Claims
- 1. A method of increasing the content of lean meat in edible animals which comprises administering to an edible animal an effective amount of a compound of the formula ##STR38## wherein R.sub.1 and R.sub.4 may be one or more groups which may be the same or different and are selected from the group consisting of hydrogen, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, hydroxy, halogen, trifluoromethyl, carboxy, hydroxyalkyl, alkoxycarbonyl, C.sub.1 to C.sub.4 thioalkyl, sulfonyl and sulfinyl; X is a divalent radical consisting of ##STR39## wherein R' is selected from the group consisting of hydrogen, C.sub.1 to C.sub.4 alkyl and C.sub.1 to C.sub.4 acyl; R.sub.2 and R.sub.3 may be the same or differenct and are selected from the group consisting of hydrogen and C.sub.1 C.sub.4 alkyl; R.sub.5 and R.sub.6 are selected from the group consisting of hydrogen, carboxy, alkoxycarbonyl, hydroxymethyl, --CH.sub.2 OCH.sub.2 COOR.sub.7 and --CH.sub.2 OCH.sub.2 CH.sub.2 OR.sub.7 where R.sub.7 is hydrogen or C.sub.1 to C.sub.4 alkyl; except that R.sub.5 and R.sub.6 may not both be hydrogen; the asterisks denote asymmetric carbon atoms; or a pharmaceutically acceptable salt or ester thereof, the enantiomers thereof, the racemic mixtures thereof and the diastereomeric mixtures thereof.
- 2. A method according to claim 1 wherein R.sub.1 of the compound is one or two of the groups as defined.
- 3. A method according to claim 2 wherein the compound is 1,3-Benzodioxole-2,2-dicarboxylic acid, 5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-, disodium salt (R*,R*)-(+/-).
- 4. A method according to claim 2 wherein the compound is 1,3-Benzodioxole-2,2=dicarboxylic acid, 5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-, dimethyl ester, hydrobromide,(R*,R*)-(+/-).
- 5. A method according to claim 2 wherein the compound is 1,3-Benzodioxole-2,2-dicarboxylic acid, 5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-, disodium salt,[R-(R*,R*)].
- 6. A method according to claim 2 wherein the compound if 1,3-Benzodioxole-2,2-dicarboxylic acid, 5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-, bis(1-methylethyl) ester, hydrochloride, [R-(R*,R*)].
Parent Case Info
This is Continuation-in-Part Application of copending U.S. Pat. application Ser. No. 07/519,192 filed May 4, 1990.
US Referenced Citations (21)
Foreign Referenced Citations (1)
Number |
Date |
Country |
0159936 |
May 1972 |
AUX |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
519192 |
May 1990 |
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