Claims
- 1. A method of preventing pregnancy in female humans experiencing a reproductive cycle which comprises administering to said female human in unit dosage form an effective amount to prevent pregnancy of a compound of the formula selected from the group consisting of: ##SPC5##
- 2. The method of claim 1 wherein the compound is administered for a time effective to prevent pregnancy and the dosage of the compound is about 0.01 to 10 mg. per kilogram of body weight per day.
- 3. The method of claim 2 wherein the compound is administered during a reproductive cycle for 20 to 25 days beginning on the fifth day after the first day of menstruation.
- 4. The method of claim 2 wherein the compound is administered orally.
- 5. The method of claim 4 wherein the compound is administered in the amount of about 50 to 250 mg. per day.
- 6. The method of claim 2 wherein the compound is administered for from about 70 to 100% of the reproductive period including the fertile period.
- 7. The method of claim 2 wherein the compound is ##SPC6##
- 8. The method of claim 2 wherein the compound is ##SPC7##
- 9. The method of claim 8 wherein the compound is the low melting diastereoisomer having a melting point of about 155.degree.C.
- 10. The method of claim 8 wherein the compound is the high melting diastereoisomer having a melting point of 178.degree.-180.degree.C.
Parent Case Info
This application is a continuation of application Ser. No. 273,439, filed July 20, 1972, now abandoned; which in turn is a continuation of application Ser. No. 28,967, filed Apr. 15, 1970, now abandoned; which in turn is a continuation-in-part of application Ser. No. 512,111, filed Dec. 7, 1965, now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
3239341 |
Hodge et al. |
Mar 1966 |
|
3239345 |
Hodge et al. |
Mar 1966 |
|
3239354 |
Hodge et al. |
Mar 1966 |
|
Non-Patent Literature Citations (1)
Entry |
Goldzieher et al. - Western Journal of Surgery, Obstetrics & Gynecology, vol. 71, (1963) p. 187. |
Continuations (2)
|
Number |
Date |
Country |
Parent |
273439 |
Jul 1972 |
|
Parent |
28967 |
Apr 1970 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
512111 |
Dec 1965 |
|