0.7
2.3
0.8
1.2
1.2
0.9
0.7
0.3
0.8


YMR261C
0.7
1.6
3.6
0.8
0.9
0.6
1.3
0.7
1.6
1.3


YMR323W
0.8
1.1
2.9
1.1
0.7
0.4
1.1
0.8
0.5
1.3


YOL086C
1.1
0.5
2.2
1.1
1.9
1.7
1.9
0.8
0.1
1.2


YOL156W
1.1
0.7
2.5
1.1
1.2
1.2
1.0
1.0
2.3
2.1


YOR002W
0.8
1.1
1.9
0.9
1.1
1.1
1.0
0.9
0.8
0.9


YOR085W
0.7
0.8
1.9
1.0
1.0
0.6
0.6
0.7
0.5
0.6


YOR108W
0.8
0.9
2.3
0.6
1.1
1.6
1.2
0.9
0.4
1.1


YOR128C
0.9
0.7
2.1
2.1
1.1
1.0
0.7
0.6
0.3
0.4


YOR142W
1.0
1.2
3.4
1.0
1.4
1.6
1.0
0.8
1.1
1.5


YOR176W
0.7
2.6
2.7
0.9
1.0
0.9
0.5
1.0
1.0
0.5


YPL057C
1.9
1.1
3.2
3.1
1.9
0.6
0.6
1.0
0.4
1.4


YPL135W
0.9
1.2
2.5
1.2
1.6
1.3
1.2
1.0
0.5
2.8


YCR010C
1.6
1.6
1.6
4.2
1.7
1.3
1.3
0.8
0.9
4.7


YBR003W
0.9
0.8
1.0
1.9
0.7
1.2
1.1
0.9
1.0
1.3


YBR020W
1.0
0.5
1.9
1.9
1.0
0.8
0.7
1.0
−0.4
1.1


YDR123C
1.2
0.8
0.4
2.1
1.6
0.7
0.9
1.3
0.5
0.6


YDR277C
1.6
1.2
1.0
3.0
0.8
1.1
1.2
1.7
0.2
0.9


YDR408C
1.0
1.0
1.4
4.1
0.9
0.9
0.8
0.7
0.3
0.5


YDR483W
1.1
1.0
1.3
2.0
0.7
1.5
0.8
1.0
0.4
1.1


YGL115W
0.9
0.6
1.2
2.0
1.2
1.2
1.4
1.0
1.2
1.2


YGR096W
1.5
1.0
1.1
4.6
1.2
1.7
0.9
1.0
0.8
0.8


YGR288W
0.9
0.5
1.0
2.6
0.8

1.4
1.0
1.6
2.6


YHR210C
1.3
1.0
0.6
5.2
1.8
0.7
1.9
1.3
−0.1
0.9


YIL006W
1.0
1.1
1.4
2.9
0.8
0.3
0.8
0.6
0.9
1.1


YKR034W
0.9
1.5
1.1
4.7
0.9
0.9
0.7
1.5
0.5
0.6


YLR006C
0.7
0.7
0.9
6.2
1.6
0.9
1.1
0.9
1.1
1.1


YNL025C
0.9
1.4
1.4
12.8
0.7
0.5
1.2
1.0
1.1
1.8


YOL116W
1.1
1.0
0.9
2.8
1.7
0.7
1.5
1.3
0.6
1.8


YOR103C
1.1
0.8
1.3
1.8
1.5
1.0
1.2
1.0
0.8
0.9


YOR251C
1.1
1.0
1.3
1.8
0.8
0.9
1.0
1.1
0.8
0.8


YOR348C
1.1
0.7
1.2
2.0
0.9
0.7
0.8
0.8
0.5
0.4


YPL148C
1.2
0.8
0.9
2.3
1.1
0.6
1.0
0.9
0.7
1.5


YGL205W
0.9
0.9
0.7
0.8
1.1
1.6
0.8
1.2
0.5
0.6


YNL192W
1.1
1.2
1.5
1.6
0.9
0.6
1.0
0.8
0.6
1.8


YOL108C
1.4
1.5
0.4
1.9
2.1
0.9
1.1
1.3
1.6
0.9


YPR165W
1.3
0.7
1.6
1.0
1.5
1.8
1.0
1.0
0.9
0.7


YDR073W
1.7
0.9
0.7
1.4
1.2
1.3
1.2
1.3
0.5
1.2


YER015W
0.7
0.9
1.1
1.5
1.3
0.9
1.2
1.1
0.4
0.9


YJL167W
0.9
1.4
1.4
1.1
0.7
1.3
1.5
1.5
0.9
0.9


YJL216C
0.8
4.7
2.2
0.9
0.8

1.5
1.9
1.5
1.3


YKR009C
1.0
1.2
1.5
0.9
1.0
1.8
1.0
0.9
2.4
2.1


YOR180C
0.8
1.1
1.0
1.0
1.0
0.7
0.8
0.9
0.3
0.4


YBR036C
0.8
1.7
1.8
1.2
1.2
1.3
1.3
0.7
1.0
1.0


YDR297W
1.5
0.8
0.8
1.1
0.9
1.4
0.6
1.5
0.3
0.7


YDR387C
0.8
0.9
1.2
2.2
0.9
1.2
1.3
0.7
1.4
2.0


YOL096C
1.1
1.0
1.2
1.6
1.2
1.3
1.7
1.0
1.3
1.4


YPR184W
1.2
1.4
5.7
2.2
0.9
1.5
1.3
0.7
1.9
3.2


YBR298C
1.1
1.0
1.6
2.3
1.4
0.4
1.7
0.5
0.3
1.1


YDL078C
0.7
1.1
1.2
0.8
1.3
1.1
1.7
1.0
1.1
1.0


YDL215C
1.0
1.5
1.0
1.6
1.5
0.9
1.9
1.1
1.7
2.4


YGL035C
0.7
1.4
4.3
1.4
1.1
0.6
1.2
1.3
0.9
1.5


YGR287C
1.3
1.0
1.3
1.5
0.8
0.8
2.2
1.3
2.6
4.2


YJL070C
1.3
0.9
1.1
1.2
1.3
2.0
1.4
1.1
1.0
1.1


YLR351C
1.0
1.4
1.3
1.5
1.3
1.4
1.4
1.2
0.8
1.2


YLR375W
0.9
1.5
0.9
0.9
1.0
1.3
0.9
1.0
1.6
1.2


YMR267W
0.8
1.8
0.7
0.9
1.0
1.4
1.2
1.5
0.4
0.8


YMR278W
0.7
1.7
1.4
1.0
1.2
1.3
1.8
1.1
1.4
1.7


YMR293C
0.9
1.5
1.6
2.2
0.6
0.5
1.2
1.0
0.7
1.3


YNR072W
1.1
1.5
0.5
0.7
1.0
0.9
1.5
0.9
0.7
1.8


YOR363C
0.8
2.0
0.9
1.3
0.7
1.2
0.7
1.1
1.2
1.6











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YCR107W
23.0
0.9
4.0
8.3
4.8
3.1
1.3
1.1
0.59


YDL243C
19.6
1.1
4.1
12.0
4.2
3.0
1.8
1.5
0.76


YFL014W
5.0
4.3
15.2
7.3
6.3
14.2
1.5
8.8
2.14


YFL056C
68.3
1.0
4.7
7.8
5.0
3.4
1.0
1.1
0.55


YFL057C
27.7
1.0
4.1
23.4
3.1
3.9
1.6
1.3
0.71


YJR155W
15.4
1.0
5.7
9.4
2.6
5.6
1.3
1.4
0.64


YNL331C
21.8
0.9
3.1
7.5
2.3
4.0
1.7
1.3
0.58


YNL332W
2.6
1.2
2.1
3.0
5.4
2.2
1.0
1.0
0.24


YOL165C
17.6
0.8
3.7
9.1
3.0
1.8
1.6
1.0
0.69


YPR167C
1.9
1.3
1.9
4.2
0.9
0.9
1.7
1.4
0.54


YBR256C
3.2
1.7
3.5
5.6
1.6
3.0
2.6
3.3
1.97


YBR296C
1.5
1.6
2.0
2.3
1.7
0.3
3.8
4.0
0.54


YDL021W
4.7
2.4
5.3
3.7
0.7
7.3
1.9
3.2
0.47


YFL061W
1.1
0.9
1.2
6.0
2.1
1.0
1.2
0.9
0.31


YGR043C
3.6
3.3
6.9
4.1
3.0
13.7
1.6
4.8
0.66


YHR112C
1.5
1.9
3.9
2.4
2.0
2.7
1.6
1.8
0.55


YIR030C
1.4
0.9
1.3
2.9
0.7
0.8
0.9
1.0
0.42


YJR010W
2.9
1.4
3.2
5.4
1.7
1.7
1.2
1.0
0.56


YKL001C
2.6
2.1
1.6
6.2
1.1
1.8
2.7
1.7
0.91


YKR097W
0.8
1.8
17.5
2.1
2.5
2.2
1.1
1.5
0.16


YLR303W
9.8
4.3
9.9
3.8
5.8
3.4
1.5
1.4
1.42


YNL274C
4.0
1.1
2.3
3.3
2.5
6.4
1.4
2.6
0.85


YOL151W
9.0
4.6
16.9
4.0
2.8
3.7
4.0
5.6
1.12


YOR226C
1.5
0.6
0.9
2.7
1.0
0.7
1.0
0.7
0.58


YJL153C
0.7
10.2
38.0
1.4
37.0
1.0
6.5
1.8
0.27


YOR153W
1.0
4.0
11.8
0.3
3.6
1.6
2.5
3.1
1.91


YPL088W
1.1
3.6
4.8
1.6
3.2
4.3
9.1
8.3
0.69


YDL124W
3.4
2.4
6.0
1.6
3.4
3.6
2.2
2.6
2.43


YDL174C
0.9
2.8
5.9
1.1
0.6
5.1
2.2
4.0
0.63


YGL156W
2.1
2.6
6.0
1.6
3.0
4.1
1.4
1.9
0.29


YGR157W
1.0
1.8
4.8
0.7
4.6
1.0
0.8
1.3
2.10


YHR043C
1.6
2.2
2.7
1.3
2.1
2.2
1.4
1.7
1.38


YHR044C
1.7
2.3
4.3
1.3
1.5
2.4
1.3
1.4
1.12


YJR073C
2.8
4.1
10.0
2.3
28.9
3.7
2.9
2.6
0.99


YOR303W
0.9
1.9
3.3
1.6
4.1
1.2
1.2
0.8
1.47


YBR294W
1.2
1.0
3.1
1.3
1.0
0.9
1.0
0.9
0.18


YCL043C
1.7
1.5
4.1
0.6
5.7
0.8
0.9
1.0
2.37


YCL050C
1.3
1.2
2.8
1.2
0.8
0.7
1.0
1.0
2.20


YCR012W
1.8
1.2
4.1
0.9
1.4
1.4
0.8
1.3
4.48


YDR158W
1.6
1.0
2.6
0.9
1.0
0.6
1.0
0.9
3.54


YDR204W
2.2
1.2
2.9
1.1
0.6
2.8
1.1
1.7
0.62


YDR313C
1.5
1.2
2.3
1.3
0.8
2.9
1.1
1.3
0.84


YDR368W
1.8
1.4
2.6
2.0
1.2
2.3
1.1
2.0
1.70


YER091C
3.2
2.0
5.4
1.2
10.2
2.7
1.2
1.0
1.23


YFR053C
1.5
1.7
3.0
0.6
0.6
3.0
1.4
2.2
4.17


YGL062W
0.7
1.6
4.5
1.2
2.7
1.5
1.1
0.9
0.77


YGL157W
1.4
1.5
4.8
1.2
5.1
1.7
1.8
2.3
1.69


YGL184C
1.7
2.6
7.4
1.4
0.4
1.5
1.0
0.9
0.16


YGR032W
1.5
1.5
3.9
1.1
5.4
1.5
3.2
2.8
1.18


YGR124W
1.1
1.1
2.3
0.5
1.5
0.3
0.7
0.6
3.56


YGR192C
2.3
2.2
3.4
1.0
1.9
1.1
1.1
1.3
7.49


YGR244C
1.8
1.9
2.6
1.2
2.0
2.6
1.9
3.1
1.12


YGR254W
1.3
1.7
3.1
0.6
2.4
1.4
1.3
1.2
7.01


YHR018C
1.4
1.4
3.3
1.0
4.4
1.0
1.9
1.2
1.21


YIL160C
2.4
1.0
2.3
1.5
5.6
8.8
2.4
3.0
0.27


YIR017C
4.2
1.2
3.4
1.9
2.3
3.0
1.5
1.3
0.36


YJL052W
4.3
2.4
5.6
1.3
2.3
2.3
1.2
1.9
6.19


YJR009C
1.1
1.5
2.7
1.0
2.1
1.5
1.1
1.3
5.86


YJR130C
1.7
1.0
2.9
1.1
0.9
1.5
1.1
1.3
0.62


YJR149W
0.7
1.0
3.5
1.4
1.4
2.4
1.1
1.2
0.34


YKL218C
1.7
1.2
5.1
1.4
0.8
3.1
2.5
2.6
0.60


YLR027C
1.6
1.3
2.5
1.0
1.4
0.9
1.3
1.3
1.39


YLR133W
0.6
1.5
3.3
1.1
1.9
1.0
1.1
1.3
0.36


YLR155C
2.0
1.1
3.3
1.1
1.2
2.2
1.4
2.2
1.63


YLR158C
2.4
1.1
3.2
1.2
1.1
2.1
1.4
2.0
1.57


YLR195C
0.8
1.3
2.3
0.7
0.9
0.8
0.9
1.0
1.55


YLR345W
2.5
1.6
3.5
1.5
1.0
1.2
1.2
1.4
2.65


YML004C
2.2
1.1
2.4
1.4
2.1
4.5
1.5
2.4
2.41


YML131W
14.4
1.1
2.4
2.7
2.2
1.6
2.5
3.0
1.15


YNL071W
1.6
1.3
2.5
0.8
1.1
1.1
1.0
1.2
1.61


YNL241C
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68


YOR120W
3.0
1.2
3.6
2.4
1.5
3.9
1.3
2.6
1.06


YAL023C
1.7
1.2
2.3
0.4
2.5
0.4
1.0
0.7
1.49


YAL060W
2.4
0.8
2.2
0.9
0.9
3.2
1.1
1.8
2.39


YAL062W
1.2
1.0
2.1
0.8
1.1
1.3
1.0
0.8
0.86


YBR006W
1.9
1.1
2.2
1.1
1.1
3.0
1.2
1.8
0.62


YBR056W
1.8
1.4
3.0
1.0
0.7
2.8
2.4
3.4
1.13


YBR149W
1.9
1.4
2.2
1.2
0.7
2.7
2.1
3.4
2.72


YBR284W
1.4
1.2
2.8
1.6
0.8
0.8
1.1
1.0
0.25


YCL018W
3.7
1.6
3.2
1.0
0.6
2.3
1.3
1.0
0.99


YCL040W
8.2
2.3
5.6
0.7
3.4
3.1
1.4
1.7
1.98


YDL010W
1.3
0.9
2.0
2.2
1.4
1.4
1.5
2.4
0.93


YDL024C
1.2
1.7
2.6
1.9
2.1
2.8
0.9
1.1
0.40


YDL095W
1.0
1.1
2.2
0.5
2.0
0.5
0.7
0.9
1.57


YDL245C
1.5
1.0
2.0
1.2
1.8
1.5
1.0
1.1
0.28


YDL246C
2.6
1.2
2.9
1.7
2.6
1.7
1.8
1.8
0.43


YDR001C
0.7
1.1
2.8
1.0
4.4
1.9
1.1
1.6
0.75


YDR058C
1.7
1.2
2.5
1.8
1.2
1.9
1.1
1.6
0.56


YDR072C
0.7
0.9
1.9
0.6
0.4
0.7
1.9
1.9
2.81


YDR127W
1.3
0.8
1.7
1.0
1.3
0.6
0.9
0.7
0.78


YDR261C
1.2
1.0
1.9
0.9
2.3
0.6
0.9
0.8
0.68


YDR272W
2.1
1.2
2.4
1.4
1.1
2.1
1.4
2.3
1.51


YDR497C
0.7
0.9
2.7
0.6
10.1

1.6
1.8
1.45


YDR516C
2.8
1.1
2.5
0.7
0.4
1.7
1.1
1.2
1.66


YER053C
2.4
1.7
4.1
1.3
1.1
2.8
1.2
2.3
1.83


YER096W
1.1
0.9
2.3
3.1
1.4
2.0
1.0
1.2
0.22


YER178W
2.5
1.3
2.4
0.9
1.8
1.0
1.1
0.9
2.18


YFL030W
5.4
1.2
2.2
0.8
1.1
0.6
1.0
0.8
0.50


YFL031W
1.2
1.0
2.6
0.4
2.7
0.9
1.2
1.1
3.16


YFR047C
2.3
1.7
2.7
1.9
0.6
3.6
1.5
1.6
1.57


YGL248W
1.0
0.8
2.0
1.3
1.8
2.9
1.1
1.2
0.22


YGR037C
1.4
1.5
2.7
1.5
1.5
2.6
1.4
2.0
3.40


YGR055W
1.5
0.9
1.9
1.2
2.1
0.6
0.7
0.7
1.42


YGR194C
0.7
0.8
2.2
1.0
0.6
2.6
1.1
2.0
0.63


YGR256W
2.7
1.5
3.9
1.1
2.7
5.3
1.1
0.8
0.94


YHR111W
1.9
0.9
2.2
1.7
1.1
1.3
1.1
1.2
0.44


YHR174W
1.4
1.5
3.6
0.6
2.0
1.1
1.0
1.2
7.34


YHR176W
1.2
1.2
1.9
1.3
1.5
1.8
1.4
1.6
0.27


YIL045W
1.2
1.5
2.0
1.6
0.6
2.9
1.1
1.8
0.37


YIL107C
0.9
1.1
1.9
1.6
1.0
2.7
1.2
2.0
0.58


YIL155C
1.3
1.4
2.0
1.3
1.4
3.8
1.1
1.4
0.51


YIR034C
3.0
1.4
2.6
1.2
1.9
1.3
1.0
1.0
0.92


YIR036C
2.8
1.2
1.9
1.2
1.1
4.0
1.5
1.3
0.64


YJL031C
1.9
1.3
2.6
3.0
2.0
1.9
1.2
1.9
1.02


YJL068C
3.2
1.7
2.7
1.5
0.5
2.6
1.4
1.5
0.95


YJL099W
0.9
1.0
2.4
1.8
1.4
1.7
1.2
1.6
0.55


YJL172W
1.4
1.1
3.1
0.9
1.2
0.5
1.8
1.8
0.62


YJL219W
2.3
1.1
4.0
1.1
2.6
1.4
1.6
1.2
0.91


YJR137C
2.0
1.4
2.1
1.2
1.0
1.3
0.9
0.8
0.46


YKL035W
2.1
1.0
2.0
0.6
1.0
1.5
1.0
1.9
2.54


YKL091C
1.7
1.3
2.0
1.5
1.1
4.6
1.4
2.0
0.83


YKL104C
2.2
1.6
2.2
0.8
3.3
0.6
1.0
1.1
1.25


YKL152C
1.7
1.5
2.7
1.0
1.8
2.0
1.1
1.7
3.28


YKL213C
1.3
0.9
2.1
0.9
1.1
1.5
1.4
1.6
0.77


YKL215C
0.5
1.0
2.6
1.0
0.9
0.8
0.8
0.9
0.38


YLL058W
2.0
1.0
2.3
0.8
1.9
1.1
1.4
1.3
0.39


YLR299W
1.7
1.0
2.9
1.3
1.5
0.9
1.3
1.4
0.57


YLR348C
1.3
0.9
1.9
1.0
2.4
1.1
1.1
1.0
0.64


YML054C
1.4
1.8
2.8
2.1
1.1
7.8
1.1
1.6
0.25


YML070W
1.5
1.3
3.3
1.3
0.9
2.6
1.2
1.3
1.03


YML100W
3.2
1.2
3.8
1.2
1.8
2.2
1.0
1.5
0.88


YMR008C
1.3
1.1
3.7
0.7
2.0
1.2
3.0
1.9
1.59


YMR020W
1.5
1.1
3.0
1.1
1.8
2.8
2.3
2.2
0.81


YMR105C
3.0
1.7
3.3
1.0
0.9
2.0
1.6
2.6
1.21


YMR271C
1.7
1.3
3.6
1.8
0.6
5.7
1.3
2.2
0.70


YNL012W
1.6
1.3
2.9
1.0
1.6
1.2
1.3
1.5
0.24


YNL045W
2.1
0.9
2.6
0.8
0.8
2.4
1.1
1.1
0.80


YNL104C
2.1
1.1
2.1
0.9
2.5
1.5
0.9
0.9
1.69


YNL231C
1.3
1.8
2.9
0.9
0.9
0.7
3.1
4.0
2.13


YNR019W
0.7
1.0
2.1
1.0
1.6
0.8
2.4
2.0
0.37


YNR033W
0.4
1.1
3.8
0.9
1.3
2.2
0.9
1.1
0.72


YNR059W
1.0
0.8
2.4
1.0
1.0
2.0
2.6
2.2
0.45


YOL126C
1.8
1.1
2.6
1.2
1.4
2.5
1.6
2.4
0.59


YOL153C
2.4
1.9
2.9
1.5
1.2
5.4
1.1
1.7
0.37


YOR099W
1.2
1.1
1.6
0.7
1.5
1.1
1.2
2.3
3.94


YOR130C
0.6
0.9
2.1
1.3
1.0
0.8
1.5
1.1
0.51


YOR336W
1.4
1.0
2.1
1.1
0.6
0.9
1.0
1.0
0.44


YOR347C
1.4
1.2
1.8
0.9
2.0
1.4
1.7
1.3
1.31


YPL017C
0.4
1.0
1.9
1.6
1.0
1.3
1.3
0.8
0.19


YPR026W
1.6
1.2
2.3
1.5
3.1
2.5
0.9
1.3
0.26


YAL012W
4.0
1.1
1.1
0.9
3.1
1.0
0.9
0.8
0.96


YBR029C
0.7
1.3
1.7
0.9
3.5
0.9
0.6
0.8
1.56


YBR222C
1.3
0.9
1.6
0.5
4.3
2.1
0.8
0.9
0.52


YCL009C
1.5
1.7
1.6
0.7
6.5
0.9
1.1
0.8
0.68


YCL064C
1.8
0.7
1.6
0.8
21.4
1.0
0.3
0.3
1.42


YCR098C
1.3
1.3
1.4
1.1
11.0
0.8
1.7
1.6
0.22


YDR502C
1.3
1.3
1.2
0.8
8.2
1.0
0.9
0.9
2.75


YER026C
0.9
1.7
1.9
1.1
4.0
1.4
1.7
3.2
4.48


YHR137W
0.6
0.6
0.6
0.8
2.8
0.4
0.8
1.3
1.40


YMR189W
8.2
0.6
0.9
1.6
5.6
0.9
1.0
0.8
0.88


YNL106C
0.9
0.8
0.9
1.1
3.3
1.2
1.1
0.9
0.37


YNL169C
0.8
1.0
1.7
0.9
3.4
0.8
1.1
1.3
1.05


YNL322C
0.6
0.7
0.8
1.2
3.7
0.9
0.9
1.0
0.75


YAL038W
1.0
1.2
1.8
0.5
3.1
0.9
1.0
1.0
7.02


YBR023C
0.9
0.8
0.5
0.8
2.8
0.7
0.7
0.9
0.93


YCR048W
1.2
0.9
1.3
0.9
3.1
1.1
1.2
0.8
0.29


YDR380W
0.4
0.4
0.4
0.6
2.4
0.2
0.8
0.8
1.04


YER069W
1.5
0.8
1.4
1.3
2.4
1.1
1.1
0.9
0.25


YGL022W
0.8
0.7
1.0
0.5
4.0
0.3
0.9
0.7
0.91


YGL126W
1.0
0.6


2.8

0.9
0.9
0.34


YGL209W
0.8
1.3
1.9
1.6
3.2
2.8
1.1
1.5
0.63


YGR282C
1.5
1.3
1.2
1.0
2.9
1.4
1.1
1.5
5.04


YIL154C
1.2
1.1
1.7
0.9
4.3
1.2
1.2
1.0
0.39


YJL088W
0.9
0.7
1.0
2.0
5.7
0.7
1.4
0.9
0.27


YJR148W
0.6
0.8
1.1
1.3
3.2
1.3
1.3
1.7
1.50


YLR180W
1.7
0.6
0.6
0.6
2.5
0.5
0.8
0.7
3.23


YLR273C
1.4
0.9
1.7
1.3
2.6
1.5
1.0
1.0
0.20


YLR300W
1.0
0.5
0.2
0.6
2.7
0.3
0.7
0.5
5.14


YLR307W
0.8
0.7
1.0
1.9
3.9
0.9
1.1
1.0
0.16


YMR296C
0.8
0.8
0.9
0.7
6.7
0.5
0.8
0.7
0.52


YOL058W
2.3
1.3
1.2
1.5
2.7
0.9
1.2
0.8
0.82


YBR183W
1.9
1.2
1.4
1.3
1.1
2.1
1.4
2.4
1.47


YDR019C
1.8
0.7
1.0
1.6
1.8
1.8
1.2
1.6
2.48


YIL167W
1.9
0.7
1.2
1.4
0.6
2.3
0.7
0.8
2.11


YKR039W
1.9
1.5
1.3
1.2
1.7
1.9
0.9
1.1
0.40


YNL037C
1.4
1.3
1.9
1.3
0.9
1.4
0.9
1.3
2.05


YNR002C
1.6
1.2
2.1
1.2
1.0
2.4
1.5
2.1
0.29


YOL143C
2.0
1.2
1.2
0.7
1.0
2.2
1.8
1.4
2.30


YOR136W
1.4
1.2
1.5
0.9
1.2
1.3
0.8
1.3
3.20


YAL044C
1.4
0.6
1.1
1.4
0.7
1.0
1.4
1.8
4.07


YAL054C
1.3
1.0
1.8
1.3
0.9
2.5
1.5
1.4
0.24


YAR071W
1.1
2.0
0.3
1.1
1.1
0.3
0.7
1.6
3.21


YBL001C
2.3
0.7
1.0
1.5
1.0
1.7
1.6
1.8
2.38


YBR014C
1.8
0.6
0.9
1.2
1.2
1.5
1.0
1.6
1.29


YBR035C
2.0
1.2
1.8
1.3
0.7
2.1
1.5
1.9
1.89


YBR068C
0.8
0.8
2.2
1.8
1.6
5.5
1.1
1.3
1.99


YBR111C
1.5
1.2
1.6
1.6
0.7
3.5
1.4
2.4
3.20


YCR037C
0.8
0.7
1.3
0.8
1.0
1.1
1.4
0.9
0.74


YDL022W
2.8
1.2
1.5
0.8
0.9
1.1
1.0
1.4
1.79


YDR009W
0.1
1.0
1.2
1.5
3.2
1.0
1.2
1.0
0.21


YDR410C
1.6
0.9
1.2
1.3
1.2
0.8
1.0
1.0
1.33


YDR487C
2.1
1.3
1.5
2.5
1.0
1.5
1.5
1.9
2.61


YEL011W
3.7
1.5
1.5
1.5
0.4
2.4
1.4
2.5
0.89


YFR015C
3.9
0.4
2.5
3.1
0.4
2.4
1.3
1.2
0.66


YGL001C
1.6
0.9
1.0
1.1
0.9
2.2
1.9
2.1
2.53


YGL104C
1.8
1.1
2.0
1.0
0.9
1.7
1.3
1.3
0.58


YGL154C
0.9
0.9
2.0
1.1
0.8
0.7
1.0
1.1
0.57


YGL253W
1.0
1.2
1.5
0.5
0.8
0.4
0.7
0.8
4.63


YGR060W
0.8
1.0
0.6
0.8
1.4
2.1
1.3
1.6
4.19


YHR037W
1.7
1.1
1.1
1.1
1.1
2.0
1.0
1.4
1.15


YHR092C
1.5
1.0
0.5
1.6
0.2
1.2
0.9
1.3
6.09


YHR190W
1.3
1.1
1.7
1.3
1.3
1.8
1.3
1.8
2.15


YIL033C
1.8
1.1
2.5
0.7
1.0
2.0
1.0
1.2
1.18


YIR035C
1.3
0.9
1.1
1.1
1.4
1.0
1.1
0.9
1.51


YJL132W
1.4
1.0
1.3
1.4
1.1
2.1
1.3
1.5
0.37


YJL196C
2.3
1.1
0.6
0.8
0.6
1.7
0.9
1.9
2.85


YJR142W
0.9
0.8
1.6
1.3
0.6
2.0
1.2
1.4
0.94


YKL067W
1.8
0.9
1.7
1.2
1.1
2.4
1.4
3.2
3.29


YLR142W
3.8
0.8
1.2
2.1
1.6
3.4
1.9
3.2
0.28


YML110C
1.7
1.1
1.8
1.4
1.3
2.3
1.1
1.6
2.01


YMR272C
0.8
1.2
1.2
0.8
1.1
1.5
1.3
1.4
1.66


YNL130C
1.5
0.9
1.9
1.0
2.5
0.7
0.7
1.2
1.18


YPR006C
2.4
1.1
1.8
1.2
0.7
1.6
1.8
2.1
0.46


YBR050C
1.1
1.0
1.3
1.3
0.5
1.7
1.5
1.8
0.41


YBR145W
1.1
1.0
2.0
2.2
1.2
3.6
1.7
2.0
2.17


YBR299W
2.4
1.2
0.7
1.4
0.6
3.9
1.0
1.1
0.32


YEL020C
1.3
0.8
1.2
1.0
1.4
2.1
1.2
1.3
0.31


YGL039W
1.1
1.3
1.5
0.9
1.5
1.5
0.6
1.0
1.09


YGL134W
1.1
0.9
0.7
1.1
0.5
1.7
0.9
1.3
0.53


YJR159W
2.2
1.5
2.1
2.0
2.3
5.2
1.7
2.3
0.30


YOL157C
1.2
1.2
1.4
1.2
1.1
3.5
1.4
1.3
0.41


YOR344C
0.6
1.3
1.8
0.6
0.7
0.6
1.3
1.3
2.11


YPL265W
1.8
0.9
1.1
1.1
1.2
2.0
0.5
0.4
1.42


YBR126C
1.1
1.3
2.1
0.7
1.0
1.7
1.5
1.3
1.96


YCR005C
2.1
0.5
0.7
0.8
0.7
0.7
1.6
1.7
2.38


YDR452W
1.5
0.9
1.4
1.2
1.3
1.3
1.9
2.2
1.54


YGR019W
1.1
1.2
2.1
1.3
2.2
2.4
1.3
2.0
0.79


YGR255C
2.0
1.3
2.5
0.9
1.0
1.1
1.1
1.1
0.81


YIL098C
1.4
0.8
1.3
1.9
0.7
2.0
1.2
1.6
0.75


YIL172C
1.0
1.4
2.0
1.3
1.4
2.8
1.1
1.2
0.42


YLR100W
0.9
1.1
1.6
1.1
0.6
1.9
1.5
2.1
1.88


YOR221C
1.1
0.8
1.0
1.1
1.0
1.4
0.9
1.2
0.39


YPL123C
1.9
1.0
2.2
1.6
1.4
2.6
1.6
3.2
0.71


YBR093C
3.1
2.0
0.2
1.3
2.7
0.4
0.8
1.9
3.33


YBR196C
2.3
1.0
1.4
0.5
1.9
1.1
0.8
1.0
6.60


YER023W
2.1
0.8
1.2
0.7
1.2
1.6
1.5
1.4
1.77


YFL055W
2.7
0.9
1.3
1.5
0.7
1.4
1.4
1.0
0.23


YIL124W
2.8
1.1
0.9
1.1
0.6
3.1
1.2
2.1
2.39


YMR318C
3.6
0.8
1.8
1.7
1.5
1.1
1.1
1.1
3.17


YBR067C
3.1
1.0
0.9
0.7
3.3
2.5
0.5
0.4
1.76


YBR115C
1.8
0.9
2.3
0.7
1.1
0.5
0.6
0.6
0.64


YDL131W
2.2
1.2
1.0
0.9
1.1
0.9
0.7
0.6
1.81


YDL168W
1.9
0.6
1.3
1.6
1.2
1.1
0.9
0.8
1.08


YDR216W
2.1
1.0
2.4
0.9
2.5
1.6
1.0
1.8
0.44


YDR253C
2.3
1.0
2.2
3.6
1.2
1.6
1.0
1.0
0.38


YDR513W
2.0
0.9
1.8
2.0
1.3
3.8
1.3
3.2
3.10


YER061C
2.2
0.7
0.9
1.0
0.8
1.8
1.2
1.2
0.84


YFL052W
2.3
0.8
1.0
1.6
0.4
1.0
1.1
0.9
0.32


YFL058W
2.4
1.2
1.2
1.0
1.7
0.7
1.1
0.9
0.40


YFR030W
2.4
2.4
4.1
1.3
1.7
1.6
1.3
0.9
0.30


YGL202W
2.4
0.9
1.1
0.8
2.2
0.6
1.3
0.9
1.70


YGR070W
1.8
0.6
1.4
1.0
2.6
2.3
1.2
1.3
0.40


YHL036W
2.3
1.2
1.5
1.2
0.9
1.1
1.0
1.0
0.60


YHR104W
2.6
1.0
1.2
1.5
1.6
1.3
1.9
1.9
1.57


YJL045W
2.3
1.1
1.6
1.2
3.4
2.4
0.9
0.9
0.42


YJL060W
1.6
1.5
2.1
1.7
1.4
1.5
1.2
1.1
0.95


YJL155C
2.4
1.0
6.6
1.2
1.2
2.3
1.8
3.1
0.60


YJR109C
1.5
1.4
3.1
0.9
1.3
0.5
1.1
0.6
0.84


YJR156C
3.0
1.1
1.6
2.4
3.0
2.3
0.8
1.1
0.24


YLR092W
3.1
1.0
1.8
1.4
0.9
1.2
1.0
1.1
0.24


YMR081C
2.5
1.1
0.7
1.8
0.2
3.0
1.9
3.0
0.62


YMR250W
4.3
1.2
2.6
1.1
2.0
5.0
1.2
3.0
0.84


YNL277W
3.2
1.3
1.8
1.5
0.6
1.3
0.9
0.7
0.27


YOR184W
2.7
0.7
0.6
0.7
1.0
0.9
1.2
1.2
3.19


YPR160W
4.4
2.1
2.2
1.1
1.4
5.3
1.0
2.9
1.42


YDL182W
2.0
1.4
1.5
0.8
0.7
1.1
0.6
0.6
2.31


YBR291C
1.1
0.9
1.0
1.7
0.5
1.5
0.9
1.3
1.19


YIL094C
1.8
1.0
0.7
1.0
0.5
0.9
0.9
1.0
2.26


YNR050C
1.5
1.0
1.1
0.6
0.3
1.4
0.6
0.7
2.13


YDL244W
1.2
1.2
2.0
2.0
2.9
1.5
1.1
1.0
0.25


YDR054C
1.9
1.0
2.5
1.1
1.6
1.4
0.8
1.4
1.18


YDR353W
1.4
0.8
0.7
1.6
1.3
1.0
0.9
1.3
3.20


YEL070W
1.1
1.1
1.1
2.1
3.2
1.9
0.9
1.0
0.27


YIL168W
1.9
0.8
0.9
1.5
1.2
1.2
1.0
1.1
0.39


YJL221C
0.8
1.1
1.4
1.1
1.1
3.3
1.1
1.4
0.41


YJR095W
0.6
0.7
0.8
1.3
0.8
0.8
1.3
0.9
0.23


YKL085W
1.8
0.8
1.5
1.0
0.5
1.7
0.9
1.3
2.16


YKL188C
1.1
1.2
1.2
2.1
1.4
2.7
1.1
1.5
0.27


YKL217W
1.6
0.8
1.2
1.2
2.2
3.0
1.7
3.3
0.29


YKR061W
1.1
0.9
0.9
1.6
0.9
0.8
1.5
1.6
0.70


YLR174W
1.3
1.3
1.8
1.7
0.8
4.6
0.9
1.2
0.41


YLR260W
0.6
0.8
1.9
1.2
1.0
1.0
1.1
1.2
0.44


YNL009W
1.3
0.9
1.3
1.3
2.7
3.3
1.2
2.3
0.45


YNL117W
1.4
0.7
1.3
2.0
2.6
1.6
1.1
0.9
0.24


YNL183C
1.3
1.1
2.3
1.1
1.1
1.2
0.8
1.0
0.47


YNR073C
2.2
1.1
1.2
2.3
1.7
1.6
1.0
0.9
0.18


YPL161C
1.0
1.0
1.2
1.1
0.8
1.4
1.3
1.3
0.41


YAL061W
4.1
1.1
1.4
0.7
0.6
1.1
1.4
1.2
0.88


YAL067C
1.2
1.0
1.1
1.3
2.4
1.6
1.0
1.0
0.33


YBL033C
1.1
0.9
1.8
1.4
1.0
1.2
1.2
1.0
0.53


YBL086C
1.3
0.5
0.9
0.8
0.5
1.4
0.9
1.0
0.43


YBR117C
0.4
0.8
2.1
0.9
1.0
12.0
0.7
0.7
0.49


YBR213W
0.5
1.2
1.4
1.3
1.7
0.8
0.9
0.9
0.23


YCR036W
1.0
1.3
1.8
1.5
1.7
1.6
1.6
1.7
1.35


YDL132W
1.3
0.7
2.0
0.9
1.7
1.0
0.9
1.1
0.74


YER014W
0.9
1.1
1.5
1.2
2.3
0.8
1.0
0.9
0.43


YER042W
1.8
1.1
1.4
5.2
1.0
1.9
0.7
1.1
1.80


YER090W
1.8
1.3
1.2
1.2
1.5
0.8
1.1
0.9
0.97


YGL026C
3.4
1.3
1.8
0.9
2.4
0.7
1.5
0.8
0.87


YGL252C
0.9
0.9
1.2
1.0
1.3
1.2
1.0
1.3
0.91


YGL254W
1.1
1.2
2.4
1.3
1.1
1.4
0.8
1.2
0.53


YGR276C
0.9
1.0
1.8
1.0
0.8
1.3
0.9
1.1
0.97


YHR106W
1.4
0.7
1.0
1.2
0.9
2.4
1.3
1.1
1.73


YIL046W
1.2
1.0
1.7
1.1
1.3
1.8
9.0
5.8
0.68


YJL071W
1.3
1.1
1.0
1.0
1.5
1.2
0.9
0.9
0.41


YJR139C
1.5
1.0
1.5
1.4
0.7
1.2
1.0
1.3
4.47


YKR069W
2.0
1.4
1.4
1.7
1.1
1.8
1.0
1.0
0.25


YLL061W
1.7
0.7
0.9
1.3
1.4
1.0
0.6
0.7
0.33


YLR070C
0.4
0.7
2.0
1.3
0.5
2.1
1.0
0.9
0.31


YLR099C
1.2
0.9
0.8
0.7
0.9
0.7
0.7
0.5
0.92


YLR157C
1.9
1.2
1.8
1.1
1.1
2.1
1.6
2.1
1.70


YLR160C
1.6
1.2
2.0
1.2
1.0
2.0
1.6
2.2
1.59


YLR164W
3.2
0.7
1.0
1.5
0.7
11.0
1.5
1.2
0.31


YML042W
2.5
1.0
1.2
1.4
1.7
4.8
1.0
0.9
0.29


YOL049W
1.8
0.8
0.9
0.9
0.7
1.3
1.0
1.3
1.61


YOL064C
1.0
0.9
2.0
0.9
1.0
1.7
1.2
1.3
1.32


YOR377W
1.2
0.9
1.3
0.9
1.2
1.3
1.1
1.1
0.46


YPL031C
1.4
0.8
1.6
0.9
0.7
2.0
1.4
1.2
0.49


YPL113C
1.5
1.1
1.7
1.6
0.9
2.5
1.2
1.7
0.28


YPL274W
2.0
0.5
0.6
0.9
1.5
1.1
0.7
0.6
0.41


YPR048W
1.0
0.8
0.6
1.2
0.6
0.8
0.7
0.8
0.75


YBR001C
1.0
1.0
2.0
1.2
1.8
1.4
1.0
1.6
0.61


YBR018C
5.8
1.0
1.0
2.4
1.3
6.2
0.8
0.9
0.20


YBR204C
2.2
1.0
1.7
1.4
1.2
2.3
1.1
1.5
0.84


YBR241C
1.4
1.4
1.4
0.9
1.6
0.7
1.0
1.2
1.25


YCR105W
2.3
0.9
1.9
1.9
3.1
1.3
1.3
1.1
0.36


YDR287W
1.5
1.1
1.5
1.2
1.6
2.7
1.5
1.3
0.52


YDR294C
1.2
1.1
1.6
1.0
2.0
1.7
0.9
1.1
1.02


YER052C
1.1
0.9
2.1
0.7
1.2
0.2
0.8
0.4
1.54


YFL021W
1.3
0.9
1.5
1.1
1.3
1.0
0.8
0.5
0.40


YGL040C
0.9
0.6
1.6
1.3
0.7
1.5
0.7
1.0
1.77


YGL125W
1.6
1.0
1.4
1.0
1.9
1.2
1.2
1.1
0.27


YGR007W
0.9
0.8
1.4
1.8
1.9
1.3
1.1
1.4
0.74


YGR155W
1.3
1.0
1.4
0.7
0.5
1.0
0.5
0.6
4.15


YIL099W
0.9
0.9
1.4
1.6
5.5
1.2
1.0
1.1
0.18


YIL170W
1.7
0.7
1.9
1.1
2.3
1.8
1.6
1.5
0.48


YIR031C
1.2
0.8
1.0
1.2
0.8
0.7
0.9
0.8
0.44


YIR032C
1.4
1.0
1.4
1.6
0.6
1.6
0.9
1.1
0.40


YJL128C
0.6
1.0
1.7
0.8
1.2
0.9
1.0
1.0
0.42


YJR090C
0.4
0.8
2.2
1.0
1.6
0.8
1.1
1.0
0.60


YJR103W
1.1
0.6
0.7
0.7
3.2
2.3
0.9
1.0
0.74


YJR153W
2.0
0.7
1.3
1.7
2.9
1.6
0.8
1.0
0.18


YKL192C
1.1
1.2
1.7
1.5
1.2
2.1
1.0
0.8
1.57


YLR025W
1.1
0.9
1.0
1.7
1.5
2.2
1.2
1.3
1.15


YML051W
1.4
0.7
1.2
1.1
1.4
1.1
0.7
1.0
0.57


YML099C
1.6
1.1
1.3
0.9
1.0
1.6
0.7
0.8
0.48


YMR056C
1.6
0.9
0.9
1.1
0.7
2.4
1.0
1.1
0.72


YNL257C
1.0
1.1
1.7
0.8
1.0
1.4
0.9
1.3
0.63


YNL264C
1.0
1.1
1.5
1.2
1.1
1.3
0.7
1.1
0.48


YNR071C
1.3
0.6
1.7
1.1
1.8
1.0
1.0
0.9
0.16


YOL065C
1.0
0.8
1.3
1.1
0.7
2.6
1.1
1.5
0.43


YOL067C
1.3
0.7
1.7
0.7
1.2
1.1
1.4
0.9
0.55


YPL147W
1.3
0.9
1.5
1.0
2.4
2.5
1.5
3.6
0.33


YDR043C
1.3
0.9
0.7
1.8
1.2
1.4
1.9
1.2
0.66


YGR180C
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90


YJL026W
1.3
1.0
1.2
1.0
1.1
1.6
1.4
2.1
3.74


YGR087C
0.8
1.2
1.2
0.7
3.5
0.6
1.0
0.6
1.88


YGL256W
1.0
0.9
0.8
0.9
1.0
0.7
0.7
0.8
0.90


YAL039C
1.1
1.4
1.6
1.2
3.3
2.2
1.4
1.1
0.39


YJR107W
1.3
1.1
1.7
1.4
1.1
1.1
1.4
1.3
0.41


YNL142W
0.9
1.2
0.9
0.8
0.3
1.0
1.0
0.9
0.44


YDL210W
0.6
0.8
1.2
1.1
1.9
0.9
1.1
0.9
0.20


YGL055W
0.9
1.3
0.2
0.7
0.5
3.0
1.0
1.5
5.60


YCL025C
1.0
1.1
0.5
0.7
0.8
0.6
0.6
0.6
1.98


YBR132C
1.9
1.0
1.4
1.1
1.5
1.3
1.1
1.3
0.43


YHL018W
1.2
0.7
0.8
1.0
0.9
0.9
1.0
0.9
0.37


YPL038W
1.1
0.6
0.6
0.9
0.6
0.8
0.9
0.9
0.64


YKR053C
0.5
0.7
0.7
1.3
0.3
0.9
2.8
2.4
0.35


YNL256W
0.6
0.6
1.3
0.7
0.9
0.4
0.6
0.6
1.09


YLR377C
0.6
0.6
1.2
2.9
0.8
2.7
0.9
1.4
0.14


YBR253W
1.1
1.0
0.8
1.2
0.9
1.3
1.3
1.1
0.96


YBL030C
1.1
0.9
0.5
0.8
1.8
1.0
1.0
1.1
3.12


YBR221C
1.2
1.3
1.7
0.8
1.1
1.5
0.9
1.0
3.62


YDR342C
2.9
1.0
0.6
0.9
0.5
2.4
1.0
2.2
5.23


YDR343C
2.3
1.0
0.8
0.8
0.5
2.8
1.1
2.3
5.81


YEL034W
1.1
0.9
0.8
0.9
0.8
0.9
0.9
0.9
5.44


YHR094C
0.6
0.9
0.7
0.6
2.7
0.9
1.4
1.4
4.82


YIL162W
2.8
2.0
1.0
1.0
1.5
1.7
0.9
1.4
1.22


YJR105W
1.0
0.8
0.8
0.5
1.2
0.7
1.1
0.9
3.75


YLR134W
1.1
1.2
1.5
0.6
1.7
0.5
0.6
0.8
3.47


YLR258W
1.2
0.9
1.4
1.2
0.6
1.7
1.0
2.0
1.36


YML058W
3.3
0.9
1.4
1.1
2.5
1.3
1.3
1.5
2.14


YMR083W
1.6
0.7
0.9
0.8
1.3
1.3
0.9
1.1
2.52


YOR178C
4.1
1.7
1.0
1.0
1.1
1.7
1.0
1.5
0.56


YPL028W
1.2
1.4
0.9
0.8
0.6
2.2
1.4
1.8
4.35


YPR113W
2.0
0.7
0.7
1.3
1.0
2.3
1.2
1.9
2.85


YPR183W
2.5
1.2
1.6
0.7
0.9
0.8
1.2
1.0
1.17


YBR011C
1.7
1.1
1.5
0.9
2.1
1.7
0.8
1.1
3.68


YCR034W
0.8
0.5
0.2
0.6
0.9
0.3
0.9
0.7
3.77


YDR050C
2.0
1.4
2.0
1.2
1.9
1.3
1.1
2.3
6.26


YDR178W
2.0
1.3
1.5
1.5
0.7
3.0
1.2
2.3
2.27


YDR284C
1.3
0.9
1.2
1.3
0.9
1.7
1.5
1.5
1.44


YDR345C
1.5
1.4
1.2
0.8
0.8
1.0
1.3
1.8
5.65


YDR400W
1.3
0.4
0.7
0.9
0.8
1.1
1.1
0.8
0.56


YEL063C
0.8
1.1
1.1
0.8
1.3
1.0
0.7
0.7
1.12


YER081W
1.1
1.0
0.6
1.6
0.5
0.8
1.1
1.7
2.31


YER120W
1.1
1.3
1.0
0.9
1.5
1.0
1.2
1.0
1.52


YFL011W
2.1
0.9
0.8
0.8
1.7
1.2
0.8
1.0
1.25


YGL012W
0.6
0.6
0.3
0.8
0.6
1.2
0.9
1.1
4.88


YGR191W
1.6
0.7
1.0
0.7
1.5
0.7
0.8
0.8
1.58


YGR204W
2.1
1.0
1.3
0.5
1.6
0.6
1.0
0.7
1.49


YHR025W
2.1
0.9
0.7
0.6
2.1
0.5
1.0
0.6
0.68


YHR123W
1.2
0.7
1.5
0.8
2.3
0.5
1.1
1.0
0.85


YJL121C
1.1
0.6
0.7
0.9
1.0
0.6
1.1
1.0
1.00


YJR077C
1.6
1.0
0.9
0.7
1.5
0.7
1.0
0.8
1.79


YJR143C
1.3
0.6
0.3
0.6
1.1
0.5
0.7
0.8
3.24


YKL060C
2.1
1.3
1.2
0.8
1.6
1.5
1.2
1.7
6.01


YKL148C
1.5
0.8
0.8
0.8
0.6
1.1
0.8
1.0
0.54


YKL157W
1.5
1.0
2.3
0.8
1.2
1.7
1.2
1.5
1.22


YLR044C
1.1
1.4
1.7
0.5
2.2
0.6
0.9
0.9
5.16


YLR056W
0.8
0.9
0.2
0.7
0.9
2.1
1.1
1.1
3.61


YLR058C
2.6
0.4
0.3
0.7
1.5
0.4
0.8
0.8
2.71


YLR081W
2.6
1.0
0.6
1.0
0.7
1.2
0.7
0.9
1.46


YLR089C
1.7
0.6
1.0
0.7
1.7
1.4
1.2
1.3
1.27


YLR284C
1.5
0.6
0.8
1.3
1.0
4.5
2.9
8.1
0.84


YLR304C
1.6
1.0
0.5
0.7
1.6
1.8
0.5
0.7
2.39


YLR354C
1.7
1.2
1.0
0.9
2.4
1.3
1.0
1.5
4.53


YLR372W
0.9
0.6
0.1
0.6
0.7
0.2
0.5
0.6
4.46


YML022W
1.2
0.6
0.2
0.9
0.6
0.6
0.5
0.7
4.93


YMR011W
1.5
0.8
0.4
0.6
0.6
1.2
1.3
1.6
4.95


YMR015C
1.0
0.9
0.4
0.8
1.2
1.5
1.0
1.0
2.51


YMR205C
1.0
1.1
1.3
0.5
0.9
0.9
0.6
0.5
4.75


YMR261C
0.8
0.9
1.6
0.6
0.8
1.6
0.7
1.1
0.78


YMR323W
2.5
1.2
1.8
1.2
37.3
0.6
1.1
0.6
1.04


YOL086C
2.6
1.3
1.7
0.6
1.6
1.4
1.1
1.3
4.19


YOL156W
1.1
0.9
1.7
0.9
1.9
0.9
0.9
0.9
0.53


YOR002W
1.2
0.5
0.6
0.9
1.5
0.8
0.9
1.1
1.49


YOR085W
1.1
0.8
1.0
0.7
1.8
0.8
0.9
0.9
1.86


YOR108W
1.4
0.7
1.3
0.9
0.7
1.0
1.1
1.1
1.07


YOR128C
0.8
0.5
0.4
0.7
1.6
0.5
1.2
1.2
2.14


YOR142W
1.5
0.8
1.4
0.8
1.1
0.8
0.9
1.0
1.31


YOR176W
1.4
1.3
1.5
0.8
0.8
1.4
1.2
2.1
1.23


YPL057C
1.6
1.0
1.3
0.7
1.1
2.5
2.2
2.0
2.08


YPL135W
1.3
1.1
1.2
1.1
1.5
1.2
1.5
1.7
1.50


YCR010C
1.1
0.8
1.0
1.2
1.2
2.8
1.9
1.5
0.26


YBR003W
1.3
0.8
1.2
0.8
0.7
2.0
1.1
1.3
1.06


YBR020W
1.0
0.8
1.1
1.0
1.3
0.7
0.8
0.9
0.27


YDR123C
0.6
0.5
0.9
0.7
1.2
0.8
1.3
1.0
0.30


YDR277C
1.2
0.9
1.2
1.3
0.4
2.3
1.2
1.7
0.89


YDR408C
1.7
0.6
0.5
0.9
1.0
1.0
1.1
1.1
2.16


YDR483W
1.4
0.8
1.3
0.8
1.5
1.2
1.2
1.4
3.24


YGL115W
1.0
0.9
0.7
1.2
0.7
1.7
0.8
1.2
2.46


YGR096W
0.8
0.8
1.1
1.2
0.9
0.8
0.8
1.0
0.49


YGR288W
1.3
0.9
1.3
1.1
0.8
1.7
1.2
1.3
0.41


YHR210C
1.5
0.5
0.4
1.0
0.5
1.5
1.4
1.2
0.33


YIL006W
1.0
0.9
0.8
1.0
1.5
1.7
0.8
0.9
0.28


YKR034W
0.0
0.7
1.2
1.1
1.7
0.6
0.8
1.0
0.26


YLR006C
1.5
0.7
0.8
1.0
0.9
0.8
1.6
1.0
0.40


YNL025C
1.1
0.8
1.3
1.2
1.4
2.9
0.7
1.3
0.37


YOL116W
1.0
0.6
0.8
0.9
0.7
1.9
1.1
1.4
0.47


YOR103C
1.0
1.2
0.8
1.2
1.4
1.3
1.1
1.5
2.84


YOR251C
1.0
0.9
1.0
1.1
0.6
1.2
0.9
1.3
1.34


YOR348C
1.1
0.7
1.1
1.2
1.6
1.7
0.9
0.9
0.18


YPL148C
3.5
0.7
0.6
1.6
0.6
1.6
1.0
1.1
0.48


YGL205W
0.4
1.1
1.0
1.0
2.0
4.1
3.9
9.1
0.24


YNL192W
1.1
1.1
2.7
0.7
2.1
0.8
2.3
2.8
1.31


YOL108C
1.1
1.0
1.3
0.9
1.5
1.8
1.5
2.7
0.87


YPR165W
1.0
0.8
1.0
1.0
0.9
1.0
2.3
2.7
3.64


YDR073W
1.0
0.8
0.6
1.2
0.8
1.6
1.8
2.3
1.27


YER015W
1.0
0.9
0.8
1.1
0.8
3.0
1.6
2.6
0.41


YJL167W
1.2
1.3
0.9
0.9
1.6
1.4
1.4
2.1
2.94


YJL216C
1.1
1.0
1.1
1.1
1.2
1.5
1.2
2.0
0.25


YKR009C
1.2
1.0
1.8
1.0
1.0
4.6
1.9
2.5
0.27


YOR180C
0.6
0.8
0.9
1.0
1.1
2.4
0.9
2.3
0.55


YBR036C
1.5
1.0
1.9
0.8
1.5
1.6
2.1
1.8
2.05


YDR297W
1.4
1.0
0.8
0.9
1.4
1.4
1.9
1.9
1.73


YDR387C
2.0
0.9
1.3
0.9
1.4
2.7
1.2
1.1
0.86


YOL096C
1.2
1.2
1.4
1.4
1.0
2.3
1.2
1.2
0.64


YPR184W
3.6
1.4
2.5
1.3
1.5
3.1
1.0
1.7
0.37


YBR298C
1.5
1.1
0.8
0.9
0.2
2.1
0.9
0.8
0.88


YDL078C
1.7
0.8
1.0
0.8
0.5
2.2
1.1
2.0
1.65


YDL215C
0.8
0.8
1.5
1.0
1.1
2.2
1.1
1.6
0.91


YGL035C
1.3
0.9
1.1
1.1
1.0
2.3
0.9
1.2
0.61


YGR287C
1.5
1.1
1.7
1.1
2.3
3.0
1.0
1.1
0.38


YJL070C
1.3
1.0
1.8
1.3
3.5
2.2
1.1
1.2
0.34


YLR351C
1.1
0.9
0.9
1.4
1.2
2.0
1.3
1.8
1.75


YLR375W
1.6
0.9
1.6
0.9
1.3
2.2
1.0
1.0
1.05


YMR267W
1.0
0.8
0.7
1.0
0.9
2.6
0.9
1.3
0.94


YMR278W
1.1
1.0
2.5
0.8
1.8
2.5
1.0
1.5
0.62


YMR293C
0.4
0.9
0.8
1.3
0.7
2.2
0.8
1.0
0.37


YNR072W
1.4
1.0
1.5
1.0
1.8
2.1
1.3
1.0
0.26


YOR363C
1.2
0.9
1.3
0.9
1.1
2.1
1.3
1.8
0.40










[0039]

9





TABLE 8








Detoxification protein genes
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YDR453C
1.1
2.7
4.4
3.0
0.7
1.7
1.0
1.3
4.5
6.1


YLL060C
12.5
4.2
2.3
2.6
0.9
1.4
2.0
5.8
13.0
23.2


YBL064C
2.6
2.8
3.9
1.7
0.8
5.2
2.5
2.4
4.5
3.8


YBR008C
3.0
2.4
4.9
0.7
0.9
1.0
0.9
2.8
54.6
21.1


YOR153W
1.6
0.9
5.1
1.1
1.0
7.4
2.6
0.5
3.2
1.2


YHL047C
0.6
4.4
1.0
1.0
1.2
8.4
16.8
1.5
1.2
11.9


YCL035C
2.0
2.3
1.5
1.7
1.5
5.1
2.7
1.4
1.9
2.3


YGR197C
1.1
2.4
2.5
1.0
0.7
0.5
1.3
0.8
16.7
3.2


YHR055C
4.4
1.8
0.8
1.2
2.7
1.6
1.1
2.1
3.9
3.3


YNL239W
1.0
2.4
2.4
1.2
1.2
1.8
2.1
1.3
2.5
6.0


YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4


YBR293W
1.9
3.1
1.0
1.8
0.8
0.9
0.9
0.9
5.5
2.4


YDL100C
1.0
1.2
1.1
0.8
1.0
2.1
1.6
1.7
5.4
3.2


YER185W
2.0
3.1
2.1
7.0
1.6
1.2
1.1
1.0
2.9
1.2


YGL013C
0.9
1.2
0.8
0.7
1.1
2.3
0.9
1.4
3.0
1.5


YHR053C
3.5
2.1
0.7
1.1
2.9
1.3
1.2
2.2
4.5
2.9


YIR038C
1.3
3.5
4.6
2.0
0.7
2.5
2.0
1.3
4.6
4.5


YKL026C
2.7
2.0
1.2
4.9
1.0
1.8
2.5
1.8
7.5
3.0


YLL028W
0.6
0.9
4.6
0.5
0.9
1.7
1.0
0.7
1.2
2.3


YOR273C
0.7
1.0
1.7
1.0
1.1
0.4
0.4
0.6
0.6
0.5


YGR138C
1.1
1.6
1.0
1.2
0.8
0.8
0.7
1.0
0.5
1.0


YOR247W
1.7
0.6
3.6
1.4
0.6
0.2
0.5
0.7
0.1
0.4


YPL163C
0.6
0.7
1.4
0.9
0.6
0.6
0.4
0.5
0.1
0.4


YHL040C
1.6
4.4
1.5
0.4
1.1
7.3
4.0
1.5
1.1
11.3


YEL065W
0.3
3.8
1.2
0.4
1.4
2.3
4.3
0.9
0.1
4.9


YIR002C
0.8
1.1
0.5
0.6
1.2
2.2
1.3
1.2
1.7
1.4


YNL259C
1.6
4.5
1.1
1.2
1.1
3.9
3.8
1.5
1.6
2.1


YBR145W
1.5
0.7
2.8
0.9
1.1
11.5
58.8
1.0
0.1
1.1


YLR043C
1.4
1.4
2.0
1.8
2.0
1.4
2.6
1.1
2.8
2.5


YGR209C
1.6
3.1
3.5
1.5
1.9
1.9
1.7
1.6
2.4
6.3


YDL168W
2.3
2.0
2.1
0.9
1.2
1.4
1.1
1.7
8.2
4.7


YDR513W
2.2
2.5
2.3
2.6
0.9
2.1
1.6
1.6
4.6
3.1


YGR088W
1.3
1.2
7.7
2.4
1.0
1.3
0.8
0.8
1.5
3.2


YHR048W
2.5
1.4
1.4
1.7
1.0
0.8
0.8
1.9
4.5
2.7


YJL101C
2.1
1.9
2.1
1.2
1.4
1.0
1.0
1.3
3.1
3.6


YML116W
4.1
1.3
1.5
1.4
1.2
0.9
1.4
2.2
1.4
3.1


YMR038C
1.9
1.7
1.8
0.8
1.5
1.0
1.1
1.9
2.4
2.6


YBR244W
0.6
1.4
2.0
0.9
1.7
1.0
0.6
1.0
1.4
3.0


YCL069W
0.9
15.7
0.9
0.8
0.9

1.4
1.3
1.2
6.9


YKR105C
0.8
0.9
0.9
1.5
1.0
1.2
1.0
1.3
1.0
5.2


YOL158C
0.7
4.0
2.4
0.9
1.2
2.0
1.6
0.7
1.7
6.1


YDR256C
0.8
1.4
0.7
1.3
1.2
0.5
0.6
0.8
5.2
2.0


YGL254W
1.2
1.1
0.8
0.6
1.1
0.7
1.3
1.4
3.1
1.8


YKL064W
0.6
0.9
0.4
0.8
1.2
1.5
1.1
0.9
2.4
1.6


YLL057C
2.2
59.9
1.8
0.9
1.1
1.0
1.6
1.4
121.8
2.9


YPR200C
47.7
1.7
0.8
5.0
1.6
0.8
1.3
1.4
4.7
3.8


YJR104C
1.4
1.8
2.9
1.2
1.5
1.4
1.1
1.5
1.9
2.8


YKR106W
1.3
0.8
2.1
1.4
1.2
1.6
0.9
1.3
10.5
7.4


YOR031W
2.6
1.7
1.3
3.4
1.4
0.9
1.3
0.9
0.7
1.3


YHR008C
1.3
6.9
4.8
1.8
0.6
1.0
0.7
0.9
1.7
2.4


YML028W
1.0
2.2
4.4
1.3
1.6
1.2
0.8
0.8
0.8
1.8


YEL027W
1.2
0.6
3.4
1.1
1.0
1.1
0.8
0.9
0.9
1.1


YKR066C
0.9
1.4
5.5
0.7
1.0
0.9
0.5
0.7
0.7
2.4


YDR538W
0.9
1.1
2.4
1.2
1.0
1.0
1.2
1.0
0.3
0.8


YMR015C
0.7
0.7
1.9
0.9
1.7
1.3
0.4
0.7
0.1
0.3


YOR251C
1.1
1.0
1.3
1.8
0.8
0.9
1.0
1.1
0.8
0.8


YLR046C
0.7
1.7
0.9
0.8
1.0
3.8
1.5
0.5
1.0
1.4


YGR224W
0.9
1.2
1.2
1.2
1.4
0.8
0.4
0.6
0.9
0.9


YFL050C
0.7
1.0
1.1
2.2
1.0
0.9
0.8
0.9
0.5
1.6


YCR083W
1.1
2.8
1.5
1.8
1.6
2.4
1.8
1.5
1.8
1.8











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YDR453C
2.3
0.9
1.4
3.8
2.3
5.6
1.0
1.5
1.53


YLL060C
14.1
1.1
1.8
10.6
1.5
3.6
1.9
2.3
0.57


YBL064C
2.9
1.7
4.1
5.0
1.3
5.0
1.2
2.3
1.67


YBR008C
9.4
0.8
2.0
4.1
0.8
3.1
2.0
1.2
0.37


YOR153W
1.0
4.0
11.8
0.3
3.6
1.6
2.5
3.1
1.91


YHL047C
1.0
2.6
3.8
0.5
1.1
2.3
1.2
1.2
0.74


YCL035C
2.1
1.5
2.8
2.5
1.9
5.5
2.6
4.2
1.74


YGR197C
1.1
1.2
2.4
1.5
1.0
1.5
1.7
1.9
0.37


YHR055C
1.8
1.2
3.0
1.5
0.5
0.8
0.9
0.6
3.96


YNL239W
1.9
1.5
3.6
1.3
1.7
1.5
1.1
1.4
0.68


YNL241C
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68


YBR293W
1.1
1.0
3.0
1.4
3.1
1.6
1.0
0.9
0.94


YDL100C
2.8
1.5
2.5
1.4
1.0
1.3
1.2
1.4
2.60


YER185W
1.6
1.1
2.1
1.6
1.7
0.6
2.6
1.1
0.26


YGL013C
0.9
1.0
2.3
0.8
1.0
0.9
1.1
1.0
0.43


YHR053C
1.4
1.1
1.9
1.5
0.3
0.7
1.0
0.5
3.99


YIR038C
3.4
1.1
2.5
2.5
1.2
6.0
2.8
2.0
1.11


YKL026C
3.0
1.0
2.3
1.8
0.8
6.6
1.6
3.3
0.61


YLL028W
0.7
1.3
4.1
0.7
3.1
0.6
1.2
1.2
1.02


YOR273C
1.5
0.8
2.6
0.5
0.8
0.6
3.2
3.1
1.20


YGR138C
0.7
0.6
0.6
0.9
4.5
0.7
0.7
0.7
1.24


YOR247W
2.9
0.6
0.3
0.4
7.3
0.2
1.2
0.9
2.23


YPL163C
0.5
0.9
0.4
0.6
5.3
0.6
1.4
1.4
1.05


YHL040C
1.7
2.0
2.0
1.1
3.4
1.0
1.4
1.0
0.69


YEL065W
0.6
1.7
0.8
0.4
2.2
2.6
0.7
0.6
2.10


YIR002C
0.8
1.3
1.2
1.1
1.1
1.4
1.1
1.2
0.58


YNL259C
1.6
0.7
1.1
1.4
0.7
1.7
2.6
2.4
1.22


YBR145W
1.1
1.0
2.0
2.2
1.2
3.6
1.7
2.0
2.17


YLR043C
1.4
0.8
2.0
2.1
0.5
1.8
1.5
2.2
2.12


YGR209C
3.1
0.9
1.4
5.0
1.3
1.9
1.3
2.4
3.17


YDL168W
1.9
0.6
1.3
1.6
1.2
1.1
0.9
0.8
1.08


YDR513W
2.0
0.9
1.8
2.0
1.3
3.8
1.3
3.2
3.10


YGR088W
3.9
1.1
1.2
1.3
0.7
5.6
0.9
2.0
0.75


YHR048W
2.0
0.9
1.1
1.7
0.9
1.4
0.7
0.9
0.26


YJL101C
2.7
0.7
1.0
1.0
0.5
1.3
0.9
1.0
1.13


YML116W
4.3
0.5
0.8
2.0
1.9
1.0
1.0
1.0
0.94


YMR038C
2.7
0.9
1.7
1.1
0.6
1.5
1.2
1.3
1.76


YBR244W
1.5
0.5
0.4
3.7
0.4
0.7
1.2
1.2
3.42


YCL069W
1.0
0.9
0.8
1.3
1.4
0.9
1.0
1.0
0.25


YKR105C
0.0
0.8
2.5
1.2
1.5
0.7
0.8
1.0
0.26


YOL158C
0.7
0.9
1.4
1.0
0.9
1.2
1.4
1.7
1.30


YDR256C
1.4
0.8
1.1
1.6
1.0
4.3
1.0
2.0
0.30


YGL254W
1.1
1.2
2.4
1.3
1.1
1.4
0.8
1.2
0.53


YKL064W
0.7
0.7
1.6
1.1
0.7
1.4
1.3
1.3
0.60


YLL057C
1.3
0.7
1.4
1.1
1.4
0.9
3.0
1.3
0.19


YPR200C
2.0
0.4
0.6
2.0
0.7
1.2
1.1
1.0
0.27


YJR104C
2.6
0.9
0.9
2.0
1.3
2.9
0.9
1.1
3.50


YKR106W
1.8
0.8
1.4
1.7

2.8
0.9
0.8
0.16


YOR031W
1.2
0.8
1.8
1.5
1.4
6.2
1.7
2.4
0.52


YHR008C
2.1
0.7
1.2
1.6
1.7
2.2
0.9
1.0
1.04


YML028W
1.0
1.6
1.6
2.0
2.2
1.3
1.1
1.5
4.85


YEL027W
0.9
0.9
0.7
1.4
1.5
1.6
1.0
1.4
4.75


YKR066C
1.3
0.9
0.6
1.5
0.6
1.3
0.9
1.1
1.25


YDR538W
0.9
0.7
0.7
0.9
1.0
0.9
1.0
0.9
0.53


YMR015C
1.0
0.9
0.4
0.8
1.2
1.5
1.0
1.0
2.51


YOR251C
1.0
0.9
1.0
1.1
0.6
1.2
0.9
1.3
1.34


YLR046C
0.9
0.8
1.2
1.3
0.8
1.3
5.2
5.4
0.86


YGR224W
0.8
0.6
0.8
0.9
1.1
1.0
2.8
1.3
0.27


YFL050C
1.2
0.9
1.2
1.0
1.4
2.3
0.8
1.0
0.36


YCR083W
1.8
1.1
1.8
2.4
1.0
3.1
1.3
1.3
0.98










[0040]

10





TABLE 9








Genes belonging to other category
















yeast
The level of expressed mRNA in the presence of chemical substance/

















genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)




















YKR076W
5.0
2.6
3.5
2.2
1.0
4.7
4.9
6.2
43.4
43.1


YNL335W
1.2
0.7
1.5
2.3
1.5
1.6
1.3
1.7
1.6
5.3


YBR173C
1.1
2.4
3.4
1.6
0.7
1.3
1.6
1.2
6.0
5.1


YFL022C
0.8
0.9
1.5
0.6
0.7
0.9
0.3
0.8
0.5
0.5


YGL158W
1.1
2.8
1.9
12.9
1.0
0.4
1.3
1.3
−0.4
0.9


YHR139C
3.0
4.6
6.8
9.3
1.3
1.9
1.5
1.3
107.2
46.6


YGR213C
5.4
2.9
1.0
6.8
1.2
4.1
7.0
2.0
7.5
6.9


YKL165C
0.5
2.0
1.1
0.6
0.9
0.6
2.1
1.5
0.4
0.4


YBL005W-A
1.0
0.9
0.5
0.9
1.3
1.2
1.4
1.0
0.8
1.5


YBL041W
1.2
1.4
0.9
1.0
1.6
1.7
1.6
1.7
2.8
2.6


YBL078C
2.3
2.7
1.3
2.6
0.7
2.4
3.1
1.6
12.3
15.2


YCL020W
1.1
2.5
0.5
1.1
0.5
1.0
1.5
1.7
0.9
2.4


YDL007W
0.8
1.4
1.3
0.9
1.0
1.1
1.2
1.4
3.8
2.4


YDL097C
0.9
1.7
0.9
1.2
0.8
1.3
1.6
1.5
4.5
2.3


YDL126C
0.5
1.4
2.3
0.7
0.9
1.2
1.5
0.8
2.7
2.0


YER012W
1.4
1.2
1.2
1.0
1.9
2.4
2.4
1.8
6.7
2.7


YFR010W
1.1
1.1
0.8
1.2
0.9
1.3
1.4
1.6
4.3
3.4


YFR024C
0.8
25.0
2.3
1.1
0.7
1.4
3.0
0.9
5.3
4.1


YGL048C
1.0
1.3
0.7
1.3
1.8
1.5
2.0
1.5
2.4
2.1


YGL141W
0.8
1.2
1.1
0.7
1.4
3.0
1.7
0.8
4.5
1.9


YGL180W
1.3
1.3
1.7
0.6
1.2
1.1
2.4
1.2
7.2
3.7


YGR048W
0.7
2.7
1.4
1.3
1.0
1.0
1.9
1.4
4.4
3.1


YGR135W
1.0
1.0
1.0
1.1
1.6
1.5
2.2
1.8
1.5
2.3


YGR201C
1.7
11.9
2.4
2.0
0.8
3.1
2.6
1.6
5.4
3.5


YHL030W
0.5
0.8
1.0
0.7
0.7
1.9
0.9
0.8
2.7
2.5


YHR166C
0.9
1.1
1.0
0.7
1.0
1.8
1.5
1.0
2.6
1.2


YJR069C
0.8
0.8
0.9
0.6
0.9
1.2
1.3
0.9
0.7
0.6


YKL073W
0.6
1.4
0.5
0.6
1.2
0.5
2.1
1.6
1.3
1.1


YKL103C
1.6
4.1
2.5
2.1
0.9
2.7
2.8
1.6
8.3
9.9


YLR080W
1.0
1.4
1.2
1.7
1.1
2.5
2.8
1.3
2.3
1.5


YLR107W
1.2
0.9
0.5
1.2
1.7
2.3
1.6
1.1
1.8
1.2


YLR121C
1.7
1.7
1.1
1.2
1.0
1.6

1.3
2.2
2.0


YLR336C
0.6
0.8
0.7
0.4
0.9
0.8
1.8
1.0
−0.3
0.5


YLR370C
1.1
1.0
1.1
1.4
1.4
4.1
2.1
0.8
1.5
1.9


YLR423C
1.2
1.2
0.7
1.9
1.5
1.2
3.8
2.0
1.2
1.0


YML092C
1.1
3.1
2.4
1.1
0.9
1.9
1.2
1.2
6.4
4.0


YML130C
1.5
2.7
5.3
1.2
0.9
0.6
2.9
2.7
7.8
4.2


YMR214W
0.8
3.8
1.0
1.4
0.8
0.9
1.0
1.1
2.1
1.0


YMR297W
0.7
2.0
3.6
1.9
0.6
1.8
1.2
0.8
1.9
1.0


YNL036W
2.0
1.9
3.2
1.0
1.6
1.1
2.0
2.1
6.6
5.0


YOL005C
1.4
1.4
1.1
0.8
1.6
1.1
1.1
1.0
0.9
1.0


YOR134W
2.0
3.6
1.0
9.5
0.9
1.4
1.1
1.5
1.5
8.2


YOR362C
1.0
1.7
1.0
0.8
1.7
1.4
1.6
1.4
4.3
3.0


YAR009C
0.8
1.3
0.6
1.0
1.4
1.6
2.7
1.4
0.9
1.4


YBL101C
1.0
1.1
1.9
0.9
1.0
0.9
0.8
0.8
3.0
1.4


YBR046C
1.4
1.4
1.7
1.8
1.3
2.6
3.9
1.6
4.6
6.2


YBR139W
1.2
1.4
3.1
1.4
0.8
2.4
1.9
0.7
2.3
1.6


YBR170C
0.8
1.2
0.6
1.4
1.5
1.4
1.9
1.3
6.1
4.2


YBR177C
0.8
1.1
4.0
1.2
1.2
2.3
0.9
0.9
2.1
1.7


YBR212W
0.7
1.2
2.6
1.2
1.0
1.4
0.9
0.6
2.7
2.3


YBR239C
1.0
1.3
0.9
1.5
0.8
1.5
1.0
1.3
0.4
1.2


YCL033C
1.1
2.0
1.7
1.7
1.2
4.6
2.4
1.1
2.3
1.4


YCR062W
0.8
1.9
2.7
2.8
1.4
1.9
0.9
0.7
0.7
1.3


YCR067C
0.9
0.7
1.2
1.3
0.7
0.8
0.8
0.7
1.8
1.6


YDL020C
2.3
1.2
3.4
1.1
1.2
2.5
1.0
2.2
5.6
2.9


YDR168W
1.2
1.4
1.0
0.8
1.5
1.3
2.4
2.1
3.7
2.3


YDR169C
1.0
1.4
1.1
1.3
1.3
1.2
1.1
1.0
1.6
1.4


YDR188W
0.8
1.2
1.0
0.8
0.8
0.8
0.9
1.0
2.9
1.6


YDR264C
0.5
2.6
0.9
1.4
0.9
1.8
3.2
0.8
1.1
3.4


YDR304C
1.0
1.8
2.7
1.3
1.5
2.1
2.0
1.3
3.9
1.9


YDR403W
1.0
1.2
1.6
1.0
1.2
1.1
1.2
1.2
4.1
3.6


YDR427W
0.8
1.1
0.8
0.8
1.5
1.9
1.4
1.2
2.3
2.0


YEL012W
1.3
1.8
1.0
1.8
1.7
1.6
4.7
1.4
4.6
4.2


YER009W
1.3
0.6
2.4
1.2
1.2
2.0
2.8
1.0
0.7
1.0


YER021W
0.8
1.0
0.9
0.9
1.4
1.1
1.5
1.2
3.0
2.2


YER094C
1.0
1.3
0.9
1.1
1.9
1.1
1.8
1.3
2.3
1.7


YER177W
1.4
1.5
2.1
1.5
0.9
1.6
1.2
1.1
1.8
1.7


YFL029C
1.0
1.2
1.2
1.8
1.7
1.0
1.6
1.5
4.3
2.9


YFL038C
1.0
1.2
0.7
1.3
1.5
1.3
1.7
1.4
2.1
1.9


YFR004W
1.0
1.5
0.8
1.4
1.0
1.5
1.3
1.4
3.6
2.6


YFR050C
0.9
1.2
1.1
1.3
1.7
1.5
1.4
1.4
3.1
2.1


YGL011C
1.2
1.5
1.1
1.1
1.8
1.6
1.5
1.3
2.0
2.2


YGL094C
0.8
1.3
0.3
0.9
1.3
1.0
0.8
1.0
1.4
1.1


YGL150C
0.7
0.8
1.2
1.0
0.8
1.1
0.8
0.8
1.4
0.9


YGL207W
0.5
0.6
0.9
0.6
1.3
0.9
0.6
1.0
1.4
1.1


YGR232W
1.2
1.2
1.2
1.7
1.5
1.9
2.0
1.1
3.4
2.2


YGR248W
1.3
1.7
3.2
4.0
0.5
2.3
1.1
1.2
2.8
3.2


YGR253C
1.3
1.4
0.7
1.3
2.0
1.4
1.6
2.0
4.0
3.1


YHR027C
0.5
0.8
1.2
0.6
1.1
0.4
0.9
0.6
3.6
2.2


YHR161C
0.6
1.1
1.3
2.1
1.5
1.2
1.8
0.7
2.5
2.0


YHR169W
0.6
0.5
0.4
0.4
1.1
1.2
0.9
0.9
0.0
0.2


YIL010W
1.0
1.2
1.4
0.8
1.2
4.4
1.5
0.9
1.4
2.2


YIL034C
1.0
0.8
1.5
3.0
0.7
1.7
1.2
0.9
2.1
1.3


YIL142W
0.7
1.1
0.9
1.1
0.8
1.1
0.8
1.1
4.4
3.0


YIR039C
1.4
1.8
4.3
4.2
1.5
3.2
4.1
1.1
4.4
4.1


YJL001W
0.9
1.7
1.2
2.0

1.7
1.6
1.3
3.1
2.8


YJL035C
0.9
1.3
0.8
0.6
1.4
0.7
1.3
1.5
1.7
1.4


YJL053W
1.1
0.9
1.7
1.3
1.1
2.0
1.7
1.3
2.2
2.2


YJL164C
1.1
1.1
1.0
1.9
1.1
2.7
3.1
0.9
2.1
0.8


YJL210W
1.2
1.4
1.6
2.0
0.6
0.6
1.0
1.0
2.0
0.9


YJR117W
1.0
2.1
2.3
0.7
1.2
1.3
1.0
0.8
4.7
2.3


YKL007W
1.2
1.6
1.2
0.9
1.0
0.9
1.5
1.2
2.3
2.4


YKL117W
1.0
1.3
0.8
1.0
1.8
1.0
1.3
1.5
2.9
2.1


YKL193C
1.3
0.8
1.1
1.4
1.1
0.9
2.1
1.4
1.0
1.6


YLR120C
1.2
1.9
2.4
1.6
1.1
1.9
1.5
0.9
1.8
1.6


YLR136C
1.3
9.0
0.6
3.3
1.6
1.7
3.9
1.1
0.9
6.0


YLR178C
1.7
6.9
8.8
4.6
1.0
4.2
3.3
0.9
4.3
4.1


YLR327C
5.5
3.3
14.4
8.2
1.3
5.1
5.7
2.2
3.0
8.3


YLR356W
1.0
2.9
4.9
1.2
1.1
3.4
1.1
0.7
2.3
1.6


YLR362W
1.1
1.2
1.0
3.0
1.5
0.8
1.9
1.4
3.5
3.3


YLR429W
0.7
1.0
0.6
0.9
1.4
0.8
1.3
1.0
0.9
1.3


YMR004W
0.9
0.9
1.3
1.3
1.0
0.5
1.2
1.0
94.2
3.4


YMR219W
0.7
1.1
1.0
0.7
1.6
0.8

1.1
2.3
0.9


YMR275C
0.7
0.7
1.2
0.6
0.7
1.4
0.8
0.8
2.4
2.1


YMR314W

1.2
0.9
1.3

1.3
1.1
1.2
5.9
2.7


YNL006W
1.1
2.1
1.3
1.5
0.9
1.0
1.6
1.1
4.0
4.0


YNL007C
0.7
2.4
5.1
0.8
1.2
0.6
1.2
0.8
3.0
1.7


YNL093W
2.1
6.4
0.4
4.5
1.2
1.6
1.4
0.8
1.7
2.0


YNL333W
1.0
1.4
1.7
2.3
1.5
1.5
2.9
2.1
2.3
2.1


YNR010W
1.3
1.2
0.5
2.8
1.8
1.3
1.5
1.1
1.7
0.9


YNR069C
1.5
1.3
0.7
0.4
1.4
1.7
1.4
1.4
5.5
5.8


YOL164W
0.9
4.4
1.0
1.5
1.6
1.2
2.2
1.0
4.9
3.6


YOR036W
1.8
0.9
1.4
1.6
1.1
1.7
1.8
1.4
1.2
1.9


YOR117W
0.8
1.3
1.7
0.8
1.2
1.1
3.3
1.0
3.5
1.8


YOR124C
0.6
1.1
1.3
0.8
1.1
0.9
1.1
1.3
2.0
1.9


YOR132W
0.9
1.6
0.8
2.8
1.1
1.6
1.4
1.2
2.8
1.6


YOR157C
1.0
1.3
1.2
1.3
0.7
1.2
1.2
1.2
5.7
2.6


YOR185C
1.1
1.3
1.9
1.1
1.2
3.0
1.3
1.4
1.9
2.9


YOR259C
0.8
1.1
0.8
0.9
2.0
0.8
1.3
1.1
2.7
1.5


YOR261C
1.0
1.4
0.6
0.9
1.5
1.4
1.9
2.6
5.5
2.5


YOR288C
0.9
1.3
1.1
1.1
1.1
1.0
2.0
1.9
0.9
1.0


YPL109C
1.1
2.5
0.5
1.2
1.2
1.2
1.8
1.1
1.2
1.5


YPL149W
1.5
1.5
0.6
2.8
0.8
0.9
1.2
1.1
5.6
3.7


YPL154C
0.7
3.3
4.2
1.2
1.2
3.5
1.5
0.8
2.8
1.7


YPR103W
0.7
1.1
1.3
0.7
1.7
1.2
1.6
1.0
5.5
2.0


YPR108W
0.8
1.0
1.3
0.6
1.3
1.5
1.6
1.6
3.7
2.8


YCL027W
0.7
2.0
1.0
1.0
1.2
1.3
1.0
0.6
0.7
16.3


YDR055W
1.7
2.1
2.2
2.8
1.7
3.9
1.5
1.6
0.8
2.4


YEL042W
0.6
0.9
1.7
0.9
0.7
0.5
0.5
0.7
0.2
0.3


YGR136W
0.9
1.2
1.3
0.7
1.2
1.1
1.5
1.3
2.1
2.2


YHR142W
1.5
0.8
2.1
0.8
1.3
1.2
0.9
1.3
0.4
0.9


YJL073W
0.8
0.8
2.5
0.7
1.2
2.0

1.0
1.7
0.7


YJR004C
0.2
0.8
3.4
0.6
1.1
1.2
0.4
0.4
0.3
0.7


YKL039W
0.8
1.1
2.4
0.8
0.7
4.9
2.0
0.8
1.3
3.3


YLR250W
1.5
1.0
1.0
1.4
1.4
1.1
1.9
1.3
2.7
2.4


YOR181W
1.0
0.9
1.1
1.4
0.7
0.9
0.7
0.7
0.6
0.5


YOR198C
1.0
0.7
1.4
1.0
0.8
0.9
1.6
1.3
2.4
1.4


YPL089C
1.2
1.0
0.5
1.8
1.4
0.8
0.9
0.8
0.4
2.5


YBR214W
0.9
2.1
5.7
2.0
1.1
0.8
1.1
0.7
2.2
3.5


YDR085C
1.9
1.8
1.6
3.4
0.9
2.1
4.1
2.0
0.4
2.3


YDR259C
1.4
1.0
0.4
1.4
1.0
0.5
2.8
1.4
1.0
1.8


YDR388W
0.7
0.7
1.2
1.0
0.7
1.0
1.1
0.8
1.4
0.9


YDR432W
0.5
0.8
1.0
1.4
1.6
0.6
0.5
0.5
0.7
0.8


YDR481C
0.7
2.3
1.3
0.7
1.0
0.9
0.7
1.0
1.9
1.6


YDR510W
1.0
1.3
1.5
1.3
0.7
1.0
1.6
1.5
2.7
2.5


YGR189C
1.1
0.9
1.5
3.5
0.7
0.5
0.6
1.0
0.3
0.9


YIL123W
1.0
0.5
1.2
1.5
0.6
0.5
0.5
0.6
0.1
0.2


YIL140W
0.7
1.0
1.5
1.4
0.8
0.5
0.5
0.7
0.7
0.6


YKL096W
1.4
0.6
8.1
1.6
0.6
0.6
0.2
0.5
0.0
0.5


YLR391W

0.7
2.9
0.8
1.2
1.5
0.7
0.7
0.4
0.7


YMR094W
1.0
0.5
1.3
1.7
0.9
0.5
0.8
1.0
−0.1
0.9


YMR104C
1.9
14.3
2.2
2.6
0.7
1.9
1.5
0.9
0.6
3.2


YMR276W
0.6
1.4
1.5
0.7
1.3
0.8
1.1
0.8
1.8
1.7


YOL013C
0.9
1.0
1.0
1.5
0.7
1.1
1.7
1.0
0.8
1.0


YOR355W
0.7
0.6
1.1
0.8
1.0
1.6
1.1
0.8
0.1
0.8


YCR071C
1.1
0.7
0.9
0.8
1.2
2.5
1.4
0.9
0.6
1.2


YDL008W
1.1
1.0
1.0
1.1
1.8
2.7
2.0
1.2
2.3
3.0


YDR115W
1.3
0.9
0.6
1.5
1.4
2.3
1.6
1.3
1.1
1.0


YER130C
0.9
1.6
0.5
0.8
1.7
2.7
1.5
1.2
0.5
1.3


YMR226C
1.1
1.8
1.4
1.6
0.9
2.6
1.8
1.6
2.6
2.2


YOR383C
0.9
4.3
2.6
0.9
0.9
6.8
8.0
1.0
1.2
4.5


YAR010C
0.8
1.2
1.2
0.8
1.0
2.3
1.9
1.3
1.2
1.1


YBL043W
1.2
1.2
1.1
1.3
1.1
26.9
1.5
2.1
0.5
14.7


YCR004C
1.7
1.0
12.0

1.2
1.8
1.4
1.2
4.7
2.1


YCR088W
0.9
1.1
1.2
0.9
1.1
2.0
1.2
0.5
0.8
0.9


YDL238C
0.7
1.0
1.1
1.7
0.9
2.1
1.4
5.8
1.7
2.7


YDR084C
0.9
0.9
1.5
1.1
1.2
2.1
0.9
0.7
0.6
0.6


YDR104C
0.8
1.1
1.2
1.2
1.3
1.7
1.0
1.3
2.8
2.7


YDR315C
1.0
1.4
1.0
1.3
0.9
9.4
1.4
1.4
1.1
1.6


YDR358W
0.7
1.1
0.7
1.1
1.4
2.5
2.8
1.2
2.9
3.2


YEL066W
2.0
2.9
1.5
2.2
0.8
2.2
1.8
1.4
1.3
2.4


YER039C
1.0
1.2
1.0
4.1
1.5
1.6
1.3
0.7
1.2
0.8


YER107C
0.9
0.5
1.0
0.6
1.3
2.5
1.0
0.8
0.4
0.5


YFL028C
1.2
1.1
0.7
1.5
1.7
1.7
2.0
1.5
2.7
1.8


YFL043C
1.0
1.2
0.6
1.2
1.2
1.8
1.8
1.0
2.2
3.8


YGL229C
0.6
0.7
0.9
0.8
1.0
2.2
2.2
0.7
1.8
1.7


YGR257C
0.7
0.8
0.9
1.1
1.3
2.1
2.4
1.0
1.5
1.9


YHR004C
0.9
1.1
0.8
1.1
1.5
2.0
1.5
0.9
1.1
0.6


YHR071W
1.5
1.1
0.6
1.6
1.5
2.0
1.0
1.7
1.0
7.2


YJL089W
1.1
1.5
1.0
0.8
1.1
1.6
1.1
1.1
1.6
3.9


YJL116C
0.9
1.8
1.3
1.9
1.3
3.4
0.8
1.8
2.4
2.6


YJR086W
1.2
1.1
0.8
1.4
1.3
1.9
1.7
1.1
1.4
1.1


YKL008C
1.2
0.6
2.0
0.8
0.9
3.8
1.4
1.2
0.3
0.4


YKL013C
1.4
0.9
1.4
1.1
1.9
1.9
1.8
0.9
1.5
1.4


YKL041W
1.2
0.8
1.1
1.0
1.3
2.2
1.0
1.6
1.6
1.5


YKL139W
0.9
0.7
1.4
0.8
2.8
3.5
2.6
1.2
1.6
1.5


YKR014C
1.1
1.3
0.7
1.1
1.5
2.1
1.7
1.6
2.4
2.0


YLR093C
1.3
0.8
0.7
1.2
1.4
2.9
1.9
1.2
1.5
1.3


YLR118C
1.0
1.1
1.6
1.0
1.0
2.5
1.5
1.0
1.1
1.3


YLR251W
1.8
0.8
4.2
4.6
1.6
2.1
2.6
1.2
2.1
1.3


YMR027W
0.8
2.6
0.7
0.8
1.1
2.1
2.0
0.9
1.1
1.4


YMR262W
1.0
1.3
1.9
1.1
1.2
2.0
1.9
1.0
3.0
1.2


YNL214W
1.2
0.9
1.1
1.1
1.4
2.3
1.3
1.1
1.5
1.5


YOR149C
0.7
0.9
1.0
0.8
1.1
2.3
1.0
0.7
0.4
1.0


YOR165W
0.9
1.5
0.7
0.8
0.8
2.2
0.9
1.1
0.8
1.3


YOR285W
1.4
6.0
3.5
1.9
1.7
2.1
4.0
1.2
4.0
2.9


YOR367W
1.0
0.9
1.7
0.9
1.1
3.3
1.9
1.1
1.1
1.1


YPL018W
1.0
1.4
1.0
0.5
1.8
2.1
0.9
1.1
1.4
1.2


YPL203W
1.3
1.0
2.2
1.0
2.1
1.8
2.1
1.1
1.8
2.1


YPL255W
0.8
0.3
1.1
0.6
0.9
2.0
0.6
0.9
0.1
0.1


YPR073C
1.2
1.9
0.5
1.4
1.8
2.0
2.5
1.5
1.3
2.6


YDR518W
0.8
1.7
1.1
1.2
1.6
1.2
2.7
1.1
0.2
1.2


YOR381W
0.8
2.0
0.8
1.8
1.0
1.0
3.6
0.8
1.2
3.5


YBR109C
1.6
1.3
2.4
1.1
1.0
1.4
2.4
1.7
3.8
3.3


YBR201W
1.2
4.3
1.2
2.4
1.2
1.0
3.4
2.2
0.8
1.0


YDR041W
1.2
1.1
0.6
1.8
2.0
1.6
2.4
1.2
1.3
1.3


YER136W
0.9
1.1
1.1
1.4
1.6
1.3
2.1
1.3
1.4
1.6


YER159C
1.1
0.9
0.2
1.6
2.1
1.3
2.0
1.4
0.2
0.9


YJL030W
1.6
1.4
0.5
1.0
1.3
1.1
1.9
1.6
2.3
1.9


YJR029W
0.8
1.3
0.6
0.8

1.0
2.4
0.9
1.1
1.5


YJR099W
1.4
0.9
1.1
1.3
1.5
2.1
2.0
1.4
1.4
2.4


YJR122W
2.0
1.4
2.5
1.1
1.3
1.4
1.8
1.4
5.3
6.1


YJR125C
1.0
1.0
1.2
1.0
1.2
1.3
1.9
0.9
1.8
1.3


YKL190W
1.1
1.3
0.4
0.9

1.5
2.0
1.1
1.8
1.9


YLL051C
0.8
1.1
1.0
1.5
1.4
1.2
2.0
0.9
0.9
1.8


YLR090W
0.7
1.1
0.8
1.3
1.2
1.3
2.2
0.9
1.8
1.4


YMR051C
0.9
2.8
0.8
1.3
1.7
1.2
2.6
0.9
1.0
1.4


YMR139W
1.0
3.4
2.5
1.5
1.2
1.5
2.2
0.9
2.8
2.4


YNL015W
2.3
6.7
1.8
2.4
1.8
1.7
3.5
2.2
2.1
4.3


YNL079C
1.1
1.0
0.4
1.0
1.7
1.1
1.9
1.6
1.5
1.2


YNL223W
1.1
1.2
0.6
1.7
1.0
1.8
2.2
1.4
3.3
1.9


YNR007C
1.2
1.8
0.7
1.0
1.5
1.3
1.9
1.2
2.5
2.0


YNR035C
0.8
1.2
1.7
1.0
0.8
1.1
2.6
1.1
2.9
1.5


YOL016C
1.3
2.0
0.4
2.0
1.6
0.9
3.0
1.3
1.9
1.6


YOL104C
1.0
1.7
0.2
1.8
1.9
1.4
2.6
1.4
0.2
1.7


YPR107C
1.4
1.0
1.2
1.9
1.5
1.3
2.0
1.3
2.4
2.4


YOL152W
0.2
0.6
1.0
0.8
0.7
1.8
2.4
4.1
0.9
1.2


YAL007C
1.3
0.9
0.9
1.5
0.6
0.7
1.5
1.7
1.1
0.9


YDL043C
1.0
0.8
0.8
1.2
1.1
0.5
0.9
1.3
0.8
0.8


YDL212W
1.0
1.2
1.6
1.2
1.1
0.4
0.7
0.9
0.4
0.6


YDR183W
1.2
0.7
0.9
1.4
1.5
1.4
1.8
1.8
2.5
2.9


YGL089C
0.4
0.7
2.0
1.0
1.5
0.5
0.4
1.0
0.0
1.9


YGL096W
1.9
2.9
1.2
2.5
0.9
0.5
1.8
1.7
2.1
3.6


YGR006W
1.2
1.1
0.9
2.9
0.5
0.5
1.0
1.2
0.7
0.9


YHL034C
0.7
1.0
0.7
0.8
1.9
1.1
1.4
1.4
1.9
1.9


YHR163W
0.9
1.2
1.3
1.2
0.8
1.9
0.9
1.3
1.4
1.1


YIR024C
1.5
0.9
0.9
2.0
1.1
0.8
1.5
1.4
5.6
2.9


YKL070W
1.0
0.8
1.7
0.9
1.3
1.1
1.1
1.5
15.0
11.0


YLL050C
1.4
1.0
1.2
1.7

1.9
1.4
1.3
1.0
1.0


YLR220W
0.9
0.6
3.0
1.0
0.9
0.3
0.4
1.0
0.4
0.4


YLR390W
0.9
0.9
1.2
1.7
1.2
0.7
1.5
0.8
1.7
1.7


YOL044W
1.0
1.4
1.0
1.3
1.0
1.2
1.2
1.1
1.6
1.4


YOL147C
1.6
1.1
2.4
1.5
0.7
0.9
0.6
1.5
0.5
0.7


YDR069C
1.4
0.8
3.0
1.5
1.6
0.7
1.0
1.8
1.8
4.5


YER131W
1.5
0.3
0.9
0.7
1.6
0.9
0.6
2.0
0.0
0.6


YGR044C
0.8
1.3
0.7
1.2
1.1
1.4
1.3
1.8
0.9
0.8


YMR240C
1.1
0.6
2.5
0.7
1.4
0.8
1.1
2.3
0.5
1.1


YBR105C
1.7
1.5
0.9
2.0
0.8
1.8
2.0
1.2
1.1
3.3


YBR182C
2.0
1.9
1.0
2.4
1.4
1.0
1.7
1.3
0.6
3.2


YBR186W
1.0
1.0
1.1
1.7
1.0
0.5
0.9
0.9
1.0
2.4


YEL052W
1.1
1.0
2.0
2.0
1.3
1.2
1.2
1.2
3.0
3.4


YER098W
0.9
0.9
0.5
1.1
1.4
1.6
1.3
1.7
2.8
3.3


YGL240W
0.9
1.2
0.8
1.8
1.2
1.1
1.2
0.8
2.0
3.4


YGR067C
2.2
1.4
1.2
4.6
1.6
1.3
1.5
1.5
0.7
6.7


YGR133W
1.0
1.1
0.7
0.6
1.3
1.2
1.2
1.2
1.3
3.6


YHR124W
1.1
1.1
1.5
2.0
0.9
0.8
1.2
1.1
3.0
6.8


YJL103C
1.3
1.8
3.8
1.3
1.1
1.0
0.7
0.8
2.3
2.4


YJR036C
1.2
1.2
1.0
4.3
1.5
0.9
1.0
1.0
1.4
3.0


YLR216C
1.2
2.3
3.3
1.1
1.2
1.2
5.2
1.3
14.1
4.1


YLR389C
0.8
6.4
2.3
0.6
0.7
0.2
1.0
1.0
2.4
2.8


YNL128W
1.3
4.6
1.1
0.8
1.2
1.1
1.0
1.3
2.9
2.4


YOL133W
1.0
1.6
1.4
1.2
0.9
1.6
1.8
1.0
4.7
3.8


YOR133W
1.1
1.3
1.6
1.3
1.3
0.9
1.1
0.8
3.1
4.9


YOR227W
1.1
2.4
3.2
0.9
0.5
1.0
1.0
0.7
2.9
3.0


YPR015C
1.3
1.3
1.5
1.7
1.1
0.7
1.3
1.2
5.6
5.3


YPR086W
1.0
1.4
0.7
0.7
1.2
1.1
1.6
1.3
3.0
2.9


YBL056W
0.7
0.7
1.1
1.2
1.8
1.6
1.4
1.3
3.6
2.2


YBR026C
1.1
1.7
2.8
0.9
1.2
0.1

1.1
3.4
1.6


YBR123C
0.8
0.7
1.6
1.8
1.1
1.3
0.9
0.9
3.2
2.5


YDR099W
0.9
1.0
2.0
1.3
1.1
2.2
1.3
1.1
2.4
1.3


YDR177W
1.2
1.7
1.0
1.0
1.0
1.4
1.3
1.6
3.5
1.9


YDR392W
0.9
2.9
1.1
1.3
1.2
0.6
1.1
1.1
4.3
1.5


YDR394W
0.9
1.2
1.3
0.8
1.2
1.1
1.2
1.3
3.8
2.0


YER184C
2.3
1.6
1.1
2.3
1.0
0.6
0.9
1.1
4.6
3.2


YFL059W
1.2
1.4
1.2
2.2
1.1
1.0
1.3
1.5
4.1
4.2


YGL185C
1.3
1.9
1.9
1.9
0.8
0.8
1.9
1.5
4.1
2.3


YHL019C
1.1
0.8
1.2
0.6
1.0
1.2
1.1
1.0
2.1
1.4


YHR012W
1.1
1.0
1.2
1.0

1.6
1.2
1.2
4.9
2.2


YHR028C
0.8
1.2
1.4
0.8
1.0
0.9
1.2
0.8
3.7
2.2


YHR109W
0.8
1.0
0.0
0.7
1.3
1.4
1.4
1.2
2.4
1.8


YHR156C
1.3
1.3
0.9
2.1
1.9
1.0
1.2
1.2
3.6
1.9


YIL159W
1.1
1.6
1.3
0.7
1.2
2.3
0.6
1.1
5.9
1.6


YJL154C
0.6
2.7
0.7
0.6
1.2
1.3
1.5
1.0
2.3
2.0


YJR110W
1.0
0.6
1.0
1.4
1.3
0.9
0.9
1.1
4.9
2.3


YKL025C
0.7
1.1
1.1
0.9
1.1
0.9
0.9
0.9
2.8
1.7


YKL171W
0.9
1.3
1.2
2.1
0.9
0.4
0.9
0.8
8.2
1.8


YKL196C
1.2
1.1
0.5
0.9
1.3
0.9
1.5
1.3
4.3
2.0


YKR068C
1.2
1.5
1.0
1.8
1.1
1.4
1.4
1.3
2.4
1.9


YLR144C
0.8
1.5
4.0
1.3
0.7
0.9
0.7
1.1
2.8
1.5


YML112W
1.0
1.0
1.1
2.0
1.0
1.4
0.9
1.3
3.2
2.4


YOL038W
0.9
1.0
0.4
1.6
1.8
1.2
1.4
1.4
3.5
2.7


YOR257W
1.1
2.5
0.8
1.1
1.1
0.8
1.3
1.5
3.4
1.4


YOR265W
1.4
1.0
0.8
1.0
1.2
1.4
1.3
1.4
3.5
2.2


YPL124W
1.3
1.3
0.7
0.7
1.6
0.8
0.9
1.8
2.2
1.0


YPR125W
0.6
1.3
0.9

1.2
0.7
1.3
1.2
4.1
1.8


YPR168W
0.9
1.0
0.2
0.5
1.3
0.4
1.1
1.1
4.7
2.7


YPR180W
0.9
1.2
1.6
1.0
1.0
0.8
2.4
1.3
2.3
1.1


YPR193C
1.0
2.2
0.6
1.1
1.4
1.3
1.4
1.1
3.5
4.1


YBR045C
0.9
1.0
2.2
0.7
1.0
0.8
0.8
1.0
3.6
1.1


YBR128C
1.0
1.1
2.1
1.0
1.1
1.5
2.1
1.2
2.8
1.2


YCL055W
0.7
2.2
0.7
1.3
1.2
1.4
1.0
1.3
2.1
1.5


YCR019W
1.0
1.6
1.0
0.8
1.4
1.5
1.1
1.5
2.8
1.6


YDL065C
1.2
0.9
1.0
0.7
1.4
1.1
1.3
1.4
2.4
1.5


YDL143W
0.8
0.8
1.2
1.1
1.0
1.0
0.9
1.2
2.1
1.8


YDL197C
1.0
1.1
0.9
2.1
1.5
1.2
1.0
1.0
2.6
1.5


YDL230W
1.0
0.8
1.2
1.3
1.4
0.9
1.1
0.9
2.6
1.2


YDR212W
0.8
1.2
1.3
0.8
1.4
1.4
1.0
1.3
3.5
1.7


YDR257C
0.8
5.3
0.6
0.8
1.6
1.1
1.0
1.0
3.0
1.6


YDR329C
0.9
0.8
1.0
1.7
1.9
1.2
1.6
1.2
2.5
1.0


YDR488C
1.0
0.3
0.9
0.9
0.9
0.9
0.7
0.9
2.1
0.4


YDR505C
0.8
1.0
1.0
1.4
1.2
1.1
1.2
0.8
2.5
1.0


YDR506C
0.9
0.7
1.3
0.7
0.9
0.9
0.6
1.0
1.9
1.4


YDR515W
0.9
1.1
0.8
0.8
1.5
0.8
0.6
1.4
5.8
2.7


YEL005C
1.1
1.3
0.8
1.1
1.6
1.9
2.0
1.2
2.3
1.6


YER048C
0.8
1.2
0.4
1.4
1.8
1.9
1.9
1.6
2.3
1.1


YER078C
0.9
0.8
1.8
0.8
0.9
1.4
1.3
1.1
2.3
1.5


YER089C
0.5
0.5
1.4
1.1
0.8
0.6
0.9
0.5
2.0
2.3


YER100W
1.1
1.1
0.7
0.7
0.9
0.5
0.6
1.2
2.3
1.6


YFR051C
0.5
1.1
2.2
0.5
0.5
0.2
1.0
0.8
2.5
1.4


YGL093W
0.8
0.9
1.2
0.6
0.9
1.0
0.8
0.8
4.5
1.6


YGL105W
0.9
0.8
1.1
0.8
1.3
1.5
0.7
1.2
1.8
1.4


YGL166W
1.0
1.4
0.6
1.5
1.3
1.0
1.5
1.2
1.8
2.4


YGL215W
0.7
1.2
1.2
0.9
1.0
0.9
1.0
0.7
2.2
1.8


YGL216W
0.7
1.3
0.8
1.0
1.2
1.5
1.0
1.0
2.6
0.5


YGL221C
1.1
1.2
1.0
1.1
0.9
2.2
1.3
1.6
3.4
1.9


YGR186W
0.9
0.7
0.4
1.1
1.5
0.7
1.3
1.3
2.6
1.9


YGR270W
0.9
1.0
0.8
0.8
0.7
0.9
0.9
0.9
2.3
1.3


YGR274C
0.7
0.5
0.3
0.9
1.8
0.7
1.3
1.2
2.2
1.8


YHR082C
0.7
1.1
1.6
0.9
1.6
0.8
1.1
0.8
2.6
1.7


YHR160C
1.0
0.5
1.6
1.6
1.0
1.0
1.1
1.2
2.3
1.6


YHR171W
1.2
0.8
1.1
1.2
1.3
2.0
1.9
0.9
2.1
1.6


YHR205W
0.7
1.3
0.6
0.8
1.3
1.0
0.7
0.5
2.0
0.6


YIL062C
1.1
1.0
1.3
1.2
1.2
0.9
0.4
1.1
2.8
2.3


YIL075C
0.5
0.7
1.5
0.6
1.1
0.8
0.8
0.7
1.9
2.3


YIR009W
0.8
0.8
0.9
2.8
1.5
1.4
1.3
1.3
2.6
1.5


YIR018W
1.2
1.0
0.9
1.1
1.4
2.0
1.5
1.5
4.0
2.1


YJR091C
0.8
1.2
2.6
1.4
1.4
0.8
1.1
0.8
2.4
2.3


YKL079W
0.9
0.8
1.5
1.0
1.4
0.8
1.7
1.2
2.3
2.0


YKR102W
0.8
1.6
1.4
0.8
0.9


0.7
2.4
1.4


YLL054C
1.2
0.6
0.5
1.2
1.4
1.9
1.1
1.1
2.4
1.4


YLR200W
1.4
0.9
0.5
1.2
1.7
1.2
1.9
1.4
2.2
2.6


YLR248W
0.9
0.7
1.1
1.4
1.9
1.2
1.2
1.1
2.3
1.1


YLR266C
0.9
1.3
0.7
1.5
0.7
1.0
1.6
1.1
2.2
2.6


YML088W
0.9
1.6
0.3
0.5
1.5
0.7
1.1
1.1
4.0
2.2


YMR091C
1.0
0.7
0.8
1.0
0.7
0.8
0.8
1.3
2.1
1.3


YMR110C
1.0
1.4
1.8
1.9
1.3
2.1
1.9
0.9
2.3
1.6


YMR255W
1.2
1.4
0.7
1.8
1.3
0.9
1.5
1.4
2.8
2.4


YNL039W
0.7
0.8
0.3
0.4
2.1
0.8
1.1
1.2
2.1
1.8


YNL077W
1.5
1.1
2.3
1.2
1.5
0.9
1.2
1.0
4.4
5.1


YNL083W
0.8
1.4
1.3
1.2
0.8
0.7
0.9
1.1
3.1
1.6


YNL147W
1.3
2.4
0.6
0.7
2.0
1.5
1.4
1.8
2.1
2.9


YNR006W
1.1
1.8
0.5
0.9
1.5
0.9
1.5
0.9
2.2
2.3


YNR034W
0.9
1.4
5.3
1.6
1.0
0.9
1.3
1.0
3.0
2.1


YNR047W
0.7
1.0
1.7
0.5
1.1
1.0
1.0
0.8
2.0
1.2


YOR023C
0.7
1.2
1.3
0.8
1.2
1.8
1.1
0.6
3.5
1.3


YOR058C
2.0
1.4
2.0
0.6
0.9
0.9
0.8
1.7
6.4
4.5


YOR069W
0.8
1.6
0.7
1.3
1.0
0.5
1.2
1.1
1.9
1.4


YOR229W
0.9
0.9
1.0
0.8
1.5
1.3
1.1
0.8
2.5
0.8


YOR256C
1.0
0.8
0.9
1.5
1.7
0.9
1.4
1.1
2.7
1.8


YPL020C
1.1
0.7
0.7
1.3
0.8
0.8
1.1
1.1
2.3
1.6


YPL105C
0.6
0.8
0.6
0.7
1.1
1.2
0.7
1.0
3.4
1.4


YPR066W
1.2
2.2
1.1
2.2
1.3
0.7
1.3
0.8
2.3
1.9


YPR081C
0.9
1.0
1.0
1.1
0.8
1.1
1.1
1.0
4.2
2.6


YPR140W
0.9
1.2
0.8
1.8
0.9
3.0
1.9
1.1
2.1
1.3


YPR155C
0.9
2.5
1.5
1.4
0.9
0.9
1.4
1.0
2.0
1.3


YPR185W
0.7
0.9
0.3
0.4
1.1
0.9
1.2
1.0
2.5
1.7


YBR076W
2.3
1.1
1.4
5.0
0.9
0.8
1.0
0.7
0.4
1.8


YDR373W
1.7
0.8
0.5
1.3
1.8
0.9
1.4
1.9
2.5
2.8


YFR014C
2.1
2.4
0.8
2.6
0.7
0.8
1.4
1.3
1.0
1.6


YHR136C
2.4
13.6
1.4
2.1
2.4
1.4
0.5
1.3
0.1
2.0


YIL129C
0.8
5.8
1.0
1.2

0.3


2.1
1.8


YMR077C
1.1
3.9
1.1
1.8
1.0
0.5
1.4
1.7
1.9
2.5


YBR264C
1.2
3.7
1.5
1.5
0.7
0.9
1.3
1.2
0.9
1.1


YPL177C
1.2
3.7
0.9
1.3
0.7
0.8
0.8
1.3
0.5
1.0


YGL056C
0.7
3.5
1.3
1.0
0.6
0.4
1.0
0.9
0.4
0.6


YBL101W-A
1.0
5.7
0.7
0.6
1.0
1.4
1.3
1.5
1.2
2.1


YER072W
1.6
2.3
1.6
1.3
1.2
1.5
0.7
1.2
0.5
1.1


YMR112C
1.2
4.2
0.9
1.2
1.0
0.7
1.5
1.6
1.4
1.3


YJR058C
1.3
2.0
1.3
1.5
1.1
1.6
1.3
1.2
1.9
2.6


YML055W
1.7
2.3
0.6
2.0
0.9
1.2
1.7
1.7
1.0
1.4


YDR080W
0.9
1.8
0.5
0.6
1.2
1.5
1.6
1.2
1.7
2.6


YNR030W
0.6
2.1
2.2
0.7
0.8
1.2
1.0
0.6
1.0
1.4


YNL196C
1.1
1.8
1.4
1.3
0.9
1.2
1.0
0.7
0.5
2.2


YOR148C
1.4
1.4
0.5
1.8
0.9
0.9
1.2
1.5
0.8
0.8


YER029C
1.0
1.6
0.4
1.9
1.7
1.2
1.1
1.5
1.4
1.1


YLR360W
0.9
2.0
0.5
0.7
1.9
1.4
1.7
1.3
0.9
1.3


YGR239C
1.3
1.3
0.7
1.3
1.2
2.3
1.2
1.5
0.5
3.8


YDL229W
0.9
1.9
0.4
0.6
1.2
1.0
1.3
1.2
1.4
0.9


YJR027W
0.8
1.9
0.8
0.7

1.5
2.0
1.0
1.2
1.3


YKL198C
1.2
1.4
0.8
0.2
0.9
1.0
1.2
0.6
0.0
0.8


YBR031W
1.1
0.8
4.1
1.4
1.4
0.7
0.5
1.0
0.1
1.0


YBR118W
1.3
0.8
2.9
1.2
1.0
1.3
1.0
1.3
0.5
0.9


YCR106W
0.9
1.1
2.8
1.1
0.8
1.4
0.9
0.8
2.0
1.2


YDR012W
0.9
0.8
3.9
1.2
1.1
0.9
0.5
1.1
0.3
0.7


YDR134C
1.0
0.7
3.9
1.9
0.8
1.1
0.4
0.6
0.1
0.5


YDR276C
1.5
1.6
6.1
1.4
0.7
1.1
1.0
1.1
1.1
2.7


YGR279C
0.9
0.7
3.6
1.0
1.2
1.6
0.8
0.6
0.3
0.7


YJL059W
1.0
1.7
3.1
0.8
0.9
1.6
1.1
0.8
1.7
1.6


YKL056C
1.3
0.7
2.6
1.4
1.7
0.9
0.5
1.0
0.1
0.7


YKL097W-A
1.5
1.3
4.2
1.3
1.2
0.9
0.2
0.7
0.0
0.4


YNL209W
0.9
0.9
2.7
0.9
1.3
0.9
0.5
1.1
0.2
0.8


YNL307C
0.8
0.6
3.1
1.3
1.0
1.9
0.9
0.9
1.0
0.9


YPR028W
1.0
1.1
4.0
1.7
1.0
1.4
0.8
0.7
0.5
0.8


YPR149W
1.0
1.1
5.9
1.7
1.7
1.6
2.1
0.6
1.2
1.8


YAL016W
0.8
1.0
2.8
0.9
0.9
0.9
1.1
1.0
1.2
1.9


YBR283C
0.6
0.7
1.9
1.2
1.4
2.2
0.8
0.8
1.5
1.2


YBR286W
0.7
1.4
3.8
1.2
1.3
1.5
1.3
0.9
1.2
1.6


YCL008C
0.8
1.1
1.8
1.2
1.2
0.9
0.9
0.7
0.9
1.4


YCR069W
1.0
1.2
2.0
0.9
1.1
1.4
1.1
0.7
0.8
0.7


YDL061C
1.4
0.5
2.9
0.9
1.3
1.1
0.5
1.0
0.0
0.5


YDR151C
1.3
1.0
2.3
1.8
0.8
0.7
0.8
1.5
2.6
2.8


YDR382W
1.3
0.5
2.4
1.2
1.1
0.6
0.4
1.2
0.0
0.4


YDR385W
0.6
0.4
3.5
0.9
1.1
0.5
0.4
0.7
0.2
0.5


YDR407C
0.7
1.0
2.0
0.7
0.8
1.2
1.4
0.9
1.5
1.7


YGL206C
0.4
3.5
2.0
0.5
0.6
0.8
0.8
0.5
0.7
0.7


YGR172C
0.6
1.3
2.5
1.3
0.6
0.9
1.0
0.8
0.4
1.1


YIL015W
1.1
1.7
2.0
2.5
0.9
0.4
0.9
0.9
0.3
1.1


YIL018W
1.0
0.4
2.3
1.4

0.9
0.4
0.8
0.0
0.3


YJL138C
1.0
0.7
2.3
1.4
0.9
0.8
0.8
1.2
0.2
0.7


YJL191W
1.0
0.4
2.2
0.7

1.3
1.0
0.8
0.0
0.4


YJR047C
1.1
0.8
2.6
1.1
1.1
1.1
0.4
0.9
0.7
0.5


YJR119C
0.9
1.0
2.0
1.0
0.9
1.4
1.1
1.6
0.5
1.3


YJR123W
1.2
0.6
2.2
1.0
1.3
1.0
0.4
1.2
0.0
0.5


YJR145C
0.8
0.7
2.3
1.3

0.4
0.4
1.0
0.0
0.4


YLR110C
1.4
0.8
2.7
1.2
1.7
0.9
0.4
0.8
0.3
0.8


YLR264W
1.1
0.4
2.2
1.0
1.1
0.7
0.4
1.0
0.0
0.3


YLR340W
0.8
0.4
2.6
1.0
0.6
0.7
0.3
0.9
0.0
0.5


YLR388W
1.6
0.4
1.9
1.0
2.5
0.7
0.5
1.2
0.2
0.7


YMR092C
0.6
1.2
1.9
1.3
0.8
0.9
1.2
0.9
1.5
1.7


YMR101C
1.1
1.8
1.9
2.9
0.9
0.4
0.9
0.8
−4.0
1.6


YNL069C
1.2
0.3
2.8
2.3
0.7
0.4
0.3
1.0
0.0
0.4


YNL135C
1.1
0.9
2.0
1.4
1.7
0.9
0.8
0.5
0.7
0.5


YOL039W
1.2
0.3
3.9
0.7
1.3
0.4
0.3
1.0
0.0
0.9


YOL120C
1.0
0.3
2.3
0.8
1.5
0.3
0.4
0.8
0.0
0.3


YOR230W
1.2
2.3
3.0
1.0
0.9
1.1
0.6
0.6
0.6
0.7


YOR298W
0.9
0.9
3.2
0.5
1.5
0.9
0.6
0.7
0.6
1.0


YPL048W
0.7
0.7
2.6
1.2
0.7
0.6
0.6
0.8
1.6
0.6


YPL179W
1.0
1.5
2.4
1.0
1.1
1.6
1.2
0.8
1.2
1.1


YPL218W
1.5
0.9
2.5
1.7
1.1
1.5
1.3
1.4
1.1
1.2


YPL220W
1.3
0.9
2.3
1.4
1.1
1.3
0.6
1.2
0.0
0.5


YPR080W
1.3
1.3
2.8
1.2
1.4
1.4
0.9
1.3
0.7
1.1


YPR181C
0.5
0.8
2.3
0.6
1.0
2.0
1.3
0.5
1.0
0.7


YBR290W
1.3
1.4
0.8
3.0
1.0
1.1
1.4
1.5
2.0
1.8


YCR091W
1.3
1.1
0.6
2.2
1.3
1.3
1.3
1.1
0.8
1.2


YFL026W
1.0
0.8
1.2
5.0
1.4
1.0
1.2
1.3
0.6
1.5


YOR003W
0.9
1.1
1.3
3.3
1.6
1.1
1.1
0.9
1.6
1.3


YCR038C
0.9
1.1
0.9
2.5
0.9
0.9
0.9
0.9
0.7
0.7


YDL119C
1.0
0.8
0.6
2.2
0.9
0.6
1.3
1.1
1.3
1.1


YDL220C
0.9
1.3
1.1
1.6
1.2
1.8
1.1
0.8
0.2
1.3


YDR125C
1.1
0.9
1.0
1.7
1.1
0.8
1.0
1.2
0.7
1.9


YDR225W
1.0
0.6
0.6
1.6
1.9
0.5
0.4
0.8
0.3
0.7


YER066W
0.9
0.7
0.9
2.1
1.5
1.3
1.3
0.7
1.7
1.4


YER076C
0.8
0.9
1.2
1.9
1.1
0.6
0.8
0.7
0.2
1.2


YFR006W
0.9
1.8
1.1
3.4
0.7
0.8
1.4
1.0
−1.6
0.7


YGL208W
0.9
1.8
1.1
2.2
0.7
0.6
1.1
0.7
1.4
1.3


YGR023W
1.0
0.9
1.1
4.2
1.0
1.2
1.0
1.2
1.2
3.2


YGR108W
0.9
3.9
0.3
3.6
0.8
0.1
0.3
0.5
0.0
0.1


YHR195W
1.1
1.5
0.6
2.4
1.5
1.0
1.3
1.6
1.8
0.8


YIL050W
1.0
1.3
1.3
2.4
0.9
0.7
1.1
1.2
1.3
1.9


YJR050W
1.0
0.6
0.7
2.1
1.2
1.4
1.1
1.8
2.0
1.3


YKL093W
1.0
1.6
1.4
3.6
0.8
0.8
0.7
0.9
1.5
1.6


YMR053C
1.1
1.0
0.8
2.1
0.9
1.3
0.9
1.0
2.2
1.4


YNL139C
0.8
1.1
0.8
2.0
1.9
1.0
1.0
0.9
0.6
0.7


YOR122C
1.0
0.7
1.8
1.9
1.7
1.3
1.2
1.0
1.1
0.9


YOR312C
1.2
0.4
1.0
1.9
0.7
0.6
0.6
1.2
0.0
0.3


YOR327C
2.3
1.8
0.5
1.9
1.0
1.4
1.4
1.9
1.4
2.2


YPL001W
0.9
0.9
1.0
2.5
1.7
0.7
1.0
1.2
0.7
1.0


YPL230W
1.2
1.7
1.8
4.0
0.8
1.0
1.1
1.0
0.9
2.7


YER025W
0.6
0.7
0.6
0.6
1.5
1.0
1.5
1.1
0.4
0.6


YHR185C
0.9
1.1
1.4
0.7
1.4
1.0
1.3
0.8
−0.6
0.9


YIL076W
1.3
0.6
1.1
1.0
1.8
0.6
0.5
1.3
1.0
1.4


YMR238W
1.9
1.3
1.1
1.3
1.5
1.3
1.2
0.9
1.3
1.4


YBR009C
1.6
0.8
0.4
1.7
1.4
1.0
0.5
1.2
0.6
0.6


YBR010W
1.0
0.8
0.5
2.0
0.8
1.1
0.8
1.3
0.5
0.7


YCL067C
1.2
1.1
0.3
1.7
1.1
1.7
1.3
1.7
1.4
1.9


YCR096C
1.1
0.9
0.4
1.6
2.1
1.2
1.7
1.5
1.2
1.6


YDL137W
1.4
1.1
1.2
1.2
1.8
1.0
2.0
1.1
1.1
1.3


YDL192W
1.4
1.0
0.6
1.2
1.4
1.0
1.7
1.5
0.8
0.6


YDR224C
1.1
0.7
0.8
0.9
1.2
1.0
0.8
1.4
1.1
1.3


YDR378C
1.3
1.3
1.4
1.3
1.0
1.0
1.4
1.5
0.5
1.3


YMR197C
1.3
1.6
1.4
1.9
1.1
1.6
1.5
1.4
1.9
2.5


YOL109W
2.0
2.0
1.5
1.8
1.0
1.3
1.2
1.5
0.1
1.1


YPL010W
1.0
1.1
0.9
1.0
1.4
1.0
1.9
1.5
1.7
1.5


YHR132C
0.8
0.7
1.7
1.4
1.0
0.7
0.8
0.8
0.9
1.1


YJL141C
1.0
0.8
1.0
1.6
1.5
1.1
1.1
0.9
1.2
1.3


YKR098C
1.0
1.1
1.2
1.7
1.1
1.8
1.7
1.3
1.4
2.7


YLR206W
0.7
1.6
1.4
1.1
1.1
0.5
0.7
0.8
1.5
1.0


YAL055W
1.2
1.0
0.9
1.0
1.4
1.3
1.5
1.9
1.0
1.4


YAR062W
1.2
1.8
1.4
0.7
1.0
0.6
1.3
0.9
0.4
0.9


YBL102W
0.8
1.0
1.4
1.2
0.9
2.5
1.6
0.8
2.3
1.1


YBR161W
1.2
0.8
2.3
0.7
1.1

3.0
0.9
0.4
0.4


YCR039C
1.9
2.1
0.3
0.9
1.9
1.5
1.4
1.6
1.8
2.2


YDL018C
1.3
0.9
0.9
1.1
1.8
1.4
1.2
1.3
1.0
1.0


YDR022C
1.1
1.2
0.8
0.9
1.5
2.2
1.8
1.4
0.9
1.4


YDR181C
1.1
1.2
0.8
1.4
0.9
0.7
1.0
1.2
2.0
0.9


YGR036C
0.9
0.8
0.9
1.1
1.3
1.3
1.0
0.8
0.9
0.9


YGR120C
1.2
1.8
0.5
1.0
1.8
1.5
1.6
1.3
0.3
1.2


YGR131W
0.8
2.1
1.9
1.1
0.9
1.9
1.1
1.1
1.9
5.8


YGR167W
1.1
1.1
0.6
1.5
0.9
1.7
1.4
1.4
1.4
1.9


YHL024W
1.2
0.8
1.6
1.1
1.5
1.2
1.3
0.8
2.1
3.6


YJL113W
1.2
1.9
1.2
1.2

0.7
1.2
1.3
1.3
2.1


YJL146W
1.3
1.9
1.2
2.0
0.8
0.7
1.3
1.0
1.0
1.7


YJR019C
0.8
1.8
1.9
1.6
1.1
0.8
0.9
0.7
1.1
0.6


YJR049C
1.0
1.2
1.0
1.0
0.7
0.6
1.0
1.2
1.4
1.4


YLR078C
0.9
1.1
0.7
1.4

0.8
1.2
1.1
0.8
1.1


YNR037C
0.9
0.9
0.9
1.7
1.2
0.7
1.7
1.1
1.3
1.7


YOR028C
1.4
0.7
1.1
2.3
1.6
1.0
1.2
1.5
1.2
2.0











yeast
The level of expressed mRNA in the absence of chemical substance
















genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity



















YKR076W
18.6
1.5
5.1
14.7
3.2
9.6
1.8
2.7
0.27


YNL335W
1.1
0.8
0.9
4.6
1.7
1.0
1.2
1.1
0.22


YBR173C
2.5
1.7
3.8
3.0
15.4
2.1
0.9
1.6
1.15


YFL022C
1.2
0.6
0.6
3.1
1.1
1.3
0.9
0.8
1.07


YGL158W
0.2
1.3
1.0
2.3
2.3
8.2
0.8
1.1
0.18


YHR139C
3.5
1.6
7.0
2.5
1.9
17.1
1.4
1.3
0.34


YGR213C
1.6
10.6
30.4
1.0
6.5
5.2
12.8
8.5
0.22


YKL165C
0.3
2.4
3.2
0.8
2.1
1.2
0.9
1.0
1.08


YBL005W-A
0.8
1.6
2.9
1.4
0.9
1.1
1.3
1.0
0.48


YBL041W
1.6
1.6
2.6
2.0
1.3
2.3
1.3
2.0
3.03


YBL078C
4.6
3.1
5.0
3.6
2.5
4.4
1.8
2.8
0.65


YCL020W
1.3
1.5
3.0
1.7
2.5
1.3
0.9
1.3
1.46


YDL007W
1.3
1.1
2.4
1.4
1.4
0.8
0.8
1.5
2.43


YDL097C
1.5
1.3
4.0
1.4
1.1
1.1
1.0
1.3
2.06


YDL126C
1.4
1.3
4.3
0.6
1.7
0.7
0.9
0.9
3.24


YER012W
1.9
1.5
2.9
4.6
1.7
2.2
1.5
1.3
1.84


YFR010W
1.5
1.2
3.7
1.1
1.5
1.3
0.9
1.4
1.89


YFR024C
1.9
1.5
2.8
1.2
0.9
1.9
1.0
1.4
1.06


YGL048C
1.5
1.3
2.5
1.2
1.0
1.6
1.4
2.0
3.07


YGL141W
0.6
1.4
3.6
1.2
1.5
1.2
1.4
1.2
0.44


YGL180W
1.3
1.4
2.6
1.0
1.3
1.7
1.0
1.1
0.28


YGR048W
1.1
1.1
2.5
1.3
0.8
1.1
0.9
1.2
0.93


YGR135W
1.6
1.2
2.8
2.6
1.5
1.5
1.0
1.9
3.10


YGR201C
1.6
1.9
8.6
1.6
0.5
14.4
1.4
2.1
0.60


YHL030W
1.1
1.1
3.8
1.0
2.0
0.5
0.8
0.9
0.66


YHR166C
0.6
1.7
6.9
1.2
0.9
1.1
1.4
1.5
1.35


YJR069C
0.9
1.1
3.9
0.6
0.4
0.8
1.0
0.9
1.73


YKL073W
0.5
1.5
3.3
0.7
1.6
1.0
1.2
1.5
1.29


YKL103C
2.8
1.3
3.8
2.0
2.1
1.2
1.9
2.2
0.56


YLR080W
1.9
0.8
3.6
1.2
0.7
3.0
1.6
2.2
0.41


YLR107W
0.8
1.0
2.9
1.6
1.1
1.6
1.8
2.4
0.94


YLR121C
2.2
1.1
4.0
1.2
10.7
1.5
2.7
1.4
0.30


YLR336C
0.5
1.9
4.6
0.6
0.8
1.3
1.5
1.0
0.71


YLR370C
1.0
1.2
3.1
1.9
1.5
1.6
1.6
2.0
1.41


YLR423C
1.0
1.7
3.9
1.2
1.3
1.9
1.2
1.6
0.34


YML092C
2.5
1.2
2.3
1.6
1.4
2.2
1.3
1.5
1.72


YML130C
1.9
2.3
5.8
1.3
2.4
0.8
1.2
1.2
1.59


YMR214W
0.7
1.0
2.4
1.1
4.8
0.7
1.1
1.0
0.88


YMR297W
2.5
1.2
4.2
0.5
2.4
1.9
1.1
1.4
4.10


YNL036W
1.7
1.4
3.3
5.1
1.6
1.3
1.4
1.9
2.04


YOL005C
1.6
1.2
2.9
1.2
0.9
1.0
1.2
1.2
1.71


YOR134W
1.9
2.8
4.4
1.3
1.6
7.7
2.2
4.6
0.28


YOR362C
1.3
1.3
2.5
1.4
1.0
1.5
1.1
1.8
2.55


YAR009C
0.9
1.3
2.0
1.0
2.1
0.6
0.8
1.2
7.11


YBL101C
0.8
1.1
3.5
0.9
2.7
1.4
1.0
1.1
0.39


YBR046C
2.9
1.2
2.0
1.3
2.1
3.0
1.2
2.0
0.63


YBR139W
2.3
1.2
2.7
1.1
5.6
2.3
1.2
2.0
1.21


YBR170C
1.5
1.2
2.7
1.3
1.9
1.3
1.1
1.4
0.72


YBR177C
0.6
1.2
3.1
1.3
1.4
0.4
0.8
0.9
0.76


YBR212W
1.1
0.9
2.2
0.7
1.0
1.5
1.1
1.0
0.95


YBR239C
0.7
1.1
1.9
1.1
1.0
2.7
1.0
0.9
0.31


YCL033C
1.9
1.6
2.0
1.8
0.8
3.6
2.0
2.0
1.14


YCR062W
1.2
1.3
2.2
1.0
2.3
1.1
1.1
1.0
0.41


YCR067C
1.2
0.9
2.0
0.9
2.1
1.4
1.1
0.9
0.62


YDL020C
1.9
1.1
3.4
1.2
1.5
1.8
1.5
1.7
1.36


YDR168W
1.5
1.2
2.4
1.4
1.9
1.4
1.2
1.4
1.28


YDR169C
0.9
0.9
1.9
0.9
1.4
0.9
1.4
1.1
0.40


YDR188W
0.9
0.9
1.7
0.7
1.3
0.9
0.7
0.8
1.78


YDR264C
0.9
1.1
2.1
0.7
2.3
1.5
1.2
1.4
1.63


YDR304C
1.2
1.3
2.3
1.7
1.0
4.0
1.6
1.8
2.23


YDR403W
1.0
1.0
2.0
1.1
0.9
0.9
0.9
1.0
0.35


YDR427W
1.2
1.1
2.1
1.0
1.3
1.1
1.0
1.5
2.37


YEL012W
2.2
1.2
2.2
1.9
1.1
2.5
1.5
2.2
0.74


YER009W
1.4
1.1
2.0
1.6
0.9
1.5
2.0
2.1
3.35


YER021W
1.3
1.0
1.8
1.3
0.8
1.4
0.8
1.5
2.02


YER094C
1.3
1.1
2.1
1.5
0.8
1.5
1.3
1.8
3.01


YER177W
1.9
1.1
2.2
0.9
1.4
1.0
0.9
2.0
5.81


YFL029C
2.1
1.1
1.8
1.9
1.3
1.2
1.2
1.4
0.49


YFL038C
1.7
1.1
2.1
1.5
1.5
2.1
1.2
1.6
2.31


YFR004W
1.3
1.2
2.0
2.1
1.1
1.3
1.0
1.4
2.44


YFR050C
1.4
1.5
2.1
1.6
1.5
1.5
1.1
1.7
1.70


YGL011C
1.5
1.0
2.1
3.0
1.3
1.7
1.3
1.5
1.78


YGL094C
0.6
0.8
2.3
0.9
1.9
1.0
1.0
0.9
0.51


YGL150C
0.4
0.8
2.4
1.0
1.3
0.9
0.9
0.8
0.62


YGL207W
0.7
0.7
2.5
0.8
1.2
0.7
0.9
0.8
0.88


YGR232W
1.3
1.1
2.4
2.1
0.9
1.8
1.3
1.2
0.96


YGR248W
2.3
1.1
2.0
1.5
1.5
7.9
1.0
1.5
0.52


YGR253C
2.4
1.1
3.4
1.8
1.1
1.8
1.5
2.1
2.01


YHR027C
1.1
1.0
2.1
0.7
1.5
0.9
0.8
1.0
2.06


YHR161C
1.2
1.0
1.8
1.0
1.4
1.7
1.4
1.5
0.86


YHR169W
0.4
1.1
3.3
1.1
0.6
1.0
1.6
1.3
0.81


YIL010W
1.4
1.4
2.3
1.7
1.1
1.7
1.5
1.5
0.70


YIL034C
1.6
1.0
2.6
1.1
1.0
1.7
1.2
1.5
0.99


YIL142W
1.7
1.1
1.8
1.0
1.3
0.7
0.9
0.8
1.84


YIR039C
3.8
1.4
2.9
1.9
2.0
4.2
1.2
1.1
0.45


YJL001W
1.5
1.6
2.9
2.5
1.2
1.8
1.0
1.6
3.00


YJL035C
0.8
1.1
2.4
1.6
0.7
0.6
1.0
1.0
0.82


YJL053W
1.6
1.1
1.9
1.3
1.1
1.7
1.3
1.6
0.80


YJL164C
1.5
1.0
2.1
0.9
0.8
2.1
1.3
1.7
1.04


YJL210W
2.4
1.0
2.2
0.9
0.8
2.3
0.9
1.0
0.70


YJR117W
1.0
1.2
2.8
0.8
2.2
0.7
0.8
0.9
1.34


YKL007W
1.8
1.3
2.5
0.7
1.0
1.0
1.4
1.3
1.13


YKL117W
1.6
1.0
2.4
1.6
1.6
1.8
1.2
1.8
3.73


YKL193C
1.7
0.9
2.1
1.2
1.2
2.4
1.2
2.3
0.71


YLR120C
1.2
1.6
4.8
0.8
2.7
1.7
3.5
2.9
1.53


YLR136C
1.2
1.3
2.9
0.7
2.1
1.2
1.8
1.4
0.41


YLR178C
3.7
2.2
7.5
2.8
2.3
10.6
2.0
3.6
1.03


YLR327C
5.0
1.4
2.8
1.5
0.8
2.8
3.3
5.3
2.23


YLR356W
3.1
1.5
2.5
2.2
2.8
0.9
1.1
1.0
0.41


YLR362W
1.5
0.8
2.4
1.2
1.3
1.9
1.2
1.3
0.35


YLR429W
0.9
1.1
2.3
0.7
1.5
1.0
1.0
0.9
0.86


YMR004W
2.5
1.0
2.2
2.2
1.3
1.3
0.9
1.3
0.52


YMR219W
1.5
1.5
2.1
0.5
1.7
0.8
1.1
0.9
0.23


YMR275C
1.1
0.7
2.1
0.8
1.7
1.0
0.9
0.7
0.79


YMR314W
1.8
1.0
2.6
1.0
1.2
1.6
1.3
1.6
1.67


YNL006W
1.1
0.7
2.3
0.8
0.7
0.9
1.0
1.3
1.20


YNL007C
1.3
0.7
2.1
0.4
0.8
0.5
1.1
1.0
3.62


YNL093W
1.6
1.1
2.2
1.1
0.6
4.9
3.0
3.1
0.32


YNL333W
2.0
1.0
2.2
1.9
1.0
1.4
1.4
1.1
0.49


YNR010W
1.4
0.8
2.8
1.3
0.8
1.2
1.7
2.3
0.37


YNR069C
2.5
1.2
3.4
2.1
1.0
0.8
1.1
0.9
0.18


YOL164W
1.0
1.1
3.4
1.3
1.0
1.1
1.1
1.3
0.45


YOR036W
1.3
1.2
2.1
1.2
1.2
1.3
1.6
1.7
0.98


YOR117W
1.2
2.5
2.3
1.0
1.4
1.2
1.4
0.9
1.42


YOR124C
1.2
0.9
2.1
0.8
1.3
0.9
1.0
1.0
0.65


YOR132W
1.3
0.7
2.5
0.7
1.5
1.6
1.2
1.6
0.46


YOR157C
1.6
1.3
2.4
2.2
1.9
0.9
1.2
1.2
1.23


YOR185C
1.2
1.5
2.2
2.1
1.0
2.2
0.9
1.1
1.67


YOR259C
1.0
0.8
1.8
1.2
1.3
1.4
0.9
1.5
2.33


YOR261C
2.1
0.9
2.5
1.8
1.3
2.0
1.0
1.9
2.80


YOR288C
1.4
1.4
2.4
0.8
1.8
1.4
1.5
1.6
0.79


YPL109C
−0.2
0.9
1.8
1.3
1.3
1.9
1.2
1.2
0.21


YPL149W
1.2
0.9
2.3
1.0
0.8
1.2
2.2
2.9
1.39


YPL154C
1.8
1.5
3.1
0.8
4.0
1.8
1.6
2.0
3.78


YPR103W
0.9
1.2
2.8
1.8
1.0
1.1
1.2
1.5
1.93


YPR108W
1.8
1.0
2.6
1.0
1.3
1.2
1.0
1.3
2.25


YCL027W
0.9
0.8
1.1
1.2
3.6
1.1
0.7
0.8
0.30


YDR055W
2.2
1.4
3.1
0.9
5.7
3.4
2.0
1.9
1.55


YEL042W
1.6
1.0
0.4
0.6
4.8
0.6
0.7
0.8
1.21


YGR136W
1.3
1.2
1.7
1.1
2.6
2.2
1.3
1.8
1.42


YHR142W
1.1
1.3
1.2
1.2
4.8
1.0
1.3
1.3
1.17


YJL073W
0.5
1.0
1.6
1.1
2.6
0.8
1.1
1.0
0.43


YJR004C
0.7
0.8
0.3
0.7
3.2
0.3
0.4
0.4
2.12


YKL039W
1.0
0.9
1.9
0.8
3.1
1.5
1.2
1.3
1.13


YLR250W
1.4
1.0
1.2
2.5
2.6
2.1
1.4
2.2
2.90


YOR181W
1.0
0.8
1.2
0.9
3.4
1.0
1.1
0.6
0.39


YOR198C
1.4
1.5
1.8
1.1
3.8
0.8
1.1
1.5
1.76


YPL089C
0.9
0.7
1.3
0.8
2.6
0.9
1.5
1.1
0.37


YBR214W
3.2
1.2
2.1
0.9
5.1
1.3
1.1
1.2
0.51


YDR085C
1.7
1.6
1.1
1.6
3.1
2.3
1.3
1.8
0.37


YDR259C
1.2
1.0
2.0
1.5
2.9
0.9
1.0
0.8
0.28


YDR388W
1.6
0.8
1.7
0.6
2.6
1.0
1.2
1.3
0.99


YDR432W
0.6
0.7
1.4
0.5
2.6
0.6
0.7
0.7
2.38


YDR481C
1.2
0.9
1.5
0.9
3.5
1.3
1.2
1.4
1.43


YDR510W
1.6
1.4
2.0
1.9
2.2
1.5
1.1
1.5
1.57


YGR189C
1.5
1.3
1.2
0.9
9.3
0.6
2.3
1.7
1.51


YIL123W
1.2
0.8
0.4
0.3
4.8
0.7
1.3
1.0
1.67


YIL140W
0.9
1.0
0.5
0.9
3.3
0.6
0.7
1.0
0.62


YKL096W
3.5
0.3
0.1
0.5
2.3
0.4
0.5
0.7
2.04


YLR391W
1.4
1.0
0.9
0.5
3.9
1.3
1.4
0.9
1.72


YMR094W
1.0
0.9
1.4
2.8
6.6
1.0
1.0
1.0
0.23


YMR104C
1.1
1.0
1.5
1.1
2.5
2.3
2.8
1.9
0.51


YMR276W
1.9
1.2
1.9
1.2
3.3
0.9
1.2
0.7
0.47


YOL013C
1.4
1.1
1.8
0.9
2.7
1.3
1.1
1.4
0.65


YOR355W
1.2
0.9
1.1
0.6
3.2
0.8
0.8
0.9
0.98


YCR071C
1.1
1.1
1.3
1.7
1.1
1.5
1.2
1.3
0.96


YDL008W
0.9
1.2
2.0
2.2
0.7
1.3
1.5
1.6
0.95


YDR115W
1.2
0.9
1.1
1.5
0.8
2.2
1.2
1.4
1.50


YER130C
0.9
1.0
1.6
0.8
1.1
0.7
3.0
2.5
1.36


YMR226C
1.4
1.1
1.6
1.6
2.0
1.7
1.6
2.0
2.03


YOR383C
1.4
1.1
1.2
0.6
1.1
3.0
1.4
1.1
0.68


YAR010C
0.9
1.0
1.4
1.0
1.8
0.7
1.5
1.0
4.69


YBL043W
1.5
0.9
1.8
1.9
1.8
2.3
2.3
1.8
0.47


YCR004C
1.9
0.8
1.3
3.7
0.8
4.9
1.4
3.5
3.02


YCR088W
1.0
1.3
1.9
0.9
2.8
0.7
1.4
0.9
0.47


YDL238C
1.1
0.9
2.0
1.2
1.3
1.7
1.1
1.3
0.35


YDR084C
0.7
0.7
1.0
1.0
3.9
1.0
2.0
1.3
1.12


YDR104C
1.0
1.1
1.6
1.4
1.4
0.9
0.9
1.0
0.34


YDR315C
1.1
0.6
1.6
1.4
1.5
1.5
1.2
1.2
0.48


YDR358W
1.0
1.1
3.2
1.2
0.9
2.2
1.9
1.9
0.50


YEL066W
1.9
0.8
1.6
1.9
1.0
1.9
1.0
1.1
0.64


YER039C
1.2
0.9
2.1
1.2
1.2
1.8
1.7
1.1
0.42


YER107C
0.7
0.7
0.9
1.1
0.7
0.9
1.1
1.2
0.92


YFL028C
1.3
1.1
1.4
1.6
0.8
1.9
1.2
1.5
1.28


YFL043C
1.1
0.9
1.5
1.5
1.1
2.0
1.5
1.2
0.38


YGL229C
1.1
1.1
1.7
1.0
0.2
1.8
1.1
0.9
0.44


YGR257C
1.2
0.9
2.0
0.9
1.3
1.3
1.1
1.3
0.84


YHR004C
0.8
0.9
1.1
0.8
1.2
2.4
1.4
1.6
0.84


YHR071W
1.8
0.8
2.3
1.6
3.0
1.7
2.6
1.0
0.79


YJL089W
0.6
1.2
1.8
1.8
6.4
1.2
1.2
1.1
0.21


YJL116C
2.9
1.1
4.3
2.6
1.0
1.3
1.2
0.7
1.01


YJR086W
1.0
0.8
0.9
2.2
2.0
1.4
1.4
1.6
1.24


YKL008C
1.5
1.5
1.7
0.8
1.3
2.1
1.4
1.9
2.11


YKL013C
1.1
0.7
1.3
1.4
1.2
1.5
1.6
1.7
1.55


YKL041W
1.2
0.8
1.3
1.3
1.0
2.5
1.1
1.3
0.91


YKL139W
1.4
0.8
1.6
1.0
1.0
1.3
1.9
0.8
0.62


YKR014C
1.1
1.1
1.5
1.8
1.4
2.4
1.0
1.7
2.05


YLR093C
1.0
1.0
1.3
1.3
0.9
2.4
1.7
3.2
1.90


YLR118C
1.2
1.0
1.4
1.5
0.8
3.5
1.3
1.9
1.17


YLR251W
4.1
0.8
1.7
1.3
0.8
2.5
2.1
3.8
0.78


YMR027W
1.1
0.9
2.4
0.9
4.0
0.8
1.3
1.2
4.05


YMR262W
1.3
0.8
1.7
0.9
0.3
1.0
1.0
1.2
0.65


YNL214W
0.6
0.8
1.2
1.7
0.9
2.0
1.1
1.2
0.47


YOR149C
1.0
0.9
1.3
0.9
1.3
1.1
1.0
1.2
0.76


YOR165W
1.3
0.7
0.9
0.8
0.8
1.0
0.9
1.0
1.03


YOR285W
2.3
0.9
2.1
1.6
2.0
2.9
2.3
3.3
2.62


YOR367W
1.4
0.5
0.8
1.5
1.1
1.3
1.4
1.4
0.60


YPL018W
1.3
1.1
2.2
1.3
0.9
0.8
1.3
0.8
0.22


YPL203W
1.5
0.9
1.5
1.0
0.6
2.3
1.3
1.7
0.79


YPL255W
0.7
0.6
0.6
0.7
0.6
0.7
0.8
0.7
0.55


YPR073C
0.9
0.8
1.4
1.5
0.8
1.8
1.4
1.8
1.55


YDR518W
1.0
1.5
1.8
0.8
2.5
1.7
1.4
1.6
0.93


YOR381W
2.6
1.1
1.7
0.8
0.6
2.5
0.8
0.9
0.38


YBR109C
1.5
1.4
2.0
2.0
1.4
1.9
1.4
1.9
2.15


YBR201W
1.1
1.7
1.9
1.1
1.6
1.5
1.8
1.6
0.75


YDR041W
1.2
0.8
0.9
1.4
1.0
2.4
1.5
2.5
1.85


YER136W
1.7
0.9
1.3
0.8
1.2
1.6
1.3
1.7
2.31


YER159C
1.6
0.9
0.9
1.1
2.2
1.1
1.6
1.9
0.99


YJL030W
1.4
1.0
1.4
2.1
1.5
1.9
1.3
1.5
0.87


YJR029W
0.6
1.0
2.1
1.1
1.8
0.7
0.8
1.1
5.84


YJR099W
1.3
0.7
1.5
2.1
0.5
2.0
1.1
1.7
0.94


YJR122W
2.4
0.9
1.3
1.4
0.8
1.9
1.0
1.1
0.43


YJR125C
1.1
0.9
1.5
1.1
1.3
2.0
1.2
1.4
0.90


YKL190W
1.5
0.9
1.3
1.7
1.4
1.8
1.3
1.3
1.14


YLL051C
0.7
1.1
1.3
0.8
1.2
0.8
1.0
1.0
0.81


YLR090W
1.0
0.8
1.7
1.0
0.8
1.9
0.8
1.0
0.67


YMR051C
1.1
0.9
1.3
1.2
1.7
1.0
1.8
1.2
3.91


YMR139W
1.3
0.9
1.6
1.3
0.9
2.3
1.1
2.0
0.89


YNL015W
2.1
2.8
3.9
1.6
1.4
5.3
3.0
5.2
1.03


YNL079C
1.3
1.2
1.8
1.0
1.5
1.4
1.0
1.9
3.26


YNL223W
1.3
1.3
2.0
1.2
1.0
2.1
1.0
1.5
0.34


YNR007C
0.7
0.9
1.5
1.5
0.6
2.0
1.4
1.6
0.49


YNR035C
1.5
1.1
1.7
1.0
1.3
1.6
1.4
1.8
1.60


YOL016C
1.3
1.4
3.0
0.7
0.5
1.6
4.3
3.8
2.10


YOL104C
1.2
0.8
0.6
2.2
1.3
0.5
1.1
0.9
0.32


YPR107C
1.2
0.7
1.4
1.7
1.0
1.4
1.2
1.5
0.81


YOL152W
5.9
0.8
0.5
0.4
0.8
1.2
1.1
1.2
0.91


YAL007C
2.0
1.3
2.0
1.3
2.5
0.8
1.2
1.5
1.74


YDL043C
3.9
0.9
0.8
1.2
0.8
1.2
0.8
0.8
0.78


YDL212W
2.0
0.8
0.5
1.0
1.1
0.9
1.1
1.7
4.27


YDR183W
1.8
1.1
1.4
1.9
1.4
1.3
0.8
1.0
0.61


YGL089C
2.3
0.4
0.2
1.4
0.9
0.2
0.3
0.6
3.00


YGL096W
1.7
1.1
1.2
1.4
0.8
1.7
1.1
1.1
0.54


YGR006W
1.6
0.8
1.4
1.1
1.2
1.5
0.9
1.0
0.40


YHL034C
2.2
0.8
1.6
1.0
1.4
1.6
1.2
1.5
2.11


YHR163W
2.9
0.7
1.1
1.5
0.7
1.2
1.1
1.2
1.71


YIR024C
6.3
1.1
1.6
2.6
0.9
2.2
0.9
1.4
0.75


YKL070W
10.4
0.6
1.0
2.2
0.8
0.9
1.0
0.9
0.29


YLL050C
2.3
0.9
1.8
1.2
1.6
1.3
1.2
2.1
3.43


YLR220W
2.4
0.7
0.5
1.4
0.7
1.1
0.8
0.8
2.28


YLR390W
1.9
1.0
1.1
1.1
0.5
2.0
1.0
0.9
0.51


YOL044W
2.1
0.7
1.3
1.1
0.6
1.3
1.6
1.9
0.65


YOL147C
2.8
0.7
0.8
0.9
0.8
2.4
2.0
1.7
1.09


YDR069C
0.8
0.7
1.3
1.2
1.0
1.3
1.0
1.3
0.33


YER131W
1.0
0.9
0.2
0.8
0.9
0.4
0.9
0.9
5.32


YGR044C
2.1
0.8
1.4
1.0
0.5
3.3
1.1
2.6
1.43


YMR240C
1.4
0.6
0.8
1.1
1.0
1.0
1.1
1.1
0.39


YBR105C
1.1
1.2
1.1
1.7
1.4
1.3
1.3
1.1
0.96


YBR182C
1.5
1.3
1.2
1.2
3.1
1.1
3.4
1.6
0.41


YBR186W
0.9
0.8
0.7
1.1
0.9
1.2
0.7
1.0
0.31


YEL052W
1.7
1.1
1.5
1.1
0.7
2.1
0.9
1.0
0.90


YER098W
1.4
1.0
1.1
1.3
0.9
1.7
1.2
1.5
0.35


YGL240W
0.9
0.8
1.7
1.3
1.1
1.0
1.2
0.8
0.48


YGR067C
1.0
0.7
1.0
0.9
1.2
1.7
1.2
1.0
0.11


YGR133W
1.6
0.9
1.2
1.4
1.0
1.5
1.0
1.0
0.35


YHR124W
1.1
1.2
1.7
2.7
0.8
1.8
1.3
1.1
0.24


YJL103C
1.5
0.8
1.4
1.0
1.3
0.9
1.4
1.2
0.44


YJR036C
1.1
0.9
1.1
1.3
1.8
2.0
0.9
1.2
0.31


YLR216C
1.8
0.7
1.2
1.1
1.2
1.5
1.2
1.3
1.44


YLR389C
0.9
0.8
1.9
0.8
1.0
1.4
1.0
1.0
0.60


YNL128W
0.9
0.9
1.4
1.4
1.1
0.6
0.9
0.9
0.21


YOL133W
1.5
0.6
1.0
1.4
1.3
2.0
1.3
1.3
0.87


YOR133W
1.3
0.8
1.3
1.1
1.8
1.3
1.2
1.2
0.26


YOR227W
1.2
1.0
1.7
1.1
3.7
2.2
0.8
1.3
0.35


YPR015C
1.0
0.7
1.5
1.5
1.6
2.0
1.0
1.0
0.32


YPR086W
1.3
0.8
1.0
1.0
1.3
1.4
1.2
1.2
1.37


YBL056W
0.7
0.9
2.7
0.9
1.0
1.7
1.1
1.5
2.49


YBR026C
1.6
1.2
1.5
1.5
0.7
0.5
0.8
0.9
0.59


YBR123C
1.1
1.0
1.4
1.1
1.0
1.2
0.8
1.0
0.62


YDR099W
1.1
0.9
1.5
0.9
1.9
1.4
1.2
1.7
3.51


YDR177W
1.3
1.2
1.7
2.4
0.8
1.3
1.3
1.5
1.77


YDR392W
1.2
0.8
1.4
1.3
1.1
1.4
1.0
1.2
0.63


YDR394W
1.8
0.6
1.0
1.2
1.1
1.0
1.1
0.8
0.97


YER184C
1.3
0.8
1.6
1.4
1.4
1.2
1.6
2.3
0.29


YFL059W
1.5
1.2
2.3
2.4
0.9
1.6
1.3
1.1
0.57


YGL185C
1.5
1.5
1.7
1.5
0.9
15.8
1.3
1.6
0.23


YHL019C
1.3
0.8
0.8
0.8
1.2
1.3
1.0
1.0
0.55


YHR012W
1.5
0.9
1.7
1.7
1.0
1.0
1.2
1.4
1.11


YHR028C
1.4
0.7
0.6
1.1
1.1
0.7
1.0
1.0
0.92


YHR109W
0.7
1.0
1.4
1.5
0.9
1.3
0.9
1.1
0.22


YHR156C
0.6
0.7
1.0
1.9
1.2
1.4
0.9
1.3
0.47


YIL159W
0.8
0.9
1.5
2.0
1.0
0.7
0.9
0.8
0.29


YJL154C
0.5
0.9
1.6
0.8
1.2
1.2
1.2
1.1
0.62


YJR110W
1.2
0.7
0.9
1.1
1.2
1.1
0.8
1.0
0.58


YKL025C
1.1
0.8
1.3
0.9
1.2
1.1
0.9
1.0
0.54


YKL171W
2.8
1.1
1.5
1.1
1.2
2.1
0.9
1.2
0.45


YKL196C
1.6
1.0
1.8
2.5
1.9
1.9
1.3
2.0
2.41


YKR068C
1.0
1.0
1.1
1.6
0.8
1.4
1.4
1.7
1.72


YLR144C
1.0
0.7
2.3
1.2
1.9
1.7
1.0
1.0
0.44


YML112W
1.0
1.0
1.3
1.8
0.8
0.9
0.8
0.9
0.49


YOL038W
2.0
0.9
1.8
2.1
1.7
1.6
1.1
1.4
1.29


YOR257W
1.0
0.7
0.8
1.5
0.7
1.6
1.1
1.6
0.68


YOR265W
1.3
0.8
1.8
2.5
1.2
1.1
1.0
1.2
0.93


YPL124W
0.9
0.7
0.9
1.6
0.6
0.8
1.3
1.2
0.41


YPR125W
0.9
1.1
1.9
1.6
2.0
0.6
0.8
0.7
0.73


YPR168W
1.2
0.5
1.0
1.1
1.2
1.3
0.9
0.8
0.29


YPR180W
0.5
0.7
1.3
1.2
1.3
1.0
1.0
1.4
0.61


YPR193C
0.1
0.9
1.6
1.6
0.9
1.6
1.1
0.9
0.17


YBR045C
0.4
1.3
1.3
1.0
2.0
0.8
1.1
0.9
1.29


YBR128C
1.3
0.7
1.3
1.4
1.4
2.0
1.2
1.8
0.44


YCL055W
1.4
0.9
0.9
1.8
1.5
0.7
0.8
1.1
0.66


YCR019W
2.0
1.0
1.6
1.2
0.7
1.4
1.0
1.0
0.45


YDL065C
1.4
0.6
0.7
1.4
1.3
1.5
1.1
1.2
1.08


YDL143W
1.3
1.1
1.9
0.9
1.4
0.9
0.8
0.8
1.86


YDL197C
1.1
0.8
1.4
1.1
1.3
0.9
1.3
0.8
0.31


YDL230W
0.9
0.6
1.3
1.0
1.4
1.7
1.0
1.2
0.42


YDR212W
1.8
0.8
2.0
1.0
1.2
0.7
0.6
1.0
2.13


YDR257C
1.3
0.7
1.0
1.0
1.3
1.0
1.1
0.8
0.62


YDR329C
1.0
0.8
1.1
1.1
1.0
1.6
1.2
1.6
0.95


YDR488C
0.4
0.6
1.3
0.8
3.5
0.7
0.9
0.9
0.32


YDR505C
1.0
0.7
1.6
0.9
1.1
1.6
1.0
1.5
0.84


YDR506C
1.1
0.9
0.3
0.5
0.9
0.4
0.6
0.5
1.90


YDR515W
1.0
0.8
0.7
0.8
1.3
0.5
0.7
0.5
1.02


YEL005C
1.6
0.8
1.2
1.7
0.8
3.4
1.1
1.4
0.45


YER048C
1.6
0.8
1.1
1.0
0.6
1.8
1.3
1.6
1.08


YER078C
1.3
1.0
1.5
1.0
0.9
1.0
0.9
0.9
0.49


YER089C
1.2
0.7
1.3
0.6
1.0
0.8
0.7
0.6
0.75


YER100W
1.1
0.8
0.7
0.8
1.0
1.1
1.1
0.7
0.95


YFR051C
1.3
1.2
1.5
0.8
3.0
0.8
1.1
0.9
0.53


YGL093W
1.1
0.6
0.7
0.8
1.4
1.0
0.9
1.2
0.56


YGL105W
1.4
1.1
1.0
1.1
0.9
1.0
0.8
0.9
3.01


YGL166W
1.0
1.1
1.9
1.1
0.9
1.2
2.1
1.9
0.73


YGL215W
0.8
0.7
1.0
0.8
1.0
1.2
0.7
0.9
1.31


YGL216W
0.5
1.0
1.4
1.0
1.1
0.8
1.1
0.9
0.37


YGL221C
1.4
1.1
1.7
1.7
0.7
1.3
1.1
1.4
1.64


YGR186W
1.0
0.6
1.1
1.1
1.3
1.4
1.3
1.2
0.79


YGR270W
0.7
0.8
1.3
0.9
1.6
1.0
0.9
0.9
0.51


YGR274C
0.9
0.7
1.1
0.8
1.2
0.7
1.1
1.0
0.62


YHR082C
0.9
0.7
1.7
0.9
1.4
0.7
1.1
0.9
0.60


YHR160C
−0.2
0.8
1.8
1.2
2.1
4.4
1.0
1.5
0.32


YHR171W
1.2
0.8
1.3
1.0
0.7
1.6
1.2
1.5
0.41


YHR205W
0.9
0.9
1.7
0.9
1.5
0.8
0.9
0.8
0.34


YIL062C
1.7
0.8
1.1
2.0
0.9
0.4
1.1
1.1
1.72


YIL075C
0.8
0.8
0.7
0.8
1.6
0.8
0.8
0.8
1.54


YIR009W
1.1
0.7
0.8
1.6
1.1
1.0
1.7
1.0
0.48


YIR018W
1.2
1.1
1.5
1.2
1.5
1.0
1.6
1.1
0.44


YJR091C
1.8
0.8
1.4
0.8
1.4
0.7
1.2
0.9
0.57


YKL079W
1.3
0.9
1.2
0.9
1.1
1.6
1.1
1.2
0.64


YKR102W
3.3
0.8
2.7
1.8
1.1
1.5
1.5
0.9
0.19


YLL054C
0.5
0.7
1.7
1.2
0.9
0.9
1.0
1.0
0.33


YLR200W
1.1
0.9
1.3
2.3
0.9
1.2
1.1
1.5
1.12


YLR248W
1.0
0.7
1.2
0.9
1.2
1.7
1.1
1.7
1.58


YLR266C
1.1
1.0
1.3
1.0
0.8
1.7
0.8
1.4
0.74


YML088W
0.5
1.0
1.3
1.1
1.4
0.8
0.8
0.8
0.58


YMR091C
0.9
0.8
0.9
1.5
0.9
1.3
0.9
1.2
1.03


YMR110C
1.6
0.9
1.8
0.8
0.9
2.7
1.5
2.5
1.63


YMR255W
1.2
0.9
1.1
1.6
1.0
1.3
1.5
2.0
0.97


YNL039W
0.4
0.9
0.8
0.8
1.3
1.3
0.9
1.1
0.61


YNL077W
1.0
0.7
1.5
0.5
0.3
0.6
1.3
1.0
0.78


YNL083W
0.9
0.9
1.2
0.9
0.8
1.8
0.8
1.1
0.37


YNL147W
1.2
0.8
1.0
2.0
1.2
1.7
1.0
1.6
1.32


YNR006W
0.8
0.9
1.6
0.9
1.2
1.1
1.8
1.2
0.40


YNR034W
1.3
0.9
1.4
0.9
1.1
2.3
0.7
1.1
0.64


YNR047W
0.6
0.9
1.5
0.9
1.2
1.5
0.9
1.0
0.44


YOR023C
0.9
1.1
1.9
0.9
1.6
0.8
1.1
0.8
0.37


YOR058C
1.4
0.7
1.7
1.7
1.1
1.6
0.9
1.0
0.31


YOR069W
2.8
0.9
1.1
1.3
1.4
1.5
0.8
1.1
0.69


YOR229W
0.7
0.8
1.3
1.0
1.2
0.9
0.9
1.0
0.58


YOR256C
1.7
0.7
1.6
1.1
1.1
1.5
1.2
1.5
0.53


YPL020C
1.1
0.9
1.1
1.1
1.6
1.2
1.3
1.4
0.91


YPL105C
0.6
0.7
1.0
0.6
1.1
0.5
0.8
0.6
0.80


YPR066W
0.9
0.8
1.4
1.2
0.7
1.6
1.1
1.2
0.41


YPR081C
0.9
1.0
1.4
1.1
1.3
1.8
0.9
1.3
0.34


YPR140W
0.8
0.8
1.3
1.4
1.7
2.4
0.8
1.3
0.47


YPR155C
0.9
0.9
1.3
1.2
0.5
3.4
0.8
1.6
0.40


YPR185W
0.9
0.8
1.7
1.0
1.1
1.3
1.3
1.1
0.68


YBR076W
0.8
0.9
1.9
1.2
1.1
0.5
1.4
1.2
0.36


YDR373W
1.7
0.5
1.0
2.1
1.6
1.4
1.2
1.6
1.08


YFR014C
1.8
0.9
1.3
1.0
0.6
2.3
1.2
2.9
0.94


YHR136C
2.0
1.2
0.3
1.7
0.5
1.3
1.6
2.5
1.33


YIL129C
1.5

1.9
0.9
1.0
1.0
1.3
0.8
0.25


YMR077C
1.5
0.9
0.8
1.6
1.7
2.3
0.9
1.3
0.59


YBR264C
1.0
1.0
0.9
1.6
1.1
1.8
0.9
1.3
0.61


YPL177C
1.4
0.8
0.8
1.3
0.6
1.9
1.2
1.1
0.75


YGL056C
0.0
1.1
0.8
1.1
1.2
1.5
0.9
1.1
0.47


YBL101W-A
1.2
1.1
2.0
1.5
2.1
1.1
1.3
1.2
1.24


YER072W
1.7
1.1
0.6
1.5
0.9
1.1
1.7
1.7
1.69


YMR112C
0.9
1.0
0.9
1.8
0.9
1.4
1.1
1.6
0.57


YJR058C
1.2
0.7
0.8
1.8
0.8
1.2
1.3
1.2
1.00


YML055W
1.4
1.0
1.7
1.9
0.6
1.4
1.2
1.5
1.08


YDR080W
1.2
1.0
2.0
1.1
1.2
1.7
1.2
1.3
0.68


YNR030W
1.2
0.8
1.5
0.6
1.1
0.4
0.9
0.8
1.19


YNL196C
0.7
1.0
2.2
1.2
0.8
2.1
1.1
1.2
0.50


YOR148C
1.3
0.9
1.4
1.4
1.0
1.3
1.0
1.3
1.08


YER029C
0.8
0.9
0.9
1.4
1.1
1.7
0.9
1.3
1.20


YLR360W
0.9
0.9
0.7
1.1
0.8
2.1
1.2
1.4
0.53


YGR239C
1.4
1.0
1.0
1.4
1.3
1.1
1.1
1.3
0.49


YDL229W
1.6
0.9
1.0
1.3
1.2
1.0
1.2
1.1
0.76


YJR027W
1.1
0.8
1.3
1.1
2.3
0.7
0.7
1.1
4.88


YKL198C
1.4
0.7
1.9
6.6
2.6
0.7
1.0
0.8
0.17


YBR031W
0.9
1.0
0.3
0.4
0.9
0.7
1.0
0.8
7.58


YBR118W
1.0
0.8
0.8
0.7
1.6
0.6
1.2
0.9
8.91


YCR106W
1.2
0.8
1.2
0.8
1.3
1.2
1.1
1.2
0.76


YDR012W
0.9
1.2
0.2
0.4
0.8
0.7
1.0
0.7
7.07


YDR134C
1.9
0.6
0.4
0.5
0.8
0.9
0.7
1.1
5.84


YDR276C
1.4
0.9
1.1
1.3
2.2
3.6
1.3
2.4
2.48


YGR279C
0.9
0.7
0.3
0.4
1.3
0.8
1.0
0.8
3.77


YJL059W
1.8
1.0
1.6
1.3
0.9
0.8
1.1
1.0
0.39


YKL056C
1.1
0.8
0.1
0.7
0.9
0.6
0.8
1.2
6.68


YKL097W-A
1.6
0.7
0.2
0.6
2.0
0.8
1.1
1.4
4.01


YNL209W
0.9
0.9
0.5
0.6
0.9
0.3
0.6
0.6
8.06


YNL307C
1.0
1.0
1.0
0.7
0.6
1.0
1.0
1.3
2.79


YPR028W
1.4
0.6
1.7
0.8
0.9
1.3
1.2
1.7
4.06


YPR149W
1.1
0.7
1.4
1.3
1.0
2.2
1.1
1.1
2.65


YAL016W
0.9
0.8
1.4
0.9
1.1
1.1
0.8
1.3
1.00


YBR283C
2.0
0.8
0.8
0.6
1.4
0.9
0.9
0.9
2.62


YBR286W
1.0
1.1
1.8
1.5
1.3
2.6
0.8
1.6
2.98


YCL008C
0.9
0.9
1.0
0.9
1.4
0.6
0.9
0.9
0.47


YCR069W
1.3
1.4
1.6
1.0
2.4
1.2
1.2
1.3
0.97


YDL061C
1.4
1.0
0.1
0.7
1.0
0.6
1.1
1.0
4.40


YDR151C
2.1
0.9
2.8
1.1
0.6
1.2
0.8
1.1
0.96


YDR382W
1.2
0.7
0.1
0.7
1.1
0.4
1.0
1.0
6.40


YDR385W
0.9
0.9
0.3
0.5
0.8
0.3
0.6
0.4
7.27


YDR407C
1.2
1.0
1.3
0.8
1.3
1.0
0.9
0.9
0.52


YGL206C
0.9
0.7
1.1
0.8
1.3
0.6
0.8
1.0
1.04


YGR172C
0.8
0.8
0.7
1.1
1.9
1.0
1.1
1.1
0.94


YIL015W
0.8
0.9
0.8
5.9
1.1
0.8
0.8
1.0
0.17


YIL018W
1.2
0.6
0.0
0.6
0.6
0.4
0.8
0.8
6.27


YJL138C
1.2
0.8
0.3
0.7
0.9
0.6
0.9
1.0
7.38


YJL191W
1.1
1.0
0.9
1.1
0.7
2.2
1.0
1.0
1.86


YJR047C
1.1
0.9
0.9
0.9
0.6
0.8
0.8
0.9
5.29


YJR119C
1.1
0.9
1.2
1.3
1.5
1.0
0.7
0.9
0.30


YJR123W
0.9
0.8
0.1
0.6
1.1
0.4
0.8
0.9
7.84


YJR145C
0.8
0.6
0.0
0.6
0.8
0.5
0.8
0.9
4.82


YLR110C
3.2
0.7
0.5
0.5
1.7
0.8
0.9
1.1
3.99


YLR264W
0.8
1.1
0.3
1.2
1.2
0.5
1.0
1.1
3.91


YLR340W
1.4
0.9
0.1
0.5
1.3
0.2
0.9
0.7
6.55


YLR388W
1.0
0.6
0.1
0.8
0.6
0.5
0.8
1.0
4.48


YMR092C
1.2
0.9
1.7
0.8
1.1
1.2
0.9
1.3
1.43


YMR101C
−0.3
0.7
0.8
1.1
1.0
0.9
0.7
0.8
0.16


YNL069C
1.0
0.6
0.1
0.9
1.0
0.3
0.8
0.6
4.03


YNL135C
0.7
0.8
0.9
0.5
1.0
1.4
1.2
1.7
3.05


YOL039W
1.1
0.7
0.1
0.5
0.8
0.4
0.7
0.7
4.94


YOL120C
1.0
0.7
0.1
0.6
0.6
0.3
0.6
0.8
4.42


YOR230W
1.6
1.4
1.5
0.7
0.6
1.6
1.2
1.6
1.76


YOR298W
0.1
0.7
1.1
2.1
1.2
0.5
1.0
0.8
0.41


YPL048W
1.7
1.0
0.9
0.6
1.5
1.3
1.2
1.0
2.11


YPL179W
1.1
1.0
1.3
0.8
1.2
1.4
1.3
1.3
1.38


YPL218W
1.1
1.2
1.0
1.5
1.1
1.7
1.1
1.8
2.98


YPL220W
1.3
0.5
0.1
0.6
0.6
0.5
1.1
1.1
8.33


YPR080W
1.0
1.0
1.3
0.6
1.5
0.6
1.1
1.0
8.03


YPR181C
1.3
1.0
1.7
2.4
1.5
1.6
1.8
1.6
1.84


YBR290W
1.2
1.0
1.7
1.4
0.9
1.3
1.2
2.1
1.34


YCR091W
0.8
1.1
1.3
1.3
0.7
2.7
1.3
1.4
0.22


YFL026W
1.3
0.8
1.1
1.1
1.0
1.0
1.0
1.0
0.27


YOR003W
0.7
0.8
1.0
1.2
2.8
1.3
1.0
1.1
0.30


YCR038C
1.1
0.8
1.0
1.1
0.7
1.0
0.9
1.1
0.31


YDL119C
1.5
0.9
1.1
1.2
0.5
1.2
1.0
1.0
0.77


YDL220C
0.8
1.0
1.6
0.9
1.6
0.8
1.1
0.9
0.24


YDR125C
1.0
0.8
0.9
1.0
0.8
1.7
0.9
1.2
0.35


YDR225W
2.7
0.4
0.2
0.8
0.1
0.8
1.1
1.8
5.54


YER066W
1.5
0.7
0.9
1.1
0.5
3.3
1.1
1.1
0.66


YER076C
0.7
0.7
1.1
0.9
0.8
1.3
1.0
1.0
0.33


YFR006W
1.2
1.0
0.9
0.9
0.8
1.2
0.9
1.3
1.54


YGL208W
1.3
0.8
1.5
0.9
1.8
3.1
0.8
1.3
0.32


YGR023W
2.4
0.9
1.4
1.3
1.1
0.9
1.2
1.5
0.69


YGR108W
0.5
0.4
0.3
0.8
0.2
0.4
0.7
1.0
0.93


YHR195W
1.4
0.9
1.2
1.2
0.7
3.7
1.0
1.5
1.12


YIL050W
0.9
1.0
1.0
1.3
0.6
2.7
1.0
1.1
0.52


YJR050W
0.8
0.8
1.9
1.3
0.9
1.5
0.9
1.1
0.85


YKL093W
0.9
0.9
1.2
1.1
0.8
2.9
0.8
1.0
0.38


YMR053C
1.3
0.9
1.5
1.3
2.4
2.3
1.1
1.6
0.31


YNL139C
0.8
0.5
1.2
0.7
1.4
1.1
1.1
1.0
0.47


YOR122C
1.5
0.8
1.0
1.2
1.6
1.5
1.0
2.2
3.06


YOR312C
0.8
0.7
0.1
0.7
0.7
0.5
1.2
1.0
5.24


YOR327C
2.1
1.0
2.1
1.5
0.9
1.5
2.2
2.1
1.46


YPL001W
1.3
0.7
0.8
1.3
1.3
0.8
0.9
1.2
0.74


YPL230W
3.1
1.0
2.0
1.3
0.7
2.0
1.0
1.6
0.47


YER025W
1.2
0.7
0.6
2.1
0.8
2.6
1.8
2.3
1.96


YHR185C
0.7
0.8
0.4
1.7
1.3
3.2
1.4
3.0
1.64


YIL076W
1.1
0.8
0.8
1.4
1.0
0.8
1.2
2.5
3.73


YMR238W
1.2
1.0
1.5
1.2
2.3
1.4
2.2
2.4
1.36


YBR009C
0.8
0.5
0.4
1.1
0.2
0.4
1.0
2.4
7.00


YBR010W
1.0
0.7
0.4
1.0
0.3
0.8
1.1
2.3
7.25


YCL067C
1.6
1.0
1.4
2.1
2.2
1.7
0.8
2.2
3.15


YCR096C
1.4
1.0
1.0
2.1
2.1
1.8
1.0
2.1
2.34


YDL137W
1.5
1.6
1.7
1.4
1.3
2.3
1.3
2.2
4.95


YDL192W
1.3
1.1
0.9
1.2
1.3
1.3
1.1
2.3
5.57


YDR224C
1.1
0.7
0.5
1.7
0.3
1.1
1.2
2.2
5.62


YDR378C
0.8
0.9
0.8
1.4
0.8
1.0
1.7
2.2
2.40


YMR197C
1.0
1.1
1.5
4.1
1.7
1.9
1.2
2.2
1.20


YOL109W
1.0
0.8
0.5
1.4
1.0
0.8
1.6
2.2
4.13


YPL010W
1.3
1.1
1.1
1.3
1.2
1.3
1.3
2.0
3.25


YHR132C
1.1
0.8
1.2
0.9
1.4
2.3
0.8
1.3
1.52


YJL141C
1.2
0.8
1.4
0.8
0.8
2.2
1.4
1.6
0.94


YKR098C
1.9
1.1
1.4
1.4
0.9
3.9
1.1
1.6
0.55


YLR206W
1.3
0.8
1.4
0.8
2.4
2.3
1.1
1.2
0.72


YAL055W
1.3
1.2
1.5
1.6
1.1
2.6
1.3
1.3
0.62


YAR062W
−1.1
0.8
1.2
1.1
1.3
2.4
0.9
1.0
0.32


YBL102W
1.2
0.9
1.7
1.1
1.1
2.0
2.4
1.5
1.26


YBR161W
1.1
0.6
1.0
0.9
1.5
2.1
1.5
2.2
0.72


YCR039C
1.2
0.8
1.0
1.7
1.9
2.1
1.0
2.1
1.73


YDL018C
0.9
0.7
1.0
1.5
1.1
3.1
1.5
1.7
0.84


YDR022C
0.9
0.7
1.3
2.1
1.0
2.1
1.3
1.2
0.47


YDR181C
0.8
0.7
0.7
1.3
1.2
2.0
0.8
1.2
0.48


YGR036C
0.9
1.0
1.3
1.0
0.7
2.0
1.3
1.1
1.12


YGR120C
1.1
0.7
0.5
1.0
1.2
1.9
1.1
1.2
0.36


YGR131W
1.1
0.5
1.4
2.0
0.8
2.6
1.3
1.0
0.41


YGR167W
1.1
1.1
1.6
1.7
1.6
2.8
1.3
1.7
1.79


YHL024W
1.1
1.6
1.6
2.1
2.9
3.8
1.4
1.4
0.58


YJL113W
1.2
0.7
0.9
1.3
1.7
2.1
0.9
1.5
0.41


YJL146W
−1.1
1.1
0.8
1.5
1.2
1.8
1.0
1.3
0.30


YJR019C
2.4
1.1
1.4
0.8
1.1
2.6
1.8
1.4
0.33


YJR049C
1.6
1.0
2.1
1.2
1.2
1.7
0.9
1.2
0.44


YLR078C
2.9
1.0
0.8
1.2
0.6
2.2
1.2
1.2
1.02


YNR037C
1.5
0.7
2.0
1.2
0.8
1.9
1.4
1.6
1.34


YOR028C
1.5
0.6
0.8
1.3
1.1
3.7
0.8
1.7
0.78










[0041] The tables show that the expressed mRNA of about 700 of 2400 unknown yeast genes was induced by any one of toxic chemical substances such as heavy metals, agricultural chemicals, surfactants (Table 1), as well as the expressed mRNA of 167 mitochondria-located genes (Table 2), 52 DNA repair genes (Table 3), 161 energy genes (Table 4), 142 transport facilitation genes (Table 5), 90 stress protein genes (Table 6), 142 metabolism genes (Table 7), 60 detoxification genes (Table 8), and 507 genes belonging to other category (Table 9). Here, when the value of the following is 2 or more, then it is considered significant:
2ThelevelofexpressedmRNAinthepresenceofchemicalsubstanceThelevelofexpressedmRNAintheabsenceofchemicalsubstance.


[0042] “Intensity” indicated in the rightmost column of Tables 1 to 9 is a value of the level of expressed mRNA of each gene in control cells as divided by the average level of the expressions of the whole genes. When the intensity is low, the error of measurement may be possibly large. The detection is considered more precise when expression magnification (expressed mRNA in the presence of chemical substance/expressed mRNA in the absence of chemical substance) is larger. Yeast gene as used in the processes according to the invention is selected, of which the intensity is preferably 0.3 or more, more preferably 0.5 or more, and of which the expression magnification is preferably 3 or more, more preferably 5 or more.


Claims
  • 1. A process for detecting a toxic substance, which comprises detecting mRNA that is expressed in the presence of a test material by a cell comprising a yeast gene that is selected from a group consisting of the following, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof: YBR072W, YCR102C, YCR107W, YDL218W, YDL243C, YDR453C, YDR533C, YFL014W, YFL056C, YFL057C, YGR110W, YJR155W, YKL071W, YKR076W, YLL060C, YLR460C, YMR090W, YNL331C, YNL332W, YNL335W, YOL150C, YOL165C, YPL171C, YPR167C, YBL048W, YBL064C, YBL107C, YBR008C, YBR173C, YBR256C, YBR296C, YDL021W, YFL022C, YFL024C, YFL061W, YGL121C, YGL158W, YGR043C, YHR029C, YHR112C, YHR139C, YHR179W, YHR209W, YIR030C, YJR010W, YJR048W, YKL001C, YKL107W, YKR075C, YKR097W, YLL056C, YLR297W, YLR303W, YML087C, YMR096W, YNL274C, YOL151W, YOR226C, YOR338W, YOR391C, YPL280W, YDR406W, YJL153C, YLR346C, YOR049C, YOR153W, YPL088W, YAL034C, YDL124W, YDL174C, YDR476C, YGL156W, YGR035C, YGR157W, YGR213C, YGR281W, YGR284C, YHL047C, YHR043C, YHR044C, YHR054C, YJR073C, YKL165C, YLR008C, YMR315W, YNL211C, YOL031C, YOL101C, YOR303W, YAL005C, YAR031W, YBL005W-A, YBL022C, YBL041W, YBL049W, YBL075C, YBL078C, YBR062C, YBR169C, YBR294W, YCL020W, YCL035C, YCL043C, YCL050C, YCL057W, YCR012W, YCR013C, YCR060W, YDL007W, YDL027C, YDL097C, YDL110C, YDL126C, YDL169C, YDR070C, YDR155C, YDR158W, YDR204W, YDR210W, YDR214W, YDR258C, YDR313C, YDR368W, YDR435C, YER012W, YER037W, YER091C, YER103W, YFL044C, YFR003C, YFR010W, YFR020W, YFR024C, YFR044C, YFR053C, YGL006W, YGL048C, YGL062W, YGL141W, YGL157W, YGL163C, YGL180W, YGL184C, YGR010W, YGR028W, YGR032W, YGR048W, YGR124W, YGR135W, YGR142W, YGR161C, YGR192C, YGR197C, YGR201C, YGR212W, YGR231C, YGR244C, YGR254W, YGR268C, YHL030W, YHR016C, YHR018C, YHR055C, YHR087W, YHR166C, YIL160C, YIR017C, YJL034W, YJL048C, YJL052W, YJL144W, YJL163C, YJR009C, YJR069C, YJR074W, YJR130C, YJR149W, YKL065C, YKL073W, YKL103C, YKL142W, YKL210W, YKL218C, YKR011C, YKR018C, YKR046C, YKR049C, YLL024C, YLL026W, YLR027C, YLR080W, YLR107W, YLR121C, YLR132C, YLR133W, YLR155C, YLR158C, YLR161W, YLR195C, YLR217W, YLR328W, YLR336C, YLR345W, YLR370C, YLR423C, YML004C, YML092C, YML128C, YML130C, YML131W, YMR040W, YMR118C, YMR214W, YMR251W, YMR297W, YMR322C, YNL036W, YNL055C, YNL071W, YNL094W, YNL134C, YNL155W, YNL160W, YNL239W, YNL241C, YOL005C, YOR020C, YOR027W, YOR037W, YOR059C, YOR120W, YOR134W, YOR152C, YOR173W, YOR289W, YOR362C, YPL240C, YPR030W, YAL008W, YAL023C, YAL060W, YAL062W, YAR009C, YBL101C, YBR006W, YBR046C, YBR052C, YBR053C, YBR056W, YBR099C, YBR137W, YBR139W, YBR149W, YBR170C, YBR177C, YBR203W, YBR207W, YBR212W, YBR239C, YBR284W, YBR293W, YCL018W, YCL033C, YCL040W, YCL049C, YCR062W, YCR067C, YCR082W, YDL010W, YDL020C, YDL024C, YDL054C, YDL095W, YDL100C, YDL115C, YDL144C, YDL198C, YDL223C, YDL245C, YDL246C, YDR001C, YDR032C, YDR058C, YDR072C, YDR127W, YDR168W, YDR169C, YDR188W, YDR231C, YDR261C, YDR264C, YDR272W, YDR293C, YDR304C, YDR330W, YDR403W, YDR411C, YDR427W, YDR436W, YDR497C, YDR511W, YDR516C, YDR519W, YDR545W, YEL012W, YEL030W, YER004W, YER009W, YER021W, YER035W, YER053C, YER079W, YER094C, YER096W, YER125W, YER158C, YER163C, YER175C, YER177W, YER178W, YER185W, YFL006W, YFL010C, YFL016C, YFL029C, YFL030W, YFL031W, YFL032W, YFL038C, YFL041W, YFR004W, YFR047C, YFR050C, YFR052W, YGL011C, YGL013C, YGL037C, YGL047W, YGL053W, YGL091C, YGL094C, YGL127C, YGL150C, YGL199C, YGL207W, YGL248W, YGR008C, YGR037C, YGR055W, YGR101W, YGR130C, YGR154C, YGR194C, YGR221C, YGR232W, YGR248W, YGR253C, YGR256W, YHL008C, YHR027C, YHR053C, YHR057C, YHR111W, YHR138C, YHR161C, YHR164C, YHR169W, YHR174W, YHR176W, YHR199C, YIL010W, YIL034C, YIL041W, YIL045W, YIL087C, YIL107C, YIL142W, YIL155C, YIR034C, YIR036C, YIR037W, YIR038C, YIR039C, YJL001W, YJL031C, YJL035C, YJL053W, YJL057C, YJL066C, YJL068C, YJL082W, YJL099W, YJL102W, YJL151C, YJL152W, YJL161W, YJL164C, YJL171C, YJL172W, YJL210W, YJL219W, YJR008W, YJR045C, YJR046W, YJR106W, YJR117W, YJR137C, YKL007W, YKL026C, YKL035W, YKL091C, YKL104C, YKL117W, YKL145W, YKL146W, YKL151C, YKL152C, YKL153W, YKL193C, YKL195W, YKL213C, YKL215C, YLL028W, YLL039C, YLL058W, YLR054C, YLR103C, YLR120C, YLR136C, YLR149C, YLR152C, YLR178C, YLR259C, YLR299W, YLR324W, YLR327C, YLR348C, YLR350W, YLR356W, YLR362W, YLR387C, YLR429W, YML054C, YML070W, YML100W, YML117W, YML125C, YMR004W, YMR008C, YMR009W, YMR020W, YMR067C, YMR089C, YMR097C, YMR102C, YMR105C, YMR107W, YMR152W, YMR180C, YMR184W, YMR191W, YMR219W, YMR271C, YMR275C, YMR295C, YMR314W, YMR316W, YNL006W, YNL007C, YNL012W, YNL044W, YNL045W, YNL074C, YNL092W, YNL093W, YNL104C, YNL115C, YNL156C, YNL231C, YNL234W, YNL237W, YNL281W, YNL305C, YNL333W, YNR010W, YNR019W, YNR033W, YNR059W, YNR068C, YNR069C, YOL032W, YOL036W, YOL047C, YOL071W, YOL082W, YOL083W, YOL117W, YOL119C, YOL126C, YOL131W, YOL153C, YOL162W, YOL163W, YOL164W, YOR019W, YOR035C, YOR036W, YOR099W, YOR117W, YOR124C, YOR130C, YOR132W, YOR157C, YOR185C, YOR197W, YOR259C, YOR261C, YOR273C, YOR288C, YOR332W, YOR336W, YOR347C, YPL017C, YPL087W, YPL106C, YPL109C, YPL149W, YPL154C, YPL196W, YPL206C, YPL222W, YPR023C, YPR024W, YPR026W, YPR067W, YPR103W, YPR108W, YPR151C, YAL012W, YBR029C, YBR222C, YCL009C, YCL027W, YCL064C, YCR098C, YDL222C, YDR055W, YDR077W, YDR502C, YEL001C, YEL042W, YER026C, YER106W, YGR136W, YGR138C, YHR137W, YHR142W, YIL023C, YIL153W, YJL073W, YJR004C, YJR054W, YKL039W, YKL086W, YKL163W, YKR091W, YLR109W, YLR194C, YLR250W, YMR095C, YMR189W, YNL106C, YNL169C, YNL322C, YOR181W, YOR198C, YOR208W, YOR247W, YPL089C, YAL038W, YAL053W, YBR023C, YBR214W, YBR295W, YCR048W, YDL072C, YDL204W, YDR085C, YDR098C, YDR259C, YDR380W, YDR388W, YDR391C, YDR432W, YDR481C, YDR510W, YER069W, YGL022W, YGL126W, YGL209W, YGL255W, YGR189C, YGR282C, YHL035C, YHR030C, YIL022W, YIL024C, YIL117C, YIL123W, YIL140W, YIL154C, YJL088W, YJL108C, YJL149W, YJL159W, YJL186W, YJR148W, YKL096W, YLR180W, YLR273C, YLR300W, YLR307W, YLR378C, YLR391W, YMR094W, YMR104C, YMR276W, YMR296C, YNL190W, YNL208W, YNL300W, YNR064C, YOL013C, YOL058W, YOR248W, YOR355W, YPL052W, YPL163C, YPR079W, YAR028W, YBR146W, YBR183W, YCL038C, YCR071C, YDL008W, YDR019C, YDR031W, YDR115W, YDR486C, YER038C, YER130C, YFL054C, YGL136C, YGR146C, YGR207C, YHL040C, YIL167W, YJL020C, YKR039W, YLR031W, YLR205C, YMR072W, YMR140W, YMR173W, YMR195W, YMR226C, YNL037C, YNR002C, YOL143C, YOR136W, YOR215C, YOR382W, YOR383C, YPL054W, YPL271W, YPR127W, YAL044C, YAL054C, YAR010C, YAR027W, YAR071W, YBL001C, YBL043W, YBL057C, YBR014C, YBR024W, YBR035C, YBR068C, YBR111C, YBR116C, YBR147W, YBR168W, YBR246W, YBR273C, YCR004C, YCR021C, YCR037C, YCR088W, YDL022W, YDL128W, YDL238C, YDR003W, YDR009W, YDR033W, YDR084C, YDR104C, YDR270W, YDR315C, YDR340W, YDR357C, YDR358W, YDR396W, YDR405W, YDR410C, YDR434W, YDR482C, YDR487C, YDR520C, YDR534C, YDR539W, YEL011W, YEL065W, YEL066W, YER039C, YER044C, YER067W, YER080W, YER107C, YFL020C, YFL028C, YFL043C, YFR015C, YGL001C, YGL008C, YGL068W, YGL073W, YGL104C, YGL113W, YGL154C, YGL167C, YGL229C, YGL242C, YGL249W, YGL253W, YGR052W, YGR060W, YGR065C, YGR106C, YGR111W, YGR220C, YGR257C, YHL023C, YHL048W, YHR004C, YHR037W, YHR071W, YHR092C, YHR190W, YIL007C, YIL033C, YIL070C, YIL088C, YIL111W, YIR002C, YIR016W, YIR035C, YIR043C, YJL012C, YJL083W, YJL089W, YJL116C, YJL131C, YJL132W, YJL196C, YJR061W, YJR086W, YJR142W, YJR161C, YKL008C, YKL013C, YKL041W, YKL067W, YKL138C, YKL139W, YKL150W, YKL175W, YKR006C, YKR014C, YKR070W, YLL023C, YLR023C, YLR093C, YLR118C, YLR142W, YLR225C, YLR241W, YLR251W, YLR252W, YLR270W, YML030W, YML110C, YMR021C, YMR027W, YMR148W, YMR181C, YMR262W, YMR272C, YMR298W, YNL011C, YNL130C, YNL214W, YNL259C, YOL129W, YOR042W, YOR052C, YOR137C, YOR149C, YOR165W, YOR270C, YOR285W, YOR367W, YPL018W, YPL156C, YPL186C, YPL203W, YPL216W, YPL255W, YPR006C, YPR073C, YPR098C, YBR050C, YBR145W, YBR299W, YDR518W, YEL020C, YFL062W, YGL039W, YGL134W, YJL217W, YJR159W, YLR126C, YNL249C, YNL284C, YNL336W, YOL157C, YOR344C, YOR381W, YPL265W, YPR124W, YBR074W, YBR109C, YBR126C, YBR201W, YCR005C, YDL248W, YDR041W, YDR105C, YDR268W, YDR452W, YEL075C, YER046W, YER050C, YER136W, YER159C, YGL250W, YGR019W, YGR042W, YGR053C, YGR066C, YGR247W, YGR255C, YGR295C, YHL044W, YHR145C, YIL058W, YIL065C, YIL083C, YIL098C, YIL172C, YJL030W, YJL185C, YJL213W, YJR029W, YJR099W, YJR122W, YJR125C, YKL190W, YKR020W, YLL025W, YLL051C, YLR043C, YLR090W, YLR100W, YLR108C, YLR290C, YML068W, YMR051C, YMR139W, YMR178W, YMR193W, YNL015W, YNL079C, YNL122C, YNL223W, YNL285W, YNL293W, YNR007C, YNR035C, YNR061C, YOL016C, YOL104C, YOR220W, YOR221C, YOR374W, YPL123C, YPR077C, YPR107C, YPR147C, YBR093C, YBR196C, YEL041W, YEL047C, YER023W, YER119C, YFL055W, YGR209C, YIL124W, YKL187C, YLL055W, YMR318C, YOL152W, YAL007C, YBR067C, YBR115C, YBR285W, YBR292C, YDL043C, YDL123W, YDL131W, YDL168W, YDL212W, YDR056C, YDR132C, YDR154C, YDR183W, YDR216W, YDR253C, YDR295C, YDR494W, YDR513W, YEL072W, YER045C, YER061C, YER181C, YFL052W, YFL058W, YFR030W, YGL089C, YGL096W, YGL114W, YGL193C, YGL202W, YGL204C, YGL259W, YGR006W, YGR070W, YGR088W, YHL034C, YHL036W, YHR048W, YHR104W, YHR163W, YIL060W, YIL136W, YIR024C, YJL036W, YJL045W, YJL060W, YJL101C, YJL155C, YJR085C, YJR109C, YJR156C, YKL070W, YKL161C, YKL221W, YKR071C, YLL009C, YLL050C, YLR092W, YLR145W, YLR156W, YLR163C, YLR220W, YLR280C, YLR311C, YLR390W, YML116W, YMR034C, YMR038C, YMR081C, YMR250W, YNL240C, YNL260C, YNL277W, YNR074C, YOL044W, YOL084W, YOL147C, YOL159C, YOR184W, YOR228C, YOR255W, YPL223C, YPR160W, YDL182W, YBR047W, YBR054W, YBR291C, YDR069C, YER124C, YER131W, YGR044C, YIL094C, YKR007W, YMR240C, YNR050C, YOR007C, YAL015C, YBL065W, YBR105C, YBR182C, YBR186W, YBR244W, YBR272C, YCL069W, YDL025C, YDL059C, YDL085W, YDL113C, YDL244W, YDR018C, YDR054C, YDR202C, YDR223W, YDR350C, YDR353W, YDR374C, YDR512C, YEL052W, YEL070W, YER098W, YFR017C, YGL046W, YGL067W, YGL098W, YGL117W, YGL146C, YGL240W, YGR011W, YGR067C, YGR133W, YGR153W, YGR223C, YHR116W, YHR124W, YIL097W, YIL168W, YJL103C, YJL221C, YJR036C, YJR095W, YKL085W, YKL133C, YKL162C, YKL188C, YKL217W, YKR061W, YKR105C, YLL062C, YLR174W, YLR216C, YLR247C, YLR260W, YLR267W, YLR389C, YML007W, YMR041C, YMR177W, YMR253C, YNL009W, YNL117W, YNL128W, YNL183C, YNR073C, YOL133W, YOL158C, YOR133W, YOR225W, YOR227W, YPL161C, YPL166W, YPL202C, YPL224C, YPR015C, YPR086W, YPR201W, YAL061W, YAL067C, YAR007C, YBL033C, YBL056W, YBL086C, YBR026C, YBR073W, YBR101C, YBR117C, YBR123C, YBR213W, YBR269C, YBR280C, YCR036W, YDL132W, YDL149W, YDL200C, YDL234C, YDL242W, YDR099W, YDR177W, YDR256C, YDR392W, YDR394W, YDR531W, YEL071W, YER014W, YER042W, YER090W, YER184C, YFL059W, YFR042W, YFR046C, YFR049W, YGL026C, YGL058W, YGL185C, YGL227W, YGL252C, YGL254W, YGR089W, YGR112W, YGR134W, YGR276C, YHL019C, YHR012W, YHR017W, YHR028C, YHR106W, YHR109W, YHR156C, YIL036W, YIL046W, YIL143C, YIL152W, YIL159W, YIL164C, YJL071W, YJL094C, YJL154C, YJR056C, YJR072C, YJR110W, YJR139C, YKL025C, YKL034W, YKL064W, YKL171W, YKL196C, YKR012C, YKR068C, YKR069W, YLL001W, YLL057C, YLL061W, YLR064W, YLR070C, YLR099C, YLR144C, YLR157C, YLR160C, YLR164W, YLR364W, YLR421C, YML032C, YML042W, YML112W, YML118W, YMR114C, YMR115W, YMR258C, YNL181W, YNL191W, YNL212W, YNL213C, YNL250W, YNL265C, YNL312W, YNR032W, YOL038W, YOL049W, YOL064C, YOR088W, YOR155C, YOR257W, YOR265W, YOR377W, YOR386W, YPL031C, YPL113C, YPL124W, YPL151C, YPL249C, YPL260W, YPL274W, YPR048W, YPR061C, YPR093C, YPR125W, YPR158W, YPR168W, YPR169W, YPR174C, YPR180W, YPR193C, YPR200C, YAL014C, YAL017W, YAL049C, YBL019W, YBL058W, YBR001C, YBR013C, YBR018C, YBR037C, YBR045C, YBR051W, YBR063C, YBR128C, YBR129C, YBR204C, YBR241C, YBR255W, YBR281C, YCL044C, YCL055W, YCR014C, YCR019W, YCR024C, YCR105W, YDL065C, YDL089W, YDL143W, YDL173W, YDL193W, YDL197C, YDL206W, YDL230W, YDL233W, YDR040C, YDR071C, YDR078C, YDR109C, YDR140W, YDR194C, YDR212W, YDR221W, YDR257C, YDR271C, YDR287W, YDR294C, YDR316W, YDR329C, YDR338C, YDR369C, YDR421W, YDR425W, YDR485C, YDR488C, YDR504C, YDR505C, YDR506C, YDR515W, YEL005C, YEL037C, YEL044W, YER017C, YER048C, YER052C, YER078C, YER089C, YER092W, YER100W, YER162C, YER182W, YFL021W, YFL042C, YFR045W, YFR051C, YFR056C, YGL040C, YGL041C, YGL045W, YGL057C, YGL093W, YGL105W, YGL125W, YGL166W, YGL181W, YGL183C, YGL215W, YGL216W, YGL221C, YGL223C, YGR007W, YGR029W, YGR155W, YGR156W, YGR186W, YGR198W, YGR210C, YGR211W, YGR237C, YGR250C, YGR258C, YGR266W, YGR270W, YGR274C, YGR277C, YHL021C, YHL037C, YHL038C, YHR082C, YHR083W, YHR134W, YHR160C, YHR171W, YHR180W, YHR205W, YIL062C, YIL072W, YIL075C, YIL099W, YIL108W, YIL165C, YIL170W, YIR009W, YIR018W, YIR031C, YIR032C, YJL032W, YJL049W, YJL128C, YJL165C, YJR044C, YJR052W, YJR090C, YJR091C, YJR103W, YJR104C, YJR153W, YKL059C, YKL079W, YKL090W, YKL094W, YKL192C, YKL209C, YKR052C, YKR102W, YKR106W, YLL054C, YLR025W, YLR097C, YLR200W, YLR226W, YLR248W, YLR266C, YLR392C, YLR427W, YML013W, YML029W, YML041C, YML051W, YML078W, YML079W, YML088W, YML099C, YMR056C, YMR068W, YMR091C, YMR110C, YMR160W, YMR186W, YMR255W, YNL005C, YNL026W, YNL039W, YNL063W, YNL064C, YNL077W, YNL083W, YNL147W, YNL176C, YNL194C, YNL253W, YNL257C, YNL261W, YNL264C, YNL276C, YNR006W, YNR034W, YNR047W, YNR051C, YNR071C, YOL065C, YOL067C, YOR005C, YOR008C, YOR022C, YOR023C, YOR058C, YOR069W, YOR087W, YOR138C, YOR229W, YOR256C, YOR267C, YPL005W, YPL020C, YPL022W, YPL105C, YPL147W, YPL150W, YPL152W, YPL164C, YPL168W, YPL180W, YPL188W, YPL194W, YPR025C, YPR047W, YPR049C, YPR066W, YPR081C, YPR134W, YPR140W, YPR148C, YPR155C, YPR172W, YPR185W, YAL018C, YAR064W, YBR012C, YBR076W, YBR287W, YDR043C, YDR250C, YDR373W, YFR014C, YGL191W, YGR180C, YHR136C, YJL026W, YJL037W, YLR038C, YNL058C, YOR031W, YGR087C, YIL166C, YHR008C, YIL129C, YGL256W, YJR030C, YMR077C, YBR264C, YPL177C, YKR040C, YGL056C, YDR128W, YGR139W, YBL101W-A, YOR253W, YOL026C, YDR278C, YHR095W, YCL042W, YNL200C, YPL221W, YLR415C, YMR058W, YPR037C, YER072W, YML028W, YOR325W, YAL039C, YMR112C, YJR107W, YGL088W, YJR058C, YNL142W, YDR090C, YMR071C, YBL093C, YGR293C, YML055W, YDL017W, YDL210W, YGL055W, YCL025C, YDR080W, YDL181W, YNR030W, YJL017W, YIL127C, YDR281C, YDR366C, YFR026C, YJL212C, YPL215W, YEL019C, YBR132C, YHL018W, YNL196C, YPL038W, YAR047C, YPL262W, YHL006C, YPL225W, YBR124W, YOR148C, YKR053C, YBL044W, YER029C, YLR360W, YCL056C, YCR007C, YGR239C, YNL256W, YPR146C, YLR377C, YKL097C, YBR066C, YLR338W, YDL229W, YBR253W, YJR027W, YKL198C, YBL030C, YBR031W, YBR118W, YBR162C, YBR221C, YCR024C-A, YCR106W, YDL046W, YDR012W, YDR133C, YDR134C, YDR276C, YDR342C, YDR343C, YEL027W, YEL034W, YGR038W, YGR243W, YGR279C, YHR094C, YHR105W, YHR175W, YHR181W, YIL056W, YIL162W, YJL059W, YJL097W, YJL158C, YJR105W, YKL051W, YKL056C, YKL097W-A, YKL100C, YKL141W, YKR066C, YLR134W, YLR258W, YLR339C, YML058W, YMR083W, YMR203W, YNL209W, YNL307C, YOL030W, YOR178C, YPL028W, YPR028W, YPR113W, YPR149W, YPR150W, YPR183W, YAL016W, YBL099W, YBL100C, YBR011C, YBR096W, YBR100W, YBR127C, YBR283C, YBR286W, YCL008C, YCL058C, YCR030C, YCR034W, YCR069W, YDL015C, YDL023C, YDL061C, YDL086W, YDR038C, YDR039C, YDR050C, YDR151C, YDR178W, YDR233C, YDR284C, YDR298C, YDR345C, YDR359C, YDR382W, YDR385W, YDR400W, YDR407C, YDR538W, YEL024W, YEL033W, YEL063C, YER057C, YER081W, YER120W, YFL011W, YGL012W, YGL206C, YGR022C, YGR026W, YGR082W, YGR107W, YGR172C, YGR191W, YGR204W, YGR260W, YHL005C, YHL046C, YHR025W, YHR026W, YHR123W, YHR126C, YHR143W, YIL011W, YIL015W, YIL018W, YIL157C, YIR041W, YJL016W, YJL121C, YJL133W, YJL138C, YJL191W, YJR018W, YJR047C, YJR077C, YJR119C, YJR121W, YJR123W, YJR143C, YJR145C, YKL060C, YKL147C, YKL148C, YKL157W, YKL164C, YKL169C, YKR033C, YLL041C, YLL064C, YLR041W, YLR044C, YLR056W, YLR058C, YLR081W, YLR089C, YLR110C, YLR177W, YLR264W, YLR284C, YLR304C, YLR340W, YLR354C, YLR372W, YLR388W, YML022W, YMR007W, YMR011W, YMR015C, YMR092C, YMR101C, YMR156C, YMR205C, YMR215W, YMR261C, YMR323W, YNL069C, YNL135C, YNL195C, YNR076W, YOL039W, YOL073C, YOL086C, YOL120C, YOL156W, YOL161C, YOR002W, YOR009W, YOR010C, YOR085W, YOR108W, YOR128C, YOR129C, YOR142W, YOR161C, YOR176W, YOR230W, YOR298W, YPL004C, YPL036W, YPL048W, YPL057C, YPL059W, YPL061W, YPL135W, YPL179W, YPL218W, YPL220W, YPL246C, YPL272C, YPR063C, YPR080W, YPR181C, YBR290W, YCR010C, YCR091W, YDL107W, YDL129W, YDR066C, YDR529C, YFL026W, YGL018C, YGL059W, YNL144C, YOR003W, YAL037W, YAR023C, YBR003W, YBR020W, YBR044C, YBR091C, YBR185C, YBR282W, YCR015C, YCR038C, YCR043C, YDL119C, YDL146W, YDL220C, YDR057W, YDR123C, YDR125C, YDR222W, YDR225W, YDR277C, YDR286C, YDR347W, YDR408C, YDR438W, YDR479C, YDR483W, YEL039C, YEL057C, YEL073C, YER066W, YER076C, YER084W, YER121W, YER189W, YFL017C, YFL046W, YFR006W, YFR008W, YGL115W, YGL208W, YGL214W, YGL218W, YGR021W, YGR023W, YGR024C, YGR064W, YGR076C, YGR096W, YGR108W, YGR174C, YGR182C, YGR236C, YGR288W, YHL042W, YHR195W, YHR210C, YIL006W, YIL012W, YIL028W, YIL050W, YIL057C, YIL089W, YIL102C, YIL113W, YIL122W, YJL100W, YJL169W, YJL199C, YJR039W, YJR050W, YJR101W, YKL003C, YKL016C, YKL061W, YKL093W, YKL121W, YKL160W, YKL170W, YKL194C, YKR034W, YKR067W, YLR006C, YLR016C, YLR030W, YLR036C, YLR112W, YLR125W, YLR128W, YLR204W, YLR211C, YLR233C, YLR257W, YLR288C, YLR326W, YLR334C, YLR395C, YLR408C, YLR414C, YLR444C, YML050W, YML107C, YML120C, YMR031C, YMR053C, YMR073C, YMR162C, YMR204C, YMR206W, YMR284W, YNL010W, YNL025C, YNL127W, YNL139C, YNL217W, YOL116W, YOL118C, YOR053W, YOR100C, YOR103C, YOR122C, YOR150W, YOR187W, YOR251C, YOR312C, YOR327C, YOR348C, YOR352W, YOR388C, YOR394W, YPL001W, YPL033C, YPL066W, YPL148C, YPL230W, YPL275W, YPL276W, YPR005C, YPR014C, YPR192W, YPR194C, YBR005W, YER025W, YFL027C, YGL080W, YGL205W, YHL028W, YHR185C, YIL076W, YJL166W, YLR046C, YMR035W, YMR238W, YMR252C, YNL192W, YNL202W, YOL108C, YOR385W, YPR165W, YAR033W, YBL038W, YBR009C, YBR010W, YBR151W, YCL067C, YCR096C, YDL137W, YDL192W, YDR073W, YDR086C, YDR224C, YDR377W, YDR378C, YER015W, YGL187C, YHR162W, YJL167W, YJL216C, YKR009C, YLR165C, YMR197C, YNL157W, YOL002C, YOL109W, YOR180C, YPL010W, YPL233W, YBR036C, YDR297W, YGR149W, YGR224W, YNL043C, YPL067C, YPL170W, YCR046C, YDR387C, YFL050C, YGL051W, YHR132C, YIL112W, YJL141C, YKR098C, YLR052W, YLR206W, YML129C, YNL203C, YNR014W, YOL043C, YOL096C, YPR184W, YAL028W, YAL055W, YAR062W, YBL095W, YBL102W, YBR122C, YBR157C, YBR161W, YBR251W, YBR298C, YCR039C, YCR083W, YDL018C, YDL067C, YDL078C, YDL091C, YDL215C, YDL216C, YDR022C, YDR067C, YDR079W, YDR181C, YDR186C, YDR196C, YDR262W, YDR306C, YDR319C, YER188W, YGL004C, YGL035C, YGR036C, YGR062C, YGR120C, YGR131W, YGR141W, YGR167W, YGR287C, YHL024W, YHR080C, YHR097C, YIL077C, YJL046W, YJL070C, YJL096W, YJL113W, YJL146W, YJL180C, YJR019C, YJR049C, YKR058W, YLL005C, YLR078C, YLR151C, YLR271W, YLR295C, YLR351C, YLR375W, YMR023C, YMR025W, YMR135C, YMR210W, YMR267W, YMR278W, YMR293C, YNL073W, YNR037C, YNR040W, YNR072W, YOR028C, YOR316C, YOR328W, YOR363C, YPL039W, YPL040C, YPL099C, YPL107W, YPL134C, YPL138C, and YPL140C.
  • 2. The process according to claim 1, wherein the yeast gene belongs to a category of unknown yeast genes.
  • 3. The process according to claim 1, wherein the yeast gene belongs to a category of mitochondria genes.
  • 4. The process according to claim 1, wherein the yeast gene belongs to a category of DNA repair genes.
  • 5. The process according to claim 1, wherein the yeast gene belongs to a category of energy genes.
  • 6. The process according to claim 1, wherein the yeast gene belongs to a category of transport facilitation genes.
  • 7. The process according to claim 1, wherein the yeast gene belongs to a category of stress protein genes.
  • 8. The process according to claim 1, wherein the yeast gene belongs to a category of metabolism genes.
  • 9. The process according to claim 1, wherein the yeast gene belongs to a category of detoxification genes.
  • 10. The process according to any one of claims 1 to 9, wherein the toxic substance is mutagenic.
  • 11. The process according to any one of claims 1 to 10, wherein the mRNA is amplified by reverse transcription-PCR, and then detected.
  • 12. The process according to claim 11, which comprises: (1) adding a test material to the cell, and incubating the mixture; (2) extracting mRNA from the cell; (3) preparing cDNA from the mRNA via reverse transcription using labeled nucleotides; and (4) hybridizing the cDNA as used as probe with the gene as defined in claim 1.
  • 13. The process according to claim 12, wherein step (4) as defined in claim 12 is conducted on a microarray containing the gene as defined in claim 1.
  • 14. The process according to any one of claims 1 to 10, wherein the mRNA is detected by northern blotting.
  • 15. The process according to claim 14, which comprises: (1) adding a test material to the cell, and incubating the mixture; (2) extracting mRNA from the cell; and (3) hybridizing the mRNA with the gene as defined in claim 1.
  • 16. The process according to claim 15, wherein step (3) as defined in claim 15 is conducted on a microarray containing the gene as defined in claim 1.
  • 17. The process according to any one of claims 1 to 10, wherein the detection of mRNA is conducted by detecting the production of a polypeptide encoded by the gene as defined in claim 1.
Priority Claims (1)
Number Date Country Kind
2001-255380 Aug 2001 JP
PCT Information
Filing Document Filing Date Country Kind
PCT/JP02/08494 8/23/2002 WO