Method of manufacturing an electrosurgical forceps

Information

  • Patent Grant
  • 9265569
  • Patent Number
    9,265,569
  • Date Filed
    Thursday, March 29, 2012
    12 years ago
  • Date Issued
    Tuesday, February 23, 2016
    8 years ago
Abstract
A method for manufacturing a jaw assembly configured for use with an electrosurgical forceps is provided. A seal plate with an inwardly facing tab member extending along a peripheral edge thereof is formed. A cavity defined along the inwardly facing tab member of the seal plate is formed. Subsequently, the seal plate is overmolded to a jaw housing. The cavity is configured to receive an insulative substrate therein to facilitate securing the seal plate to the jaw housing.
Description
BACKGROUND

1. Technical Field


The present disclosure relates to an electrosurgical forceps and, more particularly, to a method of manufacturing an end effector assembly including jaw members with seal plates having inwardly facing tab members formed thereon to facilitate overmolding the seal plates to respective jaw housings of the jaw members.


2. Description of Related Art


Electrosurgical forceps are well known in the medical arts. For example, an electrosurgical endoscopic forceps is utilized in surgical procedures, e.g., laparoscopic surgical procedure, where access to tissue is accomplished through a cannula or other suitable device positioned in an opening on a patient. The endoscopic forceps, typically, includes a housing, a handle assembly including a movable handle, a drive assembly, a shaft and an end effector assembly attached to a distal end of the shaft. Typically, the endoscopic forceps utilizes both mechanical clamping action and electrical energy to effect hemostasis by heating the tissue and blood vessels to coagulate, cauterize, seal, cut, desiccate, and/or fulgurate tissue. In particular, the jaw members operably communicate with the drive assembly to manipulate tissue, e.g., grasp and seal tissue and the jaw members have respective seal plates secured to the jaw housing of the respective jaw members to seal tissue.


As is conventional in the endoscopic forceps art, the seal plates are, typically, secured to the respective jaw housing of the respective jaw members via an overmolding process. In particular, a peripheral edge of the seal plate(s) is bent or folded downwards and, subsequently, bent or folded outwards providing a thin lip or tab (referred to in the art as a “pinch trim”) that is overmolded to the jaw housing. As can be appreciated, this results in a thin section of the overmolding that may deform at the high temperatures that are typically associated with an electrosurgical procedure, e.g., an electrosurgical sealing procedure. This deformation of the overmolding may lead to delamination of the of the seal plate from the jaw housing. The delamination of the seal plate from the jaw housing may increase the likelihood of flexure of the jaw members and/or seal plates, which, in turn, may increase the likelihood of the seal plates inadvertently coming into contact with one another resulting in arcs developing therebetween.


In addition to the foregoing, one or more wires are typically secured to the seal plates of the respective jaw members to provide electrosurgical energy thereto. In particular, one (in the case of monopolar endoscopic forceps configurations) or two (in the case of bipolar endoscopic forceps configurations) wires are secured to the seal plates on the respective jaw members via a crimping process. This crimping process is complex and increases manufacturing costs of the electrosurgical instrument. Moreover, this crimping process, e.g., a crimp-on terminal that is positioned on one or both of the seal plates and connects to the respective jaw wire, takes up a large amount of space in the relatively limited space of the jaw members.


SUMMARY

In view of the foregoing, there exists a need in the art for a method of manufacturing an end effector assembly including jaw members with seal plates having inwardly facing tab members formed thereon to facilitate overmolding the seal plates to respective jaw housings of the jaw members.


Embodiments of the present disclosure are described in detail with reference to the drawing figures wherein like reference numerals identify similar or identical elements. As used herein, the term “distal” refers to the portion that is being described which is further from a user, while the term “proximal” refers to the portion that is being described which is closer to a user.


An aspect of the present disclosure provides method for manufacturing a jaw assembly configured for use with an electrosurgical forceps. A seal plate with an inwardly facing tab member extending along a peripheral edge thereof is formed. In certain instances, a jaw wire may be welded to the seal plate. Subsequently, the seal plate is overmolded to a jaw housing. Forming the seal plate may include forming a cavity defined along the inwardly facing tab member of the seal plate. In this instance, the cavity may be configured to receive an insulative substrate therein to facilitate securing the seal plate to the jaw housing.


The insulative substrate may be made from plastic. Forming the seal plate may include forming one or more apertures thereon. In this instance, the aperture(s) is configured to receive the insulative substrate therein such that during the overmolding process of the jaw housing an insulative stop member is formed on the seal plate. The insulative stop member may include a generally arcuate configuration. Forming the seal plate may include forming a plurality of notches along the inwardly facing tab member of the seal plate.


An aspect of the present disclosure provides a method for manufacturing jaw members configured for use with an electrosurgical forceps. One or more of a pair of seal plates is stamped from a sheet metal. The stamped seal plates are formed with an inwardly facing tab member extending along a peripheral edge thereof. In certain instances, a jaw wire may be welded to each of the seal plates. The seal plates are positioned into respective mold cavities. An insulative substrate is introduced into the respective mold cavities. The insulative substrate is allowed to harden in the respective mold cavities to form respective jaw housings with seal plates secured thereto. Forming the seal plates may include forming a cavity defined along the inwardly facing tab member of the seal plate. In this instance, the cavity may be configured to receive the insulative substrate therein to facilitate securing the seal plates to the respective jaw housing. The jaw housings are removed from the respective mold cavities to form a pair of jaw members. The insulative substrate may be made from plastic.


Forming the seal plates may include forming one or more apertures thereon. The aperture(s) may be configured to receive the insulative substrate therein such that during the overmolding process of the respective jaw housing an insulative stop member is formed on the seal plate. The insulative stop member may include a generally arcuate configuration. Forming the seal plates may include forming a plurality of notches along the inwardly facing tab member of the seal plate.


An aspect of the present disclosure provides a method for manufacturing jaw members configured for use with an electrosurgical forceps. A pair of seal plates is stamped from sheet metal. The stamped seal plates may be formed with an inwardly facing tab member extending along a peripheral edge thereof, and one or more apertures thereon. A cavity defined along the inwardly facing tab member of the seal plate is formed. The seal plates are positioned into respective mold cavities. An insulative substrate is introduced into the respective mold cavities. The insulative substrate is allowed to harden in the respective mold cavities to form respective jaw housings with seal plates secured thereto. The cavities are defined along the inwardly facing tab members of the seal plates and are configured to receive the insulative substrate therein to facilitate securing the seal plates to a respective jaw housing. The aperture(s) is configured to receive the insulative substrate therein such that an insulative stop member is formed on the seal plate. The jaw housings is removed from the respective mold cavities to form a pair of jaw members.





BRIEF DESCRIPTION OF THE DRAWING

Various embodiments of the present disclosure are described hereinbelow with references to the drawings, wherein:



FIG. 1 is a perspective view of an endoscopic electrosurgical forceps utilizing an end effector including jaw members manufactured according to an embodiment of the present disclosure;



FIG. 2 is a cross-sectional view of a pair of opposing seal plates of the jaw members depicted in FIG. 1 with a corresponding jaw housings illustrated in phantom;



FIG. 3 is a plan view of the lower seal plate depicted in FIG. 2 illustrating a connection point between the seal plate and a jaw wire of the endoscopic electrosurgical forceps;



FIG. 4 a plan view of a seal plate configured for use with the jaw members depicted in FIG. 1 according to an embodiment of the present disclosure;



FIG. 5 is a cross-sectional view of the seal plate depicted in FIG. 4 taken along line segment 5-5 with the corresponding jaw housing illustrated in phantom; and



FIG. 6 is a plan view of a seal plate configured for use with the jaw members depicted in FIG. 1 according to another embodiment of the present disclosure.





DETAILED DESCRIPTION

Detailed embodiments of the present disclosure are disclosed herein; however, the disclosed embodiments are merely examples of the disclosure, which may be embodied in various forms. Therefore, specific structural and functional details disclosed herein are not to be interpreted as limiting, but merely as a basis for the claims and as a representative basis for teaching one skilled in the art to variously employ the present disclosure in virtually any appropriately detailed structure.


Turning now to FIG. 1, an electrosurgical endoscopic forceps 10 (forceps 10) is provided having a longitudinal axis “A-A” defined therethrough, a housing 20, a handle assembly 30, a rotating assembly 70, a trigger assembly 80 and an end effector assembly 100. Forceps 10 further includes a shaft 12 having a distal end 14 configured to mechanically engage end effector assembly 100 and a proximal end 16 that mechanically engages housing 20. Forceps 10 also includes electrosurgical cable 610 that connects forceps 10 to a generator (not shown) or other suitable power source. Alternately, forceps 10 may be configured as a battery powered instrument. Cable 610 includes one or more wires 611 (one wire shown in the drawings) extending therethrough that has sufficient length to extend through shaft 12 in order to provide electrical energy to one or both of the jaw members 110 and 120 of end effector assembly 100.


Continuing with reference to FIG. 1, end effector assembly 100 is designed as a unilateral assembly, e.g., where jaw member 120 is fixed relative to shaft 12 and jaw member 110 is moveable about pivot 103 relative to shaft 12 and fixed jaw member 120. However, end effector assembly 100 may alternatively be configured as a bilateral assembly, e.g., where both jaw member 110 and jaw member 120 are moveable about a pivot 103 relative to one another and to shaft 12. In some embodiments, a knife assembly (not explicitly shown) is disposed within shaft 12 and a knife channel (not explicitly shown) is defined within one or both jaw members 110, 120 to permit reciprocation of a knife blade (not explicitly shown) therethrough, e.g., via an activation of trigger 82 (FIG. 1) of trigger assembly 80.


Other than jaw member 110 being movable and jaw member 120 being stationary, jaw members 110 and 120 are identical to one another. In view thereof, and unless otherwise noted, jaw member 120 is described in detail hereinafter.


Turning now to FIG. 2, jaw member 120 is illustrated including a jaw housing 124 (shown in phantom). Jaw housing 124 may be made from any suitable material including, but not limited to, plastic (e.g., thermoplastic, thermosetting plastic, etc.), ceramic material, etc. In the illustrated embodiment, jaw housing 124 is made from thermosetting plastic that serves as an insulative substrate, described in more detail below. In certain instances, it may prove advantageous to provide an exterior portion of the jaw housing 124 that is made from metal and an interior portion (e.g., a portion that is configured to support the seal plate 122 thereon) of the jaw housing 124 that made from plastic. In this instance, the interior portion serves as an insulative barrier between the seal plate 122 and the exterior portion of the jaw housing 124.


Continuing with reference to FIG. 2, jaw member 120 includes electrically conductive tissue sealing plate 122. Seal plate 122 may be made via any suitable manufacturing process including a machining process, a stamping process or the like. In the illustrated embodiment seal plate 122 is made via a stamping process and, subsequently, overmolded to jaw housing 124. A stamping or machine press (not shown) may be utilized to cut or “punch” sheet-metal to a desired configuration. Subsequently, the stamping press is utilized to shape the “punched” sheet-metal into one or more suitable configurations by deforming it with a die or other suitable device (not shown). The aforementioned stamping process may include a variety of other sheet-metal manufacturing processes, such as, for example, blanking, embossing, bending, flanging, and coining.


In accordance with the instant disclosure, the seal plate 122 is formed with an inwardly facing tab member 126 (FIG. 2) that extends along a peripheral edge 128 of the seal plate 122 (FIGS. 2 and 3). Inwardly facing tab member 126 is configured to facilitate securing the seal plate 122 to the jaw housing 124 during a manufacturing process of the jaw member 120. In particular, a cavity or channel 130 (FIG. 2) is defined along the inwardly facing tab 126 member and is configured to receive the liquid thermosetting plastic therein. More particularly, during manufacture of the jaw member 120, seal plate 122 is positioned within a mold cavity (not explicitly shown) that is configured to support the seal plate 122 therein and shaped to correspond to a desired jaw housing configuration. Subsequently, liquid thermosetting plastic is introduced into the mold cavity to form the jaw housing 124. The cavity 130 of the inwardly facing tab member 126 is configured to receive the liquid thermosetting plastic therein such that when the thermosetting plastic cures, the seal plate 122 firmly secures to the formed jaw housing 124.


The liquid thermosetting plastic may be heated and/or mixed prior to being introduced into the mold cavity. A “single-shot” or “two-shot” injection molding process may be utilized to introduce the liquid thermosetting plastic into the mold cavity.


Jaw member 110 includes an opposing electrically conductive tissue sealing plate 112 including an inwardly facing tab member 127 that extends along a peripheral edge 129 of the seal plate 112 (FIG. 2). Similar to that of cavity 130 of inwardly facing tab member 126, a cavity 131 of the inwardly facing tab member 127 facilitates securing the seal plate 112 to a jaw housing 114 (FIG. 2).


With reference to FIG. 3, wire 611 is operably coupled to the seal plate 122. More particularly, and unlike conventional forceps that utilize a crimping process to couple a jaw wire to a seal plate, wire 611 of the forceps 10 is coupled to the seal plate 122 via a spot welding process, ultrasonic welding process or the like. One of these welding processes e.g., spot welding, is utilized to secure wire 611 to the seal plate 122 prior to the seal plate 122 being positioned within the mold cavity. As can be appreciated, this overcomes the aforementioned drawbacks described above with respect to conventional forceps. That is, the spot welding process is an inexpensive and relatively easy manufacturing method that secures the wire 611 to the seal plate 122, as opposed to the crimping process that typically utilizes crimp-on terminals to secure wires to the seal plates of conventional forceps. The aforementioned spot welding process may be utilized to secure another wire (not explicitly shown) to the seal plate 112.


In embodiments, it may prove advantageous to provide one or more insulative or non-conductive stop members on one or both of the seal plates 112 and 122. In accordance with the present disclosure, either of seal plates 112 or 122 may be formed with one or more apertures 132 of suitable configuration (FIG. 4). For illustrative purposes, six (6) apertures 132 are shown formed on seal plate 122. Apertures 132 are configured to receive the liquid thermosetting plastic therein such that during the manufacturing process of the jaw housing 124, an insulative stop member(s) 134 forms on the seal plate 122 of the jaw member 120 (FIG. 5). In particular, during the molding process of the jaw housing 124, the liquefied thermosetting plastic seeps or flows through the apertures 132 and cures on a seal surface of the seal plate 122 as the jaw housing 124 cures. In the illustrated embodiment, the cured stop members 134 include a generally arcuate configuration having a dimple or mushroom like profile (as best see in FIG. 5), although other configurations are contemplated.


The stop members 134 function similar to that of stop members that are typically associated with conventional forceps. That is, the stop members 134 may provide a specific gap distance between the jaw members 110 and 120 when the jaw members 110 and 120 are in the clamping configuration. Moreover, the stop members 134 may function to prevent the seal plates 112 and 122 from touching one another during the transmission of electrosurgical energy to the jaw members 110 and 120. In embodiments, the gap distance may range from about 0.001 inches to about 0.0016 inches. Unlike conventional stop members that are typically glued to seal plates via one or more suitable adhesives, and which are prone to becoming dislodged from the seal plates under high shear forces, the stop members 134 of the instant disclosure are formed with the jaw housing 124 and, thus, are permanently affixed to the seal surface of the seal plate 122. Therefore, the likelihood of the stop members 134 becoming dislodged from the seal surface of the seal plate 124 is diminished, if not eliminated.


In embodiment, where each of the seal plates 112 and 122 includes stop members 134, the stop members 134 on the seal plates 112 and 122 may be in vertical registration with one another.


In certain embodiments, after the jaw housing 124 and/or stop members 134 have cured, a buffing machine or the like may be utilized to smooth out rough edges that may have formed during the curing process.


In use, tissue may be positioned between the jaw members 110 and 120. Subsequently, electrosurgical energy is transmitted to the seal plates 112 and 122 via wires 611. The unique configuration of the seal plates 112, 122 including the respective inwardly facing tab members 127, 126 associated therewith overcome the aforementioned drawbacks typically associated with conventional forceps. That is, the inwardly facing tab members 127, 126 including the respective cavities 131, 130 defined therein provides a greater point of contact between the jaw housings 114, 124 and seal plates 112, 122, and, thus, the likelihood of the seal plates 112, 122 delaminating adjacent the point of contact between the seal plates 112, 122 and jaw housings 114, 124 is diminished, if not eliminated.


From the foregoing and with reference to the various figure drawings, those skilled in the art will appreciate that certain modifications can also be made to the present disclosure without departing from the scope of the same. For example, in certain instances, it may prove advantageous to secure the seal plates 112 and 122 to the respective jaw housing 114, 124 of the jaw members 110 and 120 via a different securement method.


With reference to FIG. 6 a plan view of a seal plate according to an alternate embodiment is shown designated as a seal plate 222. Seal plate 222 is similar to that of seal plate 122, however, unlike seal plate 122 that includes an inwardly facing tab member 126, seal plate 222 includes an outwardly facing tab member 226. Unlike conventional seal plates that utilize outwardly facing tab members, outwardly facing tab member 226 includes one or more notches 228. Notches 228 allow for local, thicker wall section (not explicitly shown) that adds strength to the jaw housing (not explicitly shown). As with the cavity 130 defined in the inwardly facing tab member 126, the notches 228 of the outwardly facing tab member 226 are configured to receive the liquid thermosetting plastic therein. When the liquid thermosetting plastic cures, the seal plate 222 is firmly secured to the jaw housing. (from the invention disclosure, it is not readily apparent where the notches are located on the seal plate)


The unique configuration of the seal plate 222 including the outwardly facing tab member 226 associated therewith overcomes the aforementioned drawbacks typically associated with conventional forceps. That is, the outwardly facing tab member 226 including the notches 228 defined therein provide a greater point of contact between the jaw housing and seal plate 222, and, thus, the likelihood of the seal plate 222 delaminating adjacent the point of contact between the seal plate 222 and jaw housing is diminished, if not eliminated.


In another embodiment, one or both of the inwardly facing tab members 126, 127 may include one or more of the notches 228 thereon.


While several embodiments of the disclosure have been shown in the drawings, it is not intended that the disclosure be limited thereto, as it is intended that the disclosure be as broad in scope as the art will allow and that the specification be read likewise. Therefore, the above description should not be construed as limiting, but merely as exemplifications of particular embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the claims appended hereto.

Claims
  • 1. A method for manufacturing a jaw member configured for use with an electrosurgical forceps, comprising: forming a seal plate defining a central longitudinal axis and a sealing surface;forming a cavity opposite the sealing surface by bending a peripheral edge of the seal plate substantially perpendicular to the sealing surface to define a tab and bending a portion of the tab toward the longitudinal axis substantially parallel to the sealing surface, wherein forming the cavity includes forming the cavity between the tab and another portion of the seal plate; andsecuring the seal plate to a jaw housing by receiving an insulative substrate within the cavity during an overmolding process to form the jaw member configured for use with an electrosurgical forceps.
  • 2. The method according to claim 1, wherein forming the seal plate includes forming at least one aperture thereon.
  • 3. The method according to claim 2, wherein the at least one aperture is configured to receive the insulative substrate therein such that during the overmolding process of the jaw housing an insulative stop member is formed on the seal plate.
  • 4. The method according to claim 3, wherein the insulative stop member includes a generally arcuate configuration.
  • 5. The method according to claim 1, further comprising welding a wire to the seal plate.
  • 6. The method according to claim 1, wherein the insulative substrate is made from plastic.
  • 7. A method for manufacturing jaw members configured for use with an electrosurgical forceps, comprising: stamping at least one pair of seal plates from sheet metal, each of the seal plates defining a central longitudinal axis and a sealing surface;forming, on each of the seal plates, a cavity opposite the sealing surface by bending a peripheral edge of each of the seal plates substantially perpendicular to the sealing surface to define a tab and bending a portion of the tab toward the central longitudinal axis substantially parallel to the sealing surface, wherein forming the cavity includes forming the cavity between the tab and another portion of the seal plate;positioning the seal plates into respective mold cavities;introducing an insulative substrate into the respective mold cavities such that the insulative substrate is received within the respective formed cavity;allowing the insulative substrate to harden in the respective mold cavities to form respective jaw housings with respective seal plates secured thereto, wherein the respective formed cavity is configured to receive the insulative substrate therein to facilitate securing the respective seal plate to the respective jaw housing; andremoving the jaw housings from the respective mold cavities to form at least a pair of jaw members configured for use with an electrosurgical forceps.
  • 8. The method according to claim 7, wherein forming the seal plates includes forming at least one aperture thereon.
  • 9. The method according to claim 8, wherein the at least one aperture is configured to receive the insulative substrate therein such that during an overmolding process of the respective jaw housing an insulative stop member is formed on the seal plate.
  • 10. The method according to claim 9, wherein the insulative stop member includes a generally arcuate configuration.
  • 11. The method according to claim 7, further comprising welding a wire to each of the seal plates.
  • 12. The method according to claim 7, wherein the insulative substrate is made from plastic.
  • 13. A method for manufacturing jaw members configured for use with an electrosurgical forceps, comprising: stamping at least one pair of seal plates from sheet metal, each of the seal plates defining a central longitudinal axis and a sealing surface;forming, on each of the seal plates, a cavity opposite the sealing surface by bending a peripheral edge of each of the seal plates substantially perpendicular to the sealing surface to define a tab and bending a portion of the tab toward the central longitudinal axis substantially parallel to the surface, wherein forming the cavity includes forming the cavity between the tab and another portion of the seal plate;positioning the seal plates into respective mold cavities;introducing an insulative substrate into each of the respective mold cavities such that the insulative substrate is received within the respective formed cavity;allowing the insulative substrate to harden in the respective mold cavities to form respective jaw housings with respective seal plates secured thereto, wherein each formed cavity is configured to receive the insulative substrate therein to facilitate securing the respective seal plates to the respective jaw housings, and wherein the at least one aperture is configured to receive the insulative substrate therein such that an insulative stop member is formed on the seal plate; andremoving the jaw housings from the respective mold cavities to form a pair of jaw members configured for use with an electrosurgical forceps.
US Referenced Citations (79)
Number Name Date Kind
D249549 Pike Sep 1978 S
D263020 Rau, III Feb 1982 S
D295893 Sharkany et al. May 1988 S
D295894 Sharkany et al. May 1988 S
D298353 Manno Nov 1988 S
D299413 Decarolis Jan 1989 S
D343453 Noda Jan 1994 S
D348930 Olson Jul 1994 S
D349341 Lichtman et al. Aug 1994 S
D354564 Medema Jan 1995 S
D358887 Feinberg May 1995 S
D384413 Zlock et al. Sep 1997 S
H1745 Paraschac Aug 1998 H
D402028 Grimm et al. Dec 1998 S
D408018 McNaughton Apr 1999 S
D416089 Barton et al. Nov 1999 S
D424694 Tetzlaff et al. May 2000 S
D425201 Tetzlaff et al. May 2000 S
H1904 Yates et al. Oct 2000 H
D449886 Tetzlaff et al. Oct 2001 S
D453923 Olson Feb 2002 S
D454951 Bon Mar 2002 S
D457958 Dycus et al. May 2002 S
D457959 Tetzlaff et al. May 2002 S
H2037 Yates et al. Jul 2002 H
D465281 Lang Nov 2002 S
D466209 Bon Nov 2002 S
D493888 Reschke Aug 2004 S
D496997 Dycus et al. Oct 2004 S
D499181 Dycus et al. Nov 2004 S
D502994 Blake, III Mar 2005 S
6908463 Treat et al. Jun 2005 B2
D509297 Wells Sep 2005 S
D525361 Hushka Jul 2006 S
D531311 Guerra et al. Oct 2006 S
7135020 Lawes et al. Nov 2006 B2
D533274 Visconti et al. Dec 2006 S
D533942 Kerr et al. Dec 2006 S
7147638 Chapman et al. Dec 2006 B2
D535027 James et al. Jan 2007 S
7160299 Baily Jan 2007 B2
D538932 Malik Mar 2007 S
D541418 Schechter et al. Apr 2007 S
D541611 Aglassinger May 2007 S
D541938 Kerr et al. May 2007 S
D545432 Watanabe Jun 2007 S
D547154 Lee Jul 2007 S
D564662 Moses et al. Mar 2008 S
D567943 Moses et al. Apr 2008 S
7396265 Darley et al. Jul 2008 B2
7396356 Mollenauer Jul 2008 B2
D575395 Hushka Aug 2008 S
D575401 Hixson et al. Aug 2008 S
D582038 Swoyer et al. Dec 2008 S
7668597 Engmark et al. Feb 2010 B2
D617900 Kingsley et al. Jun 2010 S
D617901 Unger et al. Jun 2010 S
D617902 Twomey et al. Jun 2010 S
D617903 Unger et al. Jun 2010 S
D618798 Olson et al. Jun 2010 S
D621503 Otten et al. Aug 2010 S
D627462 Kingsley Nov 2010 S
D628289 Romero Nov 2010 S
D628290 Romero Nov 2010 S
D630324 Reschke Jan 2011 S
7877853 Unger et al. Feb 2011 B2
D649249 Guerra Nov 2011 S
D649643 Allen, IV et al. Nov 2011 S
20030216733 McClurken et al. Nov 2003 A1
20050021026 Baily Jan 2005 A1
20060141861 Darley et al. Jun 2006 A1
20080058802 Couture et al. Mar 2008 A1
20080195093 Couture et al. Aug 2008 A1
20080208289 Darley et al. Aug 2008 A1
20090082769 Unger et al. Mar 2009 A1
20090216229 Chojin Aug 2009 A1
20100179543 Johnson et al. Jul 2010 A1
20100204697 Dumbauld et al. Aug 2010 A1
20100204698 Chapman et al. Aug 2010 A1
Foreign Referenced Citations (67)
Number Date Country
201299462 Sep 2009 CN
2415263 Oct 1975 DE
2514501 Oct 1976 DE
2627679 Jan 1977 DE
3423356 Jun 1986 DE
3612646 Apr 1987 DE
8712328 Mar 1988 DE
4303882 Aug 1994 DE
4403252 Aug 1995 DE
19515914 Jul 1996 DE
19506363 Aug 1996 DE
29616210 Jan 1997 DE
19608716 Apr 1997 DE
19751106 May 1998 DE
19751108 May 1999 DE
19946527 Dec 2001 DE
10045375 Oct 2002 DE
10 2004 026179 Dec 2005 DE
20 2007 009165 Oct 2007 DE
20 2007 009317 Oct 2007 DE
20 2007 016233 Mar 2008 DE
19738457 Jan 2009 DE
10 2008 018406 Jul 2009 DE
1159926 Dec 2001 EP
61-501068 Sep 1984 JP
6-502328 Mar 1992 JP
5-5106 Jan 1993 JP
5-40112 Feb 1993 JP
6-030945 Feb 1994 JP
6-121797 May 1994 JP
6-285078 Oct 1994 JP
6-343644 Dec 1994 JP
6-511401 Dec 1994 JP
7-265328 Oct 1995 JP
8-56955 Mar 1996 JP
8-317936 Mar 1996 JP
8-289895 May 1996 JP
8-252263 Oct 1996 JP
8-317934 Dec 1996 JP
9-10223 Jan 1997 JP
9-122138 May 1997 JP
10-24051 Jan 1998 JP
11-070124 May 1998 JP
10-155798 Jun 1998 JP
2000-102545 Sep 1998 JP
11-47150 Feb 1999 JP
11-169381 Jun 1999 JP
11-192238 Jul 1999 JP
11-244298 Sep 1999 JP
2000-342599 Dec 2000 JP
2000-350732 Dec 2000 JP
2001-8944 Jan 2001 JP
2001-29356 Feb 2001 JP
2001-128990 May 2001 JP
2001-190564 Jul 2001 JP
2001-3400 Nov 2001 JP
2002-528166 Mar 2002 JP
2003-245285 Sep 2003 JP
2004-517668 Jun 2004 JP
2004-528869 Sep 2004 JP
2011-125195 Jun 2011 JP
401367 Nov 1974 SU
WO 0036986 Jun 2000 WO
WO 0059392 Oct 2000 WO
WO 0115614 Mar 2001 WO
WO 0154604 Aug 2001 WO
WO 2005110264 Nov 2005 WO
Non-Patent Literature Citations (270)
Entry
U.S. Appl. No. 08/926,869, filed Sep. 10, 1997, James G. Chandler.
U.S. Appl. No. 09/177,950, filed Oct. 23, 1998, Randel A. Frazier.
U.S. Appl. No. 09/387,883, filed Sep. 1, 1999, Dale F. Schmaltz.
U.S. Appl. No. 09/591,328, filed Jun. 9, 2000, Thomas P. Ryan.
U.S. Appl. No. 12/336,970, filed Dec. 17, 2008, Paul R. Sremeich.
U.S. Appl. No. 12/915,809, filed Oct. 29, 2010, Thomas J. Gerhardt, Jr.
U.S. Appl. No. 12/947,352, filed Nov. 16, 2010, Jason L. Craig.
U.S. Appl. No. 12/947,420, filed Nov. 16, 2010, Jason L. Craig.
U.S. Appl. No. 12/948,081, filed Nov. 17, 2010, Boris Chernov.
U.S. Appl. No. 12/948,144, filed Nov. 17, 2010, Boris Chernov.
U.S. Appl. No. 12/950,505, filed Nov. 19, 2010, David M. Garrison.
U.S. Appl. No. 12/955,010, filed Nov. 29, 2010, Paul R. Romero.
U.S. Appl. No. 12/955,042, filed Nov. 29, 2010, Steven C. Rupp.
U.S. Appl. No. 12/981,771, filed Dec. 30, 2010, James D. Allen, IV.
U.S. Appl. No. 12/981,787, filed Dec. 30, 2010, John R. Twomey.
U.S. Appl. No. 13/006,538, filed Jan. 14, 2011, John W. Twomey.
U.S. Appl. No. 13/028,810, filed Feb. 16, 2011, Robert M. Sharp.
U.S. Appl. No. 13/030,231, filed Feb. 18, 2011, Jeffrey M. Roy.
U.S. Appl. No. 13/050,182, filed Mar. 17, 2011, Glenn A. Horner.
U.S. Appl. No. 13/072,945, filed Mar. 28, 2011, Patrick L. Dumbauld.
U.S. Appl. No. 13/080,383, filed Apr. 5, 2011, David M. Garrison.
U.S. Appl. No. 13/085,144, filed Apr. 12, 2011, Keir Hart.
U.S. Appl. No. 13/089,779, filed Apr. 19, 2011, Yevgeniy Fedotov.
U.S. Appl. No. 13/091,331, filed Apr. 21, 2011, Jeffrey R. Townsend.
U.S. Appl. No. 13/102,573, filed May 6, 2011, John R. Twomey.
U.S. Appl. No. 13/102,604, filed May 6, 2011, Paul E. Ourada.
U.S. Appl. No. 13/108,093, filed May 16, 2011, Boris Chernov.
U.S. Appl. No. 13/108,129, filed May 16, 2011, Boris Chernov.
U.S. Appl. No. 13/108,152, filed May 16, 2011, Boris Chernov.
U.S. Appl. No. 13/108,177, filed May 16, 2011, Boris Chernov.
U.S. Appl. No. 13/108,196, filed May 16, 2011, Boris Chernov.
U.S. Appl. No. 13/108,441, filed May 16, 2011, Boris Chernov.
U.S. Appl. No. 13/108,468, filed May 16, 2011, Boris Chernov.
U.S. Appl. No. 13/111,642, filed May 19, 2011, John R. Twomey.
U.S. Appl. No. 13/111,678, filed May 19, 2011, Nikolay Kharin.
U.S. Appl. No. 13/113,231, filed May 23, 2011, David M. Garrison.
U.S. Appl. No. 13/157,047, filed Jun. 9, 2011, John R. Twomey.
U.S. Appl. No. 13/162,814, filed Jun. 17, 2011, Barbara R. Tyrrell.
U.S. Appl. No. 13/166,477, filed Jun. 22, 2011, Daniel A. Joseph.
U.S. Appl. No. 13/166,497, filed Jun. 22, 2011, Daniel A. Joseph.
U.S. Appl. No. 13/179,919, filed Jul. 11, 2011, Russell D. Hempstead.
U.S. Appl. No. 13/179,960, filed Jul. 11, 2011, Boris Chernov.
U.S. Appl. No. 13/179,975, filed Jul. 11, 2011, Grant T. Sims.
U.S. Appl. No. 13/180,018, filed Jul. 11, 2011, Chase Collings.
U.S. Appl. No. 13/183,856, filed Jul. 15, 2011, John R. Twomey.
U.S. Appl. No. 13/185,593, filed Jul. 19, 2011, James D. Allen, IV.
U.S. Appl. No. 13/204,841, filed Aug. 8, 2011, Edward J. Chojin.
U.S. Appl. No. 13/205,999, filed Aug. 9, 2011, Jeffrey R. Unger.
U.S. Appl. No. 13/212,297, filed Aug. 18, 2011, Allan J. Evans.
U.S. Appl. No. 13/212,308, filed Aug. 18, 2011, Allan J. Evans.
U.S. Appl. No. 13/212,329, filed Aug. 18, 2011, Allan J. Evans.
U.S. Appl. No. 13/212,343, filed Aug. 18, 2011, Duane E. Kerr.
U.S. Appl. No. 13/223,521, filed Sep. 1, 2011, John R. Twomey.
U.S. Appl. No. 13/227,220, filed Sep. 7, 2011, James D. Allen, IV.
U.S. Appl. No. 13/228,742, filed Sep. 9, 2011, Duane E. Kerr.
U.S. Appl. No. 13/231,643, filed Sep. 13, 2011, Keir Hart.
U.S. Appl. No. 13/234,357, filed Sep. 16, 2011, James D. Allen, IV.
U.S. Appl. No. 13/236,168, filed Sep. 19, 2011, James D. Allen, IV.
U.S. Appl. No. 13/236,271, filed Sep. 19, 2011, Monte S. Fry.
U.S. Appl. No. 13/243,628, filed Sep. 23, 2011, William Ross Whitney.
U.S. Appl. No. 13/247,778, filed Sep. 28, 2011, John R. Twomey.
U.S. Appl. No. 13/247,795, filed Sep. 28, 2011, John R. Twomey.
U.S. Appl. No. 13/248,976, filed Sep. 29, 2011, James D. Allen, IV.
U.S. Appl. No. 13/249,013, filed Sep. 29, 2011, Jeffrey R. Unger.
U.S. Appl. No. 13/249,024, filed Sep. 29, 2011, John R. Twomey.
U.S. Appl. No. 13/251,380, filed Oct. 3, 2011, Duane E. Kerr.
U.S. Appl. No. 13/277,373, filed Oct. 20, 2011, Glenn A. Homer.
U.S. Appl. No. 13/277,926, filed Oct. 20, 2011, David M. Garrison.
U.S. Appl. No. 13/277,962, filed Oct. 20, 2011, David M. Garrison.
U.S. Appl. No. 13/293,754, filed Nov. 10, 2011, Jeffrey M. Roy.
U.S. Appl. No. 13/306,523, filed Nov. 29, 2011, David M. Garrison.
U.S. Appl. No. 13/306,553, filed Nov. 29, 2011, Duane E. Kerr.
U.S. Appl. No. 13/308,104, filed Nov. 30, 2011, John R. Twomey.
U.S. Appl. No. 13/312,172, filed Dec. 6, 2011, Robert J. Behnke, II.
U.S. Appl. No. 13/324,863, filed Dec. 13, 2011, William H. Nau, Jr.
U.S. Appl. No. 13/344,729, filed Jan. 6, 2012, James D. Allen, IV.
U.S. Appl. No. 13/355,829, filed Jan. 23, 2012, John R.Twomey.
U.S. Appl. No. 13/357,979, filed Jan. 25, 2012, David M. Garrison.
U.S. Appl. No. 13/358,136, filed Jan. 25, 2012, James D. Allen, IV.
U.S. Appl. No. 13/358,657, filed Jan. 26, 2012, Kim V. Brandt.
U.S. Appl. No. 13/360,925, filed Jan. 30, 2012, James H. Orszulak.
U.S. Appl. No. 13/369,152, filed Feb. 8, 2012, William H. Nau, Jr.
U.S. Appl. No. 13/400,290, filed Feb. 20, 2012, Eric R. Larson.
U.S. Appl. No. 13/401,964, filed Feb. 22, 2012, John R. Twomey.
U.S. Appl. No. 13/404,435, filed Feb. 24, 2012, Kim V. Brandt.
U.S. Appl. No. 13/404,476, filed Feb. 24, 2012, Kim V. Brandt.
Michael Choti, “Abdominoperineal Resection with the LigaSure Vessel Sealing System and LigaSure Atlas 20 cm Open Instrument”; Innovations That Work, Jun. 2003.
Chung et al., “Clinical Experience of Sutureless Closed Hemorrhoidectomy with LigaSure” Diseases of the Colon & Rectum vol. 46, No. 1 Jan. 2003.
Tinkcler L.F., “Combined Diathermy and Suction Forceps”, Feb. 6, 1967 (Feb. 6, 1965), British Medical Journal Feb. 6, 1976, Vol. 1, nr. 5431 p. 361, ISSN: 0007-1447.
Carbonell et al., “Comparison of theGyrus PlasmaKinetic Sealer and the Valleylab LigaSure Device in the Hemostasis of Small, Medium, and Large-Sized Arteries” Carolinas Laparoscopic and Advanced Surgery Program, Carolinas Medical Center, Charlotte, NC; Date: Aug. 2003.
Peterson et al. “Comparison of Healing Process Following Ligation with Sutures and Bipolar Vessel Sealing” Surgical Technology International (2001).
“Electrosurgery: A Historical Overview” Innovations in Electrosurgery; Sales/Product Literature; Dec. 31, 2000.
Johnson et al. “Evaluation of a Bipolar Electrothermal Vessel Sealing Device in Hemorrhoidectomy” Sales/Product Literature; Jan. 2004.
E. David Crawford “Evaluation of a New Vessel Sealing Device in Urologic Cancer Surgery” Sales/Product Literature 2000.
Johnson et al. “Evaluation of the LigaSure Vessel Sealing System in Hemorrhoidectormy” American College of Surgeons (ACS) Clinicla Congress Poster (2000).
Muller et al., “Extended Left Hemicolectomy Using the LigaSure Vessel Sealing System” Innovations That Work, Sep. 1999.
Kennedy et al. “High-burst-strength, feedback-controlled bipolar vessel sealing” Surgical Endoscopy (1998) 12: 876-878.
Burdette et al. “In Vivo Probe Measurement Technique for Determining Dielectric Properties at VHF Through Microwave Frequencies”, IEEE Transactions on Microwave Theory and Techniques, vol. MTT-28, No. 4, Apr. 1980 pp. 414-427.
Carus et al., “Initial Experience With the LigaSure Vessel Sealing System in Abdominal Surgery” Innovations That Work, Jun. 2002.
Heniford et al. “Initial Research and Clinical Results with an Electrothermal Bipolar Vessel Sealer” Oct. 1999.
Heniford et al. “Initial Results with an Electrothermal Bipolar Vessel Sealer” Surgical Endoscopy (2000) 15:799-801.
Herman et al., “Laparoscopic Intestinal Resection With the LigaSure Vessel Sealing System: A Case Report”; Innovations That Work, Feb. 2002.
Koyle et al., “Laparoscopic Palomo Varicocele Ligation in Children and Adolescents” Pediatric Endosurgery & Innovative Techniques, vol. 6, No. 1, 2002.
W. Scott Helton, “LigaSure Vessel Sealing System: Revolutionary Hemostasis Product for General Surgery”; Sales/Product Literature 1999.
LigaSure Vessel Sealing System, the Seal of Confidence in General, Gynecologic, Urologic, and Laparaoscopic Surgery; Sales/Product Literature; Apr. 2002.
Joseph Ortenberg “LigaSure System Used in Laparoscopic 1st and 2nd Stage Orchiopexy” Innovations That Work, Nov. 2002.
Sigel et al. “The Mechanism of Blood Vessel Closure by High Frequency Electrocoagulation” Surgery Gynecology & Obstetrics, Oct. 1965 pp. 823-831.
Sampayan et al, “Multilayer Ultra-High Gradient Insulator Technology” Discharges and Electrical Insulation in Vacuum, 1998. Netherlands Aug. 17-21, 1998; vol. 2, pp. 740-743.
Paul G. Horgan, “A Novel Technique for Parenchymal Division During Hepatectomy” The American Journal of Surgery, vol. 181, No. 3, Apr. 2001 pp. 236-237.
Benaron et al., “Optical Time-of-Flight and Absorbance Imaging of Biologic Media”, Science, American Association for the Advancement of Science, Washington, DC, vol. 259, Mar. 5, 1993, pp. 1463-1466.
Olsson et al. “Radical Cystectomy in Females” Current Surgical Techniques in Urology, vol. 14, Issue 3, 2001.
Palazzo et al. “Randomized clinical trial of Ligasure versus open haemorrhoidectomy” British Journal of Surgery 2002, 89, 154-157.
Levy et al. “Randomized Trial of Suture Versus Electrosurgical Bipolar Vessel Sealing in Vaginal Hysterectomy” Obstetrics & Gynecology, vol. 102, No. 1, Jul. 2003.
“Reducing Needlestick Injuries in the Operating Room” Sales/Product Literature 2001.
Bergdahl et al. “Studies on Coagulation and the Development of an Automatic Computerized Bipolar Coagulator” J.Neurosurg, vol. 75, Jul. 1991, pp. 148-151.
Strasberg et al. “A Phase I Study of the LigaSure Vessel Sealing System in Hepatic Surgery” Section of HPB Surger, Washington University School of Medicine, St. Louis MO, Presented at AHPBA, Feb. 2001.
Sayfan et al. “Sutureless Closed Hemorrhoidectomy: A New Technique” Annals of Surgery vol. 234 No. 1 Jul. 2001; pp. 21-24.
Levy et al., “Update on Hysterectomy—New Technologies and Techniques” OBG Management, Feb. 2003.
Dulemba et al. “Use of a Bipolar Electrothermal Vessel Sealer in Laparoscopically Assisted Vaginal Hysterectomy” Sales/Product Literature; Jan. 2004.
Strasberg et al., “Use of a Bipolar Vessel-Sealing Device for Parenchymal Transection During Liver Surgery” Journal of Gastrointestinal Surgery, vol. 6, No. 4, Jul./Aug. 2002 pp. 569-574.
Sengupta et al., “Use of a Computer-Controlled Bipolar Diathermy System in Radical Prostatectomies and Other Open Urological Surgery” ANZ Journal of Surgery (2001) 71.9 pp. 538-540.
Rothenberg et al. “Use of the LigaSure Vessel Sealing System in Minimally Invasive Surgery in Children” Int'l Pediatric Endosurgery Group (IPEG) 2000.
Crawford et al. “Use of the LigaSure Vessel Sealing System in Urologic Cancer Surgery” Grand Rounds in Urology 1999 vol. 1 Issue 4 pp. 10-17.
Craig Johnson, “Use of the LigaSure Vessel Sealing System in Bloodless Hemorrhoidectomy” Innovations That Work, Mar. 2000.
Levy et al. “Use of a New Energy-based Vessel Ligation Device During Vaginal Hysterectomy” Int'l Federation of Gynecology and Obstetrics (FIGO) World Congress 1999.
Barbara Levy, “Use of a New Vessel Ligation Device During Vaginal Hysterectomy” FIGO 2000, Washington, D.C.
E. David Crawford “Use of a Novel Vessel Sealing Technology in Management of the Dorsal Veinous Complex” Sales/Product Literature 2000.
Jarrett et al., “Use of the LigaSure Vessel Sealing System for Peri-Hilar Vessels in Laparoscopic Nephrectomy” Sales/Product Literature 2000.
Crouch et al. “A Velocity-Dependent Model for Needle Insertion in Soft Tissue” MICCAI 2005; LNCS 3750 pp. 624-632, Dated: 2005.
McLellan et al. “Vessel Sealing for Hemostasis During Pelvic Surgery” Int'l Federation of Gynecology and Obstetrics FIGO World Congress 2000, Washington, D.C.
McLellan et al. “Vessel Sealing for Hemostasis During Gynecologic Surgery” Sales/Product Literature 1999.
Int'l Search Report EP 98944778.4 dated Oct. 31, 2000.
Int'l Search Report EP 98957771 dated Aug. 9, 2001.
Int'l Search Report EP 98957773 dated Aug. 1, 2001.
Int'l Search Report EP 98958575.7 dated Sep. 20, 2002.
Int'l Search Report EP 04013772.1 dated Apr. 1, 2005.
Int'l Search Report EP 04027314.6 dated Mar. 10, 2005.
Int'l Search Report EP 04027479.7 dated Mar. 8, 2005.
Int'l Search Report EP 04027705.5 dated Feb. 3, 2005.
Int'l Search Report EP 04709033.7 dated Dec. 8, 2010.
Int'l Search Report EP 04752343.6 dated Jul. 20, 2007.
Int'l Search Report EP 05002671.5 dated Dec. 22, 2008.
Int'l Search Report EP 05002674.9 dated Jan. 16, 2009.
Int'l Search Report EP 05013463.4 dated Oct. 7, 2005.
Int'l Search Report EP 05013894 dated Feb. 3, 2006.
Int'l Search Report EP 05013895.7 dated Oct. 21, 2005.
Int'l Search Report EP 05016399.7 dated Jan. 13, 2006.
Int'l Search Report EP 05017281.6 dated Nov. 24, 2005.
Int'l Search Report EP 05019130.3 dated Oct. 27, 2005.
Int'l Search Report EP 05019429.9 dated May 6, 2008.
Int'l Search Report EP 05020532 dated Jan. 10, 2006.
Int'l Search Report EP 05020665.5 dated Feb. 27, 2006.
Int'l Search Report EP 05020666.3 dated Feb. 27, 2006.
Int'l Search Report EP 05021197.8 dated Feb. 20, 2006.
Int'l Search Report EP 05021779.3 dated Feb. 2, 2006.
Int'l Search Report EP 05021780.1 dated Feb. 23, 2006.
Int'l Search Report EP 05021937.7 dated Jan. 23, 2006.
Int'l Search Report—extended—EP 05021937.7 dated Mar. 15, 2006.
Int'l Search Report EP 05023017.6 dated Feb. 24, 2006.
Int'l Search Report EP 06002279.5 dated Mar. 30, 2006.
Int'l Search Report EP 06005185.1 dated May 10, 2006.
Int'l Search Report EP 06006716.2 dated Aug. 4, 2006.
Int'l Search Report EP 06008515.6 dated Jan. 8, 2009.
Int'l Search Report EP 06008779.8 dated Jul. 13, 2006.
Int'l Search Report EP 06014461.5 dated Oct. 31, 2006.
Int'l Search Report EP 06020574.7 dated Oct. 2, 2007.
Int'l Search Report EP 06020583.8 dated Feb. 7, 2007.
Int'l Search Report EP 06020584.6 dated Feb. 1, 2007.
Int'l Search Report EP 06020756.0 dated Feb. 16, 2007.
Int'l Search Report EP 06 024122.1 dated Apr. 16, 2007.
Int'l Search Report EP 06024123.9 dated Mar. 6, 2007.
Int'l Search Report EP 07 001480.8 dated Apr. 19, 2007.
Int'l Search Report EP 07 001488.1 dated Jun. 5, 2007.
Int'l Search Report EP 07 004429.2 dated Nov. 2, 2010.
Int'l Search Report EP 07 009026.1 dated Oct. 8, 2007.
Int'l Search Report Extended—EP 07 009029.5 dated Jul. 20, 2007.
Int'l Search Report EP 07 009321.6 dated Aug. 28, 2007.
Int'l Search Report EP 07 010672.9 dated Oct. 16, 2007.
Int'l Search Report EP 07 013779.9 dated Oct. 26, 2007.
Int'l Search Report EP 07 014016 dated Jan. 28, 2008.
Int'l Search Report EP 07 015191.5 dated Jan. 23, 2008.
Int'l Search Report EP 07 015601.3 dated Jan. 4, 2008.
Int'l Search Report EP 07 016911 dated May 28, 2010.
Int'l Search Report EP 07 016911.5 extended dated Mar. 2, 2011.
Int'l Search Report EP 07 020283.3 dated Feb. 5, 2008.
Int'l Search Report EP 07 021646.0.dated Mar. 20, 2008.
Int'l Search Report EP 07 021646.0 dated Jul. 9, 2008.
Int'l Search Report EP 07 021647.8 dated May 2, 2008.
Int'l Search Report EP 08 002692.5 dated Dec. 12, 2008.
Int'l Search Report EP 08 004655.0 dated Jun. 24, 2008.
Int'l Search Report EP 08 006732.5 dated Jul. 29, 2008.
Int'l Search Report EP 08 006917.2 dated Jul. 3, 2008.
Int'l Search Report EP 08 016539.2 dated Jan. 8, 2009.
Int'l Search Report EP 08 020807.7 dated Apr. 24, 2009.
Int'l Search Report EP 09 003677.3 dated May 4, 2009.
Int'l Search Report EP 09 003813.4 dated Aug. 3, 2009.
Int'l Search Report EP 09 004491.8 dated Sep. 9, 2009.
Int'l Search Report EP 09 005051.9 dated Jul. 6, 2009.
Int'l Search Report EP 09 005575.7 dated Sep. 9, 2009.
Int'l Search Report EP 09 010521.4 dated Dec. 16, 2009.
Int'l Search Report EP 09 011745.8 dated Jan. 5, 2010.
Int'l Search Report EP 09 012629.3 dated Dec. 8, 2009.
Int'l Search Report EP 09 012687.1 dated Dec. 23, 2009.
Int'l Search Report EP 09 012688.9 dated Dec. 28, 2009.
Int'l Search Report EP 09 152267.2 dated Jun. 15, 2009.
Int'l Search Report EP 09 152898.4 dated Jun. 10, 2009.
Int'l Search Report EP 09 154850.3 dated Jul. 20, 2009.
Int'l Search Report EP 09 160476.9 dated Aug. 4, 2009.
Int'l Search Report EP 09 164903.8 dated Aug. 21, 2009.
Int'l Search Report EP 09 165753.6 dated Nov. 11, 2009.
Int'l Search Report EP 09 168153.6 dated Jan. 14, 2010.
Int'l Search Report EP 09 168810.1 dated Feb. 2, 2010.
Int'l Search Report EP 09 172749.5 dated Dec. 4, 2009.
Int'l Search Report EP 10 000259.1 dated Jun. 30, 2010.
Int'l Search Report EP 10 011750.6 dated Feb. 1, 2011.
Int'l Search Report EP 10 157500.9 dated Jul. 30, 2010.
Int'l Search Report EP 10 159205.3 dated Jul. 7, 2010.
Int'l Search Report EP 10 160870.1 dated Aug. 9, 2010.
Int'l Search Report EP 10 161596.1 dated Jul. 28,2010.
Int'l Search Report EP 10 167655.9 dated Aug. 31, 2011.
Int'l Search Report EP 10 168705.1 dated Oct. 4, 2010.
Int'l Search Report EP 10 169647.4 dated Oct. 29, 2010.
Int'l Search Report EP 10 172005.0 dated Sep. 30, 2010.
Int'l Search Report EP 10 175956.1 dated Nov. 12, 2010.
Int'l Search Report EP 10 181034.9 dated Jan. 26, 2011.
Int'l Search Report EP 10 181575.1 dated Apr. 5, 2011.
Int'l Search Report EP 10 181969.6 dated Feb. 4, 2011.
Int'l Search Report EP 10 182019 dated Aug. 4, 2011.
Int'l Search Report EP 10 182022.3 dated Mar. 11, 2011.
Int'l Search Report EP 10 185386.9 dated Jan. 10, 2011.
Int'l Search Report EP 10 185405.7 dated Jan. 5, 2011.
Int'l Search Report EP 10 186527.7 dated Jun. 17, 2011.
lnt'l Search Report EP 10 189206.5 dated Mar. 17, 2011.
Int'l Search Report EP 10 191320.0 dated Feb. 15, 2011.
Int'l Search Report EP 11 151509.4 dated Jun. 6, 2011.
Int'l Search Report EP 11 152220.7 dated May 19, 2011.
Int'l Search Report EP 11 152360.1 dated Jun. 6, 2011.
Int'l Search Report EP 11 159771.2 dated May 28, 2010.
Int'l Search Report EP 11 161117.4 dated Jun. 30, 2011.
Int'l Search Report EP 11 161118.2 dated Oct. 12, 2011.
Int'l Search Report EP 11 164274.0 dated Aug. 3, 2011.
Int'l Search Report EP 11 164275.7 dated Aug. 25, 2011.
Int'l Search Report EP 11 167437.0 dated Aug. 8, 2011.
Int'l Search Report EP 11 168458.5 dated Jul. 29, 2011.
Int'l Search Report EP 11 173008.1 dated Nov. 4, 2011.
Int'l Search Report EP 11 179514 dated Nov. 4, 2011.
Int'l Search Report EP 11 180182.5 dated Nov. 15, 2011.
Int'l Search Report PCT/US98/18640 dated Jan. 29, 1999.
Int'l Search Report PCT/US98/23950 dated Jan. 14, 1999.
Int'l Search Report PCT/US98/24281 dated Feb. 22, 1999.
Int'l Search Report PCT/US99/24869 dated Feb. 3, 2000.
Int'l Search Report PCT/US01/11218 dated Aug. 14, 2001.
Int'l Search Report PCT/US01/11224 dated Nov. 13, 2001.
Int'l Search Report PCT/US01/11340 dated Aug. 16, 2001.
Int'l Search Report PCT/US01/11420 dated Oct. 16, 2001.
Int'l Search Report PCT/US02/01890 dated Jul. 25, 2002.
Int'l Search Report PCT/US02/11100 dated Jul. 16, 2002.
Int'l Search Report PCT/US03/08146 dated Aug. 8, 2003.
Int'l Search Report PCT/US03/18674 dated Sep. 18, 2003.
Int'l Search Report PCT/US03/18676 dated Sep. 19, 2003.
Int'l Search Report PCT/US03/28534 dated Dec. 19, 2003.
Int'l Search Report PCT/US03/28539 dated Jan. 6, 2004.
Int'l Search Report PCT/US04/03436 dated Mar. 3, 2005.
Int'l Search Report PCT/US04/13273 dated Dec. 15, 2004.
Int'l Search Report PCT/US04/15311dated Jan. 12, 2005.
Int'l Search Report PCT/US07/021438 dated Apr. 1, 2008.
Int'l Search Report PCT/US07/021440 dated Apr. 8, 2008.
Int'l Search Report PCT/US08/52460 dated Apr. 24, 2008.
Int'l Search Report PCT/US08/61498 dated Sep. 22, 2008.
Int'l Search Report PCT/US09/032690 dated Jun. 16, 2009.
Related Publications (1)
Number Date Country
20130255063 A1 Oct 2013 US