Claims
- 1. A method for treating an animal afflicted with a viral infection comprising administering to said animal an effective anti-viral amount of a platinum coordination compound having the formula:
- [Pt(II)A.sub.x (OOC).sub.2 --CRR.sub.1 ]
- wherein:
- x=1 or 2;
- R and R.sub.1 are selected from the group consisting of H, lower alkyl, aryl, aralkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxy, OH, or combine with the carbon atom to form a cycloalkyl or cycloalkenyl;
- when x=1, A is HR.sub.2 N--CHR.sub.3 --CHR.sub.4 --NR.sub.5 H and when x=2, A is H.sub.2 NR.sub.6 or an amino acid, wherein R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are the same or different and are selected from the group consisting of H, CH.sub.3, C.sub.2 H.sub.5, hydroxy and lower alkoxy, provided that R.sub.2 and R.sub.5 may also be aryl or aralkyl and each R.sub.6 is the same or different and is selected from the group consisting of H, lower alkyl, aryl, aralkyl, hydroxy lower alkyl, hydroxyl- and alkoxyl-amines, and alkoxyl alkyl amines, all of said alkyl and alkoxy groups being lower alkyl and alkoxy groups.
- 2. A method according to claim 1 wherein the amount of said compound administered is from about 0.1 to about 100 mg/kg of body weight of said animal.
- 3. A method according to claim 1 wherein said compound is administered parenterally.
Parent Case Info
This application is a division of application Ser. No. 773,216, filed Mar. 1, 1977 now U.S. Pat. No. 4,258,051 which is a division of application Ser. No. 540,109, filed Jan. 10, 1975 now U.S. Pat. No. 4,053,587.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4140707 |
Cleare et al. |
Feb 1979 |
|
Non-Patent Literature Citations (1)
Entry |
Cleare et al., Platinum Metal Rev. 17, pp. 2-13, Mar. 8, 1973. |
Divisions (2)
|
Number |
Date |
Country |
Parent |
773216 |
Mar 1977 |
|
Parent |
540109 |
Jan 1975 |
|