Claims
- 1. A method for inhibiting radiation induced weight and hair loss in an animal receiving radiation treatment comprising administering an effective amount of a Bowman Birk Inhibitor product wherein the Bowman Birk Inhibitor product is produced by the steps consisting essentially of:
- (i) providing soybean solubles produced from acidic aqueous-extracted hexane-defatted soybeans;
- (ii) diluting the soybean solubles with an aqueous solution to form a slurry;
- (iii) separating the aqueous soluble portion of the soybean solubles from the slurry to form a purified soybean soluble composition;
- (iv) diluting the purified soybean soluble composition with an aqueous solution and ultrafiltering the aqueous soluble portion of the diluted purified soybean soluble composition at least once to form a crude Bowman-Birk Inhibitor concentrate; and
- (v) drying the crude Bowman-Birk Inhibitor concentrate to produce a Bowman-Birk Inhibitor concentrate product; to said animal.
- 2. The method of claim 1 wherein said administration is oral.
- 3. The method of claim 1 wherein the drying method used in step (v) is spray drying,
- 4. The method of claim 1 wherein the slurry of step (ii) is a 15 to 20 percent solid solution.
- 5. The method of claim 1 further comprising diluting the crude Bowman-Birk Inhibitor concentrate produced in step (iv) with an aqueous solution and separating a semi-crude Bowman Birk Inhibitor concentrate prior to drying in step (v).
- 6. The method of claim 5 further comprising, prior to the drying step, diluting the semi-crude Bowman-Birk Inhibitor concentrate with acetone and retaining the precipitated acetone insoluble portion.
- 7. The method of claim 6 further comprising lyophilizing the dried Bowman-Birk Inhibitor product.
- 8. A method for inhibiting radiation induced weight and hair loss in an animal receiving radiation treatment comprising administering an effective amount of a Bowman Birk Inhibitor product wherein the Bowman Birk Inhibitor product is produced by the steps consisting essentially of:
- (i) providing soybean solubles from acidic aqueous-extracted hexane-defatted soybeans;
- (ii) diluting the soybean solubles with water and separating a first aqueous soybean soluble portion;
- (iii) adding acetone to the first aqueous portion to produce a first Bowman-Birk Inhibitor precipitate concentrate;
- (iv) diluting the first concentrate with water and separating a second aqueous soybean soluble portion;
- (v) adding acetone to the second aqueous portion to produce a second Bowman-Birk Inhibitor precipitate concentrate;
- (vi) drying the second Bowman-Birk Inhibitor concentrate to produce a Bowman-Birk Inhibitor concentrate product; to said animal.
- 9. The method of claim 8 wherein the drying step is spray drying.
- 10. The method of claim 9 further comprising adding acetone to the second Bowman Birk Inhibitor concentrate prior to the drying step.
- 11. The method of claim 10 further comprising lyophilizing the dried Bowman Birk Inhibitor concentrate product.
INTRODUCTION
This application is a continuation-in-part of Ser. No. 973,335, filed Nov. 2, 1992, now U.S. Pat. No. 5,338,547 which was a continuation-in-part of Ser. No. 824,719 filed Jan. 17, 1992, now U.S. Pat. No. 5,217,717 which was a continuation of Ser. No. 579,155, filed Sep. 6, 1990, now abandoned.
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Continuations (1)
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Date |
Country |
Parent |
579155 |
Sep 1990 |
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Continuation in Parts (2)
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Number |
Date |
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Parent |
973335 |
Nov 1992 |
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Parent |
824719 |
Jan 1992 |
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