Claims
- 1. A method for encapsulating biological substances in biocompatible microcapsules comprising:
- (a) maintaining a coating-forming liquid film sheet transverse to a vertical plane, said sheet comprising an organic polymerizable monomer liquid,
- (b) causing droplets comprising biological substances in an aqueous medium to fall downwardly through said liquid film sheet to form microcapsules comprising cores of said droplets coated by said film,
- (c) permitting said microcapsules to fall downwardly from said liquid fill sheet, and
- (d) polymerizing said liquid film coatings during descent of said microcapsules below said sheet to form a permeable polymer coating of a sufficient structural integrity so that said microcapsules are self-supporting.
- 2. The method of claim 1 in which said biological substances comprise cells capable of secreting a selected biologically active product or of providing a selected biological function to an individual.
- 3. The method of claim 1 in which said monomer comprises a modified polyetheylene glycol.
- 4. The method of claim 1 in which polymerization of step (d) is performed by photopolymerization.
Parent Case Info
This is a division of application Ser. No. 08/113,778 filed 27 Aug., 1993, U.S. Pat. No. 5,453,368.
US Referenced Citations (14)
Divisions (1)
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Number |
Date |
Country |
Parent |
113778 |
Aug 1993 |
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