Budd, Keith “The use of the opiate antagonist, naloxone, in the treatment of intractable pain” Neuropeptides (edinburgh) (1985), 5 (4-6), 419-22 ISSN: 0143-4179.* |
de Cazanove, et al. “Determination of Nalbuphine in Human Plasma by High-performance Liquid Chromatography with Electrochemical Detection Application to a Pharmacokinetic Study” J. of Chromatography B (1997) vol. 690, pp. 203-210. |
Dube, et al. “Determination of Nalbuphine by High-performance Liquid Chromatography with Electrochemical Detection: Application to Clinical Samples from Post-operative Patients” J. of Chromatography (1988) vol. 427, pp. 113-120. |
Gear, et al. “Action of Naloxone on Gender-dependent Analgesic and Antianalgesic Effects of Nalbuphine in Humans” J. of Pain (2000), vol. 1(2), pp. 122-127. |
Gear, et al. “The Kappa Opioid Nalbuphine Produces Genger- and Dose-dependent Analgesia and Antianalgesia in Patients with Postoperative Pain” Pain (1999) vol. 83, pp. 339-345. |
Ho, et al. “Determination of Nalbuphine by High-performance liquid Chromatography with Ultraviolet Detection: Application of Human and Rabbit Pharmacokinetic Studies” J. of Chromatography B (1996) vol. 678, pp. 289-269. |
Levine, et al. “Potentiation of Pentazocine Analgesia by Low-dose Naloxone” J. Clin. Invest. (Nov. 1998) vol. 82, pp. 1574-1577. |
Lo, et al. “The Disposition and Bioavailability of Intravenous and Oral Nalbuphine in Healthy Volunteers” J. Clin. Pharmacol. (1987) vol. 27, pp. 866-873. |
Nicolle, et al. “Rapid and Sensitive High-performance Liquid Chromatographic Assay for Nalbuphine in Plasma” J. of Chromatography B (1995) vol. 663, pp. 111-117. |
Pao, et al. “High-performance Liquid Chromatographic Method for the Simultaneous Determination of Nalbuphine and its Prodrug, Sebacoyl Dinalburphine Ester, in Dog Plasma and Application to Pharmacokinetic Studies in Dogs”J. of Chromatography B (2000) vol. 746, pp. 241-247. |
Regents of the University of California, “Finding Could Lead to Morphine Alternative” Daybreak http://www.uscf.edu/today/ (2000). |
Sung, et al. “Delivery of Nalbuphine and its Prodrugs Across Skin by Passive Diffusion and Iontophoresis” J. of Controlled Release (2000) vol. 67, pp. 1-8. |
Wetzelsberger, et al. “Internally Standardized Method for the Determination of Nalbuphine in Human Plasma by Means of High Performance Liquid Chromatography with Electrochemical CoulOmetric Detection” Arzneim-Forsch/Drug Res. (1988) vol. 38(11), pp. 1768-1771. |
Hussain et al., Pharm. Res. 5: 615 (1998). |
Hussain et al., Pharm. Res. 5:113 (1988). |
Hussain et al., J. Pharm. Sci. 76: 356 (1987). |
The Merck Index, 12th edition, S. Budavari, ed., 1091-1093 (1996). |
Rust, L. A. et al.: “Intrathecal narcotics for obstetric analgesia in a community hospital”, American Journal of Obstetrics and Bynecology, (Jun. 1994) 170 (6) 1643-6; Discussion 1646-8, XP008005676, abstract p. 1644, col. 1. |
Lehmann, K.A.: “Opioids: Overview on action, interaction and toxicity”, Supportive Care in Cancer, (1997) 5/6 (439-444), XP001086567, figure 3, tables 2, 3. |
Gerak, L. R. et al.: “Changes in sensitivity to the rate-decreasing effects of opioids in pigeons treated acutely or chronically with nalbuphine”, Behavioural Pharmacology, (1996) 7/5 (437-447), XP008005675, abstract, col. 1. |
Barsan, William G. et al.: “Duration of Antagonistic Effects of Nalmafene and Naloxone in Opiate-Induced Sedation for Emergency Department Procedures”, American Journal of Emergency Medicine, vol. 7, No. 2 (Mar. 1989). |
Konieczko, K. M. et al.: “Antagonism of Morphine-Induced Respiratory Depression with Nalmefene”, British Journal of Anaesthesia, 61, 318-323 (1988). |
France, Charles P. et al.: “Morphine, Saline and Naltrexone Discrimination in Morphine-Treated Pigeons”, The Journal of Pharmacology and Experimental Therapeutics, vol. 242, No. 1 (1987). |