Claims
- 1. A composition from a plant matter in which the composition is enriched in at least two of the phytochemicals selected from the group consisting of isoflavones, lignans, saponins, catechins and phenolic acids.
- 2. The composition of claim 1 which essentially consists of at least 70% by weight phytochemicals selected from the group comprising isoflavones, lignans, saponins, catechins and phenolic acids.
- 3. The composition of claim 1 in which at least one of the selected phytochemicals comprises at least 10% by weight of the composition.
- 4. The composition of claim 1 which essentially consists of at least 80% by weight phytochemicals selected from the group comprising isoflavones, lignans, saponins, catechins and phenolic acids.
- 5. The composition of claim 1 which essentially consists of at least 90% by weight phytochemicals selected from the group comprising isoflavones, lignans, saponins, catechins and phenolic acids.
- 6. The composition of claim 1 in which the ratio of isoflavones to lignans is selected from the range of about 1000.1 to about 1 50.
- 7. The composition of claim 1 in which the ratio of isoflavones to saponins is selected from the range of about 1:10 to about 10:1.
- 8. The composition of claim 1 in which the ratio of isoflavones to phenolic acids is selected from the range of about 100 to 1 to about 1 to 100.
- 9. The composition of claim 1 in which the ratio of lignans to saponins is selected from the range of out 100 to 1 to about 1 to 100.
- 10. The composition of claim 1 in which the ration of lignans to phenolic acids is selected from the range of about 100 to 1 to about 1 to 100.
- 11. The composition of claim 1 in which the ratio of saponins to phenolic acids is selected from the range of about 100 to 1 to about 1 to 100.
- 12. The composition of claim 1 in which the ratio of catechins to phenolic acid is selected form a range of about 100 to 1 to about 1 to 100.
- 13. The composition of claim 1 in which the isoflavones are present in an amount from approximately 5% to approximately 90% by weight.
- 14. The composition of claim 1 in which the lignans are present in an amount from about 1% to about 70% by weight.
- 15. The composition of claim 1 in which the saponins are present in an amount from about 5% to about 70% by weight.
- 16. The composition of claim 1 in which the phenolic acids are present in an amount from about 1% to about 70% by weight.
- 17. The composition of claim 1 in which the isoflavones are selected from the group consisting essentially of genistein, daidzein, glycitein, biochanin A, formononetin, and natural modifications thereof.
- 18. The composition of claim 1 in which the lignans are selected from the group consisting essentially of matairesinol, secoisolariciresinol, lariciresinol, isolariciresinol, nordihydroguaiaretic acid, pinoresinol, olivil, and precursors of enterolactone and enterodiol and natural modifications thereof.
- 19. The composition of claim 1 in which the saponins are selected from the group consisting essentially or tomatine, soyasapogenols A, B. AC, D, E and F, soysaponin, alfalfasaponin, ginsengoside fraction 3 and 4, medicagenic acid, hederagenin, glycyrrhizin digitoning, quillaja saponin, lucernic acid, zahnic acid, and natural modifications of these compounds.
- 20. The composition of claim 1 in which the phenolic acids are selected from the group consisting essentially of chlorogenic acid, caffeic acid, ferulic acid gallic acid, sinapic acid, syringic acid, vanillic acid, coumeric acid, cinnamic acid, gentisic acid, salicylic acid, hydroxy benzoic acid and hydroxy phenyl acetic acids and derivatives thereof.
- 21. The composition of claim 1 in which catechins are selected from the group consisting essentially of catechin, epicatechin, gallocatechin, and epigallocatechin.
- 22. The composition of claim 1 in which the plant matter is selected from one or more of the group consisting essentially of soy, red clover, kudzu, flax, alfalfa, tea, and cocoa.
- 23. The composition of claim 1 in which the plant matter is soy.
- 24. The composition of claim 23, in which the soy is selected from the group consisting of soybean, soy foods, soy molasses, soy whey, soy protein, and soy flour.
- 25. A product for oral delivery comprising a composition extracted from plant matter which is enriched in two or more of the phytochemicals selected from the group consisting of isoflavones, lignans, saponins, catechins and phenolic acids.
- 26. The product of claim 5 wherein the product is selected from the group consisting of tablets, capsules, pills, concentrates, powders, liquids, and added food ingredients.
- 27. The product of claim 26 comprising tablets comprising
a. the plant matter composition; and b. a filler selected from the group consisting of sorbitol, lactose, cellulose and dicalcium phosphate.
- 28. The product of claim 27 additionally comprising a dietary supplemental nutrient selected from the group consisting of dicalcium phosphate, magnesium stearate, calcium citrate, calcium malate, other calcium sources, vitamins and minerals.
- 29. The oral delivery product of claim 27 wherein the product comprises between about 15% and about 25% by weight of the composition and between about 65% and about 85% by weight of the filler.
- 30. The product of claim 25 wherein the product comprises
a. between about 15% and about 25% by weight of the composition; b. between about 60% and about 84% by weight of the filler; and c. between about 1% and about 25% by weight of the dietary supplemental nutrient.
- 31. The oral delivery product of claim 26 comprising capsules including
a. a predetermined dosage of the plant matter composition; and b. a gelatin capsule.
- 32. The oral delivery product of claim 26 wherein the plant matter composition is extracted from plants selected from the group consisting of soy, red clover, kudzu, flax, alfalfa, tea, and cocoa.
- 33. The oral delivery product of claim 23 wherein the product comprises between about 10 milligrams and about 2000 milligrams of the plant matter composition.
- 34. A method of treating a disease selected from the group consisting of breast cancer, skin cancer, and colon cancer, said method comprising the step of administering to the subject a therapeutically effective amount of a composition extracted from plant matter which is enriched in at least one of the phytochemicals selected from the group of isoflavones, lignans, saponins, catechins and phenolic acids.
- 35. The method of claim 34 wherein the treatment is for breast cancer.
- 36. The method of claim 34 wherein the treatment is for skin cancer.
- 37. The method of claim 34 wherein the treatment is for colon cancer.
- 38. A method of treating at least one disease selected from the group consisting of urinary cancer, bladder cancer, and prostate cancer in a subject, said method comprising the step of administering to the subject a therapeutically effective amount of a composition extracted from plant matter which is enriched in at least one of the phytochemicals selected from the group of isoflavones, lignans, saponins, catechins and phenolic acids.
- 39. The method of claim 38 wherein the treatment is for urinary cancer.
- 40. The method of claim 38 wherein the treatment is for bladder cancer.
- 41. The method of claim 38 wherein the treatment is for prostate cancer.
- 42. A method of treating one disorder selected from the group consisting of migraine headache and dementia in a subject, said method comprising the step of administering to the subject a therapeutically effective amount of a composition extracted from plant matter which is enriched in at least one of the phytochemicals selected from the group of isoflavones, lignans, saponins, catechins and phenolic acids.
- 43. The method of claim 42 wherein the treatment is for migraine headache.
- 44. The method of claim 42 wherein the treatment is for dementia.
- 45. A method of reducing alcohol dependency in a subject said method comprising the step of administering to the subject a therapeutically effective amount of a composition extracted from plant matter which is enriched in at least one of the phytochemicals selected from the group of isoflavones, lignans, saponins, catechins and phenolic acids.
- 46. A method of reducing bloodstream cholesterol, reducing the risk of coronary heart disease, or modulating blood lipid profiles in a subject, said method comprising the step of administering to the subject a therapeutically effective amount of a composition extracted from plant matter which is enriched in at least one of the phytochemicals selected from the group of isoflavones, lignans, saponins, catechins, and phenolic acids.
- 47. The method of claim 46 wherein bloodstream cholesterol is reduced.
- 48. The method of claim 46 wherein the risk of coronary heart disease is reduced.
- 49. The method of claim 46 wherein blood lipid profiles are modulated.
- 50. A method of reducing or preventing hot flashes, osteoporosis, sleep disorders, vaginal dryness or premenstrual syndrome in a subject, said method comprising the step of administering to the subject a therapeutically effective amount of a composition extracted from plant matter which is enriched in at least one of the phytochemicals selected from the group of isoflavones, lignans, saponins, catechins, and phenolic acids.
- 51. The method of claim 50 wherein hot flashes are treated or prevented.
- 52. The method of claim 51 wherein osteoporosis is treated or prevented.
- 53. The method of claim 51 wherein premenstrual syndrome is treated or prevented.
- 54. The method of claim 51 wherein sleep disorders is treated or prevented.
- 55. The method of claim 51 wherein vaginal dryness is treated or prevented.
- 56. The composition of claim 1 in which the plant matter is flax.
- 57. The composition of claim 56 which consists of at least about 1% by weight lignans.
- 58. The composition of claim 56 which consists of at least about 50% by weight lignans.
- 59. The composition of claim 1 in which the selected phytochemicals are in a substantially native form.
- 60. The composition of claim 1 in which the isoflavones are in a substantially glycosylated form.
- 61. The composition of claim 1 which is added as a supplement to a food.
- 62. The composition of claim 1 which is consumed as a dietary supplement.
- 63. The composition of claim 1 in which the plant matter is tea.
- 64. The composition of claim 1 in which the plant matter is cocoa.
- 65. A composition made by the process comprising the steps of:
a. extracting a defatted material from a group of vegetable matter consisting of protein, meal, whey, molasses, solubles and germs in a solution including an alcoholic solvent to produce a slurry; b. filtering the slurry of step (a) to produce an alcoholic fraction, c. evaporating said alcoholic fraction of step (b) to produce an aqueous fraction; d. ultrafiltering said aqueous fraction of step (c); e. feeding a permeate of step (d) through a resin column; and f. collecting an effluent from said column after said wash.
- 66. The composition of claim 65 and the further step of preparing said effluent of step (f) into a form which is suitable for administering orally, said form being taken from a group consisting of a concentrate, dried powder, capsule, pellet, and pill.
- 67. The composition of claim 66 wherein said dried powder is a bulk volume of material for further manufacture to provide individual dose sizes for said oral administration.
- 68. The composition of claim 65 wherein said vegetable matter is selected from a group consisting of soy, red clover, kudzu, flax, alfalfa, tea, and cocoa.
- 69. The composition of claim 65 wherein said vegetable matter is soy.
- 70. The composition of claim 65 wherein step (c) includes a step of diluting said aqueous fraction.
- 71. The composition of claim 65 and the added step of fractionating said effluent to select at least one of the group consisting essentially of isoflavones, lignans, saponins, catechins, and phenolic acid.
- 72. The composition of claim 65 and the added step of fractionating said effluent to select isoflavones.
- 73. The composition of claim 65 wherein the solution of step (a) is about 70% ethanol and the extraction is carried out at about 40° C.
- 74. The composition of claim 65 where the evaporation of step (c) is carried out under vacuum at about 70° C.
Parent Case Info
[0001] This is a formal application that replaces provisional application Serial No. 60/060,549 filed Oct. 1, 1997.
Provisional Applications (1)
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Number |
Date |
Country |
|
60060549 |
Oct 1997 |
US |
Divisions (4)
|
Number |
Date |
Country |
Parent |
09615239 |
Jul 2000 |
US |
Child |
10136079 |
May 2002 |
US |
Parent |
09162038 |
Sep 1998 |
US |
Child |
09615239 |
Jul 2000 |
US |
Parent |
09035588 |
Mar 1998 |
US |
Child |
09615239 |
Jul 2000 |
US |
Parent |
08614545 |
Mar 1996 |
US |
Child |
08868629 |
Jun 1997 |
US |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
08868629 |
Jun 1997 |
US |
Child |
09035588 |
Mar 1998 |
US |