Claims
- 1. A method of treating an angiogenesis-dependent tumor in a mammal, comprising administering an effective amount of O-(N-chloroacetylcarbamoyl)fumagillol, O-(N-chloroacetylcarbnmoyl)dihydrofumagillol or O-(N-chloroacetylcarbamoyl)-6'b-hydroxyfumagillol to said mammal.
- 2. The method of claim 1, wherein the tumor is Kaposi's sarcoma.
- 3. The method of claim 1 wherein the tumor is breast cancer.
- 4. A method of treating an angiogenesis-dependent cancer in an animal, which comprises inhibiting angiogenesis by administering O-(N-chloroacetylcarbainoyl)fumagillol, O-(N-chloroacetylcarbamoyl)dihydrofumagillol or O-(N-choroacetylcarbamoyl)-6'b-hydroxyfumagillol to the animal.
- 5. The method of claim 4, wherein the tumor is Kaposi's sarcoma.
- 6. The method of claim 4, wherein the tumor is breast cancer.
Parent Case Info
This is a Continuation-In-Part of application Ser. No. 07/811,880 filed Dec. 19, 1991, now abandoned which is a Continuation of application Ser. No. 07/391,980 filed Aug. 10, 1989, now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4954496 |
Oku et al. |
Sep 1990 |
|
5698586 |
Kishimoto et al. |
Dec 1997 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
0 325 199 |
Jul 1989 |
EPX |
Continuations (1)
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Number |
Date |
Country |
Parent |
391980 |
Aug 1989 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
811880 |
Dec 1991 |
|